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2021, volume 597, articles 7878

Stem cells pp. S5-S5

Richard Hodson

Stem cells: highlights from research pp. S6-S7

Anthony King

The promise and potential of stem cells in Parkinson’s disease pp. S8-S10

Lauren Gravitz

Stem cells and spinal-cord injuries: an intricate issue pp. S11-S11

Lauren Gravitz

The chimaera challenge pp. S12-S14

Liam Drew

The next frontier for human embryo research pp. S15-S17

Elizabeth Svoboda

Why stem cells might save the northern white rhino pp. S18-S19

Julianna Photopoulos

Stem-cell start-ups seek to crack the mass-production problem pp. S20-S21

Eric Bender

The rise of the assembloid pp. S22-S23

Charlie Schmidt

Reversing blindness with stem cells pp. S24-S26

Neil Savage

The incoming Afghan government must allow immunizations pp. 595-595

Zulfiqar A. Bhutta

Ancient footprints could be oldest traces of humans in the Americas pp. 601-602

Ewen Callaway

Closest known relatives of virus behind COVID-19 found in Laos pp. 603-603

Smriti Mallapaty

Resistance to front-line malaria drugs confirmed in Africa pp. 604-604

Max Kozlov

Young people’s climate anxiety revealed in landmark survey pp. 605-605

Tosin Thompson

COVID vaccine immunity is waning — how much does that matter? pp. 606-607

Elie Dolgin

Starting up in science: two biologists struggle to launch their labs pp. 608-613

Kerri Smith, Heidi Ledford and Richard Van Noorden

Starting up in science: an agonizing search for cash confronts two labs pp. 613-618

Kerri Smith, Heidi Ledford and Richard Van Noorden

Starting up in science: two labs face the pandemic and another shock pp. 618-623

Kerri Smith, Heidi Ledford and Richard Van Noorden

Transformations in medical care were never easy or safe pp. 625-626

Hannah Wunsch

From gold to Bitcoin and beyond pp. 626-627

Paola Subacchi

Antony Hewish (1924–2021) pp. 628-628

Malcolm Longair

Microsoft’s million-tonne CO2-removal purchase — lessons for net zero pp. 629-632

Lucas Joppa, Amy Luers, Elizabeth Willmott, S. Julio Friedmann, Steven P. Hamburg and Rafael Broze

Mental health: build predictive models to steer policy pp. 633-636

Jo-An Occhipinti, Adam Skinner, P. Murali Doraiswamy, Cameron Fox, Helen Herrman, Shekhar Saxena, Elisha London, Yun Ju Christine Song and Ian B. Hickie

Heat management with a twist in layered materials pp. 637-638

Mariusz Zdrojek

Pollination advantage of rare plants unveiled pp. 638-639

Marcelo A. Aizen

Electron crystals come under the microscope pp. 640-641

Carmen Rubio-Verdú

Insights into the origins of pancreatic cancer pp. 641-642

Laura D. Wood and Anirban Maitra

Protein condensates provide a platform for controlling chromatin pp. 642-644

David Lara-Astiaso and Brian J. P. Huntly

The importance of lake breach floods for valley incision on early Mars pp. 645-649

Timothy A. Goudge, Alexander M. Morgan, Gaia Stucky de Quay and Caleb I. Fassett

Imaging two-dimensional generalized Wigner crystals pp. 650-654

Hongyuan Li, Shaowei Li, Emma C. Regan, Danqing Wang, Wenyu Zhao, Salman Kahn, Kentaro Yumigeta, Mark Blei, Takashi Taniguchi, Kenji Watanabe, Sefaattin Tongay, Alex Zettl, Michael F. Crommie and Feng Wang

Non-Hermitian topological whispering gallery pp. 655-659

Bolun Hu, Zhiwang Zhang, Haixiao Zhang, Liyang Zheng, Wei Xiong, Zichong Yue, Xiaoyu Wang, Jianyi Xu, Ying Cheng, Xiaojun Liu and Johan Christensen

Extremely anisotropic van der Waals thermal conductors pp. 660-665

Shi En Kim, Fauzia Mujid, Akash Rai, Fredrik Eriksson, Joonki Suh, Preeti Poddar, Ariana Ray, Chibeom Park, Erik Fransson, Yu Zhong, David A. Muller, Paul Erhart, David G. Cahill and Jiwoong Park

The role of charge recombination to triplet excitons in organic solar cells pp. 666-671

Alexander J. Gillett, Alberto Privitera, Rishat Dilmurat, Akchheta Karki, Deping Qian, Anton Pershin, Giacomo Londi, William K. Myers, Jaewon Lee, Jun Yuan, Seo-Jin Ko, Moritz K. Riede, Feng Gao, Guillermo C. Bazan, Akshay Rao, Thuc-Quyen Nguyen, David Beljonne and Richard H. Friend

Skilful precipitation nowcasting using deep generative models of radar pp. 672-677

Suman Ravuri, Karel Lenc, Matthew Willson, Dmitry Kangin, Remi Lam, Piotr Mirowski, Megan Fitzsimons, Maria Athanassiadou, Sheleem Kashem, Sam Madge, Rachel Prudden, Amol Mandhane, Aidan Clark, Andrew Brock, Karen Simonyan, Raia Hadsell, Niall Robinson, Ellen Clancy, Alberto Arribas and Shakir Mohamed

Mercury stable isotopes constrain atmospheric sources to the ocean pp. 678-682

Martin Jiskra, Lars-Eric Heimbürger-Boavida, Marie-Maëlle Desgranges, Mariia V. Petrova, Aurélie Dufour, Beatriz Ferreira-Araujo, Jérémy Masbou, Jérôme Chmeleff, Melilotus Thyssen, David Point and Jeroen E. Sonke

Fine-root traits in the global spectrum of plant form and function pp. 683-687

Carlos P. Carmona, C. Guillermo Bueno, Aurele Toussaint, Sabrina Träger, Sandra Díaz, Mari Moora, Alison D. Munson, Meelis Pärtel, Martin Zobel and Riin Tamme

Pollinators contribute to the maintenance of flowering plant diversity pp. 688-692

Na Wei, Rainee L. Kaczorowski, Gerardo Arceo-Gómez, Elizabeth M. O’Neill, Rebecca A. Hayes and Tia-Lynn Ashman

Genetic and epigenetic coordination of cortical interneuron development pp. 693-697

Kathryn C. Allaway, Mariano I. Gabitto, Orly Wapinski, Giuseppe Saldi, Chen-Yu Wang, Rachel C. Bandler, Sherry Jingjing Wu, Richard Bonneau and Gord Fishell

Rational design of a new antibiotic class for drug-resistant infections pp. 698-702

Thomas F. Durand-Reville, Alita A. Miller, John P. O’Donnell, Xiaoyun Wu, Mark A. Sylvester, Satenig Guler, Ramkumar Iyer, Adam B. Shapiro, Nicole M. Carter, Camilo Velez-Vega, Samir H. Moussa, Sarah M. McLeod, April Chen, Angela M. Tanudra, Jing Zhang, Janelle Comita-Prevoir, Jan A. Romero, Hoan Huynh, Andrew D. Ferguson, Peter S. Horanyi, Stephen J. Mayclin, Henry S. Heine, George L. Drusano, Jason E. Cummings, Richard A. Slayden and Ruben A. Tommasi

Emergence and expansion of SARS-CoV-2 B.1.526 after identification in New York pp. 703-708

Medini K. Annavajhala, Hiroshi Mohri, Pengfei Wang, Manoj Nair, Jason E. Zucker, Zizhang Sheng, Angela Gomez-Simmonds, Anne L. Kelley, Maya Tagliavia, Yaoxing Huang, Trevor Bedford, David D. Ho and Anne-Catrin Uhlemann

A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis pp. 709-714

Martina Absinta, Dragan Maric, Marjan Gharagozloo, Thomas Garton, Matthew D. Smith, Jing Jin, Kathryn C. Fitzgerald, Anya Song, Poching Liu, Jing-Ping Lin, Tianxia Wu, Kory R. Johnson, Dorian B. McGavern, Dorothy P. Schafer, Peter A. Calabresi and Daniel S. Reich

Acinar cell clonal expansion in pancreas homeostasis and carcinogenesis pp. 715-719

Patrick Neuhöfer, Caitlin M. Roake, Stewart J. Kim, Ryan J. Lu, Robert B. West, Gregory W. Charville and Steven E. Artandi

Programmable RNA targeting with the single-protein CRISPR effector Cas7-11 pp. 720-725

Ahsen Özcan, Rohan Krajeski, Eleonora Ioannidi, Brennan Lee, Apolonia Gardner, Kira S. Makarova, Eugene V. Koonin, Omar O. Abudayyeh and Jonathan S. Gootenberg

UTX condensation underlies its tumour-suppressive activity pp. 726-731

Bi Shi, Wei Li, Yansu Song, Zhenjia Wang, Rui Ju, Aleksandra Ulman, Jing Hu, Francesco Palomba, Yanfang Zhao, John Philip Le, William Jarrard, David Dimoff, Michelle A. Digman, Enrico Gratton, Chongzhi Zang and Hao Jiang

Structure-based classification predicts drug response in EGFR-mutant NSCLC pp. 732-737

Jacqulyne P. Robichaux, Xiuning Le, R. S. K. Vijayan, J. Kevin Hicks, Simon Heeke, Yasir Y. Elamin, Heather Y. Lin, Hibiki Udagawa, Ferdinandos Skoulidis, Hai Tran, Susan Varghese, Junqin He, Fahao Zhang, Monique B. Nilsson, Lemei Hu, Alissa Poteete, Waree Rinsurongkawong, Xiaoshan Zhang, Chenghui Ren, Xiaoke Liu, Lingzhi Hong, Jianjun Zhang, Lixia Diao, Russell Madison, Alexa B. Schrock, Jennifer Saam, Victoria Raymond, Bingliang Fang, Jing Wang, Min Jin Ha, Jason B. Cross, Jhanelle E. Gray and John V. Heymach

How to shrink the gap that holds Black scientists back pp. 739-740

Ingrid Torjesen

Stress testing avocados pp. 742-742

Virginia Gewin

2021, volume 597, articles 7877

A finding of sex similarities rather than differences in COVID-19 outcomes pp. E7-E9

Heather Shattuck-Heidorn, Ann Caroline Danielsen, Annika Gompers, Joseph Dov Bruch, Helen Zhao, Marion Boulicault, Jamie Marsella and Sarah S. Richardson

Reply to: A finding of sex similarities rather than differences in COVID-19 outcomes pp. E10-E11

Takehiro Takahashi, Mallory K. Ellingson, Patrick Wong, Benjamin Israelow, Carolina Lucas, Jon Klein, Julio Silva, Tianyang Mao, Ji Eun Oh, Maria Tokuyama, Peiwen Lu, Arvind Venkataraman, Annsea Park, Feimei Liu, Amit Meir, Jonathan Sun, Eric Y. Wang, Arnau Casanovas-Massana, Anne L. Wyllie, Chantal B. F. Vogels, Rebecca Earnest, Sarah Lapidus, Isabel M. Ott, Adam J. Moore, Albert Shaw, John B. Fournier, Camila D. Odio, Shelli Farhadian, Charles Cruz, Nathan D. Grubaugh, Wade L. Schulz, Aaron M. Ring, Albert I. Ko, Saad B. Omer and Akiko Iwasaki

Author Correction: CO2 doping of organic interlayers for perovskite solar cells pp. E12-E12

Jaemin Kong, Yongwoo Shin, Jason A. Röhr, Hang Wang, Juan Meng, Yueshen Wu, Adlai Katzenberg, Geunjin Kim, Dong Young Kim, Tai- De Li, Edward Chau, Francisco Antonio, Tana Siboonruang, Sooncheol Kwon, Kwanghee Lee, Jin Ryoun Kim, Miguel A. Modestino, Hailiang Wang and André D. Taylor

Hurricane Ida shows the one-two punch of poverty and climate change pp. 449-449

Catherine Coleman Flowers

The fight to manufacture COVID vaccines in lower-income countries pp. 455-457

Amy Maxmen

Did the coronavirus jump from animals to people twice? pp. 458-459

Smriti Mallapaty

Australian bush fires belched out immense quantity of carbon pp. 459-460

Smriti Mallapaty

New type of dark energy could solve Universe expansion mystery pp. 460-461

Davide Castelvecchi

Swedish research misconduct agency swamped with cases in first year pp. 461-461

Holly Else

How far will global population rise? Researchers can’t agree pp. 462-465

David Adam

How dangerous is Africa’s explosive Lake Kivu? pp. 466-469

Nicola Jones

Who is allowed to have wild ideas in physics? pp. 471-472

Anil Ananthaswamy

A meander around many circulatory systems pp. 472-474

Henry Nicholls

Intellectual bees, doyenne of dark matter, and mathematical grief: Books in brief pp. 473-473

Andrew Robinson

Afghanistan: Taliban’s return imperils maternal health pp. 475-475

Shohra Qaderi, Attaullah Ahmadi and Don Eliseo Lucero-Prisno

Funders: cover APCs for African scholars — and do more pp. 475-475

Bård Vegar Solhjell, Kjersti Thorkildsen and Grete Benjaminsen

Changing the wrapping won’t fix genetic-racism package pp. 475-475

Latifa Jackson, Krystal S. Tsosie and Keolu Fox

Modern Polynesian genomes offer clues to early eastward migrations pp. 477-478

Patrick V. Kirch

Ebola virus can lie low and reactivate after years in human survivors pp. 478-480

Robert F. Garry

Seed-inspired vehicles take flight pp. 480-481

E. Farrell Helbling

Policy, drought and fires combine to affect biodiversity in the Amazon basin pp. 481-483

Thomas W. Gillespie

Light detection nears its quantum limit pp. 483-484

Sebastian Klembt

Quenching of star formation from a lack of inflowing gas to galaxies pp. 485-488

Katherine E. Whitaker, Christina C. Williams, Lamiya Mowla, Justin S. Spilker, Sune Toft, Desika Narayanan, Alexandra Pope, Georgios E. Magdis, Pieter G. Dokkum, Mohammad Akhshik, Rachel Bezanson, Gabriel B. Brammer, Joel Leja, Allison Man, Erica J. Nelson, Johan Richard, Camilla Pacifici, Keren Sharon and Francesco Valentino

Normal, dust-obscured galaxies in the epoch of reionization pp. 489-492

Y. Fudamoto, P. A. Oesch, S. Schouws, M. Stefanon, R. Smit, R. J. Bouwens, R. A. A. Bowler, R. Endsley, V. Gonzalez, H. Inami, I. Labbe, D. Stark, M. Aravena, L. Barrufet, E. da Cunha, P. Dayal, A. Ferrara, L. Graziani, J. Hodge, A. Hutter, Y. Li, I. De Looze, T. Nanayakkara, A. Pallottini, D. Riechers, R. Schneider, G. Ucci, P. van der Werf and C. White

Single-photon nonlinearity at room temperature pp. 493-497

Anton V. Zasedatelev, Anton V. Baranikov, Denis Sannikov, Darius Urbonas, Fabio Scafirimuto, Vladislav Yu. Shishkov, Evgeny S. Andrianov, Yurii E. Lozovik, Ullrich Scherf, Thilo Stöferle, Rainer F. Mahrt and Pavlos G. Lagoudakis

Electron phase-space control in photonic chip-based particle acceleration pp. 498-502

R. Shiloh, J. Illmer, T. Chlouba, P. Yousefi, N. Schönenberger, U. Niedermayer, A. Mittelbach and P. Hommelhoff

Three-dimensional electronic microfliers inspired by wind-dispersed seeds pp. 503-510

Bong Hoon Kim, Kan Li, Jin-Tae Kim, Yoonseok Park, Hokyung Jang, Xueju Wang, Zhaoqian Xie, Sang Min Won, Hong-Joon Yoon, Geumbee Lee, Woo Jin Jang, Kun Hyuck Lee, Ted S. Chung, Yei Hwan Jung, Seung Yun Heo, Yechan Lee, Juyun Kim, Tengfei Cai, Yeonha Kim, Poom Prasopsukh, Yongjoon Yu, Xinge Yu, Raudel Avila, Haiwen Luan, Honglie Song, Feng Zhu, Ying Zhao, Lin Chen, Seung Ho Han, Jiwoong Kim, Soong Ju Oh, Heon Lee, Chi Hwan Lee, Yonggang Huang, Leonardo P. Chamorro, Yihui Zhang and John A. Rogers

Three-dimensional magnetic stripes require slow cooling in fast-spread lower ocean crust pp. 511-515

Sarah M. Maher, Jeffrey S. Gee, Michael J. Cheadle and Barbara E. John

How deregulation, drought and increasing fire impact Amazonian biodiversity pp. 516-521

Xiao Feng, Cory Merow, Zhihua Liu, Daniel S. Park, Patrick R. Roehrdanz, Brian Maitner, Erica A. Newman, Brad L. Boyle, Aaron Lien, Joseph R. Burger, Mathias M. Pires, Paulo M. Brando, Mark B. Bush, Crystal N. H. McMichael, Danilo M. Neves, Efthymios I. Nikolopoulos, Scott R. Saleska, Lee Hannah, David D. Breshears, Tom P. Evans, José R. Soto, Kacey C. Ernst and Brian J. Enquist

Paths and timings of the peopling of Polynesia inferred from genomic networks pp. 522-526

Alexander G. Ioannidis, Javier Blanco-Portillo, Karla Sandoval, Erika Hagelberg, Carmina Barberena-Jonas, Adrian V. S. Hill, Juan Esteban Rodríguez-Rodríguez, Keolu Fox, Kathryn Robson, Sonia Haoa-Cardinali, Consuelo D. Quinto-Cortés, Juan Francisco Miquel-Poblete, Kathryn Auckland, Tom Parks, Abdul Salam M. Sofro, María C. Ávila-Arcos, Alexandra Sockell, Julian R. Homburger, Celeste Eng, Scott Huntsman, Esteban G. Burchard, Christopher R. Gignoux, Ricardo A. Verdugo, Mauricio Moraga, Carlos D. Bustamante, Alexander J. Mentzer and Andrés Moreno-Estrada

Rare variant contribution to human disease in 281,104 UK Biobank exomes pp. 527-532

Quanli Wang, Ryan S. Dhindsa, Keren Carss, Andrew R. Harper, Abhishek Nag, Ioanna Tachmazidou, Dimitrios Vitsios, Sri V. V. Deevi, Alex Mackay, Daniel Muthas, Michael Hühn, Susan Monkley, Henric Olsson, Sebastian Wasilewski, Katherine R. Smith, Ruth March, Adam Platt, Carolina Haefliger and Slavé Petrovski

Bioaccumulation of therapeutic drugs by human gut bacteria pp. 533-538

Martina Klünemann, Sergej Andrejev, Sonja Blasche, Andre Mateus, Prasad Phapale, Saravanan Devendran, Johanna Vappiani, Bernd Simon, Timothy A. Scott, Eleni Kafkia, Dimitrios Konstantinidis, Katharina Zirngibl, Eleonora Mastrorilli, Manuel Banzhaf, Marie-Therese Mackmull, Felix Hövelmann, Leo Nesme, Ana Rita Brochado, Lisa Maier, Thomas Bock, Vinita Periwal, Manjeet Kumar, Yongkyu Kim, Melanie Tramontano, Carsten Schultz, Martin Beck, Janosch Hennig, Michael Zimmermann, Daniel C. Sévin, Filipe Cabreiro, Mikhail M. Savitski, Peer Bork, Athanasios Typas and Kiran R. Patil

Resurgence of Ebola virus in 2021 in Guinea suggests a new paradigm for outbreaks pp. 539-543

Alpha Kabinet Keita, Fara R. Koundouno, Martin Faye, Ariane Düx, Julia Hinzmann, Haby Diallo, Ahidjo Ayouba, Frederic Le Marcis, Barré Soropogui, Kékoura Ifono, Moussa M. Diagne, Mamadou S. Sow, Joseph A. Bore, Sebastien Calvignac-Spencer, Nicole Vidal, Jacob Camara, Mamadou B. Keita, Annick Renevey, Amadou Diallo, Abdoul K. Soumah, Saa L. Millimono, Almudena Mari-Saez, Mamadou Diop, Ahmadou Doré, Fodé Y. Soumah, Kaka Kourouma, Nathalie J. Vielle, Cheikh Loucoubar, Ibrahima Camara, Karifa Kourouma, Giuditta Annibaldis, Assaïtou Bah, Anke Thielebein, Meike Pahlmann, Steven T. Pullan, Miles W. Carroll, Joshua Quick, Pierre Formenty, Anais Legand, Karla Pietro, Michael R. Wiley, Noel Tordo, Christophe Peyrefitte, John T. McCrone, Andrew Rambaut, Youssouf Sidibé, Mamadou D. Barry, Madeleine Kourouma, Cé D. Saouromou, Mamadou Condé, Moussa Baldé, Moriba Povogui, Sakoba Keita, Mandiou Diakite, Mamadou S. Bah, Amadou Sidibe, Dembo Diakite, Fodé B. Sako, Fodé A. Traore, Georges A. Ki-Zerbo, Philippe Lemey, Stephan Günther, Liana E. Kafetzopoulou, Amadou A. Sall, Eric Delaporte, Sophie Duraffour, Ousmane Faye, Fabian H. Leendertz, Martine Peeters, Abdoulaye Toure and N’. Faly Magassouba

An engineered IL-2 partial agonist promotes CD8+ T cell stemness pp. 544-548

Fei Mo, Zhiya Yu, Peng Li, Jangsuk Oh, Rosanne Spolski, Liang Zhao, Caleb R. Glassman, Tori N. Yamamoto, Yun Chen, Filip M. Golebiowski, Dalton Hermans, Sonia Majri-Morrison, Lora K. Picton, Wei Liao, Min Ren, Xiaoxuan Zhuang, Suman Mitra, Jian-Xin Lin, Luca Gattinoni, Jonathan D. Powell, Nicholas P. Restifo, K. Christopher Garcia and Warren J. Leonard

Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis pp. 549-554

Roarke A. Kamber, Yoko Nishiga, Bhek Morton, Allison M. Banuelos, Amira A. Barkal, Felipe Vences-Catalán, Mingxin Gu, Daniel Fernandez, Jose A. Seoane, David Yao, Katherine Liu, Sijie Lin, Kaitlyn Spees, Christina Curtis, Livnat Jerby-Arnon, Irving L. Weissman, Julien Sage and Michael C. Bassik

Using DNA sequencing data to quantify T cell fraction and therapy response pp. 555-560

Robert Bentham, Kevin Litchfield, Thomas B. K. Watkins, Emilia L. Lim, Rachel Rosenthal, Carlos Martínez-Ruiz, Crispin T. Hiley, Maise Al Bakir, Roberto Salgado, David A. Moore, Mariam Jamal-Hanjani, Charles Swanton and Nicholas McGranahan

Single-cell Ribo-seq reveals cell cycle-dependent translational pausing pp. 561-565

Michael VanInsberghe, Jeroen Berg, Amanda Andersson-Rolf, Hans Clevers and Alexander Oudenaarden

Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB pp. 566-570

Olga A. Esakova, Tyler L. Grove, Neela H. Yennawar, Arthur J. Arcinas, Bo Wang, Carsten Krebs, Steven C. Almo and Squire J. Booker

Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia pp. 571-576

Christopher J. Draper-Joyce, Rebecca Bhola, Jinan Wang, Apurba Bhattarai, Anh T. N. Nguyen, India Cowie-Kent, Kelly O’Sullivan, Ling Yeong Chia, Hariprasad Venugopal, Celine Valant, David M. Thal, Denise Wootten, Nicolas Panel, Jens Carlsson, Macdonald J. Christie, Paul J. White, Peter Scammells, Lauren T. May, Patrick M. Sexton, Radostin Danev, Yinglong Miao, Alisa Glukhova, Wendy L. Imlach and Arthur Christopoulos

Discovering allyship at a historically Black university pp. 577-578

Adrienne Nugent

Cash boost looms for historically Black US colleges and universities pp. 578-579

Chris Woolston

Single-cell proteomics takes centre stage pp. 580-582

Jeffrey M. Perkel

Preserving pieces of history in eggshells and birds’ nests pp. 586-586

Richa Malhotra

2021, volume 597, articles 7876

Biology must generate ideas as well as data pp. 305-305

Paul Nurse

China prepares to test thorium-fuelled nuclear reactor pp. 311-312

Smriti Mallapaty

Hurricane Ida forces Louisiana researchers to rethink their future pp. 313-314

Max Kozlov

How COVID is derailing the fight against HIV, TB and malaria pp. 314-314

Leslie Roberts

Pivotal climate summit dogged by COVID and equity concerns pp. 315-315

Jeff Tollefson

Most fossil-fuel reserves must remain untapped to hit 1.5 °C warming goal pp. 316-317

Bianca Nogrady

Success! Mars rover finally collects its first rock core pp. 317-317

Alexandra Witze

The tangled history of mRNA vaccines pp. 318-324

Elie Dolgin

Marauding elephants, menacing macaques and epicurean bears pp. 325-326

Josie Glausiusz

Edmond Fischer (1920–2021) pp. 328-328

Philip Cohen

Reproducibility: expect less of the scientific paper pp. 329-331

Olavo B. Amaral and Kleber Neves

Africa: invest in local manufacturing of COVID-19 vaccines pp. 332-332

James Ayodele and Sylvain Boko

Preventing spillover as a key strategy against pandemics pp. 332-332

Neil M. Vora, Nigel Sizer and Aaron Bernstein

Anthropocene: event or epoch? pp. 332-332

Andrew M. Bauer, Matthew Edgeworth, Lucy E. Edwards, Erle C. Ellis, Philip Gibbard and Dorothy J. Merritts

Afghanistan: conflict risks local and global health pp. 332-332

Muhammad Jawad Noon

Triple-decker layered perovskite materials pp. 333-334

Roman Krahne and Milena P. Arciniegas

Mutation fingerprints encode cellular histories pp. 334-336

Kamila Naxerova

Text-message nudges encourage COVID vaccination pp. 336-337

Mitesh S. Patel

Traces of a series of human dispersals through Arabia pp. 338-339

Robin Dennell

The diffuse γ-ray background is dominated by star-forming galaxies pp. 341-344

Matt A. Roth, Mark R. Krumholz, Roland M. Crocker and Silvia Celli

Quantum criticality in twisted transition metal dichalcogenides pp. 345-349

Augusto Ghiotto, En-Min Shih, Giancarlo S. S. G. Pereira, Daniel A. Rhodes, Bumho Kim, Jiawei Zang, Andrew J. Millis, Kenji Watanabe, Takashi Taniguchi, James C. Hone, Lei Wang, Cory R. Dean and Abhay N. Pasupathy

Continuous Mott transition in semiconductor moiré superlattices pp. 350-354

Tingxin Li, Shengwei Jiang, Lizhong Li, Yang Zhang, Kaifei Kang, Jiacheng Zhu, Kenji Watanabe, Takashi Taniguchi, Debanjan Chowdhury, Liang Fu, Jie Shan and Kin Fai Mak

Directed assembly of layered perovskite heterostructures as single crystals pp. 355-359

Michael L. Aubrey, Abraham Saldivar Valdes, Marina R. Filip, Bridget A. Connor, Kurt P. Lindquist, Jeffrey B. Neaton and Hemamala I. Karunadasa

Environmental performance of blue foods pp. 360-365

Jessica A. Gephart, Patrik J. G. Henriksson, Robert W. R. Parker, Alon Shepon, Kelvin D. Gorospe, Kristina Bergman, Gidon Eshel, Christopher D. Golden, Benjamin S. Halpern, Sara Hornborg, Malin Jonell, Marc Metian, Kathleen Mifflin, Richard Newton, Peter Tyedmers, Wenbo Zhang, Friederike Ziegler and Max Troell

Vast CO2 release from Australian fires in 2019–2020 constrained by satellite pp. 366-369

Ivar R. Velde, Guido R. Werf, Sander Houweling, Joannes D. Maasakkers, Tobias Borsdorff, Jochen Landgraf, Paul Tol, Tim A. Kempen, Richard Hees, Ruud Hoogeveen, J. Pepijn Veefkind and Ilse Aben

Widespread phytoplankton blooms triggered by 2019–2020 Australian wildfires pp. 370-375

Weiyi Tang, Joan Llort, Jakob Weis, Morgane M. G. Perron, Sara Basart, Zuchuan Li, Shubha Sathyendranath, Thomas Jackson, Estrella Sanz Rodriguez, Bernadette C. Proemse, Andrew R. Bowie, Christina Schallenberg, Peter G. Strutton, Richard Matear and Nicolas Cassar

Multiple hominin dispersals into Southwest Asia over the past 400,000 years pp. 376-380

Huw S. Groucutt, Tom S. White, Eleanor M. L. Scerri, Eric Andrieux, Richard Clark-Wilson, Paul S. Breeze, Simon J. Armitage, Mathew Stewart, Nick Drake, Julien Louys, Gilbert J. Price, Mathieu Duval, Ash Parton, Ian Candy, W. Christopher Carleton, Ceri Shipton, Richard P. Jennings, Muhammad Zahir, James Blinkhorn, Simon Blockley, Abdulaziz Al-Omari, Abdullah M. Alsharekh and Michael D. Petraglia

The mutational landscape of human somatic and germline cells pp. 381-386

Luiza Moore, Alex Cagan, Tim H. H. Coorens, Matthew D. C. Neville, Rashesh Sanghvi, Mathijs A. Sanders, Thomas R. W. Oliver, Daniel Leongamornlert, Peter Ellis, Ayesha Noorani, Thomas J. Mitchell, Timothy M. Butler, Yvette Hooks, Anne Y. Warren, Mette Jorgensen, Kevin J. Dawson, Andrew Menzies, Laura O’Neill, Calli Latimer, Mabel Teng, Ruben Boxtel, Christine A. Iacobuzio-Donahue, Inigo Martincorena, Rakesh Heer, Peter J. Campbell, Rebecca C. Fitzgerald, Michael R. Stratton and Raheleh Rahbari

Extensive phylogenies of human development inferred from somatic mutations pp. 387-392

Tim H. H. Coorens, Luiza Moore, Philip S. Robinson, Rashesh Sanghvi, Joseph Christopher, James Hewinson, Moritz J. Przybilla, Andrew R. J. Lawson, Michael Spencer Chapman, Alex Cagan, Thomas R. W. Oliver, Matthew D. C. Neville, Yvette Hooks, Ayesha Noorani, Thomas J. Mitchell, Rebecca C. Fitzgerald, Peter J. Campbell, Iñigo Martincorena, Raheleh Rahbari and Michael R. Stratton

Clonal dynamics in early human embryogenesis inferred from somatic mutation pp. 393-397

Seongyeol Park, Nanda Maya Mali, Ryul Kim, Jeong-Woo Choi, Junehawk Lee, Joonoh Lim, Jung Min Park, Jung Woo Park, Donghyun Kim, Taewoo Kim, Kijong Yi, June Hyug Choi, Seong Gyu Kwon, Joo Hee Hong, Jeonghwan Youk, Yohan An, Su Yeon Kim, Soo A Oh, Youngoh Kwon, Dongwan Hong, Moonkyu Kim, Dong Sun Kim, Ji Young Park, Ji Won Oh and Young Seok Ju

A body map of somatic mutagenesis in morphologically normal human tissues pp. 398-403

Ruoyan Li, Lin Di, Jie Li, Wenyi Fan, Yachen Liu, Wenjia Guo, Weiling Liu, Lu Liu, Qiong Li, Liping Chen, Yamei Chen, Chuanwang Miao, Hongjin Liu, Yuqian Wang, Yuling Ma, Deshu Xu, Dongxin Lin, Yanyi Huang, Jianbin Wang, Fan Bai and Chen Wu

Behavioural nudges increase COVID-19 vaccinations pp. 404-409

Hengchen Dai, Silvia Saccardo, Maria A. Han, Lily Roh, Naveen Raja, Sitaram Vangala, Hardikkumar Modi, Shital Pandya, Michael Sloyan and Daniel M. Croymans

Neuro-mesenchymal units control ILC2 and obesity via a brain–adipose circuit pp. 410-414

Filipa Cardoso, Roel G. J. Klein Wolterink, Cristina Godinho-Silva, Rita G. Domingues, Hélder Ribeiro, Joaquim Alves da Silva, Inês Mahú, Ana I. Domingos and Henrique Veiga-Fernandes

AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence pp. 415-419

SangJoon Lee, Rajendra Karki, Yaqiu Wang, Lam Nhat Nguyen, Ravi C. Kalathur and Thirumala-Devi Kanneganti

The polar oxy-metabolome reveals the 4-hydroxymandelate CoQ10 synthesis pathway pp. 420-425

Robert S. Banh, Esther S. Kim, Quentin Spillier, Douglas E. Biancur, Keisuke Yamamoto, Albert S. W. Sohn, Guangbin Shi, Drew R. Jones, Alec C. Kimmelman and Michael E. Pacold

RecA finds homologous DNA by reduced dimensionality search pp. 426-429

Jakub Wiktor, Arvid H. Gynnå, Prune Leroy, Jimmy Larsson, Giovanna Coceano, Ilaria Testa and Johan Elf

Structure of Geobacter pili reveals secretory rather than nanowire behaviour pp. 430-434

Yangqi Gu, Vishok Srikanth, Aldo I. Salazar-Morales, Ruchi Jain, J. Patrick O’Brien, Sophia M. Yi, Rajesh Kumar Soni, Fadel A. Samatey, Sibel Ebru Yalcin and Nikhil S. Malvankar

Springboard to science: the institutions that shaped Black researchers’ careers pp. 435-438

Virginia Gewin and David Payne

Breeding the sweetest biofuels in the business pp. 440-440

James Mitchell Crow

2021, volume 597, articles 7875

Author Correction: Mechanisms of BRCA1–BARD1 nucleosome recognition and ubiquitylation pp. E5-E5

Qi Hu, Maria Victoria Botuyan, Debiao Zhao, Gaofeng Cui, Elie Mer and Georges Mer

Author Correction: TP53 loss creates therapeutic vulnerability in colorectal cancer pp. E6-E6

Yunhua Liu, Xinna Zhang, Cecil Han, Guohui Wan, Xingxu Huang, Cristina Ivan, Dahai Jiang, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Pulivarthi H. Rao, Dipen M. Maru, Andreas Pahl, Xiaoming He, Anil K. Sood, Lee M. Ellis, Jan Anderl and Xiongbin Lu

How misconduct helped psychological science to thrive pp. 153-153

Jelte Wicherts

US COVID origins report: researchers pleased with scientific approach pp. 159-160

Amy Maxmen

India’s DNA COVID vaccine is a world first – more are coming pp. 161-162

Smriti Mallapaty

Rogue antibodies involved in almost one-fifth of COVID deaths pp. 162-162

Diana Kwon

US achieves laser-fusion record: what it means for nuclear-weapons research pp. 163-164

Jeff Tollefson

Freak US winters linked to Arctic warming pp. 165-165

Quirin Schiermeier

Kids and COVID: why young immune systems are still on top pp. 166-168

Smriti Mallapaty

Climate science is supporting lawsuits that could help save the world pp. 169-171

Quirin Schiermeier

Dispatches from a world aflame pp. 172-173

Alexandra Witze

Personalized profiles for disease risk must capture all facets of health pp. 175-177

Mark McCarthy and Ewan Birney

Nicaragua: renewed call to defend human rights pp. 178-178

Martin Chalfie, Edouard Brézin and Belita Koiller

Spacefarers, protect our planet from falling debris pp. 178-178

Dipshikha Chakravortty, Saptarshi Basu and K. S. Nandakumar

Waive CRISPR patents to meet food needs in low-income countries pp. 178-178

John van der Oost and Louise O. Fresco

COVID-19: release approved vaccines for trials of new ones pp. 178-178

Melanie Saville

Chronically lonely flies overeat and lose sleep pp. 179-180

Joel D. Levine

Fructose in the diet expands the surface of the gut and promotes nutrient absorption pp. 180-182

Patrícia M. Nunes and Dimitrios Anastasiou

A stem-cell basis for skeletal ageing pp. 182-183

Matthew B. Greenblatt and Shawon Debnath

Ubiquitin protein helps cells to recover from stress pp. 183-184

Titus Franzmann and Simon Alberti

Hybrid light–matter states formed in self-assembling cavities pp. 185-186

Johannes Feist

Interface nano-optics with van der Waals polaritons pp. 187-195

Qing Zhang, Guangwei Hu, Weiliang Ma, Peining Li, Alex Krasnok, Rainer Hillenbrand, Andrea Alù and Cheng-Wei Qiu

A roadmap for the Human Developmental Cell Atlas pp. 196-205

Muzlifah Haniffa, Deanne Taylor, Sten Linnarsson, Bruce J. Aronow, Gary D. Bader, Roger A. Barker, Pablo G. Camara, J. Gray Camp, Alain Chédotal, Andrew Copp, Heather C. Etchevers, Paolo Giacobini, Berthold Göttgens, Guoji Guo, Ania Hupalowska, Kylie R. James, Emily Kirby, Arnold Kriegstein, Joakim Lundeberg, John C. Marioni, Kerstin B. Meyer, Kathy K. Niakan, Mats Nilsson, Bayanne Olabi, Dana Pe’er, Aviv Regev, Jennifer Rood, Orit Rozenblatt-Rosen, Rahul Satija, Sarah A. Teichmann, Barbara Treutlein, Roser Vento-Tormo and Simone Webb

Large metallicity variations in the Galactic interstellar medium pp. 206-208

Annalisa Cia, Edward B. Jenkins, Andrew J. Fox, Cédric Ledoux, Tanita Ramburuth-Hurt, Christina Konstantopoulou, Patrick Petitjean and Jens-Kristian Krogager

High-fidelity laser-free universal control of trapped ion qubits pp. 209-213

R. Srinivas, S. C. Burd, H. M. Knaack, R. T. Sutherland, A. Kwiatkowski, S. Glancy, E. Knill, D. J. Wineland, D. Leibfried, A. C. Wilson, D. T. C. Allcock and D. H. Slichter

Tunable self-assembled Casimir microcavities and polaritons pp. 214-219

Battulga Munkhbat, Adriana Canales, Betül Küçüköz, Denis G. Baranov and Timur O. Shegai

Transmembrane transport in inorganic colloidal cell-mimics pp. 220-224

Zhe Xu, Theodore Hueckel, William T. M. Irvine and Stefano Sacanna

Widespread woody plant use of water stored in bedrock pp. 225-229

Erica L. McCormick, David N. Dralle, W. Jesse Hahm, Alison K. Tune, Logan M. Schmidt, K. Dana Chadwick and Daniella M. Rempe

Unextractable fossil fuels in a 1.5 °C world pp. 230-234

Dan Welsby, James Price, Steve Pye and Paul Ekins

A Triassic stem lepidosaur illuminates the origin of lizard-like reptiles pp. 235-238

Ricardo N. Martínez, Tiago R. Simões, Gabriela Sobral and Sebastián Apesteguía

Chronic social isolation signals starvation and reduces sleep in Drosophila pp. 239-244

Wanhe Li, Zikun Wang, Sheyum Syed, Cheng Lyu, Samantha Lincoln, Jenna O’Neil, Andrew D. Nguyen, Irena Feng and Michael W. Young

Hypothalamic dopamine neurons motivate mating through persistent cAMP signalling pp. 245-249

Stephen X. Zhang, Andrew Lutas, Shang Yang, Adriana Diaz, Hugo Fluhr, Georg Nagel, Shiqiang Gao and Mark L. Andermann

Cells of the human intestinal tract mapped across space and time pp. 250-255

Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts, Aaron Fleming, Emma Dann, Hamish W. King, Vitalii Kleshchevnikov, Monika Dabrowska, Sophie Pritchard, Liam Bolt, Sara F. Vieira, Lira Mamanova, Ni Huang, Francesca Perrone, Issac Goh Kai’En, Steven N. Lisgo, Matilda Katan, Steven Leonard, Thomas R. W. Oliver, C. Elizabeth Hook, Komal Nayak, Lia S. Campos, Cecilia Domínguez Conde, Emily Stephenson, Justin Engelbert, Rachel A. Botting, Krzysztof Polanski, Stijn van Dongen, Minal Patel, Michael D. Morgan, John C. Marioni, Omer Ali Bayraktar, Kerstin B. Meyer, Xiaoling He, Roger A. Barker, Holm H. Uhlig, Krishnaa T. Mahbubani, Kourosh Saeb-Parsy, Matthias Zilbauer, Menna R. Clatworthy, Muzlifah Haniffa, Kylie R. James and Sarah A. Teichmann

Aged skeletal stem cells generate an inflammatory degenerative niche pp. 256-262

Thomas H. Ambrosi, Owen Marecic, Adrian McArdle, Rahul Sinha, Gunsagar S. Gulati, Xinming Tong, Yuting Wang, Holly M. Steininger, Malachia Y. Hoover, Lauren S. Koepke, Matthew P. Murphy, Jan Sokol, Eun Young Seo, Ruth Tevlin, Michael Lopez, Rachel E. Brewer, Shamik Mascharak, Laura Lu, Oyinkansola Ajanaku, Stephanie D. Conley, Jun Seita, Maurizio Morri, Norma F. Neff, Debashis Sahoo, Fan Yang, Irving L. Weissman, Michael T. Longaker and Charles K. F. Chan

Dietary fructose improves intestinal cell survival and nutrient absorption pp. 263-267

Samuel R. Taylor, Shakti Ramsamooj, Roger J. Liang, Alyna Katti, Rita Pozovskiy, Neil Vasan, Seo-Kyoung Hwang, Navid Nahiyaan, Nancy J. Francoeur, Emma M. Schatoff, Jared L. Johnson, Manish A. Shah, Andrew J. Dannenberg, Robert P. Sebra, Lukas E. Dow, Lewis C. Cantley, Kyu Y. Rhee and Marcus D. Goncalves

Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine pp. 268-273

Valerie Oberhardt, Hendrik Luxenburger, Janine Kemming, Isabel Schulien, Kevin Ciminski, Sebastian Giese, Benedikt Csernalabics, Julia Lang-Meli, Iga Janowska, Julian Staniek, Katharina Wild, Kristi Basho, Mircea Stefan Marinescu, Jonas Fuchs, Fernando Topfstedt, Ales Janda, Oezlem Sogukpinar, Hanna Hilger, Katarina Stete, Florian Emmerich, Bertram Bengsch, Cornelius F. Waller, Siegbert Rieg, Sagar, Tobias Boettler, Katharina Zoldan, Georg Kochs, Martin Schwemmle, Marta Rizzi, Robert Thimme, Christoph Neumann-Haefelin and Maike Hofmann

Defining HPV-specific B cell responses in patients with head and neck cancer pp. 274-278

Andreas Wieland, Mihir R. Patel, Maria A. Cardenas, Christiane S. Eberhardt, William H. Hudson, Rebecca C. Obeng, Christopher C. Griffith, Xu Wang, Zhuo G. Chen, Haydn T. Kissick, Nabil F. Saba and Rafi Ahmed

Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer pp. 279-284

Christiane S. Eberhardt, Haydn T. Kissick, Mihir R. Patel, Maria A. Cardenas, Nataliya Prokhnevska, Rebecca C. Obeng, Tahseen H. Nasti, Christopher C. Griffith, Se Jin Im, Xu Wang, Dong M. Shin, Mary Carrington, Zhuo G. Chen, John Sidney, Alessandro Sette, Nabil F. Saba, Andreas Wieland and Rafi Ahmed

Structural basis for piRNA targeting pp. 285-289

Todd A. Anzelon, Saikat Chowdhury, Siobhan M. Hughes, Yao Xiao, Gabriel C. Lander and Ian J. MacRae

Five hundred days between pay cheques: the road I took to revive my career pp. 291-292

Nuwan Bandara

Five keys to writing a reproducible lab protocol pp. 293-294

Monya Baker

Who wants to be a polar bear? pp. 296-296

Amber Dance

2021, volume 597, articles 7874

Author Correction: Commensal-driven immune zonation of the liver promotes host defence pp. E1-E1

Anita Gola, Michael G. Dorrington, Emily Speranza, Claudia Sala, Rochelle M. Shih, Andrea J. Radtke, Harikesh S. Wong, Antonio P. Baptista, Jonathan M. Hernandez, Gastone Castellani, Iain D. C. Fraser and Ronald N. Germain

What makes us tick: lab leaders describe their research philosophies pp. S1-S3

Nikki Forrester

Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice pp. E2-E2

Raoul Gasparo, Mattia Pedotti, Luca Simonelli, Petr Nickl, Frauke Muecksch, Irene Cassaniti, Elena Percivalle, Julio C. C. Lorenzi, Federica Mazzola, Davide Magrì, Tereza Michalcikova, Jan Haviernik, Vaclav Honig, Blanka Mrazkova, Natalie Polakova, Andrea Fortova, Jolana Tureckova, Veronika Iatsiuk, Salvatore Girolamo, Martin Palus, Dagmar Zudova, Petr Bednar, Ivana Bukova, Filippo Bianchini, Dora Mehn, Radim Nencka, Petra Strakova, Oto Pavlis, Jan Rozman, Sabrina Gioria, Josè Camilla Sammartino, Federica Giardina, Stefano Gaiarsa, Qiang Pan-Hammarström, Christopher O. Barnes, Pamela J. Bjorkman, Luigi Calzolai, Antonio Piralla, Fausto Baldanti, Michel C. Nussenzweig, Paul D. Bieniasz, Theodora Hatziioannou, Jan Prochazka, Radislav Sedlacek, Davide F. Robbiani, Daniel Ruzek and Luca Varani

Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans pp. E3-E4

Sanna Gudmundsson, Konrad J. Karczewski, Laurent C. Francioli, Grace Tiao, Beryl B. Cummings, Jessica Alföldi, Qingbo Wang, Ryan L. Collins, Kristen M. Laricchia, Andrea Ganna, Daniel P. Birnbaum, Laura D. Gauthier, Harrison Brand, Matthew Solomonson, Nicholas A. Watts, Daniel Rhodes, Moriel Singer-Berk, Eleina M. England, Eleanor G. Seaby, Jack A. Kosmicki, Raymond K. Walters, Katherine Tashman, Yossi Farjoun, Eric Banks, Timothy Poterba, Arcturus Wang, Cotton Seed, Nicola Whiffin, Jessica X. Chong, Kaitlin E. Samocha, Emma Pierce-Hoffman, Zachary Zappala, Anne H. O’Donnell-Luria, Eric Vallabh Minikel, Ben Weisburd, Monkol Lek, James S. Ware, Christopher Vittal, Irina M. Armean, Louis Bergelson, Kristian Cibulskis, Kristen M. Connolly, Miguel Covarrubias, Stacey Donnelly, Steven Ferriera, Stacey Gabriel, Jeff Gentry, Namrata Gupta, Thibault Jeandet, Diane Kaplan, Christopher Llanwarne, Ruchi Munshi, Sam Novod, Nikelle Petrillo, David Roazen, Valentin Ruano-Rubio, Andrea Saltzman, Molly Schleicher, Jose Soto, Kathleen Tibbetts, Charlotte Tolonen, Gordon Wade, Michael E. Talkowski, Benjamin M. Neale, Mark J. Daly and Daniel G. MacArthur

Demand five precepts to aid social-media watchdogs pp. 9-9

Ethan Zuckerman

Afghanistan’s terrified scientists predict huge research losses pp. 15-16

Smriti Mallapaty

Genetic patterns offer clues to evolution of homosexuality pp. 17-18

Sara Reardon

Home seismometers provide crucial data on Haiti’s quake pp. 18-19

Alexandra Witze

Australia’s cane toads evolved as cannibals with frightening speed pp. 19-20

Max Kozlov

The Venezuelan health-care workers secretly collecting COVID stats pp. 20-21

Luke Taylor

What’s next for lab-grown human embryos? pp. 22-24

Kendall Powell

Witness in US climate-change law suit tells all pp. 25-26

Catherine Higham

Shells, sweat, and the fear of strangers: Books in brief pp. 26-26

Andrew Robinson

Carolyn S. Shoemaker (1929–2021) pp. 27-27

David H. Levy

Food systems: seven priorities to end hunger and protect the planet pp. 28-30

Joachim von Braun, Kaosar Afsana, Louise O. Fresco and Mohamed Hassan

Early-career researchers: choose change, not complicity pp. 31-31

Lucrecia K. Aguilar

Boost for Africa’s research must protect its biodiversity pp. 31-31

Nils Chr. Stenseth and Sebsebe Demissew

In memory of a game-changing haematologist pp. 31-31

Daniel Lucas, Christoph Scheiermann and Andrés Hidalgo

Australian bush fires and fuel loads pp. 31-31

Mark Adams and Mathias Neumann

Benzene rings broken for chemical synthesis pp. 33-34

Mark R. Crimmin

cGAS-like receptors put a sting into the evolution of immune defence pp. 34-35

Cara West and Neal Silverman

Molecular memristors offer a path to ultra-efficient computing pp. 36-37

Matthew J. Marinella and A. Alec Talin

Insights into a receptor that lets insects sense scents pp. 37-39

Emily R. Liman

A brain signal that coordinates thought with metabolism pp. 39-40

Manfred Hallschmid and Jan Born

Measuring the density structure of an accretion hot spot pp. 41-44

C. C. Espaillat, C. E. Robinson, M. M. Romanova, T. Thanathibodee, J. Wendeborn, N. Calvet, M. Reynolds and J. Muzerolle

Emergent hydrodynamics in a strongly interacting dipolar spin ensemble pp. 45-50

C. Zu, F. Machado, B. Ye, S. Choi, B. Kobrin, T. Mittiga, S. Hsieh, P. Bhattacharyya, M. Markham, D. Twitchen, A. Jarmola, D. Budker, C. R. Laumann, J. E. Moore and N. Y. Yao

Decision trees within a molecular memristor pp. 51-56

Sreetosh Goswami, Rajib Pramanick, Abhijeet Patra, Santi Prasad Rath, Martin Foltin, A. Ariando, Damien Thompson, T. Venkatesan, Sreebrata Goswami and R. Stanley Williams

Scalable production of high-performing woven lithium-ion fibre batteries pp. 57-63

Jiqing He, Chenhao Lu, Haibo Jiang, Fei Han, Xiang Shi, Jingxia Wu, Liyuan Wang, Taiqiang Chen, Jiajia Wang, Ye Zhang, Han Yang, Guoqi Zhang, Xuemei Sun, Bingjie Wang, Peining Chen, Yonggang Wang, Yongyao Xia and Huisheng Peng

Cleaving arene rings for acyclic alkenylnitrile synthesis pp. 64-69

Xu Qiu, Yueqian Sang, Hao Wu, Xiao-Song Xue, Zixi Yan, Yachong Wang, Zengrui Cheng, Xiaoyang Wang, Hui Tan, Song Song, Guisheng Zhang, Xiaohui Zhang, K. N. Houk and Ning Jiao

Enantioselective synthesis of ammonium cations pp. 70-76

Mark P. Walsh, Joseph M. Phelps, Marc E. Lennon, Dmitry S. Yufit and Matthew O. Kitching

The contribution of insects to global forest deadwood decomposition pp. 77-81

Sebastian Seibold, Werner Rammer, Torsten Hothorn, Rupert Seidl, Michael D. Ulyshen, Janina Lorz, Marc W. Cadotte, David B. Lindenmayer, Yagya P. Adhikari, Roxana Aragón, Soyeon Bae, Petr Baldrian, Hassan Barimani Varandi, Jos Barlow, Claus Bässler, Jacques Beauchêne, Erika Berenguer, Rodrigo S. Bergamin, Tone Birkemoe, Gergely Boros, Roland Brandl, Hervé Brustel, Philip J. Burton, Yvonne T. Cakpo-Tossou, Jorge Castro, Eugénie Cateau, Tyler P. Cobb, Nina Farwig, Romina D. Fernández, Jennifer Firn, Kee Seng Gan, Grizelle González, Martin M. Gossner, Jan C. Habel, Christian Hébert, Christoph Heibl, Osmo Heikkala, Andreas Hemp, Claudia Hemp, Joakim Hjältén, Stefan Hotes, Jari Kouki, Thibault Lachat, Jie Liu, Yu Liu, Ya-Huang Luo, Damasa M. Macandog, Pablo E. Martina, Sharif A. Mukul, Baatarbileg Nachin, Kurtis Nisbet, John O’Halloran, Anne Oxbrough, Jeev Nath Pandey, Tomáš Pavlíček, Stephen M. Pawson, Jacques S. Rakotondranary, Jean-Baptiste Ramanamanjato, Liana Rossi, Jürgen Schmidl, Mark Schulze, Stephen Seaton, Marisa J. Stone, Nigel E. Stork, Byambagerel Suran, Anne Sverdrup-Thygeson, Simon Thorn, Ganesh Thyagarajan, Timothy J. Wardlaw, Wolfgang W. Weisser, Sungsoo Yoon, Naili Zhang and Jörg Müller

A metabolic function of the hippocampal sharp wave-ripple pp. 82-86

David Tingley, Kathryn McClain, Ekin Kaya, Jordan Carpenter and György Buzsáki

Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche pp. 87-91

David Willnow, Uwe Benary, Anca Margineanu, Maria Lillina Vignola, Fabian Konrath, Igor M. Pongrac, Zahra Karimaddini, Alessandra Vigilante, Jana Wolf and Francesca M. Spagnoli

APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans pp. 92-96

Dimitrios Tsiantoulas, Mahya Eslami, Georg Obermayer, Marc Clement, Diede Smeets, Florian J. Mayer, Máté G. Kiss, Lennart Enders, Juliane Weißer, Laura Göderle, Jordi Lambert, Florian Frommlet, André Mueller, Tim Hendrikx, Maria Ozsvar-Kozma, Florentina Porsch, Laure Willen, Taras Afonyushkin, Jane E. Murphy, Per Fogelstrand, Olivier Donzé, Gerard Pasterkamp, Matthias Hoke, Stefan Kubicek, Helle F. Jørgensen, Nicolas Danchin, Tabassome Simon, Hubert Scharnagl, Winfried März, Jan Borén, Henry Hess, Ziad Mallat, Pascal Schneider and Christoph J. Binder

SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape pp. 97-102

Tyler N. Starr, Nadine Czudnochowski, Zhuoming Liu, Fabrizia Zatta, Young-Jun Park, Amin Addetia, Dora Pinto, Martina Beltramello, Patrick Hernandez, Allison J. Greaney, Roberta Marzi, William G. Glass, Ivy Zhang, Adam S. Dingens, John E. Bowen, M. Alejandra Tortorici, Alexandra C. Walls, Jason A. Wojcechowskyj, Anna Marco, Laura E. Rosen, Jiayi Zhou, Martin Montiel-Ruiz, Hannah Kaiser, Josh R. Dillen, Heather Tucker, Jessica Bassi, Chiara Silacci-Fregni, Michael P. Housley, Julia Iulio, Gloria Lombardo, Maria Agostini, Nicole Sprugasci, Katja Culap, Stefano Jaconi, Marcel Meury, Exequiel Dellota, Rana Abdelnabi, Shi-Yan Caroline Foo, Elisabetta Cameroni, Spencer Stumpf, Tristan I. Croll, Jay C. Nix, Colin Havenar-Daughton, Luca Piccoli, Fabio Benigni, Johan Neyts, Amalio Telenti, Florian A. Lempp, Matteo S. Pizzuto, John D. Chodera, Christy M. Hebner, Herbert W. Virgin, Sean P. J. Whelan, David Veesler, Davide Corti, Jesse D. Bloom and Gyorgy Snell

Broad sarbecovirus neutralization by a human monoclonal antibody pp. 103-108

M. Alejandra Tortorici, Nadine Czudnochowski, Tyler N. Starr, Roberta Marzi, Alexandra C. Walls, Fabrizia Zatta, John E. Bowen, Stefano Jaconi, Julia Iulio, Zhaoqian Wang, Anna Marco, Samantha K. Zepeda, Dora Pinto, Zhuoming Liu, Martina Beltramello, Istvan Bartha, Michael P. Housley, Florian A. Lempp, Laura E. Rosen, Exequiel Dellota, Hannah Kaiser, Martin Montiel-Ruiz, Jiayi Zhou, Amin Addetia, Barbara Guarino, Katja Culap, Nicole Sprugasci, Christian Saliba, Eneida Vetti, Isabella Giacchetto-Sasselli, Chiara Silacci Fregni, Rana Abdelnabi, Shi-Yan Caroline Foo, Colin Havenar-Daughton, Michael A. Schmid, Fabio Benigni, Elisabetta Cameroni, Johan Neyts, Amalio Telenti, Herbert W. Virgin, Sean P. J. Whelan, Gyorgy Snell, Jesse D. Bloom, Davide Corti, David Veesler and Matteo Samuele Pizzuto

cGAS-like receptors sense RNA and control 3′2′-cGAMP signalling in Drosophila pp. 109-113

Kailey M. Slavik, Benjamin R. Morehouse, Adelyn E. Ragucci, Wen Zhou, Xianlong Ai, Yuqiang Chen, Lihua Li, Ziming Wei, Heike Bähre, Martin König, Roland Seifert, Amy S. Y. Lee, Hua Cai, Jean-Luc Imler and Philip J. Kranzusch

Two cGAS-like receptors induce antiviral immunity in Drosophila pp. 114-118

Andreas Holleufer, Kasper Grønbjerg Winther, Hans Henrik Gad, Xianlong Ai, Yuqiang Chen, Lihua Li, Ziming Wei, Huimin Deng, Jiyong Liu, Ninna Ahlmann Frederiksen, Bine Simonsen, Line Lykke Andersen, Karin Kleigrewe, Louise Dalskov, Andreas Pichlmair, Hua Cai, Jean-Luc Imler and Rune Hartmann

A clinically applicable integrative molecular classification of meningiomas pp. 119-125

Farshad Nassiri, Jeff Liu, Vikas Patil, Yasin Mamatjan, Justin Z. Wang, Rupert Hugh-White, Andrew M. Macklin, Shahbaz Khan, Olivia Singh, Shirin Karimi, Rosario I. Corona, Lydia Y. Liu, Caroline Y. Chen, Ankur Chakravarthy, Qingxia Wei, Bharati Mehani, Suganth Suppiah, Andrew Gao, Adriana M. Workewych, Ghazaleh Tabatabai, Paul C. Boutros, Gary D. Bader, Daniel D. Carvalho, Thomas Kislinger, Kenneth Aldape and Gelareh Zadeh

The structural basis of odorant recognition in insect olfactory receptors pp. 126-131

Josefina Mármol, Mackenzie A. Yedlin and Vanessa Ruta

DAXX represents a new type of protein-folding enabler pp. 132-137

Liangqian Huang, Trisha Agrawal, Guixin Zhu, Sixiang Yu, Liming Tao, JiaBei Lin, Ronen Marmorstein, James Shorter and Xiaolu Yang

Gender gap in US patents leads to few inventions that help women pp. 139-140

Sara Reardon

Drowning in the literature? These smart software tools can help pp. 141-142

David Matthews

Using sound to explore events of the Universe pp. 144-144

Davide Castelvecchi