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2013, volume 499, articles 7459

SAR11 viruses and defensive host strains pp. E3-E4

Selina Våge, Julia E. Storesund and T. Frede Thingstad

Giovannoni et al. reply pp. E4-E5

Stephen Giovannoni, Ben Temperton and Yanlin Zhao

China needs workers more than academics pp. 381-381

Qiang Wang

Monsanto drops GM in Europe pp. 387-387

Daniel Cressey

Deadly pig virus slips through US borders pp. 388-388

Beth Mole

Stricter standards sought to curb stem-cell confusion pp. 389-389

Helen Shen

Doubt cast over tiny stem cells pp. 390-390

Alison Abbott

Cyclotrons come full circle pp. 391-392

Eugenie Samuel Reich

China’s cordgrass plan is ‘overkill’ pp. 392-393

Jane Qiu

Antibiotic resistance: The last resort pp. 394-396

Maryn McKenna

MRSA: Farming up trouble pp. 398-400

Beth Mole

Vast costs of Arctic change pp. 401-403

Gail Whiteman, Chris Hope and Peter Wadhams

Evolutionary biology: Rare bird of evolution pp. 404-405

Ben C. Sheldon

Books in brief pp. 405-405

Barbara Kiser

Cryptozoology: Beastly fakes pp. 406-406

Daniel Cressey

Q&A: Mountain guardian pp. 407-407

Alexandra Witze

Chocolate habits of Nobel prizewinners pp. 409-409

Beatrice A. Golomb

Future food: Politics plague seed banks pp. 409-409

Dave Wood

Future food: Use local knowledge pp. 409-409

Selena Ahmed and Anna Herforth

Jerome Karle (1918–2013) pp. 410-410

Wayne A. Hendrickson

Pathways to human adaptation pp. 412-413

David A. Steinhauer

Dark and heavy pp. 413-414

Christoph Becker

Tumour stem cells in bone pp. 414-416

Mone Zaidi and Simón Méndez-Ferrer

How to catch a galactic wind pp. 416-417

Mark Westmoquette

Meet the B family pp. 417-418

Patrick M. Sexton and Denise Wootten

Van der Waals heterostructures pp. 419-425

A. K. Geim and I. V. Grigorieva

Heavy solitons in a fermionic superfluid pp. 426-430

Tarik Yefsah, Ariel T. Sommer, Mark J. H. Ku, Lawrence W. Cheuk, Wenjie Ji, Waseem S. Bakr and Martin W. Zwierlein

Insights into the phylogeny and coding potential of microbial dark matter pp. 431-437

Christian Rinke, Patrick Schwientek, Alexander Sczyrba, Natalia N. Ivanova, Iain J. Anderson, Jan-Fang Cheng, Aaron Darling, Stephanie Malfatti, Brandon K. Swan, Esther A. Gies, Jeremy A. Dodsworth, Brian P. Hedlund, George Tsiamis, Stefan M. Sievert, Wen-Tso Liu, Jonathan A. Eisen, Steven J. Hallam, Nikos C. Kyrpides, Ramunas Stepanauskas, Edward M. Rubin, Philip Hugenholtz and Tanja Woyke

Structure of class B GPCR corticotropin-releasing factor receptor 1 pp. 438-443

Kaspar Hollenstein, James Kean, Andrea Bortolato, Robert K. Y. Cheng, Andrew S. Doré, Ali Jazayeri, Robert M. Cooke, Malcolm Weir and Fiona H. Marshall

Structure of the human glucagon class B G-protein-coupled receptor pp. 444-449

Fai Yiu Siu, Min He, Chris de Graaf, Gye Won Han, Dehua Yang, Zhiyun Zhang, Caihong Zhou, Qingping Xu, Daniel Wacker, Jeremiah S. Joseph, Wei Liu, Jesper Lau, Vadim Cherezov, Vsevolod Katritch, Ming-Wei Wang and Raymond C. Stevens

Suppression of star formation in the galaxy NGC 253 by a starburst-driven molecular wind pp. 450-453

Alberto D. Bolatto, Steven R. Warren, Adam K. Leroy, Fabian Walter, Sylvain Veilleux, Eve C. Ostriker, Jürgen Ott, Martin Zwaan, David B. Fisher, Axel Weiss, Erik Rosolowsky and Jacqueline Hodge

Solving the Martian meteorite age conundrum using micro-baddeleyite and launch-generated zircon pp. 454-457

D. E. Moser, K. R. Chamberlain, K. T. Tait, A. K. Schmitt, J. R. Darling, I. R. Barker and B. C. Hyde

An ultra-lightweight design for imperceptible plastic electronics pp. 458-463

Martin Kaltenbrunner, Tsuyoshi Sekitani, Jonathan Reeder, Tomoyuki Yokota, Kazunori Kuribara, Takeyoshi Tokuhara, Michael Drack, Reinhard Schwödiauer, Ingrid Graz, Simona Bauer-Gogonea, Siegfried Bauer and Takao Someya

North Atlantic Ocean control on surface heat flux on multidecadal timescales pp. 464-467

Sergey K. Gulev, Mojib Latif, Noel Keenlyside, Wonsun Park and Klaus Peter Koltermann

High frequency of functional extinctions in ecological networks pp. 468-470

Torbjörn Säterberg, Stefan Sellman and Bo Ebenman

Great ape genetic diversity and population history pp. 471-475

Javier Prado-Martinez, Peter H. Sudmant, Jeffrey M. Kidd, Heng Li, Joanna L. Kelley, Belen Lorente-Galdos, Krishna R. Veeramah, August E. Woerner, Timothy D. O’Connor, Gabriel Santpere, Alexander Cagan, Christoph Theunert, Ferran Casals, Hafid Laayouni, Kasper Munch, Asger Hobolth, Anders E. Halager, Maika Malig, Jessica Hernandez-Rodriguez, Irene Hernando-Herraez, Kay Prüfer, Marc Pybus, Laurel Johnstone, Michael Lachmann, Can Alkan, Dorina Twigg, Natalia Petit, Carl Baker, Fereydoun Hormozdiari, Marcos Fernandez-Callejo, Marc Dabad, Michael L. Wilson, Laurie Stevison, Cristina Camprubí, Tiago Carvalho, Aurora Ruiz-Herrera, Laura Vives, Marta Mele, Teresa Abello, Ivanela Kondova, Ronald E. Bontrop, Anne Pusey, Felix Lankester, John A. Kiyang, Richard A. Bergl, Elizabeth Lonsdorf, Simon Myers, Mario Ventura, Pascal Gagneux, David Comas, Hans Siegismund, Julie Blanc, Lidia Agueda-Calpena, Marta Gut, Lucinda Fulton, Sarah A. Tishkoff, James C. Mullikin, Richard K. Wilson, Ivo G. Gut, Mary Katherine Gonder, Oliver A. Ryder, Beatrice H. Hahn, Arcadi Navarro, Joshua M. Akey, Jaume Bertranpetit, David Reich, Thomas Mailund, Mikkel H. Schierup, Christina Hvilsom, Aida M. Andrés, Jeffrey D. Wall, Carlos D. Bustamante, Michael F. Hammer, Evan E. Eichler and Tomas Marques-Bonet

Attention enhances synaptic efficacy and the signal-to-noise ratio in neural circuits pp. 476-480

Farran Briggs, George R. Mangun and W. Martin Usrey

Vascularized and functional human liver from an iPSC-derived organ bud transplant pp. 481-484

Takanori Takebe, Keisuke Sekine, Masahiro Enomura, Hiroyuki Koike, Masaki Kimura, Takunori Ogaeri, Ran-Ran Zhang, Yasuharu Ueno, Yun-Wen Zheng, Naoto Koike, Shinsuke Aoyama, Yasuhisa Adachi and Hideki Taniguchi

mTORC1 couples immune signals and metabolic programming to establish Treg-cell function pp. 485-490

Hu Zeng, Kai Yang, Caryn Cloer, Geoffrey Neale, Peter Vogel and Hongbo Chi

Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling pp. 491-495

Wentian Yang, Jianguo Wang, Douglas C. Moore, Haipei Liang, Mark Dooner, Qian Wu, Richard Terek, Qian Chen, Michael G. Ehrlich, Peter J. Quesenberry and Benjamin G. Neel

Receptor binding by an H7N9 influenza virus from humans pp. 496-499

Xiaoli Xiong, Stephen R. Martin, Lesley F. Haire, Stephen A. Wharton, Rodney S. Daniels, Michael S. Bennett, John W. McCauley, Patrick J. Collins, Philip A. Walker, John J. Skehel and Steven J. Gamblin

Biological features of novel avian influenza A (H7N9) virus pp. 500-503

Jianfang Zhou, Dayan Wang, Rongbao Gao, Baihui Zhao, Jingdong Song, Xian Qi, Yanjun Zhang, Yonglin Shi, Lei Yang, Wenfei Zhu, Tian Bai, Kun Qin, Yu Lan, Shumei Zou, Junfeng Guo, Jie Dong, Libo Dong, Ye Zhang, Hejiang Wei, Xiaodan Li, Jian Lu, Liqi Liu, Xiang Zhao, Xiyan Li, Weijuan Huang, Leying Wen, Hong Bo, Li Xin, Yongkun Chen, Cuilin Xu, Yuquan Pei, Yue Yang, Xiaodong Zhang, Shiwen Wang, Zijian Feng, Jun Han, Weizhong Yang, George F. Gao, Guizhen Wu, Dexin Li, Yu Wang and Yuelong Shu

Correction: Corrigendum: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression pp. 504-504

Arun Sreekumar, Laila M. Poisson, Thekkelnaycke M. Rajendiran, Amjad P. Khan, Qi Cao, Jindan Yu, Bharathi Laxman, Rohit Mehra, Robert J. Lonigro, Yong Li, Mukesh K. Nyati, Aarif Ahsan, Shanker Kalyana-Sundaram, Bo Han, Xuhong Cao, Jaeman Byun, Gilbert S. Omenn, Debashis Ghosh, Subramaniam Pennathur, Danny C. Alexander, Alvin Berger, Jeffrey R. Shuster, John T. Wei, Sooryanarayana Varambally, Christopher Beecher and Arul M. Chinnaiyan

Correction: Corrigendum: Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway pp. 504-504

Jaekyoung Son, Costas A. Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M. Perera, Cristina R. Ferrone, Edouard Mullarky, Ng Shyh-Chang, Ya’an Kang, Jason B. Fleming, Nabeel Bardeesy, John M. Asara, Marcia C. Haigis, Ronald A. DePinho, Lewis C. Cantley and Alec C. Kimmelman

Cancer shows strength through diversity pp. 505-508

Caitlin Smith

Biotechnology: Independent streak pp. 509-511

Virginia Gewin

Surrendered human pp. 514-514

Deborah Walker

2013, volume 499, articles 7458

Don’t market stem-cell products ahead of proof pp. 255-255

Paolo Bianco

Asteroid plan looks rocky pp. 261-262

Alexandra Witze

Hunt for mystery GM wheat hots up pp. 262-263

Heidi Ledford

NIH gambles on recycled drugs pp. 263-264

Meredith Wadman

Rinderpest research restarts pp. 264-265

Declan Butler

Fukushima offers real-time ecolab pp. 265-266

Ewen Callaway

Lasers boost space communications pp. 266-267

Devin Powell

Education online: The virtual lab pp. 268-270

M. Mitchell Waldrop

Neuroscience: Solving the brain pp. 272-274

Alison Abbott

Look, then leap pp. 275-277

Michael M. Crow

Online on-ramps pp. 277-278

Hazel Sive and Sanjay Sarma

In retrospect: The Prince pp. 280-281

John Whitfield

Neurophilosophy: My brain and I pp. 282-282

Chris Frith

Genomics: Art of the hypothetical pp. 283-283

Elie Dolgin

Academy reform needs a reality check pp. 284-284

Sergey V. Razin and Yegor S. Vassetzky

Two more red flags for suspect work pp. 284-284

Jason E. McDermott

Promotional tactics corrupt research pp. 284-284

Michael Kelly

Don't do big-data science backwards pp. 284-284

David B. Lindenmayer and Gene E. Likens

Andreev states taken to the next level pp. 286-287

Simon Gustavsson and William D. Oliver

Carbon dioxide and water use in forests pp. 287-289

Belinda Medlyn and Martin De Kauwe

A three-state balancing act pp. 289-290

Ronald Micura

Let it B pp. 290-291

Yosef Nir

Calculated treatment pp. 291-292

Natalia L. Komarova and C. Richard Boland

Toxins in tandem pp. 293-293

C. Erec Stebbins

Ultrasensitive fluorescent proteins for imaging neuronal activity pp. 295-300

Tsai-Wen Chen, Trevor J. Wardill, Yi Sun, Stefan R. Pulver, Sabine L. Renninger, Amy Baohan, Eric R. Schreiter, Rex A. Kerr, Michael B. Orger, Vivek Jayaraman, Loren L. Looger, Karel Svoboda and Douglas S. Kim

Myomaker is a membrane activator of myoblast fusion and muscle formation pp. 301-305

Douglas P. Millay, Jason R. O’Rourke, Lillian B. Sutherland, Svetlana Bezprozvannaya, John M. Shelton, Rhonda Bassel-Duby and Eric N. Olson

LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling pp. 306-311

Xiaomeng Wang, Sabu Abraham, Jenny A. G. McKenzie, Natasha Jeffs, Matthew Swire, Vineeta B. Tripathi, Ulrich F. O. Luhmann, Clemens A. K. Lange, Zhenhua Zhai, Helen M. Arthur, James W. B. Bainbridge, Stephen E. Moss and John Greenwood

Exciting Andreev pairs in a superconducting atomic contact pp. 312-315

L. Bretheau, Ç. Ö. Girit, H. Pothier, D. Esteve and C. Urbina

Sequential deposition as a route to high-performance perovskite-sensitized solar cells pp. 316-319

Julian Burschka, Norman Pellet, Soo-Jin Moon, Robin Humphry-Baker, Peng Gao, Mohammad K. Nazeeruddin and Michael Grätzel

Elucidation of the Fe(iv)=O intermediate in the catalytic cycle of the halogenase SyrB2 pp. 320-323

Shaun D. Wong, Martin Srnec, Megan L. Matthews, Lei V. Liu, Yeonju Kwak, Kiyoung Park, Caleb B. Bell, E. Ercan Alp, Jiyong Zhao, Yoshitaka Yoda, Shinji Kitao, Makoto Seto, Carsten Krebs, J. Martin Bollinger and Edward I. Solomon

Increase in forest water-use efficiency as atmospheric carbon dioxide concentrations rise pp. 324-327

Trevor F. Keenan, David Y. Hollinger, Gil Bohrer, Danilo Dragoni, J. William Munger, Hans Peter Schmid and Andrew D. Richardson

Ratios of S, Se and Te in the silicate Earth require a volatile-rich late veneer pp. 328-331

Zaicong Wang and Harry Becker

Reversal of an ancient sex chromosome to an autosome in Drosophila pp. 332-335

Beatriz Vicoso and Doris Bachtrog

Behaviour-dependent recruitment of long-range projection neurons in somatosensory cortex pp. 336-340

Jerry L. Chen, Stefano Carta, Joana Soldado-Magraner, Bernard L. Schneider and Fritjof Helmchen

Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR pp. 341-345

Daniel H. Ebert, Harrison W. Gabel, Nathaniel D. Robinson, Nathaniel R. Kastan, Linda S. Hu, Sonia Cohen, Adrija J. Navarro, Matthew J. Lyst, Robert Ekiert, Adrian P. Bird and Michael E. Greenberg

High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat pp. 346-349

Xiao Tian, Jorge Azpurua, Christopher Hine, Amita Vaidya, Max Myakishev-Rempel, Julia Ablaeva, Zhiyong Mao, Eviatar Nevo, Vera Gorbunova and Andrei Seluanov

Structure and function of the Salmonella Typhi chimaeric A2B5 typhoid toxin pp. 350-354

Jeongmin Song, Xiang Gao and Jorge E. Galán

Three-state mechanism couples ligand and temperature sensing in riboswitches pp. 355-359

Anke Reining, Senada Nozinovic, Kai Schlepckow, Florian Buhr, Boris Fürtig and Harald Schwalbe

Promoter directionality is controlled by U1 snRNP and polyadenylation signals pp. 360-363

Albert E. Almada, Xuebing Wu, Andrea J. Kriz, Christopher B. Burge and Phillip A. Sharp

Carbon catabolite repression of the maltose transporter revealed by X-ray crystallography pp. 364-368

Shanshuang Chen, Michael L. Oldham, Amy L. Davidson and Jue Chen

Online learning: How to make a MOOC pp. 369-371

Sarah Kellogg

Turning point: Thijn Brummelkamp pp. 371-371

Roberta Kwok

Think big pp. 374-374

Gregory Benford

2013, volume 499, articles 7457

Zheng et al. reply pp. E1-E2

Jingmai O’Connor, Xiaoting Zheng and Zhonghe Zhou

Can ovarian follicles fossilize? pp. E1-E1

Gerald Mayr and Albrecht Manegold

A slippery slope to human germline modification pp. 127-127

Marcy Darnovsky

Teething troubles at huge telescope pp. 133-134

Alexandra Witze

Deal boosts blind’s access to texts pp. 134-135

Declan Butler

Imaging hits noise barrier pp. 135-136

Eugenie Samuel Reich

Outcry over plans for ‘Japanese NIH’ pp. 136-137

Ichiko Fuyuno

US research firms put under pressure to sell pp. 137-138

Eugenie Samuel Reich

Climate change: The forecast for 2018 is cloudy with record heat pp. 139-141

Jeff Tollefson

Science media: Centre of attention pp. 142-144

Ewen Callaway

The smart-grid solution pp. 145-147

Massoud Amin

Summer books pp. 150-153

David Katz, Jim Bell, Monique Borgerhoff Mulder, Cyrus C. M. Mody, Henry Nicholls, Oren Harman, Mike Davis, Suzanne Alonzo, Stuart Pimm, Calestous Juma, Virginia Valian, Patricia Fara, Jennifer Rampling, Richard Van Noorden, Barbara Kiser, Alison Abbott, Mary Abraham, Tanguy Chouard, Meredith Wadman, Ewen Callaway, Joanne Baker, Roseann Campbell, Dinah Loon, Davide Castelvecchi and María Luisa Ávila-Jiménez

Don't glorify Arab astronomy pp. 154-154

Carlo Rovelli

Shale gas: Pollution fears in China pp. 154-154

Hong Yang, Roger J. Flower and Julian R. Thompson

Shale gas: Surface water also at risk pp. 154-154

Guangming Zeng, Ming Chen and Zhuotong Zeng

Badger-cull statistics carry uncertainty pp. 154-154

Christl Donnelly

Molecular secrets of a parasite pp. 156-157

Swaminathan Venkatesh, Jerry L. Workman, Mats Wahlgren and Maria Teresa Bejarano

A third way to rift continents pp. 157-159

W. Roger Buck

Trapping the light fantastic pp. 159-160

A. Douglas Stone

A holistic approach to climate targets pp. 160-161

Joeri Rogelj

Lipid switches and traffic control pp. 161-162

Sandra L. Schmid and Marcel Mettlen

Oversimplifying quantum factoring pp. 163-165

John A. Smolin, Graeme Smith and Alexander Vargo

Temporal regulation of EGF signalling networks by the scaffold protein Shc1 pp. 166-171

Yong Zheng, Cunjie Zhang, David R. Croucher, Mohamed A. Soliman, Nicole St-Denis, Adrian Pasculescu, Lorne Taylor, Stephen A. Tate, W. Rod Hardy, Karen Colwill, Anna Yue Dai, Rick Bagshaw, James W. Dennis, Anne-Claude Gingras, Roger J. Daly and Tony Pawson

A compendium of RNA-binding motifs for decoding gene regulation pp. 172-177

Debashish Ray, Hilal Kazan, Kate B. Cook, Matthew T. Weirauch, Hamed S. Najafabadi, Xiao Li, Serge Gueroussov, Mihai Albu, Hong Zheng, Ally Yang, Hong Na, Manuel Irimia, Leah H. Matzat, Ryan K. Dale, Sarah A. Smith, Christopher A. Yarosh, Seth M. Kelly, Behnam Nabet, Desirea Mecenas, Weimin Li, Rakesh S. Laishram, Mei Qiao, Howard D. Lipshitz, Fabio Piano, Anita H. Corbett, Russ P. Carstens, Brendan J. Frey, Richard A. Anderson, Kristen W. Lynch, Luiz O. F. Penalva, Elissa P. Lei, Andrew G. Fraser, Benjamin J. Blencowe, Quaid D. Morris and Timothy R. Hughes

The Mycobacterium tuberculosis regulatory network and hypoxia pp. 178-183

James E. Galagan, Kyle Minch, Matthew Peterson, Anna Lyubetskaya, Elham Azizi, Linsday Sweet, Antonio Gomes, Tige Rustad, Gregory Dolganov, Irina Glotova, Thomas Abeel, Chris Mahwinney, Adam D. Kennedy, René Allard, William Brabant, Andrew Krueger, Suma Jaini, Brent Honda, Wen-Han Yu, Mark J. Hickey, Jeremy Zucker, Christopher Garay, Brian Weiner, Peter Sisk, Christian Stolte, Jessica K. Winkler, Yves Van de Peer, Paul Iazzetti, Diogo Camacho, Jonathan Dreyfuss, Yang Liu, Anca Dorhoi, Hans-Joachim Mollenkopf, Paul Drogaris, Julie Lamontagne, Yiyong Zhou, Julie Piquenot, Sang Tae Park, Sahadevan Raman, Stefan H. E. Kaufmann, Robert P. Mohney, Daniel Chelsky, D. Branch Moody, David R. Sherman and Gary K. Schoolnik

Formation of sharp eccentric rings in debris disks with gas but without planets pp. 184-187

W. Lyra and M. Kuchner

Observation of trapped light within the radiation continuum pp. 188-191

Chia Wei Hsu, Bo Zhen, Jeongwon Lee, Song-Liang Chua, Steven G. Johnson, John D. Joannopoulos and Marin Soljačić

Metal-free oxidation of aromatic carbon–hydrogen bonds through a reverse-rebound mechanism pp. 192-196

Changxia Yuan, Yong Liang, Taylor Hernandez, Adrian Berriochoa, Kendall N. Houk and Dionicio Siegel

Allowable carbon emissions lowered by multiple climate targets pp. 197-201

Marco Steinacher, Fortunat Joos and Thomas F. Stocker

Characterization and implications of intradecadal variations in length of day pp. 202-204

R. Holme and O. de Viron

Gene expression in the deep biosphere pp. 205-208

William D. Orsi, Virginia P. Edgcomb, Glenn D. Christman and Jennifer F. Biddle

Pan genome of the phytoplankton Emiliania underpins its global distribution pp. 209-213

Betsy A. Read, Jessica Kegel, Mary J. Klute, Alan Kuo, Stephane C. Lefebvre, Florian Maumus, Christoph Mayer, John Miller, Adam Monier, Asaf Salamov, Jeremy Young, Maria Aguilar, Jean-Michel Claverie, Stephan Frickenhaus, Karina Gonzalez, Emily K. Herman, Yao-Cheng Lin, Johnathan Napier, Hiroyuki Ogata, Analissa F. Sarno, Jeremy Shmutz, Declan Schroeder, Colomban de Vargas, Frederic Verret, Peter von Dassow, Klaus Valentin, Yves Van de Peer, Glen Wheeler, Joel B. Dacks, Charles F. Delwiche, Sonya T. Dyhrman, Gernot Glöckner, Uwe John, Thomas Richards, Alexandra Z. Worden, Xiaoyu Zhang and Igor V. Grigoriev

Mutational heterogeneity in cancer and the search for new cancer-associated genes pp. 214-218

Michael S. Lawrence, Petar Stojanov, Paz Polak, Gregory V. Kryukov, Kristian Cibulskis, Andrey Sivachenko, Scott L. Carter, Chip Stewart, Craig H. Mermel, Steven A. Roberts, Adam Kiezun, Peter S. Hammerman, Aaron McKenna, Yotam Drier, Lihua Zou, Alex H. Ramos, Trevor J. Pugh, Nicolas Stransky, Elena Helman, Jaegil Kim, Carrie Sougnez, Lauren Ambrogio, Elizabeth Nickerson, Erica Shefler, Maria L. Cortés, Daniel Auclair, Gordon Saksena, Douglas Voet, Michael Noble, Daniel DiCara, Pei Lin, Lee Lichtenstein, David I. Heiman, Timothy Fennell, Marcin Imielinski, Bryan Hernandez, Eran Hodis, Sylvan Baca, Austin M. Dulak, Jens Lohr, Dan-Avi Landau, Catherine J. Wu, Jorge Melendez-Zajgla, Alfredo Hidalgo-Miranda, Amnon Koren, Steven A. McCarroll, Jaume Mora, Ryan S. Lee, Brian Crompton, Robert Onofrio, Melissa Parkin, Wendy Winckler, Kristin Ardlie, Stacey B. Gabriel, Charles W. M. Roberts, Jaclyn A. Biegel, Kimberly Stegmaier, Adam J. Bass, Levi A. Garraway, Matthew Meyerson, Todd R. Golub, Dmitry A. Gordenin, Shamil Sunyaev, Eric S. Lander and Gad Getz

Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome pp. 219-222

Sheetal R. Modi, Henry H. Lee, Catherine S. Spina and James J. Collins

PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum pp. 223-227

Lubin Jiang, Jianbing Mu, Qingfeng Zhang, Ting Ni, Prakash Srinivasan, Kempaiah Rayavara, Wenjing Yang, Louise Turner, Thomas Lavstsen, Thor G. Theander, Weiqun Peng, Guiying Wei, Qingqing Jing, Yoshiyuki Wakabayashi, Abhisheka Bansal, Yan Luo, José M. C. Ribeiro, Artur Scherf, L. Aravind, Jun Zhu, Keji Zhao and Louis H. Miller

Wnt activation in nail epithelium couples nail growth to digit regeneration pp. 228-232

Makoto Takeo, Wei Chin Chou, Qi Sun, Wendy Lee, Piul Rabbani, Cynthia Loomis, M. Mark Taketo and Mayumi Ito

Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate pp. 233-237

York Posor, Marielle Eichhorn-Gruenig, Dmytro Puchkov, Johannes Schöneberg, Alexander Ullrich, André Lampe, Rainer Müller, Sirus Zarbakhsh, Federico Gulluni, Emilio Hirsch, Michael Krauss, Carsten Schultz, Jan Schmoranzer, Frank Noé and Volker Haucke

An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry pp. 238-242

Sonia Sharma, Ariel Quintana, Gregory M. Findlay, Marcel Mettlen, Beate Baust, Mohit Jain, Roland Nilsson, Anjana Rao and Patrick G. Hogan

Networking: Real connections pp. 243-245

Amy Maxmen

Music meets science pp. 245-245

Stephane Detournay

All that remains pp. 248-248

Shane D. Rhinewald

2013, volume 499, articles 7456

Biology must develop its own big-data systems pp. 7-7

John Boyle

EU debates U-turn on biofuels policy pp. 13-14

Richard Van Noorden

China gears up to tackle tainted water pp. 14-15

Jiao Li

Evolution makes the grade pp. 15-16

Lauren Morello

Bioengineers look beyond patents pp. 16-17

Heidi Ledford

US Senate backs immigration plan pp. 17-18

Helen Shen

European deal cuts red tape pp. 18-19

Quirin Schiermeier

Tissue engineering: How to build a heart pp. 20-22

Brendan Maher

Feeding the future pp. 23-24

Susan McCouch, Gregory J. Baute, James Bradeen, Paula Bramel, Peter K. Bretting, Edward Buckler, John M. Burke, David Charest, Sylvie Cloutier, Glenn Cole, Hannes Dempewolf, Michael Dingkuhn, Catherine Feuillet, Paul Gepts, Dario Grattapaglia, Luigi Guarino, Scott Jackson, Sandra Knapp, Peter Langridge, Amy Lawton-Rauh, Qui Lijua, Charlotte Lusty, Todd Michael, Sean Myles, Ken Naito, Randall L. Nelson, Reno Pontarollo, Christopher M. Richards, Loren Rieseberg, Jeffrey Ross-Ibarra, Steve Rounsley, Ruaraidh Sackville Hamilton, Ulrich Schurr, Nils Stein, Norihiko Tomooka, Esther van der Knaap, David van Tassel, Jane Toll, Jose Valls, Rajeev K. Varshney, Judson Ward, Robbie Waugh, Peter Wenzl and Daniel Zamir

Environmental science: Hymn to fading stars pp. 26-27

Tim Radford

Books in brief pp. 27-27

Barbara Kiser

Arts: Think beyond pp. 28-28

Joanne Baker

US patent rulings will fuel invention pp. 29-29

Harry Ostrer

Will China expand on its carbon trading? pp. 29-29

Xi Liang, Francisco Ascui and David Reiner

Protection for trade of precious rosewood pp. 29-29

Meredith A. Barrett, Jason L. Brown and Anne D. Yoder

Identical twins don't share fingerprints pp. 29-29

John R. Vanderkolk

Latin America should ditch impact factors pp. 29-29

Adrian Monjeau, Jaime R. Rau and Christopher B. Anderson

Heinrich Rohrer (1933–2013) pp. 30-30

Christoph Gerber

The cost of children pp. 32-33

Ruth Mace

The robustness of planet formation pp. 33-34

William F. Welsh

Towards a million-year-old genome pp. 34-35

Craig D. Millar and David M. Lambert

Mutations close in on gene regulation pp. 35-36

Stein Aerts and Jan Cools

Hot and deep pp. 37-37

Andrew Mitchinson

An acidic link pp. 37-38

Suzanne Devkota and Peter. J. Turnbaugh

Sensing when it's time for sex pp. 38-39

Leann Tilley and Malcolm McConville

Enzymes activated by synthetic components pp. 40-41

Ryan D. Bethel and Marcetta Y. Darensbourg

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark pp. 50-54

Amélie Fradet-Turcotte, Marella D. Canny, Cristina Escribano-Díaz, Alexandre Orthwein, Charles C. Y. Leung, Hao Huang, Marie-Claude Landry, Julianne Kitevski-LeBlanc, Sylvie M. Noordermeer, Frank Sicheri and Daniel Durocher

The same frequency of planets inside and outside open clusters of stars pp. 55-58

Søren Meibom, Guillermo Torres, Francois Fressin, David W. Latham, Jason F. Rowe, David R. Ciardi, Steven T. Bryson, Leslie A. Rogers, Christopher E. Henze, Kenneth Janes, Sydney A. Barnes, Geoffrey W. Marcy, Howard Isaacson, Debra A. Fischer, Steve B. Howell, Elliott P. Horch, Jon M. Jenkins, Simon C. Schuler and Justin Crepp

Global resurfacing of Mercury 4.0–4.1 billion years ago by heavy bombardment and volcanism pp. 59-61

Simone Marchi, Clark R. Chapman, Caleb I. Fassett, James W. Head, W. F. Bottke and Robert G. Strom

Reduction of the radiative decay of atomic coherence in squeezed vacuum pp. 62-65

K. W. Murch, S. J. Weber, K. M. Beck, E. Ginossar and I. Siddiqi

Biomimetic assembly and activation of [FeFe]-hydrogenases pp. 66-69

G. Berggren, A. Adamska, C. Lambertz, T. R. Simmons, J. Esselborn, M. Atta, S. Gambarelli, J.-M. Mouesca, E. Reijerse, W. Lubitz, T. Happe, V. Artero and M. Fontecave

Melting during late-stage rifting in Afar is hot and deep pp. 70-73

D. J. Ferguson, J. Maclennan, I. D. Bastow, D. M. Pyle, S. M. Jones, D. Keir, J. D. Blundy, T. Plank and G. Yirgu

Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse pp. 74-78

Ludovic Orlando, Aurélien Ginolhac, Guojie Zhang, Duane Froese, Anders Albrechtsen, Mathias Stiller, Mikkel Schubert, Enrico Cappellini, Bent Petersen, Ida Moltke, Philip L. F. Johnson, Matteo Fumagalli, Julia T. Vilstrup, Maanasa Raghavan, Thorfinn Korneliussen, Anna-Sapfo Malaspinas, Josef Vogt, Damian Szklarczyk, Christian D. Kelstrup, Jakob Vinther, Andrei Dolocan, Jesper Stenderup, Amhed M. V. Velazquez, James Cahill, Morten Rasmussen, Xiaoli Wang, Jiumeng Min, Grant D. Zazula, Andaine Seguin-Orlando, Cecilie Mortensen, Kim Magnussen, John F. Thompson, Jacobo Weinstock, Kristian Gregersen, Knut H. Røed, Véra Eisenmann, Carl J. Rubin, Donald C. Miller, Douglas F. Antczak, Mads F. Bertelsen, Søren Brunak, Khaled A. S. Al-Rasheid, Oliver Ryder, Leif Andersson, John Mundy, Anders Krogh, M. Thomas P. Gilbert, Kurt Kjær, Thomas Sicheritz-Ponten, Lars Juhl Jensen, Jesper V. Olsen, Michael Hofreiter, Rasmus Nielsen, Beth Shapiro, Jun Wang and Eske Willerslev

Variation and genetic control of protein abundance in humans pp. 79-82

Linfeng Wu, Sophie I. Candille, Yoonha Choi, Dan Xie, Lihua Jiang, Jennifer Li-Pook-Than, Hua Tang and Michael Snyder

A single pair of interneurons commands the Drosophila feeding motor program pp. 83-87

Thomas F. Flood, Shinya Iguchi, Michael Gorczyca, Benjamin White, Kei Ito and Motojiro Yoshihara

High-resolution analysis with novel cell-surface markers identifies routes to iPS cells pp. 88-91

James O’Malley, Stavroula Skylaki, Kumiko A. Iwabuchi, Eleni Chantzoura, Tyson Ruetz, Anna Johnsson, Simon R. Tomlinson, Sten Linnarsson and Keisuke Kaji

ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors pp. 92-96

Lingbo Zhang, Lina Prak, Violeta Rayon-Estrada, Prathapan Thiru, Johan Flygare, Bing Lim and Harvey F. Lodish

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome pp. 97-101

Shin Yoshimoto, Tze Mun Loo, Koji Atarashi, Hiroaki Kanda, Seidai Sato, Seiichi Oyadomari, Yoichiro Iwakura, Kenshiro Oshima, Hidetoshi Morita, Masahira Hattori, Kenya Honda, Yuichi Ishikawa, Eiji Hara and Naoko Ohtani

Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies pp. 102-106

Masaru Kanekiyo, Chih-Jen Wei, Hadi M. Yassine, Patrick M. McTamney, Jeffrey C. Boyington, James R. R. Whittle, Srinivas S. Rao, Wing-Pui Kong, Lingshu Wang and Gary J. Nabel

Structural basis for alternating access of a eukaryotic calcium/proton exchanger pp. 107-110

Andrew B. Waight, Bjørn Panyella Pedersen, Avner Schlessinger, Massimiliano Bonomi, Bryant H. Chau, Zygy Roe-Zurz, Aaron J. Risenmay, Andrej Sali and Robert M. Stroud

Structural basis of histone H2A–H2B recognition by the essential chaperone FACT pp. 111-114

Maria Hondele, Tobias Stuwe, Markus Hassler, Felix Halbach, Andrew Bowman, Elisa T. Zhang, Bianca Nijmeijer, Christiane Kotthoff, Vladimir Rybin, Stefan Amlacher, Ed Hurt and Andreas G. Ladurner

Collaboration: A problem shared pp. 115-117

Cameron Walker

The ostracons of Europa pp. 120-120

Ken Hinckley