An essential passenger with p53

James E. Bradner ()
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James E. Bradner: Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature, 2015, vol. 520, issue 7549, 626-627

Abstract: Deletion of the TP53 gene, an event seen in colorectal cancers, often occurs with co-deletion of a gene that encodes an enzyme subunit governing gene transcription. This creates a vulnerability ripe for therapeutic development. See Letter p.697

Date: 2015
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DOI: 10.1038/nature14390

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