The deuterostome context of chordate origins

Christopher J. Lowe (), D. Nathaniel Clarke, Daniel M. Medeiros, Daniel S. Rokhsar and John Gerhart
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Christopher J. Lowe: Hopkins Marine Station, Stanford University
D. Nathaniel Clarke: Hopkins Marine Station, Stanford University
Daniel M. Medeiros: University of Colorado
Daniel S. Rokhsar: Berkeley 142 Life Sciences Addition 3200
John Gerhart: Berkeley 142 Life Sciences Addition 3200

Nature, 2015, vol. 520, issue 7548, 456-465

Abstract: Abstract Our understanding of vertebrate origins is powerfully informed by comparative morphology, embryology and genomics of chordates, hemichordates and echinoderms, which together make up the deuterostome clade. Striking body-plan differences among these phyla have historically hindered the identification of ancestral morphological features, but recent progress in molecular genetics and embryology has revealed deep similarities in body-axis formation and organization across deuterostomes, at stages before morphological differences develop. These developmental genetic features, along with robust support of pharyngeal gill slits as a shared deuterostome character, provide the foundation for the emergence of chordates.

Date: 2015
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DOI: 10.1038/nature14434

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