Distinct relationships of parietal and prefrontal cortices to evidence accumulation

Timothy D. Hanks, Charles D. Kopec, Bingni W. Brunton, Chunyu A. Duan, Jeffrey C. Erlich and Carlos D. Brody ()
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Timothy D. Hanks: Princeton Neuroscience Institute, Princeton University
Charles D. Kopec: Princeton Neuroscience Institute, Princeton University
Bingni W. Brunton: Princeton Neuroscience Institute, Princeton University
Chunyu A. Duan: Princeton Neuroscience Institute, Princeton University
Jeffrey C. Erlich: Princeton Neuroscience Institute, Princeton University
Carlos D. Brody: Princeton Neuroscience Institute, Princeton University

Nature, 2015, vol. 520, issue 7546, 220-223

Abstract: A method to measure the precise relationship between neuronal firing rates and the representation of accumulated evidence is described; results in the parietal and prefrontal cortex of rats, together with transient optogenetic inactivation of the prefrontal cortex, challenge the prevailing view that the prefrontal cortex is part of the neural circuit for accumulating evidence, and suggest that neurons in parietal and prefrontal areas have distinct relationships to evidence accumulation in decision-making.

Date: 2015
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DOI: 10.1038/nature14066

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