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2014, volume 513, articles 7519

Mitochondrial Ca2+ uniporter and CaMKII in heart pp. E1-E2

Francesca Fieni, Derrick E. Johnson, Andy Hudmon and Yuriy Kirichok

Joiner et al. reply pp. E3-E3

Mei-ling A. Joiner, Olha M. Koval, Jingdong Li, B. Julie He, Chantal Allamargot, Zhan Gao, Elizabeth D. Luczak, Duane D. Hall, Brian D. Fink, Biyi Chen, Jinying Yang, Steven A. Moore, Thomas D. Scholz, Stefan Strack, Peter J. Mohler, William I. Sivitz, Long-Sheng Song and Mark E. Anderson

Istanbul canal needs environmental study pp. 461-461

Derin Orhon

Brazil warming to ‘green’ policies pp. 467-468

Jeff Tollefson

Chinese science gets mass transformation pp. 468-469

David Cyranoski

Global Ebola response kicks into gear at last pp. 469-469

Declan Butler

Cheap solar cells tempt businesses pp. 470-470

Richard Van Noorden

US vows to combat antibiotic resistance pp. 471-471

Sara Reardon

Drug-safety pilot makes the grade pp. 472-472

Heidi Ledford

Infectious disease: Ebola’s lost ward pp. 474-477

Erika Check Hayden

Renewable energy: Wind power tests the waters pp. 478-480

Gene Russo

Chemistry: Chemical con artists foil drug discovery pp. 481-483

Jonathan Baell and Michael A. Walters

In retrospect: The Courtship Habits of the Great Crested Grebe pp. 484-485

Michael Brooke

Cosmology: A few words on infinity pp. 485-485

Lucy Fortson

Q&A: Violin detective pp. 486-486

Jascha Hoffman

Social change affects Antarctic priorities pp. 487-487

Nick Gales, Phil Trathan and Anthony Worby

Intensive dairy farms becoming greener pp. 487-487

Stephen LeBlanc

Research critics to be properly informed pp. 487-487

Robert B. Eckhardt and Maciej Henneberg

Science should boost well-being, not GDP pp. 487-487

Mark A. de Vries

A fresh look at river flow pp. 490-491

Nicole M. Gasparini

Ribosome revelations pp. 491-492

Nelson B. Olivier

Leaping lizards pp. 492-492

Patrick Goymer

Window on a watery world pp. 493-494

Eliza M. R. Kempton

Statins give bone growth a boost pp. 494-495

Bjorn R. Olsen

How calcium affects oxygen formation pp. 495-496

Davide Lionetti and Theodor Agapie

Towards turbocharged photosynthesis pp. 497-498

G. Dean Price and Susan M. Howitt

A compass for stem-cell differentiation pp. 498-499

Franz-Josef Müller and Jeanne F. Loring

Asian monsoons in a late Eocene greenhouse world pp. 501-506

A. Licht, M. van Cappelle, H. A. Abels, J.-B. Ladant, J. Trabucho-Alexandre, C. France-Lanord, Y. Donnadieu, J. Vandenberghe, T. Rigaudier, C. Lécuyer, D. Terry, R. Adriaens, A. Boura, Z. Guo, Aung Naing Soe, J. Quade, G. Dupont-Nivet and J.-J. Jaeger

Statin treatment rescues FGFR3 skeletal dysplasia phenotypes pp. 507-511

Akihiro Yamashita, Miho Morioka, Hiromi Kishi, Takeshi Kimura, Yasuhito Yahara, Minoru Okada, Kaori Fujita, Hideaki Sawai, Shiro Ikegawa and Noriyuki Tsumaki

Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia pp. 512-516

Monique Dail, Jason Wong, Jessica Lawrence, Daniel O’Connor, Joy Nakitandwe, Shann-Ching Chen, Jin Xu, Leslie B. Lee, Keiko Akagi, Qing Li, Jon C. Aster, Warren S. Pear, James R. Downing, Deepak Sampath and Kevin Shannon

Structural basis for the inhibition of the eukaryotic ribosome pp. 517-522

Nicolas Garreau de Loubresse, Irina Prokhorova, Wolf Holtkamp, Marina V. Rodnina, Gulnara Yusupova and Marat Yusupov

Early turbulent mixing as the origin of chemical homogeneity in open star clusters pp. 523-525

Yi Feng and Mark R. Krumholz

Water vapour absorption in the clear atmosphere of a Neptune-sized exoplanet pp. 526-529

Jonathan Fraine, Drake Deming, Bjorn Benneke, Heather Knutson, Andrés Jordán, Néstor Espinoza, Nikku Madhusudhan, Ashlee Wilkins and Kamen Todorov

Placing an upper limit on cryptic marine sulphur cycling pp. 530-533

D. T. Johnston, B. C. Gill, A. Masterson, E. Beirne, K. L. Casciotti, A. N. Knapp and W. Berelson

Flow in bedrock canyons pp. 534-537

Jeremy G. Venditti, Colin D. Rennie, James Bomhof, Ryan W. Bradley, Malcolm Little and Michael Church

Brain structure resolves the segmental affinity of anomalocaridid appendages pp. 538-542

Peiyun Cong, Xiaoya Ma, Xianguang Hou, Gregory D. Edgecombe and Nicholas J. Strausfeld

Island biogeography of the Anthropocene pp. 543-546

Matthew R. Helmus, D. Luke Mahler and Jonathan B. Losos

A faster Rubisco with potential to increase photosynthesis in crops pp. 547-550

Myat T. Lin, Alessandro Occhialini, P. John Andralojc, Martin A. J. Parry and Maureen R. Hanson

Glial origin of mesenchymal stem cells in a tooth model system pp. 551-554

Nina Kaukua, Maryam Khatibi Shahidi, Chrysoula Konstantinidou, Vyacheslav Dyachuk, Marketa Kaucka, Alessandro Furlan, Zhengwen An, Longlong Wang, Isabell Hultman, Lars Ährlund-Richter, Hans Blom, Hjalmar Brismar, Natalia Assaife Lopes, Vassilis Pachnis, Ueli Suter, Hans Clevers, Irma Thesleff, Paul Sharpe, Patrik Ernfors, Kaj Fried and Igor Adameyko

Antifungal drug resistance evoked via RNAi-dependent epimutations pp. 555-558

Silvia Calo, Cecelia Shertz-Wall, Soo Chan Lee, Robert J. Bastidas, Francisco E. Nicolás, Joshua A. Granek, Piotr Mieczkowski, Santiago Torres-Martínez, Rosa M. Ruiz-Vázquez, Maria E. Cardenas and Joseph Heitman

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid pp. 559-563

Oscar R. Colegio, Ngoc-Quynh Chu, Alison L. Szabo, Thach Chu, Anne Marie Rhebergen, Vikram Jairam, Nika Cyrus, Carolyn E. Brokowski, Stephanie C. Eisenbarth, Gillian M. Phillips, Gary W. Cline, Andrew J. Phillips and Ruslan Medzhitov

The alarmin IL-33 promotes regulatory T-cell function in the intestine pp. 564-568

Chris Schiering, Thomas Krausgruber, Agnieszka Chomka, Anja Fröhlich, Krista Adelmann, Elizabeth A. Wohlfert, Johanna Pott, Thibault Griseri, Julia Bollrath, Ahmed N. Hegazy, Oliver J. Harrison, Benjamin M. J. Owens, Max Löhning, Yasmine Belkaid, Padraic G. Fallon and Fiona Powrie

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease pp. 569-573

Carolin Anders, Ole Niewoehner, Alessia Duerst and Martin Jinek

Correction: Corrigendum: Quantitative flux analysis reveals folate-dependent NADPH production pp. 574-574

Jing Fan, Jiangbin Ye, Jurre J. Kamphorst, Tomer Shlomi, Craig B. Thompson and Joshua D. Rabinowitz

Correction: Corrigendum: Elephant shark genome provides unique insights into gnathostome evolution pp. 574-574

Byrappa Venkatesh, Alison P. Lee, Vydianathan Ravi, Ashish K. Maurya, Michelle M. Lian, Jeremy B. Swann, Yuko Ohta, Martin F. Flajnik, Yoichi Sutoh, Masanori Kasahara, Shawn Hoon, Vamshidhar Gangu, Scott W. Roy, Manuel Irimia, Vladimir Korzh, Igor Kondrychyn, Zhi Wei Lim, Boon-Hui Tay, Sumanty Tohari, Kiat Whye Kong, Shufen Ho, Belen Lorente-Galdos, Javier Quilez, Tomas Marques-Bonet, Brian J. Raney, Philip W. Ingham, Alice Tay, LaDeana W. Hillier, Patrick Minx, Thomas Boehm, Richard K. Wilson, Sydney Brenner and Wesley C. Warren

Correction: Corrigendum: Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone pp. 574-574

Anjali P. Kusumbe, Saravana K. Ramasamy and Ralf H. Adams

Work–life balance: Kid-friendly digs pp. 575-577

Kendall Powell

Post-apocalyptic conversations with a sidewalk pp. 580-580

Beth Cato

2014, volume 513, articles 7518

GATM gene variants and statin myopathy risk pp. E1-E1

D. F. Carr, A. Alfirevic, R. Johnson, H. Chinoy, T. van Staa and M. Pirmohamed

GATM locus does not replicate in rhabdomyolysis study pp. E1-E3

James S. Floyd, Joshua C. Bis, Jennifer A. Brody, Susan R. Heckbert, Kenneth Rice and Bruce M. Psaty

Mangravite et al. reply pp. E3-E3

Lara M. Mangravite, Barbara E. Engelhardt, Matthew Stephens and Ronald M. Krauss

UN sustainability goals need quantified targets pp. 281-281

Mark Stafford-Smith

High retraction rates raise eyebrows pp. 283-283

Chris Woolston

Japan stem-cell trial stirs envy pp. 287-288

Sara Reardon and David Cyranoski

Lander to aim for comet’s ‘head’ pp. 288-289

Elizabeth Gibney

Climate summit previews push for new global treaty pp. 289-289

Lauren Morello

Sugar substitutes linked to obesity pp. 290-290

Alison Abbott

Indian Mars craft prepares for orbit pp. 291-291

Sanjay Kumar

Cross-bred crops get fit faster pp. 292-292

Natasha Gilbert

Invasive-species control: Bounty hunters pp. 294-295

Hannah Hoag

Diversity: Pride in science pp. 297-300

M Mitchell Waldrop

Medical research: Missing patients pp. 301-302

Esteban G. Burchard

Developing world: Discuss inequality pp. 303-303

P. Wenzel Geissler and Ferdinand Okwaro

Mental health: Tailor informed-consent processes pp. 304-304

Mónica Ruiz-Casares

Collaboration: Strength in diversity pp. 305-305

Richard Freeman and Wei Huang

Genetics: Under the skin pp. 306-307

Nathaniel Comfort

Physics: In thrall to uncertainty pp. 308-309

Jim Baggott

New in paperback pp. 308-308

Emily Banham

Linguistics: The write stuff pp. 309-310

Paul Raeburn

Evolution: Tribes like us pp. 310-311

Tim Lenton

Climate policy: A societal sea change pp. 312-312

Nico Stehr

Internet: Technology and its discontents pp. 313-314

Jaron Lanier

Ebola virus control needs local buy-in pp. 315-315

Gilles Guerrier and Eric D'Ortenzio

Climate models: sunk by humans? pp. 315-315

Robert A. J. Matthews

Climate models: use archaeology record pp. 315-315

Felix Riede

Monitor Brazil's fish sampling closely pp. 315-315

Jean R. S. Vitule, Flávia D. F. Sampaio and André L. B. Magalhães

Shale gas is a fraught solution to emissions pp. 315-315

Hong Yang and Julian R. Thompson

Aristotle's suspect statistical skills pp. 315-315

Taner Z. Sen

Radiating genomes pp. 318-319

Chris D. Jiggins

Catching relativistic electrons pp. 319-320

Zhihuai Zhu and Jennifer E. Hoffman

The evolutionary roots of lethal conflict pp. 321-322

Joan B. Silk

Giant black hole in a stripped galaxy pp. 322-323

Amy E. Reines

Shedding light on a change of mind pp. 323-324

Tomonori Takeuchi and Richard G. M. Morris

Reactivity tamed one bond at a time pp. 324-325

Matthew T. Villaume and Phil S. Baran

Exoplanets pp. 327-327

Leslie Sage

Doppler spectroscopy as a path to the detection of Earth-like planets pp. 328-335

Michel Mayor, Christophe Lovis and Nuno C. Santos

Advances in exoplanet science from Kepler pp. 336-344

Jack J. Lissauer, Rebekah I. Dawson and Scott Tremaine

Highlights in the study of exoplanet atmospheres pp. 345-352

Adam S. Burrows

The role of space telescopes in the characterization of transiting exoplanets pp. 353-357

Artie P. Hatzes

Instrumentation for the detection and characterization of exoplanets pp. 358-366

Francesco Pepe, David Ehrenreich and Michael R. Meyer

Multifunctional organoboron compounds for scalable natural product synthesis pp. 367-374

Fanke Meng, Kevin P. McGrath and Amir H. Hoveyda

The genomic substrate for adaptive radiation in African cichlid fish pp. 375-381

David Brawand, Catherine E. Wagner, Yang I. Li, Milan Malinsky, Irene Keller, Shaohua Fan, Oleg Simakov, Alvin Y. Ng, Zhi Wei Lim, Etienne Bezault, Jason Turner-Maier, Jeremy Johnson, Rosa Alcazar, Hyun Ji Noh, Pamela Russell, Bronwen Aken, Jessica Alföldi, Chris Amemiya, Naoual Azzouzi, Jean-François Baroiller, Frederique Barloy-Hubler, Aaron Berlin, Ryan Bloomquist, Karen L. Carleton, Matthew A. Conte, Helena D'Cotta, Orly Eshel, Leslie Gaffney, Francis Galibert, Hugo F. Gante, Sante Gnerre, Lucie Greuter, Richard Guyon, Natalie S. Haddad, Wilfried Haerty, Rayna M. Harris, Hans A. Hofmann, Thibaut Hourlier, Gideon Hulata, David B. Jaffe, Marcia Lara, Alison P. Lee, Iain MacCallum, Salome Mwaiko, Masato Nikaido, Hidenori Nishihara, Catherine Ozouf-Costaz, David J. Penman, Dariusz Przybylski, Michaelle Rakotomanga, Suzy C. P. Renn, Filipe J. Ribeiro, Micha Ron, Walter Salzburger, Luis Sanchez-Pulido, M. Emilia Santos, Steve Searle, Ted Sharpe, Ross Swofford, Frederick J. Tan, Louise Williams, Sarah Young, Shuangye Yin, Norihiro Okada, Thomas D. Kocher, Eric A. Miska, Eric S. Lander, Byrappa Venkatesh, Russell D. Fernald, Axel Meyer, Chris P. Ponting, J. Todd Streelman, Kerstin Lindblad-Toh, Ole Seehausen and Federica Di Palma

Proteogenomic characterization of human colon and rectal cancer pp. 382-387

Bing Zhang, Jing Wang, Xiaojing Wang, Jing Zhu, Qi Liu, Zhiao Shi, Matthew C. Chambers, Lisa J. Zimmerman, Kent F. Shaddox, Sangtae Kim, Sherri R. Davies, Sean Wang, Pei Wang, Christopher R. Kinsinger, Robert C. Rivers, Henry Rodriguez, R. Reid Townsend, Matthew J. C. Ellis, Steven A. Carr, David L. Tabb, Robert J. Coffey, Robbert J. C. Slebos and Daniel C. Liebler

Molecular architecture and mechanism of the anaphase-promoting complex pp. 388-393

Leifu Chang, Ziguo Zhang, Jing Yang, Stephen H. McLaughlin and David Barford

A massive galaxy in its core formation phase three billion years after the Big Bang pp. 394-397

Erica Nelson, Pieter van Dokkum, Marijn Franx, Gabriel Brammer, Ivelina Momcheva, Natascha Förster Schreiber, Elisabete da Cunha, Linda Tacconi, Rachel Bezanson, Allison Kirkpatrick, Joel Leja, Hans-Walter Rix, Rosalind Skelton, Arjen van der Wel, Katherine Whitaker and Stijn Wuyts

A supermassive black hole in an ultra-compact dwarf galaxy pp. 398-400

Anil C. Seth, Remco van den Bosch, Steffen Mieske, Holger Baumgardt, Mark den Brok, Jay Strader, Nadine Neumayer, Igor Chilingarian, Michael Hilker, Richard McDermid, Lee Spitler, Jean Brodie, Matthias J. Frank and Jonelle L. Walsh

Aridification of the Sahara desert caused by Tethys Sea shrinkage during the Late Miocene pp. 401-404

Zhongshi Zhang, Gilles Ramstein, Mathieu Schuster, Camille Li, Camille Contoux and Qing Yan

Spreading continents kick-started plate tectonics pp. 405-408

Patrice F. Rey, Nicolas Coltice and Nicolas Flament

Ancient human genomes suggest three ancestral populations for present-day Europeans pp. 409-413

Iosif Lazaridis, Nick Patterson, Alissa Mittnik, Gabriel Renaud, Swapan Mallick, Karola Kirsanow, Peter H. Sudmant, Joshua G. Schraiber, Sergi Castellano, Mark Lipson, Bonnie Berger, Christos Economou, Ruth Bollongino, Qiaomei Fu, Kirsten I. Bos, Susanne Nordenfelt, Heng Li, Cesare de Filippo, Kay Prüfer, Susanna Sawyer, Cosimo Posth, Wolfgang Haak, Fredrik Hallgren, Elin Fornander, Nadin Rohland, Dominique Delsate, Michael Francken, Jean-Michel Guinet, Joachim Wahl, George Ayodo, Hamza A. Babiker, Graciela Bailliet, Elena Balanovska, Oleg Balanovsky, Ramiro Barrantes, Gabriel Bedoya, Haim Ben-Ami, Judit Bene, Fouad Berrada, Claudio M. Bravi, Francesca Brisighelli, George B. J. Busby, Francesco Cali, Mikhail Churnosov, David E. C. Cole, Daniel Corach, Larissa Damba, George van Driem, Stanislav Dryomov, Jean-Michel Dugoujon, Sardana A. Fedorova, Irene Gallego Romero, Marina Gubina, Michael Hammer, Brenna M. Henn, Tor Hervig, Ugur Hodoglugil, Aashish R. Jha, Sena Karachanak-Yankova, Rita Khusainova, Elza Khusnutdinova, Rick Kittles, Toomas Kivisild, William Klitz, Vaidutis Kučinskas, Alena Kushniarevich, Leila Laredj, Sergey Litvinov, Theologos Loukidis, Robert W. Mahley, Béla Melegh, Ene Metspalu, Julio Molina, Joanna Mountain, Klemetti Näkkäläjärvi, Desislava Nesheva, Thomas Nyambo, Ludmila Osipova, Jüri Parik, Fedor Platonov, Olga Posukh, Valentino Romano, Francisco Rothhammer, Igor Rudan, Ruslan Ruizbakiev, Hovhannes Sahakyan, Antti Sajantila, Antonio Salas, Elena B. Starikovskaya, Ayele Tarekegn, Draga Toncheva, Shahlo Turdikulova, Ingrida Uktveryte, Olga Utevska, René Vasquez, Mercedes Villena, Mikhail Voevoda, Cheryl A. Winkler, Levon Yepiskoposyan, Pierre Zalloua, Tatijana Zemunik, Alan Cooper, Cristian Capelli, Mark G. Thomas, Andres Ruiz-Linares, Sarah A. Tishkoff, Lalji Singh, Kumarasamy Thangaraj, Richard Villems, David Comas, Rem Sukernik, Mait Metspalu, Matthias Meyer, Evan E. Eichler, Joachim Burger, Montgomery Slatkin, Svante Pääbo, Janet Kelso, David Reich and Johannes Krause

Lethal aggression in Pan is better explained by adaptive strategies than human impacts pp. 414-417

Michael L. Wilson, Christophe Boesch, Barbara Fruth, Takeshi Furuichi, Ian C. Gilby, Chie Hashimoto, Catherine L. Hobaiter, Gottfried Hohmann, Noriko Itoh, Kathelijne Koops, Julia N. Lloyd, Tetsuro Matsuzawa, John C. Mitani, Deus C. Mjungu, David Morgan, Martin N. Muller, Roger Mundry, Michio Nakamura, Jill Pruetz, Anne E. Pusey, Julia Riedel, Crickette Sanz, Anne M. Schel, Nicole Simmons, Michel Waller, David P. Watts, Frances White, Roman M. Wittig, Klaus Zuberbühler and Richard W. Wrangham

Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations pp. 418-421

Ofer Fridman, Amir Goldberg, Irine Ronin, Noam Shoresh and Nathalie Q. Balaban

Genome sequencing of normal cells reveals developmental lineages and mutational processes pp. 422-425

Sam Behjati, Meritxell Huch, Ruben van Boxtel, Wouter Karthaus, David C. Wedge, Asif U. Tamuri, Iñigo Martincorena, Mia Petljak, Ludmil B. Alexandrov, Gunes Gundem, Patrick S. Tarpey, Sophie Roerink, Joyce Blokker, Mark Maddison, Laura Mudie, Ben Robinson, Serena Nik-Zainal, Peter Campbell, Nick Goldman, Marc van de Wetering, Edwin Cuppen, Hans Clevers and Michael R. Stratton

Bidirectional switch of the valence associated with a hippocampal contextual memory engram pp. 426-430

Roger L. Redondo, Joshua Kim, Autumn L. Arons, Steve Ramirez, Xu Liu and Susumu Tonegawa

Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria pp. 431-435

Qingfeng Zhang, T. Nicolai Siegel, Rafael M. Martins, Fei Wang, Jun Cao, Qi Gao, Xiu Cheng, Lubin Jiang, Chung-Chau Hon, Christine Scheidig-Benatar, Hiroshi Sakamoto, Louise Turner, Anja T. R. Jensen, Aurelie Claes, Julien Guizetti, Nicholas A. Malmquist and Artur Scherf

Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer pp. 436-439

Jae Myoung Suh, Johan W. Jonker, Maryam Ahmadian, Regina Goetz, Denise Lackey, Olivia Osborn, Zhifeng Huang, Weilin Liu, Eiji Yoshihara, Theo H. van Dijk, Rick Havinga, Weiwei Fan, Yun-Qiang Yin, Ruth T. Yu, Christopher Liddle, Annette R. Atkins, Jerrold M. Olefsky, Moosa Mohammadi, Michael Downes and Ronald M. Evans

Coordinated regulation of protein synthesis and degradation by mTORC1 pp. 440-443

Yinan Zhang, Justin Nicholatos, John R. Dreier, Stéphane J. H. Ricoult, Scott B. Widenmaier, Gökhan S. Hotamisligil, David J. Kwiatkowski and Brendan D. Manning

Retraction Note: Genomic organization of human transcription initiation complexes pp. 444-444

Bryan J. Venters and B. Franklin Pugh

Correction: Corrigendum: Systems survey of endocytosis by multiparametric image analysis pp. 444-444

Claudio Collinet, Martin Stöter, Charles R. Bradshaw, Nikolay Samusik, Jochen C. Rink, Denise Kenski, Bianca Habermann, Frank Buchholz, Robert Henschel, Matthias S. Mueller, Wolfgang E. Nagel, Eugenio Fava, Yannis Kalaidzidis and Marino Zerial

When disease strikes from nowhere pp. 445-448

Vivien Marx

Early-career funding: Big introductions pp. 449-451

Quirin Schiermeier

Extraction pp. 454-454

Rebecca Roland

2014, volume 513, articles 7517

Lung cancer pp. S1-S1

Herb Brody

Epidemiology: The dominant malignancy pp. S2-S3

Eric Bender

Diagnosis: Early warning system pp. S4-S6

Katherine Bourzac

Perspective: The screening imperative pp. S7-S7

John K. Field

Personalized medicine: Special treatment pp. S8-S9

Michael Eisenstein

Immunotherapy: Chemical tricks pp. S10-S11

Bianca Nogrady

Aetiology: Crucial clues pp. S12-S13

Sarah Deweerdt

Environment: Breathing trouble pp. S14-S15

Traci Watson

Public health: A burning issue pp. S16-S17

Nidhi Subbaraman

Make diagnostic centres a priority for Ebola crisis pp. 145-145

J. Daniel Kelly

Scientists split over Scottish independence vote pp. 151-152

Elizabeth Gibney

Plate tectonics found on Europa pp. 153-154

Alexandra Witze

Chinese data hint at trigger for fatal quake pp. 154-155

Jane Qiu

NASA to send 3D printer into space pp. 156-156

Alexandra Witze

Wildlife energy: Survival of the fittest pp. 157-159

Andrew Curry

Curing blindness: Vision quest pp. 160-162

Corie Lok

Climate policy: Rethink IPCC reports pp. 163-165

Thomas F. Stocker and Gian-Kasper Plattner

Economics: Manufacture renewables to build energy security pp. 166-168

John A. Mathews and Hao Tan

Science fiction: Verne and beyond pp. 169-170

Danièle Chatelain and George Slusser

Q&A: The sci-fi optimist pp. 170-171

Zeeya Merali

Books in brief pp. 171-171

Barbara Kiser

Frame retractions so they hold firm pp. 172-172

Joachim Kirsch and Hans Schöler

Pregnancy: Study the mother's DNA as well pp. 172-172

Hannah Landecker

Pregnancy: No safe level of alcohol pp. 172-172

Elizabeth R. Sowell, Michael E. Charness and Edward P. Riley

Count the social cost of oil sands too pp. 172-172

Stephanie Montesanti

Consider human will in psychology studies pp. 172-172

Warren Mansell and Timothy A. Carey

Something to swing about pp. 174-175

Michael J. O'Neill and Rachel J. O'Neill

Bacteria get vaccinated pp. 175-176

Rodolphe Barrangou and Todd R. Klaenhammer

No equatorial divide for a cleansing radical pp. 176-178

Arlene M. Fiore

The promise and perils of roads pp. 178-179

Stephen G. Perz

What goes down must come up pp. 179-180

Raffaele Ferrari

Sound processing takes motor control pp. 180-181

Uri Livneh and Anthony Zador

Quasar complexity simplified pp. 181-182

Michael S. Brotherton

Assembly-line synthesis of organic molecules with tailored shapes pp. 183-188

Matthew Burns, Stéphanie Essafi, Jessica R. Bame, Stephanie P. Bull, Matthew P. Webster, Sébastien Balieu, James W. Dale, Craig P. Butts, Jeremy N. Harvey and Varinder K. Aggarwal

A synaptic and circuit basis for corollary discharge in the auditory cortex pp. 189-194

David M. Schneider, Anders Nelson and Richard Mooney

Gibbon genome and the fast karyotype evolution of small apes pp. 195-201

Lucia Carbone, R. Alan Harris, Sante Gnerre, Krishna R. Veeramah, Belen Lorente-Galdos, John Huddleston, Thomas J. Meyer, Javier Herrero, Christian Roos, Bronwen Aken, Fabio Anaclerio, Nicoletta Archidiacono, Carl Baker, Daniel Barrell, Mark A. Batzer, Kathryn Beal, Antoine Blancher, Craig L. Bohrson, Markus Brameier, Michael S. Campbell, Oronzo Capozzi, Claudio Casola, Giorgia Chiatante, Andrew Cree, Annette Damert, Pieter J. de Jong, Laura Dumas, Marcos Fernandez-Callejo, Paul Flicek, Nina V. Fuchs, Ivo Gut, Marta Gut, Matthew W. Hahn, Jessica Hernandez-Rodriguez, LaDeana W. Hillier, Robert Hubley, Bianca Ianc, Zsuzsanna Izsvák, Nina G. Jablonski, Laurel M. Johnstone, Anis Karimpour-Fard, Miriam K. Konkel, Dennis Kostka, Nathan H. Lazar, Sandra L. Lee, Lora R. Lewis, Yue Liu, Devin P. Locke, Swapan Mallick, Fernando L. Mendez, Matthieu Muffato, Lynne V. Nazareth, Kimberly A. Nevonen, Majesta O’Bleness, Cornelia Ochis, Duncan T. Odom, Katherine S. Pollard, Javier Quilez, David Reich, Mariano Rocchi, Gerald G. Schumann, Stephen Searle, James M. Sikela, Gabriella Skollar, Arian Smit, Kemal Sonmez, Boudewijn ten Hallers, Elizabeth Terhune, Gregg W. C. Thomas, Brygg Ullmer, Mario Ventura, Jerilyn A. Walker, Jeffrey D. Wall, Lutz Walter, Michelle C. Ward, Sarah J. Wheelan, Christopher W. Whelan, Simon White, Larry J. Wilhelm, August E. Woerner, Mark Yandell, Baoli Zhu, Michael F. Hammer, Tomas Marques-Bonet, Evan E. Eichler, Lucinda Fulton, Catrina Fronick, Donna M. Muzny, Wesley C. Warren, Kim C. Worley, Jeffrey Rogers, Richard K. Wilson and Richard A. Gibbs

The diversity of quasars unified by accretion and orientation pp. 210-213

Yue Shen and Luis C. Ho

Probing excitonic dark states in single-layer tungsten disulphide pp. 214-218

Ziliang Ye, Ting Cao, Kevin O’Brien, Hanyu Zhu, Xiaobo Yin, Yuan Wang, Steven G. Louie and Xiang Zhang

Observational evidence for interhemispheric hydroxyl-radical parity pp. 219-223

P. K. Patra, M. C. Krol, S. A. Montzka, T. Arnold, E. L. Atlas, B. R. Lintner, B. B. Stephens, B. Xiang, J. W. Elkins, P. J. Fraser, A. Ghosh, E. J. Hintsa, D. F. Hurst, K. Ishijima, P. B. Krummel, B. R. Miller, K. Miyazaki, F. L. Moore, J. Mühle, S. O’Doherty, R. G. Prinn, L. P. Steele, M. Takigawa, H. J. Wang, R. F. Weiss, S. C. Wofsy and D. Young

A major advance of tropical Andean glaciers during the Antarctic cold reversal pp. 224-228

V. Jomelli, V. Favier, M. Vuille, R. Braucher, L. Martin, P.-H. Blard, C. Colose, D. Brunstein, F. He, M. Khodri, D. L. Bourlès, L. Leanni, V. Rinterknecht, D. Grancher, B. Francou, J. L. Ceballos, H. Fonseca, Z. Liu and B. L. Otto-Bliesner

A global strategy for road building pp. 229-232

William F. Laurance, Gopalasamy Reuben Clements, Sean Sloan, Christine S. O’Connell, Nathan D. Mueller, Miriam Goosem, Oscar Venter, David P. Edwards, Ben Phalan, Andrew Balmford, Rodney Van Der Ree and Irene Burgues Arrea

The evolution of the placenta drives a shift in sexual selection in livebearing fish pp. 233-236

B. J. A. Pollux, R. W. Meredith, M. S. Springer, T. Garland and D. N. Reznick

Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome pp. 237-241

Hao Xu, Jieling Yang, Wenqing Gao, Lin Li, Peng Li, Li Zhang, Yi-Nan Gong, Xiaolan Peng, Jianzhong Jeff Xi, She Chen, Fengchao Wang and Feng Shao

Viral tagging reveals discrete populations in Synechococcus viral genome sequence space pp. 242-245

Li Deng, J. Cesar Ignacio-Espinoza, Ann C. Gregory, Bonnie T. Poulos, Joshua S. Weitz, Philip Hugenholtz and Matthew B. Sullivan

Carbonic anhydrases, EPF2 and a novel protease mediate CO2 control of stomatal development pp. 246-250

Cawas B. Engineer, Majid Ghassemian, Jeffrey C. Anderson, Scott C. Peck, Honghong Hu and Julian I. Schroeder

Fructose-1,6-bisphosphatase opposes renal carcinoma progression pp. 251-255

Bo Li, Bo Qiu, David S. M. Lee, Zandra E. Walton, Joshua D. Ochocki, Lijoy K. Mathew, Anthony Mancuso, Terence P. F. Gade, Brian Keith, Itzhak Nissim and M. Celeste Simon

Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins pp. 256-260

Hani Goodarzi, Steven Zhang, Colin G. Buss, Lisa Fish, Saeed Tavazoie and Sohail F. Tavazoie

Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser pp. 261-265

Christopher Kupitz, Shibom Basu, Ingo Grotjohann, Raimund Fromme, Nadia A. Zatsepin, Kimberly N. Rendek, Mark S. Hunter, Robert L. Shoeman, Thomas A. White, Dingjie Wang, Daniel James, Jay-How Yang, Danielle E. Cobb, Brenda Reeder, Raymond G. Sierra, Haiguang Liu, Anton Barty, Andrew L. Aquila, Daniel Deponte, Richard A. Kirian, Sadia Bari, Jesse J. Bergkamp, Kenneth R. Beyerlein, Michael J. Bogan, Carl Caleman, Tzu-Chiao Chao, Chelsie E. Conrad, Katherine M. Davis, Holger Fleckenstein, Lorenzo Galli, Stefan P. Hau-Riege, Stephan Kassemeyer, Hartawan Laksmono, Mengning Liang, Lukas Lomb, Stefano Marchesini, Andrew V. Martin, Marc Messerschmidt, Despina Milathianaki, Karol Nass, Alexandra Ros, Shatabdi Roy-Chowdhury, Kevin Schmidt, Marvin Seibert, Jan Steinbrener, Francesco Stellato, Lifen Yan, Chunhong Yoon, Thomas A. Moore, Ana L. Moore, Yulia Pushkar, Garth J. Williams, Sébastien Boutet, R. Bruce Doak, Uwe Weierstall, Matthias Frank, Henry N. Chapman, John C. H. Spence and Petra Fromme

Correction: Corrigendum: Mitofusin 2 tethers endoplasmic reticulum to mitochondria pp. 266-266

Olga Martins de Brito and Luca Scorrano

Correction: Corrigendum: Direct recording and molecular identification of the calcium channel of primary cilia pp. 266-266

Paul G. DeCaen, Markus Delling, Thuy N. Vien and David E. Clapham

Job satisfaction: Divided opinions pp. 267-269

Paul Smaglik, Karen Kaplan, Shirana Kelly and Dan Penny

The tiger waiting on the shore pp. 272-272

Paul Currion

2014, volume 513, articles 7516

Judge research impact on a local scale pp. 7-7

Casparus J Crous

Fresh arguments over old data pp. 9-9

Chris Woolston

Ebola drug trials set to begin amid crisis pp. 13-14

Declan Butler

Stalled El Niño poised to resurge pp. 15-15

Mark Zastrow

Switzerland braces for Alpine lake tsunami pp. 16-17

Laura Spinney

California quake puts warning system in the spotlight pp. 18-18

Alexandra Witze

Life outside the lab: The ones who got away pp. 20-22

Ewen Callaway

E-cigarettes: The lingering questions pp. 24-26

Daniel Cressey

Neuroscience: Where is the brain in the Human Brain Project? pp. 27-29

Yves Frégnac and Gilles Laurent

Satellites: Make Earth observations open access pp. 30-31

Michael A. Wulder and Nicholas C. Coops

Developmental biology: Splitting the sexes pp. 32-32

Virginia Valian

Energy: Social fixes are on the up pp. 33-33

David E. Rodgers and Dustin S. Schinn

Energy: We need all hands on deck pp. 33-33

Paul C. Stern

Energy: Humanities frame the aims pp. 33-33

Noel Castree

Better monitoring of fish in dam projects pp. 33-33

Peter Brewitt and Karen D. Holl

Seals collect more Southern Ocean data pp. 33-33

Clive R. McMahon and Robert Harcourt

Yoshiki Sasai (1962–2014) pp. 34-34

Arturo Alvarez-Buylla

How plumes help to break plates pp. 36-37

Susanne Buiter

Dynasty of the plastic fish pp. 37-38

John Hutchinson

A guardian angel of cell integrity pp. 38-39

Francis Ka-Ming Chan

Edit the genome to understand it pp. 40-41

Fyodor D. Urnov

Meet the Laniakea supercluster pp. 41-42

Elmo Tempel

How fluorescent RNA gets its glow pp. 42-43

William G. Scott

Migrations and dynamics of the intertropical convergence zone pp. 45-53

Tapio Schneider, Tobias Bischoff and Gerald H. Haug

Developmental plasticity and the origin of tetrapods pp. 54-58

Emily M. Standen, Trina Y. Du and Hans C. E. Larsson

Alterations of the human gut microbiome in liver cirrhosis pp. 59-64

Nan Qin, Fengling Yang, Ang Li, Edi Prifti, Yanfei Chen, Li Shao, Jing Guo, Emmanuelle Le Chatelier, Jian Yao, Lingjiao Wu, Jiawei Zhou, Shujun Ni, Lin Liu, Nicolas Pons, Jean Michel Batto, Sean P. Kennedy, Pierre Leonard, Chunhui Yuan, Wenchao Ding, Yuanting Chen, Xinjun Hu, Beiwen Zheng, Guirong Qian, Wei Xu, S. Dusko Ehrlich, Shusen Zheng and Lanjuan Li

RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer pp. 65-70

Andrew L. Wolfe, Kamini Singh, Yi Zhong, Philipp Drewe, Vinagolu K. Rajasekhar, Viraj R. Sanghvi, Konstantinos J. Mavrakis, Man Jiang, Justine E. Roderick, Joni Van der Meulen, Jonathan H. Schatz, Christina M. Rodrigo, Chunying Zhao, Pieter Rondou, Elisa de Stanchina, Julie Teruya-Feldstein, Michelle A. Kelliher, Frank Speleman, John A. Porco, Jerry Pelletier, Gunnar Rätsch and Hans-Guido Wendel

The Laniakea supercluster of galaxies pp. 71-73

R. Brent Tully, Hélène Courtois, Yehuda Hoffman and Daniel Pomarède

A 400-solar-mass black hole in the galaxy M82 pp. 74-76

Dheeraj R. Pasham, Tod E. Strohmayer and Richard F. Mushotzky

Hierarchical organization of chiral rafts in colloidal membranes pp. 77-80

Prerna Sharma, Andrew Ward, T. Gibaud, Michael F. Hagan and Zvonimir Dogic

Temperature sensitivity of soil respiration rates enhanced by microbial community response pp. 81-84

Kristiina Karhu, Marc D. Auffret, Jennifer A. J. Dungait, David W. Hopkins, James I. Prosser, Brajesh K. Singh, Jens-Arne Subke, Philip A. Wookey, Göran I. Ågren, Maria-Teresa Sebastià, Fabrice Gouriveau, Göran Bergkvist, Patrick Meir, Andrew T. Nottingham, Norma Salinas and Iain P. Hartley

Asymmetric three-dimensional topography over mantle plumes pp. 85-89

Evgueni Burov and Taras Gerya

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis pp. 90-94

Marius Dannappel, Katerina Vlantis, Snehlata Kumari, Apostolos Polykratis, Chun Kim, Laurens Wachsmuth, Christina Eftychi, Juan Lin, Teresa Corona, Nicole Hermance, Matija Zelic, Petra Kirsch, Marijana Basic, Andre Bleich, Michelle Kelliher and Manolis Pasparakis

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis pp. 95-99

Nozomi Takahashi, Lars Vereecke, Mathieu J. M. Bertrand, Linde Duprez, Scott B. Berger, Tatyana Divert, Amanda Gonçalves, Mozes Sze, Barbara Gilbert, Stephanie Kourula, Vera Goossens, Sylvie Lefebvre, Claudia Günther, Christoph Becker, John Bertin, Peter J. Gough, Wim Declercq, Geert van Loo and Peter Vandenabeele

Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia pp. 100-104

Serkan Kir, James P. White, Sandra Kleiner, Lawrence Kazak, Paul Cohen, Vickie E. Baracos and Bruce M. Spiegelman

eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies pp. 105-109

Lise Boussemart, Hélène Malka-Mahieu, Isabelle Girault, Delphine Allard, Oskar Hemmingsson, Gorana Tomasic, Marina Thomas, Christine Basmadjian, Nigel Ribeiro, Frédéric Thuaud, Christina Mateus, Emilie Routier, Nyam Kamsu-Kom, Sandrine Agoussi, Alexander M. Eggermont, Laurent Désaubry, Caroline Robert and Stéphan Vagner

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer pp. 110-114

Supriya K. Saha, Christine A. Parachoniak, Krishna S. Ghanta, Julien Fitamant, Kenneth N. Ross, Mortada S. Najem, Sushma Gurumurthy, Esra A. Akbay, Daniela Sia, Helena Cornella, Oriana Miltiadous, Chad Walesky, Vikram Deshpande, Andrew X. Zhu, Aram F. Hezel, Katharine E. Yen, Kimberly S. Straley, Jeremy Travins, Janeta Popovici-Muller, Camelia Gliser, Cristina R. Ferrone, Udayan Apte, Josep M. Llovet, Kwok-Kin Wong, Sridhar Ramaswamy and Nabeel Bardeesy

Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells pp. 115-119

Zohar Shipony, Zohar Mukamel, Netta Mendelson Cohen, Gilad Landan, Elad Chomsky, Shlomit Reich Zeliger, Yael Chagit Fried, Elena Ainbinder, Nir Friedman and Amos Tanay

Saturation editing of genomic regions by multiplex homology-directed repair pp. 120-123

Gregory M. Findlay, Evan A. Boyle, Ronald J. Hause, Jason C. Klein and Jay Shendure

High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875 pp. 124-127

Ankita Srivastava, Jason Yano, Yoshihiko Hirozane, Georgia Kefala, Franz Gruswitz, Gyorgy Snell, Weston Lane, Anthony Ivetac, Kathleen Aertgeerts, Jasmine Nguyen, Andy Jennings and Kengo Okada

Correction: Corrigendum: Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET pp. 128-128

Toshiyuki Matsui, Danny Leung, Hiroki Miyashita, Irina A. Maksakova, Hitoshi Miyachi, Hiroshi Kimura, Makoto Tachibana, Matthew C. Lorincz and Yoichi Shinkai

How to tame the flood of literature pp. 129-130

Elizabeth Gibney

Interviews: The all-important job talk pp. 131-133

Amanda Mascarelli

Turning point: Shingo Kajimura pp. 133-133

Scott Kraft

Investments pp. 136-136

Simon Kewin