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2021, volume 593, articles 7860

Fresh twists in China’s bid for research dominance pp. S1-S1

Catherine Armitage

Silk Road becomes the one less travelled as China lures science talent home pp. S2-S3

Catherine Armitage and Chris Woolston

Author Correction: Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH pp. E14-E14

Michael Dudek, Dominik Pfister, Sainitin Donakonda, Pamela Filpe, Annika Schneider, Melanie Laschinger, Daniel Hartmann, Norbert Hüser, Philippa Meiser, Felix Bayerl, Donato Inverso, Jennifer Wigger, Marcial Sebode, Rupert Öllinger, Roland Rad, Silke Hegenbarth, Martina Anton, Adrien Guillot, Andrew Bowman, Danijela Heide, Florian Müller, Pierluigi Ramadori, Valentina Leone, Cristina Garcia-Caceres, Tim Gruber, Gabriel Seifert, Agnieszka M. Kabat, Jan-Philipp Mallm, Simon Reider, Maria Effenberger, Susanne Roth, Adrian T. Billeter, Beat Müller-Stich, Edward J. Pearce, Friedrich Koch-Nolte, Rafael Käser, Herbert Tilg, Robert Thimme, Tobias Boettler, Frank Tacke, Jean-Francois Dufour, Dirk Haller, Peter J. Murray, Ron Heeren, Dietmar Zehn, Jan P. Böttcher, Mathias Heikenwälder and Percy A. Knolle

Five science stars making their mark in China pp. S14-S17

Gemma Conroy, Flynn Murphy and Sian Powell

Publisher Correction: Whole-genome doubling confers unique genetic vulnerabilities on tumour cells pp. E15-E15

Ryan J. Quinton, Amanda DiDomizio, Marc A. Vittoria, Kristýna Kotýnková, Carlos J. Ticas, Sheena Patel, Yusuke Koga, Jasmine Vakhshoorzadeh, Nicole Hermance, Taruho S. Kuroda, Neha Parulekar, Alison M. Taylor, Amity L. Manning, Joshua D. Campbell and Neil J. Ganem

China’s leading researchers set their sights on new frontiers pp. S24-S27

Hepeng Jia, Sian Powell and Kevin Schoenmakers

Chinese joint-venture universities try for the best of both worlds pp. S28-S28

Cong Cao

Stem-cell guidelines: why it was time for an update pp. 479-479

Robin Lovell-Badge

India’s neighbours race to sequence genomes as COVID surges pp. 485-486

Smriti Mallapaty

First nuclear detonation created ‘impossible’ quasicrystals pp. 487-487

Davide Castelvecchi

‘It’s a minefield’: COVID vaccine safety poses unique communication challenge pp. 488-489

Ariana Remmel

Open-access publisher PLOS pushes to extend clout beyond biomedicine pp. 489-490

Holly Else

Prestigious European grants might be biased, study suggests pp. 490-491

Diana Kwon

Mix-and-match COVID vaccines trigger potent immune response pp. 491-491

Ewen Callaway

The mini lungs and other organoids helping to beat COVID pp. 492-494

Smriti Mallapaty

What the science says about lifting mask mandates pp. 495-498

Lynne Peeples

AI — the people and places that make, use and manage it pp. 499-500

Virginia Dignum

A physicist goes in search of our origins pp. 500-501

Andrea Taroni

Count the cost of disability caused by COVID-19 pp. 502-505

Andrew Briggs and Anna Vassall

Tissues, not blood, are where immune cells function pp. 506-509

Donna L. Farber

Vaccination: Brazil fails Indigenous people again with two-tier scheme pp. 510-510

Ana Carla dos Santos Costa, Shoaib Ahmad and Mohammad Yasir Essar

Deploy international satellite monitoring to safeguard forests pp. 510-510

Ricardo M. O. Galvão

EU forest strategy: adapt, innovate, employ pp. 510-510

Marc Palahí

Trade resolution further threatens Brazil’s amphibians pp. 510-510

Joice Ruggeri and Lucas Rodriguez Forti

Fibroblast cells reveal their ancestry pp. 511-512

Christopher D. Buckley

Nanocrystals form a superfluorescent lattice mimicking the atomic structure of perovskite materials pp. 513-514

Gerd Bacher

A mitochondrial gatekeeper that helps cells escape death by ferroptosis pp. 514-515

Javier Garcia-Bermudez and Kıvanç Birsoy

Trip frequency is key ingredient in new law of human travel pp. 515-516

Laura Alessandretti and Sune Lehmann

Evidence of hydrogen−helium immiscibility at Jupiter-interior conditions pp. 517-521

S. Brygoo, P. Loubeyre, M. Millot, J. R. Rygg, P. M. Celliers, J. H. Eggert, R. Jeanloz and G. W. Collins

The universal visitation law of human mobility pp. 522-527

Markus Schläpfer, Lei Dong, Kevin O’Keeffe, Paolo Santi, Michael Szell, Hadrien Salat, Samuel Anklesaria, Mohammad Vazifeh, Carlo Ratti and Geoffrey B. West

Long-range nontopological edge currents in charge-neutral graphene pp. 528-534

A. Aharon-Steinberg, A. Marguerite, D. J. Perello, K. Bagani, T. Holder, Y. Myasoedov, L. S. Levitov, A. K. Geim and E. Zeldov

Perovskite-type superlattices from lead halide perovskite nanocubes pp. 535-542

Ihor Cherniukh, Gabriele Rainò, Thilo Stöferle, Max Burian, Alex Travesset, Denys Naumenko, Heinz Amenitsch, Rolf Erni, Rainer F. Mahrt, Maryna I. Bodnarchuk and Maksym V. Kovalenko

RETRACTED ARTICLE: A 10 per cent increase in global land evapotranspiration from 2003 to 2019 pp. 543-547

Madeleine Pascolini-Campbell, John T. Reager, Hrishikesh A. Chandanpurkar and Matthew Rodell

Overriding water table control on managed peatland greenhouse gas emissions pp. 548-552

C. D. Evans, M. Peacock, A. J. Baird, R. R. E. Artz, A. Burden, N. Callaghan, P. J. Chapman, H. M. Cooper, M. Coyle, E. Craig, A. Cumming, S. Dixon, V. Gauci, R. P. Grayson, C. Helfter, C. M. Heppell, J. Holden, D. L. Jones, J. Kaduk, P. Levy, R. Matthews, N. P. McNamara, T. Misselbrook, S. Oakley, S. E. Page, M. Rayment, L. M. Ridley, K. M. Stanley, J. L. Williamson, F. Worrall and R. Morrison

Expanded diversity of Asgard archaea and their relationships with eukaryotes pp. 553-557

Yang Liu, Kira S. Makarova, Wen-Cong Huang, Yuri I. Wolf, Anastasia N. Nikolskaya, Xinxu Zhang, Mingwei Cai, Cui-Jing Zhang, Wei Xu, Zhuhua Luo, Lei Cheng, Eugene V. Koonin and Meng Li

Fast odour dynamics are encoded in the olfactory system and guide behaviour pp. 558-563

Tobias Ackels, Andrew Erskine, Debanjan Dasgupta, Alina Cristina Marin, Tom P. A. Warner, Sina Tootoonian, Izumi Fukunaga, Julia J. Harris and Andreas T. Schaefer

The spatial landscape of lung pathology during COVID-19 progression pp. 564-569

André F. Rendeiro, Hiranmayi Ravichandran, Yaron Bram, Vasuretha Chandar, Junbum Kim, Cem Meydan, Jiwoon Park, Jonathan Foox, Tyler Hether, Sarah Warren, Youngmi Kim, Jason Reeves, Steven Salvatore, Christopher E. Mason, Eric C. Swanson, Alain C. Borczuk, Olivier Elemento and Robert E. Schwartz

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit pp. 570-574

Boram Kim, Makoto I. Kanai, Yangkyun Oh, Minsoo Kyung, Eun-Kyoung Kim, In-Hwan Jang, Ji-Hoon Lee, Sang-Gyu Kim, Greg S. B. Suh and Won-Jae Lee

Cross-tissue organization of the fibroblast lineage pp. 575-579

Matthew B. Buechler, Rachana N. Pradhan, Akshay T. Krishnamurty, Christian Cox, Aslihan Karabacak Calviello, Amber W. Wang, Yeqing Angela Yang, Lucinda Tam, Roger Caothien, Merone Roose-Girma, Zora Modrusan, Joseph R. Arron, Richard Bourgon, Sören Müller and Shannon. J. Turley

Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine pp. 580-585

Yizhi Sun, Janane F. Rahbani, Mark P. Jedrychowski, Christopher L. Riley, Sara Vidoni, Dina Bogoslavski, Bo Hu, Phillip A. Dumesic, Xing Zeng, Alex B. Wang, Nelson H. Knudsen, Caroline R. Kim, Anthony Marasciullo, José L. Millán, Edward T. Chouchani, Lawrence Kazak and Bruce M. Spiegelman

DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer pp. 586-590

Chao Mao, Xiaoguang Liu, Yilei Zhang, Guang Lei, Yuelong Yan, Hyemin Lee, Pranavi Koppula, Shiqi Wu, Li Zhuang, Bingliang Fang, Masha V. Poyurovsky, Kellen Olszewski and Boyi Gan

Replication stress promotes cell elimination by extrusion pp. 591-596

Vivek K. Dwivedi, Carlos Pardo-Pastor, Rita Droste, Ji Na Kong, Nolan Tucker, Daniel P. Denning, Jody Rosenblatt and H. Robert Horvitz

Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia pp. 597-601

Eliza Yankova, Wesley Blackaby, Mark Albertella, Justyna Rak, Etienne Braekeleer, Georgia Tsagkogeorga, Ewa S. Pilka, Demetrios Aspris, Dan Leggate, Alan G. Hendrick, Natalie A. Webster, Byron Andrews, Richard Fosbeary, Patrick Guest, Nerea Irigoyen, Maria Eleftheriou, Malgorzata Gozdecka, Joao M. L. Dias, Andrew J. Bannister, Binje Vick, Irmela Jeremias, George S. Vassiliou, Oliver Rausch, Konstantinos Tzelepis and Tony Kouzarides

Global miRNA dosage control of embryonic germ layer specification pp. 602-606

Yingzi Cui, Xuehui Lyu, Li Ding, Lan Ke, Dechang Yang, Mehdi Pirouz, Ye Qi, Jennie Ong, Ge Gao, Peng Du and Richard I. Gregory

Gasdermin D pore structure reveals preferential release of mature interleukin-1 pp. 607-611

Shiyu Xia, Zhibin Zhang, Venkat Giri Magupalli, Juan Lorenzo Pablo, Ying Dong, Setu M. Vora, Longfei Wang, Tian-Min Fu, Matthew P. Jacobson, Anna Greka, Judy Lieberman, Jianbin Ruan and Hao Wu

Retraction Note: Endoperoxide formation by an α-ketoglutarate-dependent mononuclear non-haem iron enzyme pp. 612-612

Wupeng Yan, Heng Song, Fuhang Song, Yisong Guo, Cheng-Hsuan Wu, Ampon Sae Her, Yi Pu, Shu Wang, Nathchar Naowarojna, Andrew Weitz, Michael P. Hendrich, Catherine E. Costello, Lixin Zhang, Pinghua Liu and Yan Jessie Zhang

How COVID-19 has stomped on scientists’ travel plans pp. 613-615

Chris Woolston

How waste water is helping South Africa fight COVID-19 pp. 616-617

Heather Richardson

In software, the name of the game is innovation pp. 620-620

Kendall Powell

2021, volume 593, articles 7859

Media bias delegitimizes Black-rights protesters pp. 315-315

Danielle Kilgo

Coronavirus variants are spreading in India — what scientists know so far pp. 321-322

Gayathri Vaidyanathan

China has landed its first rover on Mars — here’s what happens next pp. 323-324

Smriti Mallapaty

NASA reboots its role in fighting climate change pp. 324-325

Alexandra Witze

Pfizer COVID vaccine protects against worrying coronavirus variants pp. 325-326

Ewen Callaway

How many COVID deaths are acceptable in a post-pandemic world? pp. 326-327

Smriti Mallapaty

The mysterious microbes that gave rise to complex life pp. 328-330

Amber Dance

How COVID is changing the study of human behaviour pp. 331-333

Christie Aschwanden

The singing neutrino Nobel laureate who nearly bombed Nevada pp. 334-335

Alison Abbott

C. Austen Angell (1933–2021) pp. 336-336

Pablo G. Debenedetti, Peter H. Poole, Srikanth Sastry and Francesco Sciortino

Craft an African American Graves Protection and Repatriation Act pp. 337-340

Justin Dunnavant, Delande Justinvil and Chip Colwell

Statistics: unify ecosystems valuation pp. 341-341

Nils Brown, Aldo Femia, Dennis Fixler, Ole Gravgård Pedersen, Sven C. Kaumanns, Gian Paolo Oneto, Simon Schürz, Francesco N. Tubiello and Scott Wentland

Virus variants: GISAID policies incentivize surveillance in global south pp. 341-341

Jeremy P. Kamil

UNESCO embraces open science to shape society’s future pp. 341-341

Audrey Azoulay

Contrails: tweaking flight altitude could be a climate win pp. 341-341

Ken Caldeira and Ian McKay

Previously unknown type of protein crosslink discovered pp. 343-344

Deborah Fass and Sergey N. Semenov

Ultracold chemical reactions reveal the quantum mechanism of product formation pp. 344-345

Nandini Mukherjee

Revolutionary view of two ways to split a mitochondrion pp. 346-347

Rajarshi Chakrabarti and Henry N. Higgs

Conversations, and how we end them pp. 347-349

Elizabeth Stokoe

Iron and nickel vapours are present in most comets pp. 349-350

Dennis Bodewits and Steven J. Bromley

The data-driven future of high-energy-density physics pp. 351-361

Peter W. Hatfield, Jim A. Gaffney, Gemma J. Anderson, Suzanne Ali, Luca Antonelli, Suzan Başeğmez du Pree, Jonathan Citrin, Marta Fajardo, Patrick Knapp, Brendan Kettle, Bogdan Kustowski, Michael J. MacDonald, Derek Mariscal, Madison E. Martin, Taisuke Nagayama, Charlotte A. J. Palmer, J. Luc Peterson, Steven Rose, J J Ruby, Carl Shneider, Matt J. V. Streeter, Will Trickey and Ben Williams

Unconventional viral gene expression mechanisms as therapeutic targets pp. 362-371

Jessica Sook Yuin Ho, Zeyu Zhu and Ivan Marazzi

Iron and nickel atoms in cometary atmospheres even far from the Sun pp. 372-374

J. Manfroid, D. Hutsemékers and E. Jehin

Gaseous atomic nickel in the coma of interstellar comet 2I/Borisov pp. 375-378

Piotr Guzik and Michał Drahus

Precision test of statistical dynamics with state-to-state ultracold chemistry pp. 379-384

Yu Liu, Ming-Guang Hu, Matthew A. Nichols, Dongzheng Yang, Daiqian Xie, Hua Guo and Kang-Kuen Ni

Tunable non-integer high-harmonic generation in a topological insulator pp. 385-390

C. P. Schmid, L. Weigl, P. Grössing, V. Junk, C. Gorini, S. Schlauderer, S. Ito, M. Meierhofer, N. Hofmann, D. Afanasiev, J. Crewse, K. A. Kokh, O. E. Tereshchenko, J. Güdde, F. Evers, J. Wilhelm, K. Richter, U. Höfer and R. Huber

Discovery, characterization and engineering of ligases for amide synthesis pp. 391-398

Michael Winn, Michael Rowlinson, Fanghua Wang, Luis Bering, Daniel Francis, Colin Levy and Jason Micklefield

Overwintering fires in boreal forests pp. 399-404

Rebecca C. Scholten, Randi Jandt, Eric A. Miller, Brendan M. Rogers and Sander Veraverbeke

Somatic mutation landscapes at single-molecule resolution pp. 405-410

Federico Abascal, Luke M. R. Harvey, Emily Mitchell, Andrew R. J. Lawson, Stefanie V. Lensing, Peter Ellis, Andrew J. C. Russell, Raul E. Alcantara, Adrian Baez-Ortega, Yichen Wang, Eugene Jing Kwa, Henry Lee-Six, Alex Cagan, Tim H. H. Coorens, Michael Spencer Chapman, Sigurgeir Olafsson, Steven Leonard, David Jones, Heather E. Machado, Megan Davies, Nina F. Øbro, Krishnaa T. Mahubani, Kieren Allinson, Moritz Gerstung, Kourosh Saeb-Parsy, David G. Kent, Elisa Laurenti, Michael R. Stratton, Raheleh Rahbari, Peter J. Campbell, Robert J. Osborne and Iñigo Martincorena

Mouse prefrontal cortex represents learned rules for categorization pp. 411-417

Sandra Reinert, Mark Hübener, Tobias Bonhoeffer and Pieter M. Goltstein

Clofazimine broadly inhibits coronaviruses including SARS-CoV-2 pp. 418-423

Shuofeng Yuan, Xin Yin, Xiangzhi Meng, Jasper Fuk-Woo Chan, Zi-Wei Ye, Laura Riva, Lars Pache, Chris Chun-Yiu Chan, Pok-Man Lai, Chris Chung-Sing Chan, Vincent Kwok-Man Poon, Andrew Chak-Yiu Lee, Naoko Matsunaga, Yuan Pu, Chun-Kit Yuen, Jianli Cao, Ronghui Liang, Kaiming Tang, Li Sheng, Yushen Du, Wan Xu, Chit-Ying Lau, Ko-Yung Sit, Wing-Kuk Au, Runming Wang, Yu-Yuan Zhang, Yan-Dong Tang, Thomas Mandel Clausen, Jessica Pihl, Juntaek Oh, Kong-Hung Sze, Anna Jinxia Zhang, Hin Chu, Kin-Hang Kok, Dong Wang, Xue-Hui Cai, Jeffrey D. Esko, Ivan Fan-Ngai Hung, Ronald Adolphus Li, Honglin Chen, Hongzhe Sun, Dong-Yan Jin, Ren Sun, Sumit K. Chanda and Kwok-Yung Yuen

Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice pp. 424-428

Raoul Gasparo, Mattia Pedotti, Luca Simonelli, Petr Nickl, Frauke Muecksch, Irene Cassaniti, Elena Percivalle, Julio C. C. Lorenzi, Federica Mazzola, Davide Magrì, Tereza Michalcikova, Jan Haviernik, Vaclav Honig, Blanka Mrazkova, Natalie Polakova, Andrea Fortova, Jolana Tureckova, Veronika Iatsiuk, Salvatore Girolamo, Martin Palus, Dagmar Zudova, Petr Bednar, Ivana Bukova, Filippo Bianchini, Dora Mehn, Radim Nencka, Petra Strakova, Oto Pavlis, Jan Rozman, Sabrina Gioria, Josè Camilla Sammartino, Federica Giardina, Stefano Gaiarsa, Qiang Pan-Hammarström, Christopher O. Barnes, Pamela J. Bjorkman, Luigi Calzolai, Antonio Piralla, Fausto Baldanti, Michel C. Nussenzweig, Paul D. Bieniasz, Theodora Hatziioannou, Jan Prochazka, Radislav Sedlacek, Davide F. Robbiani, Daniel Ruzek and Luca Varani

In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates pp. 429-434

Kiran Musunuru, Alexandra C. Chadwick, Taiji Mizoguchi, Sara P. Garcia, Jamie E. DeNizio, Caroline W. Reiss, Kui Wang, Sowmya Iyer, Chaitali Dutta, Victoria Clendaniel, Michael Amaonye, Aaron Beach, Kathleen Berth, Souvik Biswas, Maurine C. Braun, Huei-Mei Chen, Thomas V. Colace, John D. Ganey, Soumyashree A. Gangopadhyay, Ryan Garrity, Lisa N. Kasiewicz, Jennifer Lavoie, James A. Madsen, Yuri Matsumoto, Anne Marie Mazzola, Yusuf S. Nasrullah, Joseph Nneji, Huilan Ren, Athul Sanjeev, Madeleine Shay, Mary R. Stahley, Steven H. Y. Fan, Ying K. Tam, Nicole M. Gaudelli, Giuseppe Ciaramella, Leslie E. Stolz, Padma Malyala, Christopher J. Cheng, Kallanthottathil G. Rajeev, Ellen Rohde, Andrew M. Bellinger and Sekar Kathiresan

Distinct fission signatures predict mitochondrial degradation or biogenesis pp. 435-439

Tatjana Kleele, Timo Rey, Julius Winter, Sofia Zaganelli, Dora Mahecic, Hélène Perreten Lambert, Francesco Paolo Ruberto, Mohamed Nemir, Timothy Wai, Thierry Pedrazzini and Suliana Manley

Neuronal enhancers are hotspots for DNA single-strand break repair pp. 440-444

Wei Wu, Sarah E. Hill, William J. Nathan, Jacob Paiano, Elsa Callen, Dongpeng Wang, Kenta Shinoda, Niek Wietmarschen, Jennifer M. Colón-Mercado, Dali Zong, Raffaella Pace, Han-Yu Shih, Steve Coon, Maia Parsadanian, Raphael Pavani, Hana Hanzlikova, Solji Park, Seol Kyoung Jung, Peter J. McHugh, Andres Canela, Chongyi Chen, Rafael Casellas, Keith W. Caldecott, Michael E. Ward and André Nussenzweig

Structure and dynamics of a mycobacterial type VII secretion system pp. 445-448

Catalin M. Bunduc, Dirk Fahrenkamp, Jiri Wald, Roy Ummels, Wilbert Bitter, Edith N. G. Houben and Thomas C. Marlovits

Structure of human telomerase holoenzyme with bound telomeric DNA pp. 449-453

George E. Ghanim, Adam J. Fountain, Anne-Marie M. Roon, Ramya Rangan, Rhiju Das, Kathleen Collins and Thi Hoang Duong Nguyen

Structures of telomerase at several steps of telomere repeat synthesis pp. 454-459

Yao He, Yaqiang Wang, Baocheng Liu, Christina Helmling, Lukas Sušac, Ryan Cheng, Z. Hong Zhou and Juli Feigon

A lysine–cysteine redox switch with an NOS bridge regulates enzyme function pp. 460-464

Marie Wensien, Fabian Rabe Pappenheim, Lisa-Marie Funk, Patrick Kloskowski, Ute Curth, Ulf Diederichsen, Jon Uranga, Jin Ye, Pan Fang, Kuan-Ting Pan, Henning Urlaub, Ricardo A. Mata, Viktor Sautner and Kai Tittmann

University of Cape Town’s battle to tackle a racist legacy pp. 465-467

Linda Nordling

Designing nano-sized chemotherapy pp. 470-470

Virginia Gewin

2021, volume 593, articles 7858

Author Correction: A 20-year retrospective review of global aquaculture pp. E12-E12

Rosamond L. Naylor, Ronald W. Hardy, Alejandro H. Buschmann, Simon R. Bush, Ling Cao, Dane H. Klinger, David C. Little, Jane Lubchenco, Sandra E. Shumway and Max Troell

Author Correction: Towards real-time photorealistic 3D holography with deep neural networks pp. E13-E13

Liang Shi, Beichen Li, Changil Kim, Petr Kellnhofer and Wojciech Matusik

Stop the emerging AI cold war pp. 169-169

Denise Garcia

First genetically modified mosquitoes released in the United States pp. 175-176

Emily Waltz

Why some researchers oppose unrestricted sharing of coronavirus genome data pp. 176-177

Amy Maxmen

China’s COVID vaccines are going global — but questions remain pp. 178-179

Smriti Mallapaty

Failure of genetic therapies for Huntington’s devastates community pp. 180-180

Diana Kwon

Weird viral DNA spills secrets to biologists pp. 181-181

Ewen Callaway

How COVID broke the evidence pipeline pp. 182-185

Helen Pearson

From spoons to semiconductors — we are what we make pp. 186-187

Anna Novitzky

An incomparable intellectual who fell through the cracks of history pp. 188-189

Georgina Ferry

Elegant chemistry, a humane view of robots, and refugee economics: Books in brief pp. 189-189

Andrew Robinson

Thomas Cavalier-Smith (1942–2021) pp. 190-190

Thomas Richards

Nature-based solutions can help cool the planet — if we act now pp. 191-194

Cécile A. J. Girardin, Stuart Jenkins, Nathalie Seddon, Myles Allen, Simon L. Lewis, Charlotte E. Wheeler, Bronson W. Griscom and Yadvinder Malhi

Value of Mexican nature reserve is more than monetary pp. 195-195

Enrique J. Jardel-Peláez, Sergio Graf-Montero, Eduardo Santana-C. and Angélica Jiménez-Hernández

Afghanistan: vaccinate drug users against COVID-19 pp. 195-195

Attaullah Ahmadi, Blaise Ntacyabukura and Don Eliseo Lucero-Prisno

Stop using ‘master–slave’ terminology in biology pp. 195-195

Dan Graur

COVID-19: build on Belgium’s psychosocial findings pp. 195-195

Elke Van Hoof and Nele Van den Cruyce

Neural interface translates thoughts into type pp. 197-198

Pavithra Rajeswaran and Amy L. Orsborn

Cloud droplets aid the production of formic acid in the atmosphere pp. 198-199

Joost de Gouw and Delphine Farmer

A continuous model of early mammalian development pp. 200-201

Chengxiang Qiu and Jay Shendure

A molecular connection hints at how a genetic risk factor drives Crohn’s disease pp. 201-203

Scott Plevy

Nitrogen deletion offers fresh strategy for organic synthesis pp. 203-204

William P. Unsworth and Alyssa-Jennifer Avestro

CMOS-based cryogenic control of silicon quantum circuits pp. 205-210

Xiao Xue, Bishnu Patra, Jeroen P. G. Dijk, Nodar Samkharadze, Sushil Subramanian, Andrea Corna, Brian Paquelet Wuetz, Charles Jeon, Farhana Sheikh, Esdras Juarez-Hernandez, Brando Perez Esparza, Huzaifa Rampurawala, Brent Carlton, Surej Ravikumar, Carlos Nieva, Sungwon Kim, Hyung-Jin Lee, Amir Sammak, Giordano Scappucci, Menno Veldhorst, Fabio Sebastiano, Masoud Babaie, Stefano Pellerano, Edoardo Charbon and Lieven M. K. Vandersypen

Ultralow contact resistance between semimetal and monolayer semiconductors pp. 211-217

Pin-Chun Shen, Cong Su, Yuxuan Lin, Ang-Sheng Chou, Chao-Ching Cheng, Ji-Hoon Park, Ming-Hui Chiu, Ang-Yu Lu, Hao-Ling Tang, Mohammad Mahdi Tavakoli, Gregory Pitner, Xiang Ji, Zhengyang Cai, Nannan Mao, Jiangtao Wang, Vincent Tung, Ju Li, Jeffrey Bokor, Alex Zettl, Chih-I Wu, Tomás Palacios, Lain-Jong Li and Jing Kong

A dynamic stability design strategy for lithium metal solid state batteries pp. 218-222

Luhan Ye and Xin Li

Skeletal editing through direct nitrogen deletion of secondary amines pp. 223-227

Sean H. Kennedy, Balu D. Dherange, Kathleen J. Berger and Mark D. Levin

Widespread six degrees Celsius cooling on land during the Last Glacial Maximum pp. 228-232

Alan M. Seltzer, Jessica Ng, Werner Aeschbach, Rolf Kipfer, Justin T. Kulongoski, Jeffrey P. Severinghaus and Martin Stute

Ubiquitous atmospheric production of organic acids mediated by cloud droplets pp. 233-237

B. Franco, T. Blumenstock, C. Cho, L. Clarisse, C. Clerbaux, P.-F. Coheur, M. De Mazière, I. De Smedt, H.-P. Dorn, T. Emmerichs, H. Fuchs, G. Gkatzelis, D. W. T. Griffith, S. Gromov, J. W. Hannigan, F. Hase, T. Hohaus, N. Jones, A. Kerkweg, A. Kiendler-Scharr, E. Lutsch, E. Mahieu, A. Novelli, I. Ortega, C. Paton-Walsh, M. Pommier, A. Pozzer, D. Reimer, S. Rosanka, R. Sander, M. Schneider, K. Strong, R. Tillmann, M. Van Roozendael, L. Vereecken, C. Vigouroux, A. Wahner and D. Taraborrelli

Genome-wide enhancer maps link risk variants to disease genes pp. 238-243

Joseph Nasser, Drew T. Bergman, Charles P. Fulco, Philine Guckelberger, Benjamin R. Doughty, Tejal A. Patwardhan, Thouis R. Jones, Tung H. Nguyen, Jacob C. Ulirsch, Fritz Lekschas, Kristy Mualim, Heini M. Natri, Elle M. Weeks, Glen Munson, Michael Kane, Helen Y. Kang, Ang Cui, John P. Ray, Thomas M. Eisenhaure, Ryan L. Collins, Kushal Dey, Hanspeter Pfister, Alkes L. Price, Charles B. Epstein, Anshul Kundaje, Ramnik J. Xavier, Mark J. Daly, Hailiang Huang, Hilary K. Finucane, Nir Hacohen, Eric S. Lander and Jesse M. Engreitz

Coupling of activity, metabolism and behaviour across the Drosophila brain pp. 244-248

Kevin Mann, Stephane Deny, Surya Ganguli and Thomas R. Clandinin

High-performance brain-to-text communication via handwriting pp. 249-254

Francis R. Willett, Donald T. Avansino, Leigh R. Hochberg, Jaimie M. Henderson and Krishna V. Shenoy

Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy pp. 255-260

Sandro Mesquita, Zachary Papadopoulos, Taitea Dykstra, Logan Brase, Fabiana Geraldo Farias, Morgan Wall, Hong Jiang, Chinnappa Dilip Kodira, Kalil Alves Lima, Jasmin Herz, Antoine Louveau, Dylan H. Goldman, Andrea Francesca Salvador, Suna Onengut-Gumuscu, Emily Farber, Nisha Dabhi, Tatiana Kennedy, Mary Grace Milam, Wendy Baker, Igor Smirnov, Stephen S. Rich, Bruno A. Benitez, Celeste M. Karch, Richard J. Perrin, Martin Farlow, Jasmeer P. Chhatwal, David M. Holtzman, Carlos Cruchaga, Oscar Harari and Jonathan Kipnis

C. difficile exploits a host metabolite produced during toxin-mediated disease pp. 261-265

Kali M. Pruss and Justin L. Sonnenburg

Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England pp. 266-269

Erik Volz, Swapnil Mishra, Meera Chand, Jeffrey C. Barrett, Robert Johnson, Lily Geidelberg, Wes R. Hinsley, Daniel J. Laydon, Gavin Dabrera, Áine O’Toole, Robert Amato, Manon Ragonnet-Cronin, Ian Harrison, Ben Jackson, Cristina V. Ariani, Olivia Boyd, Nicholas J. Loman, John T. McCrone, Sónia Gonçalves, David Jorgensen, Richard Myers, Verity Hill, David K. Jackson, Katy Gaythorpe, Natalie Groves, John Sillitoe, Dominic P. Kwiatkowski, Seth Flaxman, Oliver Ratmann, Samir Bhatt, Susan Hopkins, Axel Gandy, Andrew Rambaut and Neil M. Ferguson

Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7 pp. 270-274

Nicholas G. Davies, Christopher I. Jarvis, W. John Edmunds, Nicholas P. Jewell, Karla Diaz-Ordaz and Ruth H. Keogh

A myeloid–stromal niche and gp130 rescue in NOD2-driven Crohn’s disease pp. 275-281

Shikha Nayar, Joshua K. Morrison, Mamta Giri, Kyle Gettler, Ling-shiang Chuang, Laura A. Walker, Huaibin M. Ko, Ephraim Kenigsberg, Subra Kugathasan, Miriam Merad, Jaime Chu and Judy H. Cho

Cell-programmed nutrient partitioning in the tumour microenvironment pp. 282-288

Bradley I. Reinfeld, Matthew Z. Madden, Melissa M. Wolf, Anna Chytil, Jackie E. Bader, Andrew R. Patterson, Ayaka Sugiura, Allison S. Cohen, Ahmed Ali, Brian T. Do, Alexander Muir, Caroline A. Lewis, Rachel A. Hongo, Kirsten L. Young, Rachel E. Brown, Vera M. Todd, Tessa Huffstater, Abin Abraham, Richard T. O’Neil, Matthew H. Wilson, Fuxue Xin, M. Noor Tantawy, W. David Merryman, Rachelle W. Johnson, Christopher S. Williams, Emily F. Mason, Frank M. Mason, Katherine E. Beckermann, Matthew G. Heiden, H. Charles Manning, Jeffrey C. Rathmell and W. Kimryn Rathmell

HP1 drives de novo 3D genome reorganization in early Drosophila embryos pp. 289-293

Fides Zenk, Yinxiu Zhan, Pavel Kos, Eva Löser, Nazerke Atinbayeva, Melanie Schächtle, Guido Tiana, Luca Giorgetti and Nicola Iovino

Structural basis of long-range to short-range synaptic transition in NHEJ pp. 294-298

Siyu Chen, Linda Lee, Tasmin Naila, Susan Fishbain, Annie Wang, Alan E. Tomkinson, Susan P. Lees-Miller and Yuan He

How to blow the whistle on an academic bully pp. 299-301

Virginia Gewin

Smartphone science: apps test and track infectious diseases pp. 302-303

Sandeep Ravindran

A deep-rooted appreciation for the health benefits of plants pp. 306-306

James Mitchell Crow

2021, volume 593, articles 7857

Author Correction: Rebuilding marine life pp. E1-E2

Carlos M. Duarte, Susana Agusti, Edward Barbier, Gregory L. Britten, Juan Carlos Castilla, Jean-Pierre Gattuso, Robinson W. Fulweiler, Terry P. Hughes, Nancy Knowlton, Catherine E. Lovelock, Heike K. Lotze, Milica Predragovic, Elvira Poloczanska, Callum Roberts and Boris Worm

Author Correction: Synthesis and breakdown of universal metabolic precursors promoted by iron pp. E3-E3

Kamila B. Muchowska, Sreejith J. Varma and Joseph Moran

Author Correction: Slower decay of landfalling hurricanes in a warming world pp. E4-E11

Lin Li and Pinaki Chakraborty

Indian government should heed its scientists on COVID pp. 9-9

T. V. Padma

‘We are being ignored’: Brazil’s researchers blame anti-science government for devastating COVID surge pp. 15-16

Luke Taylor

Malaria vaccine shows promise — now come tougher trials pp. 17-17

Heidi Ledford

What’s next for physics’ standard model? Muon results throw theories into confusion pp. 18-19

Davide Castelvecchi

How a historic funding boom might transform the US National Science Foundation pp. 19-20

Ariana Remmel

Key COVID research hit by cut to UK foreign-aid budget pp. 20-21

Holly Else

One million coronavirus sequences: popular genome site hits mega milestone pp. 21-21

Amy Maxmen

Microplastics are everywhere — but are they harmful? pp. 22-25

XiaoZhi Lim

Fevers are plaguing the oceans — and climate change is making them worse pp. 26-28

Giuliana Viglione

How Navy money changed the course of sea science pp. 29-30

Ann Finkbeiner

Scientific success by numbers pp. 30-31

Cassidy R. Sugimoto

Cooperative AI: machines must learn to find common ground pp. 33-36

Allan Dafoe, Yoram Bachrach, Gillian Hadfield, Eric Horvitz, Kate Larson and Thore Graepel

Five principles for scientists on social media pp. 37-37

Marcel Bogers

Brazil: video inspires young women to work in solar energy pp. 37-37

Aline Cristiane Pan, Aline Kirsten Vidal de Oliveira, Kathlen Schneider, Natália Chaves and Izete Zanesco

Fix databases that fail with two surnames pp. 37-37

Jorge Mira Pérez and M. Carmen Parafita Couto

African swine fever ravaging Borneo’s wild pigs pp. 37-37

Robert M. Ewers, Senthilvel K. S. S. Nathan and Peter A. K. Lee

A child’s grave is the earliest known burial site in Africa pp. 39-40

Louise Humphrey

Black hole jets bent by magnetic fields pp. 40-41

Joydeep Bagchi

African forest maps reveal areas vulnerable to the effects of climate change pp. 42-43

Marion Pfeifer and Deo D. Shirima

Prediction for magnetic moment of the muon informs a test of the standard model of particle physics pp. 44-45

Harvey B. Meyer

Jets from MRC 0600-399 bent by magnetic fields in the cluster Abell 3376 pp. 47-50

James O. Chibueze, Haruka Sakemi, Takumi Ohmura, Mami Machida, Hiroki Akamatsu, Takuya Akahori, Hiroyuki Nakanishi, Viral Parekh, Ruby Rooyen and Tsutomu T. Takeuchi

Leading hadronic contribution to the muon magnetic moment from lattice QCD pp. 51-55

Sz. Borsanyi, Z. Fodor, J. N. Guenther, C. Hoelbling, S. D. Katz, L. Lellouch, T. Lippert, K. Miura, L. Parato, K. K. Szabo, F. Stokes, B. C. Toth, Cs. Torok and L. Varnhorst

Rashba valleys and quantum Hall states in few-layer black arsenic pp. 56-60

Feng Sheng, Chenqiang Hua, Man Cheng, Jie Hu, Xikang Sun, Qian Tao, Hengzhe Lu, Yunhao Lu, Mianzeng Zhong, Kenji Watanabe, Takashi Taniguchi, Qinglin Xia, Zhu-An Xu and Yi Zheng

Polypeptide organic radical batteries pp. 61-66

Tan P. Nguyen, Alexandra D. Easley, Nari Kang, Sarosh Khan, Soon-Mi Lim, Yohannes H. Rezenom, Shaoyang Wang, David K. Tran, Jingwei Fan, Rachel A. Letteri, Xun He, Lu Su, Cheng-Han Yu, Jodie L. Lutkenhaus and Karen L. Wooley

Correlative operando microscopy of oxygen evolution electrocatalysts pp. 67-73

J. Tyler Mefford, Andrew R. Akbashev, Minkyung Kang, Cameron L. Bentley, William E. Gent, Haitao D. Deng, Daan Hein Alsem, Young-Sang Yu, Norman J. Salmon, David A. Shapiro, Patrick R. Unwin and William C. Chueh

Projected land ice contributions to twenty-first-century sea level rise pp. 74-82

Tamsin L. Edwards, Sophie Nowicki, Ben Marzeion, Regine Hock, Heiko Goelzer, Hélène Seroussi, Nicolas C. Jourdain, Donald A. Slater, Fiona E. Turner, Christopher J. Smith, Christine M. McKenna, Erika Simon, Ayako Abe-Ouchi, Jonathan M. Gregory, Eric Larour, William H. Lipscomb, Antony J. Payne, Andrew Shepherd, Cécile Agosta, Patrick Alexander, Torsten Albrecht, Brian Anderson, Xylar Asay-Davis, Andy Aschwanden, Alice Barthel, Andrew Bliss, Reinhard Calov, Christopher Chambers, Nicolas Champollion, Youngmin Choi, Richard Cullather, Joshua Cuzzone, Christophe Dumas, Denis Felikson, Xavier Fettweis, Koji Fujita, Benjamin K. Galton-Fenzi, Rupert Gladstone, Nicholas R. Golledge, Ralf Greve, Tore Hattermann, Matthew J. Hoffman, Angelika Humbert, Matthias Huss, Philippe Huybrechts, Walter Immerzeel, Thomas Kleiner, Philip Kraaijenbrink, Sébastien Clec’h, Victoria Lee, Gunter R. Leguy, Christopher M. Little, Daniel P. Lowry, Jan-Hendrik Malles, Daniel F. Martin, Fabien Maussion, Mathieu Morlighem, James F. O’Neill, Isabel Nias, Frank Pattyn, Tyler Pelle, Stephen F. Price, Aurélien Quiquet, Valentina Radić, Ronja Reese, David R. Rounce, Martin Rückamp, Akiko Sakai, Courtney Shafer, Nicole-Jeanne Schlegel, Sarah Shannon, Robin S. Smith, Fiammetta Straneo, Sainan Sun, Lev Tarasov, Luke D. Trusel, Jonas Breedam, Roderik Wal, Michiel Broeke, Ricarda Winkelmann, Harry Zekollari, Chen Zhao, Tong Zhang and Thomas Zwinger

The Paris Climate Agreement and future sea-level rise from Antarctica pp. 83-89

Robert M. DeConto, David Pollard, Richard B. Alley, Isabella Velicogna, Edward Gasson, Natalya Gomez, Shaina Sadai, Alan Condron, Daniel M. Gilford, Erica L. Ashe, Robert Kopp, Dawei Li and Andrea Dutton

Unveiling African rainforest composition and vulnerability to global change pp. 90-94

Maxime Réjou-Méchain, Frédéric Mortier, Jean-François Bastin, Guillaume Cornu, Nicolas Barbier, Nicolas Bayol, Fabrice Bénédet, Xavier Bry, Gilles Dauby, Vincent Deblauwe, Jean-Louis Doucet, Charles Doumenge, Adeline Fayolle, Claude Garcia, Jean-Paul Kibambe Lubamba, Jean-Joël Loumeto, Alfred Ngomanda, Pierre Ploton, Bonaventure Sonké, Catherine Trottier, Ruppert Vimal, Olga Yongo, Raphaël Pélissier and Sylvie Gourlet-Fleury

Earliest known human burial in Africa pp. 95-100

María Martinón-Torres, Francesco d’Errico, Elena Santos, Ana Álvaro Gallo, Noel Amano, William Archer, Simon J. Armitage, Juan Luis Arsuaga, José María Bermúdez de Castro, James Blinkhorn, Alison Crowther, Katerina Douka, Stéphan Dubernet, Patrick Faulkner, Pilar Fernández-Colón, Nikos Kourampas, Jorge González García, David Larreina, François-Xavier Bourdonnec, George MacLeod, Laura Martín-Francés, Diyendo Massilani, Julio Mercader, Jennifer M. Miller, Emmanuel Ndiema, Belén Notario, Africa Pitarch Martí, Mary E. Prendergast, Alain Queffelec, Solange Rigaud, Patrick Roberts, Mohammad Javad Shoaee, Ceri Shipton, Ian Simpson, Nicole Boivin and Michael D. Petraglia

The structure, function and evolution of a complete human chromosome 8 pp. 101-107

Glennis A. Logsdon, Mitchell R. Vollger, PingHsun Hsieh, Yafei Mao, Mikhail A. Liskovykh, Sergey Koren, Sergey Nurk, Ludovica Mercuri, Philip C. Dishuck, Arang Rhie, Leonardo G. Lima, Tatiana Dvorkina, David Porubsky, William T. Harvey, Alla Mikheenko, Andrey V. Bzikadze, Milinn Kremitzki, Tina A. Graves-Lindsay, Chirag Jain, Kendra Hoekzema, Shwetha C. Murali, Katherine M. Munson, Carl Baker, Melanie Sorensen, Alexandra M. Lewis, Urvashi Surti, Jennifer L. Gerton, Vladimir Larionov, Mario Ventura, Karen H. Miga, Adam M. Phillippy and Evan E. Eichler

Flexible scaling and persistence of social vocal communication pp. 108-113

Jingyi Chen, Jeffrey E. Markowitz, Varoth Lilascharoen, Sandra Taylor, Pete Sheurpukdi, Jason A. Keller, Jennifer R. Jensen, Byung Kook Lim, Sandeep Robert Datta and Lisa Stowers

An amygdala circuit that suppresses social engagement pp. 114-118

Jeong-Tae Kwon, Changhyeon Ryu, Hyeseung Lee, Alec Sheffield, Jingxuan Fan, Daniel H. Cho, Shivani Bigler, Heather A. Sullivan, Han Kyung Choe, Ian R. Wickersham, Myriam Heiman and Gloria B. Choi

Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis pp. 119-124

Alejandro Aguilera-Castrejon, Bernardo Oldak, Tom Shani, Nadir Ghanem, Chen Itzkovich, Sharon Slomovich, Shadi Tarazi, Jonathan Bayerl, Valeriya Chugaeva, Muneef Ayyash, Shahd Ashouokhi, Daoud Sheban, Nir Livnat, Lior Lasman, Sergey Viukov, Mirie Zerbib, Yoseph Addadi, Yoach Rais, Saifeng Cheng, Yonatan Stelzer, Hadas Keren-Shaul, Raanan Shlomo, Rada Massarwa, Noa Novershtern, Itay Maza and Jacob H. Hanna

The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase pp. 125-129

Hundeep Kaur, Roman P. Jakob, Jan K. Marzinek, Robert Green, Yu Imai, Jani Reddy Bolla, Elia Agustoni, Carol V. Robinson, Peter J. Bond, Kim Lewis, Timm Maier and Sebastian Hiller

Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7 pp. 130-135

Pengfei Wang, Manoj S. Nair, Lihong Liu, Sho Iketani, Yang Luo, Yicheng Guo, Maple Wang, Jian Yu, Baoshan Zhang, Peter D. Kwong, Barney S. Graham, John R. Mascola, Jennifer Y. Chang, Michael T. Yin, Magdalena Sobieszczyk, Christos A. Kyratsous, Lawrence Shapiro, Zizhang Sheng, Yaoxing Huang and David D. Ho

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies pp. 136-141

Dami A. Collier, Anna Marco, Isabella A. T. M. Ferreira, Bo Meng, Rawlings P. Datir, Alexandra C. Walls, Steven A. Kemp, Jessica Bassi, Dora Pinto, Chiara Silacci-Fregni, Siro Bianchi, M. Alejandra Tortorici, John Bowen, Katja Culap, Stefano Jaconi, Elisabetta Cameroni, Gyorgy Snell, Matteo S. Pizzuto, Alessandra Franzetti Pellanda, Christian Garzoni, Agostino Riva, Anne Elmer, Nathalie Kingston, Barbara Graves, Laura E. McCoy, Kenneth G. C. Smith, John R. Bradley, Nigel Temperton, Lourdes Ceron-Gutierrez, Gabriela Barcenas-Morales, William Harvey, Herbert W. Virgin, Antonio Lanzavecchia, Luca Piccoli, Rainer Doffinger, Mark Wills, David Veesler, Davide Corti and Ravindra K. Gupta

Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma pp. 142-146

Sandile Cele, Inbal Gazy, Laurelle Jackson, Shi-Hsia Hwa, Houriiyah Tegally, Gila Lustig, Jennifer Giandhari, Sureshnee Pillay, Eduan Wilkinson, Yeshnee Naidoo, Farina Karim, Yashica Ganga, Khadija Khan, Mallory Bernstein, Alejandro B. Balazs, Bernadett I. Gosnell, Willem Hanekom, Mahomed-Yunus S. Moosa, Richard J. Lessells, Tulio Oliveira and Alex Sigal

CAR directs T cell adaptation to bile acids in the small intestine pp. 147-151

Mei Lan Chen, Xiangsheng Huang, Hongtao Wang, Courtney Hegner, Yujin Liu, Jinsai Shang, Amber Eliason, Huitian Diao, HaJeung Park, Blake Frey, Guohui Wang, Sarah A. Mosure, Laura A. Solt, Douglas J. Kojetin, Alex Rodriguez-Palacios, Deborah A. Schady, Casey T. Weaver, Matthew E. Pipkin, David D. Moore and Mark S. Sundrud

Sell yourself and your science in a compelling personal statement pp. 153-155

Andy Tay

Reactive, reproducible, collaborative: computational notebooks evolve pp. 156-157

Jeffrey M. Perkel

Global virus tracker pp. 160-160

Kendall Powell