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2020, volume 583, articles 7818

Cystic fibrosis pp. S1-S1

Herb Brody

Cystic fibrosis drugs target the malformed proteins at the root of the disease pp. S2-S4

Sarah DeWeerdt

A simple test could extend cystic-fibrosis treatments to those left behind pp. S5-S5

Steven M. Rowe

In utero intervention to stem the damage of cystic fibrosis pp. S6-S7

Elie Dolgin

Bacteria-eating viruses could provide a route to stability in cystic fibrosis pp. S8-S9

Elizabeth Svoboda

The gender gap in cystic fibrosis pp. S10-S11

Natalie Healey

Gene therapy could offer an inclusive cure for cystic fibrosis pp. S12-S14

Roxanne Khamsi

The coronavirus pandemic has forced rapid changes in care protocols for cystic fibrosis pp. S15-S15

Jane Davies

Living, breathing proof pp. S16-S16

Roxanne Khamsi

How much protein function needs to be restored in cystic fibrosis? pp. S17-S17

Benjamin Plackett

Research round-up: Cystic fibrosis pp. S18-S19

Liam Drew

Author Correction: Structure of human GABAB receptor in an inactive state pp. E29-E29

Jinseo Park, Ziao Fu, Aurel Frangaj, Jonathan Liu, Lidia Mosyak, Tong Shen, Vesna N. Slavkovich, Kimberly M. Ray, Jaume Taura, Baohua Cao, Yong Geng, Hao Zuo, Yongjun Kou, Robert Grassucci, Shaoxia Chen, Zheng Liu, Xin Lin, Justin P. Williams, William J. Rice, Edward T. Eng, Rick K. Huang, Rajesh K. Soni, Brian Kloss, Zhiheng Yu, Jonathan A. Javitch, Wayne A. Hendrickson, Paul A. Slesinger, Matthias Quick, Joseph Graziano, Hongtao Yu, Oliver Fiehn, Oliver B. Clarke, Joachim Frank and Qing R. Fan

Author Correction: The Apostasia genome and the evolution of orchids pp. E30-E30

Guo-Qiang Zhang, Ke-Wei Liu, Zhen Li, Rolf Lohaus, Yu-Yun Hsiao, Shan-Ce Niu, Jie-Yu Wang, Yao-Cheng Lin, Qing Xu, Li-Jun Chen, Kouki Yoshida, Sumire Fujiwara, Zhi-Wen Wang, Yong-Qiang Zhang, Nobutaka Mitsuda, Meina Wang, Guo-Hui Liu, Lorenzo Pecoraro, Hui-Xia Huang, Xin-Ju Xiao, Min Lin, Xin-Yi Wu, Wan-Lin Wu, You-Yi Chen, Song-Bin Chang, Shingo Sakamoto, Masaru Ohme-Takagi, Masafumi Yagi, Si-Jin Zeng, Ching-Yu Shen, Chuan-Ming Yeh, Yi-Bo Luo, Wen-Chieh Tsai, Yves Peer and Zhong-Jian Liu

Publisher Correction: A planet within the debris disk around the pre-main-sequence star AU Microscopii pp. E31-E31

Peter Plavchan, Thomas Barclay, Jonathan Gagné, Peter Gao, Bryson Cale, William Matzko, Diana Dragomir, Sam Quinn, Dax Feliz, Keivan Stassun, Ian J. M. Crossfield, David A. Berardo, David W. Latham, Ben Tieu, Guillem Anglada-Escudé, George Ricker, Roland Vanderspek, Sara Seager, Joshua N. Winn, Jon M. Jenkins, Stephen Rinehart, Akshata Krishnamurthy, Scott Dynes, John Doty, Fred Adams, Dennis A. Afanasev, Chas Beichman, Mike Bottom, Brendan P. Bowler, Carolyn Brinkworth, Carolyn J. Brown, Andrew Cancino, David R. Ciardi, Mark Clampin, Jake T. Clark, Karen Collins, Cassy Davison, Daniel Foreman-Mackey, Elise Furlan, Eric J. Gaidos, Claire Geneser, Frank Giddens, Emily Gilbert, Ryan Hall, Coel Hellier, Todd Henry, Jonathan Horner, Andrew W. Howard, Chelsea Huang, Joseph Huber, Stephen R. Kane, Matthew Kenworthy, John Kielkopf, David Kipping, Chris Klenke, Ethan Kruse, Natasha Latouf, Patrick Lowrance, Bertrand Mennesson, Matthew Mengel, Sean M. Mills, Tim Morton, Norio Narita, Elisabeth Newton, America Nishimoto, Jack Okumura, Enric Palle, Joshua Pepper, Elisa V. Quintana, Aki Roberge, Veronica Roccatagliata, Joshua E. Schlieder, Angelle Tanner, Johanna Teske, C. G. Tinney, Andrew Vanderburg, Kaspar Braun, Bernie Walp, Jason Wang, Sharon Xuesong Wang, Denise Weigand, Russel White, Robert A. Wittenmyer, Duncan J. Wright, Allison Youngblood, Hui Zhang and Perri Zilberman

Publisher Correction: Imaging single glycans pp. E32-E32

X. Wu, M. Delbianco, K. Anggara, T. Michnowicz, A. Pardo-Vargas, P. Bharate, S. Sen, M. Pristl, S. Rauschenbach, U. Schlickum, S. Abb, P. H. Seeberger and K. Kern

Too many senior white academics still resist recognizing racism pp. 661-661

Namandjé Bumpus

Ebola prepared these countries for coronavirus — but now even they are floundering pp. 667-668

Amy Maxmen

Coronavirus vaccines leap through safety trials — but which will work is anybody’s guess pp. 669-670

Ewen Callaway

Controversial cave discoveries suggest humans reached Americas much earlier than thought pp. 670-671

Colin Barras

China’s successful launch of Mars mission seals global era in deep-space exploration pp. 671-671

Smriti Mallapaty

‘Our epidemic could exceed a million cases’ — South Africa’s top coronavirus adviser pp. 672-672

Linda Nordling

Pluto’s dark side spills its secrets — including hints of a hidden ocean pp. 674-678

Shannon Hall

Vaccines stop diseases safely — why all the suspicion? pp. 680-681

Joan Donovan

Equity: a mathematician shares her solution pp. 681-682

Jory C. Lerback

COVID-19: save lives with open intellectual-property licences pp. 683-683

Jorge L. Contreras, Michael Eisen and Diane M. Peters

#StopPandemicBias: scientists, share your privilege pp. 683-683

Ulrike Endesfelder, Dirk Pflüger and Timo de Wolff

Make Black history core to degrees, tie tenure to anti-racism efforts pp. 683-683

Cheryl Gore-Felton, Christina Tara Khan and Jacqueline Njenga

UK funders learn from COVID-19 ‘white-water ride’ pp. 683-683

Louise Wood and Fiona M. Watt

Expanded ENCODE delivers invaluable genomic encyclopedia pp. 685-686

Chung-Chau Hon and Piero Carninci

The Phoenix stellar stream rose from the ashes of an ancient star cluster pp. 687-688

J. M. Diederik Kruijssen

An umbrella approach to test lung cancer therapies pp. 688-689

Alexander Drilon and Matthew D. Hellmann

Growth-mediated sensing of long-term cold in plants pp. 690-691

Hiroyuki Iida and Ari Pekka Mähönen

Perspectives on ENCODE pp. 693-698

Michael P. Snyder, Thomas R. Gingeras, Jill E. Moore, Zhiping Weng, Mark B. Gerstein, Bing Ren, Ross C. Hardison, John A. Stamatoyannopoulos, Brenton R. Graveley, Elise A. Feingold, Michael J. Pazin, Michael Pagan, Daniel A. Gilchrist, Benjamin C. Hitz, J. Michael Cherry, Bradley E. Bernstein, Eric M. Mendenhall, Daniel R. Zerbino, Adam Frankish, Paul Flicek and Richard M. Myers

Expanded encyclopaedias of DNA elements in the human and mouse genomes pp. 699-710

Jill E. Moore, Michael J. Purcaro, Henry E. Pratt, Charles B. Epstein, Noam Shoresh, Jessika Adrian, Trupti Kawli, Carrie A. Davis, Alexander Dobin, Rajinder Kaul, Jessica Halow, Eric L. Nostrand, Peter Freese, David U. Gorkin, Yin Shen, Yupeng He, Mark Mackiewicz, Florencia Pauli-Behn, Brian A. Williams, Ali Mortazavi, Cheryl A. Keller, Xiao-Ou Zhang, Shaimae I. Elhajjajy, Jack Huey, Diane E. Dickel, Valentina Snetkova, Xintao Wei, Xiaofeng Wang, Juan Carlos Rivera-Mulia, Joel Rozowsky, Jing Zhang, Surya B. Chhetri, Jialing Zhang, Alec Victorsen, Kevin P. White, Axel Visel, Gene W. Yeo, Christopher B. Burge, Eric Lécuyer, David M. Gilbert, Job Dekker, John Rinn, Eric M. Mendenhall, Joseph R. Ecker, Manolis Kellis, Robert J. Klein, William S. Noble, Anshul Kundaje, Roderic Guigó, Peggy J. Farnham, J. Michael Cherry, Richard M. Myers, Bing Ren, Brenton R. Graveley, Mark B. Gerstein, Len A. Pennacchio, Michael P. Snyder, Bradley E. Bernstein, Barbara Wold, Ross C. Hardison, Thomas R. Gingeras, John A. Stamatoyannopoulos and Zhiping Weng

A large-scale binding and functional map of human RNA-binding proteins pp. 711-719

Eric L. Nostrand, Peter Freese, Gabriel A. Pratt, Xiaofeng Wang, Xintao Wei, Rui Xiao, Steven M. Blue, Jia-Yu Chen, Neal A. L. Cody, Daniel Dominguez, Sara Olson, Balaji Sundararaman, Lijun Zhan, Cassandra Bazile, Louis Philip Benoit Bouvrette, Julie Bergalet, Michael O. Duff, Keri E. Garcia, Chelsea Gelboin-Burkhart, Myles Hochman, Nicole J. Lambert, Hairi Li, Michael P. McGurk, Thai B. Nguyen, Tsultrim Palden, Ines Rabano, Shashank Sathe, Rebecca Stanton, Amanda Su, Ruth Wang, Brian A. Yee, Bing Zhou, Ashley L. Louie, Stefan Aigner, Xiang-Dong Fu, Eric Lécuyer, Christopher B. Burge, Brenton R. Graveley and Gene W. Yeo

Occupancy maps of 208 chromatin-associated proteins in one human cell type pp. 720-728

E. Christopher Partridge, Surya B. Chhetri, Jeremy W. Prokop, Ryne C. Ramaker, Camden S. Jansen, Say-Tar Goh, Mark Mackiewicz, Kimberly M. Newberry, Laurel A. Brandsmeier, Sarah K. Meadows, C. Luke Messer, Andrew A. Hardigan, Candice J. Coppola, Emma C. Dean, Shan Jiang, Daniel Savic, Ali Mortazavi, Barbara J. Wold, Richard M. Myers and Eric M. Mendenhall

Global reference mapping of human transcription factor footprints pp. 729-736

Jeff Vierstra, John Lazar, Richard Sandstrom, Jessica Halow, Kristen Lee, Daniel Bates, Morgan Diegel, Douglas Dunn, Fidencio Neri, Eric Haugen, Eric Rynes, Alex Reynolds, Jemma Nelson, Audra Johnson, Mark Frerker, Michael Buckley, Rajinder Kaul, Wouter Meuleman and John A. Stamatoyannopoulos

Landscape of cohesin-mediated chromatin loops in the human genome pp. 737-743

Fabian Grubert, Rohith Srivas, Damek V Spacek, Maya Kasowski, Mariana Ruiz-Velasco, Nasa Sinnott-Armstrong, Peyton Greenside, Anil Narasimha, Qing Liu, Benjamin Geller, Akshay Sanghi, Michael Kulik, Silin Sa, Marlene Rabinovitch, Anshul Kundaje, Stephen Dalton, Judith B. Zaugg and Michael Snyder

An atlas of dynamic chromatin landscapes in mouse fetal development pp. 744-751

David U. Gorkin, Iros Barozzi, Yuan Zhao, Yanxiao Zhang, Hui Huang, Ah Young Lee, Bin Li, Joshua Chiou, Andre Wildberg, Bo Ding, Bo Zhang, Mengchi Wang, J. Seth Strattan, Jean M. Davidson, Yunjiang Qiu, Veena Afzal, Jennifer A. Akiyama, Ingrid Plajzer-Frick, Catherine S. Novak, Momoe Kato, Tyler H. Garvin, Quan T. Pham, Anne N. Harrington, Brandon J. Mannion, Elizabeth A. Lee, Yoko Fukuda-Yuzawa, Yupeng He, Sebastian Preissl, Sora Chee, Jee Yun Han, Brian A. Williams, Diane Trout, Henry Amrhein, Hongbo Yang, J. Michael Cherry, Wei Wang, Kyle Gaulton, Joseph R. Ecker, Yin Shen, Diane E. Dickel, Axel Visel, Len A. Pennacchio and Bing Ren

Spatiotemporal DNA methylome dynamics of the developing mouse fetus pp. 752-759

Yupeng He, Manoj Hariharan, David U. Gorkin, Diane E. Dickel, Chongyuan Luo, Rosa G. Castanon, Joseph R. Nery, Ah Young Lee, Yuan Zhao, Hui Huang, Brian A. Williams, Diane Trout, Henry Amrhein, Rongxin Fang, Huaming Chen, Bin Li, Axel Visel, Len A. Pennacchio, Bing Ren and Joseph R. Ecker

The changing mouse embryo transcriptome at whole tissue and single-cell resolution pp. 760-767

Peng He, Brian A. Williams, Diane Trout, Georgi K. Marinov, Henry Amrhein, Libera Berghella, Say-Tar Goh, Ingrid Plajzer-Frick, Veena Afzal, Len A. Pennacchio, Diane E. Dickel, Axel Visel, Bing Ren, Ross C. Hardison, Yu Zhang and Barbara J. Wold

The tidal remnant of an unusually metal-poor globular cluster pp. 768-770

Zhen Wan, Geraint F. Lewis, Ting S. Li, Jeffrey D. Simpson, Sarah L. Martell, Daniel B. Zucker, Jeremy R. Mould, Denis Erkal, Andrew B. Pace, Dougal Mackey, Alexander P. Ji, Sergey E. Koposov, Kyler Kuehn, Nora Shipp, Eduardo Balbinot, Joss Bland-Hawthorn, Andrew R. Casey, Gary S. Costa, Prajwal Kafle, Sanjib Sharma and Gayandhi M. Silva

Night-time measurements of astronomical seeing at Dome A in Antarctica pp. 771-774

Bin Ma, Zhaohui Shang, Yi Hu, Keliang Hu, Yongjiang Wang, Xu Yang, Michael C. B. Ashley, Paul Hickson and Peng Jiang

Waveguide quantum electrodynamics with superconducting artificial giant atoms pp. 775-779

Bharath Kannan, Max J. Ruckriegel, Daniel L. Campbell, Anton Frisk Kockum, Jochen Braumüller, David K. Kim, Morten Kjaergaard, Philip Krantz, Alexander Melville, Bethany M. Niedzielski, Antti Vepsäläinen, Roni Winik, Jonilyn L. Yoder, Franco Nori, Terry P. Orlando, Simon Gustavsson and William D. Oliver

Deep strong light–matter coupling in plasmonic nanoparticle crystals pp. 780-784

Niclas S. Mueller, Yu Okamura, Bruno G. M. Vieira, Sabrina Juergensen, Holger Lange, Eduardo B. Barros, Florian Schulz and Stephanie Reich

Coherent many-body exciton in van der Waals antiferromagnet NiPS3 pp. 785-789

Soonmin Kang, Kangwon Kim, Beom Hyun Kim, Jonghyeon Kim, Kyung Ik Sim, Jae-Ung Lee, Sungmin Lee, Kisoo Park, Seokhwan Yun, Taehun Kim, Abhishek Nag, Andrew Walters, Mirian Garcia-Fernandez, Jiemin Li, Laurent Chapon, Ke-Jin Zhou, Young-Woo Son, Jae Hoon Kim, Hyeonsik Cheong and Je-Geun Park

A fabrication process for flexible single-crystal perovskite devices pp. 790-795

Yusheng Lei, Yimu Chen, Ruiqi Zhang, Yuheng Li, Qizhang Yan, Seunghyun Lee, Yugang Yu, Hsinhan Tsai, Woojin Choi, Kaiping Wang, Yanqi Luo, Yue Gu, Xinran Zheng, Chunfeng Wang, Chonghe Wang, Hongjie Hu, Yang Li, Baiyan Qi, Muyang Lin, Zhuorui Zhang, Shadi A. Dayeh, Matt Pharr, David P. Fenning, Yu-Hwa Lo, Jian Luo, Kesong Yang, Jinkyoung Yoo, Wanyi Nie and Sheng Xu

North Atlantic climate far more predictable than models imply pp. 796-800

D. M. Smith, A. A. Scaife, R. Eade, P. Athanasiadis, A. Bellucci, I. Bethke, R. Bilbao, L. F. Borchert, L.-P. Caron, F. Counillon, G. Danabasoglu, T. Delworth, F. J. Doblas-Reyes, N. J. Dunstone, V. Estella-Perez, S. Flavoni, L. Hermanson, N. Keenlyside, V. Kharin, M. Kimoto, W. J. Merryfield, J. Mignot, T. Mochizuki, K. Modali, P.-A. Monerie, W. A. Müller, D. Nicolí, P. Ortega, K. Pankatz, H. Pohlmann, J. Robson, P. Ruggieri, R. Sospedra-Alfonso, D. Swingedouw, Y. Wang, S. Wild, S. Yeager, X. Yang and L. Zhang

Global status and conservation potential of reef sharks pp. 801-806

M. Aaron MacNeil, Demian D. Chapman, Michelle Heupel, Colin A. Simpfendorfer, Michael Heithaus, Mark Meekan, Euan Harvey, Jordan Goetze, Jeremy Kiszka, Mark E. Bond, Leanne M. Currey-Randall, Conrad W. Speed, C. Samantha Sherman, Matthew J. Rees, Vinay Udyawer, Kathryn I. Flowers, Gina Clementi, Jasmine Valentin-Albanese, Taylor Gorham, M. Shiham Adam, Khadeeja Ali, Fabián Pina-Amargós, Jorge A. Angulo-Valdés, Jacob Asher, Laura García Barcia, Océane Beaufort, Cecilie Benjamin, Anthony T. F. Bernard, Michael L. Berumen, Stacy Bierwagen, Erika Bonnema, Rosalind M. K. Bown, Darcy Bradley, Edd Brooks, J. Jed Brown, Dayne Buddo, Patrick Burke, Camila Cáceres, Diego Cardeñosa, Jeffrey C. Carrier, Jennifer E. Caselle, Venkatesh Charloo, Thomas Claverie, Eric Clua, Jesse E. M. Cochran, Neil Cook, Jessica Cramp, Brooke D’Alberto, Martin Graaf, Mareike Dornhege, Andy Estep, Lanya Fanovich, Naomi F. Farabaugh, Daniel Fernando, Anna L. Flam, Camilla Floros, Virginia Fourqurean, Ricardo Garla, Kirk Gastrich, Lachlan George, Rory Graham, Tristan Guttridge, Royale S. Hardenstine, Stephen Heck, Aaron C. Henderson, Heidi Hertler, Robert Hueter, Mohini Johnson, Stacy Jupiter, Devanshi Kasana, Steven T. Kessel, Benedict Kiilu, Taratu Kirata, Baraka Kuguru, Fabian Kyne, Tim Langlois, Elodie J. I. Lédée, Steve Lindfield, Andrea Luna-Acosta, Jade Maggs, B. Mabel Manjaji-Matsumoto, Andrea Marshall, Philip Matich, Erin McCombs, Dianne McLean, Llewelyn Meggs, Stephen Moore, Sushmita Mukherji, Ryan Murray, Muslimin Kaimuddin, Stephen J. Newman, Josep Nogués, Clay Obota, Owen O’Shea, Kennedy Osuka, Yannis P. Papastamatiou, Nishan Perera, Bradley Peterson, Alessandro Ponzo, Andhika Prasetyo, L. M. Sjamsul Quamar, Jessica Quinlan, Alexei Ruiz-Abierno, Enric Sala, Melita Samoilys, Michelle Schärer-Umpierre, Audrey Schlaff, Nikola Simpson, Adam N. H. Smith, Lauren Sparks, Akshay Tanna, Rubén Torres, Michael J. Travers, Maurits Zinnicq Bergmann, Laurent Vigliola, Juney Ward, Alexandra M. Watts, Colin Wen, Elizabeth Whitman, Aaron J. Wirsing, Aljoscha Wothke, Esteban Zarza-Gonzâlez and Joshua E. Cinner

The National Lung Matrix Trial of personalized therapy in lung cancer pp. 807-812

Gary Middleton, Peter Fletcher, Sanjay Popat, Joshua Savage, Yvonne Summers, Alastair Greystoke, David Gilligan, Judith Cave, Noelle O’Rourke, Alison Brewster, Elizabeth Toy, James Spicer, Pooja Jain, Adam Dangoor, Melanie Mackean, Martin Forster, Amanda Farley, Dee Wherton, Manita Mehmi, Rowena Sharpe, Tara C. Mills, Maria Antonietta Cerone, Timothy A. Yap, Thomas B. K. Watkins, Emilia Lim, Charles Swanton and Lucinda Billingham

Two dynamically distinct circuits drive inhibition in the sensory thalamus pp. 813-818

Rosa I. Martinez-Garcia, Bettina Voelcker, Julia B. Zaltsman, Saundra L. Patrick, Tanya R. Stevens, Barry W. Connors and Scott J. Cruikshank

Distinct subnetworks of the thalamic reticular nucleus pp. 819-824

Yinqing Li, Violeta G. Lopez-Huerta, Xian Adiconis, Kirsten Levandowski, Soonwook Choi, Sean K. Simmons, Mario A. Arias-Garcia, Baolin Guo, Annie Y. Yao, Timothy R. Blosser, Ralf D. Wimmer, Tomomi Aida, Alexander Atamian, Tina Naik, Xuyun Sun, Dasheng Bi, Diya Malhotra, Cynthia C. Hession, Reut Shema, Marcos Gomes, Taibo Li, Eunjin Hwang, Alexandra Krol, Monika Kowalczyk, João Peça, Gang Pan, Michael M. Halassa, Joshua Z. Levin, Zhanyan Fu and Guoping Feng

Temperature-dependent growth contributes to long-term cold sensing pp. 825-829

Yusheng Zhao, Rea L. Antoniou-Kourounioti, Grant Calder, Caroline Dean and Martin Howard

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice pp. 830-833

Linlin Bao, Wei Deng, Baoying Huang, Hong Gao, Jiangning Liu, Lili Ren, Qiang Wei, Pin Yu, Yanfeng Xu, Feifei Qi, Yajin Qu, Fengdi Li, Qi Lv, Wenling Wang, Jing Xue, Shuran Gong, Mingya Liu, Guanpeng Wang, Shunyi Wang, Zhiqi Song, Linna Zhao, Peipei Liu, Li Zhao, Fei Ye, Huijuan Wang, Weimin Zhou, Na Zhu, Wei Zhen, Haisheng Yu, Xiaojuan Zhang, Li Guo, Lan Chen, Conghui Wang, Ying Wang, Xinming Wang, Yan Xiao, Qiangming Sun, Hongqi Liu, Fanli Zhu, Chunxia Ma, Lingmei Yan, Mengli Yang, Jun Han, Wenbo Xu, Wenjie Tan, Xiaozhong Peng, Qi Jin, Guizhen Wu and Chuan Qin

Pathogenesis and transmission of SARS-CoV-2 in golden hamsters pp. 834-838

Sin Fun Sia, Li-Meng Yan, Alex W. H. Chin, Kevin Fung, Ka-Tim Choy, Alvina Y. L. Wong, Prathanporn Kaewpreedee, Ranawaka A. P. M. Perera, Leo L. M. Poon, John M. Nicholls, Malik Peiris and Hui-Ling Yen

A leptin–BDNF pathway regulating sympathetic innervation of adipose tissue pp. 839-844

Putianqi Wang, Ken H. Loh, Michelle Wu, Donald A. Morgan, Marc Schneeberger, Xiaofei Yu, Jingyi Chi, Christin Kosse, Damian Kim, Kamal Rahmouni, Paul Cohen and Jeffrey Friedman

Signalling input from divergent pathways subverts B cell transformation pp. 845-851

Lai N. Chan, Mark A. Murakami, Mark E. Robinson, Rebecca Caeser, Teresa Sadras, Jaewoong Lee, Kadriye Nehir Cosgun, Kohei Kume, Vishal Khairnar, Gang Xiao, Mohamed A. Ahmed, Eamon Aghania, Gauri Deb, Christian Hurtz, Seyedmehdi Shojaee, Chao Hong, Petri Pölönen, Matthew A. Nix, Zhengshan Chen, Chun Wei Chen, Jianjun Chen, Andreas Vogt, Merja Heinäniemi, Olli Lohi, Arun P. Wiita, Shai Izraeli, Huimin Geng, David M. Weinstock and Markus Müschen

Histone H3.3 phosphorylation amplifies stimulation-induced transcription pp. 852-857

Anja Armache, Shuang Yang, Alexia Martínez de Paz, Lexi E. Robbins, Ceyda Durmaz, Jin Q. Cheong, Arjun Ravishankar, Andrew W. Daman, Dughan J. Ahimovic, Thaís Klevorn, Yuan Yue, Tanja Arslan, Shu Lin, Tanya Panchenko, Joel Hrit, Miao Wang, Samuel Thudium, Benjamin A. Garcia, Erica Korb, Karim-Jean Armache, Scott B. Rothbart, Sandra B. Hake, C. David Allis, Haitao Li and Steven Z. Josefowicz

DNA surface exploration and operator bypassing during target search pp. 858-861

Emil Marklund, Brad Oosten, Guanzhong Mao, Elias Amselem, Kalle Kipper, Anton Sabantsev, Andrew Emmerich, Daniel Globisch, Xuan Zheng, Laura C. Lehmann, Otto G. Berg, Magnus Johansson, Johan Elf and Sebastian Deindl

Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor pp. 862-866

Yang Lee, Tony Warne, Rony Nehmé, Shubhi Pandey, Hemlata Dwivedi-Agnihotri, Madhu Chaturvedi, Patricia C. Edwards, Javier García-Nafría, Andrew G. W. Leslie, Arun K. Shukla and Christopher G. Tate

The career cost of COVID-19 to female researchers, and how science should respond pp. 867-869

Virginia Gewin

Measuring ripples in the curvature of space-time pp. 872-872

Amber Dance

2020, volume 583, articles 7817

Author Correction: Elpistostege and the origin of the vertebrate hand pp. E28-E28

Richard Cloutier, Alice M. Clement, Michael S. Y. Lee, Roxanne Noël, Isabelle Béchard, Vincent Roy and John A. Long

Publishers: let transgender scholars correct their names pp. 493-493

Theresa Jean Tanenbaum

Arab world’s first Mars probe takes to the skies pp. 499-500

Elizabeth Gibney

Mystery over Universe’s expansion deepens with fresh data pp. 500-501

Davide Castelvecchi

Row over Africa’s largest dam in danger of escalating, warn scientists pp. 501-502

Antoaneta Roussi

Pandemic speeds largest test yet of universal basic income pp. 502-503

Carrie Arnold

The mathematical strategy that could transform coronavirus testing pp. 504-505

Smriti Mallapaty

The explosion of new coronavirus tests that could help to end the pandemic pp. 506-509

Giorgia Guglielmi

Mounting evidence suggests coronavirus is airborne — but health advice has not caught up pp. 510-513

Dyani Lewis

Fraud, bias, negligence and hype in the lab — a rogues’ gallery pp. 515-516

Fiona Fidler

What we owe to fire, home working vs the driverless car, and survival of the unfittest: Books in brief pp. 516-516

Andrew Robinson

The best time to argue about what a replication means? Before you do it pp. 518-520

Brian A. Nosek and Timothy M. Errington

Mitochondrial genome editing gets precise pp. 521-522

Magomet Aushev and Mary Herbert

Five centuries of human observation reveal Europe’s flood history pp. 522-524

Francis Ludlow and Rhonda McGovern

Native South Americans were early inhabitants of Polynesia pp. 524-525

Paul Wallin

How lactate links cannabis to social behaviour pp. 526-527

Pierre J. Magistretti

Measurement of the time spent by a tunnelling atom within the barrier region pp. 529-532

Ramón Ramos, David Spierings, Isabelle Racicot and Aephraim M. Steinberg

Quantum-limit Chern topological magnetism in TbMn6Sn6 pp. 533-536

Jia-Xin Yin, Wenlong Ma, Tyler A. Cochran, Xitong Xu, Songtian S. Zhang, Hung-Ju Tien, Nana Shumiya, Guangming Cheng, Kun Jiang, Biao Lian, Zhida Song, Guoqing Chang, Ilya Belopolski, Daniel Multer, Maksim Litskevich, Zi-Jia Cheng, Xian P. Yang, Bianca Swidler, Huibin Zhou, Hsin Lin, Titus Neupert, Ziqiang Wang, Nan Yao, Tay-Rong Chang, Shuang Jia and M. Zahid Hasan

Imaging viscous flow of the Dirac fluid in graphene pp. 537-541

Mark J. H. Ku, Tony X. Zhou, Qing Li, Young J. Shin, Jing K. Shi, Claire Burch, Laurel E. Anderson, Andrew T. Pierce, Yonglong Xie, Assaf Hamo, Uri Vool, Huiliang Zhang, Francesco Casola, Takashi Taniguchi, Kenji Watanabe, Michael M. Fogler, Philip Kim, Amir Yacoby and Ronald L. Walsworth

Cleavable comonomers enable degradable, recyclable thermoset plastics pp. 542-547

Peyton Shieh, Wenxu Zhang, Keith E. L. Husted, Samantha L. Kristufek, Boya Xiong, David J. Lundberg, Jet Lem, David Veysset, Yuchen Sun, Keith A. Nelson, Desiree L. Plata and Jeremiah A. Johnson

Desymmetrization of difluoromethylene groups by C–F bond activation pp. 548-553

Trevor W. Butcher, Jonathan L. Yang, Willi M. Amberg, Nicholas B. Watkins, Natalie D. Wilkinson and John F. Hartwig

Ice retreat in Wilkes Basin of East Antarctica during a warm interglacial pp. 554-559

T. Blackburn, G. H. Edwards, S. Tulaczyk, M. Scudder, G. Piccione, B. Hallet, N. McLean, J. C. Zachos, B. Cheney and J. T. Babbe

Current European flood-rich period exceptional compared with past 500 years pp. 560-566

Günter Blöschl, Andrea Kiss, Alberto Viglione, Mariano Barriendos, Oliver Böhm, Rudolf Brázdil, Denis Coeur, Gaston Demarée, Maria Carmen Llasat, Neil Macdonald, Dag Retsö, Lars Roald, Petra Schmocker-Fackel, Inês Amorim, Monika Bělínová, Gerardo Benito, Chiara Bertolin, Dario Camuffo, Daniel Cornel, Radosław Doktor, Líbor Elleder, Silvia Enzi, João Carlos Garcia, Rüdiger Glaser, Julia Hall, Klaus Haslinger, Michael Hofstätter, Jürgen Komma, Danuta Limanówka, David Lun, Andrei Panin, Juraj Parajka, Hrvoje Petrić, Fernando S. Rodrigo, Christian Rohr, Johannes Schönbein, Lothar Schulte, Luís Pedro Silva, Willem H. J. Toonen, Peter Valent, Jürgen Waser and Oliver Wetter

Antarctica’s wilderness fails to capture continent’s biodiversity pp. 567-571

Rachel I. Leihy, Bernard W. T. Coetzee, Fraser Morgan, Ben Raymond, Justine D. Shaw, Aleks Terauds, Kees Bastmeijer and Steven L. Chown

Native American gene flow into Polynesia predating Easter Island settlement pp. 572-577

Alexander G. Ioannidis, Javier Blanco-Portillo, Karla Sandoval, Erika Hagelberg, Juan Francisco Miquel-Poblete, J. Víctor Moreno-Mayar, Juan Esteban Rodríguez-Rodríguez, Consuelo D. Quinto-Cortés, Kathryn Auckland, Tom Parks, Kathryn Robson, Adrian V. S. Hill, María C. Avila-Arcos, Alexandra Sockell, Julian R. Homburger, Genevieve L. Wojcik, Kathleen C. Barnes, Luisa Herrera, Soledad Berríos, Mónica Acuña, Elena Llop, Celeste Eng, Scott Huntsman, Esteban G. Burchard, Christopher R. Gignoux, Lucía Cifuentes, Ricardo A. Verdugo, Mauricio Moraga, Alexander J. Mentzer, Carlos D. Bustamante and Andrés Moreno-Estrada

Six reference-quality genomes reveal evolution of bat adaptations pp. 578-584

David Jebb, Zixia Huang, Martin Pippel, Graham M. Hughes, Ksenia Lavrichenko, Paolo Devanna, Sylke Winkler, Lars S. Jermiin, Emilia C. Skirmuntt, Aris Katzourakis, Lucy Burkitt-Gray, David A. Ray, Kevin A. M. Sullivan, Juliana G. Roscito, Bogdan M. Kirilenko, Liliana M. Dávalos, Angelique P. Corthals, Megan L. Power, Gareth Jones, Roger D. Ransome, Dina K. N. Dechmann, Andrea G. Locatelli, Sébastien J. Puechmaille, Olivier Fedrigo, Erich D. Jarvis, Michael Hiller, Sonja C. Vernes, Eugene W. Myers and Emma C. Teeling

Single-cell lineage tracing unveils a role for TCF15 in haematopoiesis pp. 585-589

Alejo E. Rodriguez-Fraticelli, Caleb Weinreb, Shou-Wen Wang, Rosa P. Migueles, Maja Jankovic, Marc Usart, Allon M. Klein, Sally Lowell and Fernando D. Camargo

Ageing hallmarks exhibit organ-specific temporal signatures pp. 596-602

Nicholas Schaum, Benoit Lehallier, Oliver Hahn, Róbert Pálovics, Shayan Hosseinzadeh, Song E. Lee, Rene Sit, Davis P. Lee, Patricia Morán Losada, Macy E. Zardeneta, Tobias Fehlmann, James T. Webber, Aaron McGeever, Kruti Calcuttawala, Hui Zhang, Daniela Berdnik, Vidhu Mathur, Weilun Tan, Alexander Zee, Michelle Tan, Angela Oliveira Pisco, Jim Karkanias, Norma F. Neff, Andreas Keller, Spyros Darmanis, Stephen R. Quake and Tony Wyss-Coray

Glucose metabolism links astroglial mitochondria to cannabinoid effects pp. 603-608

Daniel Jimenez-Blasco, Arnau Busquets-Garcia, Etienne Hebert-Chatelain, Roman Serrat, Carlos Vicente-Gutierrez, Christina Ioannidou, Paula Gómez-Sotres, Irene Lopez-Fabuel, Monica Resch-Beusher, Eva Resel, Dorian Arnouil, Dave Saraswat, Marjorie Varilh, Astrid Cannich, Francisca Julio-Kalajzic, Itziar Bonilla-Del Río, Angeles Almeida, Nagore Puente, Svein Achicallende, Maria-Luz Lopez-Rodriguez, Charlotte Jollé, Nicole Déglon, Luc Pellerin, Charlène Josephine, Gilles Bonvento, Aude Panatier, Beat Lutz, Pier-Vincenzo Piazza, Manuel Guzmán, Luigi Bellocchio, Anne-Karine Bouzier-Sore, Pedro Grandes, Juan P. Bolaños and Giovanni Marsicano

IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy pp. 609-614

Ting Zhou, William Damsky, Orr-El Weizman, Meaghan K. McGeary, K. Patricia Hartmann, Connor E. Rosen, Suzanne Fischer, Ruaidhri Jackson, Richard A. Flavell, Jun Wang, Miguel F. Sanmamed, Marcus W. Bosenberg and Aaron M. Ring

IGF1R is an entry receptor for respiratory syncytial virus pp. 615-619

Cameron D. Griffiths, Leanne M. Bilawchuk, John E. McDonough, Kyla C. Jamieson, Farah Elawar, Yuchen Cen, Wenming Duan, Cindy Lin, Haeun Song, Jean-Laurent Casanova, Steven Ogg, Lionel Dylan Jensen, Bernard Thienpont, Anil Kumar, Tom C. Hobman, David Proud, Theo J. Moraes and David J. Marchant

Fasting-mimicking diet and hormone therapy induce breast cancer regression pp. 620-624

Irene Caffa, Vanessa Spagnolo, Claudio Vernieri, Francesca Valdemarin, Pamela Becherini, Min Wei, Sebastian Brandhorst, Chiara Zucal, Else Driehuis, Lorenzo Ferrando, Francesco Piacente, Alberto Tagliafico, Michele Cilli, Luca Mastracci, Valerio G. Vellone, Silvano Piazza, Anna Laura Cremonini, Raffaella Gradaschi, Carolina Mantero, Mario Passalacqua, Alberto Ballestrero, Gabriele Zoppoli, Michele Cea, Annalisa Arrighi, Patrizio Odetti, Fiammetta Monacelli, Giulia Salvadori, Salvatore Cortellino, Hans Clevers, Filippo Braud, Samir G. Sukkar, Alessandro Provenzani, Valter D. Longo and Alessio Nencioni

N6-methyladenine in DNA antagonizes SATB1 in early development pp. 625-630

Zheng Li, Shuai Zhao, Raman V. Nelakanti, Kaixuan Lin, Tao P. Wu, Myles H. Alderman, Cheng Guo, Pengcheng Wang, Min Zhang, Wang Min, Zongliang Jiang, Yinsheng Wang, Haitao Li and Andrew Z. Xiao

A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing pp. 631-637

Beverly Y. Mok, Marcos H. de Moraes, Jun Zeng, Dustin E. Bosch, Anna V. Kotrys, Aditya Raguram, FoSheng Hsu, Matthew C. Radey, S. Brook Peterson, Vamsi K. Mootha, Joseph D. Mougous and David R. Liu

Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping pp. 638-643

Aldema Sas-Chen, Justin M. Thomas, Donna Matzov, Masato Taoka, Kellie D. Nance, Ronit Nir, Keri M. Bryson, Ran Shachar, Geraldy L. S. Liman, Brett W. Burkhart, Supuni Thalalla Gamage, Yuko Nobe, Chloe A. Briney, Michaella J. Levy, Ryan T. Fuchs, G. Brett Robb, Jesse Hartmann, Sunny Sharma, Qishan Lin, Laurence Florens, Michael P. Washburn, Toshiaki Isobe, Thomas J. Santangelo, Moran Shalev-Benami, Jordan L. Meier and Schraga Schwartz

Seeking an ‘exit plan’ for leaving academia amid coronavirus worries pp. 645-646

Chris Woolston

Why scientists with children who have disabilities need a different career trajectory pp. 646-646

Olivier Pourret

Coronavirus vaccines get a biotech boost pp. 647-649

Amber Dance

Using robots to probe how people react to simple behaviours pp. 652-652

Josie Glausiusz

2020, volume 583, articles 7816

The ‘Radcliffe Wave’ as a Kelvin–Helmholtz instability pp. E24-E25

Robert Fleck

Author Correction: Origin of complexity in haemoglobin evolution pp. E26-E26

Arvind S. Pillai, Shane A. Chandler, Yang Liu, Anthony V. Signore, Carlos R. Cortez-Romero, Justin L. P. Benesch, Arthur Laganowsky, Jay F. Storz, Georg K. A. Hochberg and Joseph W. Thornton

Author Correction: Tunable correlated states and spin-polarized phases in twisted bilayer–bilayer graphene pp. E27-E27

Yuan Cao, Daniel Rodan-Legrain, Oriol Rubies-Bigorda, Jeong Min Park, Kenji Watanabe, Takashi Taniguchi and Pablo Jarillo-Herrero

Plug COVID-19 research gaps in detection, prevention and care pp. 333-333

Trudie Lang

California’s San Quentin prison declined free coronavirus tests and urgent advice — now it has a massive outbreak pp. 339-340

Amy Maxmen

Scientists in China say US government crackdown is harming collaborations pp. 341-342

Andrew Silver

Exclusive: US National Science Foundation reveals first details on foreign-influence investigations pp. 342-342

Andrew Silver

Scientists make precise gene edits to mitochondrial DNA for first time pp. 343-343

Heidi Ledford

Scientists call for pandemic investigations to focus on wildlife trade pp. 344-344

Smriti Mallapaty

How scientific societies are weathering the pandemic’s financial storm pp. 345-345

Diana Kwon

A guide to R — the pandemic’s misunderstood metric pp. 346-348

David Adam

How did ancient cities weather crises? pp. 349-350

Andrew Robinson

The many roads to the red planet — a memoir pp. 350-351

Alexandra Witze

Cities — try to predict superspreading hotspots for COVID-19 pp. 352-355

Roland Bouffanais and Sun Sun Lim

An analysis of ways to decarbonize conference travel after COVID-19 pp. 356-359

Milan Klöwer, Debbie Hopkins, Myles Allen and James Higham

Contact-tracing apps: contested answers to ethical questions pp. 360-360

Matthias Braun and Patrik Hummel

Public health is moot without water security pp. 360-360

Richard J. Dawson

Use AI to mine literature for policymaking pp. 360-360

Leonid Gokhberg

Coronavirus: postdoc winners need paid extensions pp. 360-360

Theo van den Broek and James Gould

Simple molecules self-assemble into the links of a nanoscale chain pp. 361-362

Guillaume De Bo

Unexpected amount of blood-borne protein enters the young brain pp. 362-363

Roeben N. Munji and Richard Daneman

Electronics tuned in twisted bilayer graphene pp. 364-365

Ronny Thomale

Hard evidence from soft fossil eggs pp. 365-366

Johan Lindgren and Benjamin P. Kear

A race to determine what drives COVID-19 severity pp. 366-368

Marios Koutsakos and Katherine Kedzierska

A subradiant optical mirror formed by a single structured atomic layer pp. 369-374

Jun Rui, David Wei, Antonio Rubio-Abadal, Simon Hollerith, Johannes Zeiher, Dan M. Stamper-Kurn, Christian Gross and Immanuel Bloch

Untying the insulating and superconducting orders in magic-angle graphene pp. 375-378

Petr Stepanov, Ipsita Das, Xiaobo Lu, Ali Fahimniya, Kenji Watanabe, Takashi Taniguchi, Frank H. L. Koppens, Johannes Lischner, Leonid Levitov and Dmitri K. Efetov

Superconductivity in metallic twisted bilayer graphene stabilized by WSe2 pp. 379-384

Harpreet Singh Arora, Robert Polski, Yiran Zhang, Alex Thomson, Youngjoon Choi, Hyunjin Kim, Zhong Lin, Ilham Zaky Wilson, Xiaodong Xu, Jiun-Haw Chu, Kenji Watanabe, Takashi Taniguchi, Jason Alicea and Stevan Nadj-Perge

Monolithic piezoelectric control of soliton microcombs pp. 385-390

Junqiu Liu, Hao Tian, Erwan Lucas, Arslan S. Raja, Grigory Lihachev, Rui Ning Wang, Jijun He, Tianyi Liu, Miles H. Anderson, Wenle Weng, Sunil A. Bhave and Tobias J. Kippenberg

Vacancy-enabled N2 activation for ammonia synthesis on an Ni-loaded catalyst pp. 391-395

Tian-Nan Ye, Sang-Won Park, Yangfan Lu, Jiang Li, Masato Sasase, Masaaki Kitano, Tomofumi Tada and Hideo Hosono

Compression of curium pyrrolidine-dithiocarbamate enhances covalency pp. 396-399

Joseph M. Sperling, Evan J. Warzecha, Cristian Celis-Barros, Dumitru-Claudiu Sergentu, Xiaoyu Wang, Bonnie E. Klamm, Cory J. Windorff, Alyssa N. Gaiser, Frankie D. White, Drake A. Beery, Alexander T. Chemey, Megan A. Whitefoot, Brian N. Long, Kenneth Hanson, Paul Kögerler, Manfred Speldrich, Eva Zurek, Jochen Autschbach and Thomas E. Albrecht-Schönzart

Self-assembled poly-catenanes from supramolecular toroidal building blocks pp. 400-405

Sougata Datta, Yasuki Kato, Seiya Higashiharaguchi, Keisuke Aratsu, Atsushi Isobe, Takuho Saito, Deepak D. Prabhu, Yuichi Kitamoto, Martin J. Hollamby, Andrew J. Smith, Robert Dalgliesh, Najet Mahmoudi, Luca Pesce, Claudio Perego, Giovanni M. Pavan and Shiki Yagai

The first dinosaur egg was soft pp. 406-410

Mark A. Norell, Jasmina Wiemann, Matteo Fabbri, Congyu Yu, Claudia A. Marsicano, Anita Moore-Nall, David J. Varricchio, Diego Pol and Darla K. Zelenitsky

A giant soft-shelled egg from the Late Cretaceous of Antarctica pp. 411-414

Lucas J. Legendre, David Rubilar-Rogers, Grace M. Musser, Sarah N. Davis, Rodrigo A. Otero, Alexander O. Vargas and Julia A. Clarke

A neurotransmitter produced by gut bacteria modulates host sensory behaviour pp. 415-420

Michael P. O’Donnell, Bennett W. Fox, Pin-Hao Chao, Frank C. Schroeder and Piali Sengupta

Sodium regulates clock time and output via an excitatory GABAergic pathway pp. 421-424

Claire Gizowski and Charles W. Bourque

Physiological blood–brain transport is impaired with age by a shift in transcytosis pp. 425-430

Andrew C. Yang, Marc Y. Stevens, Michelle B. Chen, Davis P. Lee, Daniel Stähli, David Gate, Kévin Contrepois, Winnie Chen, Tal Iram, Lichao Zhang, Ryan T. Vest, Aisling Chaney, Benoit Lehallier, Niclas Olsson, Haley Bois, Ryan Hsieh, Haley C. Cropper, Daniela Berdnik, Lulin Li, Elizabeth Y. Wang, Gavin M. Traber, Carolyn R. Bertozzi, Jian Luo, Michael P. Snyder, Joshua E. Elias, Stephen R. Quake, Michelle L. James and Tony Wyss-Coray

Single-molecule imaging of transcription dynamics in somatic stem cells pp. 431-436

Justin C. Wheat, Yehonatan Sella, Michael Willcockson, Arthur I. Skoultchi, Aviv Bergman, Robert H. Singer and Ulrich Steidl

Viral and host factors related to the clinical outcome of COVID-19 pp. 437-440

Xiaonan Zhang, Yun Tan, Yun Ling, Gang Lu, Feng Liu, Zhigang Yi, Xiaofang Jia, Min Wu, Bisheng Shi, Shuibao Xu, Jun Chen, Wei Wang, Bing Chen, Lu Jiang, Shuting Yu, Jing Lu, Jinzeng Wang, Mingzhu Xu, Zhenghong Yuan, Qin Zhang, Xinxin Zhang, Guoping Zhao, Shengyue Wang, Saijuan Chen and Hongzhou Lu

Microbiota modulate sympathetic neurons via a gut–brain circuit pp. 441-446

Paul A. Muller, Marc Schneeberger, Fanny Matheis, Putianqi Wang, Zachary Kerner, Anoj Ilanges, Kyle Pellegrino, Josefina Mármol, Tiago B. R. Castro, Munehiro Furuichi, Matthew Perkins, Wenfei Han, Arka Rao, Amanda J. Pickard, Justin R. Cross, Kenya Honda, Ivan Araujo and Daniel Mucida

A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells pp. 447-452

Rabab Nasrallah, Charlotte J. Imianowski, Lara Bossini-Castillo, Francis M. Grant, Mikail Dogan, Lindsey Placek, Lina Kozhaya, Paula Kuo, Firas Sadiyah, Sarah K. Whiteside, Maxwell R. Mumbach, Dafni Glinos, Panagiota Vardaka, Carly E. Whyte, Teresa Lozano, Toshitsugu Fujita, Hodaka Fujii, Adrian Liston, Simon Andrews, Adeline Cozzani, Jie Yang, Suman Mitra, Enrico Lugli, Howard Y. Chang, Derya Unutmaz, Gosia Trynka and Rahul Roychoudhuri

Bacterial chemolithoautotrophy via manganese oxidation pp. 453-458

Hang Yu and Jared R. Leadbetter

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing pp. 459-468

David E. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M. White, Matthew J. O’Meara, Veronica V. Rezelj, Jeffrey Z. Guo, Danielle L. Swaney, Tia A. Tummino, Ruth Hüttenhain, Robyn M. Kaake, Alicia L. Richards, Beril Tutuncuoglu, Helene Foussard, Jyoti Batra, Kelsey Haas, Maya Modak, Minkyu Kim, Paige Haas, Benjamin J. Polacco, Hannes Braberg, Jacqueline M. Fabius, Manon Eckhardt, Margaret Soucheray, Melanie J. Bennett, Merve Cakir, Michael J. McGregor, Qiongyu Li, Bjoern Meyer, Ferdinand Roesch, Thomas Vallet, Alice Mac Kain, Lisa Miorin, Elena Moreno, Zun Zar Chi Naing, Yuan Zhou, Shiming Peng, Ying Shi, Ziyang Zhang, Wenqi Shen, Ilsa T. Kirby, James E. Melnyk, John S. Chorba, Kevin Lou, Shizhong A. Dai, Inigo Barrio-Hernandez, Danish Memon, Claudia Hernandez-Armenta, Jiankun Lyu, Christopher J. P. Mathy, Tina Perica, Kala Bharath Pilla, Sai J. Ganesan, Daniel J. Saltzberg, Ramachandran Rakesh, Xi Liu, Sara B. Rosenthal, Lorenzo Calviello, Srivats Venkataramanan, Jose Liboy-Lugo, Yizhu Lin, Xi-Ping Huang, YongFeng Liu, Stephanie A. Wankowicz, Markus Bohn, Maliheh Safari, Fatima S. Ugur, Cassandra Koh, Nastaran Sadat Savar, Quang Dinh Tran, Djoshkun Shengjuler, Sabrina J. Fletcher, Michael C. O’Neal, Yiming Cai, Jason C. J. Chang, David J. Broadhurst, Saker Klippsten, Phillip P. Sharp, Nicole A. Wenzell, Duygu Kuzuoglu-Ozturk, Hao-Yuan Wang, Raphael Trenker, Janet M. Young, Devin A. Cavero, Joseph Hiatt, Theodore L. Roth, Ujjwal Rathore, Advait Subramanian, Julia Noack, Mathieu Hubert, Robert M. Stroud, Alan D. Frankel, Oren S. Rosenberg, Kliment A. Verba, David A. Agard, Melanie Ott, Michael Emerman, Natalia Jura, Mark Zastrow, Eric Verdin, Alan Ashworth, Olivier Schwartz, Christophe d’Enfert, Shaeri Mukherjee, Matt Jacobson, Harmit S. Malik, Danica G. Fujimori, Trey Ideker, Charles S. Craik, Stephen N. Floor, James S. Fraser, John D. Gross, Andrej Sali, Bryan L. Roth, Davide Ruggero, Jack Taunton, Tanja Kortemme, Pedro Beltrao, Marco Vignuzzi, Adolfo García-Sastre, Kevan M. Shokat, Brian K. Shoichet and Nevan J. Krogan

Proteomics of SARS-CoV-2-infected host cells reveals therapy targets pp. 469-472

Denisa Bojkova, Kevin Klann, Benjamin Koch, Marek Widera, David Krause, Sandra Ciesek, Jindrich Cinatl and Christian Münch

Structure of a nascent membrane protein as it folds on the BAM complex pp. 473-478

David Tomasek, Shaun Rawson, James Lee, Joseph S. Wzorek, Stephen C. Harrison, Zongli Li and Daniel Kahne

The time tax put on scientists of colour pp. 479-481

Virginia Gewin

Remote controller pp. 484-484

Virginia Gewin

2020, volume 583, articles 7815

In vivo quantification of mitochondrial membrane potential pp. E17-E18

Nathaniel M. Alpert, Matthieu Pelletier-Galarneau, Yoann Petibon, Marc D. Normandin and Georges El Fakhri

Reply to: In vivo quantification of mitochondrial membrane potential pp. E19-E20

Milica Momcilovic, Orian Shirihai, Michael P. Murphy, Carla M. Koehler, Saman Sadeghi and David B. Shackelford

Author Correction: New infant cranium from the African Miocene sheds light on ape evolution pp. E21-E21

Isaiah Nengo, Paul Tafforeau, Christopher C. Gilbert, John G. Fleagle, Ellen R. Miller, Craig Feibel, David L. Fox, Josh Feinberg, Kelsey D. Pugh, Camille Berruyer, Sara Mana, Zachary Engle and Fred Spoor

Publisher Correction: IGF1R is an entry receptor for respiratory syncytial virus pp. E22-E22

Cameron D. Griffiths, Leanne M. Bilawchuk, John E. McDonough, Kyla C. Jamieson, Farah Elawar, Yuchen Cen, Wenming Duan, Cindy Lin, Haeun Song, Jean-Laurent Casanova, Steven Ogg, Lionel Dylan Jensen, Bernard Thienpont, Anil Kumar, Tom C. Hobman, David Proud, Theo J. Moraes and David J. Marchant

Don’t ask if artificial intelligence is good or fair, ask how it shifts power pp. 169-169

Pratyusha Kalluri

Second Brazilian museum fire in two years reignites calls for reform pp. 175-176

Emiliano Rodríguez Mega

Welcome anyons! Physicists find best evidence yet for long-sought 2D structures pp. 176-177

Davide Castelvecchi

Six months of coronavirus: the mysteries scientists are still racing to solve pp. 178-179

Ewen Callaway, Heidi Ledford and Smriti Mallapaty

‘The epidemic is growing very rapidly’: Indian government adviser fears coronavirus crisis will worsen pp. 180-180

Priyanka Pulla

Former Harvard researcher who sexually harassed postdoc sparks turmoil at Italian institute pp. 182-182

Alison Abbott

Countdown to Mars: three daring missions take aim at the red planet pp. 184-188

Alexandra Witze, Smriti Mallapaty and Elizabeth Gibney

How a small Arab nation built a Mars mission from scratch in six years pp. 190-193

Elizabeth Gibney

Women are most affected by pandemics — lessons from past outbreaks pp. 194-198

Clare Wenham, Julia Smith, Sara E. Davies, Huiyun Feng, Karen A. Grépin, Sophie Harman, Asha Herten-Crabb and Rosemary Morgan

Reset Sustainable Development Goals for a pandemic world pp. 198-201

Robin Naidoo and Brendan Fisher

US visa changes leave postdocs like us in limbo pp. 202-202

M. Arslan Ahmed, Amir H. Behbahani, Adrian Brückner, Caroline J. Charpentier, Livia H. Morais, Stewart Mallory and Allan-Hermann Pool

Legacy of a 100-year-old climate model pp. 202-202

Marco Romano and Bruce Rubidge

Deconstruct racism in medicine — from training to clinical trials pp. 202-202

Talia H. Swartz and Boghuma Titanji

Fight prejudice at all levels: from airports to conferences pp. 202-202

César Marín

Going back in time for an antibody to fight COVID-19 pp. 203-204

Gary R. Whittaker and Susan Daniel

Removal of atmospheric CO2 by rock weathering holds promise for mitigating climate change pp. 204-205

Johannes Lehmann and Angela Possinger

An antiviral response beyond immune cells pp. 206-207

Tomás Gomes and Sarah A. Teichmann

Strands of evidence about cancer evolution pp. 207-209

Trevor A. Graham and Sarah E. McClelland

Asymmetric mass ratios for bright double neutron-star mergers pp. 211-214

R. D. Ferdman, P. C. C. Freire, B. B. P. Perera, N. Pol, F. Camilo, S. Chatterjee, J. M. Cordes, F. Crawford, J. W. T. Hessels, V. M. Kaspi, M. A. McLaughlin, E. Parent, I. H. Stairs and J. Leeuwen

Tunable correlated states and spin-polarized phases in twisted bilayer–bilayer graphene pp. 215-220

Yuan Cao, Daniel Rodan-Legrain, Oriol Rubies-Bigorda, Jeong Min Park, Kenji Watanabe, Takashi Taniguchi and Pablo Jarillo-Herrero

Tunable spin-polarized correlated states in twisted double bilayer graphene pp. 221-225

Xiaomeng Liu, Zeyu Hao, Eslam Khalaf, Jong Yeon Lee, Yuval Ronen, Hyobin Yoo, Danial Haei Najafabadi, Kenji Watanabe, Takashi Taniguchi, Ashvin Vishwanath and Philip Kim

Large-scale integration of artificial atoms in hybrid photonic circuits pp. 226-231

Noel H. Wan, Tsung-Ju Lu, Kevin C. Chen, Michael P. Walsh, Matthew E. Trusheim, Lorenzo De Santis, Eric A. Bersin, Isaac B. Harris, Sara L. Mouradian, Ian R. Christen, Edward S. Bielejec and Dirk Englund

Coherent control of a surface structural phase transition pp. 232-236

Jan Gerrit Horstmann, Hannes Böckmann, Bareld Wit, Felix Kurtz, Gero Storeck and Claus Ropers

A mobile robotic chemist pp. 237-241

Benjamin Burger, Phillip M. Maffettone, Vladimir V. Gusev, Catherine M. Aitchison, Yang Bai, Xiaoyan Wang, Xiaobo Li, Ben M. Alston, Buyi Li, Rob Clowes, Nicola Rankin, Brandon Harris, Reiner Sebastian Sprick and Andrew I. Cooper

Potential for large-scale CO2 removal via enhanced rock weathering with croplands pp. 242-248

David J. Beerling, Euripides P. Kantzas, Mark R. Lomas, Peter Wade, Rafael M. Eufrasio, Phil Renforth, Binoy Sarkar, M. Grace Andrews, Rachael H. James, Christopher R. Pearce, Jean-Francois Mercure, Hector Pollitt, Philip B. Holden, Neil R. Edwards, Madhu Khanna, Lenny Koh, Shaun Quegan, Nick F. Pidgeon, Ivan A. Janssens, James Hansen and Steven A. Banwart

A Cambrian crown annelid reconciles phylogenomics and the fossil record pp. 249-252

Hong Chen, Luke A. Parry, Jakob Vinther, Dayou Zhai, Xianguang Hou and Xiaoya Ma

Structure and flexibility in cortical representations of odour space pp. 253-258

Stan L. Pashkovski, Giuliano Iurilli, David Brann, Daniel Chicharro, Kristen Drummey, Kevin M. Franks, Stefano Panzeri and Sandeep Robert Datta

Insights into variation in meiosis from 31,228 human sperm genomes pp. 259-264

Avery Davis Bell, Curtis J. Mello, James Nemesh, Sara A. Brumbaugh, Alec Wysoker and Steven A. McCarroll

Pervasive lesion segregation shapes cancer genome evolution pp. 265-270

Sarah J. Aitken, Craig J. Anderson, Frances Connor, Oriol Pich, Vasavi Sundaram, Christine Feig, Tim F. Rayner, Margus Lukk, Stuart Aitken, Juliet Luft, Elissavet Kentepozidou, Claudia Arnedo-Pac, Sjoerd V. Beentjes, Susan E. Davies, Ruben M. Drews, Ailith Ewing, Vera B. Kaiser, Ava Khamseh, Erika López-Arribillaga, Aisling M. Redmond, Javier Santoyo-Lopez, Inés Sentís, Lana Talmane, Andrew D. Yates, Colin A. Semple, Núria López-Bigas, Paul Flicek, Duncan T. Odom and Martin S. Taylor

Extensive signal integration by the phytohormone protein network pp. 271-276

Melina Altmann, Stefan Altmann, Patricia A. Rodriguez, Benjamin Weller, Lena Elorduy Vergara, Julius Palme, Nora Marín- de la Rosa, Mayra Sauer, Marion Wenig, José Antonio Villaécija-Aguilar, Jennifer Sales, Chung-Wen Lin, Ramakrishnan Pandiarajan, Veronika Young, Alexandra Strobel, Lisa Gross, Samy Carbonnel, Karl G. Kugler, Antoni Garcia-Molina, George W. Bassel, Claudia Falter, Klaus F. X. Mayer, Caroline Gutjahr, A. Corina Vlot, Erwin Grill and Pascal Falter-Braun

Transcriptional regulation of strigolactone signalling in Arabidopsis pp. 277-281

Lei Wang, Bing Wang, Hong Yu, Hongyan Guo, Tao Lin, Liquan Kou, Anqi Wang, Ning Shao, Haiyan Ma, Guosheng Xiong, Xiaoqiang Li, Jun Yang, Jinfang Chu and Jiayang Li

Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins pp. 282-285

Tommy Tsan-Yuk Lam, Na Jia, Ya-Wei Zhang, Marcus Ho-Hin Shum, Jia-Fu Jiang, Hua-Chen Zhu, Yi-Gang Tong, Yong-Xia Shi, Xue-Bing Ni, Yun-Shi Liao, Wen-Juan Li, Bao-Gui Jiang, Wei Wei, Ting-Ting Yuan, Kui Zheng, Xiao-Ming Cui, Jie Li, Guang-Qian Pei, Xin Qiang, William Yiu-Man Cheung, Lian-Feng Li, Fang-Fang Sun, Si Qin, Ji-Cheng Huang, Gabriel M. Leung, Edward C. Holmes, Yan-Ling Hu, Yi Guan and Wu-Chun Cao

Isolation of SARS-CoV-2-related coronavirus from Malayan pangolins pp. 286-289

Kangpeng Xiao, Junqiong Zhai, Yaoyu Feng, Niu Zhou, Xu Zhang, Jie-Jian Zou, Na Li, Yaqiong Guo, Xiaobing Li, Xuejuan Shen, Zhipeng Zhang, Fanfan Shu, Wanyi Huang, Yu Li, Ziding Zhang, Rui-Ai Chen, Ya-Jiang Wu, Shi-Ming Peng, Mian Huang, Wei-Jun Xie, Qin-Hui Cai, Fang-Hui Hou, Wu Chen, Lihua Xiao and Yongyi Shen

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody pp. 290-295

Dora Pinto, Young-Jun Park, Martina Beltramello, Alexandra C. Walls, M. Alejandra Tortorici, Siro Bianchi, Stefano Jaconi, Katja Culap, Fabrizia Zatta, Anna De Marco, Alessia Peter, Barbara Guarino, Roberto Spreafico, Elisabetta Cameroni, James Brett Case, Rita E. Chen, Colin Havenar-Daughton, Gyorgy Snell, Amalio Telenti, Herbert W. Virgin, Antonio Lanzavecchia, Michael S. Diamond, Katja Fink, David Veesler and Davide Corti

Structural cells are key regulators of organ-specific immune responses pp. 296-302

Thomas Krausgruber, Nikolaus Fortelny, Victoria Fife-Gernedl, Martin Senekowitsch, Linda C. Schuster, Alexander Lercher, Amelie Nemc, Christian Schmidl, André F. Rendeiro, Andreas Bergthaler and Christoph Bock

Systematic quantitative analysis of ribosome inventory during nutrient stress pp. 303-309

Heeseon An, Alban Ordureau, Maria Körner, Joao A. Paulo and J. Wade Harper

Molecular architecture of the human 17S U2 snRNP pp. 310-313

Zhenwei Zhang, Cindy L. Will, Karl Bertram, Olexandr Dybkov, Klaus Hartmuth, Dmitry E. Agafonov, Romina Hofele, Henning Urlaub, Berthold Kastner, Reinhard Lührmann and Holger Stark

Femtosecond-to-millisecond structural changes in a light-driven sodium pump pp. 314-318

Petr Skopintsev, David Ehrenberg, Tobias Weinert, Daniel James, Rajiv K. Kar, Philip J. M. Johnson, Dmitry Ozerov, Antonia Furrer, Isabelle Martiel, Florian Dworkowski, Karol Nass, Gregor Knopp, Claudio Cirelli, Christopher Arrell, Dardan Gashi, Sandra Mous, Maximilian Wranik, Thomas Gruhl, Demet Kekilli, Steffen Brünle, Xavier Deupi, Gebhard F. X. Schertler, Roger M. Benoit, Valerie Panneels, Przemyslaw Nogly, Igor Schapiro, Christopher Milne, Joachim Heberle and Jörg Standfuss

What Black scientists want from colleagues and their institutions pp. 319-322

Virginia Gewin

Gearing up for a ‘monumental’ mission to Mars pp. 324-324

Amber Dance

2020, volume 583, articles 7814

Transformation of naked mole-rat cells pp. E1-E7

Fazal Hadi, Yavuz Kulaberoglu, Kyren A. Lazarus, Karsten Bach, Rosemary Ugur, Paul Beattie, Ewan St John Smith and Walid T. Khaled

Reply to: Transformation of naked mole-rat cells pp. E8-E13

Jing Zhao, Xiao Tian, Yabing Zhu, Zhihui Zhang, Elena Rydkina, Yongxian Yuan, Hongyun Zhang, Bhaskar Roy, Adam Cornwell, Eviatar Nevo, Xiaoxiao Shang, Runyue Huang, Karsten Kristiansen, Andrei Seluanov, Xiaodong Fang and Vera Gorbunova

The Himalaya should be a nature reserve pp. 9-9

Maharaj K. Pandit

Quantum computing: how conditions created by the COVID-19 shutdown are delivering ‘the best data we have ever seen’ pp. 10-10

Christopher Monroe

Author Correction: Potential circadian effects on translational failure for neuroprotection pp. E14-E14

Elga Esposito, Wenlu Li, Emiri T. Mandeville, Ji-Hyun Park, Ikbal Şencan, Shuzhen Guo, Jingfei Shi, Jing Lan, Janice Lee, Kazuhide Hayakawa, Sava Sakadžić, Xunming Ji and Eng H. Lo

Mini organs reveal how the coronavirus ravages the body pp. 15-16

Smriti Mallapaty

Author Correction: A naturally occurring antiviral ribonucleotide encoded by the human genome pp. E15-E15

Anthony S. Gizzi, Tyler L. Grove, Jamie J. Arnold, Joyce Jose, Rohit K. Jangra, Scott J. Garforth, Quan Du, Sean M. Cahill, Natalya G. Dulyaninova, James D. Love, Kartik Chandran, Anne R. Bresnick, Craig E. Cameron and Steven C. Almo

Mounting clues suggest the coronavirus might trigger diabetes pp. 16-17

Smriti Mallapaty

CRISPR gene editing in human embryos wreaks chromosomal mayhem pp. 17-18

Heidi Ledford

Trump to suspend new visas for foreign scholars pp. 19-19

Nidhi Subbaraman and Alexandra Witze

Neutrinos reveal final secret of Sun’s nuclear fusion pp. 20-21

Davide Castelvecchi

NIH’s new sexual-harassment rules are still too weak, say critics pp. 21-21

Nidhi Subbaraman

What the data say about police brutality and racial bias — and which reforms might work pp. 22-24

Lynne Peeples

Three extraordinary women run the gauntlet of science — a documentary pp. 25-26

Alexandra Witze

Drugs, money and misleading evidence pp. 26-28

Laura Spinney

Nerve agents: from discovery to deterrence pp. 28-29

Leiv K. Sydnes

Time to invest in global resilience pp. 30-30

Jim A. Harris, David Denyer, Simon Harwood, Graham Braithwaite, Simon Jude and Paul Jeffrey

Collage of Nature covers — a geoscientist’s take pp. 30-30

Marcia Bjornerud

Tribute to a Black professor lost to COVID-19 pp. 30-30

Sushma Reddy, Ylanda Wilhite and Matt Von Konrat

Quantum fluctuations have been shown to affect macroscopic objects pp. 31-32

Valeria Sequino and Mateusz Bawaj

Neutrophil ‘safety net’ causes cancer cells to metastasize and proliferate pp. 32-33

Emma Nolan and Ilaria Malanchi

Flipping the switch on the body’s thermoregulatory system pp. 34-35

Clifford B. Saper and Natalia L. S. Machado

Atomic forces mapped out by lasers pp. 35-36

Michael A. Sentef

T cells engineered to target senescence pp. 37-38

Verena Wagner and Jesús Gil

A remnant planetary core in the hot-Neptune desert pp. 39-42

David J. Armstrong, Théo A. Lopez, Vardan Adibekyan, Richard A. Booth, Edward M. Bryant, Karen A. Collins, Magali Deleuil, Alexandre Emsenhuber, Chelsea X. Huang, George W. King, Jorge Lillo-Box, Jack J. Lissauer, Elisabeth Matthews, Olivier Mousis, Louise D. Nielsen, Hugh Osborn, Jon Otegi, Nuno C. Santos, Sérgio G. Sousa, Keivan G. Stassun, Dimitri Veras, Carl Ziegler, Jack S. Acton, Jose M. Almenara, David R. Anderson, David Barrado, Susana C. C. Barros, Daniel Bayliss, Claudia Belardi, Francois Bouchy, César Briceño, Matteo Brogi, David J. A. Brown, Matthew R. Burleigh, Sarah L. Casewell, Alexander Chaushev, David R. Ciardi, Kevin I. Collins, Knicole D. Colón, Benjamin F. Cooke, Ian J. M. Crossfield, Rodrigo F. Díaz, Elisa Delgado Mena, Olivier D. S. Demangeon, Caroline Dorn, Xavier Dumusque, Philipp Eigmüller, Michael Fausnaugh, Pedro Figueira, Tianjun Gan, Siddharth Gandhi, Samuel Gill, Erica J. Gonzales, Michael R. Goad, Maximilian N. Günther, Ravit Helled, Saeed Hojjatpanah, Steve B. Howell, James Jackman, James S. Jenkins, Jon M. Jenkins, Eric L. N. Jensen, Grant M. Kennedy, David W. Latham, Nicholas Law, Monika Lendl, Michael Lozovsky, Andrew W. Mann, Maximiliano Moyano, James McCormac, Farzana Meru, Christoph Mordasini, Ares Osborn, Don Pollacco, Didier Queloz, Liam Raynard, George R. Ricker, Pamela Rowden, Alexandre Santerne, Joshua E. Schlieder, Sara Seager, Lizhou Sha, Thiam-Guan Tan, Rosanna H. Tilbrook, Eric Ting, Stéphane Udry, Roland Vanderspek, Christopher A. Watson, Richard G. West, Paul A. Wilson, Joshua N. Winn, Peter Wheatley, Jesus Noel Villasenor, Jose I. Vines and Zhuchang Zhan

Quantum correlations between light and the kilogram-mass mirrors of LIGO pp. 43-47

Haocun Yu, L. McCuller, M. Tse, N. Kijbunchoo, L. Barsotti and N. Mavalvala

Fluorescent bicolour sensor for low-background neutrinoless double β decay experiments pp. 48-54

Iván Rivilla, Borja Aparicio, Juan M. Bueno, David Casanova, Claire Tonnelé, Zoraida Freixa, Pablo Herrero, Celia Rogero, José I. Miranda, Rosa M. Martínez-Ojeda, Francesc Monrabal, Beñat Olave, Thomas Schäfer, Pablo Artal, David Nygren, Fernando P. Cossío and Juan J. Gómez-Cadenas

Laser picoscopy of valence electrons in solids pp. 55-59

H. Lakhotia, H. Y. Kim, M. Zhan, S. Hu, S. Meng and E. Goulielmakis

Observation of branched flow of light pp. 60-65

Anatoly Patsyk, Uri Sivan, Mordechai Segev and Miguel A. Bandres

Chemical gradients in human enamel crystallites pp. 66-71

Karen A. DeRocher, Paul J. M. Smeets, Berit H. Goodge, Michael J. Zachman, Prasanna V. Balachandran, Linus Stegbauer, Michael J. Cohen, Lyle M. Gordon, James M. Rondinelli, Lena F. Kourkoutis and Derk Joester

Abrupt increase in harvested forest area over Europe after 2015 pp. 72-77

Guido Ceccherini, Gregory Duveiller, Giacomo Grassi, Guido Lemoine, Valerio Avitabile, Roberto Pilli and Alessandro Cescatti

Revealing enigmatic mucus structures in the deep sea using DeepPIV pp. 78-82

Kakani Katija, Giancarlo Troni, Joost Daniels, Kelly Lance, Rob E. Sherlock, Alana D. Sherman and Bruce H. Robison

Mapping and characterization of structural variation in 17,795 human genomes pp. 83-89

Haley J. Abel, David E. Larson, Allison A. Regier, Colby Chiang, Indraniel Das, Krishna L. Kanchi, Ryan M. Layer, Benjamin M. Neale, William J. Salerno, Catherine Reeves, Steven Buyske, Tara C. Matise, Donna M. Muzny, Michael C. Zody, Eric S. Lander, Susan K. Dutcher, Nathan O. Stitziel and Ira M. Hall

Whole-genome sequencing of a sporadic primary immunodeficiency cohort pp. 90-95

James E. D. Thaventhiran, Hana Lango Allen, Oliver S. Burren, William Rae, Daniel Greene, Emily Staples, Zinan Zhang, James H. R. Farmery, Ilenia Simeoni, Elizabeth Rivers, Jesmeen Maimaris, Christopher J. Penkett, Jonathan Stephens, Sri V. V. Deevi, Alba Sanchis-Juan, Nicholas S. Gleadall, Moira J. Thomas, Ravishankar B. Sargur, Pavels Gordins, Helen E. Baxendale, Matthew Brown, Paul Tuijnenburg, Austen Worth, Steven Hanson, Rachel J. Linger, Matthew S. Buckland, Paula J. Rayner-Matthews, Kimberly C. Gilmour, Crina Samarghitean, Suranjith L. Seneviratne, David M. Sansom, Andy G. Lynch, Karyn Megy, Eva Ellinghaus, David Ellinghaus, Silje F. Jorgensen, Tom H. Karlsen, Kathleen E. Stirrups, Antony J. Cutler, Dinakantha S. Kumararatne, Anita Chandra, J. David M. Edgar, Archana Herwadkar, Nichola Cooper, Sofia Grigoriadou, Aarnoud P. Huissoon, Sarah Goddard, Stephen Jolles, Catharina Schuetz, Felix Boschann, Paul A. Lyons, Matthew E. Hurles, Sinisa Savic, Siobhan O. Burns, Taco W. Kuijpers, Ernest Turro, Willem H. Ouwehand, Adrian J. Thrasher and Kenneth G. C. Smith

Whole-genome sequencing of patients with rare diseases in a national health system pp. 96-102

Ernest Turro, William J. Astle, Karyn Megy, Stefan Gräf, Daniel Greene, Olga Shamardina, Hana Lango Allen, Alba Sanchis-Juan, Mattia Frontini, Chantal Thys, Jonathan Stephens, Rutendo Mapeta, Oliver S. Burren, Kate Downes, Matthias Haimel, Salih Tuna, Sri V. V. Deevi, Timothy J. Aitman, David L. Bennett, Paul Calleja, Keren Carss, Mark J. Caulfield, Patrick F. Chinnery, Peter H. Dixon, Daniel P. Gale, Roger James, Ania Koziell, Michael A. Laffan, Adam P. Levine, Eamonn R. Maher, Hugh S. Markus, Joannella Morales, Nicholas W. Morrell, Andrew D. Mumford, Elizabeth Ormondroyd, Stuart Rankin, Augusto Rendon, Sylvia Richardson, Irene Roberts, Noemi B. A. Roy, Moin A. Saleem, Kenneth G. C. Smith, Hannah Stark, Rhea Y. Y. Tan, Andreas C. Themistocleous, Adrian J. Thrasher, Hugh Watkins, Andrew R. Webster, Martin R. Wilkins, Catherine Williamson, James Whitworth, Sean Humphray, David R. Bentley, Nathalie Kingston, Neil Walker, John R. Bradley, Sofie Ashford, Christopher J. Penkett, Kathleen Freson, Kathleen E. Stirrups, F. Lucy Raymond and Willem H. Ouwehand

A map of object space in primate inferotemporal cortex pp. 103-108

Pinglei Bao, Liang She, Mason McGill and Doris Y. Tsao

A discrete neuronal circuit induces a hibernation-like state in rodents pp. 109-114

Tohru M. Takahashi, Genshiro A. Sunagawa, Shingo Soya, Manabu Abe, Katsuyasu Sakurai, Kiyomi Ishikawa, Masashi Yanagisawa, Hiroshi Hama, Emi Hasegawa, Atsushi Miyawaki, Kenji Sakimura, Masayo Takahashi and Takeshi Sakurai

Neurons that regulate mouse torpor pp. 115-121

Sinisa Hrvatin, Senmiao Sun, Oren F. Wilcox, Hanqi Yao, Aurora J. Lavin-Peter, Marcelo Cicconet, Elena G. Assad, Michaela E. Palmer, Sage Aronson, Alexander S. Banks, Eric C. Griffith and Michael E. Greenberg

Hepatic NADH reductive stress underlies common variation in metabolic traits pp. 122-126

Russell P. Goodman, Andrew L. Markhard, Hardik Shah, Rohit Sharma, Owen S. Skinner, Clary B. Clish, Amy Deik, Anupam Patgiri, Yu-Han H. Hsu, Ricard Masia, Hye Lim Noh, Sujin Suk, Olga Goldberger, Joel N. Hirschhorn, Gary Yellen, Jason K. Kim and Vamsi K. Mootha

Senolytic CAR T cells reverse senescence-associated pathologies pp. 127-132

Corina Amor, Judith Feucht, Josef Leibold, Yu-Jui Ho, Changyu Zhu, Direna Alonso-Curbelo, Jorge Mansilla-Soto, Jacob A. Boyer, Xiang Li, Theodoros Giavridis, Amanda Kulick, Shauna Houlihan, Ellinor Peerschke, Scott L. Friedman, Vladimir Ponomarev, Alessandra Piersigilli, Michel Sadelain and Scott W. Lowe

DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25 pp. 133-138

Linbin Yang, Qiang Liu, Xiaoqian Zhang, Xinwei Liu, Boxuan Zhou, Jianing Chen, Di Huang, Jiaqian Li, Heliang Li, Fei Chen, Jiang Liu, Yue Xing, Xueman Chen, Shicheng Su and Erwei Song

Base-pair conformational switch modulates miR-34a targeting of Sirt1 mRNA pp. 139-144

Lorenzo Baronti, Ileana Guzzetti, Parisa Ebrahimi, Sarah Friebe Sandoz, Emilie Steiner, Judith Schlagnitweit, Bastian Fromm, Luis Silva, Carolina Fontana, Alan A. Chen and Katja Petzold

Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1 pp. 145-149

Michael David Clark, Gustavo F. Contreras, Rong Shen and Eduardo Perozo

Structural transitions in influenza haemagglutinin at membrane fusion pH pp. 150-153

Donald J. Benton, Steven J. Gamblin, Peter B. Rosenthal and John J. Skehel

Retraction Note: Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation pp. 154-154

Jixiao Niu, Yang Sun, Baoen Chen, Baohui Zheng, Gopala K. Jarugumilli, Sarah R. Walker, Aaron N. Hata, Mari Mino-Kenudson, David A. Frank and Xu Wu

Coronavirus misinformation, and how scientists can help to fight it pp. 155-156

Nic Fleming

Four tools that help researchers working in collaborations to see the big picture pp. 157-158

Julian Nowogrodzki

Restoring Notre-Dame’s ‘magical’ windows pp. 160-160

Chris Woolston