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2011, volume 477, articles 7366

Can algal uptake stop NO3− pollution? pp. E3-E3

Helen M. Baulch, Emily H. Stanley and Emily S. Bernhardt

Cardinale reply pp. E3-E4

Bradley J. Cardinale

Why animal research needs to improve pp. 511-511

Malcolm Macleod

Europe to map the human epigenome pp. 518-518

Alison Abbott

'Patent trolls' target biotechnology firms pp. 521-521

Erika Check Hayden

Aboriginal genome analysis comes to grips with ethics pp. 522-523

Ewen Callaway

A multi-billion dollar injection: Stimulus—response pp. 524-525

Colin Macilwain

Translational research: 4 ways to fix the clinical trial pp. 526-528

Heidi Ledford

Fund people not projects pp. 529-531

John P. A. Ioannidis

Time to legislate for the good life pp. 532-533

Charles Seaford

Epigenetics: Beyond face value pp. 534-535

Jonathan Weitzman

Linguistics: Tuning into translation pp. 536-536

Ellen Bialystok

Q&A: Digital diva pp. 537-537

Andrew Mitchinson

Bureaucracy savings should go to research pp. 538-538

Nicholas Graves and Adrian G. Barnett

Ireland: a strong knowledge economy pp. 538-538

Graham Love

Ireland: global links pay off pp. 538-538

Conor O'Carroll

More freedom for Turkish science pp. 538-538

Caghan Kizil

Snapshot of a signalling complex pp. 540-541

Thue W. Schwartz and Thomas P. Sakmar

Gravity tested on large scales pp. 541-543

Gary Wegner

Recognition of a unique partner pp. 543-544

Denise M. Monack

Ocean dynamics not required? pp. 544-545

Jing-Jia Luo

Heart fails without pump partner pp. 546-547

Sudha K. Shenoy and Howard A. Rockman

A dent in carbon's gold standard pp. 547-548

Matthias Cuntz

Crystal structure of the β2 adrenergic receptor–Gs protein complex pp. 549-555

Søren G. F. Rasmussen, Brian T. DeVree, Yaozhong Zou, Andrew C. Kruse, Ka Young Chung, Tong Sun Kobilka, Foon Sun Thian, Pil Seok Chae, Els Pardon, Diane Calinski, Jesper M. Mathiesen, Syed T. A. Shah, Joseph A. Lyons, Martin Caffrey, Samuel H. Gellman, Jan Steyaert, Georgios Skiniotis, William I. Weis, Roger K. Sunahara and Brian K. Kobilka

Crystal structure of nucleotide-free dynamin pp. 556-560

Katja Faelber, York Posor, Song Gao, Martin Held, Yvette Roske, Dennis Schulze, Volker Haucke, Frank Noé and Oliver Daumke

The crystal structure of dynamin pp. 561-566

Marijn G. J. Ford, Simon Jenni and Jodi Nunnari

Gravitational redshift of galaxies in clusters as predicted by general relativity pp. 567-569

Radosław Wojtak, Steen H. Hansen and Jens Hjorth

The excitation of solar-like oscillations in a δ Sct star by efficient envelope convection pp. 570-573

V. Antoci, G. Handler, T. L. Campante, A. O. Thygesen, A. Moya, T. Kallinger, D. Stello, A. Grigahcène, H. Kjeldsen, T. R. Bedding, T. Lüftinger, J. Christensen-Dalsgaard, G. Catanzaro, A. Frasca, P. De Cat, K. Uytterhoeven, H. Bruntt, G. Houdek, D. W. Kurtz, P. Lenz, A. Kaiser, J. Van Cleve, C. Allen and B. D. Clarke

High-fidelity projective read-out of a solid-state spin quantum register pp. 574-578

Lucio Robledo, Lilian Childress, Hannes Bernien, Bas Hensen, Paul F. A. Alkemade and Ronald Hanson

Interannual variability in the oxygen isotopes of atmospheric CO2 driven by El Niño pp. 579-582

Lisa R. Welp, Ralph F. Keeling, Harro A. J. Meijer, Alane F. Bollenbacher, Stephen C. Piper, Kei Yoshimura, Roger J. Francey, Colin E. Allison and Martin Wahlen

Transcriptomic analysis of avian digits reveals conserved and derived digit identities in birds pp. 583-586

Zhe Wang, Rebecca L. Young, Huiling Xue and Günter P. Wagner

The genome of the green anole lizard and a comparative analysis with birds and mammals pp. 587-591

Jessica Alföldi, Federica Di Palma, Manfred Grabherr, Christina Williams, Lesheng Kong, Evan Mauceli, Pamela Russell, Craig B. Lowe, Richard E. Glor, Jacob D. Jaffe, David A. Ray, Stephane Boissinot, Andrew M. Shedlock, Christopher Botka, Todd A. Castoe, John K. Colbourne, Matthew K. Fujita, Ricardo Godinez Moreno, Boudewijn F. ten Hallers, David Haussler, Andreas Heger, David Heiman, Daniel E. Janes, Jeremy Johnson, Pieter J. de Jong, Maxim Y. Koriabine, Marcia Lara, Peter A. Novick, Chris L. Organ, Sally E. Peach, Steven Poe, David D. Pollock, Kevin de Queiroz, Thomas Sanger, Steve Searle, Jeremy D. Smith, Zachary Smith, Ross Swofford, Jason Turner-Maier, Juli Wade, Sarah Young, Amonida Zadissa, Scott V. Edwards, Travis C. Glenn, Christopher J. Schneider, Jonathan B. Losos, Eric S. Lander, Matthew Breen, Chris P. Ponting and Kerstin Lindblad-Toh

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity pp. 592-595

Eric M. Kofoed and Russell E. Vance

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus pp. 596-600

Yue Zhao, Jieling Yang, Jianjin Shi, Yi-Nan Gong, Qiuhe Lu, Hao Xu, Liping Liu and Feng Shao

SUMO1-dependent modulation of SERCA2a in heart failure pp. 601-605

Changwon Kho, Ahyoung Lee, Dongtak Jeong, Jae Gyun Oh, Antoine H. Chaanine, Eddy Kizana, Woo Jin Park and Roger J. Hajjar

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes pp. 606-610

Tian-Peng Gu, Fan Guo, Hui Yang, Hai-Ping Wu, Gui-Fang Xu, Wei Liu, Zhi-Guo Xie, Linyu Shi, Xinyi He, Seung-gi Jin, Khursheed Iqbal, Yujiang Geno Shi, Zixin Deng, Piroska E. Szabó, Gerd P. Pfeifer, Jinsong Li and Guo-Liang Xu

Conformational changes in the G protein Gs induced by the β2 adrenergic receptor pp. 611-615

Ka Young Chung, Søren G. F. Rasmussen, Tong Liu, Sheng Li, Brian T. DeVree, Pil Seok Chae, Diane Calinski, Brian K. Kobilka, Virgil L. Woods and Roger K. Sunahara

The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase pp. 616-620

Dea Slade, Mark S. Dunstan, Eva Barkauskaite, Ria Weston, Pierre Lafite, Neil Dixon, Marijan Ahel, David Leys and Ivan Ahel

Learning tools: Visual aids pp. 621-622

Katharine Sanderson

Turning point: Rossa Chiu pp. 623-623

Virginia Gewin

Womanspace pp. 626-626

Ed Rybicki

2011, volume 477, articles 7365

Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes pp. E1-E2

Mohan Viswanathan and Leonard Guarente

China's new forests aren't as green as they seem pp. 371-371

Jianchu Xu

Fermilab faces life after the Tevatron pp. 379-379

Eugenie Samuel Reich

Pentagon rethinks bioterror effort pp. 380-381

Erika Check Hayden

Austria reinstates disgraced doctor pp. 384-384

Alison Abbott

Power of the Pentagon: The changing face of military science pp. 386-387

Sharon Weinberger

Military surveillance data: Shared intelligence pp. 388-389

Geoff Brumfiel

Bombs' hidden impact: The brain war pp. 390-393

Sharon Weinberger

Joining forces pp. 395-396

David L. Blazes and Kevin L. Russell

The world's most independent defence science advisers pp. 397-399

Ann Finkbeiner

A world of killer apps pp. 399-401

P. W. Singer

Energy: Burning desires pp. 403-403

Vaclav Smil

In retrospect: Normal Accidents pp. 404-405

Nick Pidgeon

Q&A: The virtual trainer pp. 406-406

Daniel Cressey

US pathology centre units will live on pp. 407-407

Thomas P. Baker, John M. Mateczun and Charles L. Rice

China's academic autocracy must go pp. 407-407

Nai-Zhuo Zhao

Review boards: vital to protect subjects pp. 407-407

Cami Gearhart

Make integrity key to recruitment pp. 407-407

Alfred P. Zarb

Longevity hits a roadblock pp. 410-411

David B. Lombard, Scott D. Pletcher, Carles Cantó and Johan Auwerx

Slippery when wetted pp. 412-413

Michael Nosonovsky

A yeast for all reasons pp. 413-414

Peter J. Enyeart and Andrew D. Ellington

Single electrons take the bus pp. 414-414

Takis Kontos

Endless variation most beautiful pp. 415-416

Michael Bevan

Precisely tuned antibodies nab HIV pp. 416-417

Paul R. Clapham and Shan Lu

Multiple reference genomes and transcriptomes for Arabidopsis thaliana pp. 419-423

Xiangchao Gan, Oliver Stegle, Jonas Behr, Joshua G. Steffen, Philipp Drewe, Katie L. Hildebrand, Rune Lyngsoe, Sebastian J. Schultheiss, Edward J. Osborne, Vipin T. Sreedharan, André Kahles, Regina Bohnert, Géraldine Jean, Paul Derwent, Paul Kersey, Eric J. Belfield, Nicholas P. Harberd, Eric Kemen, Christopher Toomajian, Paula X. Kover, Richard M. Clark, Gunnar Rätsch and Richard Mott

CTCF-binding elements mediate control of V(D)J recombination pp. 424-430

Chunguang Guo, Hye Suk Yoon, Andrew Franklin, Suvi Jain, Anja Ebert, Hwei-Ling Cheng, Erica Hansen, Orion Despo, Claudia Bossen, Christian Vettermann, Jamie G. Bates, Nicholas Richards, Darienne Myers, Harin Patel, Michael Gallagher, Mark S. Schlissel, Cornelis Murre, Meinrad Busslinger, Cosmas C. Giallourakis and Frederick W. Alt

A close nuclear black-hole pair in the spiral galaxy NGC 3393 pp. 431-434

G. Fabbiano, Junfeng Wang, M. Elvis and G. Risaliti

Electrons surfing on a sound wave as a platform for quantum optics with flying electrons pp. 435-438

Sylvain Hermelin, Shintaro Takada, Michihisa Yamamoto, Seigo Tarucha, Andreas D. Wieck, Laurent Saminadayar, Christopher Bäuerle and Tristan Meunier

On-demand single-electron transfer between distant quantum dots pp. 439-442

R. P. G. McNeil, M. Kataoka, C. J. B. Ford, C. H. W. Barnes, D. Anderson, G. A. C. Jones, I. Farrer and D. A. Ritchie

Bioinspired self-repairing slippery surfaces with pressure-stable omniphobicity pp. 443-447

Tak-Sing Wong, Sung Hoon Kang, Sindy K. Y. Tang, Elizabeth J. Smythe, Benjamin D. Hatton, Alison Grinthal and Joanna Aizenberg

Widespread iron-rich conditions in the mid-Proterozoic ocean pp. 448-451

Noah J. Planavsky, Peter McGoldrick, Clinton T. Scott, Chao Li, Christopher T. Reinhard, Amy E. Kelly, Xuelei Chu, Andrey Bekker, Gordon D. Love and Timothy W. Lyons

Phylogenomics reveals deep molluscan relationships pp. 452-456

Kevin M. Kocot, Johanna T. Cannon, Christiane Todt, Mathew R. Citarella, Andrea B. Kohn, Achim Meyer, Scott R. Santos, Christoffer Schander, Leonid L. Moroz, Bernhard Lieb and Kenneth M. Halanych

Antibiotic resistance is ancient pp. 457-461

Vanessa M. D’Costa, Christine E. King, Lindsay Kalan, Mariya Morar, Wilson W. L. Sung, Carsten Schwarz, Duane Froese, Grant Zazula, Fabrice Calmels, Regis Debruyne, G. Brian Golding, Hendrik N. Poinar and Gerard D. Wright

Evidence for several waves of global transmission in the seventh cholera pandemic pp. 462-465

Ankur Mutreja, Dong Wook Kim, Nicholas R. Thomson, Thomas R. Connor, Je Hee Lee, Samuel Kariuki, Nicholas J. Croucher, Seon Young Choi, Simon R. Harris, Michael Lebens, Swapan Kumar Niyogi, Eun Jin Kim, T. Ramamurthy, Jongsik Chun, James L. N. Wood, John D. Clemens, Cecil Czerkinsky, G. Balakrish Nair, Jan Holmgren, Julian Parkhill and Gordon Dougan

Broad neutralization coverage of HIV by multiple highly potent antibodies pp. 466-470

Laura M. Walker, Michael Huber, Katie J. Doores, Emilia Falkowska, Robert Pejchal, Jean-Philippe Julien, Sheng-Kai Wang, Alejandra Ramos, Po-Ying Chan-Hui, Matthew Moyle, Jennifer L. Mitcham, Phillip W. Hammond, Ole A. Olsen, Pham Phung, Steven Fling, Chi-Huey Wong, Sanjay Phogat, Terri Wrin, Melissa D. Simek, Protocol G. Principal Investigators, Wayne C. Koff, Ian A. Wilson, Dennis R. Burton and Pascal Poignard

Synthetic chromosome arms function in yeast and generate phenotypic diversity by design pp. 471-476

Jessica S. Dymond, Sarah M. Richardson, Candice E. Coombes, Timothy Babatz, Héloïse Muller, Narayana Annaluru, William J. Blake, Joy W. Schwerzmann, Junbiao Dai, Derek L. Lindstrom, Annabel C. Boeke, Daniel E. Gottschling, Srinivasan Chandrasegaran, Joel S. Bader and Jef D. Boeke

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation pp. 477-481

Jang Hyun Choi, Alexander S. Banks, Theodore M. Kamenecka, Scott A. Busby, Michael J. Chalmers, Naresh Kumar, Dana S. Kuruvilla, Youseung Shin, Yuanjun He, John B. Bruning, David P. Marciano, Michael D. Cameron, Dina Laznik, Michael J. Jurczak, Stephan C. Schürer, Dušica Vidović, Gerald I. Shulman, Bruce M. Spiegelman and Patrick R. Griffin

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila pp. 482-485

Camilla Burnett, Sara Valentini, Filipe Cabreiro, Martin Goss, Milán Somogyvári, Matthew D. Piper, Matthew Hoddinott, George L. Sutphin, Vid Leko, Joshua J. McElwee, Rafael P. Vazquez-Manrique, Anne-Marie Orfila, Daniel Ackerman, Catherine Au, Giovanna Vinti, Michèle Riesen, Ken Howard, Christian Neri, Antonio Bedalov, Matt Kaeberlein, Csaba Sőti, Linda Partridge and David Gems

Structures of the RNA-guided surveillance complex from a bacterial immune system pp. 486-489

Blake Wiedenheft, Gabriel C. Lander, Kaihong Zhou, Matthijs M. Jore, Stan J. J. Brouns, John van der Oost, Jennifer A. Doudna and Eva Nogales

Polyamine sensing by nascent ornithine decarboxylase antizyme stimulates decoding of its mRNA pp. 490-494

Leo Kurian, R. Palanimurugan, Daniela Gödderz and R. Jürgen Dohmen

Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2 pp. 495-498

Scott B. Hansen, Xiao Tao and Roderick MacKinnon

Education: Time to teach pp. 499-501

Paul Smaglik

Every girl dreams of falling in love pp. 504-504

Shelly Li

2011, volume 477, articles 7364

What's in a dream? pp. 1-1

Adam James

Check your legal position before advising others pp. 251-251

Willy Aspinall

Canadian ozone network faces axe pp. 257-258

Quirin Schiermeier

Nurse takes Royal Society's pulse pp. 258-258

Geoff Brumfiel

US plant scientists seek united front pp. 259-259

Heidi Ledford

UN targets top killers pp. 260-261

Declan Butler

Science enters desert debate pp. 262-262

Natasha Gilbert

Merit comes first pp. 263-263

Eric Hand

Scientists on trial: At fault? pp. 264-269

Stephen S. Hall

Should fracking stop? pp. 271-275

Robert W. Howarth, Anthony Ingraffea and Terry Engelder

Astronomy: Recasting the heavens pp. 276-277

Owen Gingerich

Culture: Artists in the lab pp. 278-279

Martin Kemp

Q&A: Climate-change DJ pp. 279-279

Jascha Hoffman

Review boards: all need closer scrutiny pp. 280-280

Nicholas C. Slack

South Korean energy plan is unrealistic pp. 280-280

Hyung-Man Kim

Selection for positive illusions pp. 282-283

Matthijs van Veelen and Martin A. Nowak

Six degrees of separation pp. 283-284

Alison Pidoux and Robin Allshire

Lethal volcanism pp. 285-286

Paul B. Wignall

Rough times in the Galactic countryside pp. 286-287

Curtis Struck

One protein, two healing properties pp. 287-288

Su M. Metcalfe

Mouse genomic variation and its effect on phenotypes and gene regulation pp. 289-294

Thomas M. Keane, Leo Goodstadt, Petr Danecek, Michael A. White, Kim Wong, Binnaz Yalcin, Andreas Heger, Avigail Agam, Guy Slater, Martin Goodson, Nicholas A. Furlotte, Eleazar Eskin, Christoffer Nellåker, Helen Whitley, James Cleak, Deborah Janowitz, Polinka Hernandez-Pliego, Andrew Edwards, T. Grant Belgard, Peter L. Oliver, Rebecca E. McIntyre, Amarjit Bhomra, Jérôme Nicod, Xiangchao Gan, Wei Yuan, Louise van der Weyden, Charles A. Steward, Sendu Bala, Jim Stalker, Richard Mott, Richard Durbin, Ian J. Jackson, Anne Czechanski, José Afonso Guerra-Assunção, Leah Rae Donahue, Laura G. Reinholdt, Bret A. Payseur, Chris P. Ponting, Ewan Birney, Jonathan Flint and David J. Adams

lincRNAs act in the circuitry controlling pluripotency and differentiation pp. 295-300

Mitchell Guttman, Julie Donaghey, Bryce W. Carey, Manuel Garber, Jennifer K. Grenier, Glen Munson, Geneva Young, Anne Bergstrom Lucas, Robert Ach, Laurakay Bruhn, Xiaoping Yang, Ido Amit, Alexander Meissner, Aviv Regev, John L. Rinn, David E. Root and Eric S. Lander

The Sagittarius impact as an architect of spirality and outer rings in the Milky Way pp. 301-303

Chris W. Purcell, James S. Bullock, Erik J. Tollerud, Miguel Rocha and Sukanya Chakrabarti

Geometrical enhancement of low-field magnetoresistance in silicon pp. 304-307

Caihua Wan, Xiaozhong Zhang, Xili Gao, Jimin Wang and Xinyu Tan

Overcoming lability of extremely long alkane carbon–carbon bonds through dispersion forces pp. 308-311

Peter R. Schreiner, Lesya V. Chernish, Pavel A. Gunchenko, Evgeniya Yu. Tikhonchuk, Heike Hausmann, Michael Serafin, Sabine Schlecht, Jeremy E. P. Dahl, Robert M. K. Carlson and Andrey A. Fokin

Linking mantle plumes, large igneous provinces and environmental catastrophes pp. 312-316

Stephan V. Sobolev, Alexander V. Sobolev, Dmitry V. Kuzmin, Nadezhda A. Krivolutskaya, Alexey G. Petrunin, Nicholas T. Arndt, Viktor A. Radko and Yuri R. Vasiliev

The evolution of overconfidence pp. 317-320

Dominic D. P. Johnson and James H. Fowler

Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes pp. 321-325

Patrick T. McGrath, Yifan Xu, Michael Ailion, Jennifer L. Garrison, Rebecca A. Butcher and Cornelia I. Bargmann

Sequence-based characterization of structural variation in the mouse genome pp. 326-329

Binnaz Yalcin, Kim Wong, Avigail Agam, Martin Goodson, Thomas M. Keane, Xiangchao Gan, Christoffer Nellåker, Leo Goodstadt, Jérôme Nicod, Amarjit Bhomra, Polinka Hernandez-Pliego, Helen Whitley, James Cleak, Rebekah Dutton, Deborah Janowitz, Richard Mott, David J. Adams and Jonathan Flint

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation pp. 330-334

Patrick-Simon Welz, Andy Wullaert, Katerina Vlantis, Vangelis Kondylis, Vanesa Fernández-Majada, Maria Ermolaeva, Petra Kirsch, Anja Sterner-Kock, Geert van Loo and Manolis Pasparakis

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis pp. 335-339

Claudia Günther, Eva Martini, Nadine Wittkopf, Kerstin Amann, Benno Weigmann, Helmut Neumann, Maximilian J. Waldner, Stephen M. Hedrick, Stefan Tenzer, Markus F. Neurath and Christoph Becker

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1 pp. 340-343

Jan E. Carette, Matthijs Raaben, Anthony C. Wong, Andrew S. Herbert, Gregor Obernosterer, Nirupama Mulherkar, Ana I. Kuehne, Philip J. Kranzusch, April M. Griffin, Gordon Ruthel, Paola Dal Cin, John M. Dye, Sean P. Whelan, Kartik Chandran and Thijn R. Brummelkamp

Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection pp. 344-348

Marceline Côté, John Misasi, Tao Ren, Anna Bruchez, Kyungae Lee, Claire Marie Filone, Lisa Hensley, Qi Li, Daniel Ory, Kartik Chandran and James Cunningham

A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1 pp. 349-353

Makoto R. Hara, Jeffrey J. Kovacs, Erin J. Whalen, Sudarshan Rajagopal, Ryan T. Strachan, Wayne Grant, Aaron J. Towers, Barbara Williams, Christopher M. Lam, Kunhong Xiao, Sudha K. Shenoy, Simon G. Gregory, Seungkirl Ahn, Derek R. Duckett and Robert J. Lefkowitz

In vitro centromere and kinetochore assembly on defined chromatin templates pp. 354-358

Annika Guse, Christopher W. Carroll, Ben Moree, Colin J. Fuller and Aaron F. Straight

Biomedical illustration: From monsters to molecules pp. 359-361

Corie Lok

Turning point: Jennifer Burney pp. 361-361

Virginia Gewin

Twitterspace pp. 364-364

William Meikle

2011, volume 477, articles 7363

Embrace failure to start up success pp. 133-133

Steve Blank

Fukushima impact is still hazy pp. 139-140

David Cyranoski and Geoff Brumfiel

NIH centre faces spell in limbo pp. 141-142

Meredith Wadman

Jumpy stars slow hunt for other Earths pp. 142-143

Ron Cowen

Venus scientists fear neglect pp. 145-145

Eric Hand

A radical approach to mental illness pp. 146-146

Alison Abbott

Climate and weather: Extreme measures pp. 148-149

Quirin Schiermeier

Biodefence since 9/11: The price of protection pp. 150-152

Erika Check Hayden

Homeland insecurity pp. 153-154

Peter D. Zimmerman

Crunch time for US science pp. 155-156

Jay Gulledge

Higher education: Academic questions pp. 158-159

David Helfand

Evolution: Small-town utopia pp. 160-160

Kevin Laland

Q&A: Mr Sustainability pp. 161-161

Nicola Jones

US private funder on indirect costs pp. 162-162

Susan M. Fitzpatrick

Improve China's sustainability targets pp. 162-162

Geng Yong

Flagging flora: help from bacteriocins? pp. 162-162

Paul D. Cotter, R. Paul Ross and Colin Hill

Flagging flora: heart disease link pp. 162-162

Sean Davidson

Broad escape from the abyss pp. 164-165

Alan P. Marscher

When lights take the circuits out pp. 165-166

João Peça and Guoping Feng

Let them eat fat pp. 166-167

Scott M. Sternson

Earth's patchy late veneer pp. 168-169

Thorsten Kleine

Let sleeping DNA lie pp. 169-170

Ashok R. Venkitaraman

Neocortical excitation/inhibition balance in information processing and social dysfunction pp. 171-178

Ofer Yizhar, Lief E. Fenno, Matthias Prigge, Franziska Schneider, Thomas J. Davidson, Daniel J. O’Shea, Vikaas S. Sohal, Inbal Goshen, Joel Finkelstein, Jeanne T. Paz, Katja Stehfest, Roman Fudim, Charu Ramakrishnan, John R. Huguenard, Peter Hegemann and Karl Deisseroth

BRCA1 tumour suppression occurs via heterochromatin-mediated silencing pp. 179-184

Quan Zhu, Gerald M. Pao, Alexis M. Huynh, Hoonkyo Suh, Nina Tonnu, Petra M. Nederlof, Fred H. Gage and Inder M. Verma

An origin of the radio jet in M87 at the location of the central black hole pp. 185-187

Kazuhiro Hada, Akihiro Doi, Motoki Kino, Hiroshi Nagai, Yoshiaki Hagiwara and Noriyuki Kawaguchi

Three classical Cepheid variable stars in the nuclear bulge of the Milky Way pp. 188-190

Noriyuki Matsunaga, Takahiro Kawadu, Shogo Nishiyama, Takahiro Nagayama, Naoto Kobayashi, Motohide Tamura, Giuseppe Bono, Michael W. Feast and Tetsuya Nagata

Magnetic-field-induced charge-stripe order in the high-temperature superconductor YBa2Cu3Oy pp. 191-194

Tao Wu, Hadrien Mayaffre, Steffen Krämer, Mladen Horvatić, Claude Berthier, W. N. Hardy, Ruixing Liang, D. A. Bonn and Marc-Henri Julien

The tungsten isotopic composition of the Earth’s mantle before the terminal bombardment pp. 195-198

Matthias Willbold, Tim Elliott and Stephen Moorbath

High plant diversity is needed to maintain ecosystem services pp. 199-202

Forest Isbell, Vincent Calcagno, Andy Hector, John Connolly, W. Stanley Harpole, Peter B. Reich, Michael Scherer-Lorenzen, Bernhard Schmid, David Tilman, Jasper van Ruijven, Alexandra Weigelt, Brian J. Wilsey, Erika S. Zavaleta and Michel Loreau

Chromosomal rearrangements maintain a polymorphic supergene controlling butterfly mimicry pp. 203-206

Mathieu Joron, Lise Frezal, Robert T. Jones, Nicola L. Chamberlain, Siu F. Lee, Christoph R. Haag, Annabel Whibley, Michel Becuwe, Simon W. Baxter, Laura Ferguson, Paul A. Wilkinson, Camilo Salazar, Claire Davidson, Richard Clark, Michael A. Quail, Helen Beasley, Rebecca Glithero, Christine Lloyd, Sarah Sims, Matthew C. Jones, Jane Rogers, Chris D. Jiggins and Richard H. ffrench-Constant

The genome sequence of Atlantic cod reveals a unique immune system pp. 207-210

Bastiaan Star, Alexander J. Nederbragt, Sissel Jentoft, Unni Grimholt, Martin Malmstrøm, Tone F. Gregers, Trine B. Rounge, Jonas Paulsen, Monica H. Solbakken, Animesh Sharma, Ola F. Wetten, Anders Lanzén, Roger Winer, James Knight, Jan-Hinnerk Vogel, Bronwen Aken, Øivind Andersen, Karin Lagesen, Ave Tooming-Klunderud, Rolf B. Edvardsen, Kirubakaran G. Tina, Mari Espelund, Chirag Nepal, Christopher Previti, Bård Ove Karlsen, Truls Moum, Morten Skage, Paul R. Berg, Tor Gjøen, Heiner Kuhl, Jim Thorsen, Ketil Malde, Richard Reinhardt, Lei Du, Steinar D. Johansen, Steve Searle, Sigbjørn Lien, Frank Nilsen, Inge Jonassen, Stig W. Omholt, Nils Chr. Stenseth and Kjetill S. Jakobsen

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia pp. 211-215

Han-Xiang Deng, Wenjie Chen, Seong-Tshool Hong, Kym M. Boycott, George H. Gorrie, Nailah Siddique, Yi Yang, Faisal Fecto, Yong Shi, Hong Zhai, Hujun Jiang, Makito Hirano, Evadnie Rampersaud, Gerard H. Jansen, Sandra Donkervoort, Eileen H. Bigio, Benjamin R. Brooks, Kaouther Ajroud, Robert L. Sufit, Jonathan L. Haines, Enrico Mugnaini, Margaret A. Pericak-Vance and Teepu Siddique

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells pp. 216-219

Thomas Gebhardt, Paul G. Whitney, Ali Zaid, Laura K. Mackay, Andrew G. Brooks, William R. Heath, Francis R. Carbone and Scott N. Mueller

Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein pp. 220-224

Daeho Park, Claudia Z. Han, Michael R. Elliott, Jason M. Kinchen, Paul C. Trampont, Soumita Das, Sheila Collins, Jeffrey J. Lysiak, Kyle L. Hoehn and Kodi S. Ravichandran

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase pp. 225-228

Christian Frezza, Liang Zheng, Ori Folger, Kartik N. Rajagopalan, Elaine D. MacKenzie, Livnat Jerby, Massimo Micaroni, Barbara Chaneton, Julie Adam, Ann Hedley, Gabriela Kalna, Ian P. M. Tomlinson, Patrick J. Pollard, Dave G. Watson, Ralph J. Deberardinis, Tomer Shlomi, Eytan Ruppin and Eyal Gottlieb

TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation pp. 229-233

Mark C. Siracusa, Steven A. Saenz, David A. Hill, Brian S. Kim, Mark B. Headley, Travis A. Doering, E. John Wherry, Heidi K. Jessup, Lori A. Siegel, Taku Kambayashi, Emily C. Dudek, Masato Kubo, Antonella Cianferoni, Jonathan M. Spergel, Steven F. Ziegler, Michael R. Comeau and David Artis

N2O binding at a [4Cu:2S] copper–sulphur cluster in nitrous oxide reductase pp. 234-237

Anja Pomowski, Walter G. Zumft, Peter M. H. Kroneck and Oliver Einsle

Erratum: Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells pp. 238-238

Lucia Ricci-Vitiani, Roberto Pallini, Mauro Biffoni, Matilde Todaro, Gloria Invernici, Tonia Cenci, Giulio Maira, Eugenio Agostino Parati, Giorgio Stassi, Luigi Maria Larocca and Ruggero De Maria

Erratum: DMRT1 prevents female reprogramming in the postnatal mammalian testis pp. 238-238

Clinton K. Matson, Mark W. Murphy, Aaron L. Sarver, Michael D. Griswold, Vivian J. Bardwell and David Zarkower

Academia: Small-school science pp. 239-241

Karen Kaplan

Turning point: Sarah Schaack pp. 241-241

Virginia Gewin

NPG's policy on authorship pp. 244-244

Jordan Suchow

2011, volume 477, articles 7362

Between Elmo and Einstein pp. 1-1

Lydia Murray

The Arab Spring offers hope but no quick fix pp. 7-7

Rana Dajani

Japan's new leader faces energy gap pp. 13-14

David Cyranoski

Halfway point for 1,001 genomes quest pp. 14-14

Heidi Ledford

Twins to probe Moon's heart pp. 16-17

Eric Hand

Scientists promised 'one voice' in European policy pp. 18-18

Natasha Gilbert

Work ethic: The 24/7 lab pp. 20-22

Heidi Ledford

Neuroscience vs philosophy: Taking aim at free will pp. 23-25

Kerri Smith

A healthy work–life balance can enhance research pp. 27-28

Julie Overbaugh

Ecology: Redefining nature pp. 29-30

Shahid Naeem

Particle physics: Inside the collider pp. 30-31

Joseph Silk

Q&A: Comic creator pp. 32-32

Marc Weidenbaum

Loophole in forest plan for Indonesia pp. 33-33

David P. Edwards and William F. Laurance

Call to save science institute in Turkey pp. 33-33

Ayşe Erzan and Cihan Saçlıoğlu

Drug firm monitors waste water pp. 33-33

Jason Snape, Chris Lewis and Richard Murray-Smith

Diploma database to encourage mobility pp. 33-33

Ana M. C. Santos

Baruj Benacerraf (1920–2011) pp. 34-34

Ronald N. Germain and William E. Paul

How to escape treatment pp. 36-37

Steven G. Deeks

A hint of normality at last? pp. 37-39

John E. Norris

Nitrogen from the deep pp. 39-40

Edward A. G. Schuur

Tumour-fighting virus homes in pp. 40-41

Evanthia Galanis

Blood ties pp. 41-42

Richard M. Ransohoff

Dry solution to a sticky problem pp. 42-43

Jeffrey M. Karp and Robert Langer

Synthesis, assembly and applications of semiconductor nanomembranes pp. 45-53

J. A. Rogers, M. G. Lagally and R. G. Nuzzo

Human metabolic individuality in biomedical and pharmaceutical research pp. 54-60

Karsten Suhre, So-Youn Shin, Ann-Kristin Petersen, Robert P. Mohney, David Meredith, Brigitte Wägele, Elisabeth Altmaier, Panos Deloukas, Jeanette Erdmann, Elin Grundberg, Christopher J. Hammond, Martin Hrabé de Angelis, Gabi Kastenmüller, Anna Köttgen, Florian Kronenberg, Massimo Mangino, Christa Meisinger, Thomas Meitinger, Hans-Werner Mewes, Michael V. Milburn, Cornelia Prehn, Johannes Raffler, Janina S. Ried, Werner Römisch-Margl, Nilesh J. Samani, Kerrin S. Small, H. -Erich Wichmann, Guangju Zhai, Thomas Illig, Tim D. Spector, Jerzy Adamski, Nicole Soranzo and Christian Gieger

The mechanism of membrane-associated steps in tail-anchored protein insertion pp. 61-66

Malaiyalam Mariappan, Agnieszka Mateja, Malgorzata Dobosz, Elia Bove, Ramanujan S. Hegde and Robert J. Keenan

An extremely primitive star in the Galactic halo pp. 67-69

Elisabetta Caffau, Piercarlo Bonifacio, Patrick François, Luca Sbordone, Lorenzo Monaco, Monique Spite, François Spite, Hans-G. Ludwig, Roger Cayrel, Simone Zaggia, François Hammer, Sofia Randich, Paolo Molaro and Vanessa Hill

Chronological evidence that the Moon is either young or did not have a global magma ocean pp. 70-72

Lars E. Borg, James N. Connelly, Maud Boyet and Richard W. Carlson

Real-time quantum feedback prepares and stabilizes photon number states pp. 73-77

Clément Sayrin, Igor Dotsenko, Xingxing Zhou, Bruno Peaudecerf, Théo Rybarczyk, Sébastien Gleyzes, Pierre Rouchon, Mazyar Mirrahimi, Hadis Amini, Michel Brune, Jean-Michel Raimond and Serge Haroche

Increased forest ecosystem carbon and nitrogen storage from nitrogen rich bedrock pp. 78-81

Scott L. Morford, Benjamin Z. Houlton and Randy A. Dahlgren

An earlier origin for the Acheulian pp. 82-85

Christopher J. Lepre, Hélène Roche, Dennis V. Kent, Sonia Harmand, Rhonda L. Quinn, Jean-Philippe Brugal, Pierre-Jean Texier, Arnaud Lenoble and Craig S. Feibel

Transient dynamics of an altered large marine ecosystem pp. 86-89

Kenneth T. Frank, Brian Petrie, Jonathan A. D. Fisher and William C. Leggett

The ageing systemic milieu negatively regulates neurogenesis and cognitive function pp. 90-94

Saul A. Villeda, Jian Luo, Kira I. Mosher, Bende Zou, Markus Britschgi, Gregor Bieri, Trisha M. Stan, Nina Fainberg, Zhaoqing Ding, Alexander Eggel, Kurt M. Lucin, Eva Czirr, Jeong-Soo Park, Sebastien Couillard-Després, Ludwig Aigner, Ge Li, Elaine R. Peskind, Jeffrey A. Kaye, Joseph F. Quinn, Douglas R. Galasko, Xinmin S. Xie, Thomas A. Rando and Tony Wyss-Coray

Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy pp. 95-98

Alex Sigal, Jocelyn T. Kim, Alejandro B. Balazs, Erez Dekel, Avi Mayo, Ron Milo and David Baltimore

Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans pp. 99-102

Caroline J. Breitbach, James Burke, Derek Jonker, Joe Stephenson, Andrew R. Haas, Laura Q. M. Chow, Jorge Nieva, Tae-Ho Hwang, Anne Moon, Richard Patt, Adina Pelusio, Fabrice Le Boeuf, Joe Burns, Laura Evgin, Naomi De Silva, Sara Cvancic, Terri Robertson, Ji-Eun Je, Yeon-Sook Lee, Kelley Parato, Jean-Simon Diallo, Aaron Fenster, Manijeh Daneshmand, John C. Bell and David H. Kirn

Modulation of Rab GTPase function by a protein phosphocholine transferase pp. 103-106

Shaeri Mukherjee, Xiaoyun Liu, Kohei Arasaki, Justin McDonough, Jorge E. Galán and Craig R. Roy

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation pp. 107-110

Tim Bartels, Joanna G. Choi and Dennis J. Selkoe

Solution structure of a minor and transiently formed state of a T4 lysozyme mutant pp. 111-114

Guillaume Bouvignies, Pramodh Vallurupalli, D. Flemming Hansen, Bruno E. Correia, Oliver Lange, Alaji Bah, Robert M. Vernon, Frederick W. Dahlquist, David Baker and Lewis E. Kay

Protection of repetitive DNA borders from self-induced meiotic instability pp. 115-119

Gerben Vader, Hannah G. Blitzblau, Mihoko A. Tame, Jill E. Falk, Lisa Curtin and Andreas Hochwagen

Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor pp. 120-120

Kerry J. Ressler, Kristina B. Mercer, Bekh Bradley, Tanja Jovanovic, Amy Mahan, Kimberly Kerley, Seth D. Norrholm, Varun Kilaru, Alicia K. Smith, Amanda J. Myers, Manuel Ramirez, Anzhelika Engel, Sayamwong E. Hammack, Donna Toufexis, Karen M. Braas, Elisabeth B. Binder and Victor May

Florida: Second thoughts pp. 121-122

Sarah Kellogg

The magical world of data sharing pp. 123-123

Andrew Peterman

A sentence to life pp. 126-126

Igor Teper