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2017, volume 548, articles 7669

Keep on marching for science education pp. 501-501

Brandon Haught

Europe’s X-ray laser fires up pp. 507-508

Philip Ball

Legal threat exposes gaps in climate-change planning pp. 508-509

Nicky Phillips

US science envoy resigns in protest at Trump policies pp. 509-509

Jeff Tollefson

Dinosaur trio roosted together like birds pp. 510-510

Traci Watson

Scientists solve mystery of US Civil War submarine pp. 511-511

Ben Upton

Cassini’s 13 years of stunning Saturn science — in pictures pp. 512-516

Alexandra Witze

Stop blocking postdocs’ paths to success pp. 517-519

Ben A. Barres

Artificial intelligence: The future is superintelligent pp. 520-521

Stuart Russell

Books in brief pp. 521-521

Barbara Kiser

Economics: Messy genesis of the welfare state pp. 522-522

Paul Cairney

US coal plans flout mercury convention pp. 523-523

Oladele A. Ogunseitan

Philanthropy research is thriving pp. 523-523

Amir Pasic

Enlist blockchain to boost conservation pp. 523-523

Zachary Baynham-Herd

Open data settled in materials theory pp. 523-523

Claudia Draxl, Francesc Illas and Matthias Scheffler

Most lobotomies were done on women pp. 523-523

Louis-Marie Terrier, Marc Levêque and Aymeric Amelot

Cosmic exhumation pp. 526-527

Steven N. Shore

The case of the mysterious messenger pp. 527-528

Kaitlin Johnson and Scott Bailey

Food for early animal evolution pp. 528-530

Andrew H. Knoll

Putative medicines that mimic mutations pp. 530-531

Sekar Kathiresan

Volcanism caused ancient global warming pp. 531-533

Katrin J. Meissner and Timothy J. Bralower

A toxin that fuels metabolism pp. 533-534

Xiaojing Liu and Jason W. Locasale

The inflammasome turns 15 pp. 534-535

Mohamed Lamkanfi and Vishva M. Dixit

Identification of essential genes for cancer immunotherapy pp. 537-542

Shashank J. Patel, Neville E. Sanjana, Rigel J. Kishton, Arash Eidizadeh, Suman K. Vodnala, Maggie Cam, Jared J. Gartner, Li Jia, Seth M. Steinberg, Tori N. Yamamoto, Anand S. Merchant, Gautam U. Mehta, Anna Chichura, Ophir Shalem, Eric Tran, Robert Eil, Madhusudhanan Sukumar, Eva Perez Guijarro, Chi-Ping Day, Paul Robbins, Steve Feldman, Glenn Merlino, Feng Zhang and Nicholas P. Restifo

Type III CRISPR–Cas systems produce cyclic oligoadenylate second messengers pp. 543-548

Ole Niewoehner, Carmela Garcia-Doval, Jakob T. Rostøl, Christian Berk, Frank Schwede, Laurent Bigler, Jonathan Hall, Luciano A. Marraffini and Martin Jinek

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism pp. 549-554

Guillermo Burgos-Barragan, Niek Wit, Johannes Meiser, Felix A. Dingler, Matthias Pietzke, Lee Mulderrig, Lucas B. Pontel, Ivan V. Rosado, Thomas F. Brewer, Rebecca L. Cordell, Paul S. Monks, Christopher J. Chang, Alexei Vazquez and Ketan J. Patel

Fast automated analysis of strong gravitational lenses with convolutional neural networks pp. 555-557

Yashar D. Hezaveh, Laurence Perreault Levasseur and Philip J. Marshall

Proper-motion age dating of the progeny of Nova Scorpii AD 1437 pp. 558-560

M. M. Shara, K. Iłkiewicz, J. Mikołajewska, A. Pagnotta, M. F. Bode, L. A. Crause, K. Drozd, J. Faherty, I. Fuentes-Morales, J. E. Grindlay, A. F. J. Moffat, M. L. Pretorius, L. Schmidtobreick, F. R. Stephenson, C. Tappert and D. Zurek

Magnetic antiskyrmions above room temperature in tetragonal Heusler materials pp. 561-566

Ajaya K. Nayak, Vivek Kumar, Tianping Ma, Peter Werner, Eckhard Pippel, Roshnee Sahoo, Franoise Damay, Ulrich K. Rößler, Claudia Felser and Stuart S. P. Parkin

Molecular machines open cell membranes pp. 567-572

Víctor García-López, Fang Chen, Lizanne G. Nilewski, Guillaume Duret, Amir Aliyan, Anatoly B. Kolomeisky, Jacob T. Robinson, Gufeng Wang, Robert Pal and James M. Tour

Very large release of mostly volcanic carbon during the Palaeocene–Eocene Thermal Maximum pp. 573-577

Marcus Gutjahr, Andy Ridgwell, Philip F. Sexton, Eleni Anagnostou, Paul N. Pearson, Heiko Pälike, Richard D. Norris, Ellen Thomas and Gavin L. Foster

The rise of algae in Cryogenian oceans and the emergence of animals pp. 578-581

Jochen J. Brocks, Amber J. M. Jarrett, Eva Sirantoine, Christian Hallmann, Yosuke Hoshino and Tharika Liyanage

Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep pp. 582-587

Kai Liu, Juhyun Kim, Dong Won Kim, Yi Stephanie Zhang, Hechen Bao, Myrto Denaxa, Szu-Aun Lim, Eileen Kim, Chang Liu, Ian R. Wickersham, Vassilis Pachnis, Samer Hattar, Juan Song, Solange P. Brown and Seth Blackshaw

Feedback regulation of steady-state epithelial turnover and organ size pp. 588-591

Jackson Liang, Shruthi Balachandra, Sang Ngo and Lucy Erin O’Brien

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model pp. 592-596

Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Hiroaki Magotani, Hirotaka Onoe, Takuya Hayashi, Hiroshi Mizuma, Sayuki Takara, Ryosuke Takahashi, Haruhisa Inoue, Satoshi Morita, Michio Yamamoto, Keisuke Okita, Masato Nakagawa, Malin Parmar and Jun Takahashi

Public antibodies to malaria antigens generated by two LAIR1 insertion modalities pp. 597-601

Kathrin Pieper, Joshua Tan, Luca Piccoli, Mathilde Foglierini, Sonia Barbieri, Yiwei Chen, Chiara Silacci-Fregni, Tobias Wolf, David Jarrossay, Marica Anderle, Abdirahman Abdi, Francis M. Ndungu, Ogobara K. Doumbo, Boubacar Traore, Tuan M. Tran, Said Jongo, Isabelle Zenklusen, Peter D. Crompton, Claudia Daubenberger, Peter C. Bull, Federica Sallusto and Antonio Lanzavecchia

Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling pp. 602-606

Kai Yang, Daniel Bastardo Blanco, Geoffrey Neale, Peter Vogel, Julian Avila, Clary B. Clish, Chuan Wu, Sharad Shrestha, Sherri Rankin, Lingyun Long, Anil Kc and Hongbo Chi

ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference pp. 607-611

Geoffrey P. Dann, Glen P. Liszczak, John D. Bagert, Manuel M. Müller, Uyen T. T. Nguyen, Felix Wojcik, Zachary Z. Brown, Jeffrey Bos, Tatyana Panchenko, Rasmus Pihl, Samuel B. Pollock, Katharine L. Diehl, C. David Allis and Tom W. Muir

Correction: Corrigendum: Complex pectin metabolism by gut bacteria reveals novel catalytic functions pp. 612-612

Didier Ndeh, Artur Rogowski, Alan Cartmell, Ana S. Luis, Arnaud Baslé, Joseph Gray, Immacolata Venditto, Jonathon Briggs, Xiaoyang Zhang, Aurore Labourel, Nicolas Terrapon, Fanny Buffetto, Sergey Nepogodiev, Yao Xiao, Robert A. Field, Yanping Zhu, Malcolm A. O’Neill, Breeanna R. Urbanowicz, William S. York, Gideon J. Davies, D. Wade Abbott, Marie-Christine Ralet, Eric C. Martens, Bernard Henrissat and Harry J. Gilbert

Erratum: Host and viral traits predict zoonotic spillover from mammals pp. 612-612

Kevin J. Olival, Parviez R. Hosseini, Carlos Zambrana-Torrelio, Noam Ross, Tiffany L. Bogich and Peter Daszak

Erratum: Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism pp. 612-612

Guillermo Burgos-Barragan, Niek Wit, Johannes Meiser, Felix A. Dingler, Matthias Pietzke, Lee Mulderrig, Lucas B. Pontel, Ivan V. Rosado, Thomas F. Brewer, Rebecca L. Cordell, Paul S. Monks, Christopher J. Chang, Alexei Vazquez and Ketan J. Patel

Information management: Data domination pp. 613-614

Gaia Donati and Chris Woolston

Turning point: Refugee role model pp. 615-615

Virginia Gewin

Geode pp. 618-618

John Gilbey

2017, volume 548, articles 7668

Critical limb ischaemia: artery repair pp. S41-S41

David Holmes

Saving life and limb pp. S42-S43

David Holmes

To reduce gender biases, acknowledge them pp. 373-373

Debbie Chachra

How machine learning could help to improve climate forecasts pp. 379-379

Nicola Jones

Supernova’s messy birth casts doubt on reliability of astronomical yardstick pp. 379-380

Shannon Hall

Ecologists protest Australia’s plans to cut funding for environment-monitoring network pp. 381-382

Nicky Phillips

Mysteries of turbulence unravelled pp. 382-383

Davide Castelvecchi

Theft of South African relics riles researchers pp. 383-383

Sarah Wild

Creeping earth could hold secret to deadly landslides pp. 384-386

Jane Palmer

A long journey to reproducible results pp. 387-388

Gordon J. Lithgow, Monica Driscoll and Patrick Phillips

Evolution: Darwin's domestic discoveries pp. 389-390

Henry Nicholls

Conservation: The great US land grab pp. 390-391

Kierán Suckling

Space science: Voyager at 40 pp. 392-392

Alexandra Witze

Could fracking creep under the radar? pp. 393-393

David Smythe and Stuart Haszeldine

Fake serum has telltale fingerprint pp. 393-393

Robert Curry

Rename the impact factor pp. 393-393

Ajit Varki

Signing up to safe water for billions pp. 393-393

R. Quentin Grafton, Asit K. Biswas and Cecilia Tortajada

Patrick Bateson (1938–2017) pp. 394-394

Kevin N. Laland

Diversity reaches the stars pp. 396-397

Laura E. Clarke and Shane A. Liddelow

History of black holes revealed by their spin pp. 397-398

Steinn Sigurðsson

At the heart of gene edits in human embryos pp. 398-400

Nerges Winblad and Fredrik Lanner

Magnetic molecules back in the race pp. 400-401

Roberta Sessoli

Role of mutation in fly-wing evolution pp. 401-403

James Cheverud

Ancient ice and the global methane cycle pp. 403-404

Peter Hopcroft

Probiotic prevents infections in newborns pp. 404-405

Daniel J. Tancredi

A randomized synbiotic trial to prevent sepsis among infants in rural India pp. 407-412

Pinaki Panigrahi, Sailajanandan Parida, Nimai C. Nanda, Radhanath Satpathy, Lingaraj Pradhan, Dinesh S. Chandel, Lorena Baccaglini, Arjit Mohapatra, Subhranshu S. Mohapatra, Pravas R. Misra, Rama Chaudhry, Hegang H. Chen, Judith A. Johnson, J. Glenn Morris, Nigel Paneth and Ira H. Gewolb

Correction of a pathogenic gene mutation in human embryos pp. 413-419

Hong Ma, Nuria Marti-Gutierrez, Sang-Wook Park, Jun Wu, Yeonmi Lee, Keiichiro Suzuki, Amy Koski, Dongmei Ji, Tomonari Hayama, Riffat Ahmed, Hayley Darby, Crystal Van Dyken, Ying Li, Eunju Kang, A.-Reum Park, Daesik Kim, Sang-Tae Kim, Jianhui Gong, Ying Gu, Xun Xu, David Battaglia, Sacha A. Krieg, David M. Lee, Diana H. Wu, Don P. Wolf, Stephen B. Heitner, Juan Carlos Izpisua Belmonte, Paula Amato, Jin-Soo Kim, Sanjiv Kaul and Shoukhrat Mitalipov

The primed SNARE–complexin–synaptotagmin complex for neuronal exocytosis pp. 420-425

Qiangjun Zhou, Peng Zhou, Austin L. Wang, Dick Wu, Minglei Zhao, Thomas C. Südhof and Axel T. Brunger

Distinguishing spin-aligned and isotropic black hole populations with gravitational waves pp. 426-429

Will M. Farr, Simon Stevenson, M. Coleman Miller, Ilya Mandel, Ben Farr and Alberto Vecchio

Large turbulent reservoirs of cold molecular gas around high-redshift starburst galaxies pp. 430-433

E. Falgarone, M. A. Zwaan, B. Godard, E. Bergin, R. J. Ivison, P. M. Andreani, F. Bournaud, R. S. Bussmann, D. Elbaz, A. Omont, I. Oteo and F. Walter

RETRACTED ARTICLE: Epitaxy of advanced nanowire quantum devices pp. 434-438

Sasa Gazibegovic, Diana Car, Hao Zhang, Stijn C. Balk, John A. Logan, Michiel W. A. de Moor, Maja C. Cassidy, Rudi Schmits, Di Xu, Guanzhong Wang, Peter Krogstrup, Roy L. M. Op het Veld, Kun Zuo, Yoram Vos, Jie Shen, Daniël Bouman, Borzoyeh Shojaei, Daniel Pennachio, Joon Sue Lee, Petrus J. van Veldhoven, Sebastian Koelling, Marcel A. Verheijen, Leo P. Kouwenhoven, Chris J. Palmstrøm and Erik P. A. M. Bakkers

Molecular magnetic hysteresis at 60 kelvin in dysprosocenium pp. 439-442

Conrad A. P. Goodwin, Fabrizio Ortu, Daniel Reta, Nicholas F. Chilton and David P. Mills

Minimal geological methane emissions during the Younger Dryas–Preboreal abrupt warming event pp. 443-446

Vasilii V. Petrenko, Andrew M. Smith, Hinrich Schaefer, Katja Riedel, Edward Brook, Daniel Baggenstos, Christina Harth, Quan Hua, Christo Buizert, Adrian Schilt, Xavier Fain, Logan Mitchell, Thomas Bauska, Anais Orsi, Ray F. Weiss and Jeffrey P. Severinghaus

Mutation predicts 40 million years of fly wing evolution pp. 447-450

David Houle, Geir H. Bolstad, Kim van der Linde and Thomas F. Hansen

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis pp. 451-455

Michael Sigal, Catriona Y. Logan, Marta Kapalczynska, Hans-Joachim Mollenkopf, Hilmar Berger, Bertram Wiedenmann, Roeland Nusse, Manuel R. Amieva and Thomas F. Meyer

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo pp. 456-460

Weike Pei, Thorsten B. Feyerabend, Jens Rössler, Xi Wang, Daniel Postrach, Katrin Busch, Immanuel Rode, Kay Klapproth, Nikolaus Dietlein, Claudia Quedenau, Wei Chen, Sascha Sauer, Stephan Wolf, Thomas Höfer and Hans-Reimer Rodewald

cGAS surveillance of micronuclei links genome instability to innate immunity pp. 461-465

Karen J. Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J. Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K. Rainger, Andrea Leitch, Ruby T. Osborn, Ann P. Wheeler, Marcin Nowotny, Nick Gilbert, Tamir Chandra, Martin A. M. Reijns and Andrew P. Jackson

Mitotic progression following DNA damage enables pattern recognition within micronuclei pp. 466-470

Shane M. Harding, Joseph L. Benci, Jerome Irianto, Dennis E. Discher, Andy J. Minn and Roger A. Greenberg

CDK4/6 inhibition triggers anti-tumour immunity pp. 471-475

Shom Goel, Molly J. DeCristo, April C. Watt, Haley BrinJones, Jaclyn Sceneay, Ben B. Li, Naveed Khan, Jessalyn M. Ubellacker, Shaozhen Xie, Otto Metzger-Filho, Jeremy Hoog, Matthew J. Ellis, Cynthia X. Ma, Susanne Ramm, Ian E. Krop, Eric P. Winer, Thomas M. Roberts, Hye-Jung Kim, Sandra S. McAllister and Jean J. Zhao

Vaccine-driven pharmacodynamic dissection and mitigation of fenethylline psychoactivity pp. 476-479

Cody J. Wenthur, Bin Zhou and Kim D. Janda

Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure pp. 480-484

Xiangyu Liu, Seungkirl Ahn, Alem W. Kahsai, Kai-Cheng Meng, Naomi R. Latorraca, Biswaranjan Pani, A. J. Venkatakrishnan, Ali Masoudi, William I. Weis, Ron O. Dror, Xin Chen, Robert J. Lefkowitz and Brian K. Kobilka

Check your chemistry pp. 485-488

Monya Baker

Career development: A plan for action pp. 489-490

Julie Gould

It's good to have lots of bad ideas pp. 491-491

John Kirwan

Excerpts from the 100-day food diary of Angela Meyer pp. 494-494

Beth Cato

2017, volume 548, articles 7667

A little democracy could go a long way pp. 261-261

Ehsan Masood

California scientists push to create massive climate-research programme pp. 267-268

Jeff Tollefson

China launches brain-imaging factory pp. 268-269

David Cyranoski

Massive El Niño sent greenhouse-gas emissions soaring pp. 269-269

Gabriel Popkin

Thousands across India march in support of science pp. 270-270

T. V. Padma

US biomedical-research facilities unprepared for attacks and natural disasters pp. 270-270

Sara Reardon

Why 14 ecology labs teamed up to watch grass grow pp. 271-271

Ewen Callaway

China’s embrace of embryo selection raises thorny questions pp. 272-274

David Cyranoski

Revitalize the world’s countryside pp. 275-277

Yansui Liu and Yuheng Li

Seismology: Quake news from America pp. 278-279

Roger Bilham

Books in brief pp. 279-279

Barbara Kiser

Data sharing: guard the privacy of donors pp. 281-281

Shirley Y. Hill

Data sharing: do scientists know best? pp. 281-281

David Lambert, Craig Millar and Eske Willerslev

Past US floods give lessons in retreat pp. 281-281

A. R. Siders

More nuclear power can speed CO2 cuts pp. 281-281

Richard Rhodes

Ingenious solutions sparked by a crisis pp. 281-281

Biswa Prasun Chatterji

Origins of Atlantic decadal swings pp. 284-285

Gabriel A. Vecchi, Thomas L. Delworth and Ben Booth

A bitter–sweet symphony pp. 285-287

Jiefu Li and Liqun Luo

Human metastases under scrutiny pp. 287-288

G. Steven Bova

A turbulent stellar atmosphere in full view pp. 288-289

Gail H. Schaefer

Healthy skin rejects cancer pp. 289-290

Joseph Burclaff and Jason C. Mills

New gliding mammaliaforms from the Jurassic pp. 291-296

Qing-Jin Meng, David M. Grossnickle, Di Liu, Yu-Guang Zhang, April I. Neander, Qiang Ji and Zhe-Xi Luo

Integrative clinical genomics of metastatic cancer pp. 297-303

Dan R. Robinson, Yi-Mi Wu, Robert J. Lonigro, Pankaj Vats, Erin Cobain, Jessica Everett, Xuhong Cao, Erica Rabban, Chandan Kumar-Sinha, Victoria Raymond, Scott Schuetze, Ajjai Alva, Javed Siddiqui, Rashmi Chugh, Francis Worden, Mark M. Zalupski, Jeffrey Innis, Rajen J. Mody, Scott A. Tomlins, David Lucas, Laurence H. Baker, Nithya Ramnath, Ann F. Schott, Daniel F. Hayes, Joseph Vijai, Kenneth Offit, Elena M. Stoffel, J. Scott Roberts, David C. Smith, Lakshmi P. Kunju, Moshe Talpaz, Marcin Cieślik and Arul M. Chinnaiyan

Ram-pressure feeding of supermassive black holes pp. 304-309

Bianca M. Poggianti, Yara L. Jaffé, Alessia Moretti, Marco Gullieuszik, Mario Radovich, Stephanie Tonnesen, Jacopo Fritz, Daniela Bettoni, Benedetta Vulcani, Giovanni Fasano, Callum Bellhouse, George Hau and Alessandro Omizzolo

Vigorous atmospheric motion in the red supergiant star Antares pp. 310-312

K. Ohnaka, G. Weigelt and K.-H. Hofmann

Electronic in-plane symmetry breaking at field-tuned quantum criticality in CeRhIn5 pp. 313-317

F. Ronning, T. Helm, K. R. Shirer, M. D. Bachmann, L. Balicas, M. K. Chan, B. J. Ramshaw, R. D. McDonald, F. F. Balakirev, M. Jaime, E. D. Bauer and P. J. W. Moll

Chaotic dynamics in nanoscale NbO2 Mott memristors for analogue computing pp. 318-321

Suhas Kumar, John Paul Strachan and R. Stanley Williams

An early modern human presence in Sumatra 73,000–63,000 years ago pp. 322-325

K. E. Westaway, J. Louys, R. Due Awe, M. J. Morwood, G. J. Price, J.-x. Zhao, M. Aubert, R. Joannes-Boyau, T. M. Smith, M. M. Skinner, T. Compton, R. M. Bailey, G. D. van den Bergh, J. de Vos, A. W. G. Pike, C. Stringer, E. W. Saptomo, Y. Rizal, J. Zaim, W. D. Santoso, A. Trihascaryo, L. Kinsley and B. Sulistyanto

New evidence for mammaliaform ear evolution and feeding adaptation in a Jurassic ecosystem pp. 326-329

Zhe-Xi Luo, Qing-Jin Meng, David M. Grossnickle, Di Liu, April I. Neander, Yu-Guang Zhang and Qiang Ji

Rewiring the taste system pp. 330-333

Hojoon Lee, Lindsey J. Macpherson, Camilo A. Parada, Charles S. Zuker and Nicholas J. P. Ryba

Correction of aberrant growth preserves tissue homeostasis pp. 334-337

Samara Brown, Cristiana M. Pineda, Tianchi Xin, Jonathan Boucher, Kathleen C. Suozzi, Sangbum Park, Catherine Matte-Martone, David G. Gonzalez, Julie Rytlewski, Slobodan Beronja and Valentina Greco

m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways pp. 338-342

Hua-Bing Li, Jiyu Tong, Shu Zhu, Pedro J. Batista, Erin E. Duffy, Jun Zhao, Will Bailis, Guangchao Cao, Lina Kroehling, Yuanyuan Chen, Geng Wang, James P. Broughton, Y. Grace Chen, Yuval Kluger, Matthew D. Simon, Howard Y. Chang, Zhinan Yin and Richard A. Flavell

Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood pp. 343-346

Julia Joung, Jesse M. Engreitz, Silvana Konermann, Omar O. Abudayyeh, Vanessa K. Verdine, Francois Aguet, Jonathan S. Gootenberg, Neville E. Sanjana, Jason B. Wright, Charles P. Fulco, Yuen-Yi Tseng, Charles H. Yoon, Jesse S. Boehm, Eric S. Lander and Feng Zhang

mRNA 3′ uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome pp. 347-351

Marcos Morgan, Christian Much, Monica DiGiacomo, Chiara Azzi, Ivayla Ivanova, Dimitrios M. Vitsios, Jelena Pistolic, Paul Collier, Pedro N. Moreira, Vladimir Benes, Anton J. Enright and Dónal O’Carroll

Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3 pp. 352-355

Stefan Schoebel, Wei Mi, Alexander Stein, Sergey Ovchinnikov, Ryan Pavlovicz, Frank DiMaio, David Baker, Melissa G. Chambers, Huayou Su, Dongsheng Li, Tom A. Rapoport and Maofu Liao

Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6 pp. 356-360

Reiya Taniguchi, Asuka Inoue, Misa Sayama, Akiharu Uwamizu, Keitaro Yamashita, Kunio Hirata, Masahito Yoshida, Yoshiki Tanaka, Hideaki E. Kato, Yoshiko Nakada-Nakura, Yuko Otani, Tomohiro Nishizawa, Takayuki Doi, Tomohiko Ohwada, Ryuichiro Ishitani, Junken Aoki and Osamu Nureki

Student immigration: The gamble of going abroad pp. 361-363

Virginia Gewin

Trade talk: Crime buster pp. 363-363

Julie Gould

First date with the Hive pp. 366-366

Gretchen Tessmer

2017, volume 548, articles 7666

Connecting big ideas to benefit pp. S3-S3

Nicky Phillips

Comment: Turning science into social outcomes pp. S8-S8

Richard Jefferson

Game-changers pp. S9-S11

Branwen Morgan and Annabel McGilvray

Role of stem-cell divisions in cancer risk pp. E13-E14

Cristian Tomasetti, Rick Durrett, Marek Kimmel, Amaury Lambert, Giovanni Parmigiani, Ann Zauber and Bert Vogelstein

Wu et al. reply pp. E15-E15

Song Wu, Wei Zhu and Yusuf A. Hannun

Profile: Michael Sporn: A legacy of greater knowledge pp. S16-S18

Elie Dolgin

Comment: Measure for measure pp. S22-S22

Aidan Byrne

On the right track pp. S23-S25

Neil Savage

Trials and tribulations pp. S28-S31

Sujata Gupta

Commit to talks on patient data and public health pp. 137-137

Vivienne Parry

Cosmic map reveals a not-so-lumpy Universe pp. 143-144

Davide Castelvecchi

Home-grown scientists step up to save Africa’s primates pp. 144-145

Declan Butler

Insomnia linked to premature birth in study of 3 million mothers pp. 145-145

Amy Maxmen

Mysteries of Sun’s corona on view during upcoming eclipse pp. 146-147

Alexandra Witze

Citizen scientists chase total solar eclipse pp. 147-147

Rachael Lallensack

First genetically engineered salmon sold in Canada pp. 148-148

Emily Waltz

Shake up conferences pp. 153-154

Shai D. Silberberg, Devon C. Crawford, Robert Finkelstein, Walter J. Koroshetz, Robert D. Blank, Hudson H. Freeze, Howard H. Garrison and Yvette R. Seger

Evolution: Parallel lives pp. 156-157

Kevin Padian

Books in brief pp. 157-157

Barbara Kiser

Ensure equal access to ancient DNA pp. 158-158

Cheryl Makarewicz, Nimrod Marom and Guy Bar-Oz

Crypto-control your own energy supply pp. 158-158

Merlinda Andoni, Valentin Robu and David Flynn

Next decade's goals for rare diseases pp. 158-158

Christopher P. Austin and Hugh J. S. Dawkins

Taxonomy: stable taxon boundaries pp. 158-158

Norbert Holstein and Federico Luebert

Skull secrets of an ancient ape pp. 160-161

Brenda R. Benefit

Optical sensing gets exceptional pp. 161-162

Mikael C. Rechtsman

Click and discover pp. 162-164

George S. Vassiliou and Shankar Balasubramanian

Trends in ecosystem recovery from drought pp. 164-165

Sonia I. Seneviratne and Philippe Ciais

The cost of perpetual youth pp. 165-166

Thomas P. Zwaka

Contests between species aid biodiversity pp. 166-167

James P. O'Dwyer

New infant cranium from the African Miocene sheds light on ape evolution pp. 169-174

Isaiah Nengo, Paul Tafforeau, Christopher C. Gilbert, John G. Fleagle, Ellen R. Miller, Craig Feibel, David L. Fox, Josh Feinberg, Kelsey D. Pugh, Camille Berruyer, Sara Mana, Zachary Engle and Fred Spoor

The complete connectome of a learning and memory centre in an insect brain pp. 175-182

Katharina Eichler, Feng Li, Ashok Litwin-Kumar, Youngser Park, Ingrid Andrade, Casey M. Schneider-Mizell, Timo Saumweber, Annina Huser, Claire Eschbach, Bertram Gerber, Richard D. Fetter, James W. Truman, Carey E. Priebe, L. F. Abbott, Andreas S. Thum, Marta Zlatic and Albert Cardona

No large population of unbound or wide-orbit Jupiter-mass planets pp. 183-186

Przemek Mróz, Andrzej Udalski, Jan Skowron, Radosław Poleski, Szymon Kozłowski, Michał K. Szymański, Igor Soszyński, Łukasz Wyrzykowski, Paweł Pietrukowicz, Krzysztof Ulaczyk, Dorota Skowron and Michał Pawlak

Enhanced sensitivity at higher-order exceptional points pp. 187-191

Hossein Hodaei, Absar U. Hassan, Steffen Wittek, Hipolito Garcia-Gracia, Ramy El-Ganainy, Demetrios N. Christodoulides and Mercedeh Khajavikhan

Exceptional points enhance sensing in an optical microcavity pp. 192-196

Weijian Chen, Şahin Kaya Özdemir, Guangming Zhao, Jan Wiersig and Lan Yang

High-temperature crystallization of nanocrystals into three-dimensional superlattices pp. 197-201

Liheng Wu, Joshua J. Willis, Ian Salmon McKay, Benjamin T. Diroll, Jian Qin, Matteo Cargnello and Christopher J. Tassone

Global patterns of drought recovery pp. 202-205

Christopher R. Schwalm, William R. L. Anderegg, Anna M. Michalak, Joshua B. Fisher, Franco Biondi, George Koch, Marcy Litvak, Kiona Ogle, John D. Shaw, Adam Wolf, Deborah N. Huntzinger, Kevin Schaefer, Robert Cook, Yaxing Wei, Yuanyuan Fang, Daniel Hayes, Maoyi Huang, Atul Jain and Hanqin Tian

Artificial light at night as a new threat to pollination pp. 206-209

Eva Knop, Leana Zoller, Remo Ryser, Christopher Gerpe, Maurin Hörler and Colin Fontaine

Higher-order interactions stabilize dynamics in competitive network models pp. 210-213

Jacopo Grilli, György Barabás, Matthew J. Michalska-Smith and Stefano Allesina

Genetic origins of the Minoans and Mycenaeans pp. 214-218

Iosif Lazaridis, Alissa Mittnik, Nick Patterson, Swapan Mallick, Nadin Rohland, Saskia Pfrengle, Anja Furtwängler, Alexander Peltzer, Cosimo Posth, Andonis Vasilakis, P. J. P. McGeorge, Eleni Konsolaki-Yannopoulou, George Korres, Holley Martlew, Manolis Michalodimitrakis, Mehmet Özsait, Nesrin Özsait, Anastasia Papathanasiou, Michael Richards, Songül Alpaslan Roodenberg, Yannis Tzedakis, Robert Arnott, Daniel M. Fernandes, Jeffery R. Hughey, Dimitra M. Lotakis, Patrick A. Navas, Yannis Maniatis, John A. Stamatoyannopoulos, Kristin Stewardson, Philipp Stockhammer, Ron Pinhasi, David Reich, Johannes Krause and George Stamatoyannopoulos

Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells pp. 219-223

Jiho Choi, Aaron J. Huebner, Kendell Clement, Ryan M. Walsh, Andrej Savol, Kaixuan Lin, Hongcang Gu, Bruno Di Stefano, Justin Brumbaugh, Sang-Yong Kim, Jafar Sharif, Christopher M. Rose, Arman Mohammad, Junko Odajima, Jean Charron, Toshi Shioda, Andreas Gnirke, Steven Gygi, Haruhiko Koseki, Ruslan I. Sadreyev, Andrew Xiao, Alexander Meissner and Konrad Hochedlinger

Derivation of ground-state female ES cells maintaining gamete-derived DNA methylation pp. 224-227

Masaki Yagi, Satoshi Kishigami, Akito Tanaka, Katsunori Semi, Eiji Mizutani, Sayaka Wakayama, Teruhiko Wakayama, Takuya Yamamoto and Yasuhiro Yamada

Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism pp. 228-233

Tao Xu, Kelly M. Stewart, Xiaohu Wang, Kai Liu, Min Xie, Jae Kyu Ryu, Ke Li, Tianhua Ma, Haixia Wang, Lu Ni, Saiyong Zhu, Nan Cao, Dongwei Zhu, Yu Zhang, Katerina Akassoglou, Chen Dong, Edward M. Driggers and Sheng Ding

Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS pp. 234-238

Zhan Yao, Rona Yaeger, Vanessa S. Rodrik-Outmezguine, Anthony Tao, Neilawattie M. Torres, Matthew T. Chang, Matthias Drosten, Huiyong Zhao, Fabiola Cecchi, Todd Hembrough, Judith Michels, Hervé Baumert, Linde Miles, Naomi M. Campbell, Elisa de Stanchina, David B. Solit, Mariano Barbacid, Barry S. Taylor and Neal Rosen

A Braf kinase-inactive mutant induces lung adenocarcinoma pp. 239-243

Patricia Nieto, Chiara Ambrogio, Laura Esteban-Burgos, Gonzalo Gómez-López, María Teresa Blasco, Zhan Yao, Richard Marais, Neal Rosen, Roberto Chiarle, David G. Pisano, Mariano Barbacid and David Santamaría

Proteins evolve on the edge of supramolecular self-assembly pp. 244-247

Hector Garcia-Seisdedos, Charly Empereur-Mot, Nadav Elad and Emmanuel D. Levy

Funding: Austerity bites deeply pp. 249-251

Anna Petherick

Turning point: Galactic groundbreaker pp. 251-251

Virginia Gewin

Legale pp. 254-254

Vernor Vinge

2017, volume 548, articles 7665

On the role of H3.3 in retroviral silencing pp. E1-E3

Gernot Wolf, Rita Rebollo, Mohammad M. Karimi, Adam D. Ewing, Rui Kamada, Warren Wu, Brenda Wu, Mahesh Bachu, Keiko Ozato, Geoffrey J. Faulkner, Dixie L. Mager, Matthew C. Lorincz and Todd S. Macfarlan

Capitalize on African biodiversity pp. 7-7

Ameenah Gurib-Fakim

Elsässer et al. reply pp. E7-E9

Simon J. Elsässer, Kyung-Min Noh, Nichole Diaz, C. David Allis and Laura A. Banaszynski

CRISPR fixes disease gene in viable human embryos pp. 13-14

Heidi Ledford

Jordan stakes its future on science pp. 14-15

Amy Maxmen

Fears rise for US climate report as Trump officials take reins pp. 15-16

Jeff Tollefson

Big names in statistics want to shake up much-maligned P value pp. 16-17

Dalmeet Singh Chawla

Bacteria could be key to freeing South Pacific of mosquitoes pp. 17-18

Emma Marris

The race to reveal antimatter’s secrets pp. 20-23

Elizabeth Gibney

Prove Paris was more than paper promises pp. 25-27

David G. Victor, Keigo Akimoto, Yoichi Kaya, Mitsutsune Yamaguchi, Danny Cullenward and Cameron Hepburn

Summer books pp. 28-30

Sharon Weinberger, Louise Humphrey, Anne-Emanuelle Birn, Brad DeLong, Roger D. Launius, Michael Mann, Robert P. Crease and Marcus Munafò

More research won't crack misconduct pp. 31-31

Donald S. Kornfeld and Sandra L. Titus

GM-food regulations: engage the public pp. 31-31

Paul Enríquez

GM-food regulations: US agencies respond pp. 31-31

Jason Dietz, Laura Epstein and Sidney W. Abel

BaBar Collaboration first to see anomaly pp. 31-31

Tom Browder, Giovanni Passaleva and Michael Roney

Improve contactless sensing technology pp. 31-31

Ramesh G. Mani and Annika Kriisa

Angela M. Hartley Brodie (1934–2017) pp. 32-32

Balkees Abderrahman and V. Craig Jordan

The fastest-rotating fluid pp. 34-35

Hannah Petersen

Neurons couple up to make decisions pp. 35-36

Stephen V. David

Energy sensing through a sugar diphosphate pp. 36-37

Bruce E. Kemp and Jonathan S. Oakhill

Ozone-like layer in an exoplanet atmosphere pp. 38-39

Kevin Heng

Chimps at risk from anthrax pp. 38-38

Anna Armstrong

A precision approach to tumour treatment pp. 40-41

Rodrigo Dienstmann and Josep Tabernero

The evolution of the host microbiome as an ecosystem on a leash pp. 43-51

Kevin R. Foster, Jonas Schluter, Katharine Z. Coyte and Seth Rakoff-Nahoum

Hypothalamic stem cells control ageing speed partly through exosomal miRNAs pp. 52-57

Yalin Zhang, Min Soo Kim, Baosen Jia, Jingqi Yan, Juan Pablo Zuniga-Hertz, Cheng Han and Dongsheng Cai

An ultrahot gas-giant exoplanet with a stratosphere pp. 58-61

Thomas M. Evans, David K. Sing, Tiffany Kataria, Jayesh Goyal, Nikolay Nikolov, Hannah R. Wakeford, Drake Deming, Mark S. Marley, David S. Amundsen, Gilda E. Ballester, Joanna K. Barstow, Lotfi Ben-Jaffel, Vincent Bourrier, Lars A. Buchhave, Ofer Cohen, David Ehrenreich, Antonio García Muñoz, Gregory W. Henry, Heather Knutson, Panayotis Lavvas, Alain Lecavelier des Etangs, Nikole K. Lewis, Mercedes López-Morales, Avi M. Mandell, Jorge Sanz-Forcada, Pascal Tremblin and Roxana Lupu

Observation of the hyperfine spectrum of antihydrogen pp. 66-69

M. Ahmadi, B. X. R. Alves, C. J. Baker, W. Bertsche, E. Butler, A. Capra, C. Carruth, C. L. Cesar, M. Charlton, S. Cohen, R. Collister, S. Eriksson, A. Evans, N. Evetts, J. Fajans, T. Friesen, M. C. Fujiwara, D. R. Gill, A. Gutierrez, J. S. Hangst, W. N. Hardy, M. E. Hayden, C. A. Isaac, A. Ishida, M. A. Johnson, S. A. Jones, S. Jonsell, L. Kurchaninov, N. Madsen, M. Mathers, D. Maxwell, J. T. K. McKenna, S. Menary, J. M. Michan, T. Momose, J. J. Munich, P. Nolan, K. Olchanski, A. Olin, P. Pusa, C. Ø. Rasmussen, F. Robicheaux, R. L. Sacramento, M. Sameed, E. Sarid, D. M. Silveira, S. Stracka, G. Stutter, C. So, T. D. Tharp, J. E. Thompson, R. I. Thompson, D. P. van der Werf and J. S. Wurtele

Quantum simulation of a Fermi–Hubbard model using a semiconductor quantum dot array pp. 70-73

T. Hensgens, T. Fujita, L. Janssen, Xiao Li, C. J. Van Diepen, C. Reichl, W. Wegscheider, S. Das Sarma and L. M. K. Vandersypen

Visible-light-driven methane formation from CO2 with a molecular iron catalyst pp. 74-77

Heng Rao, Luciana C. Schmidt, Julien Bonin and Marc Robert

Elements of Eoarchean life trapped in mineral inclusions pp. 78-81

T. Hassenkam, M. P. Andersson, K. N. Dalby, D. M. A. Mackenzie and M. T. Rosing

Persistent anthrax as a major driver of wildlife mortality in a tropical rainforest pp. 82-86

Constanze Hoffmann, Fee Zimmermann, Roman Biek, Hjalmar Kuehl, Kathrin Nowak, Roger Mundry, Anthony Agbor, Samuel Angedakin, Mimi Arandjelovic, Anja Blankenburg, Gregory Brazolla, Katherine Corogenes, Emmanuel Couacy-Hymann, Tobias Deschner, Paula Dieguez, Karsten Dierks, Ariane Düx, Susann Dupke, Henk Eshuis, Pierre Formenty, Yisa Ginath Yuh, Annemarie Goedmakers, Jan F. Gogarten, Anne-Céline Granjon, Scott McGraw, Roland Grunow, John Hart, Sorrel Jones, Jessica Junker, John Kiang, Kevin Langergraber, Juan Lapuente, Kevin Lee, Siv Aina Leendertz, Floraine Léguillon, Vera Leinert, Therese Löhrich, Sergio Marrocoli, Kerstin Mätz-Rensing, Amelia Meier, Kevin Merkel, Sonja Metzger, Mizuki Murai, Svenja Niedorf, Hélène De Nys, Andreas Sachse, Joost van Schijndel, Ulla Thiesen, Els Ton, Doris Wu, Lothar H. Wieler, Christophe Boesch, Silke R. Klee, Roman M. Wittig, Sébastien Calvignac-Spencer and Fabian H. Leendertz

Sequencing and de novo assembly of 150 genomes from Denmark as a population reference pp. 87-91

Lasse Maretty, Jacob Malte Jensen, Bent Petersen, Jonas Andreas Sibbesen, Siyang Liu, Palle Villesen, Laurits Skov, Kirstine Belling, Christian Theil Have, Jose M. G. Izarzugaza, Marie Grosjean, Jette Bork-Jensen, Jakob Grove, Thomas D. Als, Shujia Huang, Yuqi Chang, Ruiqi Xu, Weijian Ye, Junhua Rao, Xiaosen Guo, Jihua Sun, Hongzhi Cao, Chen Ye, Johan van Beusekom, Thomas Espeseth, Esben Flindt, Rune M. Friborg, Anders E. Halager, Stephanie Le Hellard, Christina M. Hultman, Francesco Lescai, Shengting Li, Ole Lund, Peter Løngren, Thomas Mailund, Maria Luisa Matey-Hernandez, Ole Mors, Christian N. S. Pedersen, Thomas Sicheritz-Pontén, Patrick Sullivan, Ali Syed, David Westergaard, Rachita Yadav, Ning Li, Xun Xu, Torben Hansen, Anders Krogh, Lars Bolund, Thorkild I. A. Sørensen, Oluf Pedersen, Ramneek Gupta, Simon Rasmussen, Søren Besenbacher, Anders D. Børglum, Jun Wang, Hans Eiberg, Karsten Kristiansen, Søren Brunak and Mikkel Heide Schierup

Distinct timescales of population coding across cortex pp. 92-96

Caroline A. Runyan, Eugenio Piasini, Stefano Panzeri and Christopher D. Harvey

In vivo FRET–FLIM reveals cell-type-specific protein interactions in Arabidopsis roots pp. 97-102

Yuchen Long, Yvonne Stahl, Stefanie Weidtkamp-Peters, Marten Postma, Wenkun Zhou, Joachim Goedhart, María-Isabel Sánchez-Pérez, Theodorus W. J. Gadella, Rüdiger Simon, Ben Scheres and Ikram Blilou

Stimulation of functional neuronal regeneration from Müller glia in adult mice pp. 103-107

Nikolas L. Jorstad, Matthew S. Wilken, William N. Grimes, Stefanie G. Wohl, Leah S. VandenBosch, Takeshi Yoshimatsu, Rachel O. Wong, Fred Rieke and Thomas A. Reh

Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows pp. 108-111

Devin Sok, Khoa M. Le, Melissa Vadnais, Karen L. Saye-Francisco, Joseph G. Jardine, Jonathan L. Torres, Zachary T. Berndsen, Leopold Kong, Robyn Stanfield, Jennifer Ruiz, Alejandra Ramos, Chi-Hui Liang, Patricia L. Chen, Michael F. Criscitiello, Waithaka Mwangi, Ian A. Wilson, Andrew B. Ward, Vaughn V. Smider and Dennis R. Burton

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK pp. 112-116

Chen-Song Zhang, Simon A. Hawley, Yue Zong, Mengqi Li, Zhichao Wang, Alexander Gray, Teng Ma, Jiwen Cui, Jin-Wei Feng, Mingjiang Zhu, Yu-Qing Wu, Terytty Yang Li, Zhiyun Ye, Shu-Yong Lin, Huiyong Yin, Hai-Long Piao, D. Grahame Hardie and Sheng-Cai Lin

Complex cellular logic computation using ribocomputing devices pp. 117-121

Alexander A. Green, Jongmin Kim, Duo Ma, Pamela A. Silver, James J. Collins and Peng Yin

Correction: Corrigendum: Crystal structure of the GLP-1 receptor bound to a peptide agonist pp. 122-122

Ali Jazayeri, Mathieu Rappas, Alastair J. H. Brown, James Kean, James C. Errey, Nathan J. Robertson, Cédric Fiez-Vandal, Stephen P. Andrews, Miles Congreve, Andrea Bortolato, Jonathan S. Mason, Asma H. Baig, Iryna Teobald, Andrew S. Doré, Malcolm Weir, Robert M. Cooke and Fiona H. Marshall

Correction: Corrigendum: Modulating the therapeutic response of tumours to dietary serine and glycine starvation pp. 122-122

Oliver D. K. Maddocks, Dimitris Athineos, Eric C. Cheung, Pearl Lee, Tong Zhang, Niels J. F. van den Broek, Gillian M. Mackay, Christiaan F. Labuschagne, David Gay, Flore Kruiswijk, Julianna Blagih, David F. Vincent, Kirsteen J. Campbell, Fatih Ceteci, Owen J. Sansom, Karen Blyth and Karen H. Vousden

Cybersecurity for the travelling scientist pp. 123-124

Brian Owens

Training: A winning detour pp. 125-127

Chris Woolston

Turning point: Data miner pp. 127-127

Virginia Gewin

A life in the day of pp. 130-130

William Meikle