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2021, volume 590, articles 7847

Rich countries should tithe their vaccines pp. 529-529

Gavin Yamey

Touch down! NASA’s Mars landing sparks new era of exploration pp. 535-537

Alexandra Witze

Million-year-old mammoth genomes shatter record for oldest ancient DNA pp. 537-538

Ewen Callaway

COVID vaccines and safety: what the research says pp. 538-540

Ariana Remmel

Quantum network is step towards ultrasecure internet pp. 540-541

Davide Castelvecchi

Give African research participants more say in genomic data, say scientists pp. 542-542

Linda Nordling

Superspreading drives the COVID pandemic — and could help to tame it pp. 544-546

Dyani Lewis

George Carruthers (1939–2020) pp. 547-547

Angelina Callahan, Robert R. Meier and David H. DeVorkin

Eight priorities for calculating the social cost of carbon pp. 548-550

Gernot Wagner, David Anthoff, Maureen Cropper, Simon Dietz, Kenneth Gillingham, Ben Groom, J. Paul Kelleher, Frances C. Moore and James H. Stock

Oil licences undermine Norway’s ocean leadership pp. 551-551

Henrik Österblom and Robert Blasiak

OECD on climate finance: donors need to step up and enhance reporting pp. 551-551

Simon Buckle

Hertha Ayrton’s Nature obituary: a monument to sexism in science pp. 551-551

Danita Brandt

Physics in Africa: invest to reform and transform pp. 551-551

Shaaban Said Khalil

Signs of self-sustained inflammatory circuits in severe COVID pneumonia pp. 553-554

Kara J. Mould and William J. Janssen

Cells use loop extrusion to weave and tie the genome pp. 554-555

Leonid A. Mirny

Accelerator-based light sources get a boost pp. 556-557

Alexander Brynes

Mutation alters chromatin changes during injury response to drive cancer pp. 557-558

Dane Vassiliadis and Mark A. Dawson

Antimatter in the proton is more down than up pp. 559-560

Haiyan Gao

The asymmetry of antimatter in the proton pp. 561-565

J. Dove, B. Kerns, R. E. McClellan, S. Miyasaka, D. H. Morton, K. Nagai, S. Prasad, F. Sanftl, M. B. C. Scott, A. S. Tadepalli, C. A. Aidala, J. Arrington, C. Ayuso, C. L. Barker, C. N. Brown, W. C. Chang, A. Chen, D. C. Christian, B. P. Dannowitz, M. Daugherity, M. Diefenthaler, L. El Fassi, D. F. Geesaman, R. Gilman, Y. Goto, L. Guo, R. Guo, T. J. Hague, R. J. Holt, D. Isenhower, E. R. Kinney, N. Kitts, A. Klein, D. W. Kleinjan, Y. Kudo, C. Leung, P.-J. Lin, K. Liu, M. X. Liu, W. Lorenzon, N. C. R. Makins, M. Mesquita Medeiros, P. L. McGaughey, Y. Miyachi, I. Mooney, K. Nakahara, K. Nakano, S. Nara, J.-C. Peng, A. J. Puckett, B. J. Ramson, P. E. Reimer, J. G. Rubin, S. Sawada, T. Sawada, T.-A. Shibata, D. Su, M. Teo, B. G. Tice, R. S. Towell, S. Uemura, S. Watson, S. G. Wang, A. B. Wickes, J. Wu, Z. Xi and Z. Ye

Angular momentum generation in nuclear fission pp. 566-570

J. N. Wilson, D. Thisse, M. Lebois, N. Jovančević, D. Gjestvang, R. Canavan, M. Rudigier, D. Étasse, R-B. Gerst, L. Gaudefroy, E. Adamska, P. Adsley, A. Algora, M. Babo, K. Belvedere, J. Benito, G. Benzoni, A. Blazhev, A. Boso, S. Bottoni, M. Bunce, R. Chakma, N. Cieplicka-Oryńczak, S. Courtin, M. L. Cortés, P. Davies, C. Delafosse, M. Fallot, B. Fornal, L. Fraile, A. Gottardo, V. Guadilla, G. Häfner, K. Hauschild, M. Heine, C. Henrich, I. Homm, F. Ibrahim, Ł. W. Iskra, P. Ivanov, S. Jazrawi, A. Korgul, P. Koseoglou, T. Kröll, T. Kurtukian-Nieto, L. Meur, S. Leoni, J. Ljungvall, A. Lopez-Martens, R. Lozeva, I. Matea, K. Miernik, J. Nemer, S. Oberstedt, W. Paulsen, M. Piersa, Y. Popovitch, C. Porzio, L. Qi, D. Ralet, P. H. Regan, K. Rezynkina, V. Sánchez-Tembleque, S. Siem, C. Schmitt, P.-A. Söderström, C. Sürder, G. Tocabens, V. Vedia, D. Verney, N. Warr, B. Wasilewska, J. Wiederhold, M. Yavahchova, F. Zeiser and S. Ziliani

Deterministic multi-qubit entanglement in a quantum network pp. 571-575

Youpeng Zhong, Hung-Shen Chang, Audrey Bienfait, Étienne Dumur, Ming-Han Chou, Christopher R. Conner, Joel Grebel, Rhys G. Povey, Haoxiong Yan, David I. Schuster and Andrew N. Cleland

Experimental demonstration of the mechanism of steady-state microbunching pp. 576-579

Xiujie Deng, Alexander Chao, Jörg Feikes, Arne Hoehl, Wenhui Huang, Roman Klein, Arnold Kruschinski, Ji Li, Aleksandr Matveenko, Yuriy Petenev, Markus Ries, Chuanxiang Tang and Lixin Yan

First return, then explore pp. 580-586

Adrien Ecoffet, Joost Huizinga, Joel Lehman, Kenneth O. Stanley and Jeff Clune

Efficient perovskite solar cells via improved carrier management pp. 587-593

Jason J. Yoo, Gabkyung Seo, Matthew R. Chua, Tae Gwan Park, Yongli Lu, Fabian Rotermund, Young-Ki Kim, Chan Su Moon, Nam Joong Jeon, Juan-Pablo Correa-Baena, Vladimir Bulović, Seong Sik Shin, Moungi G. Bawendi and Jangwon Seo

Strong tough hydrogels via the synergy of freeze-casting and salting out pp. 594-599

Mutian Hua, Shuwang Wu, Yanfei Ma, Yusen Zhao, Zilin Chen, Imri Frenkel, Joseph Strzalka, Hua Zhou, Xinyuan Zhu and Ximin He

Genomic basis of geographical adaptation to soil nitrogen in rice pp. 600-605

Yongqiang Liu, Hongru Wang, Zhimin Jiang, Wei Wang, Ruineng Xu, Qihui Wang, Zhihua Zhang, Aifu Li, Yan Liang, Shujun Ou, Xiujie Liu, Shouyun Cao, Hongning Tong, Yonghong Wang, Feng Zhou, Hong Liao, Bin Hu and Chengcai Chu

Evolving schema representations in orbitofrontal ensembles during learning pp. 606-611

Jingfeng Zhou, Chunying Jia, Marlian Montesinos-Cartagena, Matthew P. H. Gardner, Wenhui Zong and Geoffrey Schoenbaum

Astrocytes phagocytose adult hippocampal synapses for circuit homeostasis pp. 612-617

Joon-Hyuk Lee, Ji-young Kim, Seulgi Noh, Hyoeun Lee, Se Young Lee, Ji Young Mun, Hyungju Park and Won-Suk Chung

Cooperative epithelial phagocytosis enables error correction in the early embryo pp. 618-623

Esteban Hoijman, Hanna-Maria Häkkinen, Queralt Tolosa-Ramon, Senda Jiménez-Delgado, Chris Wyatt, Marta Miret-Cuesta, Manuel Irimia, Andrew Callan-Jones, Stefan Wieser and Verena Ruprecht

The Card1 nuclease provides defence during type III CRISPR immunity pp. 624-629

Jakob T. Rostøl, Wei Xie, Vitaly Kuryavyi, Pascal Maguin, Kevin Kao, Ruby Froom, Dinshaw J. Patel and Luciano A. Marraffini

Correlates of protection against SARS-CoV-2 in rhesus macaques pp. 630-634

Katherine McMahan, Jingyou Yu, Noe B. Mercado, Carolin Loos, Lisa H. Tostanoski, Abishek Chandrashekar, Jinyan Liu, Lauren Peter, Caroline Atyeo, Alex Zhu, Esther A. Bondzie, Gabriel Dagotto, Makda S. Gebre, Catherine Jacob-Dolan, Zhenfeng Li, Felix Nampanya, Shivani Patel, Laurent Pessaint, Alex Ry, Kelvin Blade, Jake Yalley-Ogunro, Mehtap Cabus, Renita Brown, Anthony Cook, Elyse Teow, Hanne Andersen, Mark G. Lewis, Douglas A. Lauffenburger, Galit Alter and Dan H. Barouch

Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia pp. 635-641

Rogan A. Grant, Luisa Morales-Nebreda, Nikolay S. Markov, Suchitra Swaminathan, Melissa Querrey, Estefany R. Guzman, Darryl A. Abbott, Helen K. Donnelly, Alvaro Donayre, Isaac A. Goldberg, Zasu M. Klug, Nicole Borkowski, Ziyan Lu, Hermon Kihshen, Yuliya Politanska, Lango Sichizya, Mengjia Kang, Ali Shilatifard, Chao Qi, Jon W. Lomasney, A. Christine Argento, Jacqueline M. Kruser, Elizabeth S. Malsin, Chiagozie O. Pickens, Sean B. Smith, James M. Walter, Anna E. Pawlowski, Daniel Schneider, Prasanth Nannapaneni, Hiam Abdala-Valencia, Ankit Bharat, Cara J. Gottardi, G. R. Scott Budinger, Alexander V. Misharin, Benjamin D. Singer and Richard G. Wunderink

A gene–environment-induced epigenetic program initiates tumorigenesis pp. 642-648

Direna Alonso-Curbelo, Yu-Jui Ho, Cassandra Burdziak, Jesper L. V. Maag, John P. Morris, Rohit Chandwani, Hsuan-An Chen, Kaloyan M. Tsanov, Francisco M. Barriga, Wei Luan, Nilgun Tasdemir, Geulah Livshits, Elham Azizi, Jaeyoung Chun, John E. Wilkinson, Linas Mazutis, Steven D. Leach, Richard Koche, Dana Pe’er and Scott W. Lowe

Spatiotemporal dissection of the cell cycle with single-cell proteogenomics pp. 649-654

Diana Mahdessian, Anthony J. Cesnik, Christian Gnann, Frida Danielsson, Lovisa Stenström, Muhammad Arif, Cheng Zhang, Trang Le, Fredric Johansson, Rutger Schutten, Anna Bäckström, Ulrika Axelsson, Peter Thul, Nathan H. Cho, Oana Carja, Mathias Uhlén, Adil Mardinoglu, Charlotte Stadler, Cecilia Lindskog, Burcu Ayoglu, Manuel D. Leonetti, Fredrik Pontén, Devin P. Sullivan and Emma Lundberg

Tracking break-induced replication shows that it stalls at roadblocks pp. 655-659

Liping Liu, Zhenxin Yan, Beth A. Osia, Jerzy Twarowski, Luyang Sun, Juraj Kramara, Rosemary S. Lee, Sandeep Kumar, Rajula Elango, Hanzeng Li, Weiwei Dang, Grzegorz Ira and Anna Malkova

Loop extrusion as a mechanism for formation of DNA damage repair foci pp. 660-665

Coline Arnould, Vincent Rocher, Anne-Laure Finoux, Thomas Clouaire, Kevin Li, Felix Zhou, Pierre Caron, Philippe. E. Mangeot, Emiliano P. Ricci, Raphaël Mourad, James E. Haber, Daan Noordermeer and Gaëlle Legube

Functional refolding of the penetration protein on a non-enveloped virus pp. 666-670

Tobias Herrmann, Raúl Torres, Eric N. Salgado, Cristina Berciu, Daniel Stoddard, Daniela Nicastro, Simon Jenni and Stephen C. Harrison

Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly pp. 671-676

Daniel Horn-Ghetko, David T. Krist, J. Rajan Prabu, Kheewoong Baek, Monique P. C. Mulder, Maren Klügel, Daniel C. Scott, Huib Ovaa, Gary Kleiger and Brenda A. Schulman

Pay gap widens between female and male scientists in North America pp. 677-677

Chris Woolston

Science outreach in my mother tongue pp. 678-678

Ana Teles and Flávia Viana

Closing in on a complete human genome pp. 679-681

Michael Eisenstein

Taking graphene out of the laboratory and into the real world pp. 684-684

Chris Woolston

2021, volume 590, articles 7846

Concerns about phytoplankton bloom trends in global lakes pp. E35-E47

Lian Feng, Yanhui Dai, Xuejiao Hou, Yang Xu, Junguo Liu and Chunmiao Zheng

Reply to: Concerns about phytoplankton bloom trends in global lakes pp. E48-E50

Jeff C. Ho, Anna M. Michalak and Nima Pahlevan

Author Correction: Cortical response selectivity derives from strength in numbers of synapses pp. E51-E51

Benjamin Scholl, Connon I. Thomas, Melissa A. Ryan, Naomi Kamasawa and David Fitzpatrick

Author Correction: Structural basis of assembly of the human T cell receptor–CD3 complex pp. E52-E52

Dong De, Lvqin Zheng, Jianquan Lin, Bailing Zhang, Yuwei Zhu, Ningning Li, Shuangyu Xie, Yuhang Wang, Ning Gao and Zhiwei Huang

Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans pp. E53-E53

Konrad J. Karczewski, Laurent C. Francioli, Grace Tiao, Beryl B. Cummings, Jessica Alföldi, Qingbo Wang, Ryan L. Collins, Kristen M. Laricchia, Andrea Ganna, Daniel P. Birnbaum, Laura D. Gauthier, Harrison Brand, Matthew Solomonson, Nicholas A. Watts, Daniel Rhodes, Moriel Singer-Berk, Eleina M. England, Eleanor G. Seaby, Jack A. Kosmicki, Raymond K. Walters, Katherine Tashman, Yossi Farjoun, Eric Banks, Timothy Poterba, Arcturus Wang, Cotton Seed, Nicola Whiffin, Jessica X. Chong, Kaitlin E. Samocha, Emma Pierce-Hoffman, Zachary Zappala, Anne H. O’Donnell-Luria, Eric Vallabh Minikel, Ben Weisburd, Monkol Lek, James S. Ware, Christopher Vittal, Irina M. Armean, Louis Bergelson, Kristian Cibulskis, Kristen M. Connolly, Miguel Covarrubias, Stacey Donnelly, Steven Ferriera, Stacey Gabriel, Jeff Gentry, Namrata Gupta, Thibault Jeandet, Diane Kaplan, Christopher Llanwarne, Ruchi Munshi, Sam Novod, Nikelle Petrillo, David Roazen, Valentin Ruano-Rubio, Andrea Saltzman, Molly Schleicher, Jose Soto, Kathleen Tibbetts, Charlotte Tolonen, Gordon Wade, Michael E. Talkowski, Benjamin M. Neale, Mark J. Daly and Daniel G. MacArthur

Author Correction: Transcript expression-aware annotation improves rare variant interpretation pp. E54-E54

Beryl B. Cummings, Konrad J. Karczewski, Jack A. Kosmicki, Eleanor G. Seaby, Nicholas A. Watts, Moriel Singer-Berk, Jonathan M. Mudge, Juha Karjalainen, F. Kyle Satterstrom, Anne H. O’Donnell-Luria, Timothy Poterba, Cotton Seed, Matthew Solomonson, Jessica Alföldi, Mark J. Daly and Daniel G. MacArthur

Author Correction: A structural variation reference for medical and population genetics pp. E55-E55

Ryan L. Collins, Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli, Amit V. Khera, Chelsea Lowther, Laura D. Gauthier, Harold Wang, Nicholas A. Watts, Matthew Solomonson, Anne O’Donnell-Luria, Alexander Baumann, Ruchi Munshi, Mark Walker, Christopher W. Whelan, Yongqing Huang, Ted Brookings, Ted Sharpe, Matthew R. Stone, Elise Valkanas, Jack Fu, Grace Tiao, Kristen M. Laricchia, Valentin Ruano-Rubio, Christine Stevens, Namrata Gupta, Caroline Cusick, Lauren Margolin, Kent D. Taylor, Henry J. Lin, Stephen S. Rich, Wendy S. Post, Yii- Der Ida Chen, Jerome I. Rotter, Chad Nusbaum, Anthony Philippakis, Eric Lander, Stacey Gabriel, Benjamin M. Neale, Sekar Kathiresan, Mark J. Daly, Eric Banks, Daniel G. MacArthur and Michael E. Talkowski

Author Correction: Evaluating drug targets through human loss-of-function genetic variation pp. E56-E56

Eric Vallabh Minikel, Konrad J. Karczewski, Hilary C. Martin, Beryl B. Cummings, Nicola Whiffin, Daniel Rhodes, Jessica Alföldi, Richard C. Trembath, David A. Heel, Mark J. Daly, Stuart L. Schreiber and Daniel G. MacArthur

At 50, the UN Environment Programme must lead again pp. 365-365

Maria Ivanova

‘Major stones unturned’: COVID origin search must continue after WHO report, say scientists pp. 371-372

Smriti Mallapaty, Amy Maxmen and Ewen Callaway

Elation as first Arab Mars mission reaches orbit pp. 372-373

Elizabeth Gibney

Illegal CFC emissions have stopped since scientists raised alarm pp. 373-373

Jeff Tollefson

How ‘killer’ T cells could boost COVID immunity in face of new variants pp. 374-375

Heidi Ledford

Could mixing COVID vaccines boost immune response? pp. 375-376

Heidi Ledford

Neanderthal-like ‘mini-brains’ created in lab with CRISPR pp. 376-377

Ariana Remmel

This COVID-vaccine designer is tackling vaccine hesitancy — in churches and on Twitter pp. 377-377

Nidhi Subbaraman

Mystery gamma rays could help solve age-old lightning puzzle pp. 378-381

Elizabeth Gibney

The coronavirus is here to stay — here’s what that means pp. 382-384

Nicky Phillips

Variant-proof vaccines — invest now for the next pandemic pp. 386-388

Dennis R. Burton and Eric J. Topol

Involve citizens in climate-policy modelling pp. 389-389

Haris Doukas and Alexandros Nikas

Tech firms need Black AI scholars and labour rights pp. 389-389

Ifeoma Ajunwa, Sareeta Amrute, Lilly Irani, Winifred R. Poster and Meg Stalcup

Peace-making: new technologies are no panacea pp. 389-389

Oliver P. Richmond and Gëzim Visoka

Vaccination: keep records secure with blockchain pp. 389-389

Johnson Chun-Sing Cheung

High-performance plastic made from renewable oils is chemically recyclable by design pp. 391-392

Charlotte K. Williams and Georgina L. Gregory

The role and rule of relatedness in altruism pp. 392-394

Andrew F. G. Bourke

Multiple genomes give switchgrass an advantage pp. 394-395

Erik J. Sacks

Glowing nanocrystals enable 3D X-ray imaging pp. 396-397

Albano N. Carneiro Neto and Oscar L. Malta

Antibodies periodically wax and wane in survivors of Ebola pp. 397-398

Courtney Woolsey and Thomas W. Geisbert

An epigenetic tipping point in cancer comes under the microscope pp. 399-400

Martyna W. Sroka and Christopher R. Vakoc

Coherent X-ray−optical control of nuclear excitons pp. 401-404

Kilian P. Heeg, Andreas Kaldun, Cornelius Strohm, Christian Ott, Rajagopalan Subramanian, Dominik Lentrodt, Johann Haber, Hans-Christian Wille, Stephan Goerttler, Rudolf Rüffer, Christoph H. Keitel, Ralf Röhlsberger, Thomas Pfeifer and Jörg Evers

Localization of lattice dynamics in low-angle twisted bilayer graphene pp. 405-409

Andreij C. Gadelha, Douglas A. A. Ohlberg, Cassiano Rabelo, Eliel G. S. Neto, Thiago L. Vasconcelos, João L. Campos, Jessica S. Lemos, Vinícius Ornelas, Daniel Miranda, Rafael Nadas, Fabiano C. Santana, Kenji Watanabe, Takashi Taniguchi, Benoit Troeye, Michael Lamparski, Vincent Meunier, Viet-Hung Nguyen, Dawid Paszko, Jean-Christophe Charlier, Leonardo C. Campos, Luiz G. Cançado, Gilberto Medeiros-Ribeiro and Ado Jorio

High-resolution X-ray luminescence extension imaging pp. 410-415

Xiangyu Ou, Xian Qin, Bolong Huang, Jie Zan, Qinxia Wu, Zhongzhu Hong, Lili Xie, Hongyu Bian, Zhigao Yi, Xiaofeng Chen, Yiming Wu, Xiaorong Song, Juan Li, Qiushui Chen, Huanghao Yang and Xiaogang Liu

Self-similar mesocrystals form via interface-driven nucleation and assembly pp. 416-422

Guomin Zhu, Maria L. Sushko, John S. Loring, Benjamin A. Legg, Miao Song, Jennifer A. Soltis, Xiaopeng Huang, Kevin M. Rosso and James J. De Yoreo

Closed-loop recycling of polyethylene-like materials pp. 423-427

Manuel Häußler, Marcel Eck, Dario Rothauer and Stefan Mecking

A decline in global CFC-11 emissions during 2018−2019 pp. 428-432

Stephen A. Montzka, Geoffrey S. Dutton, Robert W. Portmann, Martyn P. Chipperfield, Sean Davis, Wuhu Feng, Alistair J. Manning, Eric Ray, Matthew Rigby, Bradley D. Hall, Carolina Siso, J. David Nance, Paul B. Krummel, Jens Mühle, Dickon Young, Simon O’Doherty, Peter K. Salameh, Christina M. Harth, Ronald G. Prinn, Ray F. Weiss, James W. Elkins, Helen Walter-Terrinoni and Christina Theodoridi

A decline in emissions of CFC-11 and related chemicals from eastern China pp. 433-437

Sunyoung Park, Luke M. Western, Takuya Saito, Alison L. Redington, Stephan Henne, Xuekun Fang, Ronald G. Prinn, Alistair J. Manning, Stephen A. Montzka, Paul J. Fraser, Anita L. Ganesan, Christina M. Harth, Jooil Kim, Paul B. Krummel, Qing Liang, Jens Mühle, Simon O’Doherty, Hyeri Park, Mi-Kyung Park, Stefan Reimann, Peter K. Salameh, Ray F. Weiss and Matthew Rigby

Genomic mechanisms of climate adaptation in polyploid bioenergy switchgrass pp. 438-444

John T. Lovell, Alice H. MacQueen, Sujan Mamidi, Jason Bonnette, Jerry Jenkins, Joseph D. Napier, Avinash Sreedasyam, Adam Healey, Adam Session, Shengqiang Shu, Kerrie Barry, Stacy Bonos, LoriBeth Boston, Christopher Daum, Shweta Deshpande, Aren Ewing, Paul P. Grabowski, Taslima Haque, Melanie Harrison, Jiming Jiang, Dave Kudrna, Anna Lipzen, Thomas H. Pendergast, Chris Plott, Peng Qi, Christopher A. Saski, Eugene V. Shakirov, David Sims, Manoj Sharma, Rita Sharma, Ada Stewart, Vasanth R. Singan, Yuhong Tang, Sandra Thibivillier, Jenell Webber, Xiaoyu Weng, Melissa Williams, Guohong Albert Wu, Yuko Yoshinaga, Matthew Zane, Li Zhang, Jiyi Zhang, Kathrine D. Behrman, Arvid R. Boe, Philip A. Fay, Felix B. Fritschi, Julie D. Jastrow, John Lloyd-Reilley, Juan Manuel Martínez-Reyna, Roser Matamala, Robert B. Mitchell, Francis M. Rouquette, Pamela Ronald, Malay Saha, Christian M. Tobias, Michael Udvardi, Rod A. Wing, Yanqi Wu, Laura E. Bartley, Michael Casler, Katrien M. Devos, David B. Lowry, Daniel S. Rokhsar, Jane Grimwood, Thomas E. Juenger and Jeremy Schmutz

A functional map for diverse forelimb actions within brainstem circuitry pp. 445-450

Ludwig Ruder, Riccardo Schina, Harsh Kanodia, Sara Valencia-Garcia, Chiara Pivetta and Silvia Arber

Cell-type-specific asynchronous modulation of PKA by dopamine in learning pp. 451-456

Suk Joon Lee, Bart Lodder, Yao Chen, Tommaso Patriarchi, Lin Tian and Bernardo L. Sabatini

In situ mapping identifies distinct vascular niches for myelopoiesis pp. 457-462

Jizhou Zhang, Qingqing Wu, Courtney B. Johnson, Giang Pham, Jeremy M. Kinder, Andre Olsson, Anastasiya Slaughter, Margot May, Benjamin Weinhaus, Angelo D’Alessandro, James Douglas Engel, Jean X. Jiang, J. Matthew Kofron, L. Frank Huang, V. B. Surya Prasath, Sing Sing Way, Nathan Salomonis, H. Leighton Grimes and Daniel Lucas

Molecular basis for control of antibiotic production by a bacterial hormone pp. 463-467

Shanshan Zhou, Hussain Bhukya, Nicolas Malet, Peter J. Harrison, Dean Rea, Matthew J. Belousoff, Hariprasad Venugopal, Paulina K. Sydor, Kathryn M. Styles, Lijiang Song, Max J. Cryle, Lona M. Alkhalaf, Vilmos Fülöp, Gregory L. Challis and Christophe Corre

Ebola virus antibody decay–stimulation in a high proportion of survivors pp. 468-472

Charlene Adaken, Janet T. Scott, Raman Sharma, Robin Gopal, Steven Dicks, Saidia Niazi, Samreen Ijaz, Tansy Edwards, Catherine C. Smith, Christine P. Cole, Philip Kamara, Osman Kargbo, Heidi A. Doughty, Johan Griensven, Peter W. Horby, Sahr M. Gevao, Foday Sahr, Richard J. Dimelow, Richard S. Tedder, Malcolm G. Semple, William A. Paxton and Georgios Pollakis

Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes pp. 473-479

Liliana M. Sanmarco, Michael A. Wheeler, Cristina Gutiérrez-Vázquez, Carolina Manganeli Polonio, Mathias Linnerbauer, Felipe A. Pinho-Ribeiro, Zhaorong Li, Federico Giovannoni, Katelyn V. Batterman, Giulia Scalisi, Stephanie E. J. Zandee, Evelyn S. Heck, Moneera Alsuwailm, Douglas L. Rosene, Burkhard Becher, Isaac M. Chiu, Alexandre Prat and Francisco J. Quintana

Creatine kinase B controls futile creatine cycling in thermogenic fat pp. 480-485

Janane F. Rahbani, Anna Roesler, Mohammed F. Hussain, Bozena Samborska, Christien B. Dykstra, Linus Tsai, Mark P. Jedrychowski, Laurent Vergnes, Karen Reue, Bruce M. Spiegelman and Lawrence Kazak

Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition pp. 486-491

Yael Cohen-Sharir, James M. McFarland, Mai Abdusamad, Carolyn Marquis, Sara V. Bernhard, Mariya Kazachkova, Helen Tang, Marica R. Ippolito, Kathrin Laue, Johanna Zerbib, Heidi L. H. Malaby, Andrew Jones, Lisa-Marie Stautmeister, Irena Bockaj, René Wardenaar, Nicholas Lyons, Ankur Nagaraja, Adam J. Bass, Diana C. J. Spierings, Floris Foijer, Rameen Beroukhim, Stefano Santaguida, Todd R. Golub, Jason Stumpff, Zuzana Storchová and Uri Ben-David

Whole-genome doubling confers unique genetic vulnerabilities on tumour cells pp. 492-497

Ryan J. Quinton, Amanda DiDomizio, Marc A. Vittoria, Kristýna Kotýnková, Carlos J. Ticas, Sheena Patel, Yusuke Koga, Jasmine Vakhshoorzadeh, Nicole Hermance, Taruho S. Kuroda, Neha Parulekar, Alison M. Taylor, Amity L. Manning, Joshua D. Campbell and Neil J. Ganem

Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases pp. 498-503

Wanqiu Li, Wei Tian, Gang Yuan, Pujuan Deng, Deepanwita Sengupta, Zhongjun Cheng, Yinghua Cao, Jiahao Ren, Yan Qin, Yuqiao Zhou, Yulin Jia, Or Gozani, Dinshaw J. Patel and Zhanxin Wang

Elevated NSD3 histone methylation activity drives squamous cell lung cancer pp. 504-508

Gang Yuan, Natasha M. Flores, Simone Hausmann, Shane M. Lofgren, Vladlena Kharchenko, Maria Angulo-Ibanez, Deepanwita Sengupta, Xiaoyin Lu, Iwona Czaban, Dulat Azhibek, Silvestre Vicent, Wolfgang Fischle, Mariusz Jaremko, Bingliang Fang, Ignacio I. Wistuba, Katrin F. Chua, Jack A. Roth, John D. Minna, Ning-Yi Shao, Łukasz Jaremko, Pawel K. Mazur and Or Gozani

Visualization of the mechanosensitive ion channel MscS under membrane tension pp. 509-514

Yixiao Zhang, Csaba Daday, Ruo-Xu Gu, Charles D. Cox, Boris Martinac, Bert L. Groot and Thomas Walz

How to shape a productive scientist–artist collaboration pp. 515-518

Virginia Gewin

‘All my art is curiosity-driven’: the garden studio where art and physics collide pp. 520-520

Amber Dance

2021, volume 590, articles 7845

Author Correction: Innervation of thermogenic adipose tissue via a calsyntenin 3β–S100b axis pp. E31-E33

Xing Zeng, Mengchen Ye, Jon M. Resch, Mark P. Jedrychowski, Bo Hu, Bradford B. Lowell, David D. Ginty and Bruce M. Spiegelman

Publisher Correction: VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours pp. E34-E34

Eric Song, Tianyang Mao, Huiping Dong, Ligia Simoes Braga Boisserand, Salli Antila, Marcus Bosenberg, Kari Alitalo, Jean-Leon Thomas and Akiko Iwasaki

Test behavioural nudges to boost COVID immunization pp. 185-185

Mitesh Patel

What’s the risk of dying from a fast-spreading COVID-19 variant? pp. 191-192

Smriti Mallapaty

Tracking QAnon: how Trump turned conspiracy-theory research upside down pp. 192-193

Jeff Tollefson

COVID’s mental-health toll: how scientists are tracking a surge in depression pp. 194-195

Alison Abbott

Scientists call for fully open sharing of coronavirus genome data pp. 195-196

Richard Van Noorden

AI maths whiz creates tough new problems for humans to solve pp. 196-196

Davide Castelvecchi

Vaccines are curbing COVID: Data from Israel show drop in infections pp. 197-197

Smriti Mallapaty

The broken promise that undermines human genome research pp. 198-201

Kendall Powell

Rapid coronavirus tests: a guide for the perplexed pp. 202-205

Giorgia Guglielmi

Outstanding reportage from the front lines of geoengineering pp. 206-207

Gaia Vince

Sequence three million genomes across Africa pp. 209-211

Ambroise Wonkam

A wealth of discovery built on the Human Genome Project — by the numbers pp. 212-215

Alexander J. Gates, Deisy Morselli Gysi, Manolis Kellis and Albert-László Barabási

Breaking through the unknowns of the human reference genome pp. 217-218

Karen H. Miga

How the human genome transformed study of rare diseases pp. 218-219

Fowzan S. Alkuraya

From one human genome to a complex tapestry of ancestry pp. 220-221

Charles N. Rotimi and Adebowale A. Adeyemo

New-found brake calibrates insulin action in β-cells pp. 221-223

Rohit N. Kulkarni

Neuroprosthetic device maintains blood pressure after spinal cord injury pp. 223-224

Patrice G. Guyenet

Lend an ear to a classic tale of mammalian evolution pp. 224-226

Simone Hoffmann

Shedding squeezed light on dark matter pp. 226-227

Igor G. Irastorza

Origins of modern human ancestry pp. 229-237

Anders Bergström, Chris Stringer, Mateja Hajdinjak, Eleanor M. L. Scerri and Pontus Skoglund

A quantum enhanced search for dark matter axions pp. 238-242

K. M. Backes, D. A. Palken, S. Al Kenany, B. M. Brubaker, S. B. Cahn, A. Droster, Gene C. Hilton, Sumita Ghosh, H. Jackson, S. K. Lamoreaux, A. F. Leder, K. W. Lehnert, S. M. Lewis, M. Malnou, R. H. Maruyama, N. M. Rapidis, M. Simanovskaia, Sukhman Singh, D. H. Speller, I. Urdinaran, Leila R. Vale, E. C. Assendelft, K. Bibber and H. Wang

Protecting a bosonic qubit with autonomous quantum error correction pp. 243-248

Jeffrey M. Gertler, Brian Baker, Juliang Li, Shruti Shirol, Jens Koch and Chen Wang

Tunable strongly coupled superconductivity in magic-angle twisted trilayer graphene pp. 249-255

Jeong Min Park, Yuan Cao, Kenji Watanabe, Takashi Taniguchi and Pablo Jarillo-Herrero

A universal 3D imaging sensor on a silicon photonics platform pp. 256-261

Christopher Rogers, Alexander Y. Piggott, David J. Thomson, Robert F. Wiser, Ion E. Opris, Steven A. Fortune, Andrew J. Compston, Alexander Gondarenko, Fanfan Meng, Xia Chen, Graham T. Reed and Remus Nicolaescu

Facile route to bulk ultrafine-grain steels for high strength and ductility pp. 262-267

Junheng Gao, Suihe Jiang, Huairuo Zhang, Yuhe Huang, Dikai Guan, Yidong Xu, Shaokang Guan, Leonid A. Bendersky, Albert V. Davydov, Yuan Wu, Huihui Zhu, Yandong Wang, Zhaoping Lu and W. Mark Rainforth

Thermally reconfigurable monoclinic nematic colloidal fluids pp. 268-274

Haridas Mundoor, Jin-Sheng Wu, Henricus H. Wensink and Ivan I. Smalyukh

Complex structures arising from the self-assembly of a simple organic salt pp. 275-278

Riccardo Montis, Luca Fusaro, Andrea Falqui, Michael B. Hursthouse, Nikolay Tumanov, Simon J. Coles, Terry L. Threlfall, Peter N. Horton, Rachid Sougrat, Anaïs Lafontaine, Gérard Coquerel and A. David Rae

A monotreme-like auditory apparatus in a Middle Jurassic haramiyidan pp. 279-283

Junyou Wang, John R. Wible, Bin Guo, Sarah L. Shelley, Han Hu and Shundong Bi

Giant lungfish genome elucidates the conquest of land by vertebrates pp. 284-289

Axel Meyer, Siegfried Schloissnig, Paolo Franchini, Kang Du, Joost M. Woltering, Iker Irisarri, Wai Yee Wong, Sergej Nowoshilow, Susanne Kneitz, Akane Kawaguchi, Andrej Fabrizius, Peiwen Xiong, Corentin Dechaud, Herman P. Spaink, Jean-Nicolas Volff, Oleg Simakov, Thorsten Burmester, Elly M. Tanaka and Manfred Schartl

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program pp. 290-299

Daniel Taliun, Daniel N. Harris, Michael D. Kessler, Jedidiah Carlson, Zachary A. Szpiech, Raul Torres, Sarah A. Gagliano Taliun, André Corvelo, Stephanie M. Gogarten, Hyun Min Kang, Achilleas N. Pitsillides, Jonathon LeFaive, Seung-been Lee, Xiaowen Tian, Brian L. Browning, Sayantan Das, Anne-Katrin Emde, Wayne E. Clarke, Douglas P. Loesch, Amol C. Shetty, Thomas W. Blackwell, Albert V. Smith, Quenna Wong, Xiaoming Liu, Matthew P. Conomos, Dean M. Bobo, François Aguet, Christine Albert, Alvaro Alonso, Kristin G. Ardlie, Dan E. Arking, Stella Aslibekyan, Paul L. Auer, John Barnard, R. Graham Barr, Lucas Barwick, Lewis C. Becker, Rebecca L. Beer, Emelia J. Benjamin, Lawrence F. Bielak, John Blangero, Michael Boehnke, Donald W. Bowden, Jennifer A. Brody, Esteban G. Burchard, Brian E. Cade, James F. Casella, Brandon Chalazan, Daniel I. Chasman, Yii- Der Ida Chen, Michael H. Cho, Seung Hoan Choi, Mina K. Chung, Clary B. Clish, Adolfo Correa, Joanne E. Curran, Brian Custer, Dawood Darbar, Michelle Daya, Mariza Andrade, Dawn L. DeMeo, Susan K. Dutcher, Patrick T. Ellinor, Leslie S. Emery, Celeste Eng, Diane Fatkin, Tasha Fingerlin, Lukas Forer, Myriam Fornage, Nora Franceschini, Christian Fuchsberger, Stephanie M. Fullerton, Soren Germer, Mark T. Gladwin, Daniel J. Gottlieb, Xiuqing Guo, Michael E. Hall, Jiang He, Nancy L. Heard-Costa, Susan R. Heckbert, Marguerite R. Irvin, Jill M. Johnsen, Andrew D. Johnson, Robert Kaplan, Sharon L. R. Kardia, Tanika Kelly, Shannon Kelly, Eimear E. Kenny, Douglas P. Kiel, Robert Klemmer, Barbara A. Konkle, Charles Kooperberg, Anna Köttgen, Leslie A. Lange, Jessica Lasky-Su, Daniel Levy, Xihong Lin, Keng-Han Lin, Chunyu Liu, Ruth J. F. Loos, Lori Garman, Robert Gerszten, Steven A. Lubitz, Kathryn L. Lunetta, Angel C. Y. Mak, Ani Manichaikul, Alisa K. Manning, Rasika A. Mathias, David D. McManus, Stephen T. McGarvey, James B. Meigs, Deborah A. Meyers, Julie L. Mikulla, Mollie A. Minear, Braxton D. Mitchell, Sanghamitra Mohanty, May E. Montasser, Courtney Montgomery, Alanna C. Morrison, Joanne M. Murabito, Andrea Natale, Pradeep Natarajan, Sarah C. Nelson, Kari E. North, Jeffrey R. O’Connell, Nicholette D. Palmer, Nathan Pankratz, Gina M. Peloso, Patricia A. Peyser, Jacob Pleiness, Wendy S. Post, Bruce M. Psaty, D. C. Rao, Susan Redline, Alexander P. Reiner, Dan Roden, Jerome I. Rotter, Ingo Ruczinski, Chloé Sarnowski, Sebastian Schoenherr, David A. Schwartz, Jeong-Sun Seo, Sudha Seshadri, Vivien A. Sheehan, Wayne H. Sheu, M. Benjamin Shoemaker, Nicholas L. Smith, Jennifer A. Smith, Nona Sotoodehnia, Adrienne M. Stilp, Weihong Tang, Kent D. Taylor, Marilyn Telen, Timothy A. Thornton, Russell P. Tracy, David J. Berg, Ramachandran S. Vasan, Karine A. Viaud-Martinez, Scott Vrieze, Daniel E. Weeks, Bruce S. Weir, Scott T. Weiss, Lu-Chen Weng, Cristen J. Willer, Yingze Zhang, Xutong Zhao, Donna K. Arnett, Allison E. Ashley-Koch, Kathleen C. Barnes, Eric Boerwinkle, Stacey Gabriel, Richard Gibbs, Kenneth M. Rice, Stephen S. Rich, Edwin K. Silverman, Pankaj Qasba, Weiniu Gan, George J. Papanicolaou, Deborah A. Nickerson, Sharon R. Browning, Michael C. Zody, Sebastian Zöllner, James G. Wilson, L. Adrienne Cupples, Cathy C. Laurie, Cashell E. Jaquish, Ryan D. Hernandez, Timothy D. O’Connor and Gonçalo R. Abecasis

Regulatory genomic circuitry of human disease loci by integrative epigenomics pp. 300-307

Carles A. Boix, Benjamin T. James, Yongjin P. Park, Wouter Meuleman and Manolis Kellis

Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury pp. 308-314

Jordan W. Squair, Matthieu Gautier, Lois Mahe, Jan Elaine Soriano, Andreas Rowald, Arnaud Bichat, Newton Cho, Mark A. Anderson, Nicholas D. James, Jerome Gandar, Anthony V. Incognito, Giuseppe Schiavone, Zoe K. Sarafis, Achilleas Laskaratos, Kay Bartholdi, Robin Demesmaeker, Salif Komi, Charlotte Moerman, Bita Vaseghi, Berkeley Scott, Ryan Rosentreter, Claudia Kathe, Jimmy Ravier, Laura McCracken, Xiaoyang Kang, Nicolas Vachicouras, Florian Fallegger, Ileana Jelescu, YunLong Cheng, Qin Li, Rik Buschman, Nicolas Buse, Tim Denison, Sean Dukelow, Rebecca Charbonneau, Ian Rigby, Steven K. Boyd, Philip J. Millar, Eduardo Martin Moraud, Marco Capogrosso, Fabien B. Wagner, Quentin Barraud, Erwan Bezard, Stéphanie P. Lacour, Jocelyne Bloch, Grégoire Courtine and Aaron A. Phillips

Antidepressant actions of ketamine engage cell-specific translation via eIF4E pp. 315-319

Argel Aguilar-Valles, Danilo De Gregorio, Edna Matta-Camacho, Mohammad J. Eslamizade, Abdessattar Khlaifia, Agnieszka Skaleka, Martha Lopez-Canul, Angelica Torres-Berrio, Sara Bermudez, Gareth M. Rurak, Stephanie Simard, Natalina Salmaso, Gabriella Gobbi, Jean-Claude Lacaille and Nahum Sonenberg

A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate pp. 320-325

Lorena Sanchez-Felipe, Thomas Vercruysse, Sapna Sharma, Ji Ma, Viktor Lemmens, Dominique Van Looveren, Mahadesh Prasad Arkalagud Javarappa, Robbert Boudewijns, Bert Malengier-Devlies, Laurens Liesenborghs, Suzanne J. F. Kaptein, Carolien De Keyzer, Lindsey Bervoets, Sarah Debaveye, Madina Rasulova, Laura Seldeslachts, Li-Hsin Li, Sander Jansen, Michael Bright Yakass, Babs E. Verstrepen, Kinga P. Böszörményi, Gwendoline Kiemenyi-Kayere, Nikki van Driel, Osbourne Quaye, Xin Zhang, Sebastiaan ter Horst, Niraj Mishra, Ward Deboutte, Jelle Matthijnssens, Lotte Coelmont, Corinne Vandermeulen, Elisabeth Heylen, Valentijn Vergote, Dominique Schols, Zhongde Wang, Willy Bogers, Thijs Kuiken, Ernst Verschoor, Christopher Cawthorne, Koen Van Laere, Ghislain Opdenakker, Greetje Vande Velde, Birgit Weynand, Dirk E. Teuwen, Patrick Matthys, Johan Neyts, Hendrik Thibaut and Kai Dallmeier

Inceptor counteracts insulin signalling in β-cells to control glycaemia pp. 326-331

Ansarullah, Chirag Jain, Fataneh Fathi Far, Sarah Homberg, Katharina Wißmiller, Felizitas Gräfin Hahn, Aurelia Raducanu, Silvia Schirge, Michael Sterr, Sara Bilekova, Johanna Siehler, Julius Wiener, Lena Oppenländer, Amir Morshedi, Aimée Bastidas-Ponce, Gustav Collden, Martin Irmler, Johannes Beckers, Annette Feuchtinger, Michal Grzybek, Christin Ahlbrecht, Regina Feederle, Oliver Plettenburg, Timo D. Müller, Matthias Meier, Matthias H. Tschöp, Ünal Coskun and Heiko Lickert

Anti-tumour immunity induces aberrant peptide presentation in melanoma pp. 332-337

Osnat Bartok, Abhijeet Pataskar, Remco Nagel, Maarja Laos, Eden Goldfarb, Deborah Hayoun, Ronen Levy, Pierre-Rene Körner, Inger Z. M. Kreuger, Julien Champagne, Esther A. Zaal, Onno B. Bleijerveld, Xinyao Huang, Juliana Kenski, Jennifer Wargo, Alexander Brandis, Yishai Levin, Orel Mizrahi, Michal Alon, Sacha Lebon, Weiwen Yang, Morten M. Nielsen, Noam Stern-Ginossar, Maarten Altelaar, Celia R. Berkers, Tamar Geiger, Daniel S. Peeper, Johanna Olweus, Yardena Samuels and Reuven Agami

Loop extrusion mediates physiological Igh locus contraction for RAG scanning pp. 338-343

Hai-Qiang Dai, Hongli Hu, Jiangman Lou, Adam Yongxin Ye, Zhaoqing Ba, Xuefei Zhang, Yiwen Zhang, Lijuan Zhao, Hye Suk Yoon, Aimee M. Chapdelaine-Williams, Nia Kyritsis, Huan Chen, Kerstin Johnson, Sherry Lin, Andrea Conte, Rafael Casellas, Cheng-Sheng Lee and Frederick W. Alt

Integrated spatial genomics reveals global architecture of single nuclei pp. 344-350

Yodai Takei, Jina Yun, Shiwei Zheng, Noah Ollikainen, Nico Pierson, Jonathan White, Sheel Shah, Julian Thomassie, Shengbao Suo, Chee-Huat Linus Eng, Mitchell Guttman, Guo-Cheng Yuan and Long Cai

How the arts can help you to craft a successful research career pp. 351-353

Amber Dance

Building a university to deliver work-ready engineers pp. 356-356

Chris Woolston

2021, volume 590, articles 7844

Issues with combining incompatible and sterile insect techniques pp. E1-E2

Riccardo Moretti and Maurizio Calvitti

Reply to: Issues with combining incompatible and sterile insect techniques pp. E3-E5

Yongjun Li, Luke Anthony Baton, Dongjing Zhang, Jérémy Bouyer, Andrew G. Parker, Ary A. Hoffmann, Lee Ching Ng, Cheong Huat Tan and Zhiyong Xi

On the measured dielectric constant of amorphous boron nitride pp. E6-E7

Lei Li and Xiang Ming Chen

Reply to: On the measured dielectric constant of amorphous boron nitride pp. E8-E10

Seokmo Hong, Min-Hyun Lee, Sang Won Kim, Chang-Seok Lee, Kyung Yeol Ma, Gwangwoo Kim, Seong In Yoon, Aleandro Antidormi, Stephan Roche, Hyeon-Jin Shin, Manish Chhowalla and Hyeon Suk Shin

Rethink how we plan research to shrink COVID health disparities pp. 9-9

Lisa Cooper

Author Correction: Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’ pp. E11-E11

Enrico Lavezzo, Elisa Franchin, Constanze Ciavarella, Gina Cuomo-Dannenburg, Luisa Barzon, Claudia Vecchio, Lucia Rossi, Riccardo Manganelli, Arianna Loregian, Nicolò Navarin, Davide Abate, Manuela Sciro, Stefano Merigliano, Ettore Canale, Maria Cristina Vanuzzo, Valeria Besutti, Francesca Saluzzo, Francesco Onelia, Monia Pacenti, Saverio G. Parisi, Giovanni Carretta, Daniele Donato, Luciano Flor, Silvia Cocchio, Giulia Masi, Alessandro Sperduti, Lorenzo Cattarino, Renato Salvador, Michele Nicoletti, Federico Caldart, Gioele Castelli, Eleonora Nieddu, Beatrice Labella, Ludovico Fava, Matteo Drigo, Katy A. M. Gaythorpe, Alessandra R. Brazzale, Stefano Toppo, Marta Trevisan, Vincenzo Baldo, Christl A. Donnelly, Neil M. Ferguson, Ilaria Dorigatti and Andrea Crisanti

Author Correction: Clustered versus catastrophic global vertebrate declines pp. E12-E12

Brian Leung, Anna L. Hargreaves, Dan A. Greenberg, Brian McGill, Maria Dornelas and Robin Freeman

Publisher Correction: Stellar clustering shapes the architecture of planetary systems pp. E14-E14

Andrew J. Winter, J. M. Diederik Kruijssen, Steven N. Longmore and Mélanie Chevance

How to redesign COVID vaccines so they protect against variants pp. 15-16

Ewen Callaway and Heidi Ledford

Publisher Correction: Integrated optical multi-ion quantum logic pp. E15-E15

Karan K. Mehta, Chi Zhang, Maciej Malinowski, Thanh-Long Nguyen, Martin Stadler and Jonathan P. Home

Publisher Correction: Filling metal–organic framework mesopores with TiO2 for CO2 photoreduction pp. E16-E16

Zhuo Jiang, Xiaohui Xu, Yanhang Ma, Hae Sung Cho, Deng Ding, Chao Wang, Jie Wu, Peter Oleynikov, Mei Jia, Jun Cheng, Yi Zhou, Osamu Terasaki, Tianyou Peng, Ling Zan and Hexiang Deng

Publisher Correction: COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses pp. E17-E17

Ugur Sahin, Alexander Muik, Evelyna Derhovanessian, Isabel Vogler, Lena M. Kranz, Mathias Vormehr, Alina Baum, Kristen Pascal, Jasmin Quandt, Daniel Maurus, Sebastian Brachtendorf, Verena Lörks, Julian Sikorski, Rolf Hilker, Dirk Becker, Ann-Kathrin Eller, Jan Grützner, Carsten Boesler, Corinna Rosenbaum, Marie-Cristine Kühnle, Ulrich Luxemburger, Alexandra Kemmer-Brück, David Langer, Martin Bexon, Stefanie Bolte, Katalin Karikó, Tania Palanche, Boris Fischer, Armin Schultz, Pei-Yong Shi, Camila Fontes-Garfias, John L. Perez, Kena A. Swanson, Jakob Loschko, Ingrid L. Scully, Mark Cutler, Warren Kalina, Christos A. Kyratsous, David Cooper, Philip R. Dormitzer, Kathrin U. Jansen and Özlem Türeci

Novavax offers first evidence that COVID vaccines protect people against variants pp. 17-17

Ewen Callaway and Smriti Mallapaty

Biden’s ambitious COVID plan: what scientists think pp. 18-19

Amy Maxmen and Nidhi Subbaraman

Publisher Correction: Seismic evidence for partial melt below tectonic plates pp. E18-E18

Eric Debayle, Thomas Bodin, Stéphanie Durand and Yanick Ricard

Life on Venus claim faces strongest challenge yet pp. 19-20

Alexandra Witze

Publisher Correction: Integrated multi-wavelength control of an ion qubit pp. E19-E19

R. J. Niffenegger, J. Stuart, C. Sorace-Agaskar, D. Kharas, S. Bramhavar, C. D. Bruzewicz, W. Loh, R. T. Maxson, R. McConnell, D. Reens, G. N. West, J. M. Sage and J. Chiaverini

Publisher Correction: The genomic landscapes of individual melanocytes from human skin pp. E20-E20

Jessica Tang, Eleanor Fewings, Darwin Chang, Hanlin Zeng, Shanshan Liu, Aparna Jorapur, Rachel L. Belote, Andrew S. McNeal, Tuyet M. Tan, Iwei Yeh, Sarah T. Arron, Robert L. Judson-Torres, Boris C. Bastian and A. Hunter Shain

Famed Chinese immunologist cleared of plagiarism and fraud pp. 20-21

David Cyranoski

Publisher Correction: Toughening mechanisms of the elytra of the diabolical ironclad beetle pp. E21-E21

Jesus Rivera, Maryam Sadat Hosseini, David Restrepo, Satoshi Murata, Drago Vasile, Dilworth Y. Parkinson, Harold S. Barnard, Atsushi Arakaki, Pablo Zavattieri and David Kisailus

How gut microbes could drive brain disorders pp. 22-25

Cassandra Willyard

Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures pp. E22-E22

Kenneth H. Dinnon, Sarah R. Leist, Alexandra Schäfer, Caitlin E. Edwards, David R. Martinez, Stephanie A. Montgomery, Ande West, Boyd L. Yount, Yixuan J. Hou, Lily E. Adams, Kendra L. Gully, Ariane J. Brown, Emily Huang, Matthew D. Bryant, Ingrid C. Choong, Jeffrey S. Glenn, Lisa E. Gralinski, Timothy P. Sheahan and Ralph S. Baric

Publisher Correction: A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity pp. E23-E23

Jingyun Yang, Wei Wang, Zimin Chen, Shuaiyao Lu, Fanli Yang, Zhenfei Bi, Linlin Bao, Fei Mo, Xue Li, Yong Huang, Weiqi Hong, Yun Yang, Yuan Zhao, Fei Ye, Sheng Lin, Wei Deng, Hua Chen, Hong Lei, Ziqi Zhang, Min Luo, Hong Gao, Yue Zheng, Yanqiu Gong, Xiaohua Jiang, Yanfeng Xu, Qi Lv, Dan Li, Manni Wang, Fengdi Li, Shunyi Wang, Guanpeng Wang, Pin Yu, Yajin Qu, Li Yang, Hongxin Deng, Aiping Tong, Jiong Li, Zhenling Wang, Jinliang Yang, Guobo Shen, Zhiwei Zhao, Yuhua Li, Jingwen Luo, Hongqi Liu, Wenhai Yu, Mengli Yang, Jingwen Xu, Junbin Wang, Haiyan Li, Haixuan Wang, Dexuan Kuang, Panpan Lin, Zhengtao Hu, Wei Guo, Wei Cheng, Yanlin He, Xiangrong Song, Chong Chen, Zhihong Xue, Shaohua Yao, Lu Chen, Xuelei Ma, Siyuan Chen, Maling Gou, Weijin Huang, Youchun Wang, Changfa Fan, Zhixin Tian, Ming Shi, Fu-Sheng Wang, Lunzhi Dai, Min Wu, Gen Li, Guangyu Wang, Yong Peng, Zhiyong Qian, Canhua Huang, Johnson Yiu-Nam Lau, Zhenglin Yang, Yuquan Wei, Xiaobo Cen, Xiaozhong Peng, Chuan Qin, Kang Zhang, Guangwen Lu and Xiawei Wei

Publisher Correction: ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques pp. E24-E24

Neeltje Doremalen, Teresa Lambe, Alexandra Spencer, Sandra Belij-Rammerstorfer, Jyothi N. Purushotham, Julia R. Port, Victoria A. Avanzato, Trenton Bushmaker, Amy Flaxman, Marta Ulaszewska, Friederike Feldmann, Elizabeth R. Allen, Hannah Sharpe, Jonathan Schulz, Myndi Holbrook, Atsushi Okumura, Kimberly Meade-White, Lizzette Pérez-Pérez, Nick J. Edwards, Daniel Wright, Cameron Bissett, Ciaran Gilbride, Brandi N. Williamson, Rebecca Rosenke, Dan Long, Alka Ishwarbhai, Reshma Kailath, Louisa Rose, Susan Morris, Claire Powers, Jamie Lovaglio, Patrick W. Hanley, Dana Scott, Greg Saturday, Emmie Wit, Sarah C. Gilbert and Vincent J. Munster

Publisher Correction: Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques pp. E25-E25

Noe B. Mercado, Roland Zahn, Frank Wegmann, Carolin Loos, Abishek Chandrashekar, Jingyou Yu, Jinyan Liu, Lauren Peter, Katherine McMahan, Lisa H. Tostanoski, Xuan He, David R. Martinez, Lucy Rutten, Rinke Bos, Danielle Manen, Jort Vellinga, Jerome Custers, Johannes P. Langedijk, Ted Kwaks, Mark J. G. Bakkers, David Zuijdgeest, Sietske K. Rosendahl Huber, Caroline Atyeo, Stephanie Fischinger, John S. Burke, Jared Feldman, Blake M. Hauser, Timothy M. Caradonna, Esther A. Bondzie, Gabriel Dagotto, Makda S. Gebre, Emily Hoffman, Catherine Jacob-Dolan, Marinela Kirilova, Zhenfeng Li, Zijin Lin, Shant H. Mahrokhian, Lori F. Maxfield, Felix Nampanya, Ramya Nityanandam, Joseph P. Nkolola, Shivani Patel, John D. Ventura, Kaylee Verrington, Huahua Wan, Laurent Pessaint, Alex Ry, Kelvin Blade, Amanda Strasbaugh, Mehtap Cabus, Renita Brown, Anthony Cook, Serge Zouantchangadou, Elyse Teow, Hanne Andersen, Mark G. Lewis, Yongfei Cai, Bing Chen, Aaron G. Schmidt, R. Keith Reeves, Ralph S. Baric, Douglas A. Lauffenburger, Galit Alter, Paul Stoffels, Mathai Mammen, Johan Hoof, Hanneke Schuitemaker and Dan H. Barouch

Publisher Correction: Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults pp. E26-E26

Mark J. Mulligan, Kirsten E. Lyke, Nicholas Kitchin, Judith Absalon, Alejandra Gurtman, Stephen Lockhart, Kathleen Neuzil, Vanessa Raabe, Ruth Bailey, Kena A. Swanson, Ping Li, Kenneth Koury, Warren Kalina, David Cooper, Camila Fontes-Garfias, Pei-Yong Shi, Özlem Türeci, Kristin R. Tompkins, Edward E. Walsh, Robert Frenck, Ann R. Falsey, Philip R. Dormitzer, William C. Gruber, Uğur Şahin and Kathrin U. Jansen

COVID-19 rarely spreads through surfaces. So why are we still deep cleaning? pp. 26-28

Dyani Lewis

Publisher Correction: Immune-evasive human islet-like organoids ameliorate diabetes pp. E27-E27

Eiji Yoshihara, Carolyn O’Connor, Emanuel Gasser, Zong Wei, Tae Gyu Oh, Tiffany W. Tseng, Dan Wang, Fritz Cayabyab, Yang Dai, Ruth T. Yu, Christopher Liddle, Annette R. Atkins, Michael Downes and Ronald M. Evans

Publisher Correction: A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation pp. E28-E28

Shantha K. Mahadevaiah, Mahesh N. Sangrithi, Takayuki Hirota and James M. A. Turner

Publisher Correction: Regulation of the MLH1–MLH3 endonuclease in meiosis pp. E29-E29

Elda Cannavo, Aurore Sanchez, Roopesh Anand, Lepakshi Ranjha, Jannik Hugener, Céline Adam, Ananya Acharya, Nicolas Weyland, Xavier Aran-Guiu, Jean-Baptiste Charbonnier, Eva R. Hoffmann, Valérie Borde, Joao Matos and Petr Cejka

Rogue antibodies could be driving severe COVID-19 pp. 29-31

Roxanne Khamsi

Publisher Correction: PCNA activates the MutLγ endonuclease to promote meiotic crossing over pp. E30-E30

Dhananjaya S. Kulkarni, Shannon N. Owens, Masayoshi Honda, Masaru Ito, Ye Yang, Mary W. Corrigan, Lan Chen, Aric L. Quan and Neil Hunter

Q&A: How cartoonists skewer tensions between science and society pp. 33-35

Alexandra Witze

The key to social change, free will on trial, and an astrophysicist on a visit from extraterrestrials: Books in brief pp. 35-35

Andrew Robinson

TL;DR: how well do machines summarize our work? pp. 36-36

James P. Bagrow

Open access pay-for-review option — ethical question pp. 36-36

Silvo Conticello

Vaccine sprint predicted a decade ago pp. 36-36

Rino Rappuoli

COVID-19 vaccines: call for global push to maintain efficacy pp. 36-36

Klaus Stöhr and Nancy Cox

The Arctic Ocean might have been filled with freshwater during ice ages pp. 37-38

Sharon Hoffmann

An estimation of undetected COVID cases in France pp. 38-39

Jeffrey Shaman

Machine learning made easy for optimizing chemical reactions pp. 40-41

Jason E. Hein

Food for thought about the immune drivers of gut pain pp. 41-43

Stuart M. Brierley

A molecular handbook for human development pp. 43-44

Felicia Kuperwaser and Itai Yanai

Reversal of immune-cell shutdown protects the ageing brain pp. 44-45

Jonas J. Neher

Developing fibrillated cellulose as a sustainable technological material pp. 47-56

Tian Li, Chaoji Chen, Alexandra H. Brozena, J. Y. Zhu, Lixian Xu, Carlos Driemeier, Jiaqi Dai, Orlando J. Rojas, Akira Isogai, Lars Wågberg and Liangbing Hu

Function and regulation of the divisome for mitochondrial fission pp. 57-66

Felix Kraus, Krishnendu Roy, Thomas J. Pucadyil and Michael T. Ryan

Generating conjectures on fundamental constants with the Ramanujan Machine pp. 67-73

Gal Raayoni, Shahar Gottlieb, Yahel Manor, George Pisha, Yoav Harris, Uri Mendlovic, Doron Haviv, Yaron Hadad and Ido Kaminer

Antiferromagnetic half-skyrmions and bimerons at room temperature pp. 74-79

Hariom Jani, Jheng-Cyuan Lin, Jiahao Chen, Jack Harrison, Francesco Maccherozzi, Jonathon Schad, Saurav Prakash, Chang-Beom Eom, A. Ariando, T. Venkatesan and Paolo G. Radaelli

Viscoelastic control of spatiotemporal order in bacterial active matter pp. 80-84

Song Liu, Suraj Shankar, M. Cristina Marchetti and Yilin Wu

Structural and spectroscopic characterization of an einsteinium complex pp. 85-88

Korey P. Carter, Katherine M. Shield, Kurt F. Smith, Zachary R. Jones, Jennifer N. Wacker, Leticia Arnedo-Sanchez, Tracy M. Mattox, Liane M. Moreau, Karah E. Knope, Stosh A. Kozimor, Corwin H. Booth and Rebecca J. Abergel

Bayesian reaction optimization as a tool for chemical synthesis pp. 89-96

Benjamin J. Shields, Jason Stevens, Jun Li, Marvin Parasram, Farhan Damani, Jesus I. Martinez Alvarado, Jacob M. Janey, Ryan P. Adams and Abigail G. Doyle

Glacial episodes of a freshwater Arctic Ocean covered by a thick ice shelf pp. 97-102

Walter Geibert, Jens Matthiessen, Ingrid Stimac, Jutta Wollenburg and Ruediger Stein

A genetic history of the pre-contact Caribbean pp. 103-110

Daniel M. Fernandes, Kendra A. Sirak, Harald Ringbauer, Jakob Sedig, Nadin Rohland, Olivia Cheronet, Matthew Mah, Swapan Mallick, Iñigo Olalde, Brendan J. Culleton, Nicole Adamski, Rebecca Bernardos, Guillermo Bravo, Nasreen Broomandkhoshbacht, Kimberly Callan, Francesca Candilio, Lea Demetz, Kellie Sara Duffett Carlson, Laurie Eccles, Suzanne Freilich, Richard J. George, Ann Marie Lawson, Kirsten Mandl, Fabio Marzaioli, Weston C. McCool, Jonas Oppenheimer, Kadir T. Özdogan, Constanze Schattke, Ryan Schmidt, Kristin Stewardson, Filippo Terrasi, Fatma Zalzala, Carlos Arredondo Antúnez, Ercilio Vento Canosa, Roger Colten, Andrea Cucina, Francesco Genchi, Claudia Kraan, Francesco Pastina, Michaela Lucci, Marcio Veloz Maggiolo, Beatriz Marcheco-Teruel, Clenis Tavarez Maria, Christian Martínez, Ingeborg París, Michael Pateman, Tanya M. Simms, Carlos Garcia Sivoli, Miguel Vilar, Douglas J. Kennett, William F. Keegan, Alfredo Coppa, Mark Lipson, Ron Pinhasi and David Reich

Cortical response selectivity derives from strength in numbers of synapses pp. 111-114

Benjamin Scholl, Connon I. Thomas, Melissa A. Ryan, Naomi Kamasawa and David Fitzpatrick

Bidirectional perisomatic inhibitory plasticity of a Fos neuronal network pp. 115-121

Ee-Lynn Yap, Noah L. Pettit, Christopher P. Davis, M. Aurel Nagy, David A. Harmin, Emily Golden, Onur Dagliyan, Cindy Lin, Stephanie Rudolph, Nikhil Sharma, Eric C. Griffith, Christopher D. Harvey and Michael E. Greenberg

Restoring metabolism of myeloid cells reverses cognitive decline in ageing pp. 122-128

Paras S. Minhas, Amira Latif-Hernandez, Melanie R. McReynolds, Aarooran S. Durairaj, Qian Wang, Amanda Rubin, Amit U. Joshi, Joy Q. He, Esha Gauba, Ling Liu, Congcong Wang, Miles Linde, Yuki Sugiura, Peter K. Moon, Ravi Majeti, Makoto Suematsu, Daria Mochly-Rosen, Irving L. Weissman, Frank M. Longo, Joshua D. Rabinowitz and Katrin I. Andreasson

Control of osteoblast regeneration by a train of Erk activity waves pp. 129-133

Alessandro De Simone, Maya N. Evanitsky, Luke Hayden, Ben D. Cox, Julia Wang, Valerie A. Tornini, Jianhong Ou, Anna Chao, Kenneth D. Poss and Stefano Di Talia

Underdetection of cases of COVID-19 in France threatens epidemic control pp. 134-139

Giulia Pullano, Laura Di Domenico, Chiara E. Sabbatini, Eugenio Valdano, Clément Turbelin, Marion Debin, Caroline Guerrisi, Charly Kengne-Kuetche, Cécile Souty, Thomas Hanslik, Thierry Blanchon, Pierre-Yves Boëlle, Julie Figoni, Sophie Vaux, Christine Campèse, Sibylle Bernard-Stoecklin and Vittoria Colizza

Age-specific mortality and immunity patterns of SARS-CoV-2 pp. 140-145

Megan O’Driscoll, Gabriel Ribeiro Dos Santos, Lin Wang, Derek A. T. Cummings, Andrew S. Azman, Juliette Paireau, Arnaud Fontanet, Simon Cauchemez and Henrik Salje

Repeated cross-sectional sero-monitoring of SARS-CoV-2 in New York City pp. 146-150

Daniel Stadlbauer, Jessica Tan, Kaijun Jiang, Matthew M. Hernandez, Shelcie Fabre, Fatima Amanat, Catherine Teo, Guha Asthagiri Arunkumar, Meagan McMahon, Christina Capuano, Kathryn Twyman, Jeffrey Jhang, Michael D. Nowak, Viviana Simon, Emilia Mia Sordillo, Harm Bakel and Florian Krammer

Local immune response to food antigens drives meal-induced abdominal pain pp. 151-156

Javier Aguilera-Lizarraga, Morgane V. Florens, Maria Francesca Viola, Piyush Jain, Lisse Decraecker, Iris Appeltans, Maria Cuende-Estevez, Naomi Fabre, Kim Van Beek, Eluisa Perna, Dafne Balemans, Nathalie Stakenborg, Stavroula Theofanous, Goele Bosmans, Stéphanie U. Mondelaers, Gianluca Matteoli, Sales Ibiza Martínez, Cintya Lopez-Lopez, Josue Jaramillo-Polanco, Karel Talavera, Yeranddy A. Alpizar, Thorsten B. Feyerabend, Hans-Reimer Rodewald, Ricard Farre, Frank A. Redegeld, Jiyeon Si, Jeroen Raes, Christine Breynaert, Rik Schrijvers, Cédric Bosteels, Bart N. Lambrecht, Scott D. Boyd, Ramona A. Hoh, Deirdre Cabooter, Maxim Nelis, Patrick Augustijns, Sven Hendrix, Jessica Strid, Raf Bisschops, David E. Reed, Stephen J. Vanner, Alexandre Denadai-Souza, Mira M. Wouters and Guy E. Boeckxstaens

Mechanism of EBV inducing anti-tumour immunity and its therapeutic use pp. 157-162

Il-Kyu Choi, Zhe Wang, Qiang Ke, Min Hong, Dereck W. Paul, Stacey M. Fernandes, Zhuting Hu, Jonathan Stevens, Indira Guleria, Hye-Jung Kim, Harvey Cantor, Kai W. Wucherpfennig, Jennifer R. Brown, Jerome Ritz and Baochun Zhang

Mitochondrial sorting and assembly machinery operates by β-barrel switching pp. 163-169

Hironori Takeda, Akihisa Tsutsumi, Tomohiro Nishizawa, Caroline Lindau, Jon V. Busto, Lena-Sophie Wenz, Lars Ellenrieder, Kenichiro Imai, Sebastian P. Straub, Waltraut Mossmann, Jian Qiu, Yu Yamamori, Kentaro Tomii, Junko Suzuki, Takeshi Murata, Satoshi Ogasawara, Osamu Nureki, Thomas Becker, Nikolaus Pfanner, Nils Wiedemann, Masahide Kikkawa and Toshiya Endo

‘The problem is greater than it’s ever been’: US universities urged to invest in mental-health resources pp. 171-172

Chris Woolston

Zoom fatigue saps grant reviewers’ attention pp. 172-172

Dalmeet Singh Chawla

Five reasons why researchers should learn to love the command line pp. 173-174

Jeffrey M. Perkel

Meet the food pioneer whose meat replacements are rocking the gravy boat pp. 176-176

Jack Leeming