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2000, volume 405, articles 6790

World leaders heap praise on human genome landmark pp. 983-983

Colin Macilwain

The story so far… pp. 983-984

David Dickson

Draft data leave geneticists with a mountain still to climb pp. 984-985

Declan Butler and Paul Smaglik

Call for monitoring plan on German GM crops pp. 986-986

Alison Abbott and Ulrike Hellerer

‘Dolly’ team wins further patents pp. 986-986

Peter Aldhous

Martian gullies tempt NASA to look for water pp. 987-987

Michael Milsteinm

Astronomers fume over night light pp. 987-988

Bill Triplett

Educated US public get more wary of genetic engineering pp. 988-988

Paul Smaglik

Call for more accelerator research pp. 988-988

Quirin Schiermeier

Patent suit on Alzheimer's mouse rejected… pp. 989-989

Rex Dalton

…but controversy over rights lingers on pp. 989-989

Rex Dalton

UK studies ways of paying to join Chile Observatory pp. 990-990

Natasha Loder

Pasteur Institute to abandon departmental structure? pp. 990-990

Declan Butler

Feathers fly in Beijing pp. 992-992

Rex Dalton

Africa needs locally trained soil specialists to improve land use pp. 993-993

Dan H. Yaalon

Did Greeks beat Chinese on blood circulation … pp. 993-993

Tsung O. Cheng

… or was ‘blood as the river of life’ just poetic? pp. 993-993

Plinio Prioreschi

A question of compliance pp. 995-996

Thomas Dormandy

Reactions of a chemical kindred pp. 996-997

Gautam R. Desiraju

Putting science in its place pp. 997-998

David N. Livingstone

Science in culture pp. 998-998

Martin Kemp

The microscope's coat of arms pp. 999-999

Giovanni F. Bignami

Tuberculosis bacteria join UN pp. 1001-1001

Joan Slonczewski

Critical time for fluid dynamos pp. 1003-1004

Andy Jackson

Targeting sheep pp. 1004-1005

Milind Suraokar and Allan Bradley

Misbehaviour in metals pp. 1007-1008

Philip B. Allen

Talking trees tell tales pp. 1008-1009

Rebecca L. Cann

The cosmic origin of deuterium pp. 1009-1010

Francesca Matteucci

Translating activity into plasticity pp. 1011-1012

Aaron DiAntonio

Tradesman's entrance pp. 1012-1012

David Jones

Conditioning and opiate withdrawal pp. 1013-1014

G. Schulteis, S. H. Ahmed, A. C. Morse, G. F. Koob and B. J. Everitt

Enzymatic production of biohydrogen pp. 1014-1015

Jonathan Woodward, Mark Orr, Kimberley Cordray and Elias Greenbaum

Malaria susceptibility and CD36 mutation pp. 1015-1016

Timothy J. Aitman, Lisa D. Cooper, Penny J. Norsworthy, Faisal N. Wahid, Jennefer K. Gray, Brian R. Curtis, Paul M McKeigue, Dominic Kwiatkowski, Brian M. Greenwood, Robert W. Snow, Adrian V Hill and James Scott

Species status of hybridizing oaks pp. 1016-1016

Graham Muir, Colin C. Fleming and Christian Schltterer

Effect of aquaculture on world fish supplies pp. 1017-1024

Rosamond L. Naylor, Rebecca J. Goldburg, Jurgenne H. Primavera, Nils Kautsky, Malcolm C. M. Beveridge, Jason Clay, Carl Folke, Jane Lubchenco, Harold Mooney and Max Troell

Deuterium in the Galactic Centre as a result of recent infall of low-metallicity gas pp. 1025-1027

D. A. Lubowich, Jay M. Pasachoff, Thomas J. Balonek, T. J. Millar, Christy Tremonti, Helen Roberts and Robert P. Galloway

The mean free path for electron conduction in metallic fullerenes pp. 1027-1030

O. Gunnarsson and J. E. Han

Collapse of stiff conjugated polymers with chemical defects into ordered, cylindrical conformations pp. 1030-1033

Dehong Hu, Ji Yu, Kim Wong, Biman Bagchi, Peter J. Rossky and Paul F. Barbara

Dynamic self-assembly of magnetized, millimetre-sized objects rotating at a liquid–air interface pp. 1033-1036

Bartosz A. Grzybowski, Howard A. Stone and George M. Whitesides

Structural basis for the fracture toughness of the shell of the conch Strombus gigas pp. 1036-1040

S. Kamat, X. Su, R. Ballarini and A. H. Heuer

Palaeotemperature reconstruction from noble gases in ground water taking into account equilibration with entrapped air pp. 1040-1044

W. Aeschbach-Hertig, F. Peeters, U. Beyerle and R. Kipfer

The plastic deformation of iron at pressures of the Earth's inner core pp. 1044-1047

H.-R. Wenk, S. Matthies, R. J. Hemley, H.-K. Mao and J. Shu

Ecosystem size determines food-chain length in lakes pp. 1047-1049

David M. Post, Michael L. Pace and Nelson G. Hairston

Cryptophyte algae are robbed of their organelles by the marine ciliate Mesodinium rubrum pp. 1049-1052

Daniel E. Gustafson, Diane K. Stoecker, Matthew D. Johnson, William F. Van Heukelem and Kerri Sneider

Language trees support the express-train sequence of Austronesian expansion pp. 1052-1055

Russell D. Gray and Fiona M. Jordan

Mosaic evolution of brain structure in mammals pp. 1055-1058

Robert A. Barton and Paul H. Harvey

The temporal response of the brain after eating revealed by functional MRI pp. 1058-1062

Yijun Liu, Jia-Hong Gao, Ho-Ling Liu and Peter T. Fox

Postsynaptic translation affects the efficacy and morphology of neuromuscular junctions pp. 1062-1065

Stephan J. Sigrist, Philippe R. Thiel, Dierk F. Reiff, Pascal E. D. Lachance, Paul Lasko and Christoph M. Schuster

Production of gene-targeted sheep by nuclear transfer from cultured somatic cells pp. 1066-1069

K. J. McCreath, J. Howcroft, K. H. S. Campbell, A. Colman, A. E. Schnieke and A.J. Kind

Gigantism in mice lacking suppressor of cytokine signalling-2 pp. 1069-1073

Donald Metcalf, Christopher J. Greenhalgh, Elizabeth Viney, Tracy A. Willson, Robyn Starr, Nicos A. Nicola, Douglas J. Hilton and Warren S. Alexander

Crystal structure of enteropathogenic Escherichia coli intimin–receptor complex pp. 1073-1077

Yu Luo, Elizabeth A. Frey, Richard A. Pfuetzner, A. Louise Creagh, Derek G. Knoechel, Charles A. Haynes, B. Brett Finlay and Natalie C. J. Strynadka

Solid-state NMR determination of the secondary structure of Samia cynthia ricini silk pp. 1077-1079

J. D. van Beek, L. Beaulieu, Hans-Bernd Schäfer, M. Demura, T. Asakura and B. H. Meier

2000, volume 405, articles 6789

German fraud inquiry casts a wider net of suspicion… pp. 871-872

Alison Abbott

…as disillusionment reigns in task force pp. 871-871

Alison Abbott

Oxford epidemiologist wins apology for promotion slur pp. 872-872

Natasha Loder

Hawaii reaches for the stars with astronomy master plan pp. 872-872

Rex Dalton and Alison Abbott

Europe edges closer to an integrated science policy pp. 873-873

Quirin Schiermeier

UK panel calls for more cuts to carbon dioxide emission pp. 873-873

Natasha Loder

Brookhaven collider opens its quest for Big Bang conditions pp. 874-874

Steve Nadis

Shares rebound at scent of draft sequence pp. 875-875

Paul Smaglik

GM food ‘dumped on India as aid’ pp. 875-875

K. S. Jayaraman

A question of trust pp. 878-879

Natasha Loder

Leatherback's survival will depend on an international effort pp. 881-881

Larry Crowder

Biotech pioneers have duties as well as rights pp. 881-881

Bao-Hong Zhang

Don't ignore good work that you have to look for pp. 881-881

Jerry Lanchbury

Database could give children safer medicines pp. 882-882

Piero Impicciatore, Chiara Pandolfini and Maurizio Bonati

Japan may seek embryo cells from overseas pp. 882-882

Tohru Nakanishi

The great Dane of Uraniborg pp. 883-884

Kenneth J. Howell

An alchemist of our times pp. 884-885

Lars-Håkan Svensson

Sex, leaves and rock and roll pp. 885-886

Sandra Knapp

Science in culture pp. 886-886

Martin Kemp

The well-spring pp. 887-887

Lewis Wolpert

In the days of the comet pp. 889-889

John M. Ford

Neural circuits in silicon pp. 891-892

Chris Diorio and Rajesh P. N. Rao

Self-repair in the brain pp. 893-895

Anders Björklund and Olle Lindvall

Shrimp-eat-shrimp pp. 895-895

John Whitfield

Chirality, magnetism and light pp. 895-896

Laurence D. Barron

Reverse gear for Drosophila pp. 896-897

Barry J. Dickson

Electrons in artificial atoms pp. 899-900

Daniel Gammon

A mosquito transformed pp. 900-901

Craig J. Coates

Given a twirl pp. 901-901

Heike Langenberg

Solid explosion pp. 901-901

David Jones

Kent R. Wilson (1937–2000) pp. 902-902

Dudley Herschbach

Antioxidant activity of fresh apples pp. 903-904

Marian V. Eberhardt, Chang Yong Lee and Rui Hai Liu

Whale songs lengthen in response to sonar pp. 903-903

Patrick J. O. Miller, Nicoletta Biassoni, Amy Samuels and Peter L. Tyack

Constraints to growth of boreal forests pp. 904-905

Paul Jarvis and Sune Linder

reply: Constraints to growth of boreal forests pp. 905-905

Eugene A. Vaganov and Malcolm K. Hughes

The genetic legacy of the Quaternary ice ages pp. 907-913

Godfrey Hewitt

Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export pp. 914-919

Vassilis Koronakis, Andrew Sharff, Eva Koronakis, Ben Luisi and Colin Hughes

Optical detection of meteoroidal impacts on the Moon pp. 921-923

J. L. Ortiz, P. V. Sada, L. R. Bellot Rubio, F. J. Aceituno, J. Aceituno, P. J. Gutiérrez and U. Thiele

Hidden symmetries in the energy levels of excitonic ‘artificial atoms’ pp. 923-926

M. Bayer, O. Stern, P. Hawrylak, S. Fafard and A. Forchel

Optical emission from a charge-tunable quantum ring pp. 926-929

R. J. Warburton, C. Schäflein, D. Haft, F. Bickel, A. Lorke, K. Karrai, J. M. Garcia, W. Schoenfeld and P. M. Petroff

Gigantic optical nonlinearity in one-dimensional Mott–Hubbard insulators pp. 929-932

H. Kishida, H. Matsuzaki, H. Okamoto, T. Manabe, M. Yamashita, Y. Taguchi and Y. Tokura

Enantioselective magnetochiral photochemistry pp. 932-935

G. L. J. A. Rikken and E. Raupach

Reduced North Atlantic Deep Water flux to the glacial Southern Ocean inferred from neodymium isotope ratios pp. 935-938

Randye L. Rutberg, Sidney R. Hemming and Steven L. Goldstein

Mapping the Hawaiian plume conduit with converted seismic waves pp. 938-941

X. Li, R. Kind, K. Priestley, S. V. Sobolev, F. Tilmann, X. Yuan and M. Weber

A pug-nosed crocodyliform from the Late Cretaceous of Madagascar pp. 941-944

Gregory A. Buckley, Christopher A. Brochu, David W. Krause and Diego Pol

Diversity and endemism of the benthic seamount fauna in the southwest Pacific pp. 944-947

Bertrand Richer de Forges, J. Anthony Koslow and G. C. B. Poore

Digital selection and analogue amplification coexist in a cortex-inspired silicon circuit pp. 947-951

Richard H. R. Hahnloser, Rahul Sarpeshkar, Misha A. Mahowald, Rodney J. Douglas and H. Sebastian Seung

Induction of neurogenesis in the neocortex of adult mice pp. 951-955

Sanjay S. Magavi, Blair R. Leavitt and Jeffrey D. Macklis

Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity pp. 955-959

Hey-Kyoung Lee, Michaela Barbarosie, Kimihiko Kameyama, Mark F. Bear and Richard L. Huganir

Stable germline transformation of the malaria mosquito Anopheles stephensi pp. 959-962

Flaminia Catteruccia, Tony Nolan, Thanasis G. Loukeris, Claudia Blass, Charalambos Savakis, Fotis C. Kafatos and Andrea Crisanti

A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis pp. 962-966

C. Kendall Stover, Paul Warrener, Donald R. VanDevanter, David R. Sherman, Taraq M. Arain, Michael H. Langhorne, Scott W. Anderson, J. Andrew Towell, Ying Yuan, David N. McMurray, Barry N. Kreiswirth, Clifton E. Barry and William R. Baker

Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1 pp. 966-970

Stacey S. Huppert, Anh Le, Eric H. Schroeter, Jeffrey S. Mumm, Meera T. Saxena, Laurie A. Milner and Raphael Kopan

An extracellular activator of the Drosophila JAK/STAT pathway is a sex-determination signal element pp. 970-973

Louise Sefton, John R. Timmer, Yan Zhang, Florence Béranger and Thomas W. Cline

Compromised HOXA5 function can limit p53 expression in human breast tumours pp. 974-978

Venu Raman, Shelby A. Martensen, David Reisman, Ella Evron, Ward F. Odenwald, Elizabeth Jaffee, Jeffrey Marks and Saraswati Sukumar

2000, volume 405, articles 6788

Relations thaw between genome rivals as finish line draws near pp. 721-721

Paul Smaglik

Canada unifies medical research community pp. 722-722

David Spurgeon

Miniature antennas will eavesdrop on the Universe pp. 722-722

Steve Nadis

European centres rebuffed in infrastructure funding bid pp. 723-723

Quirin Schiermeier

Spanish postgrads push for better employment rights pp. 723-723

Xavier Bosch

NIH panel may increase gene-trial scrutiny… pp. 724-724

Paul Smaglik

…as Europe's ‘excessive secrecy’ is deplored pp. 724-724

Declan Butler

UK researchers call for limits on animal experiment ‘red tape’ pp. 725-725

Natasha Loder

US climate report underlines local impacts of warming pp. 725-725

Paul Smaglik

Los Alamos ‘loses’ key weapons data pp. 725-725

Rex Dalton

One for all — and all for one pp. 728-728

Alison Abbott

Nanotech thinks big pp. 730-732

Colin Macilwain

‘Underachieving’ centre has not only struck gold but made good use of it pp. 733-733

Helmut Blöcker

Jumping the gun on mouse gene expression pp. 733-733

Magdalena Zernicka-Goetz

Setbacks don't dampen the energy of US physics pp. 733-733

Andrew M. Sessler

How the GM industry writes its own rules pp. 733-733

Philip L. Bereano

W. D. Hamilton memorial pp. 733-733

Richard Dawkins

Aping human societies pp. 735-736

Adrienne Zihlman

When Galileo turned to verse pp. 735-735

Dava Sobel

A helping hand on elementary matters pp. 736-737

P. W. Anderson

Portrait of an élite world pp. 737-738

John Gascoigne

An unholy alliance pp. 739-739

Ute Deichmann

Another green world pp. 741-741

Henry Wessells

Moon, tides and climate pp. 743-744

Carl Wunsch

Greater lifetime expectations pp. 744-745

Shiro Horiuchi

Smart polymer solutions pp. 745-747

Jacob Klein

Nervous engineering pp. 747-748

Melitta Schachner

Curves and numbers pp. 748-749

Ivar Ekeland

GTPase traffic control pp. 749-751

Channing J. Der and William E. Balch

Fungal get-together pp. 751-751

Nicholas P. Money

Eye contact pp. 752-752

David Jones

Survival of the Irish elk into the Holocene pp. 753-754

Silvia Gonzalez, Andrew C. Kitchener and Adrian M. Lister

Control of free calcium in plant cell nuclei pp. 754-755

Nicolas Pauly, Marc R. Knight, Patrice Thuleau, Arnold H. van der Luit, Marc Moreau, Anthony J. Trewavas, Raoul Ranjeva and Christian Mazars

Risky immortalization by telomerase pp. 755-756

Jing Wang, Gregory J. Hannon and David H. Beach

Do cockroaches ‘know’ about fluid dynamics? pp. 756-756

D. Rinberg and H. Davidowitz

The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signalling pp. 757-763

Michael Oelgeschläger, Juan Larraín, Douglas Geissert and Eddy M. De Robertis

Kondo effect in an integer-spin quantum dot pp. 764-767

S. Sasaki, S. De Franceschi, J. M. Elzerman, W. G. van der Wiel, M. Eto, S. Tarucha and L. P. Kouwenhoven

Direct observation of the alignment of ferromagnetic spins by antiferromagnetic spins pp. 767-769

F. Nolting, A. Scholl, J. Stöhr, J. W. Seo, J. Fompeyrine, H. Siegwart, J.-P. Locquet, S. Anders, J. Lüning, E. E. Fullerton, M. F. Toney, M. R. Scheinfein and H. A. Padmore

Reversible electromechanical characteristics of carbon nanotubes underlocal-probe manipulation pp. 769-772

Thomas W. Tombler, Chongwu Zhou, Leo Alexseyev, Jing Kong, Hongjie Dai, Lei Liu, C. S. Jayanthi, Meijie Tang and Shi-Yu Wu

Controlling droplet deposition with polymer additives pp. 772-775

Vance Bergeron, Daniel Bonn, Jean Yves Martin and Louis Vovelle

Significant dissipation of tidal energy in the deep ocean inferred from satellite altimeter data pp. 775-778

G. D. Egbert and R. D. Ray

A larger pool of ozone-forming carbon compounds in urban atmospheres pp. 778-781

Alastair C. Lewis, Nicola Carslaw, Philip J. Marriott, Russel M. Kinghorn, Paul Morrison, Andrew L. Lee, Keith D. Bartle and Michael J. Pilling

Re–Os isotopic evidence for a lower crustal origin of massif-type anorthosites pp. 781-784

Henrik Schiellerup, David D. Lambert, Tore Prestvik, Brian Robins, Jannene S. McBride and Rune B. Larsen

Unrelated helpers in a social insect pp. 784-787

David C. Queller, Francesca Zacchi, Rita Cervo, Stefano Turillazzi, Michael T. Henshaw, Lorenzo A. Santorelli and Joan E. Strassmann

Female feral fowl eject sperm of subdominant males pp. 787-789

T. Pizzari and T. R. Birkhead

A universal pattern of mortality decline in the G7 countries pp. 789-792

Shripad Tuljapurkar, Nan Li and Carl Boe

Ultrasensitive pheromone detection by mammalian vomeronasal neurons pp. 792-796

Trese Leinders-Zufall, Andrew P. Lane, Adam C. Puche, Weidong Ma, Milos V. Novotny, Michael T. Shipley and Frank Zufall

Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia pp. 797-800

N. M. Page, R. J. Woods, S. M. Gardiner, K. Lomthaisong, R. T. Gladwell, D. J. Butlin, I. T. Manyonda and P. J. Lowry

The γ-subunit of the coatomer complex binds Cdc42 to mediate transformation pp. 800-804

Wen Jin Wu, Jon W. Erickson, Rui Lin and Richard A. Cerione

Two-headed binding of a processive myosin to F-actin pp. 804-807

Matthew L. Walker, Stan A. Burgess, James R. Sellers, Fei Wang, John A. Hammer, John Trinick and Peter J. Knight

The lyase activity of the DNA repair protein β-polymerase protects from DNA-damage-induced cytotoxicity pp. 807-810

Robert W. Sobol, Rajendra Prasad, Andrea Evenski, Audrey Baker, Xiao-Ping Yang, Julie K. Horton and Samuel H. Wilson

Observations of light-induced structural changes of retinal within rhodopsin pp. 810-813

Gerhard Gröbner, Ian J. Burnett, Clemens Glaubitz, Gregory Choi, A. James Mason and Anthony Watts

Atomically defined mechanism for proton transfer to a buried redox centre in a protein pp. 814-817

Kaisheng Chen, Judy Hirst, Raul Camba, Christopher A. Bonagura, C. David Stout, Barbara. K. Burgess and Fraser A. Armstrong

Exploring genome space pp. 820-822

Ognjenka Goga Vukmirovic and Shirley M. Tilghman

Protein function in the post-genomic era pp. 823-826

David Eisenberg, Edward M. Marcotte, Ioannis Xenarios and Todd O. Yeates

Genomics, gene expression and DNA arrays pp. 827-836

David J. Lockhart and Elizabeth A. Winzeler

Proteomics to study genes and genomes pp. 837-846

Akhilesh Pandey and Matthias Mann

Searching for genetic determinants in the new millennium pp. 847-856

Neil J. Risch

Pharmacogenetics and the practice of medicine pp. 857-865

Allen D. Roses

2000, volume 405, articles 6787

New Russian science head named pp. 601-601

Carl Levitin

Biologists challenge sequencers on parasite genome publication pp. 601-602

Colin Macilwain

Drive for more genomes threatens mouse sequence pp. 602-603

Alison Abbott

Software spend boosts Israeli R&D pp. 603-603

Haim Watzman

Internet gateway planned for neuroinformatics data pp. 603-603

Paul Smaglik

Spain in quandary over French synchrotron pp. 604-604

Xavier Bosch

Immigrants help offset Canada's brain-drain crisis pp. 604-604

David Spurgeon

A slot in the dock predicted for the chemical industry pp. 605-605

Natasha Loder

Roche brings down curtain on Swiss immunology lab pp. 605-605

Alison Abbott

US decides close tabs must be kept on xenotransplants… pp. 606-607

Declan Butler

… and sets up a body to oversee trials pp. 607-607

Paul Smaglik

Cloning's owners go to war pp. 610-612

Peter Aldhous

Regulation, not private enterprise, is the key to a healthy environment pp. 613-613

George M. Woodwell

England and US corner the journal market pp. 613-613

A. A. Waheed

Celera's role in opening up new frontiers pp. 613-613

Ken Calvert

Climate change in perspective pp. 615-615

Hans von Storch and Nico Stehr

Skull and cross words pp. 617-617

Simon Conway Morris

The quantum jungle revisited pp. 618-618

Anton Zeilinger

The Wonderland of primordial life pp. 619-620

John Godfrey

Hands-on taxonomy pp. 619-619

Henry Disney

Science in culture pp. 620-620

Alison Abbott

Show them how it's really done pp. 621-621

Nancy J. Rothwell

New ice age, or just cold feet? pp. 623-623

Norman Spinrad

The realms of Archaean life pp. 625-626

Euan Nisbet

Semiconductors meet biology pp. 626-627

Chad A. Mirkin and T. Andrew Taton

Closing in on γ-secretase pp. 627-628

Bart De Strooper

Half-matter, half-light amplifier pp. 629-630

Yoshihisa Yamamoto

It takes two electrons to tango pp. 631-633

Keith Burnett

Gripping feat pp. 631-631

Henry Gee

Pumping ions pp. 633-634

David H. MacLennan and N. Michael Green

Pumping a vacuum pp. 634-634

David Jones

Recombinant erythropoietin in urine pp. 635-635

Françoise Lasne and Jacques de Ceaurriz

Parabasalian flagellates are ancient eukaryotes pp. 635-637

Patrick J. Keeling and Jeffrey D. Palmer

Tectonics and water on Europa pp. 637-637

Eric J. Gaidos and Francis Nimmo

Scalar turbulence pp. 639-646

Boris I. Shraiman and Eric D. Siggia

Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 Å resolution pp. 647-655

Chikashi Toyoshima, Masayoshi Nakasako, Hiromi Nomura and Haruo Ogawa

Newly synthesized lithium in the interstellar medium pp. 656-658

D. C. Knauth, S. R. Federman, David L. Lambert and P. Crane

Correlated electron emission in multiphoton double ionization pp. 658-661

Th. Weber, H. Giessen, M. Weckenbrock, G. Urbasch, A. Staudte, L. Spielberger, O. Jagutzki, V. Mergel, M. Vollmer and R. Dörner

Improving the performance of doped π-conjugated polymers for use in organic light-emitting diodes pp. 661-665

Markus Gross, David C. Müller, Heinz-Georg Nothofer, Ulrich Scherf, Dieter Neher, Christoph Bräuchle and Klaus Meerholz

Selection of peptides with semiconductor binding specificity for directed nanocrystal assembly pp. 665-668

Sandra R. Whaley, D. S. English, Evelyn L. Hu, Paul F. Barbara and Angela M. Belcher

Reduced growth of Alaskan white spruce in the twentieth century from temperature-induced drought stress pp. 668-673

Valerie A. Barber, Glenn Patrick Juday and Bruce P. Finney

Isotopic evidence for Late Cretaceous plume–ridge interaction at the Hawaiian hotspot pp. 673-676

Randall A. Keller, Martin R. Fisk and William M. White

Filamentous microfossils in a 3,235-million-year-old volcanogenic massive sulphide deposit pp. 676-679

Birger Rasmussen

Parasite adaptation to locally common host genotypes pp. 679-681

Curtis M. Lively and Mark F. Dybdahl

Adhesive force of a single gecko foot-hair pp. 681-685

Kellar Autumn, Yiching A. Liang, S. Tonia Hsieh, Wolfgang Zesch, Wai Pang Chan, Thomas W. Kenny, Ronald Fearing and Robert J. Full

Neural synchrony correlates with surface segregation rules pp. 685-689

Miguel Castelo-Branco, Rainer Goebel, Sergio Neuenschwander and Wolf Singer

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1 pp. 689-694

Yue-Ming Li, Min Xu, Ming-Tain Lai, Qian Huang, José L. Castro, Jillian DiMuzio-Mower, Timothy Harrison, Colin Lellis, Alan Nadin, Joseph G. Neduvelil, R. Bruce Register, Mohinder K. Sardana, Mark S. Shearman, Adrian L. Smith, Xiao-Ping Shi, Kuo-Chang Yin, Jules A. Shafer and Stephen J. Gardell

α-Haemolysin of uropathogenic E. coli induces Ca2+ oscillations in renal epithelial cells pp. 694-697

Per Uhlén, Åsa Laestadius, Timo Jahnukainen, Tomas Söderblom, Fredrik Bäckhed, Gianni Celsi, Hjalmar Brismar, Staffan Normark, Anita Aperia and Agneta Richter-Dahlfors

Frequent chromosomal translocations induced by DNA double-strand breaks pp. 697-700

Christine Richardson and Maria Jasin

Redundant roles for the TFIID and SAGA complexes in global transcription pp. 701-704

Tong Ihn Lee, Helen C. Causton, Frank C. P. Holstege, Wu-Cheng Shen, Nancy Hannett, Ezra G. Jennings, Fred Winston, Michael R. Green and Richard A. Young

Effects of mechanical forces on maintenance and adaptation of form in trabecular bone pp. 704-706

Rik Huiskes, Ronald Ruimerman, G. Harry van Lenthe and Jan D. Janssen

Biological sensing of small field differences by magnetically sensitive chemical reactions pp. 707-709

James C. Weaver, Timothy E. Vaughan and R. Dean Astumian

US science shocked by revelations of sexual discrimination pp. 713-714

Natasha Loder

Making moves to redress the gender imbalance pp. 715-716

Helen Gavaghan

New UK legislation aids fight against discrimination pp. 716-717

Helen Gavaghan

US minorities stake their claim in science and engineering pp. 717-718

Potter Wickware

Canadian aborigines get overlooked pp. 717-717

Potter Wickware

Access to education provides a way out pp. 718-718

Potter Wickware

2000, volume 405, articles 6786

…as amphibians come under study pp. 495-496

Rex Dalton

Researchers take US government to court over threat to turtles… pp. 495-495

Natasha Loder

Green light for plans to sell off US helium reserve pp. 496-496

Colin Macilwain

UK labs impeded by old equipment pp. 496-496

Natasha Loder

Clinical trials end at gene-therapy institute… pp. 497-497

Paul Smaglik

…as Harvard keeps its ethics guidelines pp. 497-497

Steve Nadis

France plans marine research port at Brest pp. 498-498

Declan Butler

Transmutation of nuclear waste branded ‘Trojan horse’ pp. 498-498

Colin Macilwain

Germany edges towards stem-cell accord pp. 499-499

Quirin Schiermeier

Survey nets volcanic prize pp. 499-499

Peter Pockley

French scientists turn to journals in English pp. 500-500

Declan Butler

World's academies seek a sustainable future pp. 501-501

Robert Triendl

Requiem for an observatory pp. 504-506

Henry Bortman

Impact factors aren't relevant to taxonomy pp. 507-508

Frank-Thorsten Krell

To conserve rainforest, we have to help local people live sustainably pp. 507-507

S. Jennings, N. D. Brown, T. C. Whitmore, J. N. M. Silva, J. do C. A. Lopes and A. M. V. Baima

We have moral authority to apologize for the past pp. 508-508

Damian Grace and John Carmody

Offside researchers score an own goal pp. 508-508

Winfried S. Peters, Bernd Herkner, Alex Webb and Julian Hibberd

Let Armenia show why it's the place for Sesame pp. 508-508

J. S. Hovnanian

Giving Arabs credit for Persian works (again) pp. 508-508

Payman Arabshahi

Time for voices to be raised pp. 509-509

Derek Burke

The house that Jim built pp. 511-512

Sydney Brenner

Mozart, McCartney and sexual selection pp. 512-513

Margaret A. Boden

Statistical detective pp. 513-513

Ian Hacking

Making sense of a small world pp. 514-514

Maxine Clarke

A double-edged sword pp. 515-515

Diane Paul

Catching crumbs from the table pp. 517-517

Ted Chiang

Pax Argentinica pp. 519-520

David C. Queller

Neutralizing noise in gene networks pp. 520-521

Timothy S. Gardner and James J. Collins

Hard knock for thermodynamics pp. 521-523

Salvatore Torquato

Learning how the brain learns pp. 523-525

Eilon Vaadia

A watched pot boils quicker pp. 525-526

Peter W. Milonni

Case of the bends pp. 525-525

Tim Lincoln

The footprint of a killer pp. 527-528

Klas Kärre and Gunter Schneider

Air currents pp. 528-528

David Jones

Pacific leatherback turtles face extinction pp. 529-530

James R. Spotila, Richard D. Reina, Anthony C. Steyermark, Pamela T. Plotkin and Frank V. Paladino

Fossil record of mass moth migration pp. 530-531

Jes Rust

Presenilin-1 mutations in Alzheimer's disease pp. 531-532

C. Russo, G. Schettini, T. C. Saido, C. Hulette, C. Lippa, L. Lannfelt, B. Ghetti, P. Gambetti, M. Tabaton and J. K. Teller

A massive cool dust torus around η Carinae? pp. 532-532

Kris Davidson and Nathan Smith

Inferring the statistical interpretation of quantum mechanics from the classical limit pp. 533-536

Kurt Gottfried

Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand pp. 537-543

Jeffrey C. Boyington, Shawn A. Motyka, Peter Schuck, Andrew G. Brooks and Peter D. Sun

Rossby waves on the Sun as revealed by solar ‘hills’ pp. 544-546

J. R. Kuhn, J. D. Armstrong, R. I. Bush and P. Scherrer

Acceleration of quantum decay processes by frequent observations pp. 546-550

A. G. Kofman and G. Kurizki

Absence of thermodynamic phase transition in a model glass former pp. 550-551

Ludger Santen and Werner Krauth

Dynamics of the silicon (111) surface phase transition pp. 552-554

J. B. Hannon, H. Hibino, N. C. Bartelt, B. S. Swartzentruber, T. Ogino and G. L. Kellogg

Old radiocarbon ages in the southwest Pacific Ocean during the last glacial period and deglaciation pp. 555-559

Elisabeth L. Sikes, Catherine R. Samson, Thomas P. Guilderson and William R. Howard

Multiple seismic discontinuities near the base of the transition zone in the Earth's mantle pp. 559-562

N. A. Simmons and H. Gurrola

Are lemmings prey or predators? pp. 562-565

P. Turchin, L. Oksanen, P. Ekerholm, T. Oksanen and H. Henttonen

Highly fecund mothers sacrifice offspring survival to maximize fitness pp. 565-567

Sigurd Einum and Ian A. Fleming

Cortical ensemble activity increasingly predicts behaviour outcomes during learning of a motor task pp. 567-571

Mark Laubach, Johan Wessberg and Miguel A. L. Nicolelis

An electroneutral sodium/bicarbonate cotransporter NBCn1 and associated sodium channel pp. 571-575

Inyeong Choi, Christian Aalkjaer, Emile L. Boulpaep and Walter F. Boron

Cyclin D control of growth rate in plants pp. 575-579

Claire E. Cockcroft, Bart G. W. den Boer, J. M. Sandra Healy and James A. H. Murray

Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway pp. 579-583

Glenn C. Turner, Fangyong Du and Alexander Varshavsky

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule pp. 583-586

Craig H. Bassing, Frederick W. Alt, Maureen M. Hughes, Margaux D'Auteuil, Tara D. Wehrly, Barbara B. Woodman, Frank Gärtner, J. Michael White, Laurie Davidson and Barry P. Sleckman

Intraprotein radical transfer during photoactivation of DNA photolyase pp. 586-590

Corinne Aubert, Marten H. Vos, Paul Mathis, André P. M. Eker and Klaus Brettel

Engineering stability in gene networks by autoregulation pp. 590-593

Attila Becskei and Luis Serrano

US Congress encouraged to lay out the welcome mat for skilled foreigners pp. 597-598

Diane Gershon

Germany faces up to its labour shortage pp. 597-597

Diane Gershon

The economic impact of Silicon Valley's immigrant entrepreneurs pp. 598-598

Diane Gershon

2000, volume 405, articles 6785

US astronomers draw up their wish list for a decade of funding pp. 381-382

Tony Reichhardt

France sets up élite Internet school pp. 381-381

Heather McCabe

Britain asks to join European Southern Observatory pp. 382-383

David Dickson and Alison Abbott

Mathematicians chase the seven million-dollar proofs pp. 383-383

David Dickson

BioMed Central boosted by editorial board pp. 384-384

Declan Butler

Russian PM supports science pp. 384-384

Carl Levitin

Congress wakes up to climate change pp. 385-385

Colin Macilwain

French unions upset by plans for physiology centre pp. 385-385

Heather McCabe

Bacterial AIDS vaccine ready for testing pp. 386-386

Paul Smaglik

Tax blow leaves Australian science reeling pp. 387-387

Peter Pockley

Changing of the guard pp. 389-389

Trisha Gura

Deep thoughts pp. 390-392

Rex Dalton

… following Africa's lead in setting priorities pp. 393-394

Gustavo A. B. da Fonseca, Andrew Balmford, Colin Bibby, Luigi Boitani, Fabio Corsi, Thomas Brooks, Claude Gascon, Silvio Olivieri, Russell A. Mittermeier, Neil Burgess, Eric Dinerstein, David Olson, Lee Hannah, Jon Lovett, David Moyer, Carsten Rahbek, Simon Stuart and Paul Williams

It's time to work together and stop duplicating conservation efforts … pp. 393-393

G. M. Mace, A. Balmford, L. Boitani, G. Cowlishaw, A. P. Dobson, D. P. Faith, K. J. Gaston, C. J. Humphries, R. I. Vane-Wright, P. H. Williams, J. H. Lawton, C. R. Margules, R. M. May, A. O. Nicholls, H. P. Possingham, C. Rahbek and A. S. van Jaarsveld

Community groups could show Unesco the way pp. 394-394

Gérard Toulouse

It won't come to the Crunch pp. 395-396

William H. Press

Stopping the tectonic conveyor belt pp. 396-396

David Bercovici

A Gouldian valediction, almost pp. 397-397

Henry Gee

The many faces of science pp. 397-398

Lisa Jardine

Many paths to enlightenment pp. 399-399

Susantha Goonatilake

Brochure pp. 401-401

Joe Haldeman

Loophole for snowball Earth pp. 403-404

Bruce Runnegar

New link in a web of human genes pp. 404-405

Jean Y. J. Wang

Three's a crowd pp. 405-407

Alan P. Boss

Silence across the border pp. 408-409

Wolf Reik and Adele Murrell

Inner core takes another turn pp. 411-412

Henri-Claude Nataf

Carbon fixation pp. 412-412

Jim Gillon

The power of design pp. 412-413

Mark Newman

Self-regulating synapses pp. 413-414

Christine R. Rose and Arthur Konnerth

Opal appeal pp. 414-414

Karen Southwell

The bases for Cockayne syndrome pp. 415-415

Philip C. Hanawalt

The depths of madness pp. 416-416

David Jones

Wireless capsule endoscopy pp. 417-417

Gavriel Iddan, Gavriel Meron, Arkady Glukhovsky and Paul Swain

Non-thermal heat-shock response to microwaves pp. 417-418

David de Pomerai, Clare Daniells, Helen David, Joanna Allan, Ian Duce, Mohammed Mutwakil, David Thomas, Phillip Sewell, John Tattersall, Don Jones and Peter Candido

Proton-powered turbine of a plant motor pp. 418-419

Holger Seelert, Ansgar Poetsch, Norbert A. Dencher, Andreas Engel, Henning Stahlberg and Daniel J. Müller

Roles of PPARs in health and disease pp. 421-424

Sander Kersten, Béatrice Desvergne and Walter Wahli

Neoproterozoic ‘snowball Earth’ simulations with a coupled climate/ice-sheet model pp. 425-429

William T. Hyde, Thomas J. Crowley, Steven K. Baum and W. Richard Peltier

A triplet of differently shaped spin-zero states in the atomic nucleus 186Pb pp. 430-433

A. N. Andreyev, M. Huyse, P. Van Duppen, L. Weissman, D. Ackermann, J. Gerl, F. P. Hessberger, S. Hofmann, A. Kleinböhl, G. Münzenberg, S. Reshitko, C. Schlegel, H. Schaffner, P. Cagarda, M. Matos, S. Saro, A. Keenan, C. Moore, C. D. O'Leary, R. D. Page, Mark Taylor, H. Kettunen, M. Leino, A. Lavrentiev, R. Wyss and K. Heyde

Microdomain patterns from directional eutectic solidification and epitaxy pp. 433-437

Claudio De Rosa, Cheolmin Park, Edwin L. Thomas and Bernard Lotz

Large-scale synthesis of a silicon photonic crystal with a complete three-dimensional bandgap near 1.5 micrometres pp. 437-440

Alvaro Blanco, Emmanuel Chomski, Serguei Grabtchak, Marta Ibisate, Sajeev John, Stephen W. Leonard, Cefe Lopez, Francisco Meseguer, Hernan Miguez, Jessica P. Mondia, Geoffrey A. Ozin, Ovidiu Toader and Henry M. van Driel

Deep convective clouds with sustained supercooled liquid water down to -37.5 °C pp. 440-442

Daniel Rosenfeld and William L. Woodley

Past temperature and δ18O of surface ocean waters inferred from foraminiferal Mg/Ca ratios pp. 442-445

H. Elderfield and G. Ganssen

Slow differential rotation of the Earth's inner core indicated by temporal changes in scattering pp. 445-448

John E. Vidale, Doug A. Dodge and Paul S. Earle

Invasion sequence affects predator–prey dynamics in a multi-species interaction pp. 448-450

Steven M. Sait, Wei-Chung Liu, David J. Thompson, H. Charles J. Godfray and Michael Begon

Chromosomal evolution in Saccharomyces pp. 451-454

G. Fischer, S. A. James, I. N. Roberts, S. G. Oliver and E. J. Louis

Synaptic activity at calcium-permeable AMPA receptors induces a switch in receptor subtype pp. 454-458

Si-Qiong June Liu and Stuart G. Cull-Candy

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin pp. 458-462

Lyudmila V. Borovikova, Svetlana Ivanova, Minghuang Zhang, Huan Yang, Galina I. Botchkina, Linda R. Watkins, Haichao Wang, Naji Abumrad, John W. Eaton and Kevin J. Tracey

Targeted destabilization of HY5 during light-regulated development of Arabidopsis pp. 462-466

Mark T. Osterlund, Christian S. Hardtke, Ning Wei and Xing Wang Deng

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products pp. 473-477

Song Zhao, Yi-Chinn Weng, Shyng-Shiou F. Yuan, Yi-Tzu Lin, Hao-Chi Hsu, Suh-Chin J. Lin, Elvira Gerbino, Mei-hua Song, Malgorzata Z. Zdzienicka, Richard A. Gatti, Jerry W. Shay, Yael Ziv, Yosef Shiloh and Eva Y.-H. P. Lee

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response pp. 477-482

Xiaohua Wu, Velvizhi Ranganathan, David S. Weisman, Walter F. Heine, David N. Ciccone, Ted B. O'Neill, Kindra E. Crick, Kerry A. Pierce, William S. Lane, Gary Rathbun, David M. Livingston and David T. Weaver

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene pp. 482-485

Adam C. Bell and Gary Felsenfeld

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus pp. 486-489

Amy T. Hark, Christopher J. Schoenherr, David J. Katz, Robert S. Ingram, John M. Levorse and Shirley M. Tilghman

2000, volume 405, articles 6784

Europe agrees to boost Internet networks used by researchers pp. 261-262

Declan Butler

Congo war increases threat to bonobo research pp. 262-262

Asako Saegusa

NIH takes charge of chimps infected in experiments pp. 262-262

Paul Smaglik

Cheaper AIDS drugs due for Third World… pp. 263-263

Phyllida Brown

…but South Africa voices reservations pp. 263-263

Michael Cherry

Geneticist from Baylor named as new head of UK's Sanger Centre pp. 264-264

David Dickson

Los Alamos labs are safe from fire pp. 264-264

Rex Dalton

Researchers take a gamble on the human genome pp. 264-264

Paul Smaglik

Gene bank to offer family album of mammals pp. 265-265

Natasha Loder

Japan calls for open access to human genome data pp. 265-265

Robert Triendl

Greens persuade Europe to revoke patent on neem tree… pp. 266-267

Ulrike Hellerer and K. S. Jarayaman

…as India pushes ahead with plant database pp. 267-267

K. S. Jarayaman

Reservoirs dog AIDS therapy pp. 270-272

Paul Smaglik

AIDS dissidents aren't victims — but the people their ideas kill will be pp. 273-273

Edward Rybicki, Anna-Lise Williamson and Lynn Morris

Bureaucracy strangles Latin American research pp. 273-273

Julio E. Pérez and Abul K. Bashirullah

Emblem of a golden era pp. 275-276

W. F. Bynum

Witness after the event pp. 276-277

Mark Benecke

Of viruses and men pp. 277-278

Robin A. Weiss

Science in culture pp. 278-278

Martin Kemp

More is less pp. 279-279

Terence Kealey

Consequences pp. 281-281

Poul Anderson

Recounting a genetic story pp. 283-284

Roger H. Reeves

The comet no one saw pp. 285-287

Michael F. A'Hearn

Checkpoint for invasion pp. 287-288

Lance A. Liotta and Timothy Clair

Nutrients in the glacial balance pp. 288-291

Peggy Delaney

Bioluminescence illuminated pp. 291-292

Franklyn G. Prendergast

Centrioles go for a stroll pp. 292-292

Manfred Schliwa

Plastic sandwiches à la carte pp. 293-294

Michael D. Ward

Drink without drinking pp. 294-294

David Jones

Guiding the swing in golf putting pp. 295-296

C. M. Craig, D. Delay, M. A. Grealy and D. N. Lee

Evolution of lifespan in C. elegans pp. 296-297

David W. Walker, Gawain McColl, Nicole L. Jenkins, Jennifer Harris and Gordon J. Lithgow

How cicadas interpret acoustic signals pp. 297-298

P. J. Fonseca, D. Münch and R. M. Hennig

Transfection of cells by immunoporation pp. 298-298

Lale Bildirici, Patricia Smith, Christos Tzavelas, Elina Horefti and David Rickwood

Lateral gene transfer and the nature of bacterial innovation pp. 299-304

Howard Ochman, Jeffrey G. Lawrence and Eduardo A. Groisman

Oceanic Cd/P ratio and nutrient utilization in the glacial Southern Ocean pp. 305-310

H. Elderfield and R. E. M. Rickaby

The DNA sequence of human chromosome 21 pp. 311-319

M. Hattori, A. Fujiyama, T. D. Taylor, H. Watanabe, T. Yada, H.-S. Park, A. Toyoda, K. Ishii, Y. Totoki, D.-K. Choi, E. Soeda, M. Ohki, T. Takagi, Y. Sakaki, S. Taudien, K. Blechschmidt, A. Polley, U. Menzel, J. Delabar, K. Kumpf, R. Lehmann, D. Patterson, K. Reichwald, A. Rump, M. Schillhabel, A. Schudy, W. Zimmermann, A. Rosenthal, J. Kudoh, K. Shibuya, K. Kawasaki, S. Asakawa, A. Shintani, T. Sasaki, K. Nagamine, S. Mitsuyama, S. E. Antonarakis, S. Minoshima, N. Shimizu, G. Nordsiek, K. Hornischer, P. Brandt, M. Scharfe, O. Schön, A. Desario, J. Reichelt, G. Kauer, H. Blöcker, J. Ramser, A. Beck, S. Klages, S. Hennig, L. Riesselmann, E. Dagand, T. Haaf, S. Wehrmeyer, K. Borzym, K. Gardiner, D. Nizetic, F. Francis, H. Lehrach, R. Reinhardt and M.-L. Yaspo

Discovery of a comet by its Lyman-α emission pp. 321-322

J. Teemu T. Mäkinen, Jean-Loup Bertaux, Harri Laakso, Tuija Pulkkinen, Tuula Summanen, Erkki Kyrölä, Walter Schmidt, Eric Quémerais and Rosine Lallement

Thermally fluctuating superconductors in two dimensions pp. 322-325

Subir Sachdev and Oleg A. Starykh

Optical microscopy using a single-molecule light source pp. 325-328

J. Michaelis, C. Hettich, J. Mlynek and V. Sandoghdar

Intercalation of alkylamines into an organic polymer crystal pp. 328-330

Akikazu Matsumoto, Toru Odani, Kazuki Sada, Mikiji Miyata and Kohji Tashiro

Constraining the atmospheric N2O budget from intramolecular site preference in N2O isotopomers pp. 330-334

Naohiro Yoshida and Sakae Toyoda

Simulated influences of Lake Agassiz on the climate of central North America 11,000 years ago pp. 334-337

S. W. Hostetler, P. J. Bartlein, P. U. Clark, E. E. Small and A. M. Solomon

Mesozoic plate-motion history below the northeast Pacific Ocean from seismic images of the subducted Farallon slab pp. 337-340

Hans-Peter Bunge and Stephen P. Grand

Functional diversity governs ecosystem response to nutrient enrichment pp. 340-344

Florence D. Hulot, Gérard Lacroix, Françoise Lescher-Moutoué and Michel Loreau

Adaptive plasticity in mate preference linked to differences in reproductive effort pp. 344-347

Anna Qvarnström, Tomas Pärt and Ben C. Sheldon

Cross-modal and cross-temporal association in neurons of frontal cortex pp. 347-351

Joaquín M. Fuster, Mark Bodner and James K. Kroger

Phenotypic suppression of empty spiracles is prevented by buttonhead pp. 351-354

Frieder Schöck, Joachim Reischl, Ernst Wimmer, Heike Taubert, Beverly A. Purnell and Herbert Jäckle

Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases pp. 354-360

Akihiko Taguchi, David C. Blood, Gustavo del Toro, Anthony Canet, Daniel C. Lee, Wu Qu, Nozomu Tanji, Yan Lu, Evanthia Lalla, Caifeng Fu, Marion A. Hofmann, Thomas Kislinger, Mark Ingram, Amy Lu, Hidekazu Tanaka, Osamu Hori, Satoshi Ogawa, David M. Stern and Ann Marie Schmidt

Neurotoxicity induces cleavage of p35 to p25 by calpain pp. 360-364

Ming-sum Lee, Young T. Kwon, Mingwei Li, Junmin Peng, Robert M. Friedlander and Li-Huei Tsai

LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway pp. 364-368

Andrei G. Petcherski and Judith Kimble

Translocation step size and mechanism of the RecBC DNA helicase pp. 368-372

Piero R. Bianco and Stephen C. Kowalczykowski

The crystal structure of the photoprotein aequorin at 2.3 Å resolution pp. 372-376

James F. Head, Satoshi Inouye, Katsunori Teranishi and Osamu Shimomura

Erratum: The ecological cost of sex pp. 376-376

C. Patrick Doncaster, Graeme E. Pound and Simon J. Cox

2000, volume 405, articles 6783

…as editor defends publishing key AZT paper pp. 105-105

Natasha Loder

South Africa turns to research in the hope of settling AIDS policy… pp. 105-106

Michael Cherry

French research minister targets IT and biotech pp. 106-106

Heather McCabe

Canada's plans for neutrons stall pp. 107-108

Colin Macilwain

German Greens go cold on nuclear fusion pp. 107-107

Quirin Schiermeier

US reforms rules for telling public about GM food pp. 108-108

Colin Macilwain

Italian genomics boost retained pp. 108-109

Alison Abbott

Israel debates raising commitment to CERN pp. 109-109

Haim Watzman

Troubled US fusion project receives cash injection pp. 110-110

Colin Macilwain

Medical tests cost Lawrence Berkeley $2.2 million pp. 110-110

Sally Lehrman

Australia improves its AIMS pp. 110-110

Peter Pockley

Souped-up search engines pp. 113-114

Declan Butler

We urgently need more data to improve the lives of laboratory animals pp. 116-116

Enrico Alleva and Augusto Vitale

Planck family paid a high price for opposing Hitler pp. 116-116

William Steinsmith

How to make diplomats scientifically literate pp. 116-116

Peter Cohen

Science's neglected legacy pp. 117-120

Stephen M. Maurer, Richard B. Firestone and Charles R. Scriver

Battle of the bones pp. 121-122

Kevin Padian

An ignoble lineage pp. 122-123

Leo Kinlen

A sermon on the mounts pp. 123-123

Chris Paola

On the scent of the sixth sense pp. 124-124

Michael Stoddart

Horse power pp. 125-125

Vaclav Smil

Disextinction, Inc pp. 127-127

Kathryn Cramer

Designed to dissolve pp. 129-130

Walter Leitner

Tuning in with motor proteins pp. 131-133

Matthew Holley

The dark side of distortion pp. 133-134

Max Tegmark

The rise of the hybrid fungi pp. 134-135

Clive Brasier

Exploring phase space pp. 135-137

Michael F. Shlesinger

Mutant weed breaks silence pp. 137-138

Susan Tweedie and Adrian Bird

Moving pictures pp. 138-138

David Jones

Lie detection and language comprehension pp. 139-139

Nancy L. Etcoff, Paul Ekman, John J. Magee and Mark G. Frank

Formation of endothelial cell networks pp. 139-141

Gabriel Helmlinger, Mitsuhiro Endo, Napoleone Ferrara, Lynn Hlatky and Rakesh K. Jain

Chernobyl's legacy in food and water pp. 141-141

J. T. Smith, R. N. J. Comans, N. A. Beresford, S. M. Wright, B. J. Howard and W. C. Camplin

Detection of weak gravitational lensing distortions of distant galaxies by cosmic dark matter at large scales pp. 143-148

David M. Wittman, J. Anthony Tyson, David Kirkman, Ian Dell'Antonio and Gary Bernstein

Prestin is the motor protein of cochlear outer hair cells pp. 149-155

Jing Zheng, Weixing Shen, David Z. Z. He, Kevin B. Long, Laird D. Madison and Peter Dallos

Cosmic γ-ray background from structure formation in the intergalactic medium pp. 156-158

Abraham Loeb and Eli Waxman

Proximate humid and dry regions in Jupiter's atmosphere indicate complex local meteorology pp. 158-160

M. Roos-Serote, A. R. Vasavada, L. Kamp, P. Drossart, P. Irwin, C. Nixon and R. W. Carlson

Closing the spin gap in the Kondo insulator Ce3Bi4Pt3 at high magnetic fields pp. 160-163

Marcelo Jaime, Roman Movshovich, Gregory R. Stewart, Ward P. Beyermann, Mariano Gomez Berisso, Michael F. Hundley, Paul C. Canfield and John L. Sarrao

Relaxation in polymer electrolytes on the nanosecond timescale pp. 163-165

Guomin Mao, Ricardo Fernandez Perea, W. Spencer Howells, David L. Price and Marie-Louise Saboungi

Non-fluorous polymers with very high solubility in supercritical CO2 down to low pressures pp. 165-168

Traian Sarbu, Thomas Styranec and Eric J. Beckman

Resolving the ‘opal paradox’ in the Southern Ocean pp. 168-172

Philippe Pondaven, Olivier Ragueneau, Paul Tréguer, Anne Hauvespre, Laurent Dezileau and Jean Louis Reyss

Constraints on the composition of the Earth's core from ab initio calculations pp. 172-175

D. Alfè, M. J. Gillan and G. D. Price

Detection and classification of atmospheric methane oxidizing bacteria in soil pp. 175-178

Ian D. Bull, Nisha R. Parekh, Grahame H. Hall, Philip Ineson and Richard P. Evershed

Infectious parthenogenesis pp. 178-179

M. E. Huigens, R. F. Luck, R. H. G. Klaassen, M. F. P. M. Maas, M. J. T. N. Timmermans and R. Stouthamer

Rewarding effects of opiates are absent in mice lacking the receptor for substance P pp. 180-183

Patricia Murtra, Anne M. Sheasby, Stephen P. Hunt and Carmen De Felipe

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia pp. 183-187

John B. Davis, Julie Gray, Martin J. Gunthorpe, Jonathan P. Hatcher, Phil T. Davey, Philip Overend, Mark H. Harries, Judi Latcham, Colin Clapham, Kirsty Atkinson, Stephen A. Hughes, Kim Rance, Evelyn Grau, Alex J. Harper, Perdita L. Pugh, Derek C. Rogers, Sharon Bingham, Andrew Randall and Steven A. Sheardown

Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus pp. 187-191

Dwight E. Bergles, J. David B. Roberts, Peter Somogyi and Craig E. Jahr

Fringe forms a complex with Notch pp. 191-195

Bong-Gun Ju, Sangyun Jeong, Eunkyung Bae, Seogang Hyun, Sean B. Carroll, Jeongbin Yim and Jaeseob Kim

ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation pp. 195-200

Hiroaki Kawasaki, Lou Schiltz, Robert Chiu, Keiichi Itakura, Kazunari Taira, Yoshihiro Nakatani and Kazunari K. Yokoyama

B and C floral organ identity functions require SEPALLATA MADS-box genes pp. 200-203

Soraya Pelaz, Gary S. Ditta, Elvira Baumann, Ellen Wisman and Martin F. Yanofsky

Disruption of the plant gene MOM releases transcriptional silencing of methylated genes pp. 203-206

Paolo Amedeo, Yoshiki Habu, Karin Afsar, Ortrun Mittelsten Scheid and Jerzy Paszkowski

Causes, consequences and ethics of biodiversity pp. 208-211

David Tilman

Getting the measure of biodiversity pp. 212-219

Andy Purvis and Andy Hector

Global patterns in biodiversity pp. 220-227

Kevin J. Gaston

The diversity–stability debate pp. 228-233

Kevin Shear McCann

Consequences of changing biodiversity pp. 234-242

F. Stuart Chapin, Erika S. Zavaleta, Valerie T. Eviner, Rosamond L. Naylor, Peter M. Vitousek, Heather L. Reynolds, David U. Hooper, Sandra Lavorel, Osvaldo E. Sala, Sarah E. Hobbie, Michelle C. Mack and Sandra Díaz

Systematic conservation planning pp. 243-253

C. R. Margules and R. L. Pressey

Investing in Conservation Solutions pp. 254-254

Peter Seligmann and Gustavo A. B. da Fonseca

Integrating Science and Conservation pp. 254-254

Gordon Moore and Edward O. Wilson

Conservation International and Biodiversity Conservation pp. 254-254

Russell A. Mittermeier

Are mega-mergers good medicine for the pharmaceutical industry? pp. 257-258

Diane Gershon

What are you worth to your employer? pp. 258-258

Diane Gershon

Partners resolve their differences and unite at the second attempt pp. 258-258

Diane Gershon

2000, volume 405, articles 6782

NIH opposes plans for patenting ‘similar’ gene sequences pp. 3-3

David Dickson

Shareholder sues Celera over loss pp. 3-3

Paul Smaglik

Doubts and uncertainties slow NASA's schedule pp. 4-4

Tony Reichhardt

Spain gives science and technology a ministry of its own pp. 4-4

Xavier Bosch

New panel set to beat biotech's bad image… pp. 5-5

Quirin Schiermeier

… as European public remains sceptical pp. 5-5

Heather McCabe

Battle lines shift in stem-cell funding fight… pp. 6-6

Paul Smaglik

… as non-profit companies enter the fray pp. 6-6

Paul Smaglik

CJD survey offers Britain a glimmer of hope pp. 7-7

Peter Aldhous

Space-station airlock to serve as temporary lab pp. 7-7

Alison Abbott

NSF celebrates half a century with big plans pp. 8-8

Colin Macilwain

The missionary from Munich pp. 10-11

Alison Abbott

How metrics could have saved UK car industry pp. 13-14

Michael T. Knowles

Sagan breached security by revealing US work on a lunar bomb project pp. 13-13

Leonard Reiffel

Austria takes lab animal welfare seriously pp. 13-13

Wolf Frühauf

Instrument's ability to do the job is NASA's priority pp. 14-14

Donald A. Kniffen

Putting marine mammals back in the mainstream pp. 14-14

David W. Sims

Persian role in flowering of Islamic science pp. 14-14

Saadi Khochbin

Hell-fire and medication pp. 15-16

Ryan J. Huxtable

Tales from a continental drifter pp. 16-17

Alan Longhurst

Winging their way pp. 17-18

R. McNeill Alexander

Strolling through the bioenergy field pp. 18-18

Paul D. Boyer

Oeconomia Naturae L pp. 19-19

Geir Hestmark

Et in articulo mortis pp. 21-21

Han Yu

Evolution all at sea pp. 23-24

Richard D. Norris and Colomban de Vargas

Coasting out of Africa pp. 25-27

Chris Stringer

Turbulence without inertia pp. 27-28

Ronald G. Larson

Gone but not forgotten pp. 28-29

Douglas R. Green and Helen M. Beere

How far to the cosmic lighthouse? pp. 29-29

Sarah Tomlin

Strength of the San Andreas pp. 31-32

Mark D. Zoback

A single birth of all plastids? pp. 32-33

Jeffrey D. Palmer

A flicker of interest pp. 33-33

David Jones

Jane Gray (1929–2000) pp. 34-34

William A. Shear

Beetle larvae cooperate to mimic bees pp. 35-36

John Hafernik and Leslie Saul-Gershenz

Coral bleach-out in Belize pp. 36-36

Richard B. Aronson, William F. Precht, Ian G. Macintyre and Thaddeus J. T. Murdoch

Transgenerational mutation by radiation pp. 37-37

Yuri E. Dubrova, Mark Plumb, Bruno Gutierrez, Emma Boulton and Alec J. Jeffreys

Spontaneous formation of inorganic helices pp. 38-38

Oscar Giraldo, Stephanie L. Brock, Manuel Marquez, Steven L. Suib, Hugh Hillhouse and Michael Tsapatsis

Erratum: Stomach rinsing in rays pp. 38-38

David W. Sims, Paul L. R. Andrews and J. Z. Young

A surprising simplicity to protein folding pp. 39-42

David Baker

Molecular evidence for genetic mixing of Arctic and Antarctic subpolar populations of planktonic foraminifers pp. 43-47

Kate F. Darling, Christopher M. Wade, Iain A. Stewart, Dick Kroon, Richard Dingle and Andrew J. Leigh Brown

Io as a source of the jovian dust streams pp. 48-50

A. L. Graps, E. Grün, H. Svedhem, H. Krüger, M. Horányi, A. Heck and S. Lammers

Detection of doubled shot noise in short normal-metal/ superconductor junctions pp. 50-53

X. Jehl, M. Sanquer, R. Calemczuk and D. Mailly

Elastic turbulence in a polymer solution flow pp. 53-55

A. Groisman and V. Steinberg

Rapid prototyping of patterned functional nanostructures pp. 56-60

Hongyou Fan, Yunfeng Lu, Aaron Stump, Scott T. Reed, Tom Baer, Randy Schunk, Victor Perez-Luna, Gabriel P. López and C. Jeffrey Brinker

Large differences in tropical aerosol forcing at the top of the atmosphere and Earth's surface pp. 60-63

S. K. Satheesh and V. Ramanathan

Sensitivity of the geomagnetic axial dipole to thermal core–mantle interactions pp. 63-65

Jeremy Bloxham

Early human occupation of the Red Sea coast of Eritrea during the last interglacial pp. 65-69

Robert C. Walter, Richard T. Buffler, J. Henrich Bruggemann, Mireille M. M. Guillaume, Seife M. Berhe, Berhane Negassi, Yoseph Libsekal, Hai Cheng, R. Lawrence Edwards, Rudo von Cosel, Didier Néraudeau and Mario Gagnon

The origin of red algae and the evolution of chloroplasts pp. 69-72

David Moreira, Hervé Le Guyader and Hervé Philippe

Encoding of movement time by populations of cerebellar Purkinje cells pp. 72-76

Peter Thier, Peter W. Dicke, Roman Haas and Shabtai Barash

Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation pp. 76-81

Carl-Philipp Heisenberg, Masazumi Tada, Gerd-Jörg Rauch, Leonor Saúde, Miguel L. Concha, Robert Geisler, Derek L. Stemple, James C. Smith and Stephen W. Wilson

Dishevelled controls cell polarity during Xenopus gastrulation pp. 81-85

John B. Wallingford, Brian A. Rowning, Kevin M. Vogeli, Ute Rothbächer, Scott E. Fraser and Richard M. Harland

A receptor for phosphatidylserine-specific clearance of apoptotic cells pp. 85-90

Valerie A. Fadok, Donna L. Bratton, David M. Rose, Alan Pearson, R. Alan B. Ezekewitz and Peter M. Henson

JNK is required for effector T-cell function but not for T-cell activation pp. 91-94

Chen Dong, Derek D. Yang, Cathy Tournier, Alan J. Whitmarsh, Jie Xu, Roger J. Davis and Richard A. Flavell

A role for excreted quinones in extracellular electron transfer pp. 94-97

Dianne K. Newman and Roberto Kolter

Structural insights into the stereochemistry of the cyclooxygenase reaction pp. 97-101

James R. Kiefer, Jennifer L. Pawlitz, Kirby T. Moreland, Roderick A. Stegeman, William F. Hood, James K. Gierse, Anna M. Stevens, Douglas C. Goodwin, Scott W. Rowlinson, Lawrence J. Marnett, William C. Stallings and Ravi G. Kurumbail

Erratum: The earliest angiosperms: evidence from mitochondrial, plastid and nuclear genomes pp. 101-101

Yin-Long Qiu, Jungho Lee, Fabiana Bernasconi-Quadroni, Douglas E. Soltis, Pamela S. Soltis, Michael Zanis, Elizabeth A. Zimmer, Zhiduan Chen, Vincent Savolainen and Mark W. Chase