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2016, volume 538, articles 7626

Parkinson's disease pp. S1-S1

Michelle Grayson

How foreign is the past? pp. E1-E2

Richard J. Telford, Joseph D. Chipperfield, Hilary H. Birks and H. John B. Birks

Two hundred steps pp. S2-S3

Liam Drew

Lyons et al. reply pp. E3-E4

S. Kathleen Lyons, Joshua H. Miller, Kathryn L. Amatange, Anna K. Behrensmeyer, Antoine Bercovici, Jessica L. Blois, Matt Davis, William DiMichele, Andrew Du, Jussi T. Eronen, J. Tyler Faith, Gary R. Graves, Nathan Jud, Conrad Labandeira, Cindy V. Looy, Brian McGill, David Patterson, Silvia Pineda-Munoz, Richard Potts, Brett Riddle, Rebecca Terry, Anikó Tóth, Werner Ulrich, Amelia Villaseñor, Scott Wing, Heidi Anderson, John Anderson and Nicholas J. Gotelli

Perspective: Data sharing for discovery pp. S4-S4

Mark Frasier

Diagnosis: Warning signs pp. S5-S7

Katherine Bourzac

Technology: Monitoring gets personal pp. S8-S10

Lauren Gravitz

Electrotherapy: Shock value pp. S10-S12

Michael Eisenstein

Pathology: The prion principle pp. S13-S16

Simon Makin

Parkinson's disease: 4 big questions pp. S17-S17

Sarah Deweerdt

Australia & New Zealand pp. S49-S49

Nicky Phillips

Southern stars pp. S50-S51

Amanda Rider

Sydney & Melbourne: A tale of two cities pp. S58-S65

Annabel McGilvray

A well-feathered nest pp. S70-S70

Bianca Nogrady

The appliance of science in an outback kitchen pp. S72-S72

Viviane Richter

Clear vision from the end of the Earth pp. S74-S76

Linda Vergnani

Divisive campaigning damages democracy pp. 429-429

Andrew Daniller

Computing glitch may have doomed Mars lander pp. 435-436

Elizabeth Gibney

Scientific challenges loom for Canada’s popular prime minister pp. 436-437

Nicola Jones

@ScientistTrump will make science great again pp. 437-438

Sara Reardon

Icy heart could be key to Pluto’s strange geology pp. 439-439

Alexandra Witze

Europe’s drug regulator opens vaults of clinical-trials data pp. 440-440

Alison Abbott

Violence escalates at South African universities pp. 440-441

Sarah Wild

Young scientists under pressure: what the data show pp. 444-444

Brendan Maher and Miquel Sureda Anfres

Young, talented and fed-up: scientists tell their stories pp. 446-449

Kendall Powell

Let researchers try new paths pp. 451-453

Tolu Oni, Fabio Sciarrino, Gerardo Adesso and Rob Knight

Fewer numbers, better science pp. 453-455

Rinze Benedictus, Frank Miedema and Mark W. J. Ferguson

Economic history: The roots of growth pp. 456-457

Brad DeLong

Extremophiles: Life at the deep end pp. 457-457

Sonja-Verena Albers

Sustainability: Laying waste pp. 458-458

Edward Humes

UK research reforms in a Brexit world pp. 459-459

Venki Ramakrishnan

Religion and science: boost sustainability pp. 459-459

Emilio Chuvieco, Marcelo Sánchez Sorondo and Josef Settele

Religion and science: not a true dialogue pp. 459-459

David Lovelace

Open data: towards full transparency pp. 459-459

Timothy H. Parker, Shinichi Nakagawa and Jessica Gurevtich

Resistance to SI units pervades medicine pp. 459-459

Andreas Otte

Precision timing in a cell pp. 462-463

Xiaojing J. Gao and Michael B. Elowitz

Twenty-five years of low-cost solar cells pp. 463-464

Mohammad K. Nazeeruddin

Female genital cutting under the spotlight pp. 465-466

Nicholas A. Christakis

Birth of stellar siblings pp. 466-467

Adele Plunkett

Deep neural reasoning pp. 467-468

Herbert Jaeger

Ancient avian aria from Antarctica pp. 468-469

Patrick M. O'Connor

Hybrid computing using a neural network with dynamic external memory pp. 471-476

Alex Graves, Greg Wayne, Malcolm Reynolds, Tim Harley, Ivo Danihelka, Agnieszka Grabska-Barwińska, Sergio Gómez Colmenarejo, Edward Grefenstette, Tiago Ramalho, John Agapiou, Adrià Puigdomènech Badia, Karl Moritz Hermann, Yori Zwols, Georg Ostrovski, Adam Cain, Helen King, Christopher Summerfield, Phil Blunsom, Koray Kavukcuoglu and Demis Hassabis

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models pp. 477-482

András Kotschy, Zoltán Szlavik, James Murray, James Davidson, Ana Leticia Maragno, Gaëtane Le Toumelin-Braizat, Maïa Chanrion, Gemma L. Kelly, Jia-Nan Gong, Donia M. Moujalled, Alain Bruno, Márton Csekei, Attila Paczal, Zoltán B. Szabo, Szabolcs Sipos, Gábor Radics, Agnes Proszenyak, Balázs Balint, Levente Ondi, Gábor Blasko, Alan Robertson, Allan Surgenor, Pawel Dokurno, Ijen Chen, Natalia Matassova, Julia Smith, Christopher Pedder, Christopher Graham, Aurélie Studeny, Gaëlle Lysiak-Auvity, Anne-Marie Girard, Fabienne Gravé, David Segal, Chris D. Riffkin, Giovanna Pomilio, Laura C. A. Galbraith, Brandon J. Aubrey, Margs S. Brennan, Marco J. Herold, Catherine Chang, Ghislaine Guasconi, Nicolas Cauquil, Fabien Melchiore, Nolwen Guigal-Stephan, Brian Lockhart, Frédéric Colland, John A. Hickman, Andrew W. Roberts, David C. S. Huang, Andrew H. Wei, Andreas Strasser, Guillaume Lessene and Olivier Geneste

A triple protostar system formed via fragmentation of a gravitationally unstable disk pp. 483-486

John J. Tobin, Kaitlin M. Kratter, Magnus V. Persson, Leslie W. Looney, Michael M. Dunham, Dominique Segura-Cox, Zhi-Yun Li, Claire J. Chandler, Sarah I. Sadavoy, Robert J. Harris, Carl Melis and Laura M. Pérez

Potassium isotopic evidence for a high-energy giant impact origin of the Moon pp. 487-490

Kun Wang and Stein B. Jacobsen

Quantum dynamics of simultaneously measured non-commuting observables pp. 491-494

Shay Hacohen-Gourgy, Leigh S. Martin, Emmanuel Flurin, Vinay V. Ramasesh, K. Birgitta Whaley and Irfan Siddiqi

Atom-at-a-time laser resonance ionization spectroscopy of nobelium pp. 495-498

Mustapha Laatiaoui, Werner Lauth, Hartmut Backe, Michael Block, Dieter Ackermann, Bradley Cheal, Premaditya Chhetri, Christoph Emanuel Düllmann, Piet van Duppen, Julia Even, Rafael Ferrer, Francesca Giacoppo, Stefan Götz, Fritz Peter Heßberger, Mark Huyse, Oliver Kaleja, Jadambaa Khuyagbaatar, Peter Kunz, Felix Lautenschläger, Andrew Kishor Mistry, Sebastian Raeder, Enrique Minaya Ramirez, Thomas Walther, Calvin Wraith and Alexander Yakushev

Projected land photosynthesis constrained by changes in the seasonal cycle of atmospheric CO2 pp. 499-501

Sabrina Wenzel, Peter M. Cox, Veronika Eyring and Pierre Friedlingstein

Fossil evidence of the avian vocal organ from the Mesozoic pp. 502-505

Julia A. Clarke, Sankar Chatterjee, Zhiheng Li, Tobias Riede, Federico Agnolin, Franz Goller, Marcelo P. Isasi, Daniel R. Martinioni, Francisco J. Mussel and Fernando E. Novas

Changing cultural attitudes towards female genital cutting pp. 506-509

Sonja Vogt, Nadia Ahmed Mohmmed Zaid, Hilal El Fadil Ahmed, Ernst Fehr and Charles Efferson

Genomic insights into the peopling of the Southwest Pacific pp. 510-513

Pontus Skoglund, Cosimo Posth, Kendra Sirak, Matthew Spriggs, Frederique Valentin, Stuart Bedford, Geoffrey R. Clark, Christian Reepmeyer, Fiona Petchey, Daniel Fernandes, Qiaomei Fu, Eadaoin Harney, Mark Lipson, Swapan Mallick, Mario Novak, Nadin Rohland, Kristin Stewardson, Syafiq Abdullah, Murray P. Cox, Françoise R. Friedlaender, Jonathan S. Friedlaender, Toomas Kivisild, George Koki, Pradiptajati Kusuma, D. Andrew Merriwether, Francois-X. Ricaut, Joseph T. S. Wee, Nick Patterson, Johannes Krause, Ron Pinhasi and David Reich

Synchronous long-term oscillations in a synthetic gene circuit pp. 514-517

Laurent Potvin-Trottier, Nathan D. Lord, Glenn Vinnicombe and Johan Paulsson

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments pp. 518-522

Edwin D. Hawkins, Delfim Duarte, Olufolake Akinduro, Reema A. Khorshed, Diana Passaro, Malgorzata Nowicka, Lenny Straszkowski, Mark K. Scott, Steve Rothery, Nicola Ruivo, Katie Foster, Michaela Waibel, Ricky W. Johnstone, Simon J. Harrison, David A. Westerman, Hang Quach, John Gribben, Mark D. Robinson, Louise E. Purton, Dominique Bonnet and Cristina Lo Celso

Chromosome conformation elucidates regulatory relationships in developing human brain pp. 523-527

Hyejung Won, Luis de la Torre-Ubieta, Jason L. Stein, Neelroop N. Parikshak, Jerry Huang, Carli K. Opland, Michael J. Gandal, Gavin J. Sutton, Farhad Hormozdiari, Daning Lu, Changhoon Lee, Eleazar Eskin, Irina Voineagu, Jason Ernst and Daniel H. Geschwind

TET-mediated DNA demethylation controls gastrulation by regulating Lefty–Nodal signalling pp. 528-532

Hai-Qiang Dai, Bang-An Wang, Lu Yang, Jia-Jia Chen, Guo-Chun Zhu, Mei-Ling Sun, Hao Ge, Rui Wang, Deborah L. Chapman, Fuchou Tang, Xin Sun and Guo-Liang Xu

Mechanism for DNA transposons to generate introns on genomic scales pp. 533-536

Jason T. Huff, Daniel Zilberman and Scott W. Roy

Pore architecture of TRIC channels and insights into their gating mechanism pp. 537-541

Hanting Yang, Miaohui Hu, Jianli Guo, Xiaomin Ou, Tanxi Cai and Zhenfeng Liu

Correction: Corrigendum: Holocene shifts in the assembly of plant and animal communities implicate human impacts pp. 542-542

S. Kathleen Lyons, Kathryn L. Amatangelo, Anna K. Behrensmeyer, Antoine Bercovici, Jessica L. Blois, Matt Davis, William A. DiMichele, Andrew Du, Jussi T. Eronen, J. Tyler Faith, Gary R. Graves, Nathan Jud, Conrad Labandeira, Cindy V. Looy, Brian McGill, Joshua H. Miller, David Patterson, Silvia Pineda-Munoz, Richard Potts, Brett Riddle, Rebecca Terry, Anikó Tóth, Werner Ulrich, Amelia Villaseñor, Scott Wing, Heidi Anderson, John Anderson, Donald Waller and Nicholas J. Gotelli

Correction: Corrigendum: Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease pp. 542-542

Louise A. Hyslop, Paul Blakeley, Lyndsey Craven, Jessica Richardson, Norah M. E. Fogarty, Elpida Fragouli, Mahdi Lamb, Sissy E. Wamaitha, Nilendran Prathalingam, Qi Zhang, Hannah O’Keefe, Yuko Takeda, Lucia Arizzi, Samer Alfarawati, Helen A. Tuppen, Laura Irving, Dimitrios Kalleas, Meenakshi Choudhary, Dagan Wells, Alison P. Murdoch, Douglass M. Turnbull, Kathy K. Niakan and Mary Herbert

Erratum: Structure of the adenosine A2A receptor bound to an engineered G protein pp. 542-542

Byron Carpenter, Rony Nehmé, Tony Warne, Andrew G. W. Leslie and Christopher G. Tate

Agents of change pp. 543-545

Virginia Gewin

Turning point: Cream of the crop pp. 545-545

Virginia Gewin

The offering pp. 548-548

Hall Jameson

2016, volume 538, articles 7625

Arecibo Observatory hit with discrimination lawsuit pp. 297-298

Traci Watson

The scientists who support Donald Trump pp. 298-299

Sara Reardon

How Republicans reshaped the House science committee pp. 300-300

Jeff Tollefson

Mouse eggs made from skin cells in a dish pp. 301-301

David Cyranoski

Science group seeks to guide Silicon Valley philanthropists pp. 302-302

Erika Check Hayden

Effort to wrangle geoscience data faces uncertain future pp. 303-303

Alexandra Witze

The polling crisis: How to tell what people really think pp. 304-306

Ramin Skibba

The power of prediction markets pp. 308-310

Adam Mann

There is a blind spot in AI research pp. 311-313

Kate Crawford and Ryan Calo

Natural history: Voices from the greenwood pp. 314-315

Caspar Henderson

Biomechanics: The wonders of whirl pp. 315-315

John E. Moalli and Adam P. Summers

Q&A: Lexi Jamieson Marsh and Ellen Currano: Face to face pp. 316-316

Alexandra Witze

Two African elephant species, not just one pp. 317-317

Colin P. Groves

Include social equity in California Biohub pp. 317-317

Science Fare

Soil clean-up needs cash and clarity pp. 317-317

Changsheng Qu, Shui Wang and Peter Engelund Holm

Species loss: learn from health metrics pp. 317-317

Kathryn J. Fiorella, Giovanni Rapacciuolo and Christopher Trisos

Martian dance of fiction and fact pp. 317-317

Jonathan Cowie

Deborah S. Jin 1968–2016 pp. 318-318

Brian DeMarco, John Bohn and Eric Cornell

A matched set of frog sequences pp. 320-321

Shawn Burgess

Unexpected X-ray flares pp. 321-322

Sergio Campana

A shocking protein complex pp. 322-323

Kai Bartkowiak and Klaus Pantel

Chemical diversity targets malaria pp. 323-325

David A. Fidock

Speedy electrons exposed in a flash pp. 325-326

Michael Chini

The organelle replication connection pp. 326-327

Elena Ziviani and Luca Scorrano

Accurate de novo design of hyperstable constrained peptides pp. 329-335

Gaurav Bhardwaj, Vikram Khipple Mulligan, Christopher D. Bahl, Jason M. Gilmore, Peta J. Harvey, Olivier Cheneval, Garry W. Buchko, Surya V. S. R. K. Pulavarti, Quentin Kaas, Alexander Eletsky, Po-Ssu Huang, William A. Johnsen, Per Jr Greisen, Gabriel J. Rocklin, Yifan Song, Thomas W. Linsky, Andrew Watkins, Stephen A. Rettie, Xianzhong Xu, Lauren P. Carter, Richard Bonneau, James M. Olson, Evangelos Coutsias, Colin E. Correnti, Thomas Szyperski, David J. Craik and David Baker

Genome evolution in the allotetraploid frog Xenopus laevis pp. 336-343

Adam M. Session, Yoshinobu Uno, Taejoon Kwon, Jarrod A. Chapman, Atsushi Toyoda, Shuji Takahashi, Akimasa Fukui, Akira Hikosaka, Atsushi Suzuki, Mariko Kondo, Simon J. van Heeringen, Ian Quigley, Sven Heinz, Hajime Ogino, Haruki Ochi, Uffe Hellsten, Jessica B. Lyons, Oleg Simakov, Nicholas Putnam, Jonathan Stites, Yoko Kuroki, Toshiaki Tanaka, Tatsuo Michiue, Minoru Watanabe, Ozren Bogdanovic, Ryan Lister, Georgios Georgiou, Sarita S. Paranjpe, Ila van Kruijsbergen, Shengquiang Shu, Joseph Carlson, Tsutomu Kinoshita, Yuko Ohta, Shuuji Mawaribuchi, Jerry Jenkins, Jane Grimwood, Jeremy Schmutz, Therese Mitros, Sahar V. Mozaffari, Yutaka Suzuki, Yoshikazu Haramoto, Takamasa S. Yamamoto, Chiyo Takagi, Rebecca Heald, Kelly Miller, Christian Haudenschild, Jacob Kitzman, Takuya Nakayama, Yumi Izutsu, Jacques Robert, Joshua Fortriede, Kevin Burns, Vaneet Lotay, Kamran Karimi, Yuuri Yasuoka, Darwin S. Dichmann, Martin F. Flajnik, Douglas W. Houston, Jay Shendure, Louis DuPasquier, Peter D. Vize, Aaron M. Zorn, Michihiko Ito, Edward M. Marcotte, John B. Wallingford, Yuzuru Ito, Makoto Asashima, Naoto Ueno, Yoichi Matsuda, Gert Jan C. Veenstra, Asao Fujiyama, Richard M. Harland, Masanori Taira and Daniel S. Rokhsar

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors pp. 344-349

Nobutaka Kato, Eamon Comer, Tomoyo Sakata-Kato, Arvind Sharma, Manmohan Sharma, Micah Maetani, Jessica Bastien, Nicolas M. Brancucci, Joshua A. Bittker, Victoria Corey, David Clarke, Emily R. Derbyshire, Gillian L. Dornan, Sandra Duffy, Sean Eckley, Maurice A. Itoe, Karin M. J. Koolen, Timothy A. Lewis, Ping S. Lui, Amanda K. Lukens, Emily Lund, Sandra March, Elamaran Meibalan, Bennett C. Meier, Jacob A. McPhail, Branko Mitasev, Eli L. Moss, Morgane Sayes, Yvonne Van Gessel, Mathias J. Wawer, Takashi Yoshinaga, Anne-Marie Zeeman, Vicky M. Avery, Sangeeta N. Bhatia, John E. Burke, Flaminia Catteruccia, Jon C. Clardy, Paul A. Clemons, Koen J. Dechering, Jeremy R. Duvall, Michael A. Foley, Fabian Gusovsky, Clemens H. M. Kocken, Matthias Marti, Marshall L. Morningstar, Benito Munoz, Daniel E. Neafsey, Amit Sharma, Elizabeth A. Winzeler, Dyann F. Wirth, Christina A. Scherer and Stuart L. Schreiber

Frizzled proteins are colonic epithelial receptors for C. difficile toxin B pp. 350-355

Liang Tao, Jie Zhang, Paul Meraner, Alessio Tovaglieri, Xiaoqian Wu, Ralf Gerhard, Xinjun Zhang, William B. Stallcup, Ji Miao, Xi He, Julian G. Hurdle, David T. Breault, Abraham L. Brass and Min Dong

Ultraluminous X-ray bursts in two ultracompact companions to nearby elliptical galaxies pp. 356-358

Jimmy A. Irwin, W. Peter Maksym, Gregory R. Sivakoff, Aaron J. Romanowsky, Dacheng Lin, Tyler Speegle, Ian Prado, David Mildebrath, Jay Strader, Jifeng Liu and Jon M. Miller

Multi-petahertz electronic metrology pp. 359-363

M. Garg, M. Zhan, T. T. Luu, H. Lakhotia, T. Klostermann, A. Guggenmos and E. Goulielmakis

Real-space investigation of energy transfer in heterogeneous molecular dimers pp. 364-367

Hiroshi Imada, Kuniyuki Miwa, Miyabi Imai-Imada, Shota Kawahara, Kensuke Kimura and Yousoo Kim

Asthenosphere rheology inferred from observations of the 2012 Indian Ocean earthquake pp. 368-372

Yan Hu, Roland Bürgmann, Paramesh Banerjee, Lujia Feng, Emma M. Hill, Takeo Ito, Takao Tabei and Kelin Wang

Upper-mantle water stratification inferred from observations of the 2012 Indian Ocean earthquake pp. 373-377

Sagar Masuti, Sylvain D. Barbot, Shun-ichiro Karato, Lujia Feng and Paramesh Banerjee

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns pp. 378-382

Faiyaz Notta, Michelle Chan-Seng-Yue, Mathieu Lemire, Yilong Li, Gavin W. Wilson, Ashton A. Connor, Robert E. Denroche, Sheng-Ben Liang, Andrew M. K. Brown, Jaeseung C. Kim, Tao Wang, Jared T. Simpson, Timothy Beck, Ayelet Borgida, Nicholas Buchner, Dianne Chadwick, Sara Hafezi-Bakhtiari, John E. Dick, Lawrence Heisler, Michael A. Hollingsworth, Emin Ibrahimov, Gun Ho Jang, Jeremy Johns, Lars G. T. Jorgensen, Calvin Law, Olga Ludkovski, Ilinca Lungu, Karen Ng, Danielle Pasternack, Gloria M. Petersen, Liran I. Shlush, Lee Timms, Ming-Sound Tsao, Julie M. Wilson, Christina K. Yung, George Zogopoulos, John M. S. Bartlett, Ludmil B. Alexandrov, Francisco X. Real, Sean P. Cleary, Michael H. Roehrl, John D. McPherson, Lincoln D. Stein, Thomas J. Hudson, Peter J. Campbell and Steven Gallinger

Cortico-fugal output from visual cortex promotes plasticity of innate motor behaviour pp. 383-387

Bao-hua Liu, Andrew D. Huberman and Massimo Scanziani

Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts pp. 388-391

Yuji Shiba, Toshihito Gomibuchi, Tatsuichiro Seto, Yuko Wada, Hajime Ichimura, Yuki Tanaka, Tatsuki Ogasawara, Kenji Okada, Naoko Shiba, Kengo Sakamoto, Daisuke Ido, Takashi Shiina, Masamichi Ohkura, Junichi Nakai, Narumi Uno, Yasuhiro Kazuki, Mitsuo Oshimura, Itsunari Minami and Uichi Ikeda

Fetal liver endothelium regulates the seeding of tissue-resident macrophages pp. 392-396

Pia Rantakari, Norma Jäppinen, Emmi Lokka, Elias Mokkala, Heidi Gerke, Emilia Peuhu, Johanna Ivaska, Kati Elima, Kaisa Auvinen and Marko Salmi

The epichaperome is an integrated chaperome network that facilitates tumour survival pp. 397-401

Anna Rodina, Tai Wang, Pengrong Yan, Erica DaGama Gomes, Mark P. S. Dunphy, Nagavarakishore Pillarsetty, John Koren, John F. Gerecitano, Tony Taldone, Hongliang Zong, Eloisi Caldas-Lopes, Mary Alpaugh, Adriana Corben, Matthew Riolo, Brad Beattie, Christina Pressl, Radu I. Peter, Chao Xu, Robert Trondl, Hardik J. Patel, Fumiko Shimizu, Alexander Bolaender, Chenghua Yang, Palak Panchal, Mohammad F. Farooq, Sarah Kishinevsky, Shanu Modi, Oscar Lin, Feixia Chu, Sujata Patil, Hediye Erdjument-Bromage, Pat Zanzonico, Clifford Hudis, Lorenz Studer, Gail J. Roboz, Ethel Cesarman, Leandro Cerchietti, Ross Levine, Ari Melnick, Steven M. Larson, Jason S. Lewis, Monica L. Guzman and Gabriela Chiosis

Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne pp. 402-405

Tycho E. T. Mevissen, Yogesh Kulathu, Monique P.C. Mulder, Paul P. Geurink, Sarah L. Maslen, Malte Gersch, Paul R. Elliott, John E. Burke, Bianca D. M. van Tol, Masato Akutsu, Farid El Oualid, Masato Kawasaki, Stefan M.V. Freund, Huib Ovaa and David Komander

Atomic structure of the entire mammalian mitochondrial complex I pp. 406-410

Karol Fiedorczuk, James A. Letts, Gianluca Degliesposti, Karol Kaszuba, Mark Skehel and Leonid A. Sazanov

X-ray structure of the human α4β2 nicotinic receptor pp. 411-415

Claudio L. Morales-Perez, Colleen M. Noviello and Ryan E. Hibbs

Addendum: Non-Joulian magnetostriction pp. 416-416

Harsh Deep Chopra and Manfred Wuttig

For your information pp. 417-418

Peter Fiske

The most important thing pp. 420-420

Marissa Lingen

2016, volume 538, articles 7624

It’s time to get real about conservation pp. 141-141

Aaron M. Ellison

Brexit government’s anti-immigration stance spooks UK scientists pp. 147-148

Daniel Cressey

South Africa plans health study to track half a million people pp. 148-149

Linda Nordling

NASA rethinks approach to Mars exploration pp. 149-150

Alexandra Witze

Safety concerns blight promising cancer therapy pp. 150-151

Heidi Ledford

Where Nobel winners get their start pp. 152-152

Tom Clynes

World’s tiniest machines win chemistry Nobel pp. 152-153

Richard Van Noorden and Davide Castelvecchi

A radical revision of human genetics pp. 154-157

Erika Check Hayden

The mental-health crisis among migrants pp. 158-160

Alison Abbott

Genomics is failing on diversity pp. 161-164

Alice B. Popejoy and Stephanie M. Fullerton

Scientists must have a say in the future of cities pp. 165-166

Timon McPhearson, Susan Parnell, David Simon, Owen Gaffney, Thomas Elmqvist, Xuemei Bai, Debra Roberts and Aromar Revi

Physics: Fallible pontiff of physics pp. 168-169

Graham Farmelo

Books in brief pp. 169-169

Barbara Kiser

History: Einstein the statesman pp. 170-170

Nancy Thorndike Greenspan

Don't let witch hunts taint investigations pp. 171-171

Kenneth Pimple

University on the rise without PhD students pp. 171-171

Steve Oppenheimer

Hasten end of dated fossil-fuel subsidies pp. 171-171

Tara Martin

Are farmed fish just for the wealthy? pp. 171-171

Ben Belton, Simon R. Bush and David C. Little

Are farmed fish just for the wealthy? Golden et al. reply pp. 171-171

Christopher Golden

Roger Yonchien Tsien (1952–2016) pp. 172-172

Timothy J. Rink, Louis Y. Tsien and Richard W. Tsien

Megafloods downsized pp. 174-175

J. Taylor Perron and Jeremy G. Venditti

Measuring our narrow strip of life pp. 175-176

S. Jay Olshansky

Fifty years of C4 photosynthesis pp. 177-179

Julian M. Hibberd and Robert T. Furbank

Moon churn pp. 177-177

Andrew Mitchinson

A map of human wanderlust pp. 179-180

Serena Tucci and Joshua M. Akey

Lethal violence deep in the human lineage pp. 180-181

Mark Pagel

In vitro and ex vivo strategies for intracellular delivery pp. 183-192

Martin P. Stewart, Armon Sharei, Xiaoyun Ding, Gaurav Sahay, Robert Langer and Klavs F. Jensen

The evolution of Ebola virus: Insights from the 2013–2016 epidemic pp. 193-200

Edward C. Holmes, Gytis Dudas, Andrew Rambaut and Kristian G. Andersen

The Simons Genome Diversity Project: 300 genomes from 142 diverse populations pp. 201-206

Swapan Mallick, Heng Li, Mark Lipson, Iain Mathieson, Melissa Gymrek, Fernando Racimo, Mengyao Zhao, Niru Chennagiri, Susanne Nordenfelt, Arti Tandon, Pontus Skoglund, Iosif Lazaridis, Sriram Sankararaman, Qiaomei Fu, Nadin Rohland, Gabriel Renaud, Yaniv Erlich, Thomas Willems, Carla Gallo, Jeffrey P. Spence, Yun S. Song, Giovanni Poletti, Francois Balloux, George van Driem, Peter de Knijff, Irene Gallego Romero, Aashish R. Jha, Doron M. Behar, Claudio M. Bravi, Cristian Capelli, Tor Hervig, Andres Moreno-Estrada, Olga L. Posukh, Elena Balanovska, Oleg Balanovsky, Sena Karachanak-Yankova, Hovhannes Sahakyan, Draga Toncheva, Levon Yepiskoposyan, Chris Tyler-Smith, Yali Xue, M. Syafiq Abdullah, Andres Ruiz-Linares, Cynthia M. Beall, Anna Di Rienzo, Choongwon Jeong, Elena B. Starikovskaya, Ene Metspalu, Jüri Parik, Richard Villems, Brenna M. Henn, Ugur Hodoglugil, Robert Mahley, Antti Sajantila, George Stamatoyannopoulos, Joseph T. S. Wee, Rita Khusainova, Elza Khusnutdinova, Sergey Litvinov, George Ayodo, David Comas, Michael F. Hammer, Toomas Kivisild, William Klitz, Cheryl A. Winkler, Damian Labuda, Michael Bamshad, Lynn B. Jorde, Sarah A. Tishkoff, W. Scott Watkins, Mait Metspalu, Stanislav Dryomov, Rem Sukernik, Lalji Singh, Kumarasamy Thangaraj, Svante Pääbo, Janet Kelso, Nick Patterson and David Reich

A genomic history of Aboriginal Australia pp. 207-214

Anna-Sapfo Malaspinas, Michael C. Westaway, Craig Muller, Vitor C. Sousa, Oscar Lao, Isabel Alves, Anders Bergström, Georgios Athanasiadis, Jade Y. Cheng, Jacob E. Crawford, Tim H. Heupink, Enrico Macholdt, Stephan Peischl, Simon Rasmussen, Stephan Schiffels, Sankar Subramanian, Joanne L. Wright, Anders Albrechtsen, Chiara Barbieri, Isabelle Dupanloup, Anders Eriksson, Ashot Margaryan, Ida Moltke, Irina Pugach, Thorfinn S. Korneliussen, Ivan P. Levkivskyi, J. Víctor Moreno-Mayar, Shengyu Ni, Fernando Racimo, Martin Sikora, Yali Xue, Farhang A. Aghakhanian, Nicolas Brucato, Søren Brunak, Paula F. Campos, Warren Clark, Sturla Ellingvåg, Gudjugudju Fourmile, Pascale Gerbault, Darren Injie, George Koki, Matthew Leavesley, Betty Logan, Aubrey Lynch, Elizabeth A. Matisoo-Smith, Peter J. McAllister, Alexander J. Mentzer, Mait Metspalu, Andrea B. Migliano, Les Murgha, Maude E. Phipps, William Pomat, Doc Reynolds, Francois-Xavier Ricaut, Peter Siba, Mark G. Thomas, Thomas Wales, Colleen Ma’run Wall, Stephen J. Oppenheimer, Chris Tyler-Smith, Richard Durbin, Joe Dortch, Andrea Manica, Mikkel H. Schierup, Robert A. Foley, Marta Mirazón Lahr, Claire Bowern, Jeffrey D. Wall, Thomas Mailund, Mark Stoneking, Rasmus Nielsen, Manjinder S. Sandhu, Laurent Excoffier, David M. Lambert and Eske Willerslev

Quantifying crater production and regolith overturn on the Moon with temporal imaging pp. 215-218

Emerson J. Speyerer, Reinhold Z. Povilaitis, Mark S. Robinson, Peter C. Thomas and Robert V. Wagner

Enhanced flexoelectric-like response in oxide semiconductors pp. 219-221

Jackeline Narvaez, Fabian Vasquez-Sancho and Gustau Catalan

Molecular transport through capillaries made with atomic-scale precision pp. 222-225

B. Radha, A. Esfandiar, F. C. Wang, A. P. Rooney, K. Gopinadhan, A. Keerthi, A. Mishchenko, A. Janardanan, P. Blake, L. Fumagalli, M. Lozada-Hidalgo, S. Garaj, S. J. Haigh, I. V. Grigorieva, H. A. Wu and A. K. Geim

Evolution of global temperature over the past two million years pp. 226-228

Carolyn W. Snyder

Progressive incision of the Channeled Scablands by outburst floods pp. 229-232

Isaac J. Larsen and Michael P. Lamb

The phylogenetic roots of human lethal violence pp. 233-237

José María Gómez, Miguel Verdú, Adela González-Megías and Marcos Méndez

Genomic analyses inform on migration events during the peopling of Eurasia pp. 238-242

Luca Pagani, Daniel John Lawson, Evelyn Jagoda, Alexander Mörseburg, Anders Eriksson, Mario Mitt, Florian Clemente, Georgi Hudjashov, Michael DeGiorgio, Lauri Saag, Jeffrey D. Wall, Alexia Cardona, Reedik Mägi, Melissa A. Wilson Sayres, Sarah Kaewert, Charlotte Inchley, Christiana L. Scheib, Mari Järve, Monika Karmin, Guy S. Jacobs, Tiago Antao, Florin Mircea Iliescu, Alena Kushniarevich, Qasim Ayub, Chris Tyler-Smith, Yali Xue, Bayazit Yunusbayev, Kristiina Tambets, Chandana Basu Mallick, Lehti Saag, Elvira Pocheshkhova, George Andriadze, Craig Muller, Michael C. Westaway, David M. Lambert, Grigor Zoraqi, Shahlo Turdikulova, Dilbar Dalimova, Zhaxylyk Sabitov, Gazi Nurun Nahar Sultana, Joseph Lachance, Sarah Tishkoff, Kuvat Momynaliev, Jainagul Isakova, Larisa D. Damba, Marina Gubina, Pagbajabyn Nymadawa, Irina Evseeva, Lubov Atramentova, Olga Utevska, François-Xavier Ricaut, Nicolas Brucato, Herawati Sudoyo, Thierry Letellier, Murray P. Cox, Nikolay A. Barashkov, Vedrana Škaro, Lejla Mulahasanovic´, Dragan Primorac, Hovhannes Sahakyan, Maru Mormina, Christina A. Eichstaedt, Daria V. Lichman, Syafiq Abdullah, Gyaneshwer Chaubey, Joseph T. S. Wee, Evelin Mihailov, Alexandra Karunas, Sergei Litvinov, Rita Khusainova, Natalya Ekomasova, Vita Akhmetova, Irina Khidiyatova, Damir Marjanović, Levon Yepiskoposyan, Doron M. Behar, Elena Balanovska, Andres Metspalu, Miroslava Derenko, Boris Malyarchuk, Mikhail Voevoda, Sardana A. Fedorova, Ludmila P. Osipova, Marta Mirazón Lahr, Pascale Gerbault, Matthew Leavesley, Andrea Bamberg Migliano, Michael Petraglia, Oleg Balanovsky, Elza K. Khusnutdinova, Ene Metspalu, Mark G. Thomas, Andrea Manica, Rasmus Nielsen, Richard Villems, Eske Willerslev, Toomas Kivisild and Mait Metspalu

De novo assembly and phasing of a Korean human genome pp. 243-247

Jeong-Sun Seo, Arang Rhie, Junsoo Kim, Sangjin Lee, Min-Hwan Sohn, Chang-Uk Kim, Alex Hastie, Han Cao, Ji-Young Yun, Jihye Kim, Junho Kuk, Gun Hwa Park, Juhyeok Kim, Hanna Ryu, Jongbum Kim, Mira Roh, Jeonghun Baek, Michael W. Hunkapiller, Jonas Korlach, Jong-Yeon Shin and Changhoon Kim

Genome-wide associations for birth weight and correlations with adult disease pp. 248-252

Momoko Horikoshi, Robin N. Beaumont, Felix R. Day, Nicole M. Warrington, Marjolein N. Kooijman, Juan Fernandez-Tajes, Bjarke Feenstra, Natalie R. van Zuydam, Kyle J. Gaulton, Niels Grarup, Jonathan P. Bradfield, David P. Strachan, Ruifang Li-Gao, Tarunveer S. Ahluwalia, Eskil Kreiner, Rico Rueedi, Leo-Pekka Lyytikäinen, Diana L. Cousminer, Ying Wu, Elisabeth Thiering, Carol A. Wang, Christian T. Have, Jouke-Jan Hottenga, Natalia Vilor-Tejedor, Peter K. Joshi, Eileen Tai Hui Boh, Ioanna Ntalla, Niina Pitkänen, Anubha Mahajan, Elisabeth M. van Leeuwen, Raimo Joro, Vasiliki Lagou, Michael Nodzenski, Louise A. Diver, Krina T. Zondervan, Mariona Bustamante, Pedro Marques-Vidal, Josep M. Mercader, Amanda J. Bennett, Nilufer Rahmioglu, Dale R. Nyholt, Ronald C. W. Ma, Claudia H. T. Tam, Wing Hung Tam, Santhi K. Ganesh, Frank J. A. van Rooij, Samuel E. Jones, Po-Ru Loh, Katherine S. Ruth, Marcus A. Tuke, Jessica Tyrrell, Andrew R. Wood, Hanieh Yaghootkar, Denise M. Scholtens, Lavinia Paternoster, Inga Prokopenko, Peter Kovacs, Mustafa Atalay, Sara M. Willems, Kalliope Panoutsopoulou, Xu Wang, Lisbeth Carstensen, Frank Geller, Katharina E. Schraut, Mario Murcia, Catharina E. M. van Beijsterveldt, Gonneke Willemsen, Emil V. R. Appel, Cilius E. Fonvig, Caecilie Trier, Carla M. T. Tiesler, Marie Standl, Zoltán Kutalik, Sílvia Bonàs-Guarch, David M. Hougaard, Friman Sánchez, David Torrents, Johannes Waage, Mads V. Hollegaard, Hugoline G. de Haan, Frits R. Rosendaal, Carolina Medina-Gomez, Susan M. Ring, Gibran Hemani, George McMahon, Neil R. Robertson, Christopher J. Groves, Claudia Langenberg, Jian’an Luan, Robert A. Scott, Jing Hua Zhao, Frank D. Mentch, Scott M. MacKenzie, Rebecca M. Reynolds, William L. Lowe, Anke Tönjes, Michael Stumvoll, Virpi Lindi, Timo A. Lakka, Cornelia M. van Duijn, Wieland Kiess, Antje Körner, Thorkild I. A. Sørensen, Harri Niinikoski, Katja Pahkala, Olli T. Raitakari, Eleftheria Zeggini, George V. Dedoussis, Yik-Ying Teo, Seang-Mei Saw, Mads Melbye, Harry Campbell, James F. Wilson, Martine Vrijheid, Eco J. C. N. de Geus, Dorret I. Boomsma, Haja N. Kadarmideen, Jens-Christian Holm, Torben Hansen, Sylvain Sebert, Andrew T. Hattersley, Lawrence J. Beilin, John P. Newnham, Craig E. Pennell, Joachim Heinrich, Linda S. Adair, Judith B. Borja, Karen L. Mohlke, Johan G. Eriksson, Elisabeth Widén, Mika Kähönen, Jorma S. Viikari, Terho Lehtimäki, Peter Vollenweider, Klaus Bønnelykke, Hans Bisgaard, Dennis O. Mook-Kanamori, Albert Hofman, Fernando Rivadeneira, André G. Uitterlinden, Charlotta Pisinger, Oluf Pedersen, Christine Power, Elina Hyppönen, Nicholas J. Wareham, Hakon Hakonarson, Eleanor Davies, Brian R. Walker, Vincent W. V. Jaddoe, Marjo-Riitta Järvelin, Struan F. A. Grant, Allan A. Vaag, Debbie A. Lawlor, Timothy M. Frayling, George Davey Smith, Andrew P. Morris, Ken K. Ong, Janine F. Felix, Nicholas J. Timpson, John R. B. Perry, David M. Evans, Mark I. McCarthy and Rachel M. Freathy

A cholinergic basal forebrain feeding circuit modulates appetite suppression pp. 253-256

Alexander M. Herman, Joshua Ortiz-Guzman, Mikhail Kochukov, Isabella Herman, Kathleen B. Quast, Jay M. Patel, Burak Tepe, Jeffrey C. Carlson, Kevin Ung, Jennifer Selever, Qingchun Tong and Benjamin R. Arenkiel

Evidence for a limit to human lifespan pp. 257-259

Xiao Dong, Brandon Milholland and Jan Vijg

Tissue-specific mutation accumulation in human adult stem cells during life pp. 260-264

Francis Blokzijl, Joep de Ligt, Myrthe Jager, Valentina Sasselli, Sophie Roerink, Nobuo Sasaki, Meritxell Huch, Sander Boymans, Ewart Kuijk, Pjotr Prins, Isaac J. Nijman, Inigo Martincorena, Michal Mokry, Caroline L. Wiegerinck, Sabine Middendorp, Toshiro Sato, Gerald Schwank, Edward E. S. Nieuwenhuis, Monique M. A. Verstegen, Luc J. W. van der Laan, Jeroen de Jonge, Jan N. M. IJzermans, Robert G. Vries, Marc van de Wetering, Michael R. Stratton, Hans Clevers, Edwin Cuppen and Ruben van Boxtel

Formation of new chromatin domains determines pathogenicity of genomic duplications pp. 265-269

Martin Franke, Daniel M. Ibrahim, Guillaume Andrey, Wibke Schwarzer, Verena Heinrich, Robert Schöpflin, Katerina Kraft, Rieke Kempfer, Ivana Jerković, Wing-Lee Chan, Malte Spielmann, Bernd Timmermann, Lars Wittler, Ingo Kurth, Paola Cambiaso, Orsetta Zuffardi, Gunnar Houge, Lindsay Lambie, Francesco Brancati, Ana Pombo, Martin Vingron, Francois Spitz and Stefan Mundlos

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection pp. 270-273

Alexandra East-Seletsky, Mitchell R. O’Connell, Spencer C. Knight, David Burstein, Jamie H. D. Cate, Robert Tjian and Jennifer A. Doudna

Correction: Corrigendum: Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells pp. 274-274

Morgan E. Carlson, Michael Hsu and Irina M. Conboy

Correction: Corrigendum: Distinct bone marrow blood vessels differentially regulate haematopoiesis pp. 274-274

Tomer Itkin, Shiri Gur-Cohen, Joel A. Spencer, Amir Schajnovitz, Saravana K. Ramasamy, Anjali P. Kusumbe, Guy Ledergor, Yookyung Jung, Idan Milo, Michael G. Poulos, Alexander Kalinkovich, Aya Ludin, Karin Golan, Eman Khatib, Anju Kumari, Orit Kollet, Guy Shakhar, Jason M. Butler, Shahin Rafii, Ralf H. Adams, David T. Scadden, Charles P. Lin and Tsvee Lapidot

Correction: Corrigendum: Concerted nucleophilic aromatic substitution with 19F− and 18F− pp. 274-274

Constanze N. Neumann, Jacob M. Hooker and Tobias Ritter

The dark side of the human genome pp. 275-277

Kelly Rae Chi

Volunteering: Pro bono science pp. 279-281

Amber Dance

Trade talk: Lab whiz pp. 281-281

Monya Baker

Galactic Empire Management Consulting: lessons learnt pp. 284-284

Aidan Doyle

2016, volume 538, articles 7623

Corporate culture has no place in academia pp. 7-7

Olof Hallonsten

Mission accomplished: Rosetta crashes into comet pp. 13-14

Elizabeth Gibney

US left with just one working fusion reactor — for now pp. 14-15

Jeff Tollefson

Syrian seed bank gets new home away from war pp. 16-17

Shaoni Bhattacharya

UK bioethicists eye designer babies and CRISPR cows pp. 17-17

Heidi Ledford

Medicine Nobel for research on how cells 'eat themselves' pp. 18-19

Richard Van Noorden and Heidi Ledford

Physics of 2D exotic matter wins Nobel pp. 18-18

Elizabeth Gibney and Davide Castelvecchi

Can we open the black box of AI? pp. 20-23

Davide Castelvecchi

Warning to forest destroyers: this scientist will catch you pp. 24-26

Gabriel Popkin

Clean up energy innovation pp. 27-29

Lucien Georgeson, Mark Maslin and Martyn Poessinouw

Renewables need a grand-challenge strategy pp. 30-30

Alan Bernstein, Edward H. Sargent, Alán Aspuru-Guzik, Richard Cogdell, Graham R. Fleming, Rienk Van Grondelle and Mario Molina

Theoretical physics: Windows on the weird pp. 32-33

Robert P. Crease

New in paperback pp. 34-34

Emily Banham

Climate science: Denialism deciphered pp. 34-35

Dave Reay

Memoir: Love and uncertainty pp. 35-36

Ann Finkbeiner

Theoretical physics: The emperor's new physics pp. 36-37

Richard Dawid

History: Addiction and the Reich pp. 38-39

Paul Weindling

Cybernetics: A mathematician of mind pp. 39-40

Manuel Blum

Monitoring: safeguarding the world's largest lake pp. 41-41

Maxim A. Timofeyev

Pollution: centralized pilot for e-waste processing pp. 41-41

Ya Tang

Open data: policies need policing pp. 41-41

Dominique Roche

Open data: curation is under-resourced pp. 41-41

Sabina Leonelli

Snakebites: costing recombinant antivenoms pp. 41-41

Andreas H. Laustsen

Donald Ainslie Henderson (1928–2016) pp. 42-42

Joel Breman

Cobalt gets in shape pp. 44-45

Michael Claeys

Acidic shield puts a chink in p53's armour pp. 45-46

Michelle C. Barton

Rebalancing the global methane budget pp. 46-48

Grant Allen

Search for neutrinoless double-β decay pp. 48-49

Giorgio Gratta

Climate and the peopling of the world pp. 49-50

Peter B. deMenocal and Chris Stringer

Circuit-based interrogation of sleep control pp. 51-59

Franz Weber and Yang Dan

Structural insight into the role of the Ton complex in energy transduction pp. 60-65

Hervé Celia, Nicholas Noinaj, Stanislav D. Zakharov, Enrica Bordignon, Istvan Botos, Monica Santamaria, Travis J. Barnard, William A. Cramer, Roland Lloubes and Susan K. Buchanan

X-ray structures define human P2X3 receptor gating cycle and antagonist action pp. 66-71

Steven E. Mansoor, Wei Lü, Wout Oosterheert, Mrinal Shekhar, Emad Tajkhorshid and Eric Gouaux

High-molecular-weight organic matter in the particles of comet 67P/Churyumov–Gerasimenko pp. 72-74

Nicolas Fray, Anaïs Bardyn, Hervé Cottin, Kathrin Altwegg, Donia Baklouti, Christelle Briois, Luigi Colangeli, Cécile Engrand, Henning Fischer, Albrecht Glasmachers, Eberhard Grün, Gerhard Haerendel, Hartmut Henkel, Herwig Höfner, Klaus Hornung, Elmar K. Jessberger, Andreas Koch, Harald Krüger, Yves Langevin, Harry Lehto, Kirsi Lehto, Léna Le Roy, Sihane Merouane, Paola Modica, François-Régis Orthous-Daunay, John Paquette, François Raulin, Jouni Rynö, Rita Schulz, Johan Silén, Sandra Siljeström, Wolfgang Steiger, Oliver Stenzel, Thomas Stephan, Laurent Thirkell, Roger Thomas, Klaus Torkar, Kurt Varmuza, Karl-Peter Wanczek, Boris Zaprudin, Jochen Kissel and Martin Hilchenbach

Nodal-chain metals pp. 75-78

Tomáš Bzdušek, QuanSheng Wu, Andreas Rüegg, Manfred Sigrist and Alexey A. Soluyanov

Surface patterning of nanoparticles with polymer patches pp. 79-83

Rachelle M. Choueiri, Elizabeth Galati, Héloïse Thérien-Aubin, Anna Klinkova, Egor M. Larin, Ana Querejeta-Fernández, Lili Han, Huolin L. Xin, Oleg Gang, Ekaterina B. Zhulina, Michael Rubinstein and Eugenia Kumacheva

Cobalt carbide nanoprisms for direct production of lower olefins from syngas pp. 84-87

Liangshu Zhong, Fei Yu, Yunlei An, Yonghui Zhao, Yuhan Sun, Zhengjia Li, Tiejun Lin, Yanjun Lin, Xingzhen Qi, Yuanyuan Dai, Lin Gu, Jinsong Hu, Shifeng Jin, Qun Shen and Hui Wang

Upward revision of global fossil fuel methane emissions based on isotope database pp. 88-91

Stefan Schwietzke, Owen A. Sherwood, Lori M. P. Bruhwiler, John B. Miller, Giuseppe Etiope, Edward J. Dlugokencky, Sylvia Englund Michel, Victoria A. Arling, Bruce H. Vaughn, James W. C. White and Pieter P. Tans

Late Pleistocene climate drivers of early human migration pp. 92-95

Axel Timmermann and Tobias Friedrich

A cross-modal genetic framework for the development and plasticity of sensory pathways pp. 96-98

Laura Frangeul, Gabrielle Pouchelon, Ludovic Telley, Sandrine Lefort, Christian Luscher and Denis Jabaudon

Autocrine BDNF–TrkB signalling within a single dendritic spine pp. 99-103

Stephen C. Harward, Nathan G. Hedrick, Charles E. Hall, Paula Parra-Bueno, Teresa A. Milner, Enhui Pan, Tal Laviv, Barbara L. Hempstead, Ryohei Yasuda and James O. McNamara

Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity pp. 104-108

Nathan G. Hedrick, Stephen C. Harward, Charles E. Hall, Hideji Murakoshi, James O. McNamara and Ryohei Yasuda

The lipolysis pathway sustains normal and transformed stem cells in adult Drosophila pp. 109-113

Shree Ram Singh, Xiankun Zeng, Jiangsha Zhao, Ying Liu, Gerald Hou, Hanhan Liu and Steven X. Hou

XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer pp. 114-117

Jimi Kim, Elizabeth McMillan, Hyun Seok Kim, Niranjan Venkateswaran, Gurbani Makkar, Jaime Rodriguez-Canales, Pamela Villalobos, Jasper Edgar Neggers, Saurabh Mendiratta, Shuguang Wei, Yosef Landesman, William Senapedis, Erkan Baloglu, Chi-Wan B. Chow, Robin E. Frink, Boning Gao, Michael Roth, John D. Minna, Dirk Daelemans, Ignacio I. Wistuba, Bruce A. Posner, Pier Paolo Scaglioni and Michael A. White

Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode pp. 118-122

Donglai Wang, Ning Kon, Gorka Lasso, Le Jiang, Wenchuan Leng, Wei-Guo Zhu, Jun Qin, Barry Honig and Wei Gu

Accessory subunits are integral for assembly and function of human mitochondrial complex I pp. 123-126

David A. Stroud, Elliot E. Surgenor, Luke E. Formosa, Boris Reljic, Ann E. Frazier, Marris G. Dibley, Laura D. Osellame, Tegan Stait, Traude H. Beilharz, David R. Thorburn, Agus Salim and Michael T. Ryan

Democratic databases: science on GitHub pp. 127-128

Jeffrey Perkel

Job applications: Under the covers pp. 129-130

Lesley Evans Ogden

A better letter pp. 131-131

Ingrid Eisenstadter

Simple things pp. 134-134

Rebecca Birch