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2025, volume 640, articles 8060

Author Correction: Traversable wormhole dynamics on a quantum processor pp. E32-E32

Daniel Jafferis, Alexander Zlokapa, Joseph D. Lykken, David K. Kolchmeyer, Samantha I. Davis, Nikolai Lauk, Hartmut Neven and Maria Spiropulu

Author Correction: Record sea surface temperature jump in 2023–2024 unlikely but not unexpected pp. E33-E33

Jens Terhaar, Friedrich A. Burger, Linus Vogt, Thomas L. Frölicher and Thomas F. Stocker

Author Correction: Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome pp. E34-E34

Guang-Hui Liu, Basam Z. Barkho, Sergio Ruiz, Dinh Diep, Jing Qu, Sheng-Lian Yang, Athanasia D. Panopoulos, Keiichiro Suzuki, Leo Kurian, Christopher Walsh, James Thompson, Stephanie Boue, Ho Lim Fung, Ignacio Sancho-Martinez, Kun Zhang, John Yates and Juan Carlos Izpisua Belmonte

Cancer vaccine momentum builds, but US funding cuts raise concerns pp. S53-S53

Bec Crew

mRNA technology helps reinvigorate the hunt for cancer vaccines pp. S54-S56

Bianca Nogrady

Clinical trials by the numbers pp. S58-S59

Benjamin Plackett

How AI is helping to boost cancer screening pp. S62-S64

Michael Eisenstein

Four rising stars at the forefront of cancer research pp. S68-S71

Felicity Nelson and Sandy Ong

Arctic researchers need to find ways to keep working together pp. 859-859

Torben R. Christensen

How Trump 2.0 is slashing NIH-backed research — in charts pp. 863-865

Max Kozlov and Chris Ryan

Five key climate and space projects on Trump’s chopping block pp. 865-867

Alexandra Witze, Dan Garisto and Jeff Tollefson

Radical approach to shrink particle colliders gains momentum pp. 867-868

Elizabeth Gibney

First global pandemic treaty agreed — without the US pp. 868-869

Celeste Biever

‘Mind blowing’: quantum computer untangles the mathematics of knots pp. 869-870

Davide Castelvecchi

Pig livers for people: US regulator greenlights first safety trial pp. 870-870

Rachel Fieldhouse

Three ways to cool Earth by pulling carbon from the sky pp. 872-874

Jeff Tollefson

Why politicians manipulate statistics — and what to do about it pp. 875-877

Ole J. Forsberg

How India rewrote the rules of space travel when it launched its first satellite pp. 877-879

Pranav Sharma

Neck deep in overdiagnosis: Books in brief pp. 879-879

Andrew Robinson

Richard Fortey obituary: palaeontologist, author and TV presenter who traced continents through fossils pp. 880-880

Derek E. G. Briggs

Defend scientific integrity and academic freedom pp. 881-881

Manolis Kogevinas, Giulia Pollarolo and Robert Barouki

The global assault on universities is an attack on democracy pp. 881-881

Salvador Santino Regilme

Europe must become a research epicentre as US system gets undermined pp. 881-881

Anna Rubartelli, Valeria Poli, Iain Mattaj and Roberto Sitia

Trade tariffs could worsen deforestation in South America pp. 881-881

Alexandre Antonelli, Caspar Chater, Bernardo Strassburg and Andrew Balmford

Lung signals drive cancer-associated blood clots pp. 883-884

Ana Luísa Correia

Shapeshifting origami material shrinks when twisted pp. 884-885

Philip Klocke and Larry L. Howell

Liver cancer recurrence predicted by immune-cell location and gene expression pp. 885-887

Christian M. Schürch

Lasso-shaped molecule is a new type of broad-spectrum antibiotic pp. 887-889

Lynn L. Silver

Pinpointing neurons that hinder cancer treatment pp. 889-890

Ihsan Ekin Demir and Elke Demir

A wetter ancient Arabia could have enabled easier intercontinental species dispersal pp. 890-891

Faysal Bibi

Carbon majors and the scientific case for climate liability pp. 893-901

Christopher W. Callahan and Justin S. Mankin

Evidence of star cluster migration and merger in dwarf galaxies pp. 902-906

Mélina Poulain, Rory Smith, Pierre-Alain Duc, Francine R. Marleau, Rebecca Habas, Patrick R. Durrell, Jérémy Fensch, Sungsoon Lim, Oliver Müller, Sanjaya Paudel and Rubén Sánchez-Janssen

Active energy compression of a laser-plasma electron beam pp. 907-910

P. Winkler, M. Trunk, L. Hübner, A. Martinez de la Ossa, S. Jalas, M. Kirchen, I. Agapov, S. A. Antipov, R. Brinkmann, T. Eichner, A. Ferran Pousa, T. Hülsenbusch, G. Palmer, M. Schnepp, K. Schubert, M. Thévenet, P. A. Walker, C. Werle, W. P. Leemans and A. R. Maier

Long-distance coherent quantum communications in deployed telecom networks pp. 911-917

Mirko Pittaluga, Yuen San Lo, Adam Brzosko, Robert I. Woodward, Davide Scalcon, Matthew S. Winnel, Thomas Roger, James F. Dynes, Kim A. Owen, Sergio Juárez, Piotr Rydlichowski, Domenico Vicinanza, Guy Roberts and Andrew J. Shields

Ultra-broadband optical amplification using nonlinear integrated waveguides pp. 918-923

Ping Zhao, Vijay Shekhawat, Marcello Girardi, Zonglong He, Victor Torres-Company and Peter A. Andrekson

Giant electrocaloric effect in high-polar-entropy perovskite oxides pp. 924-930

Feihong Du, Tiannan Yang, Hua Hao, Shangshu Li, Chenhang Xu, Tian Yao, Zhiwu Song, Jiahe Shen, Chenyun Bai, Ruhong Luo, Donglin Han, Qiang Li, Shanyu Zheng, Yingjing Zhang, Yezhan Lin, Zhenhua Ma, Haotian Chen, Chenyu Guo, Jiawang Feng, Shengyi Zhong, Ruilin Mai, Guodong Hou, Haixin Qiu, Meng Xie, Xin Chen, Yakun Yuan, Dong Qian, Dao Xiang, Xuefeng Chen, Zhengqian Fu, Genshui Wang, Hanxing Liu, Jiangping Chen, Guang Meng, Xiangyang Zhu, Long-Qing Chen, Shujun Zhang and Xiaoshi Qian

Modular chiral origami metamaterials pp. 931-940

Tuo Zhao, Xiangxin Dang, Konstantinos Manos, Shixi Zang, Jyotirmoy Mandal, Minjie Chen and Glaucio H. Paulino

Negative thermal expansion and oxygen-redox electrochemistry pp. 941-946

Bao Qiu, Yuhuan Zhou, Haoyan Liang, Minghao Zhang, Kexin Gu, Tao Zeng, Zhou Zhou, Wen Wen, Ping Miao, Lunhua He, Yinguo Xiao, Sven Burke, Zhaoping Liu and Ying Shirley Meng

Transforming ceria into 2D clusters enhances catalytic activity pp. 947-953

Konstantin Khivantsev, Hien Pham, Mark H. Engelhard, Hristiyan A. Aleksandrov, Libor Kovarik, Mark Bowden, Xiaohong Shari Li, Jinshu Tian, Iskra Z. Koleva, Inhak Song, Wenda Hu, Xinyi Wei, Yipeng Sun, Pascaline Tran, Trent R. Graham, Dong Jiang, David P. Dean, Christian J. Breckner, Jeffrey T. Miller, Georgi N. Vayssilov, János Szanyi, Abhaya Datye and Yong Wang

Recurrent humid phases in Arabia over the past 8 million years pp. 954-961

Monika Markowska, Hubert B. Vonhof, Huw S. Groucutt, Paul S. Breeze, Nick Drake, Mathew Stewart, Richard Albert, Eric Andrieux, James Blinkhorn, Nicole Boivin, Alexander Budsky, Richard Clark-Wilson, Dominik Fleitmann, Axel Gerdes, Ashley N. Martin, Alfredo Martínez-García, Samuel L. Nicholson, Gilbert J. Price, Eleanor M. L. Scerri, Denis Scholz, Nils Vanwezer, Michael Weber, Abdullah M. Alsharekh, Abdul Aziz Al Omari, Yahya S. A. Al-Mufarreh, Faisal Al-Jibreen, Mesfer Alqahtani, Mahmoud Al-Shanti, Iyad Zalmout, Michael D. Petraglia and Gerald H. Haug

A sharp volatile-rich cap to the Yellowstone magmatic system pp. 962-966

Chenglong Duan, Wenkai Song, Brandon Schmandt, Jamie Farrell, David Lumley, Tobias Fischer, Lindsay Lowe Worthington and Fan-Chi Lin

Latitudinal scaling of aggregation with abundance and coexistence in forests pp. 967-973

Thorsten Wiegand, Xugao Wang, Samuel M. Fischer, Nathan J. B. Kraft, Norman A. Bourg, Warren Y. Brockelman, Guanghong Cao, Min Cao, Wirong Chanthorn, Chengjin Chu, Stuart Davies, Sisira Ediriweera, C. V. Savitri Gunatilleke, I. A. U. Nimal Gunatilleke, Zhanqing Hao, Robert Howe, Mingxi Jiang, Guangze Jin, W. John Kress, Buhang Li, Juyu Lian, Luxiang Lin, Feng Liu, Keping Ma, William McShea, Xiangcheng Mi, Jonathan A. Myers, Anuttara Nathalang, David A. Orwig, Guochun Shen, Sheng-Hsin Su, I-Fang Sun, Xihua Wang, Amy Wolf, Enrong Yan, Wanhui Ye, Yan Zhu and Andreas Huth

A robustly rooted tree of eukaryotes reveals their excavate ancestry pp. 974-981

Kelsey Williamson, Laura Eme, Hector Baños, Charley G. P. McCarthy, Edward Susko, Ryoma Kamikawa, Russell J. S. Orr, Sergio A. Muñoz-Gómez, Bui Quang Minh, Alastair G. B. Simpson and Andrew J. Roger

Timing and trajectory of BCR::ABL1-driven chronic myeloid leukaemia pp. 982-990

Aleksandra E. Kamizela, Daniel Leongamornlert, Nicholas Williams, Xin Wang, Kudzai Nyamondo, Kevin Dawson, Michael Spencer Chapman, Jing Guo, Joe Lee, Karim Mane, Kate Milne, Anthony R. Green, Timothy Chevassut, Peter J. Campbell, Patrick T. Ellinor, Brian J. P. Huntly, E. Joanna Baxter and Jyoti Nangalia

Comparative characterization of human accelerated regions in neurons pp. 991-999

Xiekui Cui, Han Yang, Charles Cai, Cooper Beaman, Xiaoyu Yang, Hongjiang Liu, Xingjie Ren, Zachary Amador, Ian R. Jones, Kathleen C. Keough, Meng Zhang, Tyler Fair, Armen Abnousi, Shreya Mishra, Zhen Ye, Ming Hu, Alex A. Pollen, Katherine S. Pollard and Yin Shen

A hypothalamic circuit underlying the dynamic control of social homeostasis pp. 1000-1010

Ding Liu, Mostafizur Rahman, Autumn Johnson, Ryunosuke Amo, Iku Tsutsui-Kimura, Zuri A. Sullivan, Nicolai Pena, Mustafa Talay, Brandon L. Logeman, Samantha Finkbeiner, Lechen Qian, Seungwon Choi, Athena Capo-Battaglia, Ishmail Abdus-Saboor, David D. Ginty, Naoshige Uchida, Mitsuko Watabe-Uchida and Catherine Dulac

TIR1-produced cAMP as a second messenger in transcriptional auxin signalling pp. 1011-1016

Huihuang Chen, Linlin Qi, Minxia Zou, Mengting Lu, Mateusz Kwiatkowski, Yuanrong Pei, Krzysztof Jaworski and Jiří Friml

Pathogenesis of bovine H5N1 clade 2.3.4.4b infection in macaques pp. 1017-1021

Kyle Rosenke, Amanda Griffin, Franziska Kaiser, Ekaterina Altynova, Reshma Mukesh, Trenton Bushmaker, Meaghan Flagg, Thomas Tipih, Kerry Goldin, Arthur Wickenhagen, Brandi N. Williamson, Shane Gallogly, Shanna S. Leventhal, Tessa Lutterman, Atsushi Okumura, Matthew C. Lewis, Kishore Kanakabandi, Craig Martens, Kwe C. Yinda, Deepashri Rao, Brian J. Smith, Carl Shaia, Greg Saturday, Patrick Hanley, Neeltje Doremalen, Emmie Wit, Vincent J. Munster and Heinz Feldmann

A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome pp. 1022-1030

Manoj Jangra, Dmitrii Y. Travin, Elena V. Aleksandrova, Manpreet Kaur, Lena Darwish, Kalinka Koteva, Dorota Klepacki, Wenliang Wang, Maya Tiffany, Akosiererem Sokaribo, Brian K. Coombes, Nora Vázquez-Laslop, Yury S. Polikanov, Alexander S. Mankin and Gerard D. Wright

Spatial immune scoring system predicts hepatocellular carcinoma recurrence pp. 1031-1041

Gengjie Jia, Peiqi He, Tianli Dai, Denise Goh, Jiabei Wang, Mengyuan Sun, Felicia Wee, Fuling Li, Jeffrey Chun Tatt Lim, Shuxia Hao, Yao Liu, Tony Kiat Hon Lim, Nye-Thane Ngo, Qingping Tao, Wei Wang, Ahitsham Umar, Björn Nashan, Yongchang Zhang, Chen Ding, Joe Yeong, Lianxin Liu and Cheng Sun

Characterization of single neurons reprogrammed by pancreatic cancer pp. 1042-1051

Vera Thiel, Simon Renders, Jasper Panten, Nicolas Dross, Katharina Bauer, Daniel Azorin, Vanessa Henriques, Vanessa Vogel, Corinna Klein, Aino-Maija Leppä, Isabel Barriuso Ortega, Jonas Schwickert, Iordanis Ourailidis, Julian Mochayedi, Jan-Philipp Mallm, Carsten Müller-Tidow, Hannah Monyer, John Neoptolemos, Thilo Hackert, Oliver Stegle, Duncan T. Odom, Rienk Offringa, Albrecht Stenzinger, Frank Winkler, Martin Sprick and Andreas Trumpp

Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity pp. 1052-1061

Jie Yang, Yumi Yamashita-Kanemaru, Benjamin I. Morris, Annalisa Contursi, Daniel Trajkovski, Jingru Xu, Ilinca Patrascan, Jayme Benson, Alexander C. Evans, Alberto G. Conti, Aws Al-Deka, Layla Dahmani, Adnan Avdic-Belltheus, Baojie Zhang, Hanneke Okkenhaug, Sarah K. Whiteside, Charlotte J. Imianowski, Alexander J. Wesolowski, Louise V. Webb, Simone Puccio, Stefania Tacconelli, Annalisa Bruno, Sara Berardino, Alessandra Michele, Heidi C. E. Welch, I-Shing Yu, Shu-Wha Lin, Suman Mitra, Enrico Lugli, Louise Weyden, Klaus Okkenhaug, Kourosh Saeb-Parsy, Paola Patrignani, David J. Adams and Rahul Roychoudhuri

VDAC2 loss elicits tumour destruction and inflammation for cancer therapy pp. 1062-1071

Sujing Yuan, Renqiang Sun, Hao Shi, Nicole M. Chapman, Haoran Hu, Cliff Guy, Sherri Rankin, Anil Kc, Gustavo Palacios, Xiaoxi Meng, Xiang Sun, Peipei Zhou, Xiaoyang Yang, Stephen Gottschalk and Hongbo Chi

Programs, origins and immunomodulatory functions of myeloid cells in glioma pp. 1072-1082

Tyler E. Miller, Chadi A. El Farran, Charles P. Couturier, Zeyu Chen, Joshua P. D’Antonio, Julia Verga, Martin A. Villanueva, L. Nicolas Gonzalez Castro, Yuzhou Evelyn Tong, Tariq Al Saadi, Andrew N. Chiocca, Yuanyuan Zhang, David S. Fischer, Dieter Henrik Heiland, Jennifer L. Guerriero, Kevin Petrecca, Mario L. Suva, Alex K. Shalek and Bradley E. Bernstein

Evolutionary fingerprints of epithelial-to-mesenchymal transition pp. 1083-1092

Luigi Perelli, Li Zhang, Sarah Mangiameli, Francesca Giannese, Krishnan K. Mahadevan, Fuduan Peng, Francesca Citron, Hania Khan, Courtney Le, Enrico Gurreri, Federica Carbone, Andrew J. C. Russell, Melinda Soeung, Truong Nguyen Anh Lam, Sebastian Lundgren, Sujay Marisetty, Cihui Zhu, Desiree Catania, Alaa M. T. Mohamed, Ningping Feng, Jithesh Jose Augustine, Alessandro Sgambato, Giampaolo Tortora, Giulio F. Draetta, Giovanni Tonon, Andrew Futreal, Virginia Giuliani, Alessandro Carugo, Andrea Viale, Michael P. Kim, Timothy P. Heffernan, Linghua Wang, Raghu Kalluri, Davide Cittaro, Fei Chen and Giannicola Genovese

Comprehensive interrogation of synthetic lethality in the DNA damage response pp. 1093-1102

John Fielden, Sebastian M. Siegner, Danielle N. Gallagher, Markus S. Schröder, Maria Rosaria Dello Stritto, Simon Lam, Lena Kobel, Moritz F. Schlapansky, Stephen P. Jackson, Petr Cejka, Marco Jost and Jacob E. Corn

BRCA2 prevents PARPi-mediated PARP1 retention to protect RAD51 filaments pp. 1103-1111

Sudipta Lahiri, George Hamilton, Gemma Moore, Liana Goehring, Tony T. Huang, Ryan B. Jensen and Eli Rothenberg

Norway set to scrap mandatory language training for foreign postdocs and PhD students pp. 1113-1114

Linda Nordling

Showing ‘ability’ in ‘disability’ — how I mastered interviews while using a wheelchair pp. 1114-1115

Emilia Krok

Which programming language should I use? A guide for early-career researchers pp. 1116-1117

Jeffrey M. Perkel

Sowing solutions: my quest to save Kenya’s maize from a devastating invader pp. 1120-1120

Linda Nordling

2025, volume 640, articles 8059

Reframe perspectives on Alzheimer’s disease pp. S1-S1

Richard Hodson

Alzheimer’s disease: highlights from research pp. S2-S3

Liam Drew

The future of Alzheimer’s treatment pp. S4-S6

Simon Makin

The unusual genetic inheritance that could change Alzheimer’s treatment pp. S7-S7

Laura Vargas-Parada

Do infections have a role in Alzheimer’s disease? pp. S8-S10

Michael Eisenstein

Natively expressed AcrIII-1 does not function as an anti-CRISPR protein pp. E8-E14

Laura Martínez-Alvarez, Dominic Stickel, Andrea Salegi-Díez, Yuvaraj Bhoobalan-Chitty, Wen Zhong Shen and Xu Peng

Faster, cheaper, better: the rise of blood tests for Alzheimer’s pp. S11-S13

Elie Dolgin

Why women experience Alzheimer’s disease differently from men pp. S14-S17

Katherine Bourzac

Reply to: Natively expressed AcrIII-1 does not function as an anti-CRISPR protein pp. E15-E17

Januka S. Athukoralage, Stephen A. McMahon, Changyi Zhang, Sabine Grüschow, Shirley Graham, Mart Krupovic, Rachel J. Whitaker, Tracey M. Gloster and Malcolm F. White

Bovine H5N1 binds poorly to human-type sialic acid receptors pp. E18-E20

Jefferson J. S. Santos, Shengyang Wang, Ryan McBride, Lorin Adams, Ruth Harvey, Yan Zhao, Antoni G. Wrobel, Steven Gamblin, John Skehel, Nicola S. Lewis, James C. Paulson and Scott E. Hensley

Receptor-binding specificity of a bovine influenza A virus pp. E21-E27

Pradeep Chopra, Sean D. Ray, Caroline K. Page, Justin D. Shepard, Ahmed Kandeil, Trushar Jeevan, Andrew S. Bowman, Ali H. Ellebedy, Richard J. Webby, Robert P. Vries, S. Mark Tompkins and Geert-Jan Boons

A. J. Eisfeld et al. reply pp. E28-E29

Amie J. Eisfeld, Asim Biswas, Lizheng Guan, Chunyang Gu, Tadashi Maemura, Sanja Trifkovic, Tong Wang, Lavanya Babujee, Randall Dahn, Peter J. Halfmann, Tera Barnhardt, Gabriele Neumann, Yasuo Suzuki, Alexis Thompson, Amy K. Swinford, Kiril M. Dimitrov, Keith Poulsen and Yoshihiro Kawaoka

Author Correction: Isoprene nitrates drive new particle formation in Amazon’s upper troposphere pp. E30-E30

Joachim Curtius, Martin Heinritzi, Lisa J. Beck, Mira L. Pöhlker, Nidhi Tripathi, Bianca E. Krumm, Philip Holzbeck, Clara M. Nussbaumer, Lianet Hernández Pardo, Thomas Klimach, Konstantinos Barmpounis, Simone T. Andersen, Roman Bardakov, Birger Bohn, Micael A. Cecchini, Jean-Pierre Chaboureau, Thibaut Dauhut, Dirk Dienhart, Raphael Dörich, Achim Edtbauer, Andreas Giez, Antonia Hartmann, Bruna A. Holanda, Philipp Joppe, Katharina Kaiser, Timo Keber, Hannah Klebach, Ovid O. Krüger, Andreas Kürten, Christian Mallaun, Daniel Marno, Monica Martinez, Carolina Monteiro, Carolina Nelson, Linda Ort, Subha S. Raj, Sarah Richter, Akima Ringsdorf, Fabio Rocha, Mario Simon, Sreedev Sreekumar, Anywhere Tsokankunku, Gabriela R. Unfer, Isabella D. Valenti, Nijing Wang, Andreas Zahn, Marcel Zauner-Wieczorek, Rachel I. Albrecht, Meinrat O. Andreae, Paulo Artaxo, John N. Crowley, Horst Fischer, Hartwig Harder, Dirceu L. Herdies, Luiz A. T. Machado, Christopher Pöhlker, Ulrich Pöschl, Anna Possner, Andrea Pozzer, Johannes Schneider, Jonathan Williams and Jos Lelieveld

Author Correction: Controlled patterning of crystalline domains by frontal polymerization pp. E31-E31

Justine E. Paul, Yuan Gao, Yoo Kyung Go, Luis E. Rodriguez Koett, Anisha Sharma, Manxin Chen, Jacob J. Lessard, Tolga Topkaya, Cecilia Leal, Jeffrey S. Moore, Philippe H. Geubelle and Nancy R. Sottos

Meet the researchers pioneering Spanish climate solutions pp. S49-S51

Nikki Forrester

The fight to keep big tech in check: digital researchers are in ‘David and Goliath’ battle pp. 571-571

Amy Orben

Don’t believe the hype — quantum tech can’t yet solve real-world problems pp. 572-572

Joan Arrow

An animal source of mpox emerges — and it’s a squirrel pp. 575-576

Jane Qiu

Does US science have a future in Antarctica? Trump cuts threaten to cancel fieldwork and more pp. 576-577

Alexandra Witze

Will AI improve your life? Here’s what 4,000 researchers think pp. 577-578

Fred Schwaller

A mental-health crisis plagues PhDs — these evidence-led initiatives offer help pp. 579-580

Fred Schwaller

Obesity-drug pioneers and 13,508 physicists win US$3-million Breakthrough Prizes pp. 580-581

Zeeya Merali

NSF slashes prestigious PhD fellowship awards by half pp. 581-582

Dan Garisto

What makes us human? Milestone ape genomes promise clues pp. 582-582

Humberto Basilio

Japan’s big bet on stem-cell therapies might soon pay off with medical breakthroughs pp. 584-587

Smriti Mallapaty

Exclusive: the most-cited papers of the twenty-first century pp. 588-592

Helen Pearson, Heidi Ledford, Matthew Hutson and Richard Van Noorden

These are the most-cited research papers of all time pp. 591-591

Richard Van Noorden

Science’s golden oldies: the decades-old research papers still heavily cited today pp. 593-594

Richard Van Noorden

The dangerous fantasies driving the quest for super-intelligent AI pp. 595-596

Jaron Lanier

‘I’m touching space’: the fascinating insights meteorites can bring us pp. 597-598

Sara Russell

How the United States became a science superpower — and how quickly it could crumble pp. 599-601

Steve Blank

Africa CDC must become financially independent pp. 602-602

Nelson Aghogho Evaborhene, Jessica Oga and Echezona Udokanma

Scientists must regain trust pp. 602-602

Jonas De keersmaecker and Jay J. Van Bavel

Discussions of technologies’ societal impacts are still too limited pp. 602-602

Sparky Mitra

Ensuring that conferences are inclusive requires diverse organizers pp. 602-602

Jeremiah Joven Joaquin and Hazel T. Biana

Tiger turnaround as populations grow in India pp. 603-604

William F. Laurance and Uma Ramakrishnan

Docking stations in porous crystals unlock elusive molecular structures pp. 604-605

Hongyi Xu

New antifungal breaks the mould pp. 606-607

Arun Maji and Martin D. Burke

Live-cell super-resolution microscopy reveals how molecules enter and exit the nucleus pp. 607-608

Bernd Rieger and Enya S. Berrevoets

SWOT satellite provides a finer view of climate-driving ocean dynamics pp. 609-610

Elisa Carli

Biodiversity declines across fragmented forests pp. 610-611

Robert J. Fletcher

The growing memristor industry pp. 613-622

Mario Lanza, Sebastian Pazos, Fernando Aguirre, Abu Sebastian, Manuel Gallo, Syed M. Alam, Sumio Ikegawa, J. Joshua Yang, Elisa Vianello, Meng-Fan Chang, Gabriel Molas, Ishai Naveh, Daniele Ielmini, Ming Liu and Juan B. Roldan

Towards multimodal foundation models in molecular cell biology pp. 623-633

Haotian Cui, Alejandro Tejada-Lapuerta, Maria Brbić, Julio Saez-Rodriguez, Simona Cristea, Hani Goodarzi, Mohammad Lotfollahi, Fabian J. Theis and Bo Wang

Near-field photon entanglement in total angular momentum pp. 634-640

Amit Kam, Shai Tsesses, Yigal Ilin, Kobi Cohen, Yaakov Lumer, Lior Fridman, Stav Lotan, Anatoly Patsyk, Liat Nemirovsky-Levy, Meir Orenstein, Mordechai Segev and Guy Bartal

Ambient-pressure superconductivity onset above 40 K in (La,Pr)3Ni2O7 films pp. 641-646

Guangdi Zhou, Wei Lv, Heng Wang, Zihao Nie, Yaqi Chen, Yueying Li, Haoliang Huang, Wei-Qiang Chen, Yu-Jie Sun, Qi-Kun Xue and Zhuoyu Chen

Mastering diverse control tasks through world models pp. 647-653

Danijar Hafner, Jurgis Pasukonis, Jimmy Ba and Timothy Lillicrap

A RISC-V 32-bit microprocessor based on two-dimensional semiconductors pp. 654-661

Mingrui Ao, Xiucheng Zhou, Xinjie Kong, Saifei Gou, Sifan Chen, Xiangqi Dong, Yuxuan Zhu, Qicheng Sun, Zhejia Zhang, Jinshu Zhang, Qiran Zhang, Yan Hu, Chuming Sheng, Kaixuan Wang, Shuiyuan Wang, Jing Wan, Jun Han, Wenzhong Bao and Peng Zhou

Observation of plastic ice VII by quasi-elastic neutron scattering pp. 662-667

Maria Rescigno, Alberto Toffano, Umbertoluca Ranieri, Leon Andriambariarijaona, Richard Gaal, Stefan Klotz, Michael Marek Koza, Jacques Ollivier, Fausto Martelli, John Russo, Francesco Sciortino, Jose Teixeira and Livia Eleonora Bove

Metal–support frontier orbital interactions in single-atom catalysis pp. 668-675

Xianxian Shi, Zhilin Wen, Qingqing Gu, Long Jiao, Hai-Long Jiang, Haifeng Lv, Hengwei Wang, Jiani Ding, Mason P. Lyons, Alvin Chang, Zhenxing Feng, Si Chen, Yue Lin, Xiaoyan Xu, Pengfei Du, Wenlong Xu, Mei Sun, Yin Li, Bing Yang, Tao Zhang, Xiaojun Wu and Junling Lu

Supramolecular docking structure determination of alkyl-bearing molecules pp. 676-682

Yitao Wu, Le Shi, Lei Xu, Jiale Ying, Xiaohe Miao, Bin Hua, Zhijie Chen, Jonathan L. Sessler and Feihe Huang

σ-Bond insertion reactions of two strained diradicaloids pp. 683-690

Arismel Tena Meza, Christina A. Rivera, Huiling Shao, Andrew V. Kelleghan, K. N. Houk and Neil K. Garg

Wide-swath satellite altimetry unveils global submesoscale ocean dynamics pp. 691-696

Matthew Archer, Jinbo Wang, Patrice Klein, Gerald Dibarboure and Lee-Lueng Fu

Seismic imaging of a basaltic Lesser Antilles slab from ancient tectonics pp. 697-701

Xusong Yang, Yujiang Xie, Catherine A. Rychert, Nicholas Harmon, Saskia Goes, Andreas Rietbrock and Lloyd Lynch

Species turnover does not rescue biodiversity in fragmented landscapes pp. 702-706

Thiago Gonçalves-Souza, Jonathan M. Chase, Nick M. Haddad, Maurício H. Vancine, Raphael K. Didham, Felipe L. P. Melo, Marcelo A. Aizen, Enrico Bernard, Adriano G. Chiarello, Deborah Faria, Heloise Gibb, Marcelo G. Lima, Luiz F. S. Magnago, Eduardo Mariano-Neto, André A. Nogueira, André Nemésio, Marcelo Passamani, Bruno X. Pinho, Larissa Rocha-Santos, Rodolpho C. Rodrigues, Nathalia Vieira Hissa Safar, Bráulio A. Santos, Alejandra Soto-Werschitz, Marcelo Tabarelli, Marcio Uehara-Prado, Heraldo L. Vasconcelos, Simone Vieira and Nathan J. Sanders

The earliest human face of Western Europe pp. 707-713

Rosa Huguet, Xosé Pedro Rodríguez-Álvarez, María Martinón-Torres, Josep Vallverdú, Juan Manuel López-García, Marina Lozano, Marcos Terradillos-Bernal, Isabel Expósito, Andreu Ollé, Elena Santos, Palmira Saladié, Arturo Lombera-Hermida, Elena Moreno-Ribas, Laura Martín-Francés, Ethel Allué, Carmen Núñez-Lahuerta, Jan Made, Julia Galán, Hugues-Alexandre Blain, Isabel Cáceres, Antonio Rodríguez-Hidalgo, Amèlia Bargalló, Marina Mosquera, Josep Maria Parés, Juan Marín, Antonio Pineda, David Lordkipanidze, Ann Margveslashvili, Juan Luis Arsuaga, Eudald Carbonell and José María Bermúdez de Castro

Integrated analysis of the complete sequence of a macaque genome pp. 714-721

Shilong Zhang, Ning Xu, Lianting Fu, Xiangyu Yang, Kaiyue Ma, Yamei Li, Zikun Yang, Zhengtong Li, Yu Feng, Xinrui Jiang, Junmin Han, Ruixing Hu, Lu Zhang, Da Lian, Luciana Gennaro, Annalisa Paparella, Fedor Ryabov, Dan Meng, Yaoxi He, Dongya Wu, Chentao Yang, Yuxiang Mao, Xinyan Bian, Yong Lu, Francesca Antonacci, Mario Ventura, Valery A. Shepelev, Karen H. Miga, Ivan A. Alexandrov, Glennis A. Logsdon, Adam M. Phillippy, Bing Su, Guojie Zhang, Evan E. Eichler, Qing Lu, Yongyong Shi, Qiang Sun and Yafei Mao

A dual-pathway architecture for stress to disrupt agency and promote habit pp. 722-731

Jacqueline R. Giovanniello, Natalie Paredes, Anna Wiener, Kathia Ramírez-Armenta, Chukwuebuka Oragwam, Hanniel O. Uwadia, Abigail L. Yu, Kayla Lim, Jenna S. Pimenta, Gabriela E. Vilchez, Gift Nnamdi, Alicia Wang, Megha Sehgal, Fernando MCV Reis, Ana C. Sias, Alcino J. Silva, Avishek Adhikari, Melissa Malvaez and Kate M. Wassum

Topological segregation of stress sensors along the gut crypt–villus axis pp. 732-742

Kouki K. Touhara, Nathan D. Rossen, Fei Deng, Joel Castro, Andrea M. Harrington, Tifany Chu, Sonia Garcia-Caraballo, Mariana Brizuela, Tracey O’Donnell, Jinhao Xu, Onur Cil, Stuart M. Brierley, Yulong Li and David Julius

A polyene macrolide targeting phospholipids in the fungal cell membrane pp. 743-751

Qisen Deng, Yinchuan Li, Wenyan He, Tao Chen, Nan Liu, Lingman Ma, Zhixia Qiu, Zhuo Shang and Zongqiang Wang

Hepatic stellate cells control liver zonation, size and functions via R-spondin 3 pp. 752-761

Atsushi Sugimoto, Yoshinobu Saito, Guanxiong Wang, Qiuyan Sun, Chuan Yin, Ki Hong Lee, Yana Geng, Presha Rajbhandari, Celine Hernandez, Marcella Steffani, Jingran Qie, Thomas Savage, Dhruv M. Goyal, Kevin C. Ray, Taruna V. Neelakantan, Deqi Yin, Johannes Melms, Brandon M. Lehrich, Tyler M. Yasaka, Silvia Liu, Michael Oertel, Tian Lan, Adrien Guillot, Moritz Peiseler, Aveline Filliol, Hiroaki Kanzaki, Naoto Fujiwara, Samhita Ravi, Benjamin Izar, Mario Brosch, Jochen Hampe, Helen Remotti, Josepmaria Argemi, Zhaoli Sun, Timothy J. Kendall, Yujin Hoshida, Frank Tacke, Jonathan A. Fallowfield, Storm K. Blockley-Powell, Rebecca A. Haeusler, Jonathan B. Steinman, Utpal B. Pajvani, Satdarshan P. Monga, Ramon Bataller, Mojgan Masoodi, Nicholas Arpaia, Youngmin A. Lee, Brent R. Stockwell, Hellmut G. Augustin and Robert F. Schwabe

TGFβ links EBV to multisystem inflammatory syndrome in children pp. 762-771

Carl Christoph Goetzke, Mona Massoud, Stefan Frischbutter, Gabriela Maria Guerra, Marta Ferreira-Gomes, Frederik Heinrich, Anne Sae Lim Stuckrad, Sebastian Wisniewski, Jan Robin Licha, Marina Bondareva, Lisa Ehlers, Samira Khaldi-Plassart, Etienne Javouhey, Sylvie Pons, Sophie Trouillet-Assant, Yasemin Ozsurekci, Yu Zhang, Maria Cecilia Poli, Valentina Discepolo, Andrea Lo Vecchio, Bengü Sahin, Murielle Verboom, Michael Hallensleben, Anja Isabelle Heuhsen, Camila Astudillo, Yazmin Espinosa, Maria Cecilia Vial Cox, Kerry Dobbs, Ottavia M. Delmonte, Gina A. Montealegre Sanchez, Mary Magliocco, Karyl Barron, Jeffrey Danielson, Lev Petrov, Nadine Unterwalder, Birgit Sawitzki, Mareen Matz, Katrin Lehmann, Alexander Gratopp, Horst Bernuth, Lisa-Marie Burkhardt, Niklas Wiese, Lena Peter, Michael Schmueck-Henneresse, Leila Amini, Marcus Maurer, Jobst Fridolin Roehmel, Benjamin E. Gewurz, Lael M. Yonker, Mario Witkowski, Andrey Kruglov, Marcus Alexander Mall, Helen C. Su, Seza Ozen, Andreas Radbruch, Alexandre Belot, Pawel Durek, Tilmann Kallinich and Mir-Farzin Mashreghi

An early precursor CD8+ T cell that adapts to acute or chronic viral infection pp. 772-781

Daniel T. McManus, Rajesh M. Valanparambil, Christopher B. Medina, Christopher D. Scharer, Donald J. McGuire, Ewelina Sobierajska, Yinghong Hu, Daniel Y. Chang, Andreas Wieland, Judong Lee, Tahseen H. Nasti, Masao Hashimoto, James L. Ross, Nataliya Prokhnevska, Maria A. Cardenas, Amanda L. Gill, Elisa C. Clark, Kathleen Abadie, Arjun J. Kumar, Jonathan Kaye, Byron B. Au-Yeung, Hao Yuan Kueh, Haydn T. Kissick and Rafi Ahmed

Precursors of exhausted T cells are pre-emptively formed in acute infection pp. 782-792

Talyn Chu, Ming Wu, Barbara Hoellbacher, Gustavo P. Almeida, Christine Wurmser, Jacqueline Berner, Lara V. Donhauser, Ann-Katrin Gerullis, Siran Lin, J. Diego Cepeda-Mayorga, Iman I. Kilb, Lukas Bongers, Fabio Toppeta, Philipp Strobl, Ben Youngblood, Anna M. Schulz, Alfred Zippelius, Percy A. Knolle, Matthias Heinig, Carl-Philipp Hackstein and Dietmar Zehn

HIV immune evasin Nef enhances allogeneic CAR T cell potency pp. 793-801

Karlo Perica, Ivan S. Kotchetkov, Jorge Mansilla-Soto, Fiona Ehrich, Kevin Herrera, Yuzhe Shi, Anton Dobrin, Mithat Gönen and Michel Sadelain

Nociceptive neurons promote gastric tumour progression via a CGRP–RAMP1 axis pp. 802-810

Xiaofei Zhi, Feijing Wu, Jin Qian, Yosuke Ochiai, Guodong Lian, Ermanno Malagola, Biyun Zheng, Ruhong Tu, Yi Zeng, Hiroki Kobayashi, Zhangchuan Xia, Ruizhi Wang, Yueqing Peng, Qiongyu Shi, Duan Chen, Sandra W. Ryeom and Timothy C. Wang

MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC pp. 811-820

Elena Fiorini, Antonia Malinova, Daniel Schreyer, Davide Pasini, Michele Bevere, Giorgia Alessio, Diego Rosa, Sabrina D’Agosto, Luca Azzolin, Salvatore Milite, Silvia Andreani, Francesca Lupo, Lisa Veghini, Sonia Grimaldi, Serena Pedron, Monica Castellucci, Craig Nourse, Roberto Salvia, Giuseppe Malleo, Andrea Ruzzenente, Alfredo Guglielmi, Michele Milella, Rita T. Lawlor, Claudio Luchini, Antonio Agostini, Carmine Carbone, Christian Pilarsky, Andrea Sottoriva, Aldo Scarpa, David A. Tuveson, Peter Bailey and Vincenzo Corbo

Overlapping nuclear import and export paths unveiled by two-colour MINFLUX pp. 821-827

Abhishek Sau, Sebastian Schnorrenberg, Ziqiang Huang, Debolina Bandyopadhyay, Ankith Sharma, Clara-Marie Gürth, Sandeep Dave and Siegfried M. Musser

Genome-coverage single-cell histone modifications for embryo lineage tracing pp. 828-839

Min Liu, Yanzhu Yue, Xubin Chen, Kexin Xian, Chao Dong, Ming Shi, Haiqing Xiong, Kang Tian, Yuzhe Li, Qiangfeng Cliff Zhang and Aibin He

Chanoclavine synthase operates by an NADPH-independent superoxide mechanism pp. 840-846

Chun-Chi Chen, Zhi-Pu Yu, Ziwei Liu, Yongpeng Yao, Peter-Leon Hagedoorn, Rob Alexander Schmitz, Lujia Yang, Lu Yu, Aokun Liu, Xiang Sheng, Hao Su, Yaqing Ma, Te Wang, Jian-Wen Huang, Lilan Zhang, Juzhang Yan, Jinping Bao, Chengsen Cui, Xian Li, Panpan Shen, Wuyuan Zhang, Jian Min, Chang-Yun Wang, Rey-Ting Guo and Shu-Shan Gao

Should I return to my home country after my PhD abroad? pp. 847-848

Dyna Rochmyaningsih

Understanding bones from the remote wilderness of Wyoming pp. 850-850

Alexia Austin

2025, volume 640, articles 8058

Author Correction: Spatially resolved multiomics of human cardiac niches pp. E4-E4

Kazumasa Kanemaru, James Cranley, Daniele Muraro, Antonio M. A. Miranda, Siew Yen Ho, Anna Wilbrey-Clark, Jan Patrick Pett, Krzysztof Polanski, Laura Richardson, Monika Litvinukova, Natsuhiko Kumasaka, Yue Qin, Zuzanna Jablonska, Claudia I. Semprich, Lukas Mach, Monika Dabrowska, Nathan Richoz, Liam Bolt, Lira Mamanova, Rakeshlal Kapuge, Sam N. Barnett, Shani Perera, Carlos Talavera-López, Ilaria Mulas, Krishnaa T. Mahbubani, Liz Tuck, Lu Wang, Margaret M. Huang, Martin Prete, Sophie Pritchard, John Dark, Kourosh Saeb-Parsy, Minal Patel, Menna R. Clatworthy, Norbert Hübner, Rasheda A. Chowdhury, Michela Noseda and Sarah A. Teichmann

Author Correction: Heritable polygenic editing: the next frontier in genomic medicine? pp. E5-E5

Peter M. Visscher, Christopher Gyngell, Loic Yengo and Julian Savulescu

Author Correction: AI models collapse when trained on recursively generated data pp. E6-E6

Ilia Shumailov, Zakhar Shumaylov, Yiren Zhao, Nicolas Papernot, Ross Anderson and Yarin Gal

Publisher Correction: A metagenomic ‘dark matter’ enzyme catalyses oxidative cellulose conversion pp. E7-E7

Clelton A. Santos, Mariana A. B. Morais, Fernanda Mandelli, Evandro A. Lima, Renan Y. Miyamoto, Paula M. R. Higasi, Evandro A. Araujo, Douglas A. A. Paixão, Joaquim M. Junior, Maria L. Motta, Rodrigo S. A. Streit, Luana G. Morão, Claudio B. C. Silva, Lucia D. Wolf, Cesar R. F. Terrasan, Nathalia R. Bulka, Jose A. Diogo, Felipe J. Fuzita, Felippe M. Colombari, Camila R. Santos, Priscila T. Rodrigues, Daiane B. Silva, Sacha Grisel, Juliana S. Bernardes, Nicolas Terrapon, Vincent Lombard, Antonio J. C. Filho, Bernard Henrissat, Bastien Bissaro, Jean-Guy Berrin, Gabriela F. Persinoti and Mario T. Murakami

Why more AI researchers should collaborate with governments pp. 289-289

Mohamed Ibrahim

‘Now is not the time for despair’ — how scientists can take a stand against political interference pp. 290-290

Fernando Tormos-Aponte

‘One of the darkest days’: NIH purges agency leadership amid mass lay-offs pp. 293-294

Max Kozlov

Can trauma from violence be genetically inherited? Scientists debate Syria refugee study pp. 294-295

Miryam Naddaf

Brain implant translates thoughts to speech in an instant pp. 295-296

Miryam Naddaf

Deadly Myanmar earthquake was probably a rare rupture, scientists say pp. 296-297

Alexandra Witze

AlphaFold is running out of data — so drug firms are building their own version pp. 297-298

Ewen Callaway

75% of US scientists who answered Nature poll consider leaving pp. 298-299

Alexandra Witze

Incredible close-up of colourful crab spiders — March’s best science images pp. 299-299

Emma Stoye

How Europe aims to woo US scientists and protect academic freedom pp. 300-300

David Matthews

Cells are swapping their mitochondria. What does this mean for our health? pp. 302-304

Gemma Conroy

The hunt for the next CRISPR: how warring microbes are inspiring new technology pp. 306-308

Amber Dance

The life aquatic: this board game lets you dip into marine ecology pp. 309-310

Angela Chuang and Orlando Schwery

Why an overreliance on AI-driven modelling is bad for science pp. 312-314

Arvind Narayanan and Sayash Kapoor

Science’s big problem is a loss of influence, not a loss of trust pp. 314-317

Heidi J. Larson and David M. Bersoff

Europe needs to step up on epidemic preparedness pp. 318-318

Jonathan Ewbank

The US is against the world on sustainable development pp. 318-318

Guillaume Lafortune and Jeffrey D. Sachs

Europe must grasp chance to become a scientific powerhouse pp. 318-318

Oskar MacGregor and Maurice Lamb

Countries must consider their global footprint when using natural resources pp. 318-318

Éva Plagányi

A map of neural signals and circuits traces the logic of brain computation pp. 319-321

Mariela D. Petkova and Gregor F. P. Schuhknecht

Skin wound healing measured remotely through molecular flux pp. 321-322

Kellen Chen and Geoffrey C. Gurtner

Mutations that accrue through life set the stage for stomach cancer pp. 322-323

Callum Oddy and Marnix Jansen

Photonic chips provide a processing boost for AI pp. 323-325

Anthony Rizzo

What is the best type of tree to use for forest restoration? pp. 325-326

Pieter A. Zuidema and Madelon Lohbeck

Bird brains help scientists to unveil the secrets of speech pp. 326-327

Joshua Neunuebel

Intersectional analysis for science and technology pp. 329-337

Mathias Wullum Nielsen, Elena Gissi, Shirin Heidari, Richard Horton, Kari C. Nadeau, Dorothy Ngila, Safiya Umoja Noble, Hee Young Paik, Girmaw Abebe Tadesse, Eddy Y. Zeng, James Zou and Londa Schiebinger

Acoustic modes in M67 cluster stars trace deepening convective envelopes pp. 338-342

Claudia Reyes, Dennis Stello, Joel Ong, Christopher Lindsay, Marc Hon and Timothy R. Bedding

Certified randomness using a trapped-ion quantum processor pp. 343-348

Minzhao Liu, Ruslan Shaydulin, Pradeep Niroula, Matthew DeCross, Shih-Han Hung, Wen Yu Kon, Enrique Cervero-Martín, Kaushik Chakraborty, Omar Amer, Scott Aaronson, Atithi Acharya, Yuri Alexeev, K. Jordan Berg, Shouvanik Chakrabarti, Florian J. Curchod, Joan M. Dreiling, Neal Erickson, Cameron Foltz, Michael Foss-Feig, David Hayes, Travis S. Humble, Niraj Kumar, Jeffrey Larson, Danylo Lykov, Michael Mills, Steven A. Moses, Brian Neyenhuis, Shaltiel Eloul, Peter Siegfried, James Walker, Charles Lim and Marco Pistoia

Unconventional magnons in collinear magnets dictated by spin space groups pp. 349-354

Xiaobing Chen, Yuntian Liu, Pengfei Liu, Yutong Yu, Jun Ren, Jiayu Li, Ao Zhang and Qihang Liu

Fluctuating magnetism and Pomeranchuk effect in multilayer graphene pp. 355-360

Ludwig Holleis, Tian Xie, Siyuan Xu, Haoxin Zhou, Caitlin L. Patterson, Archisman Panigrahi, Takashi Taniguchi, Kenji Watanabe, Leonid S. Levitov, Chenhao Jin, Erez Berg and Andrea F. Young

An integrated large-scale photonic accelerator with ultralow latency pp. 361-367

Shiyue Hua, Erwan Divita, Shanshan Yu, Bo Peng, Charles Roques-Carmes, Zhan Su, Zhang Chen, Yanfei Bai, Jinghui Zou, Yunpeng Zhu, Yelong Xu, Cheng-kuan Lu, Yuemiao Di, Hui Chen, Lushan Jiang, Lijie Wang, Longwu Ou, Chaohong Zhang, Junjie Chen, Wen Zhang, Hongyan Zhu, Weijun Kuang, Long Wang, Huaiyu Meng, Maurice Steinman and Yichen Shen

Universal photonic artificial intelligence acceleration pp. 368-374

Sufi R. Ahmed, Reza Baghdadi, Mikhail Bernadskiy, Nate Bowman, Ryan Braid, Jim Carr, Chen Chen, Pietro Ciccarella, Matthew Cole, John Cooke, Kishor Desai, Carlos Dorta, Jonathan Elmhurst, Bryce Gardiner, Elliot Greenwald, Shashank Gupta, Parry Husbands, Brian Jones, Anthony Kopa, Ho John Lee, Arulselvan Madhavan, Adam Mendrela, Nicholas Moore, Lakshmi Nair, Aditya Om, Subie Patel, Rutayan Patro, Rob Pellowski, Esha Radhakrishnani, Sandeep Sane, Nicholas Sarkis, Joe Stadolnik, Mykhailo Tymchenko, Gongyu Wang, Kurt Winikka, Alexandra Wleklinski, Josh Zelman, Richard Ho, Ritesh Jain, Ayon Basumallik, Darius Bunandar and Nicholas C. Harris

A non-contact wearable device for monitoring epidermal molecular flux pp. 375-383

Jaeho Shin, Joseph Woojin Song, Matthew Thomas Flavin, Seunghee Cho, Shupeng Li, Ansen Tan, Kyung Rok Pyun, Aaron G Huang, Huifeng Wang, Seongmin Jeong, Kenneth E. Madsen, Jacob Trueb, Mirae Kim, Katelynn Nguyen, Angela Yang, Yaching Hsu, Winnie Sung, Jiwon Lee, Sooyeol Phyo, Ji-Hoon Kim, Anthony Banks, Jan-Kai Chang, Amy S. Paller, Yonggang Huang, Guillermo A. Ameer and John A. Rogers

Deconstruction of rubber via C–H amination and aza-Cope rearrangement pp. 384-389

Sydney E. Towell, Maxim Ratushnyy, Lauren S. Cooke, Geoffrey M. Lewis and Aleksandr V. Zhukhovitskiy

Formation and composition of Earth’s Hadean protocrust pp. 390-394

Simon Turner, Bernard Wood, Tim Johnson, Craig O’Neill and Bernard Bourdon

Widespread slow growth of acquisitive tree species pp. 395-401

L. Augusto, R. Borelle, A. Boča, L. Bon, C. Orazio, A. Arias-González, M. R. Bakker, N. Gartzia-Bengoetxea, H. Auge, F. Bernier, A. Cantero, J. Cavender-Bares, A. H. Correia, A. Schrijver, J. J. Diez-Casero, N. Eisenhauer, M. N. Fotelli, G. Gâteblé, D. L. Godbold, M. Gomes-Caetano-Ferreira, M. J. Gundale, H. Jactel, J. Koricheva, M. Larsson, V. A. Laudicina, A. Legout, J. Martín-García, W. L. Mason, C. Meredieu, S. Mereu, R. A. Montgomery, B. Musch, B. Muys, E. Paillassa, A. Paquette, J. D. Parker, W. C. Parker, Q. Ponette, C. Reynolds, M. J. Rozados-Lorenzo, R. Ruiz-Peinado, X. Santesteban-Insausti, M. Scherer-Lorenzen, F. J. Silva-Pando, A. Smolander, G. Spyroglou, E. B. Teixeira-Barcelos, E. I. Vanguelova, K. Verheyen, L. Vesterdal and M. Charru

Humans in Africa’s wet tropical forests 150 thousand years ago pp. 402-407

Eslem Ben Arous, James A. Blinkhorn, Sarah Elliott, Christopher A. Kiahtipes, Charles D. N’zi, Mark D. Bateman, Mathieu Duval, Patrick Roberts, Robert Patalano, Alexander F. Blackwood, Khady Niang, Eugénie Affoua Kouamé, Edith Lebato, Emily Hallett, Jacopo N. Cerasoni, Erin Scott, Jana Ilgner, Maria Jesús Alonso Escarza, Francois Yodé Guédé and Eleanor M. L. Scerri

Leveraging a phased pangenome for haplotype design of hybrid potato pp. 408-417

Lin Cheng, Nan Wang, Zhigui Bao, Qian Zhou, Andrea Guarracino, Yuting Yang, Pei Wang, Zhiyang Zhang, Dié Tang, Pingxian Zhang, Yaoyao Wu, Yao Zhou, Yi Zheng, Yong Hu, Qun Lian, Zhaoxu Ma, Ludivine Lassois, Chunzhi Zhang, William J. Lucas, Erik Garrison, Nils Stein, Thomas Städler, Yongfeng Zhou and Sanwen Huang

The somatic mutation landscape of normal gastric epithelium pp. 418-426

Tim H. H. Coorens, Grace Collord, Hyungchul Jung, Yichen Wang, Luiza Moore, Yvette Hooks, Krishnaa Mahbubani, Simon Y. K. Law, Helen H. N. Yan, Siu Tsan Yuen, Kourosh Saeb-Parsy, Peter J. Campbell, Iñigo Martincorena, Suet Yi Leung and Michael R. Stratton

Convergent vocal representations in parrot and human forebrain motor networks pp. 427-434

Zetian Yang and Michael A. Long

Inhibitory specificity from a connectomic census of mouse visual cortex pp. 448-458

Casey M. Schneider-Mizell, Agnes L. Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Leila Elabbady, Clare Gamlin, Daniel Kapner, Sam Kinn, Gayathri Mahalingam, Sharmishtaa Seshamani, Shelby Suckow, Marc Takeno, Russel Torres, Wenjing Yin, Sven Dorkenwald, J. Alexander Bae, Manuel A. Castro, Akhilesh Halageri, Zhen Jia, Chris Jordan, Nico Kemnitz, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, William Silversmith, Nicholas L. Turner, William Wong, Jingpeng Wu, Jacob Reimer, Andreas S. Tolias, H. Sebastian Seung, R. Clay Reid, Forrest Collman and Nuno Maçarico Costa

Functional connectomics reveals general wiring rule in mouse visual cortex pp. 459-469

Zhuokun Ding, Paul G. Fahey, Stelios Papadopoulos, Eric Y. Wang, Brendan Celii, Christos Papadopoulos, Andersen Chang, Alexander B. Kunin, Dat Tran, Jiakun Fu, Zhiwei Ding, Saumil Patel, Lydia Ntanavara, Rachel Froebe, Kayla Ponder, Taliah Muhammad, J. Alexander Bae, Agnes L. Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Manuel A. Castro, Erick Cobos, Sven Dorkenwald, Leila Elabbady, Akhilesh Halageri, Zhen Jia, Chris Jordan, Dan Kapner, Nico Kemnitz, Sam Kinn, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Gayathri Mahalingam, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, Casey M. Schneider-Mizell, William Silversmith, Marc Takeno, Russel Torres, Nicholas L. Turner, William Wong, Jingpeng Wu, Wenjing Yin, Szi-chieh Yu, Dimitri Yatsenko, Emmanouil Froudarakis, Fabian Sinz, Krešimir Josić, Robert Rosenbaum, H. Sebastian Seung, Forrest Collman, Nuno Maçarico Costa, R. Clay Reid, Edgar Y. Walker, Xaq Pitkow, Jacob Reimer and Andreas S. Tolias

Foundation model of neural activity predicts response to new stimulus types pp. 470-477

Eric Y. Wang, Paul G. Fahey, Zhuokun Ding, Stelios Papadopoulos, Kayla Ponder, Marissa A. Weis, Andersen Chang, Taliah Muhammad, Saumil Patel, Zhiwei Ding, Dat Tran, Jiakun Fu, Casey M. Schneider-Mizell, R. Clay Reid, Forrest Collman, Nuno Maçarico Costa, Katrin Franke, Alexander S. Ecker, Jacob Reimer, Xaq Pitkow, Fabian H. Sinz and Andreas S. Tolias

Perisomatic ultrastructure efficiently classifies cells in mouse cortex pp. 478-486

Leila Elabbady, Sharmishtaa Seshamani, Shang Mu, Gayathri Mahalingam, Casey M. Schneider-Mizell, Agnes L. Bodor, J. Alexander Bae, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Manuel A. Castro, Sven Dorkenwald, Akhilesh Halageri, Zhen Jia, Chris Jordan, Dan Kapner, Nico Kemnitz, Sam Kinn, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Eric Mitchell, Shanka Subhra Mondal, Barak Nehoran, Sergiy Popovych, William Silversmith, Marc Takeno, Russel Torres, Nicholas L. Turner, William Wong, Jingpeng Wu, Wenjing Yin, Szi-chieh Yu, H. Sebastian Seung, R. Clay Reid, Nuno Maçarico Costa and Forrest Collman

NEURD offers automated proofreading and feature extraction for connectomics pp. 487-496

Brendan Celii, Stelios Papadopoulos, Zhuokun Ding, Paul G. Fahey, Eric Wang, Christos Papadopoulos, Alexander B. Kunin, Saumil Patel, J. Alexander Bae, Agnes L. Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Manuel A. Castro, Erick Cobos, Sven Dorkenwald, Leila Elabbady, Akhilesh Halageri, Zhen Jia, Chris Jordan, Dan Kapner, Nico Kemnitz, Sam Kinn, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Gayathri Mahalingam, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, Casey M. Schneider-Mizell, William Silversmith, Marc Takeno, Russel Torres, Nicholas L. Turner, William Wong, Jingpeng Wu, Szi-chieh Yu, Wenjing Yin, Daniel Xenes, Lindsey M. Kitchell, Patricia K. Rivlin, Victoria A. Rose, Caitlyn A. Bishop, Brock Wester, Emmanouil Froudarakis, Edgar Y. Walker, Fabian Sinz, H. Sebastian Seung, Forrest Collman, Nuno Maçarico Costa, R. Clay Reid, Xaq Pitkow, Andreas S. Tolias and Jacob Reimer

Connectomics of predicted Sst transcriptomic types in mouse visual cortex pp. 497-505

Clare R. Gamlin, Casey M. Schneider-Mizell, Matthew Mallory, Leila Elabbady, Nathan Gouwens, Grace Williams, Alice Mukora, Rachel Dalley, Agnes L. Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Emily Joyce, Daniel Kapner, Sam Kinn, Gayathri Mahalingam, Sharmishtaa Seshamani, Marc Takeno, Russel Torres, Wenjing Yin, Philip R. Nicovich, J. Alexander Bae, Manuel A. Castro, Sven Dorkenwald, Akhilesh Halageri, Zhen Jia, Chris Jordan, Nico Kemnitz, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, William Silversmith, Nicholas L. Turner, William Wong, Jingpeng Wu, Szi-chieh Yu, Jim Berg, Tim Jarsky, Brian Lee, H. Sebastian Seung, Hongkui Zeng, R. Clay Reid, Forrest Collman, Nuno Maçarico Costa and Staci A. Sorensen

A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein pp. 506-513

Ellen Damme, Pravien Abeywickrema, Yanting Yin, Jiexiong Xie, Sofie Jacobs, Mandeep Kaur Mann, Jordi Doijen, Robyn Miller, Madison Piassek, Simone Marsili, Murali Subramanian, Leah Gottlieb, Rana Abdelnabi, Michiel Gool, Nick Broeck, Ines Pauw, Annick Diels, Peter Vermeulen, Koen Temmerman, Trevor Scobey, Melissa Mattocks, Alexandra Schäfer, Dirk Jochmans, Steven Jonghe, Pieter Leyssen, Winston Chiu, Mayra Diosa Toro, Marleen Zwaagstra, Anouk A. Leijs, Heidi L. M. Gruyter, Christophe Buyck, Klaas Heede, Frank Jacobs, Christel Eynde, Laura Thijs, Valerie Raeymaekers, Seth Miller, Amanda Rosario, Johan Neyts, Danielle Peeters, Ralph S. Baric, Frank J. M. Kuppeveld, Eric J. Snijder, Martijn J. Hemert, Mario Monshouwer, Sujata Sharma, Ruxandra Draghia-Akli, Anil Koul and Marnix Loock

A coronavirus assembly inhibitor that targets the viral membrane protein pp. 514-523

Manon Laporte, Dirk Jochmans, Dorothée Bardiot, Lowiese Desmarets, Oliver J. Debski-Antoniak, Giulia Mizzon, Rana Abdelnabi, Pieter Leyssen, Winston Chiu, Zhikuan Zhang, Norimichi Nomura, Sandro Boland, Umeharu Ohto, Yannick Stahl, Jurgen Wuyts, Steven Jonghe, Annelies Stevaert, Martijn J. Hemert, Brenda W. Bontes, Patrick Wanningen, G. J. Mirjam Groenewold, Aneta Zegar, Katarzyna Owczarek, Sanjata Joshi, Mohamed Koukni, Philippe Arzel, Hugo Klaassen, Jean-Christophe Vanherck, Ilse Vandecaetsbeek, Niels Cremers, Kim Donckers, Thibault Francken, Tina Buyten, Jasper Rymenants, Joost Schepers, Krzysztof Pyrc, Rolf Hilgenfeld, Jean Dubuisson, Berend-Jan Bosch, Frank Kuppeveld, Cecilia Eydoux, Etienne Decroly, Bruno Canard, Lieve Naesens, Birgit Weynand, Eric J. Snijder, Sandrine Belouzard, Toshiyuki Shimizu, Ralf Bartenschlager, Daniel L. Hurdiss, Arnaud Marchand, Patrick Chaltin and Johan Neyts

Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses pp. 524-533

Juliette Lesbats, Aurélia Brillac, Julie A. Reisz, Parnika Mukherjee, Charlène Lhuissier, Mónica Fernández-Monreal, Jean-William Dupuy, Angèle Sequeira, Gaia Tioli, Celia De La Calle Arregui, Benoît Pinson, Daniel Wendisch, Benoît Rousseau, Alejo Efeyan, Leif Erik Sander, Angelo D’Alessandro and Johan Garaude

Cooperative nutrient scavenging is an evolutionary advantage in cancer pp. 534-542

Gizem Guzelsoy, Setiembre D. Elorza, Manon Ros, Logan T. Schachtner, Makiko Hayashi, Spencer Hobson-Gutierrez, Parker Rundstrom, Julia S. Brunner, Ray Pillai, William E. Walkowicz, Lydia W. S. Finley, Maxime Deforet, Thales Papagiannakopoulos and Carlos Carmona-Fontaine

Extensive mutual influences of SMC complexes shape 3D genome folding pp. 543-553

Han Zhao, Lirong Shu, Shiyi Qin, Fangxuan Lyu, Fuhai Liu, En Lin, Sijian Xia, Baiyue Wang, Manzhu Wang, Fengnian Shan, Yinzhi Lin, Lin Zhang, Yufei Gu, Gerd A. Blobel, Kai Huang and Haoyue Zhang

AI for research: the ultimate guide to choosing the right tool pp. 555-557

Amanda Heidt

Where do proteins go in cells? Next-generation methods map the molecules’ hidden lives pp. 556-560

Ariana Remmel

Studying seabirds with a cactus as a research assistant pp. 562-562

Ugo Mellone

2025, volume 640, articles 8057

Author Correction: B-cell-specific checkpoint molecules that regulate anti-tumour immunity pp. E1-E1

Lloyd Bod, Yoon-Chul Kye, Jingwen Shi, Elena Torlai Triglia, Alexandra Schnell, Johannes Fessler, Stephen M. Ostrowski, Max Y. Von-Franque, Juhi R. Kuchroo, Rocky M. Barilla, Sarah Zaghouani, Elena Christian, Toni Marie Delorey, Kanishka Mohib, Sheng Xiao, Nadine Slingerland, Christopher J. Giuliano, Orr Ashenberg, Zhaorong Li, David M. Rothstein, David E. Fisher, Orit Rozenblatt-Rosen, Arlene H. Sharpe, Francisco J. Quintana, Lionel Apetoh, Aviv Regev and Vijay K. Kuchroo

Author Correction: Endocytosis in the axon initial segment maintains neuronal polarity pp. E2-E2

Kelsie Eichel, Takeshi Uenaka, Vivek Belapurkar, Rui Lu, Shouqiang Cheng, Joseph S. Pak, Caitlin A. Taylor, Thomas C. Südhof, Robert Malenka, Marius Wernig, Engin Özkan, David Perrais and Kang Shen

‘Open source’ AI isn’t truly open — here’s how researchers can reclaim the term pp. 9-9

Stefano Maffulli

Superpowers want to control critical mineral supplies — local communities need a stronger say pp. 10-10

Rabah Arezki

‘Anxiety is palpable’: detention of researchers at US border spurs travel worries pp. 13-14

Heidi Ledford and Alexandra Witze

Meet ‘qudits’: more complex cousins of qubits boost quantum computing pp. 14-15

Davide Castelvecchi

Does sharing first authorship on a paper carry a penalty? What the research says pp. 15-16

Holly Else

Pregnancy’s true toll on the body: huge birth study paints most detailed picture yet pp. 16-17

Celeste Biever

Exclusive: NIH to cut grants for COVID research, documents reveal pp. 17-18

Max Kozlov

Paralysed man stands again after receiving ‘reprogrammed’ stem cells pp. 18-19

Smriti Mallapaty

New antibiotic that kills drug-resistant bacteria discovered in technician’s garden pp. 19-20

Smriti Mallapaty

Mathematician who reshaped theory of symmetry wins Abel Prize pp. 20-20

Davide Castelvecchi

How to get rid of toxic ‘forever chemical’ pollution pp. 22-24

XiaoZhi Lim

Do smartphones and social media really harm teens’ mental health? pp. 26-28

Helen Pearson

Style over substance? What birds’ mating behaviours reveal about sexual selection pp. 29-30

Tim Coulson

Six roadblocks to net zero — and how to get around them pp. 31-34

Lucas Joppa and Elizabeth Willmott

The full lethal impact of massive cuts to international food aid pp. 35-37

Saskia Osendarp, Marie Ruel, Emorn Udomkesmalee, Masresha Tessema and Lawrence Haddad

The global scientific community must keep studying LGBT+ health pp. 38-38

Cláudia C. Gonçalves, Lana J. Williams, Alison R. Yung and Ashleigh Lin

Action needed to mitigate effects of slashing USAID pp. 38-38

Zaheer Allam and Ali Cheshmehzangi

Minerals will shape future geopolitical order pp. 38-38

Mariusz Baranowski, Piotr Jabkowski and Daniel M. Kammen

China has already taken steps to reduce retractions of papers from its hospitals pp. 38-38

Gong Jie Zhang and Ya Bin Zhou

How the Atlantic jet stream has changed in 600 years — and what it means for weather pp. 39-40

Matthew P. Dannenberg and Erika K. Wise

The early origins of bone-tool manufacturing traditions by hominins 1.5 million years ago pp. 40-42

Marta Mirazón Lahr

Light wins uphill battle to solve enduring problem in organic synthesis pp. 42-44

Wenzheng Fan and Guosheng Liu

Genus-wide plant pangenome could inform next-generation crop design pp. 44-45

Nadia Kamal and Manuel Spannagl

Designer cannabinoids could be the key to pain relief without adverse effects pp. 45-46

Iain R. Greig and Ruth A. Ross

Microsatellite-based real-time quantum key distribution pp. 47-54

Yang Li, Wen-Qi Cai, Ji-Gang Ren, Chao-Ze Wang, Meng Yang, Liang Zhang, Hui-Ying Wu, Liang Chang, Jin-Cai Wu, Biao Jin, Hua-Jian Xue, Xue-Jiao Li, Hui Liu, Guang-Wen Yu, Xue-Ying Tao, Ting Chen, Chong-Fei Liu, Wen-Bin Luo, Jie Zhou, Hai-Lin Yong, Yu-Huai Li, Feng-Zhi Li, Cong Jiang, Hao-Ze Chen, Chao Wu, Xin-Hai Tong, Si-Jiang Xie, Fei Zhou, Wei-Yue Liu, Yaseera Ismail, Francesco Petruccione, Nai-Le Liu, Li Li, Feihu Xu, Yuan Cao, Juan Yin, Rong Shu, Xiang-Bin Wang, Qiang Zhang, Jian-Yu Wang, Sheng-Kai Liao, Cheng-Zhi Peng and Jian-Wei Pan

Cooper-pair density modulation state in an iron-based superconductor pp. 55-61

Lingyuan Kong, Michał Papaj, Hyunjin Kim, Yiran Zhang, Eli Baum, Hui Li, Kenji Watanabe, Takashi Taniguchi, Genda Gu, Patrick A. Lee and Stevan Nadj-Perge

Downscaling micro- and nano-perovskite LEDs pp. 62-68

Yaxiao Lian, Yaxin Wang, Yucai Yuan, Zhixiang Ren, Weidong Tang, Zhe Liu, Shiyu Xing, Kangyu Ji, Bo Yuan, Yichen Yang, Yuxiang Gao, Shiang Zhang, Ke Zhou, Gan Zhang, Samuel D. Stranks, Baodan Zhao and Dawei Di

Synaptic and neural behaviours in a standard silicon transistor pp. 69-76

Sebastian Pazos, Kaichen Zhu, Marco A. Villena, Osamah Alharbi, Wenwen Zheng, Yaqing Shen, Yue Yuan, Yue Ping and Mario Lanza

Millimetre-scale bioresorbable optoelectronic systems for electrotherapy pp. 77-86

Yamin Zhang, Eric Rytkin, Liangsong Zeng, Jong Uk Kim, Lichao Tang, Haohui Zhang, Aleksei Mikhailov, Kaiyu Zhao, Yue Wang, Li Ding, Xinyue Lu, Anastasia Lantsova, Elena Aprea, Gengming Jiang, Shupeng Li, Seung Gi Seo, Tong Wang, Jin Wang, Jiayang Liu, Jianyu Gu, Fei Liu, Keith Bailey, Yat Fung Larry Li, Amy Burrell, Anna Pfenniger, Andrey Ardashev, Tianyu Yang, Naijia Liu, Zengyao Lv, Nathan S. Purwanto, Yue Ying, Yinsheng Lu, Claire Hoepfner, Altynai Melisova, Jiarui Gong, Jinheon Jeong, Junhwan Choi, Alex Hou, Rachel Nolander, Wubin Bai, Sung Hun Jin, Zhenqiang Ma, John M. Torkelson, Yonggang Huang, Wei Ouyang, Rishi K. Arora, Igor R. Efimov and John A. Rogers

Water structure and electric fields at the interface of oil droplets pp. 87-93

Lixue Shi, R. Allen LaCour, Naixin Qian, Joseph P. Heindel, Xiaoqi Lang, Ruoqi Zhao, Teresa Head-Gordon and Wei Min

Catalytic allylation of native hexoses and pentoses in water with indium pp. 94-99

Tapas Adak, Travis Menard, Matthew Albritton, Federico Florit, Martin D. Burke, Klavs F. Jensen and Scott E. Denmark

Phosphate-enabled mechanochemical PFAS destruction for fluoride reuse pp. 100-106

Long Yang, Zijun Chen, Christopher A. Goult, Thomas Schlatzer, Robert S. Paton and Véronique Gouverneur

Photoinduced copper-catalysed deracemization of alkyl halides pp. 107-113

Feng Zhong, Renhe Li, Binh Khanh Mai, Peng Liu and Gregory C. Fu

Solidification of Earth’s mantle led inevitably to a basal magma ocean pp. 114-119

Charles-Édouard Boukaré, James Badro and Henri Samuel

Global engineering effects of soil invertebrates on ecosystem functions pp. 120-129

Donghao Wu, Enzai Du, Nico Eisenhauer, Jérome Mathieu and Chengjin Chu

Systematic bone tool production at 1.5 million years ago pp. 130-134

Ignacio Torre, Luc Doyon, Alfonso Benito-Calvo, Rafael Mora, Ipyana Mwakyoma, Jackson K. Njau, Renata F. Peters, Angeliki Theodoropoulou and Francesco d’Errico

Solanum pan-genetics reveals paralogues as contingencies in crop engineering pp. 135-145

Matthias Benoit, Katharine M. Jenike, James W. Satterlee, Srividya Ramakrishnan, Iacopo Gentile, Anat Hendelman, Michael J. Passalacqua, Hamsini Suresh, Hagai Shohat, Gina M. Robitaille, Blaine Fitzgerald, Michael Alonge, Xingang Wang, Ryan Santos, Jia He, Shujun Ou, Hezi Golan, Yumi Green, Kerry Swartwood, Nicholas G. Karavolias, Gina P. Sierra, Andres Orejuela, Federico Roda, Sara Goodwin, W. Richard McCombie, Elizabeth B. Kizito, Edeline Gagnon, Sandra Knapp, Tiina E. Särkinen, Amy Frary, Jesse Gillis, Joyce Eck, Michael C. Schatz and Zachary B. Lippman

A compendium of human gene functions derived from evolutionary modelling pp. 146-154

Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Anushya Muruganujan, Suzanna E. Lewis, Dustin Ebert, Tremayne Mushayahama and Paul D. Thomas

Global modules robustly emerge from local interactions and smooth gradients pp. 155-164

Mikail Khona, Sarthak Chandra and Ila Fiete

Learning produces an orthogonalized state machine in the hippocampus pp. 165-175

Weinan Sun, Johan Winnubst, Maanasa Natrajan, Chongxi Lai, Koichiro Kajikawa, Arco Bast, Michalis Michaelos, Rachel Gattoni, Carsen Stringer, Daniel Flickinger, James E. Fitzgerald and Nelson Spruston

Fine-scale patterns of SARS-CoV-2 spread from identical pathogen sequences pp. 176-185

Cécile Tran-Kiem, Miguel I. Paredes, Amanda C. Perofsky, Lauren A. Frisbie, Hong Xie, Kevin Kong, Amelia Weixler, Alexander L. Greninger, Pavitra Roychoudhury, JohnAric M. Peterson, Andrew Delgado, Holly Halstead, Drew MacKellar, Philip Dykema, Luis Gamboa, Chris D. Frazar, Erica Ryke, Jeremy Stone, David Reinhart, Lea Starita, Allison Thibodeau, Cory Yun, Frank Aragona, Allison Black, Cécile Viboud and Trevor Bedford

Ancient genomes reveal a deep history of Treponema pallidum in the Americas pp. 186-193

Rodrigo Barquera, T. Lesley Sitter, Casey L. Kirkpatrick, Darío A. Ramirez, Arthur Kocher, Maria A. Spyrou, Lourdes R. Couoh, Jorge A. Talavera-González, Mario Castro, Tanya Hunnius, Evelyn K. Guevara, W. Derek Hamilton, Patrick Roberts, Erin Scott, Mariana Fabra, Gabriela V. Peña, Aryel Pacheco, Mónica Rodriguez, Eugenio Aspillaga, Anthi Tiliakou, Elizabeth A. Nelson, Karen L. Giffin, Raffaela A. Bianco, Adam B. Rohrlach, María los Ángeles García Martínez, Fabiola A. Ballesteros Solís, Antti Sajantila, Shelley R. Saunders, Rodrigo Nores, Alexander Herbig, Johannes Krause and Kirsten I. Bos

A systems-level, semi-quantitative landscape of metabolic flux in C. elegans pp. 194-202

Hefei Zhang, Xuhang Li, L. Tenzin Tseyang, Gabrielle E. Giese, Hui Wang, Bo Yao, Jingyan Zhang, Rachel L. Neve, Elizabeth A. Shank, Jessica B. Spinelli, L. Safak Yilmaz and Albertha J. M. Walhout

Systems-level design principles of metabolic rewiring in an animal pp. 203-211

Xuhang Li, Hefei Zhang, Thomas Hodder, Wen Wang, Chad L. Myers, L. Safak Yilmaz and Albertha J. M. Walhout

Macrophages protect against sensory axon loss in peripheral neuropathy pp. 212-220

Sara Hakim, Aakanksha Jain, Stuart S. Adamson, Veselina Petrova, Jonathan Indajang, Hyoung Woo Kim, Riki Kawaguchi, Qing Wang, Elif S. Duran, Drew Nelson, Caitlin A. Greene, Jenae Rasmussen and Clifford J. Woolf

RUNX2 promotes fibrosis via an alveolar-to-pathological fibroblast transition pp. 221-230

Yinshan Fang, Sanny S. W. Chung, Le Xu, Chenyi Xue, Xue Liu, Dianhua Jiang, Rongbo Li, Yohei Korogi, Ke Yuan, Anjali Saqi, Hanina Hibshoosh, Yuefeng Huang, Chyuan-Sheng Lin, Tatsuya Tsukui, Dean Sheppard, Xin Sun and Jianwen Que

Crypt density and recruited enhancers underlie intestinal tumour initiation pp. 231-239

Liam Gaynor, Harshabad Singh, Guodong Tie, Krithika Badarinath, Shariq Madha, Andrew Mancini, Swarnabh Bhattacharya, Mikio Hoshino, Frederic J. Sauvage, Kazutaka Murata, Unmesh Jadhav and Ramesh A. Shivdasani

Endogenous DNA damage at sites of terminated transcripts pp. 240-248

Jingjing Liu, Jullian O. Perren, Cody M. Rogers, Sadeieh Nimer, Alice X. Wen, Jennifer A. Halliday, Devon M. Fitzgerald, Qian Mei, Ralf B. Nehring, Mary Crum, Stanislav G. Kozmin, Jun Xia, Matthew B. Cooke, Yin Zhai, David Bates, Lei Li, P. J. Hastings, Irina Artsimovitch, Christophe Herman, Patrick M. Sung, Kyle M. Miller and Susan M. Rosenberg

De novo design of transmembrane fluorescence-activating proteins pp. 249-257

Jingyi Zhu, Mingfu Liang, Ke Sun, Yu Wei, Ruiying Guo, Lijing Zhang, Junhui Shi, Dan Ma, Qi Hu, Gaoxingyu Huang and Peilong Lu

The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation pp. 258-264

James C. V. Stacey, Dominik Hrebík, Elizabeth Nand, Snehith Dyavari Shetty, Kun Qu, Marius Boicu, Maria Anders-Össwein, Pradeep D. Uchil, Robert A. Dick, Walther Mothes, Hans-Georg Kräusslich, Barbara Müller and John A. G. Briggs

A cryptic pocket in CB1 drives peripheral and functional selectivity pp. 265-273

Vipin Ashok Rangari, Evan S. O’Brien, Alexander S. Powers, Richard A. Slivicki, Zachariah Bertels, Kevin Appourchaux, Deniz Aydin, Nokomis Ramos-Gonzalez, Juliet Mwirigi, Li Lin, Elizaveta Mangutov, Briana L. Sobecks, Yaseen Awad-Agbaria, Manoj B. Uphade, Jhoan Aguilar, Teja Nikhil Peddada, Yuki Shiimura, Xi-Ping Huang, Jakayla Folarin-Hines, Maria Payne, Anirudh Kalathil, Balazs R. Varga, Brian K. Kobilka, Amynah A. Pradhan, Michael D. Cameron, Kaavya Krishna Kumar, Ron O. Dror, Robert W. Gereau and Susruta Majumdar

How to know whether a conference is right for you pp. 275-277

Christine Ro

Deep dive: How I use robots to survey coral reefs pp. 280-280

Nikki Forrester