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2025, volume 646, articles 8087

Carbon implications of wood harvesting and forest management pp. E18-E19

Brent Sohngen, Justin S. Baker, Alice Favero and Adam Daigneault

Reply to: Carbon implications of wood harvesting and forest management pp. E20-E23

Timothy D. Searchinger, Steven Berry and Liqing Peng

On anisotropy in cubic Cu2O photoelectrodes pp. E24-E25

Yuhao Fu and David J. Singh

Reply to: On anisotropy in cubic Cu2O photoelectrodes pp. E26-E27

Linfeng Pan, Linjie Dai, Oliver J. Burton, Lu Chen, Virgil Andrei, Youcheng Zhang, Dan Ren, Jinshui Cheng, Linxiao Wu, Kyle Frohna, Anna Abfalterer, Terry Chien-Jen Yang, Wenzhe Niu, Meng Xia, Stephan Hofmann, Paul J. Dyson, Erwin Reisner, Henning Sirringhaus, Jingshan Luo, Anders Hagfeldt, Michael Grätzel and Samuel D. Stranks

Author Correction: Crystal structure of heliorhodopsin pp. E28-E28

Wataru Shihoya, Keiichi Inoue, Manish Singh, Masae Konno, Shoko Hososhima, Keitaro Yamashita, Kento Ikeda, Akimitsu Higuchi, Tamaki Izume, Sae Okazaki, Masanori Hashimoto, Ritsu Mizutori, Sahoko Tomida, Yumeka Yamauchi, Rei Abe-Yoshizumi, Kota Katayama, Satoshi P. Tsunoda, Mikihiro Shibata, Yuji Furutani, Alina Pushkarev, Oded Béjà, Takayuki Uchihashi, Hideki Kandori and Osamu Nureki

Author Correction: Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy pp. E29-E30

Elisabeth Perez-Ruiz, Luna Minute, Itziar Otano, Maite Alvarez, Maria Carmen Ochoa, Virginia Belsue, Carlos de Andrea, Maria Esperanza Rodriguez-Ruiz, Jose Luis Perez-Gracia, Ivan Marquez-Rodas, Casilda Llacer, Martina Alvarez, Vanesa de Luque, Carmen Molina, Alvaro Teijeira, Pedro Berraondo and Ignacio Melero

Author Correction: Ribonucleotide incorporation into mitochondrial DNA drives inflammation pp. E31-E31

Amir Bahat, Dusanka Milenkovic, Eileen Cors, Mabel Barnett, Sadig Niftullayev, Athanasios Katsalifis, Marc Schwill, Petra Kirschner, Thomas MacVicar, Patrick Giavalisco, Louise Jenninger, Anders R. Clausen, Vincent Paupe, Julien Prudent, Nils-Göran Larsson, Manuel Rogg, Christoph Schell, Isabella Muylaert, Erik Larsson, Hendrik Nolte, Maria Falkenberg and Thomas Langer

Author Correction: EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells pp. E32-E32

Jianhua Li, Erick Lu, Tangsheng Yi and Jason G. Cyster

Publisher Correction: Psilocybin’s lasting action requires pyramidal cell types and 5-HT2A receptors pp. E33-E33

Ling-Xiao Shao, Clara Liao, Pasha A. Davoudian, Neil K. Savalia, Quan Jiang, Cassandra Wojtasiewicz, Diran Tan, Jack D. Nothnagel, Rong-Jian Liu, Samuel C. Woodburn, Olesia M. Bilash, Hail Kim, Alicia Che and Alex C. Kwan

How nanobots are accelerating cancer-targeting therapies pp. S39-S41

Amanda Heidt

We need a new Turing test to assess AI’s real-world knowledge pp. 1027-1027

Vinay K. Chaudhri

What now for the global plastics treaty? pp. 1028-1028

Maria Ivanova

Blood tests are now approved for Alzheimer’s: how accurate are they? pp. 1031-1032

Katie Kavanagh

What’s the cap on human energy expenditure? Elite athletes reveal ‘metabolic ceiling’ pp. 1032-1033

Mohana Basu

Surprise meteorite debris uncovered on Moon’s far side pp. 1033-1033

Jenna Ahart

How scientists are pushing back against Trump’s funding ‘deal’ for universities pp. 1034-1035

Dan Garisto, Alexandra Witze and Jenna Ahart

People with blindness can read again after retinal implant pp. 1035-1036

Liam Drew

Is academic research becoming too competitive? Nature examines the data pp. 1036-1037

Miryam Naddaf

The world’s first plastics treaty is in crisis: can it be salvaged? pp. 1038-1038

Katharine Sanderson

7 basic science discoveries that changed the world pp. 1040-1043

Michael Marshall

Plants have a secret language that scientists are only now starting to decipher pp. 1044-1046

Amber Dance

AI can supercharge inequality — unless the public learns to control it pp. 1048-1049

Cathy O’Neil

How do you know what I know you know? Steven Pinker on common knowledge pp. 1050-1051

David Adam

John Gurdon obituary: Biologist who made cloning possible pp. 1053-1053

Ron Laskey

Environmental treaties are paralysed — here’s how we can do better pp. 1054-1056

Rakhyun E. Kim and Peter Bridgewater

How to understand exoplanets — space scientists call on lab-based chemists to help pp. 1057-1059

Frank A. F. Winiberg, Laura Kreidberg, Julianne I. Moses, Carl J. Percival and Paul I. Palmer

Don’t overlook the plastic footprint of fireworks pp. 1060-1060

Kai Liu, Zongbo Shi, Yulan Zhang and Daoji Li

Treat children as citizen co-researchers in health technology pp. 1060-1060

Melike Şahinol

Ethics must keep pace with embryo research pp. 1060-1060

Tsutomu Sawai

Universities can harness AI to make learning intuitive pp. 1060-1060

Shuaiguo Wang

Ultrasound-driven artificial muscles can grasp, flex and swim pp. 1061-1062

Joseph Rufo and Tony Jun Huang

Distorted representations of age and gender are reflected in AI models pp. 1062-1063

Ana Macanovic

Early- and late-diagnosed autism are genetically distinct pp. 1064-1065

Elliot M. Tucker-Drob

To make water, exoplanets might just need some pressure pp. 1065-1067

Quentin Williams

Wired for growth: neuron–tumour signalling in the lung and brain increases growth of a hard-to-treat cancer pp. 1067-1068

Abbie S. Ireland and Trudy G. Oliver

Building wet planets through high-pressure magma–hydrogen reactions pp. 1069-1074

H. W. Horn, A. Vazan, S. Chariton, V. B. Prakapenka and S.-H. Shim

Continuous operation of a coherent 3,000-qubit system pp. 1075-1080

Neng-Chun Chiu, Elias C. Trapp, Jinen Guo, Mohamed H. Abobeih, Luke M. Stewart, Simon Hollerith, Pavel L. Stroganov, Marcin Kalinowski, Alexandra A. Geim, Simon J. Evered, Sophie H. Li, Xingjian Lyu, Lisa M. Peters, Dolev Bluvstein, Tout T. Wang, Markus Greiner, Vladan Vuletić and Mikhail D. Lukin

A full-featured 2D flash chip enabled by system integration pp. 1081-1088

Chunsen Liu, Yongbo Jiang, Boqian Shen, Shengchao Yuan, Zhenyuan Cao, Zhongyu Bi, Chong Wang, Yutong Xiang, Tanjun Wang, Haoqi Wu, Zizheng Liu, Yang Wang, Shuiyuan Wang and Peng Zhou

Video‐rate tunable colour electronic paper with human resolution pp. 1089-1095

Ade Satria Saloka Santosa, Yu-Wei Chang, Andreas B. Dahlin, Lars Österlund, Giovanni Volpe and Kunli Xiong

Ultrasound-driven programmable artificial muscles pp. 1096-1104

Zhan Shi, Zhiyuan Zhang, Justus Schnermann, Stephan C. F. Neuhauss, Nitesh Nama, Raphael Wittkowski and Daniel Ahmed

Decoding the redox behaviour of copper in Ullmann-type coupling reactions pp. 1105-1113

Yongrui Luo, Yuli Li, Botao Wu, Guangyu Wang, Jian Wu, Sheng-Ye Zhang, K. N. Houk and Qilong Shen

A circular economy approach for the global lithium-ion battery supply chain pp. 1114-1121

Mengyu Zhai, Yufeng Wu, Shaonan Tian, Haoran Yuan, Bin Li, Xubiao Luo, Guohe Huang, Yupeng Fu, Mengye Zhu, Yifan Gu, Wei Huan, Yu Dai, Huaidong Wang, Liming Yang, Xiaofei Yin, Gongqi Liu, Zhi Li, Jing Gu, Yazhuo Wang, Yong Chen and Tieyong Zuo

Magnetotelluric evidence for a melt-rich magmatic reservoir beneath Mayotte pp. 1122-1128

Pierre Wawrzyniak, Fabrice Gaillard, Sophie Hautot, Juan Andujar, Pascal Tarits, Laurent Arbaret, Samuel Guegan, David Sifré, Jean-François D’Eu, Jacques Deparis, Anne Lemoine, Isabelle Thinon, Sheldon Warden and Frédéric Dubois

Age and gender distortion in online media and large language models pp. 1129-1137

Douglas Guilbeault, Solène Delecourt and Bhargav Srinivasa Desikan

A domed pachycephalosaur from the early Cretaceous of Mongolia pp. 1138-1145

Tsogtbaatar Chinzorig, Ryuji Takasaki, Junki Yoshida, Ryan T. Tucker, Batsaikhan Buyantegsh, Buuvei Mainbayar, Khishigjav Tsogtbaatar and Lindsay E. Zanno

Polygenic and developmental profiles of autism differ by age at diagnosis pp. 1146-1155

Xinhe Zhang, Jakob Grove, Yuanjun Gu, Cornelia K. Buus, Lea K. Nielsen, Sharon A. S. Neufeld, Mahmoud Koko, Daniel S. Malawsky, Emma M. Wade, Ellen Verhoef, Anna Gui, Laura Hegemann, Daniel H. Geschwind, Naomi R. Wray, Alexandra Havdahl, Angelica Ronald, Beate Pourcain, Elise B. Robinson, Thomas Bourgeron, Simon Baron-Cohen, Anders D. Børglum, Hilary C. Martin and Varun Warrier

Transitions in dynamical regime and neural mode during perceptual decisions pp. 1156-1166

Thomas Zhihao Luo, Timothy Doyeon Kim, Diksha Gupta, Adrian G. Bondy, Charles D. Kopec, Verity A. Elliott, Brian DePasquale and Carlos D. Brody

A neuronal architecture underlying autonomic dysreflexia pp. 1167-1177

Jan Elaine Soriano, Remi Hudelle, Lois Mahe, Matthieu Gautier, Alan Yue Yang Teo, Michael A. Skinnider, Achilleas Laskaratos, Steven Ceto, Claudia Kathe, Thomas Hutson, Rebecca Charbonneau, Fady Girgis, Steve Casha, Julien Rimok, Marcus Tso, Kelly Larkin-Kaiser, Nicolas Hankov, Aasta Gandhi, Suje Amir, Xiaoyang Kang, Yashwanth Vyza, Eduardo Martin-Moraud, Stephanie Lacour, Robin Demesmaeker, Leonie Asboth, Quentin Barraud, Mark A. Anderson, Jocelyne Bloch, Jordan W. Squair, Aaron A. Phillips and Gregoire Courtine

PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia pp. 1178-1186

Alena Kozlova, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Stanislau Smirnou, Seul Kee Byeon, Christina Thapa, Xiaotong Sun, Kimberley Stephenson, Xiaojie Zhao, Brendan Jamison, Moorthi Ponnusamy, Xin He, Julie A. Schneider, Akhilesh Pandey, David A. Bennett, Zhiping P. Pang, Alan R. Sanders, Hugo J. Bellen, Gopal Thinakaran and Jubao Duan

Energy deficiency selects crowded live epithelial cells for extrusion pp. 1187-1194

Saranne J. Mitchell, Carlos Pardo-Pastor, Anastassia Tchoumakova, Thomas A. Zangle and Jody Rosenblatt

Programmable antisense oligomers for phage functional genomics pp. 1195-1203

Milan Gerovac, Leandro Buhlmann, Yan Zhu, Svetlana Ðurica-Mitić, Valentin Rech, Samuel Carien, Tom Gräfenhan, Linda Popella and Jörg Vogel

Monoclonal antibodies protect against pandrug-resistant Klebsiella pneumoniae pp. 1204-1213

Emanuele Roscioli, Vittoria Zucconi Galli Fonseca, Soraya Soledad Bosch, Ida Paciello, Giuseppe Maccari, Giulia Cardinali, Giampiero Batani, Samuele Stazzoni, Giusy Tiseo, Cesira Giordano, Shen Yuwei, Laura Capoccia, Dario Cardamone, Matteo Ridelfi, Marco Troisi, Noemi Manganaro, Chiara Mugnaini, Concetta De Santi, Annalisa Ciabattini, Linda Cerofolini, Marco Fragai, Danilo Licastro, Kelly Wyres, Laurent Dortet, Simona Barnini, David P. Nicolau, Francesco Menichetti, Marco Falcone, Kamilia Abdelraouf, Claudia Sala, Anna Kabanova and Rino Rappuoli

Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours pp. 1214-1222

Samarth Hegde, Bruno Giotti, Brian Y. Soong, Laszlo Halasz, Jessica Berichel, Maximilian M. Schaefer, Benoit Kloeckner, Raphaël Mattiuz, Matthew D. Park, Assaf Magen, Adam Marks, Meriem Belabed, Pauline Hamon, Theodore Chin, Leanna Troncoso, Juliana J. Lee, Kaili Fan, Dughan Ahimovic, Michael J. Bale, Kai Nie, Grace Chung, Darwin D’souza, Krista Angeliadis, Seunghee Kim-Schulze, Raja M. Flores, Andrew J. Kaufman, Florent Ginhoux, Jason D. Buenrostro, Steven Z. Josefowicz, Alexander M. Tsankov, Thomas U. Marron, Sai Ma, Brian D. Brown and Miriam Merad

Peroxisomal metabolism of branched fatty acids regulates energy homeostasis pp. 1223-1231

Xuejing Liu, Anyuan He, Dongliang Lu, Donghua Hu, Min Tan, Abenezer Abere, Parniyan Goodarzi, Bilal Ahmad, Brian Kleiboeker, Brian N. Finck, Mohamed Zayed, Katsuhiko Funai, Jonathan R. Brestoff, Ali Javaheri, Patricia Weisensee, Bettina Mittendorfer, Fong-Fu Hsu, Paul P. Veldhoven, Babak Razani, Clay F. Semenkovich and Irfan J. Lodhi

Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis pp. 1232-1242

Solomiia Savchuk, Kaylee M. Gentry, Wengang Wang, Elana Carleton, Carlos A. O. Biagi-Junior, Karan Luthria, Belgin Yalçın, Lijun Ni, Hannah C. Farnsworth, Rachel A. Davis, Richard Drexler, Johannes C. Melms, Yin Liu, Lehi Acosta-Alvarez, Griffin G. Hartmann, Elisa C. Pavarino, Jenna LaBelle, Pamelyn J. Woo, Angus M. Toland, Fangfei Qu, Yoon Seok Kim, Mariella G. Filbin, Mark A. Krasnow, Keith L. Ligon, Benjamin Izar, Julien Sage, Bernardo L. Sabatini, Michelle Monje and Humsa S. Venkatesh

Functional synapses between neurons and small cell lung cancer pp. 1243-1253

Vignesh Sakthivelu, Anna Schmitt, Franka Odenthal, Kristiano Ndoci, Marian Touet, Ali H. Shaib, Abdulla Chihab, Gulzar A. Wani, Pascal Nieper, Griffin G. Hartmann, Isabel Pintelon, Ilmars Kisis, Maike Boecker, Naja M. Eckert, Manoela Iannicelli Caiaffa, Olta Ibruli, Julia Weber, Roman Maresch, Christina M. Bebber, Ali Chitsaz, Anna Lütz, Mira Kim Alves Carpinteiro, Kaylee M. Morris, Camilla A. Franchino, Jonas Benz, Laura Pérez-Revuelta, Jorge A. Soriano-Campos, Maxim A. Huetzen, Jonas Goergens, Milica Jevtic, Hannah M. Jahn-Kelleter, Hans Zempel, Aleksandra Placzek, Alexandru A. Hennrich, Karl-Klaus Conzelmann, Hannah L. Tumbrink, Pascal Hunold, Joerg Isensee, Lisa Werr, Felix Gaedke, Astrid Schauss, Marielle Minère, Marie Müller, Henning Fenselau, Yin Liu, Alena Heimsoeth, Gülce S. Gülcüler Balta, Henning Walczak, Christian Frezza, Ron D. Jachimowicz, Julie George, Marcel Schmiel, Johannes Brägelmann, Tim Hucho, Silvia Karstedt, Martin Peifer, Alessandro Annibaldi, Robert Hänsel-Hertsch, Thorsten Persigehl, Holger Grüll, Martin L. Sos, Guido Reifenberger, Matthias Fischer, Dirk Adriaensen, Reinhard Büttner, Julien Sage, Inge Brouns, Roland Rad, Roman K. Thomas, Max Anstötz, Silvio O. Rizzoli, Matteo Bergami, Elisa Motori, Hans Christian Reinhardt and Filippo Beleggia

Engineered prime editors with minimal genomic errors pp. 1254-1260

Vikash P. Chauhan, Phillip A. Sharp and Robert Langer

Spatial joint profiling of DNA methylome and transcriptome in tissues pp. 1261-1271

Chin Nien Lee, Hongxiang Fu, Angelysia Cardilla, Wanding Zhou and Yanxiang Deng

Structure and mechanism of the mitochondrial calcium transporter NCLX pp. 1272-1280

Minrui Fan, Chen-Wei Tsai, Jinru Zhang, Jianxiu Zhang, Aswini R. Krishnan, Tsung-Yun Liu, Yu-Lun Huang, Deniz Aydin, Siyuan Du, Briana L. Sobecks, Madison X. Rodriguez, Andrew H. Reiter, Carolyn R. Bertozzi, Ron O. Dror, Ming-Feng Tsai and Liang Feng

Cake to the rescue: how these PhD students are cooking up a sense of community pp. 1281-1282

Sarah Wells

Preserving Pompeii’s past, one step at a time pp. 1284-1284

Agnese Abrusci

2025, volume 646, articles 8086

Uncertain climate effects of anthropogenic reactive nitrogen pp. E4-E9

Øivind Hodnebrog, Caroline Jouan, Didier A. Hauglustaine, Fabien Paulot, Susanne E. Bauer, Maureen Beaudor, Michael J. Prather, Marit Sandstad, Ragnhild B. Skeie and Gunnar Myhre

Reply to: Uncertain climate effects of anthropogenic reactive nitrogen pp. E10-E12

Cheng Gong, Hanqin Tian, Hong Liao, Naiqing Pan, Shufen Pan, Akihiko Ito, Atul K. Jain, Sian Kou-Giesbrecht, Fortunat Joos, Qing Sun, Hao Shi, Nicolas Vuichard, Qing Zhu, Changhui Peng, Federico Maggi, Fiona H. M. Tang and Sönke Zaehle

Author Correction: Clonal dynamics and somatic evolution of haematopoiesis in mouse pp. E13-E13

Chiraag D. Kapadia, Nicholas Williams, Kevin J. Dawson, Caroline Watson, Matthew J. Yousefzadeh, Duy Le, Kudzai Nyamondo, Sreeya Kodavali, Alex Cagan, Sarah Waldvogel, Xiaoyan Zhang, Josephine Fuente, Daniel Leongamornlert, Emily Mitchell, Marcus A. Florez, Krzysztof Sosnowski, Rogelio Aguilar, Alejandra Martell, Anna Guzman, David Harrison, Laura J. Niedernhofer, Katherine Y. King, Peter J. Campbell, Jamie Blundell, Margaret A. Goodell and Jyoti Nangalia

Author Correction: Mechanism of BRCA1–BARD1 function in DNA end resection and DNA protection pp. E14-E14

Ilaria Ceppi, Maria Rosaria Dello Stritto, Martin Mütze, Stefan Braunshier, Valentina Mengoli, Giordano Reginato, Hồ Mỹ Phúc Võ, Sonia Jimeno, Ananya Acharya, Megha Roy, Aurore Sanchez, Swagata Halder, Sean Michael Howard, Raphaël Guérois, Pablo Huertas, Sylvie M. Noordermeer, Ralf Seidel and Petr Cejka

Author Correction: Selenium-alloyed tellurium oxide for amorphous p-channel transistors pp. E15-E15

Ao Liu, Yong-Sung Kim, Min Gyu Kim, Youjin Reo, Taoyu Zou, Taesu Choi, Sai Bai, Huihui Zhu and Yong-Young Noh

Publisher Correction: Multimodal cell maps as a foundation for structural and functional genomics pp. E16-E16

Leah V. Schaffer, Mengzhou Hu, Gege Qian, Kyung-Mee Moon, Abantika Pal, Neelesh Soni, Andrew P. Latham, Laura Pontano Vaites, Dorothy Tsai, Nicole M. Mattson, Katherine Licon, Robin Bachelder, Anthony Cesnik, Ishan Gaur, Trang Le, William Leineweber, Aji Palar, Ernst Pulido, Yue Qin, Xiaoyu Zhao, Christopher Churas, Joanna Lenkiewicz, Jing Chen, Keiichiro Ono, Dexter Pratt, Peter Zage, Ignacia Echeverria, Andrej Sali, J. Wade Harper, Steven P. Gygi, Leonard J. Foster, Edward L. Huttlin, Emma Lundberg and Trey Ideker

Publisher Correction: Functional synapses between neurons and small cell lung cancer pp. E17-E17

Vignesh Sakthivelu, Anna Schmitt, Franka Odenthal, Kristiano Ndoci, Marian Touet, Ali H. Shaib, Abdulla Chihab, Gulzar A. Wani, Pascal Nieper, Griffin G. Hartmann, Isabel Pintelon, Ilmars Kisis, Maike Boecker, Naja M. Eckert, Manoela Iannicelli Caiaffa, Olta Ibruli, Julia Weber, Roman Maresch, Christina M. Bebber, Ali Chitsaz, Anna Lütz, Mira Kim Alves Carpinteiro, Kaylee M. Morris, Camilla A. Franchino, Jonas Benz, Laura Pérez-Revuelta, Jorge A. Soriano-Campos, Maxim A. Huetzen, Jonas Goergens, Milica Jevtic, Hannah M. Jahn-Kelleter, Hans Zempel, Aleksandra Placzek, Alexandru A. Hennrich, Karl-Klaus Conzelmann, Hannah L. Tumbrink, Pascal Hunold, Joerg Isensee, Lisa Werr, Felix Gaedke, Astrid Schauss, Marielle Minère, Marie Müller, Henning Fenselau, Yin Liu, Alena Heimsoeth, Gülce S. Gülcüler Balta, Henning Walczak, Christian Frezza, Ron D. Jachimowicz, Julie George, Marcel Schmiel, Johannes Brägelmann, Tim Hucho, Silvia Karstedt, Martin Peifer, Alessandro Annibaldi, Robert Hänsel-Hertsch, Thorsten Persigehl, Holger Grüll, Martin L. Sos, Guido Reifenberger, Matthias Fischer, Dirk Adriaensen, Reinhard Büttner, Julien Sage, Inge Brouns, Roland Rad, Roman K. Thomas, Max Anstötz, Silvio O. Rizzoli, Matteo Bergami, Elisa Motori, Hans Christian Reinhardt and Filippo Beleggia

We need more than good science to fight infectious disease pp. S23-S23

Bec Crew

Measles, polio, tuberculosis: what’s causing spikes in infectious diseases? pp. S24-S27

Rachel Nuwer

Four game-changing immunology tools to watch pp. S30-S32

Gemma Conroy

The TrumpRx website won’t slash drug prices — but this will pp. 777-777

Beth Woods

Mysterious cosmic ‘dots’ are baffling astronomers. What are they? pp. 779-780

Jenna Ahart

Global health is in crisis — who will step in to fix it? pp. 780-781

Fred Schwaller

Economics Nobel prize won by researchers who showed how science boosts growth pp. 782-783

Philip Ball

First proposed blood test for chronic fatigue syndrome: what scientists think pp. 783-783

David Adam

More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys pp. 784-785

Jenna Ahart

AI bots wrote and reviewed all papers at this conference pp. 786-786

Elizabeth Gibney

Universities are embracing AI: will students get smarter or stop thinking? pp. 788-791

Helen Pearson

How to spot fake scientists and stop them from publishing papers pp. 792-794

Miryam Naddaf

Why we still don’t understand the Universe — even after a century of dispute pp. 795-796

Helge Kragh

Mark Norell obituary: palaeontologist who showed that dinosaurs still walk among us — as birds pp. 797-797

Michael J. Novacek

Alternatives to animal testing are the future — it’s time that journals, funders and scientists embrace them pp. 799-801

Todd J. Herron, Anke Brüning-Richardson, Julie E. Gough, Aline F. Miller, Geoffrey J. Pilkington, John Greenman, Valerie Speirs and Joseph C. Wu

Why simply ending animal testing isn’t the answer in biomedical research pp. 802-803

K. C. Kent Lloyd

Brazil must beef up its COP30 scheme to preserve tropical forests pp. 804-804

James D. Langston, Daniel S. Mendham, Ali Yansyah Abdurrahim and Jatna Supriatna

The race for deep-sea minerals could cause geopolitical and ecological harm pp. 804-804

Milad Haghani, Abbas Rajabifard, Thomas Wiedmann and David A. Hensher

Take the time to ensure that AI is safe pp. 804-804

Sam Illingworth

Genetics can give evolving societies a leg up pp. 804-804

Andrew J. Doig

Clues to why the weight-loss condition cachexia arises when cancer occurs pp. 805-806

Kerstin Haase and Mariam Jamal-Hanjani

Copper-free chips generate robust ‘combs’ of multicoloured light pp. 806-807

Mher Ghulinyan and Martino Bernard

Boosting immune cells to combat cancer using CRISPR engineering and large-scale in vivo testing pp. 808-809

Michael Hudecek

Is there a ‘smoking gun’ test for quantum gravity? pp. 809-811

Zachary Weller-Davies

How a tick-borne virus enters human cells pp. 811-812

Yaw Shin Ooi

Classical theories of gravity produce entanglement pp. 813-817

Joseph Aziz and Richard Howl

Optimization by decoded quantum interferometry pp. 831-836

Stephen P. Jordan, Noah Shutty, Mary Wootters, Adam Zalcman, Alexander Schmidhuber, Robbie King, Sergei V. Isakov, Tanuj Khattar and Ryan Babbush

A metallic p-wave magnet with commensurate spin helix pp. 837-842

Rinsuke Yamada, Max T. Birch, Priya R. Baral, Shun Okumura, Ryota Nakano, Shang Gao, Motohiko Ezawa, Takuya Nomoto, Jan Masell, Yuki Ishihara, Kamil K. Kolincio, Ilya Belopolski, Hajime Sagayama, Hironori Nakao, Kazuki Ohishi, Takashi Ohhara, Ryoji Kiyanagi, Taro Nakajima, Yoshinori Tokura, Taka-hisa Arima, Yukitoshi Motome, Moritz M. Hirschmann and Max Hirschberger

Deterministic soliton microcombs in Cu-free photonic integrated circuits pp. 843-849

Xinru Ji, Xurong Li, Zheru Qiu, Rui Ning Wang, Marta Divall, Andrey Gelash, Grigory Lihachev and Tobias J. Kippenberg

Cryogenic X-ray photoelectron spectroscopy for battery interfaces pp. 850-855

Sanzeeda Baig Shuchi, Giulio D’Acunto, Philaphon Sayavong, Solomon T. Oyakhire, Kenzie M. Sanroman Gutierrez, Juliet Risner-Jamtgaard, Il Rok Choi, Yi Cui and Stacey F. Bent

Modern sea-level rise breaks 4,000-year stability in southeastern China pp. 856-864

Yucheng Lin, Robert E. Kopp, Haixian Xiong, Fiona D. Hibbert, Zhuo Zheng, Fengling Yu, Praveen Kumar, Sönke Dangendorf, Hailin Yi and Yaze Zhang

In situ light-field imaging of octopus locomotion reveals simplified control pp. 865-871

Kakani Katija, Christine L. Huffard, Paul L. D. Roberts, Joost Daniels, Jon Erickson, Denis Klimov, Henry A. Ruhl and Alana D. Sherman

A compressed hierarchy for visual form processing in the tree shrew pp. 872-882

Frank F. Lanfranchi, Joseph Wekselblatt, Daniel A. Wagenaar and Doris Y. Tsao

Rate and noise in human amygdala drive increased exploration in aversive learning pp. 883-892

Tamar Reitich-Stolero, Kristoffer C. Aberg, Dean Halperin, Carmel Ariel, Genela Morris, Lilach Goldstein, Firas Fahoum, Ido Strauss and Rony Paz

Human gastroids to model regional patterning in early stomach development pp. 893-902

Xia Li, Feng Lin, Qiqi Cui, Shiyu Sun, Shixin Li, Yue Wang, Yiting Wang, Jianbo Bai, Shiyi Liu, Jia Guo, Yizhao Han, Meiru Zhang, Tie Chang, Yifan Zheng, Jianlin Liu, Longqi Liu, Leyun Wang, Jianping Fu, Xin Liu, Bing Bai and Yue Shao

Therapeutic genetic restoration through allogeneic brain microglia replacement pp. 903-912

Marius Marc-Daniel Mader, Alexa Scavetti, Yongjin Yoo, Aaron Tianyue Chai, Takeshi Uenaka and Marius Wernig

Microglia–neuron crosstalk through Hex–GM2–MGL2 maintains brain homeostasis pp. 913-924

Maximilian Frosch, Takashi Shimizu, Emile Wogram, Lukas Amann, Lars Gruber, Ayelén I. Groisman, Maximilian Fliegauf, Marius Schwabenland, Chintan Chhatbar, Sabrina Zechel, Hendrik Rosewich, Jutta Gärtner, Francisco J. Quintana, Joerg M. Buescher, Thomas Blank, Harald Binder, Christine Stadelmann, Johannes J. Letzkus, Carsten Hopf, Takahiro Masuda, Klaus-Peter Knobeloch and Marco Prinz

Microbial iron oxide respiration coupled to sulfide oxidation pp. 925-933

Song-Can Chen, Xiao-Min Li, Nicola Battisti, Guoqing Guan, Maria A. Montoya, Jay Osvatic, Petra Pjevac, Shaul Pollak, Andreas Richter, Arno Schintlmeister, Wolfgang Wanek, Marc Mussmann and Alexander Loy

Dynamic fibroblast–immune interactions shape recovery after brain injury pp. 934-944

Nathan A. Ewing-Crystal, Nicholas M. Mroz, Amara Larpthaveesarp, Carlos O. Lizama, Remy Pennington, Pailin Chiaranunt, Jason I. Dennis, Anthony A. Chang, Eric Dean Merrill, Sofia E. Caryotakis, Nikhita Kirthivasan, Leon Teo, Tatsuya Tsukui, Aditya Katewa, Gabriel L. McKinsey, Sophia C. K. Nelson, Agnieszka Ciesielska, Nicole C. Lummis, Lucija Pintarić, Madelene W. Dahlgren, Amha Atakilit, Helena Paidassi, Saket Jain, Xiaodan Liu, Duan Xu, Manish K. Aghi, James A. Bourne, Jeanne T. Paz, Richard Daneman, Fernando F. Gonzalez, Dean Sheppard, Anna V. Molofsky, Thomas D. Arnold and Ari B. Molofsky

LRP8 is a receptor for tick-borne encephalitis virus pp. 945-952

Eva Mittler, Alexandra L. Tse, Pham-Tue-Hung Tran, Catalina Florez, Javier Janer, Renata Varnaite, Ezgi Kasikci, Vasantha Kumar Mv, Michaela Loomis, Wanda Christ, Erik Cazares, Russell R. Bakken, Caroline K. Martin, Xiankun Zeng, Jo Lynne Raymond, Mansoureh Shahsavani, Sara Khanal, Eric R. Wilkinson, Rischa Maya Oktavia, Megan M. Slough, Denise Haslwanter, Julianna Han, Jacob Berrigan, Ebba Rosendal, Margaret Kielian, Balaji Manicassamy, Anna K. Överby, Anna Falk, Giovanna Barba-Spaeth, Felix A. Rey, Jonas Klingström, Evripidis Gavathiotis, Andrew S. Herbert, Kartik Chandran and Sara Gredmark-Russ

In vivo CRISPR screens identify modifiers of CAR T cell function in myeloma pp. 953-962

Nelson H. Knudsen, Giulia Escobar, Felix Korell, Tamina Kienka, Celeste Nobrega, Seth Anderson, Andrew Y. Cheng, Maria Zschummel, Alexander Armstrong, Amanda Bouffard, Michael C. Kann, Sadie Goncalves, Hans W. Pope, Mitra Pezeshki, Alexander Rojas, Juliette S. M. T. Suermondt, Merle Phillips, Trisha R. Berger, Sangwoo Park, Diego Salas-Benito, Elijah P. Darnell, Filippo Birocchi, Mark B. Leick, Rebecca C. Larson, John G. Doench, Debattama Sen, Kathleen B. Yates, Robert T. Manguso and Marcela V. Maus

Systematic discovery of CRISPR-boosted CAR T cell immunotherapies pp. 963-972

Paul Datlinger, Eugenia V. Pankevich, Cosmas D. Arnold, Nicole Pranckevicius, Jenny Lin, Daria Romanovskaia, Moritz Schaefer, Francesco Piras, Anne-Christine Orts, Amelie Nemc, Paulina N. Biesaga, Michelle Chan, Teresa Neuwirth, Artem V. Artemov, Wentao Li, Sabrina Ladstätter, Thomas Krausgruber and Christoph Bock

Molecular subtypes of human skeletal muscle in cancer cachexia pp. 973-982

Bhumi J. Bhatt, Sunita Ghosh, Vera Mazurak, Aurélien Q. Brun, Oliver Bathe, Vickie E. Baracos and Sambasivarao Damaraju

CRISPR activation for SCN2A-related neurodevelopmental disorders pp. 983-991

Serena Tamura, Andrew D. Nelson, Perry W. E. Spratt, Elizabeth C. Hamada, Xujia Zhou, Henry Kyoung, Zizheng Li, Coline Arnould, Vladyslav Barskyi, Beniamin Krupkin, Kiana Young, Jingjing Zhao, Stephanie S. Holden, Atehsa Sahagun, Caroline M. Keeshen, Congyi Lu, Roy Ben-Shalom, Sunrae E. Taloma, Selin Schamiloglu, Ying C. Li, Lia Min, Paul M. Jenkins, Jen Q. Pan, Jeanne T. Paz, Stephan J. Sanders, Navneet Matharu, Nadav Ahituv and Kevin J. Bender

DNA2 enables growth by restricting recombination-restarted replication pp. 992-1000

Jessica J. R. Hudson, Rowin Appanah, David Jones, Kathryn Davidson, Alice M. Budden, Alina Vaitsiankova, Kok-Lung Chan, Keith W. Caldecott, Antony M. Carr and Ulrich Rass

Multiple overlapping binding sites determine transcription factor occupancy pp. 1001-1011

Shubham Khetan, Brent S. Carroll and Martha L. Bulyk

Are these the happiest PhD students in the world? pp. 1013-1016

Linda Nordling

Cold plunge: how I gained hands-on experience in marine biology pp. 1018-1018

Nikki Forrester

2025, volume 646, articles 8085

How journals can break down barriers for Latin American scientists pp. 517-517

Mariana Viglino

Inside our university’s mission to pivot to research pp. 518-518

Doreen Ramogola-Masire

Medicine Nobel goes to scientists who revealed secrets of immune system ‘regulation’ pp. 521-522

Miryam Naddaf and Elizabeth Gibney

Chemistry Nobel for scientists who developed massively porous ‘super sponge’ materials pp. 522-523

Davide Castelvecchi and Miryam Naddaf

Groundbreaking quantum-tunnelling experiments win physics Nobel pp. 523-524

Elizabeth Gibney and Davide Castelvecchi

Creative hobbies could slow brain ageing at the molecular level pp. 524-525

Gemma Conroy

First human transplant of kidney modified to have ‘universal’ blood type pp. 525-525

Rachel Fieldhouse

The rise of ‘nightmare bacteria’: antimicrobial resistance in five charts pp. 526-527

Katie Kavanagh

‘Google for DNA’ brings order to biology’s big data pp. 528-528

Elie Dolgin

Faulty mitochondria cause deadly diseases: fixing them is about to get a lot easier pp. 530-532

Gemma Conroy

The quest to make babies with lab-grown eggs and sperm pp. 534-536

Heidi Ledford

Alchemy: discredited pseudoscience or chemistry’s worthy ancestor? pp. 537-538

Kit Chapman

The race to uncover snow’s many mysteries before it disappears forever pp. 539-540

Gareth Thompson

Jane Goodall obituary: pioneer primatologist who inspired generations of scientists pp. 541-541

Richard Wrangham

Carbon credits are failing to help with climate change — here’s why pp. 543-546

Andrew Macintosh, Gregory Trencher, Benedict Probst, Shanta Barley, Danny Cullenward, Thales A. P. West, Don Butler and Johan Rockström

Metals are key to the global economy — but three challenges threaten supply chains pp. 547-549

Tarasankar DebRoy, Todd A. Palmer, John W. Elmer and Tuhin Mukherjee

AI’s therapeutic potential goes beyond emotional connection pp. 550-550

Elad Refoua, Eshkol Rafaeli and Dorit Hadar Shoval

Red lines for religious AI pp. 550-550

Max Tretter and Anna Puzio

Longer grant cycles would boost research in Africa pp. 550-550

Fulufhelo Nemavhola

Brazil’s COP30 legacy should be to protect more of its forests pp. 550-550

Paulo Moutinho and André Guimarães

Ion stencils used for synthesis of patchy nanoparticles pp. 551-552

Ilona Kretzschmar and Emanuela Bianchi

Flies evolved a shock-absorber tissue used during embryonic development pp. 552-554

Thibaut Brunet

Birds’ intruder alert hints at how sounds took on new meanings pp. 554-554

Holly Smith

Extreme confinement unleashes water’s hidden electrical capabilities pp. 555-556

Neus Domingo and Albert Verdaguer

Caribbean coral reefs are threatened by rising seas pp. 556-558

Nicola K. Browne

A drug–diet combination could improve childhood cancer treatment pp. 558-559

Frank Speleman and Louis Delhaye

Efficient quantum thermal simulation pp. 561-566

Chi-Fang Chen, Michael Kastoryano, Fernando G. S. L. Brandão and András Gilyén

Integrated lithium niobate photonics for sub-ångström snapshot spectroscopy pp. 567-575

Zhiyang Yao, Shuyang Liu, Yingce Wang, Xiaoyun Yuan and Lu Fang

Proximal cooperative aerial manipulation with vertically stacked drones pp. 576-583

Huazi Cao, Jiahao Shen, Yin Zhang, Zheng Fu, Cunjia Liu, Sihao Sun and Shiyu Zhao

Long-distance remote epitaxy pp. 584-591

Ru Jia, Yan Xin, Mark Potter, Jie Jiang, Zixu Wang, Hanxue Ma, Zhihao Zhang, Zhizhuo Liang, Lifu Zhang, Zonghuan Lu, Ruizhe Yang, Saloni Pendse, Yang Hu, Kai Peng, Yilin Meng, Wei Bao, Jun Liu, Gwo-Ching Wang, Toh-Ming Lu, Yunfeng Shi, Hanwei Gao and Jian Shi

Patchy nanoparticles by atomic stencilling pp. 592-600

Ahyoung Kim, Chansong Kim, Tommy Waltmann, Thi Vo, Eun Mi Kim, Junseok Kim, Yu-Tsun Shao, Aaron Michelson, John R. Crockett, Falon C. Kalutantirige, Eric Yang, Lehan Yao, Chu-Yun Hwang, Yugang Zhang, Yu-Shen Liu, Hyosung An, Zirui Gao, Jiyeon Kim, Sohini Mandal, David A. Muller, Kristen A. Fichthorn, Sharon C. Glotzer and Qian Chen

Marcus kinetics control singlet and triplet oxygen evolving from superoxide pp. 601-605

Soumyadip Mondal, Huyen T. K. Nguyen, Robert Hauschild and Stefan A. Freunberger

In-plane dielectric constant and conductivity of confined water pp. 606-610

R. Wang, M. Souilamas, A. Esfandiar, R. Fabregas, S. Benaglia, H. Nevison-Andrews, Q. Yang, J. Normansell, P. Ares, G. Ferrari, A. Principi, A. K. Geim and L. Fumagalli

Aboveground biomass in Australian tropical forests now a net carbon source pp. 611-618

Hannah Carle, David Bauman, Michael N. Evans, Ingrid Coughlin, Oliver Binks, Andrew Ford, Matthew Bradford, Adrienne Nicotra, Helen Murphy and Patrick Meir

Reduced Atlantic reef growth past 2 °C warming amplifies sea-level impacts pp. 619-626

Chris T. Perry, Didier M. Bakker, Alice E. Webb, Steeve Comeau, Ben P. Harvey, Christopher E. Cornwall, Lorenzo Alvarez-Filip, Esmeralda Pérez-Cervantes, John Morris, Ian C. Enochs, Lauren T. Toth, Aaron O’Dea, Erin M. Dillon, Erik H. Meesters and William F. Precht

Patterned invagination prevents mechanical instability during gastrulation pp. 627-636

Bruno C. Vellutini, Marina B. Cuenca, Abhijeet Krishna, Alicja Szałapak, Carl D. Modes and Pavel Tomancak

Divergent evolutionary strategies pre-empt tissue collision in gastrulation pp. 637-646

Bipasha Dey, Verena Kaul, Girish Kale, Maily Scorcelletti, Michiko Takeda, Yu-Chiun Wang and Steffen Lemke

Parent-of-origin effects on complex traits in up to 236,781 individuals pp. 647-656

Robin J. Hofmeister, Théo Cavinato, Roya Karimi, Adriaan Graaf, Fanny-Dhelia Pajuste, Jaanika Kronberg, Nele Taba, Reedik Mägi, Marc Vaudel, Simone Rubinacci, Stefan Johansson, Lili Milani, Olivier Delaneau and Zoltán Kutalik

Single-cell transcriptomic and genomic changes in the ageing human brain pp. 657-666

Ailsa M. Jeffries, Tianxiong Yu, Jennifer S. Ziegenfuss, Allie K. Tolles, Christina E. Baer, Cesar Bautista Sotelo, Yerin Kim, Zhiping Weng and Michael A. Lodato

Network synchrony creates neural filters promoting quiescence in Drosophila pp. 667-675

Davide Raccuglia, Raquel Suárez-Grimalt, Laura Krumm, Anatoli Ender, Cédric B. Brodersen, Sridhar R. Jagannathan, Martin Freire Krück, Niccolò P. Pampaloni, Carolin Rauch, York Winter, Genevieve Yvon-Durocher, Richard Kempter, Jörg R. P. Geiger and David Owald

Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1 pp. 676-686

Diankun Yu, Samhita Jain, Andi Wangzhou, Beika Zhu, Wenyuan Shao, Elena J. Coley-O’Rourke, Stacy Florencio, JaeYeon Kim, Jennifer Ja-Yoon Choi, Mercedes F. Paredes, Tomasz J. Nowakowski, Eric J. Huang and Xianhua Piao

Haematopoietic stem cell number is not solely defined by niche availability pp. 687-696

Shoichiro Takeishi, Tony Marchand, Wade R. Koba, Daniel K. Borger, Chunliang Xu, Chandan Guha, Aviv Bergman, Paul S. Frenette, Kira Gritsman and Ulrich Steidl

Amygdala–liver signalling orchestrates glycaemic responses to stress pp. 697-706

J. R. E. Carty, K. Devarakonda, R. M. O’Connor, A. Krek, D. Espinoza, M. Jimenez-Gonzalez, A. Alvarsson, R. F. Hampton, R. Li, Y. Qiu, S. Petri, A. Shtekler, A. Rajbhandari, K. Conner, M. Bayne, D. Garibay, J. Martin, V. Lehmann, L. Wang, K. Beaumont, I. Kurland, G. C. Yuan, P. J. Kenny and S. A. Stanley

Reprogramming neuroblastoma by diet-enhanced polyamine depletion pp. 707-715

Sarah Cherkaoui, Christina S. Turn, Yuan Yuan, Wenyun Lu, Lifeng Yang, Matthew J. McBride, Caroline Eigenmann, George E. Allen, Olesya O. Panasenko, Lu Zhang, Annette Vu, Kangning Liu, Yimei Li, Om H. Gandhi, Lea F. Surrey, Sandra D. Kienast, Sebastian A. Leidel, Michael Wierer, Eileen White, Joshua D. Rabinowitz, Michael D. Hogarty and Raphael J. Morscher

The Virtual Lab of AI agents designs new SARS-CoV-2 nanobodies pp. 716-723

Kyle Swanson, Wesley Wu, Nash L. Bulaong, John E. Pak and James Zou

Thymic epithelial cells amplify epigenetic noise to promote immune tolerance pp. 724-733

Noah Gamble, Jason A. Caldwell, Joshua McKeever, Caroline Kaiser, Alexandra Bradu, Peyton J. Dooley, Sandy Klemm, William J. Greenleaf, Narutoshi Hibino, Aaron R. Dinner and Andrew S. Koh

Targeting G1–S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors pp. 734-745

Shilpa Singh, Catherine E. Gleason, Min Fang, Yasmin N. Laimon, Vishal Khivansara, Shanhai Xie, Yavuz T. Durmaz, Aniruddha Sarkar, Kenneth Ngo, Varunika Savla, Yixiang Li, Muhannad Abu-Remaileh, Xinyue Li, Marie-Anais Locquet, Bishma Tuladhar, Ranya Odeh, Frances Hamkins-Indik, Daphne He, Miles W. Membreno, Meisam Nosrati, Nathan N. Gushwa, Siegfried S. F. Leung, Breena Fraga-Walton, Luis Hernandez, Miguel P. Baldomero, Bryan M. Lent, David Spellmeyer, Joshua F. Luna, Dalena Hoang, Yuliana Gritsenko, Manesh Chand, Megan K. DeMart, Sammy Metobo, Chinmay Bhatt, Justin A. Shapiro, Kai Yang, Nathan J. Dupper, Andrew T. Bockus, Jinshu Fang, Ramesh Bambal, Peadar Cremin, John G. Doench, James B. Aggen, Li-Fen Liu, Bernard Levin, Evelyn W. Wang, Iolanda Vendrell, Roman Fischer, Benedikt Kessler, Prafulla C. Gokhale, Sabina Signoretti, Alexander Spektor, Constantine Kreatsoulas, Marie Evangelista, Rajinder Singh, David J. Earp, Deepak Nijhawan, Pablo D. Garcia and Matthew G. Oser

Cocaine chemogenetics blunts drug-seeking by synthetic physiology pp. 746-753

Juan L. Gomez, Christopher J. Magnus, Jordi Bonaventura, Oscar Solis, Fallon P. Curry, Marjorie R. Levinstein, Reece C. Budinich, Meghan L. Carlton, Emilya N. Ventriglia, Sherry Lam, Le Wang, Ingrid Schoenborn, William Dunne, Michael Michaelides and Scott M. Sternson

Crystal structures of agonist-bound human cannabinoid receptor CB1 pp. 754-758

Tian Hua, Kiran Vemuri, Spyros P. Nikas, Yiran Wu, Lu Qu, Mengchen Pu, Anisha Korde, Shan Jiang, Jo-Hao Ho, Gye Won Han, Kang Ding, Xuanxuan Li, Haiguang Liu, Michael A. Hanson, Suwen Zhao, Laura M. Bohn, Alexandros Makriyannis, Raymond C. Stevens and Zhi-Jie Liu

Research assessment: a round-up for early-career researchers pp. 759-762

Holly Else

Digital flocks, predators allow ecologists to simulate real-world animal behaviour pp. 763-765

Heather Richardson

Defending Ohuira Bay, Mexico pp. 768-768

Rachael Pells

2025, volume 646, articles 8084

Prizes must recognize machine contributions to discovery pp. 261-261

Dashun Wang

US serial killer case opens door to using cutting-edge DNA data in courts pp. 263-264

Katherine Bourzac

NIH races to spend its 2025 grant money — but fewer projects win funding pp. 264-266

Max Kozlov

China pledges to cut emissions by 2035: what does that mean for the climate? pp. 266-267

Xiaoying You

Swapping old immune cells in the brain with fresh ones could treat disease pp. 267-268

Heidi Ledford

Will your study change the world? This AI tool predicts the impact of your research pp. 268-269

Brian Owens

Want to do disruptive science? Include more rookie researchers pp. 269-270

Katie Kavanagh

See space fireworks and lightning spaghetti — September’s best science images pp. 270-270

Fred Schwaller and Katie Kavanagh

AI models that lie, cheat and plot murder: how dangerous are LLMs really? pp. 272-275

Matthew Hutson

Will AI ever win its own Nobel? Some predict a prize-worthy science discovery soon pp. 276-278

Jenna Ahart

From fossil fuels to ‘green capitalism’: the dilemmas of a just energy transition pp. 279-280

Sophia Kalantzakos

The cutting-edge medical approaches that could transform ageing pp. 281-283

Coleen T. Murphy

Violin therapy: Books in brief pp. 283-283

Andrew Robinson

Stop treating code like an afterthought: record, share and value it pp. 284-286

Roberto Di Cosmo, Sabrina Granger, Konrad Hinsen, Nicolas Jullien, Daniel Le Berre, Violaine Louvet, Camille Maumet, Clémentine Maurice, Raphaël Monat and Nicolas P. Rougier

Customizable AI systems that anyone can adapt bring big opportunities — and even bigger risks pp. 286-287

Yarin Gal and Stephen Casper

Insect biodiversity monitoring must be expanded pp. 288-288

Kris A. G. Wyckhuys, Yves Basset and Owen T. Lewis

Incentives accelerate progress on open access in Spain pp. 288-288

Wenceslao Arroyo-Machado and Daniel Torres-Salinas

Stop destructive fishing in marine protected areas pp. 288-288

Jenna Sullivan-Stack, Estradivari, Elizabeth P. Pike and Fabrice Stephenson

Microbe discovery holds promise for sustainable biotechnology pp. 288-288

Jie Li, Shuwen Liu, Hao Song and Shiming Ding

Ant queens produce sons of two distinct species pp. 289-290

Jessica Purcell

Protests are infectious: mapping rural unrest in Revolutionary France pp. 290-291

Jack A. Goldstone

Depriving brain tumours of an amino acid could enhance chemotherapy pp. 292-293

Daniel Mobilio and Sheila Singh

Sacrificial metal speeds up synthesis of nano-alloys from multiple elements pp. 293-295

Yunqing Kang and Yusuke Yamauchi

Ancient DNA clarifies the early history of the Slavs pp. 295-296

Steffen Patzold

Southward impact excavated magma ocean at the lunar South Pole–Aitken basin pp. 297-302

Jeffrey C. Andrews-Hanna, William F. Bottke, Adrien Broquet, Alexander J. Evans, Gabriel Gowman, Brandon C. Johnson, James T. Keane, Janette N. Levin, Ananya Mallik, Simone Marchi, Samantha A. Moruzzi, Arkadeep Roy and Shigeru Wakita

Low-overhead transversal fault tolerance for universal quantum computation pp. 303-308

Hengyun Zhou, Chen Zhao, Madelyn Cain, Dolev Bluvstein, Nishad Maskara, Casey Duckering, Hong-Ye Hu, Sheng-Tao Wang, Aleksander Kubica and Mikhail D. Lukin

Quantum-amplified global-phase spectroscopy on an optical clock transition pp. 309-314

Leon Zaporski, Qi Liu, Gustavo Velez, Matthew Radzihovsky, Zeyang Li, Simone Colombo, Edwin Pedrozo-Peñafiel and Vladan Vuletić

Heat-rechargeable computation in DNA logic circuits and neural networks pp. 315-322

Tianqi Song and Lulu Qian

Isothermal solidification for high-entropy alloy synthesis pp. 323-330

Qiubo Zhang, Max C. Gallant, Yi Chen, Zhigang Song, Yang Liu, Qi Zheng, Linfeng Chen, Karen. C. Bustillo, Yu Huang, Kristin A. Persson and Haimei Zheng

A ductile chromium–molybdenum alloy resistant to high-temperature oxidation pp. 331-337

Frauke Hinrichs, Georg Winkens, Lena Katharina Kramer, Gabriely Falcão, Ewa M. Hahn, Daniel Schliephake, Michael Konrad Eusterholz, Sandipan Sen, Mathias Christian Galetz, Haruyuki Inui, Alexander Kauffmann and Martin Heilmaier

A room temperature rechargeable all-solid-state hydride ion battery pp. 338-342

Jirong Cui, Ren Zou, Weijin Zhang, Hong Wen, Jingyao Liu, Shangshang Wang, Shukun Liu, Hetong Chen, Wei Liu, Xiaohua Ju, Weiwei Wang, Tao Gan, Jiong Li, Jianping Guo, Teng He, Hujun Cao and Ping Chen

Tailoring polymer electrolyte solvation for 600 Wh kg−1 lithium batteries pp. 343-350

Xue-Yan Huang, Chen-Zi Zhao, Wei-Jin Kong, Nan Yao, Zong-Yao Shuang, Pan Xu, Shuo Sun, Yang Lu, Wen-Ze Huang, Jin-Liang Li, Liang Shen, Xiang Chen, Jia-Qi Huang, Lynden A. Archer and Qiang Zhang

Scalable total synthesis of saxitoxin and related natural products pp. 351-357

Yinliang Guo, Yiheng Li, Sihan Chen, Yige Wu, Oscar Poll, Zhouyang Ren, Zhonglin Liu, Roman Vlkolinsky, Michal Bajo, Christopher K. Prier, Kai-Jiong Xiao, Benjamin F. Cravatt, Marisa Roberto and Phil S. Baran

Epidemiology models explain rumour spreading during France’s Great Fear of 1789 pp. 358-364

Stefano Zapperi, Constant Varlet-Bertrand, Cécile Bastidon, Caterina A. M. Porta and Antoine Parent

Engineered yeast provides rare but essential pollen sterols for honeybees pp. 365-371

Elynor Moore, Raquel T. Sousa, Stella Felsinger, Jonathan A. Arnesen, Jane D. Dyekjær, Dudley I. Farman, Rui F. S. Gonçalves, Philip C. Stevenson, Irina Borodina and Geraldine A. Wright

One mother for two species via obligate cross-species cloning in ants pp. 372-377

Y. Juvé, C. Lutrat, A. Ha, A. Weyna, E. Lauroua, A. C. Afonso Silva, C. Roux, E. Schifani, C. Galkowski, C. Lebas, R. Allio, I. Stoyanov, N. Galtier, B. C. Schlick-Steiner, F. M. Steiner, D. Baas, B. Kaufmann and J. Romiguier

Hominins on Sulawesi during the Early Pleistocene pp. 378-383

Budianto Hakim, Unggul Prasetyo Wibowo, Gerrit D. Bergh, Dida Yurnaldi, Renaud Joannes-Boyau, Akin Duli, Suryatman, Ratno Sardi, Indah Asikin Nurani, Mika Rizki Puspaningrum, Irfan Mahmud, Afdalah Haris, Khairun Al Anshari, Andi Muhammad Saiful, P. Arman Bungaran, Shinatria Adhityatama, Putra Hudlinas Muhammad, Anwar Akib, Nani Somba, Fakhri, Basran Burhan, Zubair Mas’ud, Mark W. Moore, Yinika L. Perston, Wenjing Yu, Maxime Aubert and Adam Brumm

Ancient DNA connects large-scale migration with the spread of Slavs pp. 384-393

Joscha Gretzinger, Felix Biermann, Hellen Mager, Benedict King, Denisa Zlámalová, Luca Traverso, Guido A. Gnecchi Ruscone, Sanni Peltola, Elina Salmela, Gunnar U. Neumann, Rita Radzeviciute, Pavlína Ingrová, Radosław Liwoch, Iwona Wronka, Radomir Jurić, Anna Hyrchała, Barbara Niezabitowska-Wiśniewska, Bartłomiej Bartecki, Beata Borowska, Tomasz Dzieńkowski, Marcin Wołoszyn, Michał Wojenka, Jarosław Wilczyński, Małgorzata Kot, Eric Müller, Jörg Orschiedt, Gunita Zariņa, Päivi Onkamo, Falko Daim, Arnold Muhl, Ralf Schwarz, Marek Majer, Michael McCormick, Jan Květina, Tivadar Vida, Patrick J. Geary, Jiří Macháček, Mario Šlaus, Harald Meller, Walter Pohl, Zuzana Hofmanová and Johannes Krause

A circuit that integrates drive state and social contact to gate mating pp. 394-403

Lindsey D. Salay, Doris Y. Tsao and David J. Anderson

SLC45A4 is a pain gene encoding a neuronal polyamine transporter pp. 404-412

Steven J. Middleton, Sigurbjörn Markússon, Mikael Åkerlund, Justin C. Deme, Mandy Tseng, Wenqianglong Li, Sana R. Zuberi, Gabriel Kuteyi, Peter Sarkies, Georgios Baskozos, Jimena Perez-Sanchez, Adham Farah, Harry L. Hébert, Sylvanus Toikumo, Zhanru Yu, Susan Maxwell, Yin Y. Dong, Benedikt M. Kessler, Henry R. Kranzler, John E. Linley, Blair H. Smith, Susan M. Lea, Joanne L. Parker, Valeriya Lyssenko, Simon Newstead and David L. Bennett

Rewiring of cortical glucose metabolism fuels human brain cancer growth pp. 413-422

Andrew J. Scott, Anjali Mittal, Baharan Meghdadi, Alexandra O’Brien, Justine Bailleul, Palavalasa Sravya, Abhinav Achreja, Weihua Zhou, Jie Xu, Angelica Lin, Kari Wilder-Romans, Ningning Liang, Ayesha U. Kothari, Navyateja Korimerla, Donna M. Edwards, Zhe Wu, Jiane Feng, Sophia Su, Li Zhang, Peter Sajjakulnukit, Anthony C. Andren, Junyoung O. Park, Johanna Hoeve, Vijay Tarnal, Kimberly A. Redic, Nathan R. Qi, Joshua L. Fischer, Ethan Yang, Michael S. Regan, Sylwia A. Stopka, Gerard Baquer, Krithika Suresh, Jann N. Sarkaria, Theodore S. Lawrence, Sriram Venneti, Nathalie Y. R. Agar, Erina Vlashi, Costas A. Lyssiotis, Wajd N. Al-Holou, Deepak Nagrath and Daniel R. Wahl

Discovery of a widespread chemical signalling pathway in the Bacteroidota pp. 423-432

Luis Linares-Otoya, Jaden D. Shirkey, Bhuwan Khatri Chhetri, Amira Mira, Abhishek Biswas, Samuel L. Neff, Maria V. Linares-Otoya, Ye Chen, Julio V. Campos-Florian, Mayar L. Ganoza-Yupanqui, Philip D. Jeffrey, Frederick M. Hughson and Mohamed S. Donia

A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2 pp. 433-441

Benjamin Vollmer, Henriette Ebel, Renate Rees, Julia Nentwig, Thomas Mulvaney, Jürgen Schünemann, Jens Krull, Maya Topf, Dirk Görlich and Kay Grünewald

TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function pp. 442-451

Qian Shen, Hao Wang, Jonathan A. Roco, Xiangpeng Meng, Marita Bosticardo, Marie Hodges, Michael Battaglia, Zhi-Ping Feng, Benjamin James Talks, Jason Powell, Vijaya Baskar Mahalingam Shanmugiah, Julia Chu, Najib M. Rahman, Alguili Elsheikh, Probir Chakravarty, Amalie Grenov, Max Emmerich, Ottavia M. Delmonte, Alexandra F. Freeman, Michael D. Keller, Brahim Belaid, Ilenia Papa, James C. Lee, Pablo F. Cañete, Paula Gonzalez-Figueroa, Yaoyuan Zhang, Hai-Hui Xue, Samra Turajlic, Luigi D. Notarangelo, Muzlifah Haniffa, Lee Ann Garrett-Sinha, Helen M. Parry, Nikolaos I. Kanellakis and Carola G. Vinuesa

Axonal injury is a targetable driver of glioblastoma progression pp. 452-461

Melanie Clements, Wenhao Tang, Zan Florjanic Baronik, Holly Simpson Ragdale, Roger Oria, Dimitrios Volteras, Ian J. White, Gordon Beattie, Imran Uddin, Tchern Lenn, Rachel Lindsay, Sara Castro Devesa, Saketh R. Karamched, Mark F. Lythgoe, Vahid Shahrezaei, Valerie M. Weaver, Ryoichi Sugisawa, Federico Roncaroli, Samuel Marguerat, Ciaran S. Hill and Simona Parrinello

Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy pp. 462-473

Erez N. Baruch, Frederico O. Gleber-Netto, Priyadharsini Nagarajan, Xiayu Rao, Shamima Akhter, Tuany Eichwald, Tongxin Xie, Mohammad Balood, Adebayo Adewale, Shorook Naara, Hinduja N. Sathishkumar, Shajedul Islam, William McCarthy, Brandi J. Mattson, Renata Ferrarotto, Michael K. Wong, Michael A. Davies, Sonali Jindal, Sreyashi Basu, Karine Roversi, Amin Reza Nikpoor, Maryam Ahmadi, Ali Ahmadi, Catherine Harwood, Irene Leigh, Dennis Gong, Paulino Tallón de Lara, Derrick L. Tao, Tara M. Davidson, Nadim J. Ajami, Andrew Futreal, Kunal Rai, Veena Kochat, Micah Castillo, Preethi Gunaratne, Ryan P. Goepfert, Sharia D. Hernandez, Nikhil I. Khushalani, Jing Wang, Stephanie S. Watowich, George A. Calin, Michael R. Migden, Mona Yuan, Naijiang Liu, Yi Ye, William L. Hwang, Paola D. Vermeer, Nisha J. D’Silva, Yuri L. Bunimovich, Dan Yaniv, Jared K. Burks, Javier Gomez, Patrick M. Dougherty, Kenneth Y. Tsai, James P. Allison, Padmanee Sharma, Jennifer A. Wargo, Jeffrey N. Myers, Sebastien Talbot, Neil D. Gross and Moran Amit

Quantitative imaging of lipid transport in mammalian cells pp. 474-482

Juan M. Iglesias-Artola, Kristin Böhlig, Kai Schuhmann, Katelyn C. Cook, H. Mathilda Lennartz, Milena Schuhmacher, Pavel Barahtjan, Cristina Jiménez López, Radek Šachl, Vannuruswamy Garikapati, Karina Pombo-Garcia, Annett Lohmann, Petra Riegerová, Martin Hof, Björn Drobot, Andrej Shevchenko, Alf Honigmann and André Nadler

One-shot design of functional protein binders with BindCraft pp. 483-492

Martin Pacesa, Lennart Nickel, Christian Schellhaas, Joseph Schmidt, Ekaterina Pyatova, Lucas Kissling, Patrick Barendse, Jagrity Choudhury, Srajan Kapoor, Ana Alcaraz-Serna, Yehlin Cho, Kourosh H. Ghamary, Laura Vinué, Brahm J. Yachnin, Andrew M. Wollacott, Stephen Buckley, Adrie H. Westphal, Simon Lindhoud, Sandrine Georgeon, Casper A. Goverde, Georgios N. Hatzopoulos, Pierre Gönczy, Yannick D. Muller, Gerald Schwank, Daan C. Swarts, Alex J. Vecchio, Bernard L. Schneider, Sergey Ovchinnikov and Bruno E. Correia

Structural basis for the dynamic regulation of mTORC1 by amino acids pp. 493-500

Max L. Valenstein, Maximilian Wranik, Pranav V. Lalgudi, Karen Y. Linde-Garelli, Yuri Choi, Raghu R. Chivukula, David M. Sabatini and Kacper B. Rogala

27 things we wish we’d known when we started our PhDs pp. 501-502

Linda Nordling

Biothreat hunters catch dangerous DNA before it gets made pp. 503-505

Matthew Hutson

Connecting the dots: I trace the history of the East Kolkata Wetlands pp. 508-508

Nikki Forrester

2025, volume 646, articles 8083

Hospitals have long been key for research, now their influence is broadening pp. S1-S1

Jack Leeming

Author Correction: A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome pp. E1-E1

Aline C. Simon, Jin C. Zhou, Rajika L. Perera, Frederick Deursen, Cecile Evrin, Marina E. Ivanova, Mairi L. Kilkenny, Ludovic Renault, Svend Kjaer, Dijana Matak-Vinković, Karim Labib, Alessandro Costa and Luca Pellegrini

China’s research hospitals push for prominence pp. S2-S5

Brian Owens

Publisher Correction: Experimental determination of partial charges with electron diffraction pp. E2-E2

Soheil Mahmoudi, Tim Gruene, Christian Schröder, Khalil D. Ferjaoui, Erik Fröjdh, Aldo Mozzanica, Kiyofumi Takaba, Anatoliy Volkov, Julian Maisriml, Vladimir Paunović, Jeroen A. van Bokhoven and Bernhard K. Keppler

Publisher Correction: TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function pp. E3-E3

Qian Shen, Hao Wang, Jonathan A. Roco, Xiangpeng Meng, Marita Bosticardo, Marie Hodges, Michael Battaglia, Zhi-Ping Feng, Benjamin James Talks, Jason Powell, Vijaya Baskar Mahalingam Shanmugiah, Julia Chu, Najib M. Rahman, Alguili Elsheikh, Probir Chakravarty, Amalie Grenov, Max Emmerich, Ottavia M. Delmonte, Alexandra F. Freeman, Michael D. Keller, Brahim Belaid, Ilenia Papa, James C. Lee, Pablo F. Cañete, Paula Gonzalez-Figueroa, Yaoyuan Zhang, Hai-Hui Xue, Samra Turajlic, Luigi D. Notarangelo, Muzlifah Haniffa, Lee Ann Garrett-Sinha, Helen M. Parry, Nikolaos I. Kanellakis and Carola G. Vinuesa

Uniting Africa’s longitudinal cohorts pp. S8-S10

Anna McKie

Trust in the sea-bed mining authority is fragile — here’s how to change that pp. 9-9

Carlos Garcia-Soto

Fixing the imbalance in cancer rates between Black and white women pp. S10-S12

Anna McKie

Six journal rejections and a major rethink: why I’m happy to admit to my research failures, and you should too pp. 10-10

Séverine Toussaert

HELIOS: a microcosm of Asian health with global reach pp. S12-S14

Anna McKie

Trump links autism and Tylenol: is there any truth to it? pp. 13-14

Helen Pearson and Heidi Ledford

Huntington’s disease treated for first time using gene therapy pp. 15-15

Elie Dolgin

World’s first AI-designed viruses a step towards AI-generated life pp. 16-16

Katie Kavanagh

Tipsy bats and perfect pasta: Ig Nobels celebrate ‘improbable’ research pp. 17-18

Chris Simms

Can AI chatbots trigger psychosis? What the science says pp. 18-19

Rachel Fieldhouse

The Moon is rusting — thanks to ‘wind’ blown all the way from Earth pp. 19-20

Alexandra Witze

She lived to 117: what her genes and lifestyle tell us about longevity pp. 20-20

Mariana Lenharo

AI is dreaming up millions of new materials. Are they any good? pp. 22-25

Mark Peplow

How to get the best night’s sleep: what the science says pp. 26-28

Lynne Peeples

Power and profit drive what we eat: here’s why the food system needs a revolution pp. 29-30

Laura Kelly

Public trust in science has declined since COVID — virologists need to unite around safety standards pp. 31-34

Melanie Ott, Olivier Schwartz and Alex Sigal

Technology leaders should ‘pay back’ society to support the common good pp. 34-37

Abilio Almeida

AI tools could reduce the appeal of predatory journals pp. 38-38

Alessandro Maria Selvitella and Kathleen Lois Foster

Add a ‘speculation box’ to research papers pp. 38-38

Milad Malekzadeh

India and Pakistan share flood risks and must combine solutions pp. 38-38

Saheeb Ahmed Kayani

Make cities more walkable, in the real world and in virtual reality pp. 38-38

Mohammad Javad Koohsari and Andrew T. Kaczynski

Childhood eczema linked to mother’s stress during pregnancy pp. 39-40

Abhay P. S. Rathore and Soman N. Abraham

Quantum correlations enhance the sensitivity of room-temperature sensors pp. 40-42

Maja S. Scharnagl and Klemens Hammerer

People are more likely to cheat when they delegate tasks to AI pp. 42-43

Shoko Suzuki

Parachutes inspired by the Japanese art of kirigami pp. 43-45

Pierre-Thomas Brun

Rare skeletal condition caused by enzyme’s failure to rescue a catalytic cycle pp. 45-46

Karen N. Allen

Doughnut of social and planetary boundaries monitors a world out of balance pp. 47-56

Andrew L. Fanning and Kate Raworth

Late fluid flow in a primitive asteroid revealed by Lu–Hf isotopes in Ryugu pp. 62-67

Tsuyoshi Iizuka, Takazo Shibuya, Takehito Hayakawa, Tetsuya Yokoyama, Ikshu Gautam, Makiko K. Haba, Kengo T. M. Ito, Yuki Hibiya, Akira Yamaguchi, Yoshinari Abe, Jérôme Aléon, Conel M. O’D. Alexander, Sachiko Amari, Yuri Amelin, Ken-ichi Bajo, Martin Bizzarro, Audrey Bouvier, Richard W. Carlson, Marc Chaussidon, Byeon-Gak Choi, Nicolas Dauphas, Andrew M. Davis, Tommaso Rocco, Wataru Fujiya, Ryota Fukai, Hiroshi Hidaka, Hisashi Homma, Gary R. Huss, Trevor R. Ireland, Akira Ishikawa, Shoichi Itoh, Noriyuki Kawasaki, Noriko T. Kita, Koki Kitajima, Thorsten Kleine, Shintaro Komatani, Alexander N. Krot, Ming-Chang Liu, Yuki Masuda, Kazuko Motomura, Frédéric Moynier, Kazuhide Nagashima, Izumi Nakai, Ann Nguyen, Larry Nittler, Andreas Pack, Changkun Park, Laurette Piani, Liping Qin, Sara Russell, Naoya Sakamoto, Maria Schönbächler, Lauren Tafla, Haolan Tang, Kentaro Terada, Yasuko Terada, Tomohiro Usui, Sohei Wada, Meenakshi Wadhwa, Richard J. Walker, Katsuyuki Yamashita, Qing-Zhu Yin, Shigekazu Yoneda, Hiroharu Yui, Ai-Cheng Zhang, Tomoki Nakamura, Hiroshi Naraoka, Takaaki Noguchi, Ryuji Okazaki, Kanako Sakamoto, Hikaru Yabuta, Masanao Abe, Akiko Miyazaki, Aiko Nakato, Masahiro Nishimura, Tatsuaki Okada, Toru Yada, Kasumi Yogata, Satoru Nakazawa, Takanao Saiki, Satoshi Tanaka, Fuyuto Terui, Yuichi Tsuda, Sei-ichiro Watanabe, Makoto Yoshikawa, Shogo Tachibana and Hisayoshi Yurimoto

Signal amplification in a solid-state sensor through asymmetric many-body echo pp. 68-73

Haoyang Gao, Leigh S. Martin, Lillian B. Hughes, Nathaniel T. Leitao, Piotr Put, Hengyun Zhou, Nazli U. Koyluoglu, Simon A. Meynell, Ania C. Bleszynski Jayich, Hongkun Park and Mikhail D. Lukin

Spin squeezing in an ensemble of nitrogen–vacancy centres in diamond pp. 74-80

Weijie Wu, Emily J. Davis, Lillian B. Hughes, Bingtian Ye, Zilin Wang, Dominik Kufel, Tasuku Ono, Simon A. Meynell, Maxwell Block, Che Liu, Haopu Yang, Ania C. Bleszynski Jayich and Norman Y. Yao

Industry-compatible silicon spin-qubit unit cells exceeding 99% fidelity pp. 81-87

Paul Steinacker, Nard Dumoulin Stuyck, Wee Han Lim, Tuomo Tanttu, MengKe Feng, Santiago Serrano, Andreas Nickl, Marco Candido, Jesus D. Cifuentes, Ensar Vahapoglu, Samuel K. Bartee, Fay E. Hudson, Kok Wai Chan, Stefan Kubicek, Julien Jussot, Yann Canvel, Sofie Beyne, Yosuke Shimura, Roger Loo, Clement Godfrin, Bart Raes, Sylvain Baudot, Danny Wan, Arne Laucht, Chih Hwan Yang, Andre Saraiva, Christopher C. Escott, Kristiaan Greve and Andrew S. Dzurak

Kirigami-inspired parachutes with programmable reconfiguration pp. 88-94

Danick Lamoureux, Jérémi Fillion, Sophie Ramananarivo, Frédérick P. Gosselin and David Melancon

Toughened self-assembled monolayers for durable perovskite solar cells pp. 95-101

Wenlin Jiang, Geping Qu, Xiaofeng Huang, Xia Chen, Linyuan Chi, Tonghui Wang, Chun-To Wong, Francis R. Lin, Chunlei Yang, Qing Jiang, Shengfan Wu, Jie Zhang and Alex K.-Y. Jen

Probing the heterogeneous nature of LiF in solid–electrolyte interphases pp. 102-107

Xiangsi Liu, Shuyang Li, Chen Yuan, Bizhu Zheng, Gangya Cheng, Yufan Chen, Xingyu Lu, Danyu Gu, Baijiang Lv, Hao Li, Zihan Yan, Hui Qian, Yizhou Zhu, Dalin Sun, Yun Song and Yuxuan Xiang

Connecting chemical and protein sequence space to predict biocatalytic reactions pp. 108-116

Alexandra E. Paton, Daniil A. Boiko, Jonathan C. Perkins, Nicholas I. Cemalovic, Thiago Reschützegger, Gabe Gomes and Alison R. H. Narayan

Precisely defining disease variant effects in CRISPR-edited single cells pp. 117-125

Yuriy Baglaenko, Zepeng Mu, Michelle Curtis, Hafsa M. Mire, Vidyashree Jayanthi, Majd Al Suqri, Cassidy Liu, Ryan Agnew, Aparna Nathan, Annelise Yoo Mah-Som, David R. Liu, Gregory A. Newby and Soumya Raychaudhuri

Delegation to artificial intelligence can increase dishonest behaviour pp. 126-134

Nils Köbis, Zoe Rahwan, Raluca Rilla, Bramantyo Ibrahim Supriyatno, Clara Bersch, Tamer Ajaj, Jean-François Bonnefon and Iyad Rahwan

Eye structure shapes neuron function in Drosophila motion vision pp. 135-142

Arthur Zhao, Eyal Gruntman, Aljoscha Nern, Nirmala Iyer, Edward M. Rogers, Sanna Koskela, Igor Siwanowicz, Marisa Dreher, Miriam A. Flynn, Connor Laughland, Henrique Ludwig, Alexander Thomson, Cullen Moran, Bruck Gezahegn, Davi D. Bock and Michael B. Reiser

Remodelling of corticostriatal axonal boutons during motor learning pp. 143-151

Mengjun Sheng, Di Lu, Richard H. Roth, Fuu-Jiun Hwang, Kaiwen Sheng and Jun B. Ding

A novel bacterial protein family that catalyses nitrous oxide reduction pp. 152-160

Guang He, Weijiao Wang, Gao Chen, Yongchao Xie, Jerry M. Parks, Megan E. Davin, Robert L. Hettich, Konstantinos T. Konstantinidis and Frank E. Löffler

Maternal stress triggers early-life eczema through fetal mast cell programming pp. 161-170

Nadine Serhan, Nasser S. Abdullah, Nadine Gheziel, Alexia Loste, Rüçhan Ekren, Elodie Labit, Anne-Alicia Gonzalez, Giulia Oliva, Pauline Tarot, Camille Petitfils, Gaëlle Payros, Paolo D’Avino, Allison Voisin, Holly Freya Grace Tinsley, Rebecca Gentek, Carole Brosseau, Marie Bodinier, Laurent Reber, Pierre Val, Cezmi A. Akdis, Yasutaka Mitamura, Anand Kumar Andiappan, Jerry Kok Yen Chan, Florent Ginhoux, Amaury François, Nicolas Cénac, Lilian Basso and Nicolas Gaudenzio

EBV induces CNS homing of B cells attracting inflammatory T cells pp. 171-179

Fabienne Läderach, Ioannis Piteros, Éanna Fennell, Elena Bremer, Mette Last, Sandra Schmid, Lisa Rieble, Caroline Campbell, Isis Ludwig-Portugall, Lea Bornemann, Alexander Gruhl, Klaus Eulitz, Paul Gueguen, Juliane Mietz, Anne Müller, Gaetana Pezzino, Jürgen Schmitz, Guido Ferlazzo, Josef Mautner and Christian Münz

mAChR4 suppresses liver disease via GAP-induced antimicrobial immunity pp. 180-189

Cristina Llorente, Fernanda Raya Tonetti, Ryan Bruellman, Rocío Brea, Nuria Pell, Phillipp Hartmann, Luca Maccioni, Hui Han, Noemí Cabré, Junlai Liu, Alvaro Eguileor, Marcos F. Fondevila, Abraham S. Meijnikman, Cynthia L. Hsu, Ameera Alghafri, Rongrong Zhou, Bei Gao, Yi Duan, Peng Zhang, Mark A. Febbraio, Koji Taniguchi, Rodney D. Newberry, Derrick E. Fouts, David A. Brenner, Peter Stärkel, Michael Karin and Bernd Schnabl

Clone copy number diversity is linked to survival in lung cancer pp. 190-197

Piotr Pawlik, Kristiana Grigoriadis, Abigail Bunkum, Helena Coggan, Alexander M. Frankell, Carlos Martinez-Ruiz, Takahiro Karasaki, Ariana Huebner, Andrew Rowan, Jasmin Fisher, Allan Hackshaw, Charles Swanton, Simone Zaccaria and Nicholas McGranahan

Transient APC/C inactivation by mTOR boosts glycolysis during cell cycle entry pp. 198-207

Debasish Paul, Derek L. Bolhuis, Hualong Yan, Sudipto Das, Xia Xu, Christina C. Abbate, Lisa M. M. Jenkins, Michael J. Emanuele, Thorkell Andresson, Jing Huang, John G. Albeck, Nicholas G. Brown and Steven D. Cappell

Establishment of chromatin architecture interplays with embryo hypertranscription pp. 208-217

Guang Yu, Kai Xu, Weikun Xia, Ke Zhang, Qianhua Xu, Lijia Li, Zili Lin, Ling Liu, Bofeng Liu, Zhenhai Du, Xia Chen, Qiang Fan, Fangnong Lai, Wenying Wang, Lijuan Wang, Feng Kong, Chao Wang, Haiqiang Dai, Huili Wang and Wei Xie

A missing enzyme-rescue metabolite as cause of a rare skeletal dysplasia pp. 218-226

Jean Jacobs, Hristiana Lyubenova, Sven Potelle, Johannes Kopp, Isabelle Gerin, Wing Lee Chan, Miguel Rodriguez de los Santos, Wiebke Hülsemann, Martin A. Mensah, Valérie Cormier-Daire, Marieke Joosten, Hennie T. Bruggenwirth, Kyra E. Stuurman, Valancy Miranda, Philippe M. Campeau, Lars Wittler, Julie Graff, Stefan Mundlos, Daniel M. Ibrahim, Emile Van Schaftingen, Björn Fischer-Zirnsak, Uwe Kornak, Nadja Ehmke and Guido T. Bommer

Pre-rRNA spatial distribution and functional organization of the nucleolus pp. 227-235

Yu-Hang Pan, Lin Shan, Yu-Yao Zhang, Zheng-Hu Yang, Yuan Zhang, Shi-Meng Cao, Xiao-Qi Liu, Jun Zhang, Li Yang and Ling-Ling Chen

Molecular mechanism of ultrafast transport by plasma membrane Ca2+-ATPases pp. 236-245

Deivanayagabarathy Vinayagam, Oleg Sitsel, Uwe Schulte, Cristina E. Constantin, Wout Oosterheert, Daniel Prumbaum, Gerd Zolles, Bernd Fakler and Stefan Raunser

How money, politics and technology are redefining the PhD experience in 2025 pp. 247-250

Linda Nordling

Little urchins, mischievous molluscs: my life as a sea champion pp. 252-252

Jack Leeming