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2024, volume 633, articles 8031

Publisher Correction: Single-crystalline metal-oxide dielectrics for top-gate 2D transistors pp. E5-E5

Daobing Zeng, Ziyang Zhang, Zhongying Xue, Miao Zhang, Paul K. Chu, Yongfeng Mei, Ziao Tian and Zengfeng Di

Publisher Correction: Krause corpuscles are genital vibrotactile sensors for sexual behaviours pp. E6-E6

Lijun Qi, Michael Iskols, Rachel S. Greenberg, Jia Yin Xiao, Annie Handler, Stephen D. Liberles and David D. Ginty

Publisher Correction: Precision spectroscopy on 9Be overcomes limitations from nuclear structure pp. E7-E7

Stefan Dickopf, Bastian Sikora, Annabelle Kaiser, Marius Müller, Stefan Ulmer, Vladimir A. Yerokhin, Zoltán Harman, Christoph H. Keitel, Andreas Mooser and Klaus Blaum

Pain: recognizing the power of non-pharmaceutical interventions pp. S25-S25

Herb Brody

How a ‘pain-o-meter’ could improve treatments pp. S26-S27

Elie Dolgin

Could biomarkers mean better pain treatment? pp. S28-S30

James Mitchell Crow

How pain is misunderstood and ignored in women pp. S31-S33

Bianca Nogrady

The gut microbiome and chronic pain pp. S34-S36

Clare Watson

A drug-free prescription for pain pp. S37-S39

Carolyn Brown

Pain researchers must learn from the opioid crisis pp. S40-S40

Clifford Woolf

The trials and triumphs of sustainable science pp. S69-S71

Chris Woolston

We must train specialists in botany and zoology — or risk more devastating extinctions pp. 741-741

Dasheng Liu

‘The standard model is not dead’: ultra-precise particle measurement thrills physicists pp. 745-746

Elizabeth Gibney

Quantum feat: physicists observe entangled quarks for first time pp. 746-747

Dan Garisto

40 million deaths by 2050: toll of drug-resistant infections to rise by 70% pp. 747-748

Miryam Naddaf

Where did viruses come from? AlphaFold and other AIs are finding answers pp. 748-748

Ewen Callaway

Mosquito-borne diseases are surging in Europe — how worried are scientists? pp. 749-749

Miryam Naddaf

Should young kids take the new anti-obesity drugs? What the research says pp. 750-751

Julian Nowogrodzki

Why do we crumble under pressure? Science has the answer pp. 751-752

Jude Coleman

Brain goop that traps hunger neurons drives obesity pp. 752-752

Max Kozlov

What is a cell type, really? The quest to categorize life’s myriad forms pp. 754-756

Amber Dance

Why do obesity drugs seem to treat so many other ailments? pp. 758-760

Mariana Lenharo

Can AI feel distress? Inside a new framework to assess sentience pp. 761-762

Jonathan Kimmelman

Einstein in Oxford: the untold story of an unlikely friendship pp. 763-765

Andrew Robinson

In Asia, alternative proteins are the new clean energy pp. 767-769

Ryan Huling, Doris Lee, Wasamon Nutakul and Samuel Goh

Floating homes need social and political acceptance in the Western world pp. 770-770

Stefan Huebner

More measures needed to ease funding competition in China pp. 770-770

Wangqiang Sun

Gender inequity persists among journal chief editors pp. 770-770

M. Hossein Nowroozzadeh and Somaye Tafraghe

We can’t recreate ancient wilderness environments — but that’s not the point pp. 770-770

Justin Vaughn

Obesity is driven by a build-up of molecular mesh around hunger neurons pp. 771-772

Alexander Dityatev

Small molecules help misplaced proteins hitchhike around cells pp. 773-774

Robert Yvon and Christina M. Woo

Gut microbes fend off harmful bacteria by depriving them of nutrients pp. 774-775

Eric G. Pamer

Oldest and coldest: JWST claims a first for exoplanet imaging pp. 776-777

Isabel Rebollido Vázquez

Lipid recycling by macrophage cells drives the growth of brain cancer pp. 777-778

Lisa Sevenich

On human-in-the-loop optimization of human–robot interaction pp. 779-788

Patrick Slade, Christopher Atkeson, J. Maxwell Donelan, Han Houdijk, Kimberly A. Ingraham, Myunghee Kim, Kyoungchul Kong, Katherine L. Poggensee, Robert Riener, Martin Steinert, Juanjuan Zhang and Steven H. Collins

A temperate super-Jupiter imaged with JWST in the mid-infrared pp. 789-792

E. C. Matthews, A. L. Carter, P. Pathak, C. V. Morley, M. W. Phillips, S. Krishanth P. M., F. Feng, M. J. Bonse, L. A. Boogaard, J. A. Burt, I. J. M. Crossfield, E. S. Douglas, Th. Henning, J. Hom, C.-L. Ko, M. Kasper, A.-M. Lagrange, D. Petit dit de la Roche and F. Philipot

Cooling positronium to ultralow velocities with a chirped laser pulse train pp. 793-797

K. Shu, Y. Tajima, R. Uozumi, N. Miyamoto, S. Shiraishi, T. Kobayashi, A. Ishida, K. Yamada, R. W. Gladen, T. Namba, S. Asai, K. Wada, I. Mochizuki, T. Hyodo, K. Ito, K. Michishio, B. E. O’Rourke, N. Oshima and K. Yoshioka

Ultrahigh electromechanical response from competing ferroic orders pp. 798-803

Baichen Lin, Khuong Phuong Ong, Tiannan Yang, Qibin Zeng, Hui Kim Hui, Zhen Ye, Celine Sim, Zhihao Yen, Ping Yang, Yanxin Dou, Xiaolong Li, Xingyu Gao, Chee Kiang Ivan Tan, Zhi Shiuh Lim, Shengwei Zeng, Tiancheng Luo, Jinlong Xu, Xin Tong, Patrick Wen Feng Li, Minqin Ren, Kaiyang Zeng, Chengliang Sun, Seeram Ramakrishna, Mark B. H. Breese, Chris Boothroyd, Chengkuo Lee, David J. Singh, Yeng Ming Lam and Huajun Liu

Axon-like active signal transmission pp. 804-810

Timothy D. Brown, Alan Zhang, Frederick U. Nitta, Elliot D. Grant, Jenny L. Chong, Jacklyn Zhu, Sritharini Radhakrishnan, Mahnaz Islam, Elliot J. Fuller, A. Alec Talin, Patrick J. Shamberger, Eric Pop, R. Stanley Williams and Suhas Kumar

Micronuclear battery based on a coalescent energy transducer pp. 811-815

Kai Li, Congchong Yan, Junren Wang, Kun Zhu, Junjun Guo, Yugang Zhang, Guozheng Shi, Yuchen Yin, Liwei Cheng, Liang Sun, Yumin Wang, Hailong Zhang, Ying Sun, Jianyu Yuan, Wanli Ma, Guoxun Ji, Zhifang Chai, Yaxing Wang, Xiaoping Ouyang and Shuao Wang

One step from oxides to sustainable bulk alloys pp. 816-822

Shaolou Wei, Yan Ma and Dierk Raabe

Microbial iron limitation in the ocean’s twilight zone pp. 823-827

Jingxuan Li, Lydia Babcock-Adams, Rene M. Boiteau, Matthew R. McIlvin, Lauren E. Manck, Matthias Sieber, Nathan T. Lanning, Randelle M. Bundy, Xiaopeng Bian, Iulia-Mădălina Ștreangă, Benjamin N. Granzow, Matthew J. Church, Jessica N. Fitzsimmons, Seth G. John, Tim M. Conway and Daniel J. Repeta

Forest fire size amplifies postfire land surface warming pp. 828-834

Jie Zhao, Chao Yue, Jiaming Wang, Stijn Hantson, Xianli Wang, Binbin He, Guangyao Li, Liang Wang, Hongfei Zhao and Sebastiaan Luyssaert

Carbon emissions from the 2023 Canadian wildfires pp. 835-839

Brendan Byrne, Junjie Liu, Kevin W. Bowman, Madeleine Pascolini-Campbell, Abhishek Chatterjee, Sudhanshu Pandey, Kazuyuki Miyazaki, Guido R. Werf, Debra Wunch, Paul O. Wennberg, Coleen M. Roehl and Saptarshi Sinha

Drosophila are hosts to the first described parasitoid wasp of adult flies pp. 840-847

Logan D. Moore, Toluwanimi Chris Amuwa, Scott Richard Shaw and Matthew J. Ballinger

Origin and evolution of the bread wheat D genome pp. 848-855

Emile Cavalet-Giorsa, Andrea González-Muñoz, Naveenkumar Athiyannan, Samuel Holden, Adil Salhi, Catherine Gardener, Jesús Quiroz-Chávez, Samira M. Rustamova, Ahmed Fawzy Elkot, Mehran Patpour, Awais Rasheed, Long Mao, Evans S. Lagudah, Sambasivam K. Periyannan, Amir Sharon, Axel Himmelbach, Jochen C. Reif, Manuela Knauft, Martin Mascher, Nils Stein, Noam Chayut, Sreya Ghosh, Dragan Perovic, Alexander Putra, Ana B. Perera, Chia-Yi Hu, Guotai Yu, Hanin Ibrahim Ahmed, Konstanze D. Laquai, Luis F. Rivera, Renjie Chen, Yajun Wang, Xin Gao, Sanzhen Liu, W. John Raupp, Eric L. Olson, Jong-Yeol Lee, Parveen Chhuneja, Satinder Kaur, Peng Zhang, Robert F. Park, Yi Ding, Deng-Cai Liu, Wanlong Li, Firuza Y. Nasyrova, Jan Dvorak, Mehrdad Abbasi, Meng Li, Naveen Kumar, Wilku B. Meyer, Willem H. P. Boshoff, Brian J. Steffenson, Oadi Matny, Parva K. Sharma, Vijay K. Tiwari, Surbhi Grewal, Curtis J. Pozniak, Harmeet Singh Chawla, Jennifer Ens, Luke T. Dunning, James A. Kolmer, Gerard R. Lazo, Steven S. Xu, Yong Q. Gu, Xianyang Xu, Cristobal Uauy, Michael Abrouk, Salim Bougouffa, Gurcharn S. Brar, Brande B. H. Wulff and Simon G. Krattinger

Oligodendrocytes and myelin limit neuronal plasticity in visual cortex pp. 856-863

Wendy Xin, Megumi Kaneko, Richard H. Roth, Albert Zhang, Sonia Nocera, Jun B. Ding, Michael P. Stryker and Jonah R. Chan

Prefrontal and lateral entorhinal neurons co-dependently learn item–outcome rules pp. 864-871

Heechul Jun, Jason Y. Lee, Nicholas R. Bleza, Ayana Ichii, Jordan D. Donohue and Kei M. Igarashi

Probing plant signal processing optogenetically by two channelrhodopsins pp. 872-877

Meiqi Ding, Yang Zhou, Dirk Becker, Shang Yang, Markus Krischke, Sönke Scherzer, Jing Yu-Strzelczyk, Martin J. Mueller, Rainer Hedrich, Georg Nagel, Shiqiang Gao and Kai R. Konrad

Commensal consortia decolonize Enterobacteriaceae via ecological control pp. 878-886

Munehiro Furuichi, Takaaki Kawaguchi, Marie-Madlen Pust, Keiko Yasuma-Mitobe, Damian R. Plichta, Naomi Hasegawa, Takashi Ohya, Shakti K. Bhattarai, Satoshi Sasajima, Yoshimasa Aoto, Timur Tuganbaev, Mizuki Yaginuma, Masahiro Ueda, Nobuyuki Okahashi, Kimiko Amafuji, Yuko Kiridoshi, Kayoko Sugita, Martin Stražar, Julian Avila-Pacheco, Kerry Pierce, Clary B. Clish, Ashwin N. Skelly, Masahira Hattori, Nobuhiro Nakamoto, Silvia Caballero, Jason M. Norman, Bernat Olle, Takeshi Tanoue, Wataru Suda, Makoto Arita, Vanni Bucci, Koji Atarashi, Ramnik J. Xavier and Kenya Honda

Self-organized tissue mechanics underlie embryonic regulation pp. 887-894

Paolo Caldarelli, Alexander Chamolly, Aurélien Villedieu, Olinda Alegria-Prévot, Carole Phan, Jerome Gros and Francis Corson

Short-term post-fast refeeding enhances intestinal stemness via polyamines pp. 895-904

Shinya Imada, Saleh Khawaled, Heaji Shin, Sven W. Meckelmann, Charles A. Whittaker, Renan Oliveira Corrêa, Chiara Alquati, Yixin Lu, Guodong Tie, Dikshant Pradhan, Gizem Calibasi-Kocal, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Pia Wittenhofer, Jonathan Krystkiewicz, Oliver J. Schmitz, Jatin Roper, Marco Aurelio Ramirez Vinolo, Luigi Ricciardiello, Evan C. Lien, Matthew G. Vander Heiden, Ramesh A. Shivdasani, Chia-Wei Cheng, Alpaslan Tasdogan and Ömer H. Yilmaz

Fibrin drives thromboinflammation and neuropathology in COVID-19 pp. 905-913

Jae Kyu Ryu, Zhaoqi Yan, Mauricio Montano, Elif G. Sozmen, Karuna Dixit, Rahul K. Suryawanshi, Yusuke Matsui, Ekram Helmy, Prashant Kaushal, Sara K. Makanani, Thomas J. Deerinck, Anke Meyer-Franke, Pamela E. Rios Coronado, Troy N. Trevino, Min-Gyoung Shin, Reshmi Tognatta, Yixin Liu, Renaud Schuck, Lucas Le, Hisao Miyajima, Andrew S. Mendiola, Nikhita Arun, Brandon Guo, Taha Y. Taha, Ayushi Agrawal, Eilidh MacDonald, Oliver Aries, Aaron Yan, Olivia Weaver, Mark A. Petersen, Rosa Meza Acevedo, Maria del Pilar S. Alzamora, Reuben Thomas, Michela Traglia, Valentina L. Kouznetsova, Igor F. Tsigelny, Alexander R. Pico, Kristy Red-Horse, Mark H. Ellisman, Nevan J. Krogan, Mehdi Bouhaddou, Melanie Ott, Warner C. Greene and Katerina Akassoglou

Pathogenic hypothalamic extracellular matrix promotes metabolic disease pp. 914-922

Cait A. Beddows, Feiyue Shi, Anna L. Horton, Sagar Dalal, Ping Zhang, Chang-Chun Ling, V. Wee Yong, Kim Loh, Ellie Cho, Chris Karagiannis, Adam J. Rose, Magdalene K. Montgomery, Paul Gregorevic, Matthew J. Watt, Nicolle H. Packer, Benjamin L. Parker, Robyn M. Brown, Edward S. X. Moh and Garron T. Dodd

Mitochondrial complex I promotes kidney cancer metastasis pp. 923-931

Divya Bezwada, Luigi Perelli, Nicholas P. Lesner, Ling Cai, Bailey Brooks, Zheng Wu, Hieu S. Vu, Varun Sondhi, Daniel L. Cassidy, Stacy Kasitinon, Sherwin Kelekar, Feng Cai, Arin B. Aurora, McKenzie Patrick, Ashley Leach, Rashed Ghandour, Yuanyuan Zhang, Duyen Do, Phyllis McDaniel, Jessica Sudderth, Dennis Dumesnil, Sara House, Tracy Rosales, Alan M. Poole, Yair Lotan, Solomon Woldu, Aditya Bagrodia, Xiaosong Meng, Jeffrey A. Cadeddu, Prashant Mishra, Javier Garcia-Bermudez, Ivan Pedrosa, Payal Kapur, Kevin D. Courtney, Craig R. Malloy, Giannicola Genovese, Vitaly Margulis and Ralph J. DeBerardinis

CDK5–cyclin B1 regulates mitotic fidelity pp. 932-940

Xiao-Feng Zheng, Aniruddha Sarkar, Humphrey Lotana, Aleem Syed, Huy Nguyen, Richard G. Ivey, Jacob J. Kennedy, Jeffrey R. Whiteaker, Bartłomiej Tomasik, Kaimeng Huang, Feng Li, Alan D. D’Andrea, Amanda G. Paulovich, Kavita Shah, Alexander Spektor and Dipanjan Chowdhury

Targeted protein relocalization via protein transport coupling pp. 941-951

Christine S. C. Ng, Aofei Liu, Bianxiao Cui and Steven M. Banik

Structural insights into the high-affinity IgE receptor FcεRI complex pp. 952-959

Meijie Deng, Shuo Du, Handi Hou and Junyu Xiao

Human XPR1 structures reveal phosphate export mechanism pp. 960-967

Rui Yan, Huiwen Chen, Chuanyu Liu, Jun Zhao, Di Wu, Juquan Jiang, Jianke Gong and Daohua Jiang

UK university departments on the brink as higher-education funding crisis deepens pp. 969-971

Jack Leeming

I scale these vast trees to gather data on the effects of climate change pp. 974-974

Dave Tacon

2024, volume 633, articles 8030

Author Correction: Anti-TIGIT antibody improves PD-L1 blockade through myeloid and Treg cells pp. E1-E1

Xiangnan Guan, Ruozhen Hu, Yoonha Choi, Shyam Srivats, Barzin Y. Nabet, John Silva, Lisa McGinnis, Robert Hendricks, Katherine Nutsch, Karl L. Banta, Ellen Duong, Alexis Dunkle, Patrick S. Chang, Chia-Jung Han, Stephanie Mittman, Nandini Molden, Pallavi Daggumati, Wendy Connolly, Melissa Johnson, Delvys Rodriguez Abreu, Byoung Chul Cho, Antoine Italiano, Ignacio Gil-Bazo, Enriqueta Felip, Ira Mellman, Sanjeev Mariathasan, David S. Shames, Raymond Meng, Eugene Y. Chiang, Robert J. Johnston and Namrata S. Patil

Author Correction: Life-cycle-coupled evolution of mitosis in close relatives of animals pp. E2-E2

Hiral Shah, Marine Olivetta, Chandni Bhickta, Paolo Ronchi, Monika Trupinić, Eelco C. Tromer, Iva M. Tolić, Yannick Schwab, Omaya Dudin and Gautam Dey

Author Correction: Isolation of a methyl-reducing methanogen outside the Euryarchaeota pp. E3-E3

Kejia Wu, Lei Zhou, Guillaume Tahon, Laiyan Liu, Jiang Li, Jianchao Zhang, Fengfeng Zheng, Chengpeng Deng, Wenhao Han, Liping Bai, Lin Fu, Xiuzhu Dong, Chuanlun Zhang, Thijs J. G. Ettema, Diana Z. Sousa and Lei Cheng

Publisher Correction: Elastic films of single-crystal two-dimensional covalent organic frameworks pp. E4-E4

Yonghang Yang, Baokun Liang, Jakob Kreie, Mike Hambsch, Zihao Liang, Cheng Wang, Senhe Huang, Xin Dong, Li Gong, Chaolun Liang, Dongyang Lou, Zhipeng Zhou, Jiaxing Lu, Yang Yang, Xiaodong Zhuang, Haoyuan Qi, Ute Kaiser, Stefan C. B. Mannsfeld, Wei Liu, Armin Gölzhäuser and Zhikun Zheng

Rise of ChatGPT and other tools raises major questions for research pp. S5-S5

Simon Baker

Rage against machine learning driven by profit pp. S6-S9

Brian Owens

Why AI might be a game-changer for Africa pp. S12-S14

Rachel Nuwer

Artificial intelligence laws in the US states are feeling the weight of corporate lobbying pp. S15-S15

Emmie Hine

Can AI be used to assess research quality? pp. S18-S20

Jackson Ryan

Stop delaying action on antimicrobial resistance — it is achievable and affordable pp. 495-495

Ramanan Laxminarayan

US and China inch towards renewing science-cooperation pact — despite tensions pp. 499-500

Natasha Gilbert and Smriti Mallapaty

World’s first whole-eye transplant: the innovations that made it possible pp. 500-501

Julian Nowogrodzki

New virus-genome website seeks to make sharing sequences easy and fair pp. 501-502

Smriti Mallapaty

How to change people’s minds about climate change: what the science says pp. 502-503

Alix Soliman

Why some women enter menopause early — and how that could affect their cancer risk pp. 503-504

Heidi Ledford

First private spacewalk a success! What the SpaceX mission means for science pp. 504-505

Michael Greshko

Fur farming a ‘viral highway’ that could spark next pandemic, say scientists pp. 506-506

Smriti Mallapaty

Doctors cured her sickle-cell disease. So why is she still in pain? pp. 508-511

Heidi Ledford

The UK’s $1-billion bet to create technologies that change the world pp. 512-514

Nisha Gaind

When physicists strove for peace: past lessons for our uncertain times pp. 515-517

Roberto Lalli and Jaume Navarro

The Burning Earth: how conquest and carnage have decimated landscapes worldwide pp. 518-519

Josie Glausiusz

Tackling antimicrobial resistance needs a tailored approach — four specialists weigh in pp. 521-524

Senjuti Saha, Ana Cristina Gales, Iruka N. Okeke and Nour Shamas

UN Pact for the Future: Scientists must step up to accelerate sustainability goals pp. 525-525

Terrence Forrester

To combat antimicrobial resistance, invest in test-to-treat strategies pp. 525-525

Rachel A. McKendry, Elliott Rogers, Mervyn Singer and Colin S. Brown

AI model collapse might be prevented by studying human language transmission pp. 525-525

Kenny Smith, Simon Kirby, Shangmin Guo and Thomas L. Griffiths

My identity was stolen by a predatory conference pp. 525-525

Tin Wui Wong

Magnetic whirlpools creep and flow in response to emergent electrodynamics pp. 527-528

Yingying Wu

Skull bones harbour immune cells that are poised to target brain tumours pp. 528-529

Juyeun Lee and Justin D. Lathia

Menopause age shaped by genes that influence mutation risk pp. 530-531

Anne Goriely

Quarks show that quantum entanglement holds at high energies pp. 531-532

Martin Hentschinski

Thread, read, rewind, repeat: towards using nanopores for protein sequencing pp. 533-534

Aleksei Aksimentiev

Long-lasting heart-failure treatment could be a game-changer pp. 534-535

John C. Burnett

Black hole jets on the scale of the cosmic web pp. 537-541

Martijn S. S. L. Oei, Martin J. Hardcastle, Roland Timmerman, Aivin R. D. J. G. I. B. Gast, Andrea Botteon, Antonio C. Rodriguez, Daniel Stern, Gabriela Calistro Rivera, Reinout J. Weeren, Huub J. A. Röttgering, Huib T. Intema, Francesco Gasperin and S. G. Djorgovski

Signatures of magnetism control by flow of angular momentum pp. 548-553

L. Chen, Y. Sun, S. Mankovsky, T. N. G. Meier, M. Kronseder, C. Sun, A. Orekhov, H. Ebert, D. Weiss and C. H. Back

Dynamic transition and Galilean relativity of current-driven skyrmions pp. 554-559

Max T. Birch, Ilya Belopolski, Yukako Fujishiro, Minoru Kawamura, Akiko Kikkawa, Yasujiro Taguchi, Max Hirschberger, Naoto Nagaosa and Yoshinori Tokura

Linear symmetric self-selecting 14-bit kinetic molecular memristors pp. 560-566

Deepak Sharma, Santi Prasad Rath, Bidyabhusan Kundu, Anil Korkmaz, Harivignesh S, Damien Thompson, Navakanta Bhat, Sreebrata Goswami, R. Stanley Williams and Sreetosh Goswami

Two-dimensional-lattice-confined single-molecule-like aggregates pp. 567-574

Kang Wang, Zih-Yu Lin, Angana De, Conrad A. Kocoj, Wenhao Shao, Hanjun Yang, Zehua He, Aidan H. Coffey, Colton B. Fruhling, Yuanhao Tang, Dharini Varadharajan, Chenhui Zhu, Yong Sheng Zhao, Alexandra Boltasseva, Vladimir M. Shalaev, Peijun Guo, Brett M. Savoie and Letian Dou

A polymer-like ultrahigh-strength metal alloy pp. 575-581

Zhizhi Xu, Yuanchao Ji, Chang Liu, Liqiang He, Hui Zhao, Ye Yuan, Yu Qian, Jin Cui, Andong Xiao, Wenjia Wang, Yang Yang, Tianyu Ma and Xiaobing Ren

A climate threshold for ocean deoxygenation during the Early Cretaceous pp. 582-586

Kohen W. Bauer, N. Ryan McKenzie, Chris T. L. Cheung, Gabriele Gambacorta, Cinzia Bottini, Adam R. Nordsvan, Elisabetta Erba and Sean A. Crowe

Decoding drivers of carbon flux attenuation in the oceanic biological pump pp. 587-593

M. Bressac, E. C. Laurenceau-Cornec, F. Kennedy, A. E. Santoro, N. L. Paul, N. Briggs, F. Carvalho and P. W. Boyd

Observation-constrained projections reveal longer-than-expected dry spells pp. 594-600

Irina Y. Petrova, Diego G. Miralles, Florent Brient, Markus G. Donat, Seung-Ki Min, Yeon-Hee Kim and Margot Bador

Three-dimensional wave breaking pp. 601-607

M. L. McAllister, S. Draycott, R. Calvert, T. Davey, F. Dias and T. S. Bremer

Genetic links between ovarian ageing, cancer risk and de novo mutation rates pp. 608-614

Stasa Stankovic, Saleh Shekari, Qin Qin Huang, Eugene J. Gardner, Erna V. Ivarsdottir, Nick D. L. Owens, Nasim Mavaddat, Ajuna Azad, Gareth Hawkes, Katherine A. Kentistou, Robin N. Beaumont, Felix R. Day, Yajie Zhao, Hakon Jonsson, Thorunn Rafnar, Vinicius Tragante, Gardar Sveinbjornsson, Asmundur Oddsson, Unnur Styrkarsdottir, Julius Gudmundsson, Simon N. Stacey, Daniel F. Gudbjartsson, Kitale Kennedy, Andrew R. Wood, Michael N. Weedon, Ken K. Ong, Caroline F. Wright, Eva R. Hoffmann, Patrick Sulem, Matthew E. Hurles, Katherine S. Ruth, Hilary C. Martin, Kari Stefansson, John R. B. Perry and Anna Murray

Thermal infrared directs host-seeking behaviour in Aedes aegypti mosquitoes pp. 615-623

Avinash Chandel, Nicolas A. DeBeaubien, Anindya Ganguly, Geoff T. Meyerhof, Andreas A. Krumholz, Jiangqu Liu, Vincent L. Salgado and Craig Montell

Frontostriatal salience network expansion in individuals in depression pp. 624-633

Charles J. Lynch, Immanuel G. Elbau, Tommy Ng, Aliza Ayaz, Shasha Zhu, Danielle Wolk, Nicola Manfredi, Megan Johnson, Megan Chang, Jolin Chou, Indira Summerville, Claire Ho, Maximilian Lueckel, Hussain Bukhari, Derrick Buchanan, Lindsay W. Victoria, Nili Solomonov, Eric Goldwaser, Stefano Moia, Cesar Caballero-Gaudes, Jonathan Downar, Fidel Vila-Rodriguez, Zafiris J. Daskalakis, Daniel M. Blumberger, Kendrick Kay, Amy Aloysi, Evan M. Gordon, Mahendra T. Bhati, Nolan Williams, Jonathan D. Power, Benjamin Zebley, Logan Grosenick, Faith M. Gunning and Conor Liston

Cellular communities reveal trajectories of brain ageing and Alzheimer’s disease pp. 634-645

Gilad Sahar Green, Masashi Fujita, Hyun-Sik Yang, Mariko Taga, Anael Cain, Cristin McCabe, Natacha Comandante-Lou, Charles C. White, Anna K. Schmidtner, Lu Zeng, Alina Sigalov, Yangling Wang, Aviv Regev, Hans-Ulrich Klein, Vilas Menon, David A. Bennett, Naomi Habib and Philip L. Jager

Growth of complete ammonia oxidizers on guanidine pp. 646-653

Marton Palatinszky, Craig W. Herbold, Christopher J. Sedlacek, Dominic Pühringer, Katharina Kitzinger, Andrew T. Giguere, Kenneth Wasmund, Per H. Nielsen, Morten K. D. Dueholm, Nico Jehmlich, Richard Gruseck, Anton Legin, Julius Kostan, Nesrete Krasnici, Claudia Schreiner, Johanna Palmetzhofer, Thilo Hofmann, Michael Zumstein, Kristina Djinović-Carugo, Holger Daims and Michael Wagner

Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone pp. 654-661

Michael E. Dunn, Aaron Kithcart, Jee Hae Kim, Andre Jo-Hao Ho, Matthew C. Franklin, Annabel Romero Hernandez, Jan Hoon, Wouter Botermans, Jonathan Meyer, Ximei Jin, Dongqin Zhang, Justin Torello, Daniel Jasewicz, Vishal Kamat, Elena Garnova, Nina Liu, Michael Rosconi, Hao Pan, Satyajit Karnik, Michael E. Burczynski, Wenjun Zheng, Ashique Rafique, Jonas B. Nielsen, Tanima De, Niek Verweij, Anita Pandit, Adam Locke, Naga Chalasani, Olle Melander, Tae-Hwi Schwantes-An, Aris Baras, Luca A. Lotta, Bret J. Musser, Jason Mastaitis, Kishor B. Devalaraja-Narashimha, Andrew J. Rankin, Tammy Huang, Gary Herman, William Olson, Andrew J. Murphy, George D. Yancopoulos, Benjamin A. Olenchock and Lori Morton

Multi-pass, single-molecule nanopore reading of long protein strands pp. 662-669

Keisuke Motone, Daphne Kontogiorgos-Heintz, Jasmine Wee, Kyoko Kurihara, Sangbeom Yang, Gwendolin Roote, Oren E. Fox, Yishu Fang, Melissa Queen, Mattias Tolhurst, Nicolas Cardozo, Miten Jain and Jeff Nivala

Fate induction in CD8 CAR T cells through asymmetric cell division pp. 670-677

Casey S. Lee, Sisi Chen, Corbett T. Berry, Andre R. Kelly, Patrick J. Herman, Sangwook Oh, Roddy S. O’Connor, Aimee S. Payne and Christoph T. Ellebrecht

Titration of RAS alters senescent state and influences tumour initiation pp. 678-685

Adelyne S. L. Chan, Haoran Zhu, Masako Narita, Liam D. Cassidy, Andrew R. J. Young, Camino Bermejo-Rodriguez, Aleksandra T. Janowska, Hung-Chang Chen, Sarah Gough, Naoki Oshimori, Lars Zender, Sarah J. Aitken, Matthew Hoare and Masashi Narita

Embryonic genome instability upon DNA replication timing program emergence pp. 686-694

Saori Takahashi, Hirohisa Kyogoku, Takuya Hayakawa, Hisashi Miura, Asami Oji, Yoshiko Kondo, Shin-ichiro Takebayashi, Tomoya S. Kitajima and Ichiro Hiratani

Mapping glycoprotein structure reveals Flaviviridae evolutionary history pp. 695-703

Jonathon C. O. Mifsud, Spyros Lytras, Michael R. Oliver, Kamilla Toon, Vincenzo A. Costa, Edward C. Holmes and Joe Grove

The hepatitis C virus envelope protein complex is a dimer of heterodimers pp. 704-709

Elias Honerød Augestad, Christina Holmboe Olesen, Christina Grønberg, Andreas Soerensen, Rodrigo Velázquez-Moctezuma, Margherita Fanalista, Jens Bukh, Kaituo Wang, Pontus Gourdon and Jannick Prentoe

Birth of protein folds and functions in the virome pp. 710-717

Jason Nomburg, Erin E. Doherty, Nathan Price, Daniel Bellieny-Rabelo, Yong K. Zhu and Jennifer A. Doudna

NAC guides a ribosomal multienzyme complex for nascent protein processing pp. 718-724

Alfred M. Lentzsch, Denis Yudin, Martin Gamerdinger, Sowmya Chandrasekar, Laurenz Rabl, Alain Scaiola, Elke Deuerling, Nenad Ban and Shu-ou Shan

How can I publish open access when I can’t afford the fees? pp. 725-726

Nikki Forrester

Forget ChatGPT: why researchers now run small AIs on their laptops pp. 728-729

Matthew Hutson

I fire darts at whales to help track their movements pp. 732-732

Esme Hedley

2024, volume 633, articles 8029

Europe sidelines Alzheimer’s drug: lessons must be learnt pp. 255-255

Henrik Zetterberg

The race to save fossils exposed by Brazil’s record-setting floods pp. 259-260

Meghie Rodrigues

Publishing nightmare: a researcher’s quest to keep his own work from being plagiarized pp. 260-262

Dan Garisto

‘Nuclear clock’ breakthrough paves the way for super-precise timekeeping pp. 262-263

Elizabeth Gibney

Spectacular stars over Stonehenge and more — August’s best science images pp. 263-263

Helena Kudiabor

Gender-affirming therapy reshapes the immune systems of trans men pp. 264-265

Saima Sidik

Found: a brain-wiring pattern linked to depression pp. 265-266

Sara Reardon

Researchers built an ‘AI Scientist’ — what can it do? pp. 266-266

Davide Castelvecchi

Human embryo models are getting more realistic — raising ethical questions pp. 268-271

Smriti Mallapaty

Why does heart disease affect so many young South Asians? pp. 272-274

Anil Oza

How influencers and algorithms mobilize propaganda — and distort reality pp. 275-277

Sander van der Linden

Consider the finches: Books in brief pp. 277-277

Andrew Robinson

Data on SDGs are riddled with gaps. Citizens can help pp. 279-281

Yongyi Min, Haoyi Chen and Francesca Perucci

Wildfires are spreading fast in Canada — we must strengthen forests for the future pp. 282-285

Christopher Mulverhill, Nicholas C. Coops, Yan Boulanger, Kira M. Hoffman, Amy Cardinal Christianson, Lori D. Daniels, Maude Flamand-Hubert, Amy R. Wotherspoon and Alexis Achim

The pharmaceutical industry must embrace synthetic alternatives to horseshoe-crab blood pp. 286-286

Tim Cernak and Lawrence Niles

Artificial intelligence can help to make animal research redundant pp. 286-286

Calvin Drakos, Vineesha Manimangalam, Christina Burns and Ozlem Equils

Update regulator guidance to show that animal research really is no longer king pp. 286-286

Lindsay Marshall, Rebecca Simmons and Greg Sower

Energy storage overcapacity can cause power system instability and blackouts, too pp. 286-286

Bo Yang and Zunlian Zhao

Bioprospecting marine microbial genomes to improve biotechnology pp. 287-288

A. Murat Eren and Tom O. Delmont

Swirling star bubbles offer a glimpse of the Sun’s future pp. 288-289

Claudia Paladini

Rapa Nui’s population history rewritten using ancient DNA pp. 290-291

Stephan Schiffels and Kathrin Nägele

Future optoelectronics unlocked by ‘doping’ strategy pp. 291-292

Fangyuan Jiang and David S. Ginger

People who lack the immune protein TNF can still fight infection pp. 293-294

Charlie J. Pyle and David M. Tobin

The emerging view on the origin and early evolution of eukaryotic cells pp. 295-305

Julian Vosseberg, Jolien J. E. Hooff, Stephan Köstlbacher, Kassiani Panagiotou, Daniel Tamarit and Thijs J. G. Ettema

Extreme solar storms and the quest for exact dating with radiocarbon pp. 306-317

T. J. Heaton, E. Bard, A. Bayliss, M. Blaauw, C. Bronk Ramsey, P. J. Reimer, C. S. M. Turney and I. Usoskin

Spectroscopic confirmation of two luminous galaxies at a redshift of 14 pp. 318-322

Stefano Carniani, Kevin Hainline, Francesco D’Eugenio, Daniel J. Eisenstein, Peter Jakobsen, Joris Witstok, Benjamin D. Johnson, Jacopo Chevallard, Roberto Maiolino, Jakob M. Helton, Chris Willott, Brant Robertson, Stacey Alberts, Santiago Arribas, William M. Baker, Rachana Bhatawdekar, Kristan Boyett, Andrew J. Bunker, Alex J. Cameron, Phillip A. Cargile, Stéphane Charlot, Mirko Curti, Emma Curtis-Lake, Eiichi Egami, Giovanna Giardino, Kate Isaak, Zhiyuan Ji, Gareth C. Jones, Nimisha Kumari, Michael V. Maseda, Eleonora Parlanti, Pablo G. Pérez-González, Tim Rawle, George Rieke, Marcia Rieke, Bruno Rodríguez Pino, Aayush Saxena, Jan Scholtz, Renske Smit, Fengwu Sun, Sandro Tacchella, Hannah Übler, Giacomo Venturi, Christina C. Williams and Christopher N. A. Willmer

One month convection timescale on the surface of a giant evolved star pp. 323-326

Wouter Vlemmings, Theo Khouri, Behzad Bojnordi Arbab, Elvire Beck and Matthias Maercker

Chandrayaan-3 APXS elemental abundance measurements at lunar high latitude pp. 327-331

Santosh V. Vadawale, N. P. S. Mithun, M. Shanmugam, Amit Basu Sarbadhikari, Rishitosh K. Sinha, Megha Bhatt, S. Vijayan, Neeraj Srivastava, Anil D. Shukla, S. V. S. Murty, Anil Bhardwaj, Y. B. Acharya, Arpit R. Patel, Hiteshkumar L. Adalaja, C. S. Vaishnava, B. S. Bharath Saiguhan, Nishant Singh, Sushil Kumar, Deepak Kumar Painkra, Yash Srivastava, Varsha M. Nair, Tinkal Ladiya, Shiv Kumar Goyal, Neeraj K. Tiwari, Shyama Narendranath, Netra S. Pillai, Arup Kumar Hait, Aaditya Patinge, Abhishek Kumar, Neeraj Satya, Vivek R. Subramanian, Sonal G. Navle, R. G. Venkatesh, Lalitha Abraham, K. Suresh and Amitabh

Two-axis twisting using Floquet-engineered XYZ spin models with polar molecules pp. 332-337

Calder Miller, Annette N. Carroll, Junyu Lin, Henrik Hirzler, Haoyang Gao, Hengyun Zhou, Mikhail D. Lukin and Jun Ye

Observing the two-dimensional Bose glass in an optical quasicrystal pp. 338-343

Jr-Chiun Yu, Shaurya Bhave, Lee Reeve, Bo Song and Ulrich Schneider

Controllable p- and n-type behaviours in emissive perovskite semiconductors pp. 344-350

Wentao Xiong, Weidong Tang, Gan Zhang, Yichen Yang, Yangning Fan, Ke Zhou, Chen Zou, Baodan Zhao and Dawei Di

Closed-loop transfer enables artificial intelligence to yield chemical knowledge pp. 351-358

Nicholas H. Angello, David M. Friday, Changhyun Hwang, Seungjoo Yi, Austin H. Cheng, Tiara C. Torres-Flores, Edward R. Jira, Wesley Wang, Alán Aspuru-Guzik, Martin D. Burke, Charles M. Schroeder, Ying Diao and Nicholas E. Jackson

Two-dimensional perovskitoids enhance stability in perovskite solar cells pp. 359-364

Cheng Liu, Yi Yang, Hao Chen, Ioannis Spanopoulos, Abdulaziz S. R. Bati, Isaiah W. Gilley, Jianhua Chen, Aidan Maxwell, Badri Vishal, Robert P. Reynolds, Taylor E. Wiggins, Zaiwei Wang, Chuying Huang, Jared Fletcher, Yuan Liu, Lin X. Chen, Stefaan Wolf, Bin Chen, Ding Zheng, Tobin J. Marks, Antonio Facchetti, Edward H. Sargent and Mercouri G. Kanatzidis

Neoarchaean oxygen-based nitrogen cycle en route to the Great Oxidation Event pp. 365-370

Alice Pellerin, Christophe Thomazo, Magali Ader, Camille Rossignol, Eric Siciliano Rego, Vincent Busigny and Pascal Philippot

Global marine microbial diversity and its potential in bioprospecting pp. 371-379

Jianwei Chen, Yangyang Jia, Ying Sun, Kun Liu, Changhao Zhou, Chuan Liu, Denghui Li, Guilin Liu, Chengsong Zhang, Tao Yang, Lei Huang, Yunyun Zhuang, Dazhi Wang, Dayou Xu, Qiaoling Zhong, Yang Guo, Anduo Li, Inge Seim, Ling Jiang, Lushan Wang, Simon Ming Yuen Lee, Yujing Liu, Dantong Wang, Guoqiang Zhang, Shanshan Liu, Xiaofeng Wei, Zhen Yue, Shanmin Zheng, Xuechun Shen, Sen Wang, Chen Qi, Jing Chen, Chen Ye, Fang Zhao, Jun Wang, Jie Fan, Baitao Li, Jiahui Sun, Xiaodong Jia, Zhangyong Xia, He Zhang, Junnian Liu, Yue Zheng, Xin Liu, Jian Wang, Huanming Yang, Karsten Kristiansen, Xun Xu, Thomas Mock, Shengying Li, Wenwei Zhang and Guangyi Fan

Teosinte Pollen Drive guides maize diversification and domestication by RNAi pp. 380-388

Benjamin Berube, Evan Ernst, Jonathan Cahn, Benjamin Roche, Cristiane Santis Alves, Jason Lynn, Armin Scheben, Daniel Grimanelli, Adam Siepel, Jeffrey Ross-Ibarra, Jerry Kermicle and Robert A. Martienssen

Ancient Rapanui genomes reveal resilience and pre-European contact with the Americas pp. 389-397

J. Víctor Moreno-Mayar, Bárbara Sousa da Mota, Tom Higham, Signe Klemm, Moana Gorman Edmunds, Jesper Stenderup, Miren Iraeta-Orbegozo, Véronique Laborde, Evelyne Heyer, Francisco Torres Hochstetter, Martin Friess, Morten E. Allentoft, Hannes Schroeder, Olivier Delaneau and Anna-Sapfo Malaspinas

Cooperative thalamocortical circuit mechanism for sensory prediction errors pp. 398-406

Shohei Furutachi, Alexis D. Franklin, Andreea M. Aldea, Thomas D. Mrsic-Flogel and Sonja B. Hofer

Stem cells tightly regulate dead cell clearance to maintain tissue fitness pp. 407-416

Katherine S. Stewart, Merve Deniz Abdusselamoglu, Matthew T. Tierney, Anita Gola, Yun Ha Hur, Kevin A. U. Gonzales, Shaopeng Yuan, Alain R. Bonny, Yihao Yang, Nicole R. Infarinato, Christopher J. Cowley, John M. Levorse, Hilda Amalia Pasolli, Sourav Ghosh, Carla V. Rothlin and Elaine Fuchs

Tuberculosis in otherwise healthy adults with inherited TNF deficiency pp. 417-425

Andrés A. Arias, Anna-Lena Neehus, Masato Ogishi, Vincent Meynier, Adam Krebs, Tomi Lazarov, Angela M. Lee, Carlos A. Arango-Franco, Rui Yang, Julio Orrego, Melissa Corcini Berndt, Julian Rojas, Hailun Li, Darawan Rinchai, Lucia Erazo-Borrás, Ji Eun Han, Bethany Pillay, Khoren Ponsin, Matthieu Chaldebas, Quentin Philippot, Jonathan Bohlen, Jérémie Rosain, Tom Voyer, Till Janotte, Krishnajina Amarajeeva, Camille Soudée, Marion Brollo, Katja Wiegmann, Quentin Marquant, Yoann Seeleuthner, Danyel Lee, Candice Lainé, Doreen Kloos, Rasheed Bailey, Paul Bastard, Narelle Keating, Franck Rapaport, Taushif Khan, Marcela Moncada-Vélez, María Camila Carmona, Catalina Obando, Jesús Alvarez, Juan Carlos Cataño, Larry Luber Martínez-Rosado, Juan P. Sanchez, Manuela Tejada-Giraldo, Anne-Sophie L’Honneur, María L. Agudelo, Lizet J. Perez-Zapata, Diana M. Arboleda, Juan Fernando Alzate, Felipe Cabarcas, Alejandra Zuluaga, Simon J. Pelham, Armin Ensser, Monika Schmidt, Margarita M. Velásquez-Lopera, Emmanuelle Jouanguy, Anne Puel, Martin Krönke, Stefano Ghirardello, Alessandro Borghesi, Susanta Pahari, Bertrand Boisson, Stefania Pittaluga, Cindy S. Ma, Jean-François Emile, Luigi D. Notarangelo, Stuart G. Tangye, Nico Marr, Nico Lachmann, Hélène Salvator, Larry S. Schlesinger, Peng Zhang, Michael S. Glickman, Carl F. Nathan, Frédéric Geissmann, Laurent Abel, José Luis Franco, Jacinta Bustamante, Jean-Laurent Casanova and Stéphanie Boisson-Dupuis

Pathogenicity and transmissibility of bovine H5N1 influenza virus pp. 426-432

Amie J. Eisfeld, Asim Biswas, Lizheng Guan, Chunyang Gu, Tadashi Maemura, Sanja Trifkovic, Tong Wang, Lavanya Babujee, Randall Dahn, Peter J. Halfmann, Tera Barnhardt, Gabriele Neumann, Yasuo Suzuki, Alexis Thompson, Amy K. Swinford, Kiril M. Dimitrov, Keith Poulsen and Yoshihiro Kawaoka

DNA-sensing inflammasomes cause recurrent atherosclerotic stroke pp. 433-441

Jiayu Cao, Stefan Roth, Sijia Zhang, Anna Kopczak, Samira Mami, Yaw Asare, Marios K. Georgakis, Denise Messerer, Amit Horn, Ruth Shemer, Charlene Jacqmarcq, Audrey Picot, Jack P. Green, Christina Schlegl, Xinghai Li, Lukas Tomas, Alexander Dutsch, Thomas G. Liman, Matthias Endres, Saskia R. Wernsdorf, Christina Fürle, Olga Carofiglio, Jie Zhu, David Brough, Veit Hornung, Martin Dichgans, Denis Vivien, Christian Schulz, Yuval Dor, Steffen Tiedt, Hendrik B. Sager, Gerrit M. Grosse and Arthur Liesz

Recognition and control of neutrophil extracellular trap formation by MICL pp. 442-450

Mariano Malamud, Lauren Whitehead, Alasdair McIntosh, Fabio Colella, Anke J. Roelofs, Takato Kusakabe, Ivy M. Dambuza, Annie Phillips-Brookes, Fabián Salazar, Federico Perez, Romey Shoesmith, Przemyslaw Zakrzewski, Emily A. Sey, Cecilia Rodrigues, Petruta L. Morvay, Pierre Redelinghuys, Tina Bedekovic, Maria J. G. Fernandes, Ruqayyah Almizraq, Donald R. Branch, Borko Amulic, Jamie Harvey, Diane Stewart, Raif Yuecel, Delyth M. Reid, Alex McConnachie, Matthew C. Pickering, Marina Botto, Iliyan D. Iliev, Iain B. McInnes, Cosimo Bari, Janet A. Willment and Gordon D. Brown

Glycosphingolipid synthesis mediates immune evasion in KRAS-driven cancer pp. 451-458

Mariluz Soula, Gokhan Unlu, Rachel Welch, Aleksey Chudnovskiy, Beste Uygur, Vyom Shah, Hanan Alwaseem, Paul Bunk, Vishvak Subramanyam, Hsi-Wen Yeh, Artem Khan, Søren Heissel, Hani Goodarzi, Gabriel D. Victora, Semir Beyaz and Kıvanç Birsoy

Visualizing chaperonin function in situ by cryo-electron tomography pp. 459-464

Jonathan Wagner, Alonso I. Carvajal, Andreas Bracher, Florian Beck, William Wan, Stefan Bohn, Roman Körner, Wolfgang Baumeister, Ruben Fernandez-Busnadiego and F. Ulrich Hartl

Structural basis for the activity of the type VII CRISPR–Cas system pp. 465-472

Jie Yang, Xuzichao Li, Qiuqiu He, Xiaoshen Wang, Jingjing Tang, Tongyao Wang, Yi Zhang, Feiyang Yu, Shuqin Zhang, Zhikun Liu, Lingling Zhang, Fumeng Liao, Hang Yin, Haiyan Zhao, Zengqin Deng and Heng Zhang

Substrate binding and inhibition mechanism of norepinephrine transporter pp. 473-479

Wenming Ji, Anran Miao, Kai Liang, Jiameng Liu, Yuhan Qi, Yue Zhou, Xinli Duan, Jixue Sun, Lipeng Lai and Jing-Xiang Wu

The human costs of the research-assessment culture pp. 481-484

Rachel Brazil

I make fake eyes for those who need them pp. 486-486

Linda Nordling

2024, volume 633, articles 8028

Guide, don’t hide: reprogramming learning in the wake of AI pp. S1-S3

Monique Brouillette

African scientists must not be priced out of mental-health research pp. 9-9

Vivien Chebii

Why the next pandemic could come from the Arctic — and what to do about it pp. 10-10

Christian Sonne

Exclusive: the papers that most heavily cite retracted studies pp. 13-15

Richard Van Noorden and Miryam Naddaf

AI analysed 1,500 policies to cut emissions. These ones worked pp. 15-16

Xiaoying You

Mpox is spreading rapidly. Here are the questions researchers are racing to answer pp. 16-17

Sara Reardon

‘I hope I get the opportunity to fly’: Meet Paralympian-turned-astronaut John McFall pp. 18-19

Helena Kudiabor

Stone Age builders had engineering savvy, finds study of 6,000-year-old monument pp. 19-20

Roff Smith

What accelerates brain ageing? This AI ‘brain clock’ points to answers pp. 20-20

Julian Nowogrodzki

A day in the life of the world’s fastest supercomputer pp. 22-25

Sophia Chen

The biology of smell is a mystery — AI is helping to solve it pp. 26-29

Kerri Smith

Why repairing forests is not just about planting trees pp. 30-31

Debraj Manna

No basis for claim that 80% of biodiversity is found in Indigenous territories pp. 32-35

Álvaro Fernández-Llamazares, Julia E. Fa, Dan Brockington, Eduardo S. Brondízio, Joji Cariño, Esteve Corbera, Maurizio Farhan Ferrari, Daniel Kobei, Pernilla V, Guadalupe Yesenia H. Márquez, Zsolt Molnár, Helen Tugendhat and Stephen T. Garnett

International whaling convention needs boosting, not dismantling pp. 36-36

Chris Wold

Don’t dismiss the Montreal ozone-depletion protocol as a ‘zombie’ pp. 36-36

Durwood Zaelke and Paul Bledsoe

To tackle social-media harms, mandate data access for researchers pp. 36-36

Steve Rathje

To conserve biodiversity, create spaces where natural selection is allowed free rein pp. 36-36

Bruno Fady and Magda Bou Dagher Kharrat

Waste management won’t solve the plastics problem — we need to cut consumption pp. 37-38

Matthew MacLeod

The immune system of trans men reveals how hormones shape immunity pp. 38-40

Margaret M. McCarthy

LLMs produce racist output when prompted in African American English pp. 40-41

Su Lin Blodgett and Zeerak Talat

Breast cancer blocked by multiple natural lines of defence pp. 42-43

Biancastella Cereser

Countdown to a nuclear clock pp. 43-45

Adriana Pálffy and José R. Crespo López-Urrutia

The heart is put at risk of rupture by cells bordering damaged tissue pp. 45-46

Kory Lavine

Gravitational instability in a planet-forming disk pp. 58-62

Jessica Speedie, Ruobing Dong, Cassandra Hall, Cristiano Longarini, Benedetta Veronesi, Teresa Paneque-Carreño, Giuseppe Lodato, Ya-Wen Tang, Richard Teague and Jun Hashimoto

Frequency ratio of the 229mTh nuclear isomeric transition and the 87Sr atomic clock pp. 63-70

Chuankun Zhang, Tian Ooi, Jacob S. Higgins, Jack F. Doyle, Lars Wense, Kjeld Beeks, Adrian Leitner, Georgy A. Kazakov, Peng Li, Peter G. Thirolf, Thorsten Schumm and Jun Ye

Signatures of hybridization of multiple Majorana zero modes in a vortex pp. 71-76

Tengteng Liu, Chun Yu Wan, Hao Yang, Yujun Zhao, Bangjin Xie, Weiyan Zheng, Zhaoxia Yi, Dandan Guan, Shiyong Wang, Hao Zheng, Canhua Liu, Liang Fu, Junwei Liu, Yaoyi Li and Jinfeng Jia

Long-lived isospin excitations in magic-angle twisted bilayer graphene pp. 77-82

Tian Xie, Siyuan Xu, Zhiyu Dong, Zhiyuan Cui, Yunbo Ou, Melike Erdi, Kenji Watanabe, Takashi Taniguchi, Seth A. Tongay, Leonid S. Levitov and Chenhao Jin

Photoredox phase engineering of transition metal dichalcogenides pp. 83-89

Juhwan Lim, Jung-In Lee, Ye Wang, Nicolas Gauriot, Ebin Sebastian, Manish Chhowalla, Christoph Schnedermann and Akshay Rao

Catalytic asymmetric synthesis of meta benzene isosteres pp. 90-95

Mingkai Zhang, Matthew Chapman, Bhagyesh R. Sarode, Bingcong Xiong, Hao Liang, James K. Chen, Eranthie Weerapana and James P. Morken

Effective realization of abatement measures can reduce HFC-23 emissions pp. 96-100

Dominique Rust, Martin K. Vollmer, Stephan Henne, Arnoud Frumau, Pim Bulk, Arjan Hensen, Kieran M. Stanley, Renato Zenobi, Lukas Emmenegger and Stefan Reimann

A local-to-global emissions inventory of macroplastic pollution pp. 101-108

Joshua W. Cottom, Ed Cook and Costas A. Velis

Highly variable magmatic accretion at the ultraslow-spreading Gakkel Ridge pp. 109-113

Tao Zhang, Jiabiao Li, Xiongwei Niu, Weiwei Ding, Yinxia Fang, Jian Lin, Yejian Wang, Caicai Zha, Pingchuan Tan, Fansheng Kong, Jie Chen, Xiaodong Wei, Jianggu Lu, Jérôme Dyment and Jason P. Morgan

Multi-habitat landscapes are more diverse and stable with improved function pp. 114-119

Talya D. Hackett, Alix M. C. Sauve, Kate P. Maia, Daniel Montoya, Nancy Davies, Rose Archer, Simon G. Potts, Jason M. Tylianakis, Ian P. Vaughan and Jane Memmott

Organ systems of a Cambrian euarthropod larva pp. 120-126

Martin R. Smith, Emma J. Long, Alavya Dhungana, Katherine J. Dobson, Jie Yang and Xiguang Zhang

The genomic landscape of 2,023 colorectal cancers pp. 127-136

Alex J. Cornish, Andreas J. Gruber, Ben Kinnersley, Daniel Chubb, Anna Frangou, Giulio Caravagna, Boris Noyvert, Eszter Lakatos, Henry M. Wood, Steve Thorn, Richard Culliford, Claudia Arnedo-Pac, Jacob Househam, William Cross, Amit Sud, Philip Law, Maire Ni Leathlobhair, Aliah Hawari, Connor Woolley, Kitty Sherwood, Nathalie Feeley, Güler Gül, Juan Fernandez-Tajes, Luis Zapata, Ludmil B. Alexandrov, Nirupa Murugaesu, Alona Sosinsky, Jonathan Mitchell, Nuria Lopez-Bigas, Philip Quirke, David N. Church, Ian P. M. Tomlinson, Andrea Sottoriva, Trevor A. Graham, David C. Wedge and Richard S. Houlston

Prognostic genome and transcriptome signatures in colorectal cancers pp. 137-146

Luís Nunes, Fuqiang Li, Meizhen Wu, Tian Luo, Klara Hammarström, Emma Torell, Ingrid Ljuslinder, Artur Mezheyeuski, Per-Henrik Edqvist, Anna Löfgren-Burström, Carl Zingmark, Sofia Edin, Chatarina Larsson, Lucy Mathot, Erik Osterman, Emerik Osterlund, Viktor Ljungström, Inês Neves, Nicole Yacoub, Unnur Guðnadóttir, Helgi Birgisson, Malin Enblad, Fredrik Ponten, Richard Palmqvist, Xun Xu, Mathias Uhlén, Kui Wu, Bengt Glimelius, Cong Lin and Tobias Sjöblom

AI generates covertly racist decisions about people based on their dialect pp. 147-154

Valentin Hofmann, Pratyusha Ria Kalluri, Dan Jurafsky and Sharese King

Immune system adaptation during gender-affirming testosterone treatment pp. 155-164

Tadepally Lakshmikanth, Camila Consiglio, Fabian Sardh, Rikard Forlin, Jun Wang, Ziyang Tan, Hugo Barcenilla, Lucie Rodriguez, Jamie Sugrue, Peri Noori, Margarita Ivanchenko, Laura Piñero Páez, Laura Gonzalez, Constantin Habimana Mugabo, Anette Johnsson, Henrik Ryberg, Åsa Hallgren, Christian Pou, Yang Chen, Jaromír Mikeš, Anna James, Per Dahlqvist, Jeanette Wahlberg, Anders Hagelin, Mats Holmberg, Marie Degerblad, Magnus Isaksson, Darragh Duffy, Olle Kämpe, Nils Landegren and Petter Brodin

Human organoids with an autologous tissue-resident immune compartment pp. 165-173

Timothy Recaldin, Linda Steinacher, Bruno Gjeta, Marius F. Harter, Lukas Adam, Kristina Kromer, Marisa Pimentel Mendes, Marina Bellavista, Mikhail Nikolaev, Giacomo Lazzaroni, Rok Krese, Umut Kilik, Doris Popovic, Bilgenaz Stoll, Régine Gerard, Michael Bscheider, Marc Bickle, Lauriane Cabon, J. Gray Camp and Nikolche Gjorevski

Spatially clustered type I interferon responses at injury borderzones pp. 174-181

V. K. Ninh, D. M. Calcagno, J. D. Yu, B. Zhang, N. Taghdiri, R. Sehgal, J. M. Mesfin, C. J. Chen, K. Kalhor, A. Toomu, J. M. Duran, E. Adler, J. Hu, K. Zhang, K. L. Christman, Z. Fu, B. Bintu and K. R. King

PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity pp. 182-188

Wei Wei, Xuchao Lyu, Andrew L. Markhard, Sipei Fu, Rachel E. Mardjuki, Peter E. Cavanagh, Xianfeng Zeng, Jakub Rajniak, Nannan Lu, Shuke Xiao, Meng Zhao, Maria Dolores Moya-Garzon, Steven D. Truong, Jonathan Chiu‐Chun Chou, Lianna W. Wat, Saranya Chidambaranathan-Reghupaty, Laetitia Coassolo, Duo Xu, Fangfang Shen, Wentao Huang, Cuauhtemoc B. Ramirez, Cholsoon Jang, Lingyin Li, Katrin J. Svensson, Michael A. Fischbach and Jonathan Z. Long

Remodelling of the translatome controls diet and its impact on tumorigenesis pp. 189-197

Haojun Yang, Vincenzo Andrea Zingaro, James Lincoff, Harrison Tom, Satoshi Oikawa, Juan A. Oses-Prieto, Quinn Edmondson, Ian Seiple, Hardik Shah, Shingo Kajimura, Alma L. Burlingame, Michael Grabe and Davide Ruggero

Mechanisms that clear mutations drive field cancerization in mammary tissue pp. 198-206

Marta Ciwinska, Hendrik A. Messal, Hristina R. Hristova, Catrin Lutz, Laura Bornes, Theofilos Chalkiadakis, Rolf Harkes, Nathalia S. M. Langedijk, Stefan J. Hutten, Renée X. Menezes, Jos Jonkers, Stefan Prekovic, Benjamin D. Simons, Colinda L. G. J. Scheele and Jacco van Rheenen

Neuronal substance P drives metastasis through an extracellular RNA–TLR7 axis pp. 207-215

Veena Padmanaban, Isabel Keller, Ethan S. Seltzer, Benjamin N. Ostendorf, Zachary Kerner and Sohail F. Tavazoie

Structural basis for transthiolation intermediates in the ubiquitin pathway pp. 216-223

Tomasz Kochańczyk, Zachary S. Hann, Michaelyn C. Lux, Avelyn Mae V. Delos Reyes, Cheng Ji, Derek S. Tan and Christopher D. Lima

Molecular architecture of coronavirus double-membrane vesicle pore complex pp. 224-231

Yixin Huang, Tongyun Wang, Lijie Zhong, Wenxin Zhang, Yu Zhang, Xiulian Yu, Shuofeng Yuan and Tao Ni

The ribosome lowers the entropic penalty of protein folding pp. 232-239

Julian O. Streit, Ivana V. Bukvin, Sammy H. S. Chan, Shahzad Bashir, Lauren F. Woodburn, Tomasz Włodarski, Angelo Miguel Figueiredo, Gabija Jurkeviciute, Haneesh K. Sidhu, Charity R. Hornby, Christopher A. Waudby, Lisa D. Cabrita, Anaïs M. E. Cassaignau and John Christodoulou

Massive Attack’s science-led drive to lower music’s carbon footprint pp. 241-243

Esme Hedley

Why I love drilling in the mountains early in the morning pp. 246-246

Esme Hedley