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2007, volume 448, articles 7157

Air force had early warning of pulsars pp. 974-975

Geoff Brumfiel

Market takes a gamble on carbon futures pp. 975-975

Emma Marris

Cheaper approaches to flu divide researchers pp. 976-977

Declan Butler

Flying insects threaten to deafen Japan pp. 977-977

David Cyranoski

No confidence vote for agency head pp. 979-979

Emma Marris

Spring theory pp. 984-986

Brendan Maher

Dreams of the new space race pp. 988-991

David Chandler

Libya should stop denying scientific evidence on HIV pp. 992-992

Vittorio Colizzi, Tulio de Oliveira and Richard J. Roberts

Fires and climate linked in nineteenth century pp. 992-992

Stefan Brönnimann

Climate: Sawyer predicted rate of warming in 1972 pp. 992-992

Neville Nicholls

Cashing in palm oil for conservation pp. 993-994

Lian Pin Koh and David S. Wilcove

An illusionary rival pp. 995-996

Siân Ede

Two camps at cross-purposes pp. 996-997

Paul D. Blanc

Celebrating four centuries of astronomy pp. 997-997

René Racine

Linguistic gem or just another pidgin? pp. 998-998

Neil Smith

Females can also be from Mars pp. 999-1000

Nirao M. Shah and S. Marc Breedlove

A black hole full of answers pp. 1000-1001

Jan Zaanen

Damage control pp. 1001-1002

Claus M. Azzalin and Joachim Lingner

The first movement pp. 1003-1003

Jeff Cuzzi

Duality in the genetic code pp. 1004-1005

John F. Atkins and Pavel V. Baranov

Oxygen's rise reduced pp. 1005-1006

Timothy W. Lyons

Polymer crystals downsized pp. 1006-1007

Stephen Z. D. Cheng

A functional circuit underlying male sexual behaviour in the female mouse brain pp. 1009-1014

Tali Kimchi, Jennings Xu and Catherine Dulac

IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro pp. 1015-1021

Sean C. Bendall, Morag H. Stewart, Pablo Menendez, Dustin George, Kausalia Vijayaragavan, Tamra Werbowetski-Ogilvie, Veronica Ramos-Mejia, Anne Rouleau, Jiabi Yang, Marc Bossé, Gilles Lajoie and Mickie Bhatia

Rapid planetesimal formation in turbulent circumstellar disks pp. 1022-1025

Anders Johansen, Jeffrey S. Oishi, Mordecai-Mark Mac Low, Hubert Klahr, Thomas Henning and Andrew Youdin

The development of a protoplanetary disk from its natal envelope pp. 1026-1028

Dan M. Watson, C. J. Bohac, C. Hull, William J. Forrest, E. Furlan, J. Najita, Nuria Calvet, Paola d’Alessio, Lee Hartmann, B. Sargent, Joel D. Green, Kyoung Hee Kim and J. R. Houck

Direct observation of second-order atom tunnelling pp. 1029-1032

S. Fölling, S. Trotzky, P. Cheinet, M. Feld, R. Saers, A. Widera, T. Müller and I. Bloch

Increased subaerial volcanism and the rise of atmospheric oxygen 2.5 billion years ago pp. 1033-1036

Lee R. Kump and Mark E. Barley

Projected increase in continental runoff due to plant responses to increasing carbon dioxide pp. 1037-1041

Richard A. Betts, Olivier Boucher, Matthew Collins, Peter M. Cox, Peter D. Falloon, Nicola Gedney, Deborah L. Hemming, Chris Huntingford, Chris D. Jones, David M. H. Sexton and Mark J. Webb

Dating the origin of the Orchidaceae from a fossil orchid with its pollinator pp. 1042-1045

Santiago R. Ramírez, Barbara Gravendeel, Rodrigo B. Singer, Charles R. Marshall and Naomi E. Pierce

Mobility promotes and jeopardizes biodiversity in rock–paper–scissors games pp. 1046-1049

Tobias Reichenbach, Mauro Mobilia and Erwin Frey

A sequence-based variation map of 8.27 million SNPs in inbred mouse strains pp. 1050-1053

Kelly A. Frazer, Eleazar Eskin, Hyun Min Kang, Molly A. Bogue, David A. Hinds, Erica J. Beilharz, Robert V. Gupta, Julie Montgomery, Matt M. Morenzoni, Geoffrey B. Nilsen, Charit L. Pethiyagoda, Laura L. Stuve, Frank M. Johnson, Mark J. Daly, Claire M. Wade and David R. Cox

The detection of carbonation by the Drosophila gustatory system pp. 1054-1057

Walter Fischler, Priscilla Kong, Sunanda Marella and Kristin Scott

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome pp. 1058-1062

Yoshiyuki Minegishi, Masako Saito, Shigeru Tsuchiya, Ikuya Tsuge, Hidetoshi Takada, Toshiro Hara, Nobuaki Kawamura, Tadashi Ariga, Srdjan Pasic, Oliver Stojkovic, Ayse Metin and Hajime Karasuyama

Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response pp. 1063-1067

Chiara Gorrini, Massimo Squatrito, Chiara Luise, Nelofer Syed, Daniele Perna, Landon Wark, Francesca Martinato, Domenico Sardella, Alessandro Verrecchia, Samantha Bennett, Stefano Confalonieri, Matteo Cesaroni, Francesco Marchesi, Milena Gasco, Eugenio Scanziani, Maria Capra, Sabine Mai, Paolo Nuciforo, Tim Crook, John Lough and Bruno Amati

Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1 pp. 1068-1071

Eros Lazzerini Denchi and Titia de Lange

Crystal structure of the MgtE Mg2+ transporter pp. 1072-1075

Motoyuki Hattori, Yoshiki Tanaka, Shuya Fukai, Ryuichiro Ishitani and Osamu Nureki

Erratum: RNA-templated DNA repair pp. 1076-1076

Francesca Storici, Katarzyna Bebenek, Thomas A. Kunkel, Dmitry A. Gordenin and Michael A. Resnick

Erratum: A positive-feedback-based bistable ‘memory module’ that governs a cell fate decision pp. 1076-1076

Wen Xiong and James E. Ferrell

Erratum: Structure of the E. coli signal recognition particle bound to a translating ribosome pp. 1076-1076

Christiane Schaffitzel, Miro Oswald, Imre Berger, Takashi Ishikawa, Jan Pieter Abrahams, Henk K. Koerten, Roman I. Koning and Nenad Ban

Prospects pp. 1077-1077

Gene Russo

A new note for Nat pp. 1080-1080

Gareth Owens

2007, volume 448, articles 7156

Is CdCr2S4 a multiferroic relaxor? pp. E4-E5

Gustau Catalan and James F. Scott

Is CdCr2S4 a multiferroic relaxor? (reply) pp. E5-E6

Joachim Hemberger, Peter Lunkenheimer, Robert Fichtl, Hans-Albrecht Krug von Nidda, Vladimir Tsurkan and Alois Loidl

Oldest gorilla ages our joint ancestor pp. 844-844

Rex Dalton

Ocean circulation noisy, not stalling pp. 844-845

Quirin Schiermeier

Fleece myth hints at golden age for Georgia pp. 846-846

Emiliano Feresin

Journal presents a mathematical conundrum pp. 846-847

Jenny Hogan

Is baby DVD research Mickey Mouse science? pp. 848-849

Daniel Cressey

More biologists but tenure stays static pp. 848-848

Erika Check

Let down by the statistics pp. 849-849

Claire Ainsworth

Hope for axed cancer-prevention trial pp. 850-850

Meredith Wadman

Market watch pp. 853-853

Colin Macilwain

Hitting the on switch pp. 855-858

Erika Check

Making room pp. 860-863

Emma Marris

Scientists should unite against threat from religion pp. 864-864

Sam Harris

Religion: Islamic science fading before colonialism pp. 864-864

Todd P. Silverstein

Berlin shows how natural history can pull the crowds pp. 864-864

Nizar Ibrahim

Puns can be baffling, so keep headlines simple pp. 864-865

Jeff Craig

Puns: wimp or macho, not a particle of offence is meant pp. 865-865

Milan Hopkins

Regions unite to challenge inequalities in Brazil pp. 865-865

Luiz A. B. Castro and Allan Kardec Barros

Summing up The Simpsons pp. 865-865

J. Ewart H. Shaw

Drop 'higher' and 'lower' to raise descriptive standards pp. 865-865

Michael Mogie

Four ways to take the policy plunge pp. 867-867

Andrew A. Rosenberg

Linnaeus lives on pp. 868-869

Pamela S. Soltis

Mankind's strange love of superweapons pp. 868-868

Gregg Herken

The theatre of quantum physics pp. 869-870

Finn Aaserud

Medical history without frontiers pp. 870-870

Yasmin Khan

Obsessed with grooming pp. 871-872

Steven E. Hyman

Wave goodbye pp. 872-873

Luis A. Orozco

Age, health and wealth pp. 875-876

Frances Cairncross

Stirring stuff pp. 876-877

David J. Pine

Structure in mutualistic networks pp. 877-879

Susanne S. Renner

Embedded shells decalcified pp. 879-880

Catherine Picart and Dennis E. Discher

Old diamonds and the upper crust pp. 880-881

Ian S. Williams

Daniel Koshland (1920–2007) pp. 882-882

Bruce Alberts

Integrating molecular and network biology to decode endocytosis pp. 883-888

Eva M. Schmid and Harvey T. McMahon

Progressive field-state collapse and quantum non-demolition photon counting pp. 889-893

Christine Guerlin, Julien Bernu, Samuel Deléglise, Clément Sayrin, Sébastien Gleyzes, Stefan Kuhr, Michel Brune, Jean-Michel Raimond and Serge Haroche

Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice pp. 894-900

Jeffrey M. Welch, Jing Lu, Ramona M. Rodriguiz, Nicholas C. Trotta, Joao Peca, Jin-Dong Ding, Catia Feliciano, Meng Chen, J. Paige Adams, Jianhong Luo, Serena M. Dudek, Richard J. Weinberg, Nicole Calakos, William C. Wetsel and Guoping Feng

Gap junction adhesion is necessary for radial migration in the neocortex pp. 901-907

Laura A. B. Elias, Doris D. Wang and Arnold R. Kriegstein

No extreme bipolar glaciation during the main Eocene calcite compensation shift pp. 908-911

Kirsty M. Edgar, Paul A. Wilson, Philip F. Sexton and Yusuke Suganuma

Northern Hemisphere forcing of climatic cycles in Antarctica over the past 360,000 years pp. 912-916

Kenji Kawamura, Frédéric Parrenin, Lorraine Lisiecki, Ryu Uemura, Françoise Vimeux, Jeffrey P. Severinghaus, Manuel A. Hutterli, Takakiyo Nakazawa, Shuji Aoki, Jean Jouzel, Maureen E. Raymo, Koji Matsumoto, Hisakazu Nakata, Hideaki Motoyama, Shuji Fujita, Kumiko Goto-Azuma, Yoshiyuki Fujii and Okitsugu Watanabe

Hadean diamonds in zircon from Jack Hills, Western Australia pp. 917-920

Martina Menneken, Alexander A. Nemchin, Thorsten Geisler, Robert T. Pidgeon and Simon A. Wilde

A new species of great ape from the late Miocene epoch in Ethiopia pp. 921-924

Gen Suwa, Reiko T. Kono, Shigehiro Katoh, Berhane Asfaw and Yonas Beyene

Non-random coextinctions in phylogenetically structured mutualistic networks pp. 925-928

Enrico L. Rezende, Jessica E. Lavabre, Paulo R. Guimarães, Pedro Jordano and Jordi Bascompte

Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells pp. 929-933

Hiroyuki Tezuka, Yukiko Abe, Makoto Iwata, Hajime Takeuchi, Hiromichi Ishikawa, Masayuki Matsushita, Tetsuo Shiohara, Shizuo Akira and Toshiaki Ohteki

An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus pp. 934-937

Matthieu Giraud, Richard Taubert, Claire Vandiedonck, Xiayi Ke, Matthieu Lévi-Strauss, Franco Pagani, Francisco E. Baralle, Bruno Eymard, Christine Tranchant, Philippe Gajdos, Angela Vincent, Nick Willcox, David Beeson, Bruno Kyewski and Henri-Jean Garchon

A central integrator of transcription networks in plant stress and energy signalling pp. 938-942

Elena Baena-González, Filip Rolland, Johan M. Thevelein and Jen Sheen

p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a pp. 943-946

Paul Krimpenfort, Annemieke IJpenberg, Ji-Ying Song, Martin van der Valk, Martijn Nawijn, John Zevenhoven and Anton Berns

The effects of molecular noise and size control on variability in the budding yeast cell cycle pp. 947-951

Stefano Di Talia, Jan M. Skotheim, James M. Bean, Eric D. Siggia and Frederick R. Cross

Antidepressant binding site in a bacterial homologue of neurotransmitter transporters pp. 952-956

Satinder K. Singh, Atsuko Yamashita and Eric Gouaux

Tissue issues pp. 959-960

Nathan Blow

The pharmaceutical industry has had big job losses of late pp. 965-965

Gene Russo

Formic gender disorder pp. 968-968

Barrington J. Bayley

2007, volume 448, articles 7155

Not so secure after all pp. 732-733

Daniel Cressey

Achievement index climbs the ranks pp. 737-737

Philip Ball

Trouble in paradise pp. 738-738

David Cyranoski

Transparency urged over research payments pp. 738-738

Erika Check

Space exploration: Secrets of the martian soil pp. 742-744

Corinna Wu

Space invaders pp. 746-748

Katharine Sanderson

Scientific bodies must take own action on emissions pp. 749-749

Andrew Biggin

Bush has not obstructed environmental protection pp. 749-749

Granta Nakayama

Chemical reaction to the many-worlds hypothesis pp. 749-749

Pedro Cintas

International research may leave women adrift pp. 749-749

Asha Gopinathan

The art of persuasion pp. 751-752

Steven Shapin

Material metaphors pp. 752-753

Robert N. Proctor

Left to digest pp. 753-753

Paolo Mazzarello and Maurizio Harari

Enzymes line up for assembly pp. 755-756

Nicholas M. Llewellyn and Jonathan B. Spencer

Talc at fault pp. 756-757

Christopher Wibberley

Designer enzymes pp. 757-758

Michael P. Robertson and William G. Scott

Metal turned to glass pp. 758-759

Gilles Tarjus

Pro-survival effects of PINK1 pp. 759-760

Asa Abeliovich

Photons from a hotter hell pp. 760-761

Trevor Weekes

Models of transition pp. 762-763

JoAnne Stubbe

Coastal catastrophe in Phoenicia pp. 763-763

Tim Lincoln

Anne McLaren (1927–2007) pp. 764-765

Azim Surani and Jim Smith

Donald Michie (1923–2007) pp. 765-765

Margaret Boden

The common biology of cancer and ageing pp. 767-774

Toren Finkel, Manuel Serrano and Maria A. Blasco

Structure-based activity prediction for an enzyme of unknown function pp. 775-779

Johannes C. Hermann, Ricardo Marti-Arbona, Alexander A. Fedorov, Elena Fedorov, Steven C. Almo, Brian K. Shoichet and Frank M. Raushel

A turbulent wake as a tracer of 30,000 years of Mira’s mass loss history pp. 780-783

D. Christopher Martin, Mark Seibert, James D. Neill, David Schiminovich, Karl Forster, R. Michael Rich, Barry Y. Welsh, Barry F. Madore, Jonathan M. Wheatley, Patrick Morrissey and Tom A. Barlow

Generation of optical ‘Schrödinger cats’ from photon number states pp. 784-786

Alexei Ourjoumtsev, Hyunseok Jeong, Rosa Tualle-Brouri and Philippe Grangier

Vitrification of a monatomic metallic liquid pp. 787-790

M. H. Bhat, V. Molinero, E. Soignard, V. C. Solomon, S. Sastry, J. L. Yarger and C. A. Angell

Indirect radiative forcing of climate change through ozone effects on the land-carbon sink pp. 791-794

S. Sitch, P. M. Cox, W. J. Collins and C. Huntingford

Talc-bearing serpentinite and the creeping section of the San Andreas fault pp. 795-797

Diane E. Moore and Michael J. Rymer

Female mate-choice drives the evolution of male-biased dispersal in a social mammal pp. 798-801

O. P. Höner, B. Wachter, M. L. East, W. J. Streich, K. Wilhelm, T. Burke and H. Hofer

Correlation between neural spike trains increases with firing rate pp. 802-806

Jaime de la Rocha, Brent Doiron, Eric Shea-Brown, Krešimir Josić and Alex Reyes

LKB1 modulates lung cancer differentiation and metastasis pp. 807-810

Hongbin Ji, Matthew R. Ramsey, D. Neil Hayes, Cheng Fan, Kate McNamara, Piotr Kozlowski, Chad Torrice, Michael C. Wu, Takeshi Shimamura, Samanthi A. Perera, Mei-Chih Liang, Dongpo Cai, George N. Naumov, Lei Bao, Cristina M. Contreras, Danan Li, Liang Chen, Janakiraman Krishnamurthy, Jussi Koivunen, Lucian R. Chirieac, Robert F. Padera, Roderick T. Bronson, Neal I. Lindeman, David C. Christiani, Xihong Lin, Geoffrey I. Shapiro, Pasi A. Jänne, Bruce E. Johnson, Matthew Meyerson, David J. Kwiatkowski, Diego H. Castrillon, Nabeel Bardeesy, Norman E. Sharpless and Kwok-Kin Wong

Cdk1 is sufficient to drive the mammalian cell cycle pp. 811-815

David Santamaría, Cédric Barrière, Antonio Cerqueira, Sarah Hunt, Claudine Tardy, Kathryn Newton, Javier F. Cáceres, Pierre Dubus, Marcos Malumbres and Mariano Barbacid

Small self-RNA generated by RNase L amplifies antiviral innate immunity pp. 816-819

Krishnamurthy Malathi, Beihua Dong, Michael Gale and Robert H. Silverman

Break-induced replication and telomerase-independent telomere maintenance require Pol32 pp. 820-823

John R. Lydeard, Suvi Jain, Miyuki Yamaguchi and James E. Haber

A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines pp. 824-827

Pascal D. Fortin, Christopher T. Walsh and Nathan A. Magarvey

Selection and evolution of enzymes from a partially randomized non-catalytic scaffold pp. 828-831

Burckhard Seelig and Jack W. Szostak

US bill should give career opportunities in the physical sciences a boost pp. 833-833

Gene Russo

The seven-year itch pp. 834-835

Hannah Hoag

Succussion pp. 838-838

Steve Longworth

2007, volume 448, articles 7154

Crystallographic evidence for deviating C3b structure pp. E1-E2

Bert J. C. Janssen, Randy J. Read, Axel T. Brünger and Piet Gros

Crystallographic evidence for deviating C3b structure (Reply) pp. E2-E3

A. Abdul Ajees, Krishnasamy Gunasekaran, Sthanam V. L. Narayana and H. M. Krishna Murthy

A genetic switch for gender bending pp. 630-631

Kerri Smith

Chemists synthesize a natural-born killer pp. 630-630

Katharine Sanderson

US genetics bill blocked again pp. 631-631

Meredith Wadman

Strike threat over jailed primatologist pp. 634-634

Erika Check and Thomas Hayden

Market watch pp. 637-637

Colin Macilwain

Tails of the unexpected pp. 638-641

Claire Ainsworth

Steaming ahead pp. 642-643

K. S. Jayaraman

Public engagement means listening as well as talking pp. 644-644

Fern Wickson

Public engagement: both sides need to be realistic pp. 644-644

Richard Wilson

Physics Nobels should favour inventions pp. 644-644

Christoph Bartneck and Matthias Rauterberg

Traditional remedies put animal species at risk pp. 644-644

Margaret B. Murphy

New uses for old drugs pp. 645-646

Curtis R. Chong and David J. Sullivan

Social science goes virtual pp. 647-648

Philip Ball

In the eye of the storm pp. 648-648

James Elsner

Remarkable but not so unusual pp. 649-650

Judith P. Zinsser

Palaeontology meets Hanna-Barbera pp. 650-650

Colin Martin

Double vision pp. 651-652

Andrea Cavalleri

Timing is everything pp. 652-653

Phillip Larimer and Ben W. Strowbridge

Ions illuminated pp. 654-655

Christopher J. Chang

The lost continents pp. 655-656

Albrecht W. Hofmann

Colour discrimination pp. 656-656

Richard Webb

World of insects pp. 657-658

Nigel E. Stork

A down-to-Earth approach pp. 658-659

John R. Helliwell and Naomi E. Chayen

Jasmonate perception machines pp. 659-660

Edward E. Farmer

JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling pp. 661-665

Bryan Thines, Leron Katsir, Maeli Melotto, Yajie Niu, Ajin Mandaokar, Guanghui Liu, Kinya Nomura, Sheng Yang He, Gregg A. Howe and John Browse

The JAZ family of repressors is the missing link in jasmonate signalling pp. 666-671

A. Chini, S. Fonseca, G. Fernández, B. Adie, J. M. Chico, O. Lorenzo, G. García-Casado, I. López-Vidriero, F. M. Lozano, M. R. Ponce, J. L. Micol and R. Solano

Strong dipolar effects in a quantum ferrofluid pp. 672-675

Thierry Lahaye, Tobias Koch, Bernd Fröhlich, Marco Fattori, Jonas Metz, Axel Griesmaier, Stefano Giovanazzi and Tilman Pfau

Femtosecond time-delay X-ray holography pp. 676-679

Henry N. Chapman, Stefan P. Hau-Riege, Michael J. Bogan, Saša Bajt, Anton Barty, Sébastien Boutet, Stefano Marchesini, Matthias Frank, Bruce W. Woods, W. Henry Benner, Richard A. London, Urs Rohner, Abraham Szöke, Eberhard Spiller, Thomas Möller, Christoph Bostedt, David A. Shapiro, Marion Kuhlmann, Rolf Treusch, Elke Plönjes, Florian Burmeister, Magnus Bergh, Carl Caleman, Gösta Huldt, M. Marvin Seibert and Janos Hajdu

Intense mixing of lower thermocline water on the crest of the Mid-Atlantic Ridge pp. 680-683

Louis C. St Laurent and Andreas M. Thurnherr

The return of subducted continental crust in Samoan lavas pp. 684-687

Matthew G. Jackson, Stanley R. Hart, Anthony A. P. Koppers, Hubert Staudigel, Jasper Konter, Jerzy Blusztajn, Mark Kurz and Jamie A. Russell

Implications of new early Homo fossils from Ileret, east of Lake Turkana, Kenya pp. 688-691

F. Spoor, M. G. Leakey, P. N. Gathogo, F. H. Brown, S. C. Antón, I. McDougall, C. Kiarie, F. K. Manthi and L. N. Leakey

Low beta diversity of herbivorous insects in tropical forests pp. 692-695

Vojtech Novotny, Scott E. Miller, Jiri Hulcr, Richard A. I. Drew, Yves Basset, Milan Janda, Gregory P. Setliff, Karolyn Darrow, Alan J. A. Stewart, John Auga, Brus Isua, Kenneth Molem, Markus Manumbor, Elvis Tamtiai, Martin Mogia and George D. Weiblen

Host specificity of Lepidoptera in tropical and temperate forests pp. 696-699

L. A. Dyer, M. S. Singer, J. T. Lill, J. O. Stireman, G. L. Gentry, R. J. Marquis, R. E. Ricklefs, H. F. Greeney, D. L. Wagner, H. C. Morais, I. R. Diniz, T. A. Kursar and P. D. Coley

A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord pp. 700-703

Yan-Gang Sun and Zhou-Feng Chen

Global changes to the ubiquitin system in Huntington's disease pp. 704-708

Eric J. Bennett, Thomas A. Shaler, Ben Woodman, Kwon-Yul Ryu, Tatiana S. Zaitseva, Christopher H. Becker, Gillian P. Bates, Howard Schulman and Ron R. Kopito

Hebbian STDP in mushroom bodies facilitates the synchronous flow of olfactory information in locusts pp. 709-713

Stijn Cassenaer and Gilles Laurent

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA pp. 714-717

Steen K. T. Ooi, Chen Qiu, Emily Bernstein, Keqin Li, Da Jia, Zhe Yang, Hediye Erdjument-Bromage, Paul Tempst, Shau-Ping Lin, C. David Allis, Xiaodong Cheng and Timothy H. Bestor

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression pp. 718-722

Fei Lan, Robert E. Collins, Rossella De Cegli, Roman Alpatov, John R. Horton, Xiaobing Shi, Or Gozani, Xiaodong Cheng and Yang Shi

Prospects pp. 723-723

Gene Russo

What I did on my holidays pp. 726-726

Ian Stewart

2007, volume 448, articles 7153

The mouse map gets a lot more signposts pp. 516-517

Ewen Callaway

China's green accounting system on shaky ground pp. 518-519

Jane Qiu

New life for nuclear warheads pp. 520-521

Geoff Brumfiel

Russia at forefront of Arctic land-grab pp. 520-520

Daniel Cressey

Implant boosts activity in injured brain pp. 522-522

Michael Hopkin

Flatworms' starring role in stem-cell research pp. 522-522

Heidi Ledford

Making room for dissent pp. 524-524

David Goldston

The other greenhouse effect pp. 526-528

Ned Stafford

Trial and error pp. 530-532

Heidi Ledford

Profit or perish even worse than publish or perish pp. 533-533

Edward Kiegle

Interdisciplinary research could pull cash into science pp. 533-533

John R. Helliwell

The 'hundred surnames' of China run into thousands pp. 533-533

Dafeng Hui

University speaks up in dispute over cancer centre pp. 533-533

Virgil Renzulli

Climate information helps homeowners make choices pp. 533-533

David Purcell

Social climbers pp. 535-536

Asif A. Ghazanfar

The atomic peacemaker pp. 536-537

Yaron Ezrahi

Nervous systems made simple pp. 537-537

Eve Marder

Consulting nature's pattern-book pp. 538-538

Martin Kemp

An awakening pp. 539-540

Michael N. Shadlen and Roozbeh Kiani

Aerosols heat up pp. 541-542

Peter Pilewskie

The inside story pp. 542-544

Laurie E. Comstock

Champing at the bit pp. 544-545

Russell P. Cowburn

Broken genes in solid tumours pp. 545-546

Matthew Meyerson

Managed mess pp. 546-547

Zachary Fisk

An infernal triangle pp. 547-548

Alberto Mantovani

The epigenomic era opens pp. 548-549

Stephen B. Baylin and Kornel E. Schuebel

Climate change and the ecologist pp. 550-552

Wilfried Thuiller

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells pp. 553-560

Tarjei S. Mikkelsen, Manching Ku, David B. Jaffe, Biju Issac, Erez Lieberman, Georgia Giannoukos, Pablo Alvarez, William Brockman, Tae-Kyung Kim, Richard P. Koche, William Lee, Eric Mendenhall, Aisling O’Donovan, Aviva Presser, Carsten Russ, Xiaohui Xie, Alexander Meissner, Marius Wernig, Rudolf Jaenisch, Chad Nusbaum, Eric S. Lander and Bradley E. Bernstein

Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer pp. 561-566

Manabu Soda, Young Lim Choi, Munehiro Enomoto, Shuji Takada, Yoshihiro Yamashita, Shunpei Ishikawa, Shin-ichiro Fujiwara, Hideki Watanabe, Kentaro Kurashina, Hisashi Hatanaka, Masashi Bando, Shoji Ohno, Yuichi Ishikawa, Hiroyuki Aburatani, Toshiro Niki, Yasunori Sohara, Yukihiko Sugiyama and Hiroyuki Mano

A ferromagnet in a continuously tunable random field pp. 567-570

D. M. Silevitch, D. Bitko, J. Brooke, S. Ghosh, G. Aeppli and T. F. Rosenbaum

Electronic spin transport and spin precession in single graphene layers at room temperature pp. 571-574

Nikolaos Tombros, Csaba Jozsa, Mihaita Popinciuc, Harry T. Jonkman and Bart J. van Wees

Warming trends in Asia amplified by brown cloud solar absorption pp. 575-578

Veerabhadran Ramanathan, Muvva V. Ramana, Gregory Roberts, Dohyeong Kim, Craig Corrigan, Chul Chung and David Winker

Non-volcanic tremor driven by large transient shear stresses pp. 579-582

Justin L. Rubinstein, John E. Vidale, Joan Gomberg, Paul Bodin, Kenneth C. Creager and Stephen D. Malone

Jaws and teeth of the earliest bony fishes pp. 583-586

Hector Botella, Henning Blom, Markus Dorka, Per Erik Ahlberg and Philippe Janvier

Morphological evolution through multiple cis-regulatory mutations at a single gene pp. 587-590

Alistair P. McGregor, Virginie Orgogozo, Isabelle Delon, Jennifer Zanet, Dayalan G. Srinivasan, François Payre and David L. Stern

A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene pp. 591-594

Hakon Hakonarson, Struan F. A. Grant, Jonathan P. Bradfield, Luc Marchand, Cecilia E. Kim, Joseph T. Glessner, Rosemarie Grabs, Tracy Casalunovo, Shayne P. Taback, Edward C. Frackelton, Margaret L. Lawson, Luke J. Robinson, Robert Skraban, Yang Lu, Rosetta M. Chiavacci, Charles A. Stanley, Susan E. Kirsch, Eric F. Rappaport, Jordan S. Orange, Dimitri S. Monos, Marcella Devoto, Hui-Qi Qu and Constantin Polychronakos

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer pp. 595-599

Scott A. Tomlins, Bharathi Laxman, Saravana M. Dhanasekaran, Beth E. Helgeson, Xuhong Cao, David S. Morris, Anjana Menon, Xiaojun Jing, Qi Cao, Bo Han, Jindan Yu, Lei Wang, James E. Montie, Mark A. Rubin, Kenneth J. Pienta, Diane Roulston, Rajal B. Shah, Sooryanarayana Varambally, Rohit Mehra and Arul M. Chinnaiyan

Behavioural improvements with thalamic stimulation after severe traumatic brain injury pp. 600-603

N. D. Schiff, J. T. Giacino, K. Kalmar, J. D. Victor, K. Baker, M. Gerber, B. Fritz, B. Eisenberg, J. O’Connor, E. J. Kobylarz, S. Farris, A. Machado, C. McCagg, F. Plum, J. J. Fins and A. R. Rezai

Common effector processing mediates cell-specific responses to stimuli pp. 604-608

Kathryn Miller-Jensen, Kevin A. Janes, Joan S. Brugge and Douglas A. Lauffenburger

Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis pp. 609-612

Hideo Ago, Yoshihide Kanaoka, Daisuke Irikura, Bing K. Lam, Tatsuro Shimamura, K. Frank Austen and Masashi Miyano

Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase pp. 613-616

Daniel Martinez Molina, Anders Wetterholm, Andreas Kohl, Andrew A. McCarthy, Damian Niegowski, Eva Ohlson, Tove Hammarberg, Said Eshaghi, Jesper Z. Haeggström and Pär Nordlund

Prospects pp. 617-617

Gene Russo

Climate of opportunity pp. 618-619

Amanda Haag

Junk pp. 622-622

Gord Sellar

2007, volume 448, articles 7152

Quake shuts world's largest nuclear plant pp. 392-393

David Cyranoski

Darfur lake is a 'mirage' pp. 394-394

Declan Butler

California campuses resist industry restrictions pp. 394-395

Erika Check

Diamonds 'melted' inside an onion pp. 396-397

Philip Ball

Carbon sinks threatened by increasing ozone pp. 396-396

Michael Hopkin

Memory seen in the making pp. 397-397

Kerri Smith

Libyan ordeal ends: medics freed pp. 398-398

Declan Butler

Stem-cell researcher's move attracts funding pp. 398-398

Erika Check

Market watch pp. 401-401

Quirin Schiermeier

Mark of respect pp. 402-403

Michael Hopkin

Mmm... pi pp. 404-405

Michael Hopkin

The map man pp. 406-407

Meredith Wadman

Nobel laureates know what they're talking about pp. 408-408

Burton Richter

Nobel: politicians need the insights scientists can give pp. 408-408

Henry Kelly

How a naturalist found safe colours for soldiers pp. 408-408

James T. Costa

Post-publication review could aid skills and quality pp. 408-408

Todd A. Gibson

Driving a wedge into the Amazon pp. 409-410

William F. Laurance and Regina C. C. Luizão

A man of peace pp. 411-412

Malcolm Dando

Too much information pp. 412-413

Ann Blair

Introducing the extremophiles pp. 413-414

Sean Nee

Mind tricks pp. 414-414

Susana Martinez-Conde and Stephen L. Macknik

Uncharted route for antibiotics pp. 415-416

John P. Quinn

Narcissistic helpers pp. 416-417

Matthew T. Palmer and Casey T. Weaver

Photosynthesis in watercolours pp. 418-418

John Raven

Some assembly needed pp. 419-419

Ian Stewart

A ten per cent solution pp. 420-421

John Reinitz

Assault on the guardian pp. 421-422

Richard M. Ransohoff

Powered by symmetry pp. 422-423

Johannes Hecker Denschlag

Sensing the enemy within pp. 423-424

Hongbo Chi and Richard A. Flavell

Horst Tobias Witt (1922–2007) pp. 425-425

Wolfgang Junge and A. William Rutherford

Unravelling the pathogenesis of inflammatory bowel disease pp. 427-434

R. J. Xavier and D. K. Podolsky

A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum pp. 435-438

Hidde L. Ploegh

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer pp. 439-444

John D. Carpten, Andrew L. Faber, Candice Horn, Gregory P. Donoho, Stephen L. Briggs, Christiane M. Robbins, Galen Hostetter, Sophie Boguslawski, Tracy Y. Moses, Stephanie Savage, Mark Uhlik, Aimin Lin, Jian Du, Yue-Wei Qian, Douglas J. Zeckner, Greg Tucker-Kellogg, Jeffrey Touchman, Ketan Patel, Spyro Mousses, Michael Bittner, Richard Schevitz, Mei-Huei T. Lai, Kerry L. Blanchard and James E. Thomas

Non-transcriptional control of DNA replication by c-Myc pp. 445-451

David Dominguez-Sola, Carol Y. Ying, Carla Grandori, Luca Ruggiero, Brenden Chen, Muyang Li, Denise A. Galloway, Wei Gu, Jean Gautier and Riccardo Dalla-Favera

Controlled exchange interaction between pairs of neutral atoms in an optical lattice pp. 452-456

Marco Anderlini, Patricia J. Lee, Benjamin L. Brown, Jennifer Sebby-Strabley, William D. Phillips and J. V. Porto

Preparation and characterization of graphene oxide paper pp. 457-460

Dmitriy A. Dikin, Sasha Stankovich, Eric J. Zimney, Richard D. Piner, Geoffrey H. B. Dommett, Guennadi Evmenenko, SonBinh T. Nguyen and Rodney S. Ruoff

Detection of human influence on twentieth-century precipitation trends pp. 461-465

Xuebin Zhang, Francis W. Zwiers, Gabriele C. Hegerl, F. Hugo Lambert, Nathan P. Gillett, Susan Solomon, Peter A. Stott and Toru Nozawa

Variation in styles of rifting in the Gulf of California pp. 466-469

Daniel Lizarralde, Gary J. Axen, Hillary E. Brown, John M. Fletcher, Antonio González-Fernández, Alistair J. Harding, W. Steven Holbrook, Graham M. Kent, Pedro Paramo, Fiona Sutherland and Paul J. Umhoefer

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma pp. 470-473

Miriam F. Moffatt, Michael Kabesch, Liming Liang, Anna L. Dixon, David Strachan, Simon Heath, Martin Depner, Andrea von Berg, Albrecht Bufe, Ernst Rietschel, Andrea Heinzmann, Burkard Simma, Thomas Frischer, Saffron A. G. Willis-Owen, Kenny C. C. Wong, Thomas Illig, Christian Vogelberg, Stephan K. Weiland, Erika von Mutius, Gonçalo R. Abecasis, Martin Farrall, Ivo G. Gut, G. Mark Lathrop and William O. C. Cookson

Protective and therapeutic role for αB-crystallin in autoimmune demyelination pp. 474-479

Shalina S. Ousman, Beren H. Tomooka, Johannes M. van Noort, Eric F. Wawrousek, Kevin O’Conner, David A. Hafler, Raymond A. Sobel, William H. Robinson and Lawrence Steinman

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells pp. 480-483

Roza Nurieva, Xuexian O. Yang, Gustavo Martinez, Yongliang Zhang, Athanasia D. Panopoulos, Li Ma, Kimberly Schluns, Qiang Tian, Stephanie S. Watowich, Anton M. Jetten and Chen Dong

IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells pp. 484-487

Thomas Korn, Estelle Bettelli, Wenda Gao, Amit Awasthi, Anneli Jäger, Terry B. Strom, Mohamed Oukka and Vijay K. Kuchroo

Functional diversification of closely related ARF-GEFs in protein secretion and recycling pp. 488-492

Sandra Richter, Niko Geldner, Jarmo Schrader, Hanno Wolters, York-Dieter Stierhof, Gabino Rios, Csaba Koncz, David G. Robinson and Gerd Jürgens

An ARF-GEF acting at the Golgi and in selective endocytosis in polarized plant cells pp. 493-496

Ooi-kock Teh and Ian Moore

A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence pp. 497-500

Delphine Chinchilla, Cyril Zipfel, Silke Robatzek, Birgit Kemmerling, Thorsten Nürnberger, Jonathan D. G. Jones, Georg Felix and Thomas Boller

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response pp. 501-505

Akinori Takaoka, ZhiChao Wang, Myoung Kwon Choi, Hideyuki Yanai, Hideo Negishi, Tatsuma Ban, Yan Lu, Makoto Miyagishi, Tatsuhiko Kodama, Kenya Honda, Yusuke Ohba and Tadatsugu Taniguchi

Prospect pp. 507-507

Gene Russo

Gerd Kempermann, professor, Center for Regenerative Therapies, Dresden, Germany pp. 508-508

Virginia Gewin

Order of merit pp. 508-508

Christine Beveridge and Suzanne Morris

Isolation pp. 508-508

Moira Sheehan

And on gloomy Sunday pp. 510-510

Anthony S. Haines

2007, volume 448, articles 7151

High noon in Libya pp. 230-231

Declan Butler

Deep science strikes gold after latest site is named pp. 232-233

Geoff Brumfiel

Russia pins its hopes on 'nano' pp. 233-233

Quirin Schiermeier

US proposal for carbon cuts offers compromise pp. 234-234

Ewen Callaway

Get practical, urge climatologists pp. 234-235

Quirin Schiermeier

Seeing red pp. 236-236

David Cyranoski

Science watchdog baulks at merger pp. 236-236

Michael Hopkin

Welcome to the dark side pp. 240-245

Jenny Hogan

A constant problem pp. 245-248

Geoff Brumfiel

Friendly clarification from City of Brotherly Love pp. 250-251

Douglas J. Jerolmack

Race: talented minorities face a 'revolving door' pp. 250-250

Ben Barres

Race and tenure case was not handled fairly by MIT pp. 250-250

James Sherley

Foundation active in fight to cure Huntington's pp. 250-250

Nancy Wexler and Carl Johnson

Animal welfare is not just another bureaucratic hoop pp. 251-251

L. Bergmeier

Animal welfare: reporting details is good science pp. 251-251

C. M. Sherwin

UNAIDS rejects claims of exaggeration and bias pp. 251-251

Paul R. De Lay and Kevin M. De Cock

Chinese recorded classical nova two millennia ago pp. 251-251

Göran H. I. Johansson

The case of creation pp. 253-254

Kevin Padian

A lone voice in the greenhouse pp. 254-254

Robert J. Charlson

Ripples in relativity pp. 255-255

Clifford Will

Beijing bubbles pp. 256-256

Philip Ball

Walk the Planck pp. 257-257

Giovanni Amelino-Camelia

Europe cut adrift pp. 259-260

Philip Gibbard

The magic brew pp. 260-262

Janet Rossant

Interference in the matter pp. 262-263

Markus Kindermann

New order for thought disorders pp. 263-265

Lorna W. Role and David A. Talmage

Time for growth pp. 265-266

Ghislain Breton and Steve A. Kay

Caught in the traffic pp. 266-267

Aparna Lakkaraju and Enrique Rodriguez-Boulan

F. Anthony Dahlen (1942–2007) pp. 268-268

Guust Nolet

The Large Hadron Collider pp. 269-269

Alison Wright and Richard Webb

The making of the standard model pp. 271-273

Gerard 't Hooft

High-energy colliders and the rise of the standard model pp. 274-280

Terry Wyatt

How the LHC came to be pp. 281-284

Chris Llewellyn Smith

Building a behemoth pp. 285-289

Oliver Brüning and Paul Collier

Detector challenges at the LHC pp. 290-296

Steinar Stapnes

Beyond the standard model with the LHC pp. 297-301

John Ellis

The quest for the quark–gluon plasma pp. 302-309

Peter Braun-Munzinger and Johanna Stachel

The God particle et al pp. 310-312

Leon Lederman

Generation of germline-competent induced pluripotent stem cells pp. 313-317

Keisuke Okita, Tomoko Ichisaka and Shinya Yamanaka

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state pp. 318-324

Marius Wernig, Alexander Meissner, Ruth Foreman, Tobias Brambrink, Manching Ku, Konrad Hochedlinger, Bradley E. Bernstein and Rudolf Jaenisch

Conformational entropy in molecular recognition by proteins pp. 325-329

Kendra King Frederick, Michael S. Marlow, Kathleen G. Valentine and A. Joshua Wand

The sources of sodium escaping from Io revealed by spectral high definition imaging pp. 330-332

Michael Mendillo, Sophie Laurent, Jody Wilson, Jeffrey Baumgardner, Janusz Konrad and W. Clem Karl

Interference between two indistinguishable electrons from independent sources pp. 333-337

I. Neder, N. Ofek, Y. Chung, M. Heiblum, D. Mahalu and V. Umansky

A reversible wet/dry adhesive inspired by mussels and geckos pp. 338-341

Haeshin Lee, Bruce P. Lee and Phillip B. Messersmith

Catastrophic flooding origin of shelf valley systems in the English Channel pp. 342-345

Sanjeev Gupta, Jenny S. Collier, Andy Palmer-Felgate and Graeme Potter

The effect of ancient population bottlenecks on human phenotypic variation pp. 346-348

Andrea Manica, William Amos, François Balloux and Tsunehiko Hanihara

Positive darwinian selection at the imprinted MEDEA locus in plants pp. 349-352

Charles Spillane, Karl J. Schmid, Sylvia Laoueillé-Duprat, Stéphane Pien, Juan-Miguel Escobar-Restrepo, Célia Baroux, Valeria Gagliardini, Damian R. Page, Kenneth H. Wolfe and Ueli Grossniklaus

Variants conferring risk of atrial fibrillation on chromosome 4q25 pp. 353-357

Daniel F. Gudbjartsson, David O. Arnar, Anna Helgadottir, Solveig Gretarsdottir, Hilma Holm, Asgeir Sigurdsson, Adalbjorg Jonasdottir, Adam Baker, Gudmar Thorleifsson, Kristleifur Kristjansson, Arnar Palsson, Thorarinn Blondal, Patrick Sulem, Valgerdur M. Backman, Gudmundur A. Hardarson, Ebba Palsdottir, Agnar Helgason, Runa Sigurjonsdottir, Jon T. Sverrisson, Konstantinos Kostulas, Maggie C. Y. Ng, Larry Baum, Wing Yee So, Ka Sing Wong, Juliana C. N. Chan, Karen L. Furie, Steven M. Greenberg, Michelle Sale, Peter Kelly, Calum A. MacRae, Eric E. Smith, Jonathan Rosand, Jan Hillert, Ronald C. W. Ma, Patrick T. Ellinor, Gudmundur Thorgeirsson, Jeffrey R. Gulcher, Augustine Kong, Unnur Thorsteinsdottir and Kari Stefansson

Rhythmic growth explained by coincidence between internal and external cues pp. 358-361

Kazunari Nozue, Michael F. Covington, Paula D. Duek, Séverine Lorrain, Christian Fankhauser, Stacey L. Harmer and Julin N. Maloof

Two distinct modes of guidance signalling during collective migration of border cells pp. 362-365

Ambra Bianco, Minna Poukkula, Adam Cliffe, Juliette Mathieu, Carlos M. Luque, Tudor A. Fulga and Pernille Rørth

The Rab8 GTPase regulates apical protein localization in intestinal cells pp. 366-369

Takashi Sato, Sotaro Mushiake, Yukio Kato, Ken Sato, Miyuki Sato, Naoki Takeda, Keiichi Ozono, Kazunori Miki, Yoshiyuki Kubo, Akira Tsuji, Reiko Harada and Akihiro Harada

A bacterial E3 ubiquitin ligase targets a host protein kinase to disrupt plant immunity pp. 370-374

Tracy R. Rosebrock, Lirong Zeng, Jennifer J. Brady, Robert B. Abramovitch, Fangming Xiao and Gregory B. Martin

Delayed ageing through damage protection by the Arf/p53 pathway pp. 375-379

Ander Matheu, Antonio Maraver, Peter Klatt, Ignacio Flores, Isabel Garcia-Cao, Consuelo Borras, Juana M. Flores, Jose Viña, Maria A. Blasco and Manuel Serrano

Funding models can push the envelope, but at what cost? pp. 381-381

Gene Russo

Wise council pp. 382-383

Jill U. Adams

Robert Sterner, director, Division of Environmental Biology, National Science Foundation, Washington DC pp. 384-384

Virginia Gewin

Fountain of funding for youth pp. 384-384

Monya Baker

Vision pp. 384-384

Maria Ocampo-Hafalla

Modern mating pp. 386-386

John Zakour

2007, volume 448, articles 7150

HIV trial doomed by design, say critics pp. 110-111

Erika Check

Conserving life and livelihood pp. 111-111

Emma Marris

Austria's science institute gathers steam pp. 112-112

Carina Lenotti

Marks of distinction pp. 113-113

Alison Abbott

French universities to gain control pp. 113-113

Declan Butler

Fly library boosts gene tool supply pp. 115-115

Heidi Ledford

Activated eggs offer route to stem cells pp. 116-116

David Cyranoski

Technical advice pp. 119-119

David Goldston

Reading the book of death pp. 122-125

Nick Lane

A culture in the balance pp. 126-128

Jane Qiu

Authors' financial interests should be made known to manuscript reviewers pp. 129-129

Inmaculada de Melo-Martín and Kristen Intemann

Space-time safe — at least until the LHC switches on pp. 129-129

Thomas Dent

Mentors could support a student reviewer database pp. 129-129

Angelo P. Pernetta

Mentors: public lists would help students choose pp. 129-130

Ben Barres

How incompatibilities may have led to eukaryotic cell pp. 130-130

Yaacov Davidov and Edouard Jurkevitch

Text mining: powering the database revolution pp. 130-130

Udo Hahn, Joachim Wermter, Rainer Blasczyk and Peter A. Horn

Beyond the troubled relationship pp. 131-133

Ziauddin Sardar

Imagine a better world pp. 135-136

Stuart L. Pimm

Degrees of change pp. 136-136

Stefan Rahmstorf

Culture costs lives pp. 137-137

Michael B. A. Oldstone

Linnaeus and taxonomy in Japan pp. 139-140

His Majesty The Emperor of Japan

Light in chains pp. 141-142

Niek F. van Hulst

Extending the message pp. 142-143

Patrick Cramer

Water on distant worlds pp. 143-145

Heather A. Knutson

Family roots pp. 145-146

Ragan M. Callaway and Bruce E. Mahall

Channelling cold reception pp. 147-148

Bernd Nilius and Thomas Voets

Danger in the diet pp. 148-148

Tim Lincoln

Pierre-Gilles de Gennes (1932–2007) pp. 149-149

Françoise Brochard-Wyart

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila pp. 151-156

Georg Dietzl, Doris Chen, Frank Schnorrer, Kuan-Chung Su, Yulia Barinova, Michaela Fellner, Beate Gasser, Kaolin Kinsey, Silvia Oppel, Susanne Scheiblauer, Africa Couto, Vincent Marra, Krystyna Keleman and Barry J. Dickson

Structural basis for transcription elongation by bacterial RNA polymerase pp. 157-162

Dmitry G. Vassylyev, Marina N. Vassylyeva, Anna Perederina, Tahir H. Tahirov and Irina Artsimovitch

Structural basis for substrate loading in bacterial RNA polymerase pp. 163-168

Dmitry G. Vassylyev, Marina N. Vassylyeva, Jinwei Zhang, Murali Palangat, Irina Artsimovitch and Robert Landick

Water vapour in the atmosphere of a transiting extrasolar planet pp. 169-171

Giovanna Tinetti, Alfred Vidal-Madjar, Mao-Chang Liang, Jean-Philippe Beaulieu, Yuk Yung, Sean Carey, Robert J. Barber, Jonathan Tennyson, Ignasi Ribas, Nicole Allard, Gilda E. Ballester, David K. Sing and Franck Selsis

Compositional homogeneity in the fragmented comet 73P/Schwassmann–Wachmann 3 pp. 172-175

N. Dello Russo, R. J. Vervack, H. A. Weaver, N. Biver, D. Bockelée-Morvan, J. Crovisier and C. M. Lisse

High-resolution spectroscopy of two-dimensional electron systems pp. 176-179

O. E. Dial, R. C. Ashoori, L. N. Pfeiffer and K. W. West

Reversal of the net dinitrogen gas flux in coastal marine sediments pp. 180-182

R. W. Fulweiler, S. W. Nixon, B. A. Buckley and S. L. Granger

Spreading rate dependence of gravity anomalies along oceanic transform faults pp. 183-187

Patricia M. Gregg, Jian Lin, Mark D. Behn and Laurent G. J. Montési

Biodiversity and ecosystem multifunctionality pp. 188-190

Andy Hector and Robert Bagchi

Derivation of pluripotent epiblast stem cells from mammalian embryos pp. 191-195

I. Gabrielle M. Brons, Lucy E. Smithers, Matthew W. B. Trotter, Peter Rugg-Gunn, Bowen Sun, Susana M. Chuva de Sousa Lopes, Sarah K. Howlett, Amanda Clarkson, Lars Ahrlund-Richter, Roger A. Pedersen and Ludovic Vallier

New cell lines from mouse epiblast share defining features with human embryonic stem cells pp. 196-199

Paul J. Tesar, Josh G. Chenoweth, Frances A. Brook, Timothy J. Davies, Edward P. Evans, David L. Mack, Richard L. Gardner and Ronald D. G. McKay

An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum pp. 200-203

Samuel J. Fountain, Katie Parkinson, Mark T. Young, Lishuang Cao, Christopher R. L. Thompson and R. Alan North

The menthol receptor TRPM8 is the principal detector of environmental cold pp. 204-208

Diana M. Bautista, Jan Siemens, Joshua M. Glazer, Pamela R. Tsuruda, Allan I. Basbaum, Cheryl L. Stucky, Sven-Eric Jordt and David Julius

An efflux transporter of silicon in rice pp. 209-212

Jian Feng Ma, Naoki Yamaji, Namiki Mitani, Kazunori Tamai, Saeko Konishi, Toru Fujiwara, Maki Katsuhara and Masahiro Yano

Antitumour drugs impede DNA uncoiling by topoisomerase I pp. 213-217

Daniel A. Koster, Komaraiah Palle, Elisa S. M. Bot, Mary-Ann Bjornsti and Nynke H. Dekker

Government-funded labs have their perks, and their challenges pp. 219-219

Gene Russo

Fighting Back pp. 220-221

Karen Fox

France Córdova, president, Purdue University, West Lafayette, Indiana pp. 222-222

Virginia Gewin

Engineering a place for women pp. 222-222

Roger Livesey

(Almost) in press pp. 222-222

Peter Jordan

A piratical sabbatical pp. 224-224

Ian Whates

2007, volume 448, articles 7149

The petaflop challenge pp. 6-7

Declan Butler

UK science reshuffled pp. 7-7

Katharine Sanderson

Cosmic-ray results auger well for future pp. 8-9

Jenny Hogan

No solar hiding place for greenhouse sceptics pp. 8-8

Quirin Schiermeier

The great gig in the South pp. 9-9

Katharine Sanderson

Faster still and faster pp. 10-11

Erika Check

War of words erupts over fossil dig pp. 12-12

Rex Dalton

See me here, see me there pp. 15-17

Mark Buchanan

Not so good when 75% of grant applications fail pp. 22-22

Philip Strange

Admission that intelligent design is a religious view pp. 22-22

H. A. Lessios

Terrorists are activists who renounce non-violence pp. 22-22

Sarah Reichard, Thomas M. Hinckley and H. D. Bradshaw

Activists: arson risks killing innocent people pp. 22-22

Mike Fainzilber

Activists: some walls are not meant to be breached pp. 22-22

Beverly E. Barton

Many lives in many worlds pp. 23-24

Max Tegmark

Surfing the multiverse pp. 25-26

Gary Wolfe

Art shadowing science pp. 26-26

Colin Martin

Science with flare pp. 27-28

Jan Stenflo

Falling victim to balance pp. 27-27

Timothy Miles

A greener education pp. 28-28

Peter Hopkinson

A constant surprise pp. 29-29

John Cowan

Ancient fingerprints in the clay pp. 31-32

David C. Catling

Designs for life pp. 32-33

Philip Ball

Entry granted pp. 33-34

Edouard M. Cantin and John J. Rossi

Mimicry on the edge pp. 35-36

Thomas N. Sherratt

How a T cell sees sugar pp. 36-37

D. Branch Moody

Hyperion the sponge pp. 37-37

Richard Webb

Transvascular delivery of small interfering RNA to the central nervous system pp. 39-43

Priti Kumar, Haoquan Wu, Jodi L. McBride, Kyeong-Eun Jung, Moon Hee Kim, Beverly L. Davidson, Sang Kyung Lee, Premlata Shankar and N. Manjunath

CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor pp. 44-49

Natalie A. Borg, Kwok S. Wun, Lars Kjer-Nielsen, Matthew C. J. Wilce, Daniel G. Pellicci, Ruide Koh, Gurdyal S. Besra, Mandvi Bharadwaj, Dale I. Godfrey, James McCluskey and Jamie Rossjohn

Hyperion's sponge-like appearance pp. 50-53

P. C. Thomas, J. W. Armstrong, S. W. Asmar, J. A. Burns, T. Denk, B. Giese, P. Helfenstein, L. Iess, T. V. Johnson, A. McEwen, L. Nicolaisen, C. Porco, N. Rappaport, J. Richardson, L. Somenzi, P. Tortora, E. P. Turtle and J. Veverka

Surface composition of Hyperion pp. 54-56

D. P. Cruikshank, J. B. Dalton, C. M. Dalle Ore, J. Bauer, K. Stephan, G. Filacchione, A. R. Hendrix, C. J. Hansen, A. Coradini, P. Cerroni, F. Tosi, F. Capaccioni, R. Jaumann, B. J. Buratti, R. N. Clark, R. H. Brown, R. M. Nelson, T. B. McCord, K. H. Baines, P. D. Nicholson, C. Sotin, A. W. Meyer, G. Bellucci, M. Combes, J.-P. Bibring, Y. Langevin, B. Sicardy, D. L. Matson, V. Formisano, P. Drossart and V. Mennella

Low-energy acoustic plasmons at metal surfaces pp. 57-59

Bogdan Diaconescu, Karsten Pohl, Luca Vattuone, Letizia Savio, Philip Hofmann, Vyacheslav M. Silkin, Jose M. Pitarke, Eugene V. Chulkov, Pedro M. Echenique, Daniel Farías and Mario Rocca

Early geochemical environment of Mars as determined from thermodynamics of phyllosilicates pp. 60-63

Vincent Chevrier, Francois Poulet and Jean-Pierre Bibring

Co-mimics have a mutualistic relationship despite unequal defences pp. 64-67

Hannah M. Rowland, Eira Ihalainen, Leena Lindström, Johanna Mappes and Michael P. Speed

Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J pp. 68-72

Clement Y. Chow, Yanling Zhang, James J. Dowling, Natsuko Jin, Maja Adamska, Kensuke Shiga, Kinga Szigeti, Michael E. Shy, Jun Li, Xuebao Zhang, James R. Lupski, Lois S. Weisman and Miriam H. Meisler

Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo pp. 73-77

Päivi Lindholm, Merja H. Voutilainen, Juha Laurén, Johan Peränen, Veli-Matti Leppänen, Jaan-Olle Andressoo, Maria Lindahl, Sanna Janhunen, Nisse Kalkkinen, Tõnis Timmusk, Raimo K. Tuominen and Mart Saarma

TRIC channels are essential for Ca2+ handling in intracellular stores pp. 78-82

Masayuki Yazawa, Christopher Ferrante, Jue Feng, Kazuhiro Mio, Toshihiko Ogura, Miao Zhang, Pei-Hui Lin, Zui Pan, Shinji Komazaki, Kazuhiro Kato, Miyuki Nishi, Xiaoli Zhao, Noah Weisleder, Chikara Sato, Jianjie Ma and Hiroshi Takeshima

Intronic microRNA precursors that bypass Drosha processing pp. 83-86

J. Graham Ruby, Calvin H. Jan and David P. Bartel

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity pp. 87-91

Stanley S. Ng, Kathryn L. Kavanagh, Michael A. McDonough, Danica Butler, Ewa S. Pilka, Benoit M. R. Lienard, James E. Bray, Pavel Savitsky, Opher Gileadi, Frank von Delft, Nathan R. Rose, John Offer, Johanna C. Scheinost, Tomasz Borowski, Michael Sundstrom, Christopher J. Schofield and Udo Oppermann

Structural snapshots along the reaction pathway of ferredoxin–thioredoxin reductase pp. 92-96

Shaodong Dai, Rosmarie Friemann, Dominique A. Glauser, Florence Bourquin, Wanda Manieri, Peter Schürmann and Hans Eklund

Prospects pp. 97-97

Gene Russo

Beyond the glass ceiling pp. 98-100

Kendall Powell

Closing the gender gap pp. 101-102

Magdalena Wutte

Olympic talent pp. 104-104

Richard A. Lovett