Selectively tuning γ-secretase

Peter St George-Hyslop and Gerold Schmitt-Ulms
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Peter St George-Hyslop: Peter St George-Hyslop is at the Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5S 3H2, Canada, and at the Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK. phs22@cam.ac.uk
Gerold Schmitt-Ulms: Gerold Schmitt-Ulms is at the Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5S 3H2, Canada.

Nature, 2010, vol. 467, issue 7311, 36-37

Abstract: Presenilin proteins have a major role in normal cellular processes, but some contribute to disease, for example through the formation of amyloid-β. The way in which these different roles are regulated is now becoming clearer.

Date: 2010
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DOI: 10.1038/467036a

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