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2015, volume 517, articles 7536

Gather data to reveal true extent of doping in sport pp. 529-529

Roger Pielke

A call for beautiful prose in papers pp. 531-531

Chris Woolston

Obama acts alone on climate pp. 535-536

Jeff Tollefson

Hunt for Philae hangs in the balance pp. 536-537

Elizabeth Gibney

Unconscious thought not so smart after all pp. 537-538

Alison Abbott

US ocean sciences told to steer a new course pp. 538-539

Alexandra Witze

US precision-medicine proposal sparks questions pp. 540-540

Sara Reardon

Neanderthals gain human neighbour pp. 541-541

Ewen Callaway

Cultural heritage: Save Libyan archaeology pp. 547-549

Savino di Lernia

Sociobiology: Altruists together pp. 550-551

Herbert Gintis

Books in brief pp. 551-551

Barbara Kiser

In praise of Holt as head of the AAAS pp. 553-553

Joseph Romm

Shale gas: Nuance in output predictions pp. 553-553

Steve Holditch, Dan Hill and Ruud Weijermars

Shale gas: Hardly a fallacy pp. 553-553

Scott W. Tinker and Svetlana Ikonnikova

United Nations highlights soil crisis pp. 553-553

Henry Lin and Rainer Horn

Donald Metcalf (1929–2014) pp. 554-554

Douglas Hilton

Emergency back-up for lung repair pp. 556-557

Emma L. Rawlins

Stellar clocks pp. 557-558

David Soderblom

Seeing the wood and the trees pp. 558-559

Anthony Bishopp and Malcolm J. Bennett

Relativity tested with a split electron pp. 559-560

V. Alan Kostelecký

CRISPR engineering turns on genes pp. 560-562

Seung Woo Cho and Howard Y. Chang

Free and forced climate variations pp. 562-563

James Risbey

Risk factors and random chances pp. 563-564

Dominik Wodarz and Ann G. Zauber

Forcing, feedback and internal variability in global temperature trends pp. 565-570

Jochem Marotzke and Piers M. Forster

An Arabidopsis gene regulatory network for secondary cell wall synthesis pp. 571-575

M. Taylor-Teeples, L. Lin, M. de Lucas, G. Turco, T. W. Toal, A. Gaudinier, N. F. Young, G. M. Trabucco, M. T. Veling, R. Lamothe, P. P. Handakumbura, G. Xiong, C. Wang, J. Corwin, A. Tsoukalas, L. Zhang, D. Ware, M. Pauly, D. J. Kliebenstein, K. Dehesh, I. Tagkopoulos, G. Breton, J. L. Pruneda-Paz, S. E. Ahnert, S. A. Kay, S. P. Hazen and S. M. Brady

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex pp. 583-588

Silvana Konermann, Mark D. Brigham, Alexandro E. Trevino, Julia Joung, Omar O. Abudayyeh, Clea Barcena, Patrick D. Hsu, Naomi Habib, Jonathan S. Gootenberg, Hiroshi Nishimasu, Osamu Nureki and Feng Zhang

A spin-down clock for cool stars from observations of a 2.5-billion-year-old cluster pp. 589-591

Søren Meibom, Sydney A. Barnes, Imants Platais, Ronald L. Gilliland, David W. Latham and Robert D. Mathieu

Michelson–Morley analogue for electrons using trapped ions to test Lorentz symmetry pp. 592-595

T. Pruttivarasin, M. Ramm, S. G. Porsev, I. I. Tupitsyn, M. S. Safronova, M. A. Hohensee and H. Häffner

Anomalous dispersions of ‘hedgehog’ particles pp. 596-599

Joong Hwan Bahng, Bongjun Yeom, Yichun Wang, Siu On Tung, J. Damon Hoff and Nicholas Kotov

Metal-catalysed azidation of tertiary C–H bonds suitable for late-stage functionalization pp. 600-604

Ankit Sharma and John F. Hartwig

Effects of electron correlations on transport properties of iron at Earth’s core conditions pp. 605-607

Peng Zhang, R. E. Cohen and K. Haule

Resolving the complexity of the human genome using single-molecule sequencing pp. 608-611

Mark J. P. Chaisson, John Huddleston, Megan Y. Dennis, Peter H. Sudmant, Maika Malig, Fereydoun Hormozdiari, Francesca Antonacci, Urvashi Surti, Richard Sandstrom, Matthew Boitano, Jane M. Landolin, John A. Stamatoyannopoulos, Michael W. Hunkapiller, Jonas Korlach and Evan E. Eichler

Interception of host angiogenic signalling limits mycobacterial growth pp. 612-615

Stefan H. Oehlers, Mark R. Cronan, Ninecia R. Scott, Monica I. Thomas, Kazuhide S. Okuda, Eric M. Walton, Rebecca W. Beerman, Philip S. Crosier and David M. Tobin

p63+Krt5+ distal airway stem cells are essential for lung regeneration pp. 616-620

Wei Zuo, Ting Zhang, Daniel Zheng'An Wu, Shou Ping Guan, Audrey-Ann Liew, Yusuke Yamamoto, Xia Wang, Siew Joo Lim, Matthew Vincent, Mark Lessard, Christopher P. Crum, Wa Xian and Frank McKeon

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury pp. 621-625

Andrew E. Vaughan, Alexis N. Brumwell, Ying Xi, Jeffrey E. Gotts, Doug G. Brownfield, Barbara Treutlein, Kevin Tan, Victor Tan, Feng Chun Liu, Mark R. Looney, Michael A. Matthay, Jason R. Rock and Harold A. Chapman

IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo pp. 626-630

Avinashnarayan Venkatanarayan, Payal Raulji, William Norton, Deepavali Chakravarti, Cristian Coarfa, Xiaohua Su, Santosh K. Sandur, Marc S. Ramirez, Jaehuk Lee, Charles V. Kingsley, Eliot F. Sananikone, Kimal Rajapakshe, Katherine Naff, Jan Parker-Thornburg, James A. Bankson, Kenneth Y. Tsai, Preethi H. Gunaratne and Elsa R. Flores

The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C pp. 631-634

Daisuke Izawa and Jonathon Pines

Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide pp. 635-639

Bret D. Freudenthal, William A. Beard, Lalith Perera, David D. Shock, Taejin Kim, Tamar Schlick and Samuel H. Wilson

Structural insight into autoinhibition and histone H3-induced activation of DNMT3A pp. 640-644

Xue Guo, Ling Wang, Jie Li, Zhanyu Ding, Jianxiong Xiao, Xiaotong Yin, Shuang He, Pan Shi, Liping Dong, Guohong Li, Changlin Tian, Jiawei Wang, Yao Cong and Yanhui Xu

Career counselling: Pick a path pp. 645-647

Neil Savage

The puppet pp. 650-650

Michael Adam Robson

2015, volume 517, articles 7535

Effective risk response needs a prepared mindset pp. 413-413

Erwann Michel-Kerjan

A case for a university happiness ranking pp. 415-415

Chris Woolston

Attempts to predict terrorist attacks hit limits pp. 419-420

Quirin Schiermeier

Psychologists seek roots of terror pp. 420-421

Sara Reardon

Crunch time for pet theory on dark matter pp. 422-423

Davide Castelvecchi

GM microbes created that can’t escape the lab pp. 423-423

Elie Dolgin

CalWater 2015 targets atmospheric rivers off California pp. 424-425

Alexandra Witze

Ageing research: Blood to blood pp. 426-429

Megan Scudellari

Astronomy: Laser focus pp. 430-432

Ann Finkbeiner

Policy: Four gaps in China's new environmental law pp. 433-434

Bo Zhang and Cong Cao

Big data: Stealth control pp. 435-436

Steven Aftergood

Ageing: Eternal obsession pp. 436-437

Monya Baker

Books in brief pp. 437-437

Barbara Kiser

Spread excellence across Europe pp. 438-438

Maciej Żylicz

Indirect costs: Cash is no gravy train pp. 438-438

David Korn

Indirect costs: The reimbursement gap pp. 438-438

Paul R. Sanberg, Judy Genshaft and Sudeep Sarkar

Disaster mapping by citizens is limited pp. 438-438

Norman Kerle

Bold alliances aid translational work pp. 438-438

Janine T. Erler

Gold unleashes the power of three pp. 440-441

Christopher M. B. K. Kourra and Nicolai Cramer

Hold on and let go pp. 441-442

Kikuë Tachibana-Konwalski

An irresistible newcomer pp. 442-444

Gerard Wright

Cosmic fog and smog pp. 444-445

Molly S. Peeples

Monsoon matters pp. 445-446

Bronwen Konecky

On the endocytosis rollercoaster pp. 446-447

Volker Haucke

Stable gold(III) catalysts by oxidative addition of a carbon–carbon bond pp. 449-454

Chung-Yeh Wu, Takahiro Horibe, Christian Borch Jacobsen and F. Dean Toste

A new antibiotic kills pathogens without detectable resistance pp. 455-459

Losee L. Ling, Tanja Schneider, Aaron J. Peoples, Amy L. Spoering, Ina Engels, Brian P. Conlon, Anna Mueller, Till F. Schäberle, Dallas E. Hughes, Slava Epstein, Michael Jones, Linos Lazarides, Victoria A. Steadman, Douglas R. Cohen, Cintia R. Felix, K. Ashley Fetterman, William P. Millett, Anthony G. Nitti, Ashley M. Zullo, Chao Chen and Kim Lewis

Endophilin marks and controls a clathrin-independent endocytic pathway pp. 460-465

Emmanuel Boucrot, Antonio P. A. Ferreira, Leonardo Almeida-Souza, Sylvain Debard, Yvonne Vallis, Gillian Howard, Laetitia Bertot, Nathalie Sauvonnet and Harvey T. McMahon

Meikin is a conserved regulator of meiosis-I-specific kinetochore function pp. 466-471

Jihye Kim, Kei-ichiro Ishiguro, Aya Nambu, Bungo Akiyoshi, Shihori Yokobayashi, Ayano Kagami, Tadashi Ishiguro, Alberto M. Pendas, Naoki Takeda, Yogo Sakakibara, Tomoya S. Kitajima, Yuji Tanno, Takeshi Sakuno and Yoshinori Watanabe

Long-lived magnetism from solidification-driven convection on the pallasite parent body pp. 472-475

James F. J. Bryson, Claire I. O. Nichols, Julia Herrero-Albillos, Florian Kronast, Takeshi Kasama, Hossein Alimadadi, Gerrit van der Laan, Francis Nimmo and Richard J. Harrison

Compositional engineering of perovskite materials for high-performance solar cells pp. 476-480

Nam Joong Jeon, Jun Hong Noh, Woon Seok Yang, Young Chan Kim, Seungchan Ryu, Jangwon Seo and Sang Il Seok

Probabilistic reanalysis of twentieth-century sea-level rise pp. 481-484

Carling C. Hay, Eric Morrow, Robert Kopp and Jerry X. Mitrovica

A basal ichthyosauriform with a short snout from the Lower Triassic of China pp. 485-488

Ryosuke Motani, Da-Yong Jiang, Guan-Bao Chen, Andrea Tintori, Olivier Rieppel, Cheng Ji and Jian-Dong Huang

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer pp. 489-492

Peter M. K. Westcott, Kyle D. Halliwill, Minh D. To, Mamunur Rashid, Alistair G. Rust, Thomas M. Keane, Reyno Delrosario, Kuang-Yu Jen, Kay E. Gurley, Christopher J. Kemp, Erik Fredlund, David A. Quigley, David J. Adams and Allan Balmain

Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis pp. 493-496

Henri-François Renard, Mijo Simunovic, Joël Lemière, Emmanuel Boucrot, Maria Daniela Garcia-Castillo, Senthil Arumugam, Valérie Chambon, Christophe Lamaze, Christian Wunder, Anne K. Kenworthy, Anne A. Schmidt, Harvey T. McMahon, Cécile Sykes, Patricia Bassereau and Ludger Johannes

mTORC1-mediated translational elongation limits intestinal tumour initiation and growth pp. 497-500

William J. Faller, Thomas J. Jackson, John R. P. Knight, Rachel A. Ridgway, Thomas Jamieson, Saadia A. Karim, Carolyn Jones, Sorina Radulescu, David J. Huels, Kevin B. Myant, Kate M. Dudek, Helen A. Casey, Alessandro Scopelliti, Julia B. Cordero, Marcos Vidal, Mario Pende, Alexey G. Ryazanov, Nahum Sonenberg, Oded Meyuhas, Michael N. Hall, Martin Bushell, Anne E. Willis and Owen J. Sansom

IgG1 protects against renal disease in a mouse model of cryoglobulinaemia pp. 501-504

Richard T. Strait, Monica T. Posgai, Ashley Mahler, Nathaniel Barasa, Chaim O. Jacob, Jörg Köhl, Marc Ehlers, Keith Stringer, Shiva Kumar Shanmukhappa, David Witte, Md Monir Hossain, Marat Khodoun, Andrew B. Herr and Fred D. Finkelman

Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution pp. 505-508

Florian K. M. Schur, Wim J. H. Hagen, Michaela Rumlová, Tomáš Ruml, Barbara Müller, Hans-Georg Kräusslich and John A. G. Briggs

Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB pp. 509-512

Manuel A. Ortega, Yue Hao, Qi Zhang, Mark C. Walker, Wilfred A. van der Donk and Satish K. Nair

Reductive dehalogenase structure suggests a mechanism for B12-dependent dehalogenation pp. 513-516

Karl A. P. Payne, Carolina P. Quezada, Karl Fisher, Mark S. Dunstan, Fraser A. Collins, Hanno Sjuts, Colin Levy, Sam Hay, Stephen E. J. Rigby and David Leys

Time management: Seize the moment pp. 517-519

Jeffrey M. Perkel

Turning point: Swati Padmaraj pp. 519-519

Scott Kraft

Treatment naive pp. 522-522

Steve Zisson

2015, volume 517, articles 7534

The focus on bibliometrics makes papers less useful pp. 245-245

Reinhard Werner

What would happen if grant reviews were made public? pp. 247-247

Chris Woolston

Political appointments spur concerns for Amazon pp. 251-252

Jeff Tollefson

‘I can haz genomes’: cats claw their way into genetics pp. 252-253

Ewen Callaway

First biosimilar drug set to enter US market pp. 253-254

Heidi Ledford

Blown-up brains reveal nanoscale details pp. 254-254

Ewen Callaway

Tropical paradise inspires virtual ecology lab pp. 255-256

Daniel Cressey

Al Gore’s dream spacecraft gears up for launch pp. 256-257

Mark Zastrow

Agriculture: State-of-the-art soil pp. 258-260

Rachel Cernansky

Microbiology: Here's looking at you, squid pp. 262-264

Ed Yong

Human adaptation: Manage climate-induced resettlement pp. 265-267

David López-Carr and Jessica Marter-Kenyon

Science policy: From Brookhaven to Bush pp. 268-269

Peter Gluckman

History of chemistry: Words into gold pp. 269-269

Philip Ball

Giant tortoises hatch on Galapagos island pp. 271-271

Washington Tapia Aguilera, Jeffreys Málaga and James P. Gibbs

Natural history: save Italy's museums pp. 271-271

Franco Andreone

Natural history: first museologist's legacy pp. 271-271

Marco Romano, Richard L. Cifelli and Gian Battista Vai

Use mentoring to fix science inequality pp. 271-271

Malgorzata Blicharska and Grzegorz Mikusiński

IPBES responds on conflicts of interest pp. 271-271

Anne Larigauderie

Alexander Grothendieck (1928–2014) pp. 272-272

David Mumford and John Tate

Boxed up and ready to go pp. 274-275

Stacy C. Farina and Adam P. Summers

Mixing it up in the mantle pp. 275-276

Jon Woodhead

African dawn pp. 276-277

Raj Ramesar

Hydrophobic interactions in context pp. 277-279

Shekhar Garde

Dragonflies predict and plan their hunts pp. 279-280

Stacey A. Combes

One catalyst, two reactions pp. 280-281

Emmanuelle Schulz

Seeking ultimate victory pp. 281-282

Louis J. Picker and Jeffrey D. Lifson

Frontiers in biology pp. 283-283

Alex Eccleston, Noah Gray, Sadaf Shadan and Ursula Weiss

From circuits to behaviour in the amygdala pp. 284-292

Patricia H. Janak and Kay M. Tye

The biology of innate lymphoid cells pp. 293-301

David Artis and Hergen Spits

Nutrient-sensing mechanisms and pathways pp. 302-310

Alejo Efeyan, William C. Comb and David M. Sabatini

Necroptosis and its role in inflammation pp. 311-320

Manolis Pasparakis and Peter Vandenabeele

Function and information content of DNA methylation pp. 321-326

Dirk Schübeler

The African Genome Variation Project shapes medical genetics in Africa pp. 327-332

Deepti Gurdasani, Tommy Carstensen, Fasil Tekola-Ayele, Luca Pagani, Ioanna Tachmazidou, Konstantinos Hatzikotoulas, Savita Karthikeyan, Louise Iles, Martin O. Pollard, Ananyo Choudhury, Graham R. S. Ritchie, Yali Xue, Jennifer Asimit, Rebecca N. Nsubuga, Elizabeth H. Young, Cristina Pomilla, Katja Kivinen, Kirk Rockett, Anatoli Kamali, Ayo P. Doumatey, Gershim Asiki, Janet Seeley, Fatoumatta Sisay-Joof, Muminatou Jallow, Stephen Tollman, Ephrem Mekonnen, Rosemary Ekong, Tamiru Oljira, Neil Bradman, Kalifa Bojang, Michele Ramsay, Adebowale Adeyemo, Endashaw Bekele, Ayesha Motala, Shane A. Norris, Fraser Pirie, Pontiano Kaleebu, Dominic Kwiatkowski, Chris Tyler-Smith, Charles Rotimi, Eleftheria Zeggini and Manjinder S. Sandhu

Internal models direct dragonfly interception steering pp. 333-338

Matteo Mischiati, Huai-Ti Lin, Paul Herold, Elliot Imler, Robert Olberg and Anthony Leonardo

Impact jetting as the origin of chondrules pp. 339-341

Brandon C. Johnson, David A. Minton, H. J. Melosh and Maria T. Zuber

Direct observation of electron propagation and dielectric screening on the atomic length scale pp. 342-346

S. Neppl, R. Ernstorfer, A. L. Cavalieri, C. Lemell, G. Wachter, E. Magerl, E. M. Bothschafter, M. Jobst, M. Hofstetter, U. Kleineberg, J. V. Barth, D. Menzel, J. Burgdörfer, P. Feulner, F. Krausz and R. Kienberger

Modulation of hydrophobic interactions by proximally immobilized ions pp. 347-350

C. Derek Ma, Chenxuan Wang, Claribel Acevedo-Vélez, Samuel H. Gellman and Nicholas L. Abbott

Non-stabilized nucleophiles in Cu-catalysed dynamic kinetic asymmetric allylic alkylation pp. 351-355

Hengzhi You, Emeline Rideau, Mireia Sidera and Stephen P. Fletcher

The terrestrial uranium isotope cycle pp. 356-359

Morten B. Andersen, Tim Elliott, Heye Freymuth, Kenneth W. W. Sims, Yaoling Niu and Katherine A. Kelley

Promoterless gene targeting without nucleases ameliorates haemophilia B in mice pp. 360-364

A. Barzel, N. K. Paulk, Y. Shi, Y. Huang, K. Chu, F. Zhang, P. N. Valdmanis, L. P. Spector, M. H. Porteus, K. M. Gaensler and M. A. Kay

Productivity limits and potentials of the principles of conservation agriculture pp. 365-368

Cameron M. Pittelkow, Xinqiang Liang, Bruce A. Linquist, Kees Jan van Groenigen, Juhwan Lee, Mark E. Lundy, Natasja van Gestel, Johan Six, Rodney T. Venterea and Chris van Kessel

Long-term phenotypic evolution of bacteria pp. 369-372

Germán Plata, Christopher S. Henry and Dennis Vitkup

The neural representation of taste quality at the periphery pp. 373-376

Robert P. J. Barretto, Sarah Gillis-Smith, Jayaram Chandrashekar, David A. Yarmolinsky, Mark J. Schnitzer, Nicholas J. P. Ryba and Charles S. Zuker

Control of plant stem cell function by conserved interacting transcriptional regulators pp. 377-380

Yun Zhou, Xing Liu, Eric M. Engstrom, Zachary L. Nimchuk, Jose L. Pruneda-Paz, Paul T. Tarr, An Yan, Steve A. Kay and Elliot M. Meyerowitz

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations pp. 381-385

Kai Deng, Mihaela Pertea, Anthony Rongvaux, Leyao Wang, Christine M. Durand, Gabriel Ghiaur, Jun Lai, Holly L. McHugh, Haiping Hao, Hao Zhang, Joseph B. Margolick, Cagan Gurer, Andrew J. Murphy, David M. Valenzuela, George D. Yancopoulos, Steven G. Deeks, Till Strowig, Priti Kumar, Janet D. Siliciano, Steven L. Salzberg, Richard A. Flavell, Liang Shan and Robert F. Siliciano

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion pp. 386-390

Yu-Hwa Huang, Chen Zhu, Yasuyuki Kondo, Ana C. Anderson, Amit Gandhi, Andrew Russell, Stephanie K. Dougan, Britt-Sabina Petersen, Espen Melum, Thomas Pertel, Kiera L. Clayton, Monika Raab, Qiang Chen, Nicole Beauchemin, Paul J. Yazaki, Michal Pyzik, Mario A. Ostrowski, Jonathan N. Glickman, Christopher E. Rudd, Hidde L. Ploegh, Andre Franke, Gregory A. Petsko, Vijay K. Kuchroo and Richard S. Blumberg

An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ pp. 391-395

Alexander S. Banks, Fiona E. McAllister, João Paulo G. Camporez, Peter-James H. Zushin, Michael J. Jurczak, Dina Laznik-Bogoslavski, Gerald I. Shulman, Steven P. Gygi and Bruce M. Spiegelman

Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter pp. 396-400

JungMin Kim, Shenping Wu, Thomas M. Tomasiak, Claudia Mergel, Michael B. Winter, Sebastian B. Stiller, Yaneth Robles-Colmanares, Robert M. Stroud, Robert Tampé, Charles S. Craik and Yifan Cheng

Work–life balance: Lab life with kids pp. 401-403

Kendall Powell

The left hands of lovers pp. 406-406

Emily Eckart

2015, volume 517, articles 7533

Economic divide taking toll on European science pp. 123-123

Colin Macilwain

Word-processing war flares up on social media pp. 125-125

Chris Woolston

Greek science haunted by hydra of problems pp. 127-128

Alison Abbott

End of cancer-genome project prompts rethink pp. 128-129

Heidi Ledford

South Korean survey ships open up to science pp. 129-130

Mark Zastrow

Rave drug holds promise for treating depression fast pp. 130-131

Sara Reardon

Military health: The insurmountable gulf pp. 132-134

Sara Reardon

Environmental science: Pollution patrol pp. 136-138

Kat Austen

Immunology: Fifty years of B lymphocytes pp. 139-141

Alexander D. Gitlin and Michel C. Nussenzweig

Mineralogy: Painful extractions pp. 142-143

Andrew Bloodworth

Books in brief pp. 143-143

Barbara Kiser

Resources: Silt, dams and hydraulic heroes pp. 144-144

Philip Ball

Peer review as a business transaction pp. 145-145

Eleftherios P. Diamandis

Pollution: Uncouple from economy boom pp. 145-145

Hong-Wei Xiao, A. S. Mujumdar and Liming Che

Pollution: Clear blue skies over Beijing pp. 145-145

Zhaohui Gong

Pollution: Build on success in China pp. 145-145

Yansui Liu, Yuheng Li and Cong Chen

International Council for Science responds pp. 145-145

Gordon McBean

Carbon at the coastal interface pp. 148-149

Nicolas Gruber

Enzymes surf the heat wave pp. 149-150

A. Joshua Wand

Unburnable fossil-fuel reserves pp. 150-151

Michael Jakob and Jérôme Hilaire

Resistance through repopulation pp. 152-153

Ian F. Tannock

Spin memories in for the long haul pp. 153-154

John J. L. Morton and Klaus Mølmer

The versatile and plastic liver pp. 155-156

Meritxell Huch

A three-dimensional neural compass pp. 156-157

David C. Rowland and May-Britt Moser

Three-dimensional head-direction coding in the bat brain pp. 159-164

Arseny Finkelstein, Dori Derdikman, Alon Rubin, Jakob N. Foerster, Liora Las and Nachum Ulanovsky

Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism pp. 165-169

Fiona Cuskin, Elisabeth C. Lowe, Max J. Temple, Yanping Zhu, Elizabeth A. Cameron, Nicholas A. Pudlo, Nathan T. Porter, Karthik Urs, Andrew J. Thompson, Alan Cartmell, Artur Rogowski, Brian S. Hamilton, Rui Chen, Thomas J. Tolbert, Kathleen Piens, Debby Bracke, Wouter Vervecken, Zalihe Hakki, Gaetano Speciale, Jose L. Munōz-Munōz, Andrew Day, Maria J. Peña, Richard McLean, Michael D. Suits, Alisdair B. Boraston, Todd Atherly, Cherie J. Ziemer, Spencer J. Williams, Gideon J. Davies, D. Wade Abbott, Eric C. Martens and Harry J. Gilbert

Glutathione activates virulence gene expression of an intracellular pathogen pp. 170-173

Michelle L. Reniere, Aaron T. Whiteley, Keri L. Hamilton, Sonya M. John, Peter Lauer, Richard G. Brennan and Daniel A. Portnoy

The temperature and chronology of heavy-element synthesis in low-mass stars pp. 174-176

P. Neyskens, S. Van Eck, A. Jorissen, S. Goriely, L. Siess and B. Plez

Optically addressable nuclear spins in a solid with a six-hour coherence time pp. 177-180

Manjin Zhong, Morgan P. Hedges, Rose L. Ahlefeldt, John G. Bartholomew, Sarah E. Beavan, Sven M. Wittig, Jevon J. Longdell and Matthew J. Sellars

High-value alcohols and higher-oxidation-state compounds by catalytic Z-selective cross-metathesis pp. 181-186

Ming Joo Koh, R. Kashif M. Khan, Sebastian Torker, Miao Yu, Malte S. Mikus and Amir H. Hoveyda

The geographical distribution of fossil fuels unused when limiting global warming to 2 °C pp. 187-190

Christophe McGlade and Paul Ekins

Segmented lateral dyke growth in a rifting event at Bárðarbunga volcanic system, Iceland pp. 191-195

Freysteinn Sigmundsson, Andrew Hooper, Sigrún Hreinsdóttir, Kristín S. Vogfjörd, Benedikt G. Ófeigsson, Elías Rafn Heimisson, Stéphanie Dumont, Michelle Parks, Karsten Spaans, Gunnar B. Gudmundsson, Vincent Drouin, Thóra Árnadóttir, Kristín Jónsdóttir, Magnús T. Gudmundsson, Thórdís Högnadóttir, Hildur María Fridriksdóttir, Martin Hensch, Páll Einarsson, Eyjólfur Magnússon, Sergey Samsonov, Bryndís Brandsdóttir, Robert S. White, Thorbjörg Ágústsdóttir, Tim Greenfield, Robert G. Green, Ásta Rut Hjartardóttir, Rikke Pedersen, Richard A. Bennett, Halldór Geirsson, Peter C. La Femina, Helgi Björnsson, Finnur Pálsson, Erik Sturkell, Christopher J. Bean, Martin Möllhoff, Aoife K. Braiden and Eva P. S. Eibl

Copulation in antiarch placoderms and the origin of gnathostome internal fertilization pp. 196-199

John A. Long, Elga Mark-Kurik, Zerina Johanson, Michael S. Y. Lee, Gavin C. Young, Zhu Min, Per E. Ahlberg, Michael Newman, Roger Jones, Jan den Blaauwen, Brian Choo and Kate Trinajstic

Calcium transient prevalence across the dendritic arbour predicts place field properties pp. 200-204

Mark E. J. Sheffield and Daniel A. Dombeck

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile pp. 205-208

Charlie G. Buffie, Vanni Bucci, Richard R. Stein, Peter T. McKenney, Lilan Ling, Asia Gobourne, Daniel No, Hui Liu, Melissa Kinnebrew, Agnes Viale, Eric Littmann, Marcel R. M. van den Brink, Robert R. Jenq, Ying Taur, Chris Sander, Justin R. Cross, Nora C. Toussaint, Joao B. Xavier and Eric G. Pamer

Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance pp. 209-213

Antonina V. Kurtova, Jing Xiao, Qianxing Mo, Senthil Pazhanisamy, Ross Krasnow, Seth P. Lerner, Fengju Chen, Terrence T. Roh, Erica Lay, Philip Levy Ho and Keith Syson Chan

T–B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction pp. 214-218

Dan Liu, Heping Xu, Changming Shih, Zurong Wan, Xiaopeng Ma, Weiwei Ma, Dan Luo and Hai Qi

EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway pp. 219-222

Brent Neumann, Sean Coakley, Rosina Giordano-Santini, Casey Linton, Eui Seung Lee, Akihisa Nakagawa, Ding Xue and Massimo A. Hilliard

Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal pp. 223-226

Paul A. DaRosa, Zhizhi Wang, Xiaomo Jiang, Jonathan N. Pruneda, Feng Cong, Rachel E. Klevit and Wenqing Xu

The heat released during catalytic turnover enhances the diffusion of an enzyme pp. 227-230

Clement Riedel, Ronen Gabizon, Christian A. M. Wilson, Kambiz Hamadani, Konstantinos Tsekouras, Susan Marqusee, Steve Pressé and Carlos Bustamante

Outreach: Speak up for science pp. 231-233

Virginia Gewin

The descent of man pp. 236-236

Christoph Weber

2015, volume 517, articles 7532

The rising pressure of global water shortages pp. 6-6

Jan Eliasson

Nicaragua defies canal protests pp. 7-8

Lucas Laursen

Planet hunters plot course for habitable worlds pp. 8-9

Alexandra Witze

Ebola raises profile of blood-based therapy pp. 9-10

Declan Butler

What to expect in 2015 pp. 10-11

Elizabeth Gibney

Science in 2015 pp. 12-13

Mark Zastrow

Listings: Science in culture 2015 pp. 18-20

Daniel Cressey

New law risks release of invasive species pp. 21-21

Philip E. Hulme

Harmful soot spurs climate-policy action pp. 21-21

David G. Victor, V. Ramanathan and Durwood Zaelke

Green heating plan threatens air quality pp. 21-21

Gordon McFiggans

Criteria for Nature Index questioned pp. 21-21

Robin Haunschild and Lutz Bornmann

Paul von Ragué Schleyer (1930–2014) pp. 22-22

Henry F. Schaefer

Entry signals control development pp. 24-25

Jonathan D. Dinman

Like cartilage, but simpler pp. 25-26

Anne Ladegaard Skov

Photosynthetic complex in close-up pp. 26-27

Ilme Schlichting

Diverted on the way to memory pp. 28-29

Gordon Y. C. Cheung and Michael Otto

It takes three to find the exit pp. 29-30

Mathieu Bollen

Ocean circulation and rapid climate change pp. 30-31

Ellen E. Martin

RNA regulons in Hox 5′ UTRs confer ribosome specificity to gene regulation pp. 33-38

Shifeng Xue, Siqi Tian, Kotaro Fujii, Wipapat Kladwang, Rhiju Das and Maria Barna

Architecture and conformational switch mechanism of the ryanodine receptor pp. 39-43

Rouslan G. Efremov, Alexander Leitner, Ruedi Aebersold and Stefan Raunser

Structure of a mammalian ryanodine receptor pp. 44-49

Ran Zalk, Oliver B. Clarke, Amédée des Georges, Robert A. Grassucci, Steven Reiken, Filippo Mancia, Wayne A. Hendrickson, Joachim Frank and Andrew R. Marks

Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution pp. 50-55

Zhen Yan, Xiao-chen Bai, Chuangye Yan, Jianping Wu, Zhangqiang Li, Tian Xie, Wei Peng, Chang-cheng Yin, Xueming Li, Sjors H. W. Scheres, Yigong Shi and Nieng Yan

A higher-than-predicted measurement of iron opacity at solar interior temperatures pp. 56-59

J. E. Bailey, T. Nagayama, G. P. Loisel, G. A. Rochau, C. Blancard, J. Colgan, Ph. Cosse, G. Faussurier, C. J. Fontes, F. Gilleron, I. Golovkin, S. B. Hansen, C. A. Iglesias, D. P. Kilcrease, J. J. MacFarlane, R. C. Mancini, S. N. Nahar, C. Orban, J.-C. Pain, A. K. Pradhan, M. Sherrill and B. G. Wilson

Higher-than-predicted saltation threshold wind speeds on Titan pp. 60-63

Devon M. Burr, Nathan T. Bridges, John R. Marshall, James K. Smith, Bruce R. White and Joshua P. Emery

Observation of quantized conductance in neutral matter pp. 64-67

Sebastian Krinner, David Stadler, Dominik Husmann, Jean-Philippe Brantut and Tilman Esslinger

An anisotropic hydrogel with electrostatic repulsion between cofacially aligned nanosheets pp. 68-72

Mingjie Liu, Yasuhiro Ishida, Yasuo Ebina, Takayoshi Sasaki, Takaaki Hikima, Masaki Takata and Takuzo Aida

Strong and deep Atlantic meridional overturning circulation during the last glacial cycle pp. 73-76

E. Böhm, J. Lippold, M. Gutjahr, M. Frank, P. Blaser, B. Antz, J. Fohlmeister, N. Frank, M. B. Andersen and M. Deininger

Origins of major archaeal clades correspond to gene acquisitions from bacteria pp. 77-80

Shijulal Nelson-Sathi, Filipa L. Sousa, Mayo Roettger, Nabor Lozada-Chávez, Thorsten Thiergart, Arnold Janssen, David Bryant, Giddy Landan, Peter Schönheit, Bettina Siebers, James O. McInerney and William F. Martin

Identification of multipotent mammary stem cells by protein C receptor expression pp. 81-84

Daisong Wang, Cheguo Cai, Xiaobing Dong, Qing Cissy Yu, Xiao-Ou Zhang, Li Yang and Yi Arial Zeng

Hepatitis A virus and the origins of picornaviruses pp. 85-88

Xiangxi Wang, Jingshan Ren, Qiang Gao, Zhongyu Hu, Yao Sun, Xuemei Li, David J. Rowlands, Weidong Yin, Junzhi Wang, David I. Stuart, Zihe Rao and Elizabeth E. Fry

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation pp. 89-93

Xianqin Zhang, Dusan Bogunovic, Béatrice Payelle-Brogard, Véronique Francois-Newton, Scott D. Speer, Chao Yuan, Stefano Volpi, Zhi Li, Ozden Sanal, Davood Mansouri, Ilhan Tezcan, Gillian I. Rice, Chunyuan Chen, Nahal Mansouri, Seyed Alireza Mahdaviani, Yuval Itan, Bertrand Boisson, Satoshi Okada, Lu Zeng, Xing Wang, Hui Jiang, Wenqiang Liu, Tiantian Han, Delin Liu, Tao Ma, Bo Wang, Mugen Liu, Jing-Yu Liu, Qing K. Wang, Dilek Yalnizoglu, Lilliana Radoshevich, Gilles Uzé, Philippe Gros, Flore Rozenberg, Shen-Ying Zhang, Emmanuelle Jouanguy, Jacinta Bustamante, Adolfo García-Sastre, Laurent Abel, Pierre Lebon, Luigi D. Notarangelo, Yanick J. Crow, Stéphanie Boisson-Dupuis, Jean-Laurent Casanova and Sandra Pellegrini

A PP1–PP2A phosphatase relay controls mitotic progression pp. 94-98

Agnes Grallert, Elvan Boke, Anja Hagting, Ben Hodgson, Yvonne Connolly, John R. Griffiths, Duncan L. Smith, Jonathon Pines and Iain M. Hagan

Native structure of photosystem II at 1.95 Å resolution viewed by femtosecond X-ray pulses pp. 99-103

Michihiro Suga, Fusamichi Akita, Kunio Hirata, Go Ueno, Hironori Murakami, Yoshiki Nakajima, Tetsuya Shimizu, Keitaro Yamashita, Masaki Yamamoto, Hideo Ago and Jian-Ren Shen

Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum pp. 104-107

Xiaochun Li, Rita Roberti and Günter Blobel

Programming tools: Adventures with R pp. 109-110

Sylvia Tippmann

Hopes for the year ahead pp. 111-113

Monya Baker

Infraction pp. 116-116

John Gilbey