Local regulation of gene expression by lncRNA promoters, transcription and splicing

Jesse M. Engreitz, Jenna E. Haines, Elizabeth M. Perez, Glen Munson, Jenny Chen, Michael Kane, Patrick E. McDonel, Mitchell Guttman and Eric S. Lander ()
Additional contact information
Jesse M. Engreitz: Broad Institute of MIT and Harvard
Jenna E. Haines: Broad Institute of MIT and Harvard
Elizabeth M. Perez: Broad Institute of MIT and Harvard
Glen Munson: Broad Institute of MIT and Harvard
Jenny Chen: Broad Institute of MIT and Harvard
Michael Kane: Broad Institute of MIT and Harvard
Patrick E. McDonel: Broad Institute of MIT and Harvard
Mitchell Guttman: California Institute of Technology
Eric S. Lander: Broad Institute of MIT and Harvard

Nature, 2016, vol. 539, issue 7629, 452-455

Abstract: Various cis-regulatory functions of genomic loci that produce long non-coding RNAs are revealed, including instances where their promoters have enhancer-like activity and the lncRNA transcripts themselves are not required for activity.

Date: 2016
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://www.nature.com/articles/nature20149 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:539:y:2016:i:7629:d:10.1038_nature20149

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature20149

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().