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2010, volume 466, articles 7310

Parkinson's disease pp. S1-S1

Michelle Grayson

Secrets of the shaking palsy pp. S2-S5

Jim Schnabel

Levodopa: the story so far pp. S6-S7

Alison Abbott

Parkinson's disease: a model dilemma pp. S8-S10

M. Flint Beal

Biomarkers: casting the net wide pp. S11-S12

Rachel Jones

Evidence for male allocation in pipefish? pp. E11-E11

Darryl T. Gwynne, Kevin A. Judge and Clint D. Kelly

Paczolt & Jones reply pp. E12-E12

Kimberly A. Paczolt and Adam G. Jones

Slowing the decline pp. S13-S14

Ruth Williams

Treatment frontiers pp. S15-S18

Kerri Smith

Journal club pp. 1025-1025

Richard E. Zeebe

Big science feels the pinch in Europe pp. 1028-1029

Geoff Brumfiel

Sugar synthesis speeds up pp. 1029-1029

Richard Van Noorden

G-whizzes disagree over gravity pp. 1030-1030

Eugenie Samuel Reich

Key Alzheimer's findings questioned pp. 1031-1031

Heidi Ledford

Battle to degas deadly lakes continues pp. 1033-1033

Nicola Jones

Nuclear theory nudged pp. 1034-1034

Eugenie Samuel Reich

Genetics: Pet project pp. 1036-1038

David Cyranoski

Consumers have a right to affordable genetic testing pp. 1040-1040

Christopher Kanan

Misconduct: don't assume science is self-correcting pp. 1040-1040

Thomas P. Hettinger

Misconduct: don't penalize the honest majority of scientists pp. 1040-1040

John P. Moore

Proposals for surface-temperature databank now open for scrutiny pp. 1040-1040

Peter Stott and Peter Thorne

Clarifying knowledge ownership in Europe's medicines initiative pp. 1040-1041

Kim De Rijck and Michel Goldman

Mosquitoes: schemes to render them extinct are impracticable pp. 1041-1041

Stephen M. Smith

Mosquitoes: first evaluate impacts of eradicating them pp. 1041-1041

Jon D. Hoekstra

Mosquitoes: retain an ex situ population for ecological insurance pp. 1041-1041

Ben Phalan

Mosquitoes: just how much biodiversity does humanity need? pp. 1041-1041

Fern Wickson

Disasters widen the rich–poor gap pp. 1042-1042

John Mutter

Save your census pp. 1043-1043

Stephen E. Fienberg and Kenneth Prewitt

Last days of the lone astronomer pp. 1044-1045

Joss Bland-Hawthorn

Preserving social difference pp. 1045-1045

Andrew Robinson

Japanese view of the natural world pp. 1046-1046

David Cyranoski

The dance of electrons and holes pp. 1047-1048

Gregory D. Scholes

Conservation in vesicle coats pp. 1048-1049

Stephen C. Harrison and Tomas Kirchhausen

Making black holes from scratch pp. 1049-1050

Marta Volonteri

Retinoblastoma, a trip organizer pp. 1051-1052

Giovanni Bosco

An expansion in ALS genetics pp. 1052-1053

Clotilde Lagier-Tourenne and Don W. Cleveland

The usefulness of uselessness pp. 1053-1054

Andreas Winter

Viruses' backup plan pp. 1054-1055

Kevin M. Ryan

The evolution of eusociality pp. 1057-1062

Martin A. Nowak, Corina E. Tarnita and Edward O. Wilson

Lithospheric layering in the North American craton pp. 1063-1068

Huaiyu Yuan and Barbara Romanowicz

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS pp. 1069-1075

Andrew C. Elden, Hyung-Jun Kim, Michael P. Hart, Alice S. Chen-Plotkin, Brian S. Johnson, Xiaodong Fang, Maria Armakola, Felix Geser, Robert Greene, Min Min Lu, Arun Padmanabhan, Dana Clay-Falcone, Leo McCluskey, Lauren Elman, Denise Juhr, Peter J. Gruber, Udo Rüb, Georg Auburger, John Q. Trojanowski, Virginia M.-Y. Lee, Vivianna M. Van Deerlin, Nancy M. Bonini and Aaron D. Gitler

Heterochromatin silencing of p53 target genes by a small viral protein pp. 1076-1081

Conrado Soria, Fanny E. Estermann, Kristen C. Espantman and Clodagh C. O’Shea

Direct formation of supermassive black holes via multi-scale gas inflows in galaxy mergers pp. 1082-1084

L. Mayer, S. Kazantzidis, A. Escala and S. Callegari

Formation of asteroid pairs by rotational fission pp. 1085-1088

P. Pravec, D. Vokrouhlický, D. Polishook, D. J. Scheeres, A. W. Harris, A. Galád, O. Vaduvescu, F. Pozo, A. Barr, P. Longa, F. Vachier, F. Colas, D. P. Pray, J. Pollock, D. Reichart, K. Ivarsen, J. Haislip, A. LaCluyze, P. Kušnirák, T. Henych, F. Marchis, B. Macomber, S. A. Jacobson, Yu. N. Krugly, A. V. Sergeev and A. Leroy

Coherent measurements of high-order electronic correlations in quantum wells pp. 1089-1092

Daniel B. Turner and Keith A. Nelson

Upper-ocean-to-atmosphere radiocarbon offsets imply fast deglacial carbon dioxide release pp. 1093-1097

Kathryn A. Rose, Elisabeth L. Sikes, Thomas P. Guilderson, Phil Shane, Tessa M. Hill, Rainer Zahn and Howard J. Spero

Global patterns and predictors of marine biodiversity across taxa pp. 1098-1101

Derek P. Tittensor, Camilo Mora, Walter Jetz, Heike K. Lotze, Daniel Ricard, Edward Vanden Berghe and Boris Worm

Statistical inference for noisy nonlinear ecological dynamic systems pp. 1102-1104

Simon N. Wood

A novel pathway regulates memory and plasticity via SIRT1 and miR-134 pp. 1105-1109

Jun Gao, Wen-Yuan Wang, Ying-Wei Mao, Johannes Gräff, Ji-Song Guan, Ling Pan, Gloria Mak, Dohoon Kim, Susan C. Su and Li-Huei Tsai

Rb regulates fate choice and lineage commitment in vivo pp. 1110-1114

Eliezer Calo, Jose A. Quintero-Estades, Paul S. Danielian, Simona Nedelcu, Seth D. Berman and Jacqueline A. Lees

IκBβ acts to inhibit and activate gene expression during the inflammatory response pp. 1115-1119

Ping Rao, Mathew S. Hayden, Meixiao Long, Martin L. Scott, A. Philip West, Dekai Zhang, Andrea Oeckinghaus, Candace Lynch, Alexander Hoffmann, David Baltimore and Sankar Ghosh

A ribosome-associating factor chaperones tail-anchored membrane proteins pp. 1120-1124

Malaiyalam Mariappan, Xingzhe Li, Sandra Stefanovic, Ajay Sharma, Agnieszka Mateja, Robert J. Keenan and Ramanujan S. Hegde

NRMT is an α-N-methyltransferase that methylates RCC1 and retinoblastoma protein pp. 1125-1128

Christine E. Schaner Tooley, Janusz J. Petkowski, Tara L. Muratore-Schroeder, Jeremy L. Balsbaugh, Jeffrey Shabanowitz, Michal Sabat, Wladek Minor, Donald F. Hunt and Ian G. Macara

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification pp. 1129-1133

Shinsuke Ito, Ana C. D’Alessio, Olena V. Taranova, Kwonho Hong, Lawrence C. Sowers and Yi Zhang

Erratum: The giant bite of a new raptorial sperm whale from the Miocene epoch of Peru pp. 1134-1134

Olivier Lambert, Giovanni Bianucci, Klaas Post, Christian de Muizon, Rodolfo Salas-Gismondi, Mario Urbina and Jelle Reumer

Erratum: Fighting the monster pp. 1134-1134

Amy Maxmen

Erratum: Temperature-controlled organic carbon mineralization in lake sediments pp. 1134-1134

Cristian Gudasz, David Bastviken, Kristin Steger, Katrin Premke, Sebastian Sobek and Lars J. Tranvik

Erratum: Detection of functional haematopoietic stem cell niche using real-time imaging pp. 1134-1134

Yucai Xie, Tong Yin, Winfried Wiegraebe, Xi C. He, Diana Miller, Danny Stark, Katherine Perko, Richard Alexander, Joel Schwartz, Justin Grindley, Jungeun Park, Jeff Haug, Joshua Wunderlich, Hua Li, Simon Zhang, Teri Johnson, Ricardo A. Feldman and Linheng Li

Taking a long, hard look pp. 1137-1138

Monya Baker

A dual dilemma pp. 1144-1145

Karen Kaplan

Negotiating for two pp. 1145-1146

Karen Kaplan

Me am Petri pp. 1148-1148

Martin Hayes

2010, volume 466, articles 7309

Laryngeally echolocating bats pp. E6-E6

Ulrich Wittrock

Veselka et al. reply pp. E7-E7

Nina Veselka, David D. McErlain, David W. Holdsworth, Judith L. Eger, Rethy K. Chhem, Matthew J. Mason, Kirsty L. Brain, Paul A. Faure and M. Brock Fenton

Inferring echolocation in ancient bats pp. E8-E8

Nancy B. Simmons, Kevin L. Seymour, Jörg Habersetzer and Gregg F. Gunnell

Veselka et al. reply pp. E9-E9

Nina Veselka, David D. McErlain, David W. Holdsworth, Judith L. Eger, Rethy K. Chhem, Matthew J. Mason, Kirsty L. Brain, Paul A. Faure and M. Brock Fenton

Journal club pp. 905-905

Gerry Melino

Harvard probe kept under wraps pp. 908-909

Heidi Ledford

FDA challenges stem-cell clinic pp. 909-909

David Cyranoski

US survey sets cosmic priorities pp. 910-910

Adam Mann

Science panel gives hope in river-pollution dispute pp. 911-911

Anna Petherick

Jet reveals atmosphere's secrets pp. 912-912

Jeff Tollefson

E-mails spark ethics row pp. 913-913

Rex Dalton

Physiology: The bones of contention pp. 914-915

Alla Katsnelson

Biotechnology: Crossing the barrier pp. 916-918

Brian Vastag

World view: Leaders wanted pp. 919-919

Colin Macilwain

Mitigate food loss to feed more people right now pp. 920-920

Trevor Nicholls

Culturing practices can make roots more robust too pp. 920-920

Norman Uphoff

Reduce soil damage for more sustainable crop production pp. 920-920

Jeff Tullberg

Monitoring systems outdated and protectionist pp. 920-920

Kamaljit S. Bawa

Track social and economic impacts of food production pp. 920-920

Don Gunasekera and John Finnigan

Long view of the Human Genome Project pp. 921-922

Jan Witkowski

In Retrospect: Science — The Endless Frontier pp. 922-923

Roger Pielke

Books in brief pp. 923-923

Joanne Baker

A missing sink for radicals pp. 925-926

Jos Lelieveld

How plants avoid incest pp. 926-927

Daphne Goring and Emily Indriolo

Waves on Orion's shores pp. 928-929

John Bally

Blocking ubiquitin transfer pp. 929-930

April Rose and Christian Schlieker

Oh sibling, who art thou? pp. 930-931

Andrew Cockburn

Double trouble at Tonga pp. 931-932

Kenji Satake

Stephen Henry Schneider (1945–2010) pp. 933-933

Michael D. Mastrandrea

Type IIA topoisomerase inhibition by a new class of antibacterial agents pp. 935-940

Benjamin D. Bax, Pan F. Chan, Drake S. Eggleston, Andrew Fosberry, Daniel R. Gentry, Fabrice Gorrec, Ilaria Giordano, Michael M. Hann, Alan Hennessy, Martin Hibbs, Jianzhong Huang, Emma Jones, Jo Jones, Kristin Koretke Brown, Ceri J. Lewis, Earl W. May, Martin R. Saunders, Onkar Singh, Claus E. Spitzfaden, Carol Shen, Anthony Shillings, Andrew J. Theobald, Alexandre Wohlkonig, Neil D. Pearson and Michael N. Gwynn

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1 pp. 941-946

Shinichiro Nakada, Ikue Tai, Stephanie Panier, Abdallah Al-Hakim, Shun-ichiro Iemura, Yu-Chi Juang, Lara O’Donnell, Ayako Kumakubo, Meagan Munro, Frank Sicheri, Anne-Claude Gingras, Tohru Natsume, Toshio Suda and Daniel Durocher

Waves on the surface of the Orion molecular cloud pp. 947-949

Olivier Berné, Núria Marcelino and José Cernicharo

Enhancement of superconductivity by pressure-driven competition in electronic order pp. 950-953

Xiao-Jia Chen, Viktor V. Struzhkin, Yong Yu, Alexander F. Goncharov, Cheng-Tian Lin, Ho-kwang Mao and Russell J. Hemley

A strong ferroelectric ferromagnet created by means of spin–lattice coupling pp. 954-958

June Hyuk Lee, Lei Fang, Eftihia Vlahos, Xianglin Ke, Young Woo Jung, Lena Fitting Kourkoutis, Jong-Woo Kim, Philip J. Ryan, Tassilo Heeg, Martin Roeckerath, Veronica Goian, Margitta Bernhagen, Reinhard Uecker, P. Chris Hammel, Karin M. Rabe, Stanislav Kamba, Jürgen Schubert, John W. Freeland, David A. Muller, Craig J. Fennie, Peter Schiffer, Venkatraman Gopalan, Ezekiel Johnston-Halperin and Darrell G. Schlom

Near-simultaneous great earthquakes at Tongan megathrust and outer rise in September 2009 pp. 959-963

J. Beavan, X. Wang, C. Holden, K. Wilson, W. Power, G. Prasetya, M. Bevis and R. Kautoke

The 2009 Samoa–Tonga great earthquake triggered doublet pp. 964-968

Thorne Lay, Charles J. Ammon, Hiroo Kanamori, Luis Rivera, Keith D. Koper and Alexander R. Hutko

Promiscuity and the evolutionary transition to complex societies pp. 969-972

Charlie K. Cornwallis, Stuart A. West, Katie E. Davis and Ashleigh S. Griffin

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis pp. 973-977

Matthew P. R. Berry, Christine M. Graham, Finlay W. McNab, Zhaohui Xu, Susannah A. A. Bloch, Tolu Oni, Katalin A. Wilkinson, Romain Banchereau, Jason Skinner, Robert J. Wilkinson, Charles Quinn, Derek Blankenship, Ranju Dhawan, John J. Cush, Asuncion Mejias, Octavio Ramilo, Onn M. Kon, Virginia Pascual, Jacques Banchereau, Damien Chaussabel and Anne O’Garra

Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells pp. 978-982

Paola Bonfanti, Stéphanie Claudinot, Alessandro W. Amici, Alison Farley, C. Clare Blackburn and Yann Barrandon

Trans-acting small RNA determines dominance relationships in Brassica self-incompatibility pp. 983-986

Yoshiaki Tarutani, Hiroshi Shiba, Megumi Iwano, Tomohiro Kakizaki, Go Suzuki, Masao Watanabe, Akira Isogai and Seiji Takayama

Regulation of heterochromatic DNA replication by histone H3 lysine 27 methyltransferases pp. 987-991

Yannick Jacob, Hume Stroud, Chantal LeBlanc, Suhua Feng, Luting Zhuo, Elena Caro, Christiane Hassel, Crisanto Gutierrez, Scott D. Michaels and Steven E. Jacobsen

A mechanically stabilized receptor–ligand flex-bond important in the vasculature pp. 992-995

Jongseong Kim, Cheng-Zhong Zhang, Xiaohui Zhang and Timothy A. Springer

Structure of the torque ring of the flagellar motor and the molecular basis for rotational switching pp. 996-1000

Lawrence K. Lee, Michael A. Ginsburg, Claudia Crovace, Mhairi Donohoe and Daniela Stock

Crystal structure of the α6β6 holoenzyme of propionyl-coenzyme A carboxylase pp. 1001-1005

Christine S. Huang, Kianoush Sadre-Bazzaz, Yang Shen, Binbin Deng, Z. Hong Zhou and Liang Tong

Erratum: An allosteric mechanism of Rho-dependent transcription termination pp. 1006-1006

Vitaly Epshtein, Dipak Dutta, Joseph Wade and Evgeny Nudler

Erratum: Grassroots initiatives pp. 1006-1006

Amy Maxmen

Erratum: Quantum oscillations in a molecular magnet pp. 1006-1006

S. Bertaina, S. Gambarelli, T. Mitra, B. Tsukerblat, A. Müller and B. Barbara

Erratum: Above-room-temperature ferroelectricity in a single-component molecular crystal pp. 1006-1006

Sachio Horiuchi, Yusuke Tokunaga, Gianluca Giovannetti, Silvia Picozzi, Hirotake Itoh, Ryo Shimano, Reiji Kumai and Yoshinori Tokura

Search tool for career data launched pp. 1009-1009

Gene Russo

Stefania Mondello pp. 1009-1009

Virginia Gewin

Weighing the options pp. 1010-1011

Tamar Nordenberg

Stay special pp. 1014-1014

Susan Lanigan

2010, volume 466, articles 7308

The prion protein as a receptor for amyloid-β pp. E3-E4

Helmut W. Kessels, Louis N. Nguyen, Sadegh Nabavi and Roberto Malinow

Laurén et al. reply pp. E4-E5

Juha Laurén, David A. Gimbel, Haakon B. Nygaard, John W. Gilbert and Stephen M. Strittmatter

Journal club pp. 799-799

Ian Howat

Upbeat oil report questioned pp. 802-802

Mark Schrope

Power struggle hits Swedish institute pp. 803-803

Alison Abbott

France digs deep for nuclear waste pp. 804-805

Declan Butler

Mountain mining damages streams pp. 806-806

Natasha Gilbert

Supercomputing for the birds pp. 807-807

Emma Marris

Francis Collins: One year at the helm pp. 808-810

Meredith Wadman

Oceanography: Dead in the water pp. 812-814

Virginia Gewin

Concerns regarding sinking of South Korean warship pp. 815-815

Kwang Sup Kim

Problems in Turkish science run deeper than petty disputes pp. 815-815

Ferhat Kaya

Press release and media distort complex message pp. 815-815

Víctor H. Marín, Luisa E. Delgado and Antonio Tironi

Difference between interim and final acid-rain reports pp. 815-815

Naomi Oreskes and Erik M. Conway

Which way for genetic-test regulation? Leave test interpretation to specialists pp. 816-817

Arthur L. Beaudet

Which way for genetic-test regulation? Assign regulation appropriate to the level of risk pp. 817-818

Gail Javitt

The makings of great leaders pp. 819-820

Michael Bond

Palestinians and Israelis talk water pp. 820-820

Haim Watzman

A signal take on speech pp. 821-822

Michael S. Lewicki

Relict mantle from Earth's birth pp. 822-823

David Graham

A mine of imprinted genes pp. 823-824

Eric B. Keverne

Sudden larch death pp. 824-825

Clive Brasier and Joan Webber

The benefit of fractal dirt pp. 825-826

Jan Zaanen

Genes and the anxious brain pp. 827-828

Andreas Meyer-Lindenberg

Australopithecine butchers pp. 828-828

David R. Braun

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche pp. 829-834

Simón Méndez-Ferrer, Tatyana V. Michurina, Francesca Ferraro, Amin R. Mazloom, Ben D. MacArthur, Sergio A. Lira, David T. Scadden, Avi Ma’ayan, Grigori N. Enikolopov and Paul S. Frenette

Mammalian microRNAs predominantly act to decrease target mRNA levels pp. 835-840

Huili Guo, Nicholas T. Ingolia, Jonathan S. Weissman and David P. Bartel

Scale-free structural organization of oxygen interstitials in La2CuO4+y pp. 841-844

Michela Fratini, Nicola Poccia, Alessandro Ricci, Gaetano Campi, Manfred Burghammer, Gabriel Aeppli and Antonio Bianconi

Nanoscale scanning probe ferromagnetic resonance imaging using localized modes pp. 845-848

Inhee Lee, Yuri Obukhov, Gang Xiang, Adam Hauser, Fengyuan Yang, Palash Banerjee, Denis V. Pelekhov and P. Chris Hammel

Precipitation-generated oscillations in open cellular cloud fields pp. 849-852

Graham Feingold, Ilan Koren, Hailong Wang, Huiwen Xue and Wm. Alan Brewer

Evidence for the survival of the oldest terrestrial mantle reservoir pp. 853-856

Matthew G. Jackson, Richard W. Carlson, Mark D. Kurz, Pamela D. Kempton, Don Francis and Jerzy Blusztajn

Evidence for stone-tool-assisted consumption of animal tissues before 3.39 million years ago at Dikika, Ethiopia pp. 857-860

Shannon P. McPherron, Zeresenay Alemseged, Curtis W. Marean, Jonathan G. Wynn, Denné Reed, Denis Geraads, René Bobe and Hamdallah A. Béarat

Social learning promotes institutions for governing the commons pp. 861-863

Karl Sigmund, Hannelore De Silva, Arne Traulsen and Christoph Hauert

Amygdalar and hippocampal substrates of anxious temperament differ in their heritability pp. 864-868

Jonathan A. Oler, Andrew S. Fox, Steven E. Shelton, Jeffrey Rogers, Thomas D. Dyer, Richard J. Davidson, Wendy Shelledy, Terrence R. Oakes, John Blangero and Ned H. Kalin

Diverse somatic mutation patterns and pathway alterations in human cancers pp. 869-873

Zhengyan Kan, Bijay S. Jaiswal, Jeremy Stinson, Vasantharajan Janakiraman, Deepali Bhatt, Howard M. Stern, Peng Yue, Peter M. Haverty, Richard Bourgon, Jianbiao Zheng, Martin Moorhead, Subhra Chaudhuri, Lynn P. Tomsho, Brock A. Peters, Kanan Pujara, Shaun Cordes, David P. Davis, Victoria E. H. Carlton, Wenlin Yuan, Li Li, Weiru Wang, Charles Eigenbrot, Joshua S. Kaminker, David A. Eberhard, Paul Waring, Stephan C. Schuster, Zora Modrusan, Zemin Zhang, David Stokoe, Frederic J. de Sauvage, Malek Faham and Somasekar Seshagiri

Wnt11 patterns a myocardial electrical gradient through regulation of the L-type Ca2+ channel pp. 874-878

Daniela Panáková, Andreas A. Werdich and Calum A. MacRae

Microtubule nucleating γ-TuSC assembles structures with 13-fold microtubule-like symmetry pp. 879-882

Justin M. Kollman, Jessica K. Polka, Alex Zelter, Trisha N. Davis and David A. Agard

Structure of the LexA–DNA complex and implications for SOS box measurement pp. 883-886

Adrianna P. P. Zhang, Ying Z. Pigli and Phoebe A. Rice

Dynamics and mechanism of repair of ultraviolet-induced (6–4) photoproduct by photolyase pp. 887-890

Jiang Li, Zheyun Liu, Chuang Tan, Xunmin Guo, Lijuan Wang, Aziz Sancar and Dongping Zhong

Jeffrey Koplan pp. 892-892

Karen Kaplan

Scientific career renewal pp. 893-893

Peter Fiske

Killing time pp. 896-896

John Gilbey

2010, volume 466, articles 7307

Fleeting but sweet pp. 1-1

Marwan Azar

Journal club pp. 669-669

Dov Sax

Demand for malaria drug soars pp. 672-673

Richard Van Noorden

Sponge genome goes deep pp. 673-673

Adam Mann

UK embryo agency faces the axe pp. 674-674

Daniel Cressey

Salamander's egg surprise pp. 675-675

Anna Petherick

'Tough' chief to defend MRC pp. 675-675

Daniel Cressey

Drug safety crackdown revs up pp. 677-677

Heidi Ledford

US report pins down future biosecurity pp. 678-678

Meredith Wadman

Deepwater Horizon: A scientist at the centre of the spill pp. 680-684

Mark Schrope

Citizen science: People power pp. 685-687

Eric Hand

World view: Not by experts alone pp. 688-688

Daniel Sarewitz

UK coalition's funding plan accelerates trends Labour started pp. 689-689

William Cullerne Bown

The long story of how the boson got only Higgs's name pp. 689-689

Ian Sample

Harnessing telecoms cables for science pp. 690-691

Yuzhu You

Overcoming agony pp. 692-693

Lucy Odling-Smee

An embellished tale of Pluto's discovery pp. 693-694

Caleb Scharf

Behind the Mona Lisa's smile pp. 694-694

Philip Ball

Serious fun with computer games pp. 695-695

Aleks Krotoski

An inner core slip-sliding away pp. 697-698

Michael I. Bergman

Close relatives are bad news pp. 698-699

Owen T. Lewis

Genes, viruses and microbes pp. 699-700

Alison Simmons

Attosecond prints of electrons pp. 701-702

Olga Smirnova

From fin to forelimb pp. 701-701

Katie Ridd

Malaria parasite stands out pp. 702-703

Hagai Ginsburg

Variations in blood lipids pp. 703-704

Alan R. Shuldiner and Toni I. Pollin

Cation o' nine tails pp. 704-705

Polly L. Arnold

Harry Whittington (1916–2010) pp. 706-706

Derek E. G. Briggs

Biological, clinical and population relevance of 95 loci for blood lipids pp. 707-713

Tanya M. Teslovich, Kiran Musunuru, Albert V. Smith, Andrew C. Edmondson, Ioannis M. Stylianou, Masahiro Koseki, James P. Pirruccello, Samuli Ripatti, Daniel I. Chasman, Cristen J. Willer, Christopher T. Johansen, Sigrid W. Fouchier, Aaron Isaacs, Gina M. Peloso, Maja Barbalic, Sally L. Ricketts, Joshua C. Bis, Yurii S. Aulchenko, Gudmar Thorleifsson, Mary F. Feitosa, John Chambers, Marju Orho-Melander, Olle Melander, Toby Johnson, Xiaohui Li, Xiuqing Guo, Mingyao Li, Yoon Shin Cho, Min Jin Go, Young Jin Kim, Jong-Young Lee, Taesung Park, Kyunga Kim, Xueling Sim, Rick Twee-Hee Ong, Damien C. Croteau-Chonka, Leslie A. Lange, Joshua D. Smith, Kijoung Song, Jing Hua Zhao, Xin Yuan, Jian’an Luan, Claudia Lamina, Andreas Ziegler, Weihua Zhang, Robert Y. L. Zee, Alan F. Wright, Jacqueline C. M. Witteman, James F. Wilson, Gonneke Willemsen, H.-Erich Wichmann, John B. Whitfield, Dawn M. Waterworth, Nicholas J. Wareham, Gérard Waeber, Peter Vollenweider, Benjamin F. Voight, Veronique Vitart, Andre G. Uitterlinden, Manuela Uda, Jaakko Tuomilehto, John R. Thompson, Toshiko Tanaka, Ida Surakka, Heather M. Stringham, Tim D. Spector, Nicole Soranzo, Johannes H. Smit, Juha Sinisalo, Kaisa Silander, Eric J. G. Sijbrands, Angelo Scuteri, James Scott, David Schlessinger, Serena Sanna, Veikko Salomaa, Juha Saharinen, Chiara Sabatti, Aimo Ruokonen, Igor Rudan, Lynda M. Rose, Robert Roberts, Mark Rieder, Bruce M. Psaty, Peter P. Pramstaller, Irene Pichler, Markus Perola, Brenda W. J. H. Penninx, Nancy L. Pedersen, Cristian Pattaro, Alex N. Parker, Guillaume Pare, Ben A. Oostra, Christopher J. O’Donnell, Markku S. Nieminen, Deborah A. Nickerson, Grant W. Montgomery, Thomas Meitinger, Ruth McPherson, Mark I. McCarthy, Wendy McArdle, David Masson, Nicholas G. Martin, Fabio Marroni, Massimo Mangino, Patrik K. E. Magnusson, Gavin Lucas, Robert Luben, Ruth J. F. Loos, Marja-Liisa Lokki, Guillaume Lettre, Claudia Langenberg, Lenore J. Launer, Edward G. Lakatta, Reijo Laaksonen, Kirsten O. Kyvik, Florian Kronenberg, Inke R. König, Kay-Tee Khaw, Jaakko Kaprio, Lee M. Kaplan, Åsa Johansson, Marjo-Riitta Jarvelin, A. Cecile J. W. Janssens, Erik Ingelsson, Wilmar Igl, G. Kees Hovingh, Jouke-Jan Hottenga, Albert Hofman, Andrew A. Hicks, Christian Hengstenberg, Iris M. Heid, Caroline Hayward, Aki S. Havulinna, Nicholas D. Hastie, Tamara B. Harris, Talin Haritunians, Alistair S. Hall, Ulf Gyllensten, Candace Guiducci, Leif C. Groop, Elena Gonzalez, Christian Gieger, Nelson B. Freimer, Luigi Ferrucci, Jeanette Erdmann, Paul Elliott, Kenechi G. Ejebe, Angela Döring, Anna F. Dominiczak, Serkalem Demissie, Panagiotis Deloukas, Eco J. C. de Geus, Ulf de Faire, Gabriel Crawford, Francis S. Collins, Yii- der I. Chen, Mark J. Caulfield, Harry Campbell, Noel P. Burtt, Lori L. Bonnycastle, Dorret I. Boomsma, S. Matthijs Boekholdt, Richard N. Bergman, Inês Barroso, Stefania Bandinelli, Christie M. Ballantyne, Themistocles L. Assimes, Thomas Quertermous, David Altshuler, Mark Seielstad, Tien Y. Wong, E-Shyong Tai, Alan B. Feranil, Christopher W. Kuzawa, Linda S. Adair, Herman A. Taylor, Ingrid B. Borecki, Stacey B. Gabriel, James G. Wilson, Hilma Holm, Unnur Thorsteinsdottir, Vilmundur Gudnason, Ronald M. Krauss, Karen L. Mohlke, Jose M. Ordovas, Patricia B. Munroe, Jaspal S. Kooner, Alan R. Tall, Robert A. Hegele, John J.P. Kastelein, Eric E. Schadt, Jerome I. Rotter, Eric Boerwinkle, David P. Strachan, Vincent Mooser, Kari Stefansson, Muredach P. Reilly, Nilesh J Samani, Heribert Schunkert, L. Adrienne Cupples, Manjinder S. Sandhu, Paul M Ridker, Daniel J. Rader, Cornelia M. van Duijn, Leena Peltonen, Gonçalo R. Abecasis, Michael Boehnke and Sekar Kathiresan

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus pp. 714-719

Kiran Musunuru, Alanna Strong, Maria Frank-Kamenetsky, Noemi E. Lee, Tim Ahfeldt, Katherine V. Sachs, Xiaoyu Li, Hui Li, Nicolas Kuperwasser, Vera M. Ruda, James P. Pirruccello, Brian Muchmore, Ludmila Prokunina-Olsson, Jennifer L. Hall, Eric E. Schadt, Carlos R. Morales, Sissel Lund-Katz, Michael C. Phillips, Jamie Wong, William Cantley, Timothy Racie, Kenechi G. Ejebe, Marju Orho-Melander, Olle Melander, Victor Koteliansky, Kevin Fitzgerald, Ronald M. Krauss, Chad A. Cowan, Sekar Kathiresan and Daniel J. Rader

The Amphimedon queenslandica genome and the evolution of animal complexity pp. 720-726

Mansi Srivastava, Oleg Simakov, Jarrod Chapman, Bryony Fahey, Marie E. A. Gauthier, Therese Mitros, Gemma S. Richards, Cecilia Conaco, Michael Dacre, Uffe Hellsten, Claire Larroux, Nicholas H. Putnam, Mario Stanke, Maja Adamska, Aaron Darling, Sandie M. Degnan, Todd H. Oakley, David C. Plachetzki, Yufeng Zhai, Marcin Adamski, Andrew Calcino, Scott F. Cummins, David M. Goodstein, Christina Harris, Daniel J. Jackson, Sally P. Leys, Shengqiang Shu, Ben J. Woodcroft, Michel Vervoort, Kenneth S. Kosik, Gerard Manning, Bernard M. Degnan and Daniel S. Rokhsar

A ground-layer adaptive optics system with multiple laser guide stars pp. 727-729

M. Hart, N. M. Milton, C. Baranec, K. Powell, T. Stalcup, D. McCarthy, C. Kulesa and E. Bendek

Quantum entanglement between an optical photon and a solid-state spin qubit pp. 730-734

E. Togan, Y. Chu, A. S. Trifonov, L. Jiang, J. Maze, L. Childress, M. V. G. Dutt, A. S. Sørensen, P. R. Hemmer, A. S. Zibrov and M. D. Lukin

Loss-free and active optical negative-index metamaterials pp. 735-738

Shumin Xiao, Vladimir P. Drachev, Alexander V. Kildishev, Xingjie Ni, Uday K. Chettiar, Hsiao-Kuan Yuan and Vladimir M. Shalaev

Real-time observation of valence electron motion pp. 739-743

Eleftherios Goulielmakis, Zhi-Heng Loh, Adrian Wirth, Robin Santra, Nina Rohringer, Vladislav S. Yakovlev, Sergey Zherebtsov, Thomas Pfeifer, Abdallah M. Azzeer, Matthias F. Kling, Stephen R. Leone and Ferenc Krausz

Melting-induced stratification above the Earth’s inner core due to convective translation pp. 744-747

Thierry Alboussière, Renaud Deguen and Mickaël Melzani

The evolution of mammal-like crocodyliforms in the Cretaceous Period of Gondwana pp. 748-751

Patrick M. O’Connor, Joseph J. W. Sertich, Nancy J. Stevens, Eric M. Roberts, Michael D. Gottfried, Tobin L. Hieronymus, Zubair A. Jinnah, Ryan Ridgely, Sifa E. Ngasala and Jesuit Temba

Negative plant–soil feedback predicts tree-species relative abundance in a tropical forest pp. 752-755

Scott A. Mangan, Stefan A. Schnitzer, Edward A. Herre, Keenan M. L. Mack, Mariana C. Valencia, Evelyn I. Sanchez and James D. Bever

Predicting protein structures with a multiplayer online game pp. 756-760

Seth Cooper, Firas Khatib, Adrien Treuille, Janos Barbero, Jeehyung Lee, Michael Beenen, Andrew Leaver-Fay, David Baker, Zoran Popović and Foldit Players

Link communities reveal multiscale complexity in networks pp. 761-764

Yong-Yeol Ahn, James P. Bagrow and Sune Lehmann

Regulation of myeloid leukaemia by the cell-fate determinant Musashi pp. 765-768

Takahiro Ito, Hyog Young Kwon, Bryan Zimdahl, Kendra L. Congdon, Jordan Blum, William E. Lento, Chen Zhao, Anand Lagoo, Gareth Gerrard, Letizia Foroni, John Goldman, Harriet Goh, Soo-Hyun Kim, Dong-Wook Kim, Charles Chuah, Vivian G. Oehler, Jerald P. Radich, Craig T. Jordan and Tannishtha Reya

Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells pp. 769-773

Jose L. Garcia-Perez, Maria Morell, Joshua O. Scheys, Deanna A. Kulpa, Santiago Morell, Christoph C. Carter, Gary D. Hammer, Kathleen L. Collins, K. Sue O’Shea, Pablo Menendez and John V. Moran

Branched tricarboxylic acid metabolism in Plasmodium falciparum pp. 774-778

Kellen L. Olszewski, Michael W. Mather, Joanne M. Morrisey, Benjamin A. Garcia, Akhil B. Vaidya, Joshua D. Rabinowitz and Manuel Llinás

Microbial metalloproteomes are largely uncharacterized pp. 779-782

Aleksandar Cvetkovic, Angeli Lal Menon, Michael P. Thorgersen, Joseph W. Scott, Farris L. Poole, Francis E. Jenney, W. Andrew Lancaster, Jeremy L. Praissman, Saratchandra Shanmukh, Brian J. Vaccaro, Sunia A. Trauger, Ewa Kalisiak, Junefredo V. Apon, Gary Siuzdak, Steven M. Yannone, John A. Tainer and Michael W. W. Adams

Researchers on a mission pp. 784-786

Emma Marris

The silver bullet and the golden goose pp. 788-788

Norman Spinrad

2010, volume 466, articles 7306

Discipline beyond disciplines pp. 1-1

Fabio Paglieri

Journal club pp. 535-535

Kenji Doya

Freedom of spill research threatened pp. 538-538

Amanda Mascarelli

Therapeutic HIV vaccines show promise pp. 539-539

Alison Abbott

A closer look at cosmic impacts pp. 540-540

Roberta Kwok

Retraction recommended for enzyme-chip paper pp. 540-541

Alison Abbott

US seeks solar flair for fuels pp. 541-541

Jeff Tollefson

Fears over Europe's GM crop plan pp. 542-542

Andrea Chipman

US charges scientist with economic espionage pp. 542-543

Sharon Weinberger

Protein mapping gains a human focus pp. 544-544

Heidi Ledford

Food: Inside the hothouses of industry pp. 548-551

Natasha Gilbert

Food: An underground revolution pp. 552-553

Virginia Gewin

Food: The global farm pp. 554-556

Jeff Tollefson

Monitoring the world's agriculture pp. 558-560

Jeffrey Sachs, Roseline Remans, Sean Smukler, Leigh Winowiecki, Sandy J. Andelman, Kenneth G. Cassman, David Castle, Ruth DeFries, Glenn Denning, Jessica Fanzo, Louise E. Jackson, Rik Leemans, Johannes Lehmann, Jeffrey C. Milder, Shahid Naeem, Generose Nziguheba, Cheryl A. Palm, Prabhu L. Pingali, John P. Reganold, Daniel D. Richter, Sara J. Scherr, Jason Sircely, Clare Sullivan, Thomas P. Tomich and Pedro A. Sanchez

Regulation must be revolutionized pp. 561-561

Ingo Potrykus

European Commission clarifies the rules for research audits pp. 562-562

Máire Geoghegan-Quinn

Vacation reading pp. 563-566

Steven Shapin, W. F. Bynum, Michael Shermer, Nicky Clayton, Serge Daan, Hans von Storch, Li Gong, David Orr, Daniel Levitin, Rodrigo Quian Quiroga, Candis Callison, Jennifer Rohn, Pat Shipman, Jessica Hellmann, Abdallah Daar and Vaclav Smil

An eye to treating blindness pp. 567-568

Elena Ezhkova and Elaine Fuchs

Climate and intraplate shocks pp. 568-569

Mark D. Zoback

Century of phytoplankton change pp. 569-571

David A. Siegel and Bryan A. Franz

Tick, tock, a β-cell clock pp. 571-572

Katja A. Lamia and Ronald M. Evans

Bringing the noise pp. 572-573

Chetan Nayak

The four hundred years of planetary science since Galileo and Kepler pp. 575-584

Joseph A. Burns

Observation of neutral modes in the fractional quantum Hall regime pp. 585-590

Aveek Bid, N. Ofek, H. Inoue, M. Heiblum, C. L. Kane, V. Umansky and D. Mahalu

Global phytoplankton decline over the past century pp. 591-596

Daniel G. Boyce, Marlon R. Lewis and Boris Worm

Pinning quantum phase transition for a Luttinger liquid of strongly interacting bosons pp. 597-600

Elmar Haller, Russell Hart, Manfred J. Mark, Johann G. Danzl, Lukas Reichsöllner, Mattias Gustavsson, Marcello Dalmonte, Guido Pupillo and Hanns-Christoph Nägerl

Direct generation of photon triplets using cascaded photon-pair sources pp. 601-603

Hannes Hübel, Deny R. Hamel, Alessandro Fedrizzi, Sven Ramelow, Kevin J. Resch and Thomas Jennewein

Following a chemical reaction using high-harmonic interferometry pp. 604-607

H. J. Wörner, J. B. Bertrand, D. V. Kartashov, P. B. Corkum and D. M. Villeneuve

Triggering of New Madrid seismicity by late-Pleistocene erosion pp. 608-611

E. Calais, A. M. Freed, R. Van Arsdale and S. Stein

Convergent evolution of chicken Z and human X chromosomes by expansion and gene acquisition pp. 612-616

Daniel W. Bellott, Helen Skaletsky, Tatyana Pyntikova, Elaine R. Mardis, Tina Graves, Colin Kremitzki, Laura G. Brown, Steve Rozen, Wesley C. Warren, Richard K. Wilson and David C. Page

Sparse coding and high-order correlations in fine-scale cortical networks pp. 617-621

Ifije E. Ohiorhenuan, Ferenc Mechler, Keith P. Purpura, Anita M. Schmid, Qin Hu and Jonathan D. Victor

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry pp. 622-626

Alexxai V. Kravitz, Benjamin S. Freeze, Philip R. L. Parker, Kenneth Kay, Myo T. Thwin, Karl Deisseroth and Anatol C. Kreitzer

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes pp. 627-631

Biliana Marcheva, Kathryn Moynihan Ramsey, Ethan D. Buhr, Yumiko Kobayashi, Hong Su, Caroline H. Ko, Ganka Ivanova, Chiaki Omura, Shelley Mo, Martha H. Vitaterna, James P. Lopez, Louis H. Philipson, Christopher A. Bradfield, Seth D. Crosby, Lellean JeBailey, Xiaozhong Wang, Joseph S. Takahashi and Joseph Bass

Cross-species genomics matches driver mutations and cell compartments to model ependymoma pp. 632-636

Robert A. Johnson, Karen D. Wright, Helen Poppleton, Kumarasamypet M. Mohankumar, David Finkelstein, Stanley B. Pounds, Vikki Rand, Sarah E. S. Leary, Elsie White, Christopher Eden, Twala Hogg, Paul Northcott, Stephen Mack, Geoffrey Neale, Yong-Dong Wang, Beth Coyle, Jennifer Atkinson, Mariko DeWire, Tanya A. Kranenburg, Yancey Gillespie, Jeffrey C. Allen, Thomas Merchant, Fredrick A. Boop, Robert. A. Sanford, Amar Gajjar, David W. Ellison, Michael D. Taylor, Richard G. Grundy and Richard J. Gilbertson

Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression pp. 637-641

Stephan Gehrke, Yuzuru Imai, Nicholas Sokol and Bingwei Lu

New class of gene-termini-associated human RNAs suggests a novel RNA copying mechanism pp. 642-646

Philipp Kapranov, Fatih Ozsolak, Sang Woo Kim, Sylvain Foissac, Doron Lipson, Chris Hart, Steve Roels, Christelle Borel, Stylianos E. Antonarakis, A. Paula Monaghan, Bino John and Patrice M. Milos

Subnanometre single-molecule localization, registration and distance measurements pp. 647-651

Alexandros Pertsinidis, Yunxiang Zhang and Steven Chu

Erratum: Asymptomatic deer excrete infectious prions in faeces pp. 652-652

Gültekin Tamgüney, Michael W. Miller, Lisa L. Wolfe, Tracey M. Sirochman, David V. Glidden, Christina Palmer, Azucena Lemus, Stephen J. DeArmond and Stanley B. Prusiner

Erratum: NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals pp. 652-652

Peter Duewell, Hajime Kono, Katey J. Rayner, Cherilyn M. Sirois, Gregory Vladimer, Franz G. Bauernfeind, George S. Abela, Luigi Franchi, Gabriel Nuñez, Max Schnurr, Terje Espevik, Egil Lien, Katherine A. Fitzgerald, Kenneth L. Rock, Kathryn J. Moore, Samuel D. Wright, Veit Hornung and Eicke Latz

Backlash against multitasking pp. 655-655

Gene Russo

Enlisting investigators pp. 656-657

Eric Hand

Auntie Merkel pp. 660-660

Deborah Walker

2010, volume 466, articles 7305

Segregation of yeast nuclear pores pp. E1-E1

Anton Khmelinskii, Philipp J. Keller, Holger Lorenz, Elmar Schiebel and Michael Knop

Journal club pp. 417-417

François Fuks

Diabetes drugs offered fresh start pp. 420-420

Heidi Ledford

UK government warned over 'catastrophic' cuts pp. 420-421

Richard Van Noorden

Audit picks a bone with US relics office pp. 422-422

Rex Dalton

Amazon drought raises research doubts pp. 423-423

Jeff Tollefson

Animal rights 'terror' law challenged pp. 424-424

Emma Marris

Report maps perils of warming pp. 425-425

Hannah Hoag

Collider gets yet more exotic 'to-do' list pp. 426-426

Zeeya Merali

Astronomy: Ready for boarding — finally pp. 428-431

Eric Hand

Ecology: A world without mosquitoes pp. 432-434

Janet Fang

They come for the fiction and stay for the science pp. 435-435

James Kakalios

Businesses and biodiversity: they would say that pp. 435-435

Gail Whiteman, Michael Dorsey and Bettina Wittneben

An independent thinker, willing to say what he thought pp. 435-435

Nicolas Nierenberg, Walter R. Tschinkel and Victoria J. Tschinkel

Tie funding to research integrity pp. 436-437

Sandra Titus and Xavier Bosch

Peers nip misconduct in the bud pp. 438-440

Gerald P. Koocher and Patricia Keith-Spiegel

When doubt becomes a weapon pp. 441-442

Brian Wynne

Behind the periodic table pp. 442-442

Philip Ball

New life for antidiabetic drugs pp. 443-444

Riekelt H. Houtkooper and Johan Auwerx

Broad-brush cosmos pp. 444-445

Chris L. Carilli

Fatter marmots on the rise pp. 445-447

Marcel E. Visser

Fluorination made easier pp. 447-448

Tobias Ritter

Hunting the cause of a population crash pp. 448-448

Tamás Székely and William J. Sutherland

Brain's traffic lights pp. 449-449

Paolo Calabresi and Massimiliano Di Filippo

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5 pp. 451-456

Jang Hyun Choi, Alexander S. Banks, Jennifer L. Estall, Shingo Kajimura, Pontus Boström, Dina Laznik, Jorge L. Ruas, Michael J. Chalmers, Theodore M. Kamenecka, Matthias Blüher, Patrick R. Griffin and Bruce M. Spiegelman

Start/stop signals emerge in nigrostriatal circuits during sequence learning pp. 457-462

Xin Jin and Rui M. Costa

An intensity map of hydrogen 21-cm emission at redshift z ≈ 0.8 pp. 463-465

Tzu-Ching Chang, Ue-Li Pen, Kevin Bandura and Jeffrey B. Peterson

Lunar apatite with terrestrial volatile abundances pp. 466-469

Jeremy W. Boyce, Yang Liu, George R. Rossman, Yunbin Guan, John M. Eiler, Edward M. Stolper and Lawrence A. Taylor

Atomically precise bottom-up fabrication of graphene nanoribbons pp. 470-473

Jinming Cai, Pascal Ruffieux, Rached Jaafar, Marco Bieri, Thomas Braun, Stephan Blankenburg, Matthias Muoth, Ari P. Seitsonen, Moussa Saleh, Xinliang Feng, Klaus Müllen and Roman Fasel

Binary nanocrystal superlattice membranes self-assembled at the liquid–air interface pp. 474-477

Angang Dong, Jun Chen, Patrick M. Vora, James M. Kikkawa and Christopher B. Murray

Temperature-controlled organic carbon mineralization in lake sediments pp. 478-481

Cristian Gudasz, David Bastviken, Kristin Steger, Katrin Premke, Sebastian Sobek and Lars J. Tranvik

Coupled dynamics of body mass and population growth in response to environmental change pp. 482-485

Arpat Ozgul, Dylan Z. Childs, Madan K. Oli, Kenneth B. Armitage, Daniel T. Blumstein, Lucretia E. Olson, Shripad Tuljapurkar and Tim Coulson

Allelic variation in a fatty-acyl reductase gene causes divergence in moth sex pheromones pp. 486-489

Jean-Marc Lassance, Astrid T. Groot, Marjorie A. Liénard, Binu Antony, Christin Borgwardt, Fredrik Andersson, Erik Hedenström, David G. Heckel and Christer Löfstedt

Phenotypic robustness conferred by apparently redundant transcriptional enhancers pp. 490-493

Nicolás Frankel, Gregory K. Davis, Diego Vargas, Shu Wang, François Payre and David L. Stern

Co-option of the hormone-signalling module dafachronic acid–DAF-12 in nematode evolution pp. 494-497

Gilberto Bento, Akira Ogawa and Ralf J. Sommer

A new DAF-16 isoform regulates longevity pp. 498-502

Eun-Soo Kwon, Sri Devi Narasimhan, Kelvin Yen and Heidi A. Tissenbaum

Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development pp. 503-507

Hank H. Qi, Madathia Sarkissian, Gang-Qing Hu, Zhibin Wang, Arindam Bhattacharjee, D. Benjamin Gordon, Michelle Gonzales, Fei Lan, Pat P. Ongusaha, Maite Huarte, Nasser K. Yaghi, Huijun Lim, Benjamin A. Garcia, Leonardo Brizuela, Keji Zhao, Thomas M. Roberts and Yang Shi

PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression pp. 508-512

Wen Liu, Bogdan Tanasa, Oksana V. Tyurina, Tian Yuan Zhou, Reto Gassmann, Wei Ting Liu, Kenneth A. Ohgi, Chris Benner, Ivan Garcia-Bassets, Aneel K. Aggarwal, Arshad Desai, Pieter C. Dorrestein, Christopher K. Glass and Michael G. Rosenfeld

LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium pp. 513-516

Jiusheng Yan and Richard W. Aldrich

Kewen Jin pp. 518-518

David Cyranoski

Argentina smooths the path for returnees pp. 519-519

Ana Belluscio

Finding a 'real' job pp. 519-519

Katherine Sixt

Little Dutch boy pp. 522-522

Jeff Crook

2010, volume 466, articles 7304

HIV/AIDS pp. S1-S1

Apoorva Mandavilli

On high alert pp. S2-S3

Emma Marris

Learning from the elite pp. S4-S4

Bijal Trivedi

The primate connection pp. S5-S5

Bijal Trivedi

Dancing with an escape artist pp. S6-S7

Sarah DeWeerdt

Tiny steps towards an HIV vaccine pp. S8-S8

Cassandra Willyard

Joining forces pp. S9-S10

Cassandra Willyard

The outlook for a cure pp. S11-S13

Virginia Hughes

Forgotten lessons pp. S14-S15

Paroma Basu

Developing solutions pp. S16-S17

T. V. Padma

Fighting the monster pp. S18-S19

Amy Maxmen

Grassroots initiatives pp. S20-S20

Amy Maxmen

A call for collaboration pp. S21-S22

Unmesh Kher

Journal club pp. 299-299

Jean Braun

Questions raised over Korean torpedo claims pp. 302-303

David Cyranoski

Japanese monkey deaths puzzle pp. 302-302

David Cyranoski

Start-up model patently flawed pp. 303-303

Zoë Corbyn

The lost legacy of the last great oil spill pp. 304-305

Mark Schrope

Ancient Italian artefacts get the blues pp. 306-306

Alison Abbott

Universities shun Europe's drug initiative pp. 306-307

Natasha Gilbert

China faces up to groundwater crisis pp. 308-308

Jane Qiu

Topological insulators: Star material pp. 310-311

Geoff Brumfiel

Seismology: The secret chatter of giant faults pp. 312-313

Naomi Lubick

World view: ERA of austerity pp. 314-314

Colin Macilwain

Questioning the timeline of H1N1 flu vaccination contracts pp. 315-315

Deborah Cohen and Philip Carter

Gender agenda: positive steps taken in Germany pp. 315-315

Hajo Zeeb, Jacob Spallek and Ingeborg Jahn

Assessing effects of afforestation projects in China pp. 315-315

Xiaohui Yang, Zhiqing Jia and Longjun Ci

Assessing effects of afforestation projects in China: Cao and colleagues reply pp. 315-315

Shixiong Cao, Guosheng Wang and Li Chen

A new strategy for energy innovation pp. 316-317

John Alic, Daniel Sarewitz, Charles Weiss and William Bonvillian

Does diversity always grow? pp. 318-318

Samir Okasha

Silk evolution untangled pp. 319-319

Fritz Vollrath

Books in brief pp. 319-319

Joanne Baker

Q&A: Tod Machover on personal music pp. 320-320

Jascha Hoffman

Is dark energy really a mystery? pp. 321-322

Eugenio Bianchi, Carlo Rovelli and Rocky Kolb

Trade-in to trade-up pp. 322-323

Peter Kareiva

U-turns strictly prohibited pp. 323-324

Marcel Franz

Translocation in slow motion pp. 325-326

Måns Ehrenberg

Proposal with a ring of diamonds pp. 326-327

David A. D. Evans

Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy pp. 329-333

Niels Fischer, Andrey L. Konevega, Wolfgang Wintermeyer, Marina V. Rodnina and Holger Stark

Viruses in the faecal microbiota of monozygotic twins and their mothers pp. 334-338

Alejandro Reyes, Matthew Haynes, Nicole Hanson, Florent E. Angly, Andrew C. Heath, Forest Rohwer and Jeffrey I. Gordon

A hot compact dust disk around a massive young stellar object pp. 339-342

Stefan Kraus, Karl-Heinz Hofmann, Karl M. Menten, Dieter Schertl, Gerd Weigelt, Friedrich Wyrowski, Anthony Meilland, Karine Perraut, Romain Petrov, Sylvie Robbe-Dubois, Peter Schilke and Leonardo Testi

Transmission of topological surface states through surface barriers pp. 343-346

Jungpil Seo, Pedram Roushan, Haim Beidenkopf, Y. S. Hor, R. J. Cava and Ali Yazdani

Intra-unit-cell electronic nematicity of the high-Tc copper-oxide pseudogap states pp. 347-351

M. J. Lawler, K. Fujita, Jhinhwan Lee, A. R. Schmidt, Y. Kohsaka, Chung Koo Kim, H. Eisaki, S. Uchida, J. C. Davis, J. P. Sethna and Eun-Ah Kim

Diamonds sampled by plumes from the core–mantle boundary pp. 352-355

Trond H. Torsvik, Kevin Burke, Bernhard Steinberger, Susan J. Webb and Lewis D. Ashwal

Striations, duration, migration and tidal response in deep tremor pp. 356-359

Satoshi Ide

New Oligocene primate from Saudi Arabia and the divergence of apes and Old World monkeys pp. 360-364

Iyad S. Zalmout, William J. Sanders, Laura M. MacLatchy, Gregg F. Gunnell, Yahya A. Al-Mufarreh, Mohammad A. Ali, Abdul-Azziz H. Nasser, Abdu M. Al-Masari, Salih A. Al-Sobhi, Ayman O. Nadhra, Adel H. Matari, Jeffrey A. Wilson and Philip D. Gingerich

Replacing underperforming protected areas achieves better conservation outcomes pp. 365-367

Richard A. Fuller, Eve McDonald-Madden, Kerrie A. Wilson, Josie Carwardine, Hedley S. Grantham, James E. M. Watson, Carissa J. Klein, David C. Green and Hugh P. Possingham

Functional impact of global rare copy number variation in autism spectrum disorders pp. 368-372

Dalila Pinto, Alistair T. Pagnamenta, Lambertus Klei, Richard Anney, Daniele Merico, Regina Regan, Judith Conroy, Tiago R. Magalhaes, Catarina Correia, Brett S. Abrahams, Joana Almeida, Elena Bacchelli, Gary D. Bader, Anthony J. Bailey, Gillian Baird, Agatino Battaglia, Tom Berney, Nadia Bolshakova, Sven Bölte, Patrick F. Bolton, Thomas Bourgeron, Sean Brennan, Jessica Brian, Susan E. Bryson, Andrew R. Carson, Guillermo Casallo, Jillian Casey, Brian H.Y. Chung, Lynne Cochrane, Christina Corsello, Emily L. Crawford, Andrew Crossett, Cheryl Cytrynbaum, Geraldine Dawson, Maretha de Jonge, Richard Delorme, Irene Drmic, Eftichia Duketis, Frederico Duque, Annette Estes, Penny Farrar, Bridget A. Fernandez, Susan E. Folstein, Eric Fombonne, Christine M. Freitag, John Gilbert, Christopher Gillberg, Joseph T. Glessner, Jeremy Goldberg, Andrew Green, Jonathan Green, Stephen J. Guter, Hakon Hakonarson, Elizabeth A. Heron, Matthew Hill, Richard Holt, Jennifer L. Howe, Gillian Hughes, Vanessa Hus, Roberta Igliozzi, Cecilia Kim, Sabine M. Klauck, Alexander Kolevzon, Olena Korvatska, Vlad Kustanovich, Clara M. Lajonchere, Janine A. Lamb, Magdalena Laskawiec, Marion Leboyer, Ann Le Couteur, Bennett L. Leventhal, Anath C. Lionel, Xiao-Qing Liu, Catherine Lord, Linda Lotspeich, Sabata C. Lund, Elena Maestrini, William Mahoney, Carine Mantoulan, Christian R. Marshall, Helen McConachie, Christopher J. McDougle, Jane McGrath, William M. McMahon, Alison Merikangas, Ohsuke Migita, Nancy J. Minshew, Ghazala K. Mirza, Jeff Munson, Stanley F. Nelson, Carolyn Noakes, Abdul Noor, Gudrun Nygren, Guiomar Oliveira, Katerina Papanikolaou, Jeremy R. Parr, Barbara Parrini, Tara Paton, Andrew Pickles, Marion Pilorge, Joseph Piven, Chris P. Ponting, David J. Posey, Annemarie Poustka, Fritz Poustka, Aparna Prasad, Jiannis Ragoussis, Katy Renshaw, Jessica Rickaby, Wendy Roberts, Kathryn Roeder, Bernadette Roge, Michael L. Rutter, Laura J. Bierut, John P. Rice, Jeff Salt, Katherine Sansom, Daisuke Sato, Ricardo Segurado, Ana F. Sequeira, Lili Senman, Naisha Shah, Val C. Sheffield, Latha Soorya, Inês Sousa, Olaf Stein, Nuala Sykes, Vera Stoppioni, Christina Strawbridge, Raffaella Tancredi, Katherine Tansey, Bhooma Thiruvahindrapduram, Ann P. Thompson, Susanne Thomson, Ana Tryfon, John Tsiantis, Herman Van Engeland, John B. Vincent, Fred Volkmar, Simon Wallace, Kai Wang, Zhouzhi Wang, Thomas H. Wassink, Caleb Webber, Rosanna Weksberg, Kirsty Wing, Kerstin Wittemeyer, Shawn Wood, Jing Wu, Brian L. Yaspan, Danielle Zurawiecki, Lonnie Zwaigenbaum, Joseph D. Buxbaum, Rita M. Cantor, Edwin H. Cook, Hilary Coon, Michael L. Cuccaro, Bernie Devlin, Sean Ennis, Louise Gallagher, Daniel H. Geschwind, Michael Gill, Jonathan L. Haines, Joachim Hallmayer, Judith Miller, Anthony P. Monaco, John I. Nurnberger, Andrew D. Paterson, Margaret A. Pericak-Vance, Gerard D. Schellenberg, Peter Szatmari, Astrid M. Vicente, Veronica J. Vieland, Ellen M. Wijsman, Stephen W. Scherer, James S. Sutcliffe and Catalina Betancur

Blindsight depends on the lateral geniculate nucleus pp. 373-377

Michael C. Schmid, Sylwia W. Mrowka, Janita Turchi, Richard C. Saunders, Melanie Wilke, Andrew J. Peters, Frank Q. Ye and David A. Leopold

Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning pp. 378-382

Hai Song, Jianxin Hu, Wen Chen, Gene Elliott, Philipp Andre, Bo Gao and Yingzi Yang

Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans pp. 383-387

Eric L. Greer, Travis J. Maures, Anna G. Hauswirth, Erin M. Green, Dena S. Leeman, Géraldine S. Maro, Shuo Han, Max R. Banko, Or Gozani and Anne Brunet

Relationship between nucleosome positioning and DNA methylation pp. 388-392

Ramakrishna K. Chodavarapu, Suhua Feng, Yana V. Bernatavichute, Pao-Yang Chen, Hume Stroud, Yanchun Yu, Jonathan A. Hetzel, Frank Kuo, Jin Kim, Shawn J. Cokus, David Casero, Maria Bernal, Peter Huijser, Amander T. Clark, Ute Krämer, Sabeeha S. Merchant, Xiaoyu Zhang, Steven E. Jacobsen and Matteo Pellegrini

Structure of the gating ring from the human large-conductance Ca2+-gated K+ channel pp. 393-397

Yunkun Wu, Yi Yang, Sheng Ye and Youxing Jiang

Erratum: Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence pp. 398-398

Hui-Kuan Lin, Zhenbang Chen, Guocan Wang, Caterina Nardella, Szu-Wei Lee, Chia-Hsin Chan, Wei-Lei Yang, Jing Wang, Ainara Egia, Keiichi I. Nakayama, Carlos Cordon-Cardo, Julie Teruya-Feldstein and Pier Paolo Pandolfi

Erratum: Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome pp. 398-398

Louise E. Reynolds, Alan R. Watson, Marianne Baker, Tania A. Jones, Gabriela D’Amico, Stephen D. Robinson, Carine Joffre, Sarah Garrido-Urbani, Juan Carlos Rodriguez-Manzaneque, Estefanía Martino-Echarri, Michel Aurrand-Lions, Denise Sheer, Franca Dagna-Bricarelli, Dean Nizetic, Christopher J. McCabe, Andrew S. Turnell, Stephanie Kermorgant, Beat A. Imhof, Ralf H. Adams, Elizabeth M. C. Fisher, Victor L. J. Tybulewicz, Ian R. Hart and Kairbaan M. Hodivala-Dilke

Michael Ehlers pp. 401-401

Virginia Gewin

The way back pp. 402-403

Quirin Schiermeier

Gravity's whispers pp. 406-406

Gregory Benford

2010, volume 466, articles 7303

Journal club pp. 163-163

Tecumseh Fitch

China outlines deep-sea ambitions pp. 166-166

Jane Qiu

Journals step up plagiarism policing pp. 167-167

Declan Butler

Solar System showdown pp. 168-169

Eric Hand

Few fishy facts found in climate report pp. 170-170

Quirin Schiermeier

EU research funds to be diverted to fusion reactor pp. 171-171

Geoff Brumfiel

NIH may open access to clinical facility pp. 172-172

Meredith Wadman

Evolution: Dreampond revisited pp. 174-175

Laura Spinney

Palaeoanthropology: Disputed ground pp. 176-178

Rex Dalton

Unify guidelines for reviewing embryonic stem-cell research pp. 179-179

Josephine Johnston

Metrics: journal's impact factor skewed by a single paper pp. 179-179

Jordan D. Dimitrov, Srini V. Kaveri and Jagadeesh Bayry

Metrics: don't dismiss journals with a low impact factor pp. 179-179

Jay M. Fitzsimmons and Jeffrey H. Skevington

Metrics: include refereeing as part of performance rating pp. 179-179

Pedro Cintas and Elena Paoletti

Securing a future for chimpanzees pp. 180-181

Jane Goodall and Lilian Pintea

How to defend against future oil spills pp. 182-183

Arne Jernelöv

The business of biodiversity pp. 184-185

Ricardo Bayon and Michael Jenkins

Who controls malaria control? pp. 186-187

Awa-Marie Coll-Seck

Making the mundane urbane pp. 187-188

David Bodanis

Pioneers of plant genetics to flower on stage pp. 188-188

Georgina Ferry

Early human northerners pp. 189-190

Andrew P. Roberts and Rainer Grün

Revelations of the fullerenes pp. 191-192

Yoshihiro Iwasa

Sensing tension pp. 192-193

Andrew D. Doyle and Kenneth M. Yamada

More than the sum of its parts pp. 193-194

Jan H. van Esch

MicroRNA knocks down cocaine pp. 194-195

Marina R. Picciotto

A chink in the armour? pp. 195-196

Jeff Flowers

Striatal microRNA controls cocaine intake through CREB signalling pp. 197-202

Jonathan A. Hollander, Heh-In Im, Antonio L. Amelio, Jannet Kocerha, Purva Bali, Qun Lu, David Willoughby, Claes Wahlestedt, Michael D. Conkright and Paul J. Kenny

Structural mechanism of C-type inactivation in K+ channels pp. 203-208

Luis G. Cuello, Vishwanath Jogini, D. Marien Cortes and Eduardo Perozo

A 300-parsec-long jet-inflated bubble around a powerful microquasar in the galaxy NGC 7793 pp. 209-212

Manfred W. Pakull, Roberto Soria and Christian Motch

The size of the proton pp. 213-216

Randolf Pohl, Aldo Antognini, François Nez, Fernando D. Amaro, François Biraben, João M. R. Cardoso, Daniel S. Covita, Andreas Dax, Satish Dhawan, Luis M. P. Fernandes, Adolf Giesen, Thomas Graf, Theodor W. Hänsch, Paul Indelicato, Lucile Julien, Cheng-Yang Kao, Paul Knowles, Eric-Olivier Le Bigot, Yi-Wei Liu, José A. M. Lopes, Livia Ludhova, Cristina M. B. Monteiro, Françoise Mulhauser, Tobias Nebel, Paul Rabinowitz, Joaquim M. F. dos Santos, Lukas A. Schaller, Karsten Schuhmann, Catherine Schwob, David Taqqu, João F. C. A. Veloso and Franz Kottmann

Ultrabright source of entangled photon pairs pp. 217-220

Adrien Dousse, Jan Suffczyński, Alexios Beveratos, Olivier Krebs, Aristide Lemaître, Isabelle Sagnes, Jacqueline Bloch, Paul Voisin and Pascale Senellart

Polymorphism control of superconductivity and magnetism in Cs3C60 close to the Mott transition pp. 221-225

Alexey Y. Ganin, Yasuhiro Takabayashi, Peter Jeglič, Denis Arčon, Anton Potočnik, Peter J. Baker, Yasuo Ohishi, Martin T. McDonald, Manolis D. Tzirakis, Alec McLennan, George R. Darling, Masaki Takata, Matthew J. Rosseinsky and Kosmas Prassides

Increase in African dust flux at the onset of commercial agriculture in the Sahel region pp. 226-228

Stefan Mulitza, David Heslop, Daniela Pittauerova, Helmut W. Fischer, Inka Meyer, Jan-Berend Stuut, Matthias Zabel, Gesine Mollenhauer, James A. Collins, Henning Kuhnert and Michael Schulz

Early Pleistocene human occupation at the edge of the boreal zone in northwest Europe pp. 229-233

Simon A. Parfitt, Nick M. Ashton, Simon G. Lewis, Richard L. Abel, G. Russell Coope, Mike H. Field, Rowena Gale, Peter G. Hoare, Nigel R. Larkin, Mark D. Lewis, Vassil Karloukovski, Barbara A. Maher, Sylvia M. Peglar, Richard C. Preece, John E. Whittaker and Chris B. Stringer

Loss of fish actinotrichia proteins and the fin-to-limb transition pp. 234-237

Jing Zhang, Purva Wagh, Danielle Guay, Luis Sanchez-Pulido, Bhaja K. Padhi, Vladimir Korzh, Miguel A. Andrade-Navarro and Marie-Andrée Akimenko

The genome-wide structure of the Jewish people pp. 238-242

Doron M. Behar, Bayazit Yunusbayev, Mait Metspalu, Ene Metspalu, Saharon Rosset, Jüri Parik, Siiri Rootsi, Gyaneshwer Chaubey, Ildus Kutuev, Guennady Yudkovsky, Elza K. Khusnutdinova, Oleg Balanovsky, Ornella Semino, Luisa Pereira, David Comas, David Gurwitz, Batsheva Bonne-Tamir, Tudor Parfitt, Michael F. Hammer, Karl Skorecki and Richard Villems

Functionally defective germline variants of sialic acid acetylesterase in autoimmunity pp. 243-247

Ira Surolia, Stephan P. Pirnie, Vasant Chellappa, Kendra N. Taylor, Annaiah Cariappa, Jesse Moya, Haoyuan Liu, Daphne W. Bell, David R. Driscoll, Sven Diederichs, Khaleda Haider, Ilka Netravali, Sheila Le, Roberto Elia, Ethan Dow, Annette Lee, Jan Freudenberg, Philip L. De Jager, Yves Chretien, Ajit Varki, Marcy E. MacDonald, Tammy Gillis, Timothy W. Behrens, Donald Bloch, Deborah Collier, Joshua Korzenik, Daniel K. Podolsky, David Hafler, Mandakolathur Murali, Bruce Sands, John H. Stone, Peter K. Gregersen and Shiv Pillai

A random cell motility gradient downstream of FGF controls elongation of an amniote embryo pp. 248-252

Bertrand Bénazéraf, Paul Francois, Ruth E. Baker, Nicolas Denans, Charles D. Little and Olivier Pourquié

Conserved role of intragenic DNA methylation in regulating alternative promoters pp. 253-257

Alika K. Maunakea, Raman P. Nagarajan, Mikhail Bilenky, Tracy J. Ballinger, Cletus D’Souza, Shaun D. Fouse, Brett E. Johnson, Chibo Hong, Cydney Nielsen, Yongjun Zhao, Gustavo Turecki, Allen Delaney, Richard Varhol, Nina Thiessen, Ksenya Shchors, Vivi M. Heine, David H. Rowitch, Xiaoyun Xing, Chris Fiore, Maximiliaan Schillebeeckx, Steven J. M. Jones, David Haussler, Marco A. Marra, Martin Hirst, Ting Wang and Joseph F. Costello

Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b pp. 258-262

Lei Zeng, Qiang Zhang, SiDe Li, Alexander N. Plotnikov, Martin J. Walsh and Ming-Ming Zhou

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics pp. 263-266

Carsten Grashoff, Brenton D. Hoffman, Michael D. Brenner, Ruobo Zhou, Maddy Parsons, Michael T. Yang, Mark A. McLean, Stephen G. Sligar, Christopher S. Chen, Taekjip Ha and Martin A. Schwartz

Single-cell NF-κB dynamics reveal digital activation and analogue information processing pp. 267-271

Savaş Tay, Jacob J. Hughey, Timothy K. Lee, Tomasz Lipniacki, Stephen R. Quake and Markus W. Covert

Structural basis for the coupling between activation and inactivation gates in K+ channels pp. 272-275

Luis G. Cuello, Vishwanath Jogini, D. Marien Cortes, Albert C. Pan, Dominique G. Gagnon, Olivier Dalmas, Julio F. Cordero-Morales, Sudha Chakrapani, Benoît Roux and Eduardo Perozo

Retraction Note: Cellular APOBEC3G restricts HIV-1 infection in resting CD4+ T cells pp. 276-276

Ya-Lin Chiu, Vanessa B. Soros, Jason F. Kreisberg, Kim Stopak, Wes Yonemoto and Warner C. Greene

Heidi Newberg pp. 279-279

Virginia Gewin

Contract investigators pp. 280-281

Heidi Ledford

Trying to let go pp. 284-284

Kerstin Hoppenhaus

2010, volume 466, articles 7302

Journal club pp. 11-11

Marcelo A. Nobrega

What will get sick from the slick? pp. 14-15

Melissa Gaskill

Strikes could 'break' Italy's universities pp. 16-17

Alison Abbott

Space capsule probed for asteroid dust pp. 16-16

David Cyranoski

Stem-cell furore erupts pp. 17-17

Alison Abbott

G8 revisits maternal and child deaths pp. 18-18

Alison Motluk

Gas to displace coal on road to clean energy pp. 19-19

Jeff Tollefson

Strong medicine for French research pp. 20-20

Declan Butler

Profile: The field medic pp. 22-23

Erik Vance

Climate science: An erosion of trust? pp. 24-26

Jeff Tollefson

World view: Entertaining science pp. 27-27

Daniel Sarewitz

Advocacy groups and the economic value of medical research pp. 28-28

Mary Woolley

Develop instruments to monitor volcanic ash fallout pp. 28-28

Freysteinn Sigmundsson and Ármann Höskuldsson

Sino-European research ethics on the right path pp. 28-28

Christoph Rehmann-Sutter

Gender agenda: sex bias can be justified in animal research pp. 28-28

Brad Bolon

Most people are not WEIRD pp. 29-29

Joseph Henrich, Steven J. Heine and Ara Norenzayan

Climate class for business schools pp. 30-30

Genevieve Patenaude

Embracing an uncertain future pp. 31-31

Myles Allen

Books in brief pp. 32-32

Joanne Baker

A life both kind and strange pp. 32-33

W. F. Bynum

Moving in elevated circles pp. 33-33

Martin Kemp

Masterly deceptions brought to light pp. 34-34

Daniel Cressey

X-ray laser peels and cores atoms pp. 35-36

Justin Wark

How to get even with pests pp. 36-37

Lindsay A. Turnbull and Andy Hector

The supernova has two faces pp. 37-38

Daniel Kasen

Snapshot of the network pp. 38-39

Beth Levine and Rama Ranganathan

Invitation to a second round pp. 40-41

Peter Dirks

Origins of multicellularity pp. 41-42

Philip C. J. Donoghue and Jonathan B. Antcliffe

Pulled from a protein's embrace pp. 42-43

William L. Jorgensen

Closing in on evaders pp. 43-44

Tamás Vicsek

Richard Langton Gregory (1923–2010) pp. 45-45

Colin Blakemore

The polar ocean and glacial cycles in atmospheric CO2 concentration pp. 47-55

Daniel M. Sigman, Mathis P. Hain and Gerald H. Haug

Femtosecond electronic response of atoms to ultra-intense X-rays pp. 56-61

L. Young, E. P. Kanter, B. Krässig, Y. Li, A. M. March, S. T. Pratt, R. Santra, S. H. Southworth, N. Rohringer, L. F. DiMauro, G. Doumy, C. A. Roedig, N. Berrah, L. Fang, M. Hoener, P. H. Bucksbaum, J. P. Cryan, S. Ghimire, J. M. Glownia, D. A. Reis, J. D. Bozek, C. Bostedt and M. Messerschmidt

Chromatin regulation by Brg1 underlies heart muscle development and disease pp. 62-67

Calvin T. Hang, Jin Yang, Pei Han, Hsiu-Ling Cheng, Ching Shang, Euan Ashley, Bin Zhou and Ching-Pin Chang

Network organization of the human autophagy system pp. 68-76

Christian Behrends, Mathew E. Sowa, Steven P. Gygi and J. Wade Harper

Spatial organization of the flow of genetic information in bacteria pp. 77-81

Paula Montero Llopis, Audrey F. Jackson, Oleksii Sliusarenko, Ivan Surovtsev, Jennifer Heinritz, Thierry Emonet and Christine Jacobs-Wagner

An asymmetric explosion as the origin of spectral evolution diversity in type Ia supernovae pp. 82-85

K. Maeda, S. Benetti, M. Stritzinger, F. K. Röpke, G. Folatelli, J. Sollerman, S. Taubenberger, K. Nomoto, G. Leloudas, M. Hamuy, M. Tanaka, P. A. Mazzali and N. Elias-Rosa

A macroscopic mechanical resonator driven by mesoscopic electrical back-action pp. 86-90

Joel Stettenheim, Madhu Thalakulam, Feng Pan, Mustafa Bal, Zhonqing Ji, Weiwei Xue, Loren Pfeiffer, K. W. West, M. P. Blencowe and A. J. Rimberg

Tailoring light–matter–spin interactions in colloidal hetero-nanostructures pp. 91-95

Jiatao Zhang, Yun Tang, Kwan Lee and Min Ouyang

Ecosystem response to elevated CO2 levels limited by nitrogen-induced plant species shift pp. 96-99

J. Adam Langley and J. Patrick Megonigal

Large colonial organisms with coordinated growth in oxygenated environments 2.1 Gyr ago pp. 100-104

Abderrazak El Albani, Stefan Bengtson, Donald E. Canfield, Andrey Bekker, Roberto Macchiarelli, Arnaud Mazurier, Emma U. Hammarlund, Philippe Boulvais, Jean-Jacques Dupuy, Claude Fontaine, Franz T. Fürsich, François Gauthier-Lafaye, Philippe Janvier, Emmanuelle Javaux, Frantz Ossa Ossa, Anne-Catherine Pierson-Wickmann, Armelle Riboulleau, Paul Sardini, Daniel Vachard, Martin Whitehouse and Alain Meunier

The giant bite of a new raptorial sperm whale from the Miocene epoch of Peru pp. 105-108

Olivier Lambert, Giovanni Bianucci, Klaas Post, Christian de Muizon, Rodolfo Salas-Gismondi, Mario Urbina and Jelle Reumer

Organic agriculture promotes evenness and natural pest control pp. 109-112

David W. Crowder, Tobin D. Northfield, Michael R. Strand and William E. Snyder

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity pp. 113-117

Lynn Petukhova, Madeleine Duvic, Maria Hordinsky, David Norris, Vera Price, Yutaka Shimomura, Hyunmi Kim, Pallavi Singh, Annette Lee, Wei V. Chen, Katja C. Meyer, Ralf Paus, Colin A. B. Jahoda, Christopher I. Amos, Peter K. Gregersen and Angela M. Christiano

The male mouse pheromone ESP1 enhances female sexual receptive behaviour through a specific vomeronasal receptor pp. 118-122

Sachiko Haga, Tatsuya Hattori, Toru Sato, Koji Sato, Soichiro Matsuda, Reiko Kobayakawa, Hitoshi Sakano, Yoshihiro Yoshihara, Takefumi Kikusui and Kazushige Touhara

Sensitivity to perturbations in vivo implies high noise and suggests rate coding in cortex pp. 123-127

Michael London, Arnd Roth, Lisa Beeren, Michael Häusser and Peter E. Latham

Spatiotemporal regulation of cell-cycle genes by SHORTROOT links patterning and growth pp. 128-132

R. Sozzani, H. Cui, M. A. Moreno-Risueno, W. Busch, J. M. Van Norman, T. Vernoux, S. M. Brady, W. Dewitte, J. A. H. Murray and P. N. Benfey

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271 pp. 133-137

Alexander D. Boiko, Olga V. Razorenova, Matt van de Rijn, Susan M. Swetter, Denise L. Johnson, Daphne P. Ly, Paris D. Butler, George P. Yang, Benzion Joshua, Michael J. Kaplan, Michael T. Longaker and Irving L. Weissman

SCFCyclin F controls centrosome homeostasis and mitotic fidelity through CP110 degradation pp. 138-142

Vincenzo D’Angiolella, Valerio Donato, Sangeetha Vijayakumar, Anita Saraf, Laurence Florens, Michael P. Washburn, Brian Dynlacht and Michele Pagano

Leslie Vosshall pp. 145-145

Virginia Gewin

Mile-high dreams pp. 146-147

Laura Cassiday

The end of God pp. 150-150

Shelly Li