NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

Paras K. Anand, R. K. Subbarao Malireddi, John R. Lukens, Peter Vogel, John Bertin, Mohamed Lamkanfi and Thirumala-Devi Kanneganti ()
Additional contact information
Paras K. Anand: St. Jude Children’s Research Hospital
R. K. Subbarao Malireddi: St. Jude Children’s Research Hospital
John R. Lukens: St. Jude Children’s Research Hospital
Peter Vogel: Animal Resources Center and the Veterinary Pathology Core, St. Jude Children’s Research Hospital
John Bertin: Pattern Recognition Receptor DPU, Immuno-Inflammation TA, GlaxoSmithKline, Collegeville, Pennsylvania 19426, USA
Mohamed Lamkanfi: Ghent University, B-9000 Ghent, Belgium
Thirumala-Devi Kanneganti: St. Jude Children’s Research Hospital

Nature, 2012, vol. 488, issue 7411, 389-393

Abstract: The Nod-like receptor family member NLRP6 is characterized and shown to be a negative regulator of inflammatory signalling, dampening host responses against bacterial infections and impeding bacterial clearance.

Date: 2012
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://www.nature.com/articles/nature11250 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:488:y:2012:i:7411:d:10.1038_nature11250

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature11250

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().