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2008, volume 453, articles 7199

Journal club pp. 1147-1147

Seth Lloyd

Gene-testing firms face legal battle pp. 1148-1149

Meredith Wadman

Biogen fights takeover bid pp. 1149-1149

Heidi Ledford

Scientists get online news aggregator pp. 1149-1149

Declan Butler

Payback time pp. 1150-1151

Geoff Brumfiel

When water gushed on Mars pp. 1153-1153

Eric Hand

Population genomics for fruitflies pp. 1154-1155

Heidi Ledford

Online anthropology draws protest from aboriginal group pp. 1155-1155

Tony Scully

Planetary science: Tunguska at 100 pp. 1157-1159

Duncan Steel

Planetary science: The hole at the bottom of the Moon pp. 1160-1163

Eric Hand

Planetary science: The burger bar that saved the world pp. 1164-1168

David Chandler

Agronomy and plant breeding are key to combating food crisis pp. 1177-1177

Lucas Borrás and Gustavo A. Slafer

The ethical basis of the null hypothesis pp. 1177-1177

John Pastor

Stem-cell urological treatment was not carried out illegally pp. 1177-1177

Hannes Strasser

What Spaceguard did pp. 1178-1179

Alan Harris

The end of the line? pp. 1180-1181

Daniel Pauly

Making genetic history pp. 1181-1182

Jerry A. Coyne

Swayonomics pp. 1182-1183

Michael Shermer

Q&A: Travels with a paintbrush pp. 1183-1183

Daniel Cressey

In Retrospect: Lucifer's Hammer pp. 1184-1184

Oliver Morton

Message from the heavens pp. 1185-1185

Martin Kemp

Beyond the notes pp. 1186-1187

Nicholas Cook

The other beetle-hunter pp. 1188-1190

Andrew Berry and Janet Browne

Forming the martian great divide pp. 1191-1192

Walter S. Kiefer

Out of sight, but not out of mind pp. 1193-1194

Seth M. Tomchik and Ronald L. Davis

A lifeline for suffocating tissues pp. 1194-1195

Massimiliano Mazzone and Peter Carmeliet

Sun, sea and ozone destruction pp. 1195-1196

Roland von Glasow

Bias at the ballot box pp. 1197-1197

Tim Lincoln

Power sequencing pp. 1197-1198

Brenton R. Graveley

Ventastega curonica and the origin of tetrapod morphology pp. 1199-1204

Per E. Ahlberg, Jennifer A. Clack, Ervīns Lukševičs, Henning Blom and Ivars Zupiņš

Scaling of the BMP activation gradient in Xenopus embryos pp. 1205-1211

Danny Ben-Zvi, Ben-Zion Shilo, Abraham Fainsod and Naama Barkai

The Borealis basin and the origin of the martian crustal dichotomy pp. 1212-1215

Jeffrey C. Andrews-Hanna, Maria T. Zuber and W. Bruce Banerdt

Mega-impact formation of the Mars hemispheric dichotomy pp. 1216-1219

Margarita M. Marinova, Oded Aharonson and Erik Asphaug

Implications of an impact origin for the martian hemispheric dichotomy pp. 1220-1223

F. Nimmo, S. D. Hart, D. G. Korycansky and C. B. Agnor

A BCS-like gap in the superconductor SmFeAsO0.85F0.15 pp. 1224-1227

T. Y. Chen, Z. Tesanovic, R. H. Liu, X. H. Chen and C. L. Chien

The total synthesis of (-)-cyanthiwigin F by means of double catalytic enantioselective alkylation pp. 1228-1231

John A. Enquist and Brian M. Stoltz

Extensive halogen-mediated ozone destruction over the tropical Atlantic Ocean pp. 1232-1235

Katie A. Read, Anoop S. Mahajan, Lucy J. Carpenter, Mathew J. Evans, Bruno V. E. Faria, Dwayne E. Heard, James R. Hopkins, James D. Lee, Sarah J. Moller, Alastair C. Lewis, Luis Mendes, James B. McQuaid, Hilke Oetjen, Alfonso Saiz-Lopez, Michael J. Pilling and John M. C. Plane

Explosive volcanism on the ultraslow-spreading Gakkel ridge, Arctic Ocean pp. 1236-1238

Robert A. Sohn, Claire Willis, Susan Humphris, Timothy M. Shank, Hanumant Singh, Henrietta N. Edmonds, Clayton Kunz, Ulf Hedman, Elisabeth Helmke, Michael Jakuba, Bengt Liljebladh, Julia Linder, Christopher Murphy, Ko-ichi Nakamura, Taichi Sato, Vera Schlindwein, Christian Stranne, Maria Tausenfreund, Lucia Upchurch, Peter Winsor, Martin Jakobsson and Adam Soule

Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution pp. 1239-1243

Brian T. Wilhelm, Samuel Marguerat, Stephen Watt, Falk Schubert, Valerie Wood, Ian Goodhead, Christopher J. Penkett, Jane Rogers and Jürg Bähler

Analysis of a spatial orientation memory in Drosophila pp. 1244-1247

Kirsa Neuser, Tilman Triphan, Markus Mronz, Burkhard Poeck and Roland Strauss

Hippocampus-independent phase precession in entorhinal grid cells pp. 1248-1252

Torkel Hafting, Marianne Fyhn, Tora Bonnevie, May-Britt Moser and Edvard I. Moser

Rapid strengthening of thalamo-amygdala synapses mediates cue–reward learning pp. 1253-1257

Kay M. Tye, Garret D. Stuber, Bram de Ridder, Antonello Bonci and Patricia H. Janak

Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants pp. 1258-1261

Patrick J. Collins, Lesley F. Haire, Yi Pu Lin, Junfeng Liu, Rupert J. Russell, Philip A. Walker, John J. Skehel, Stephen R. Martin, Alan J. Hay and Steven J. Gamblin

Assembly reflects evolution of protein complexes pp. 1262-1265

Emmanuel D. Levy, Elisabetta Boeri Erba, Carol V. Robinson and Sarah A. Teichmann

Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins pp. 1266-1270

Nathan HyunJoong Joh, Andrew Min, Salem Faham, Julian P. Whitelegge, Duan Yang, Virgil L. Woods and James U. Bowie

Structural basis for EGFR ligand sequestration by Argos pp. 1271-1275

Daryl E. Klein, Steven E. Stayrook, Fumin Shi, Kartik Narayan and Mark A. Lemmon

Translation factors promote the formation of two states of the closed-loop mRNP pp. 1276-1280

Nadia Amrani, Shubhendu Ghosh, David A. Mangus and Allan Jacobson

Pruning the prickly path to industry pp. 1281-1281

Gene Russo

James Halpert, Associate Dean for Scientific Affairs, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego pp. 1282-1282

Virginia Gewin

Postdoc competencies pp. 1282-1282

Lisa Curtis, Keith Micoli and Jennifer Reineke Pohlhaus

Cool and collected pp. 1282-1282

Aliza le Roux

Dead yellow pp. 1284-1284

Tanith Lee

2008, volume 453, articles 7198

Journal club pp. 961-961

John P. Quinn

Japan ramps up patent effort to keep iPS lead pp. 962-963

David Cyranoski

Institutes in pharma cash probe pp. 963-963

Heidi Ledford

Lab disinfectant harms mouse fertility pp. 964-964

Brendan Maher

Astronomical wordplay keeps them guessing pp. 965-965

Eric Hand

Universal law of coiling pp. 966-966

Philip Ball

UK universities in bed with the military pp. 967-967

Geoff Brumfiel

Tierra del Fuego: the beavers must die pp. 968-968

Charles Choi

Meteorology: Taming the sky pp. 970-974

Jane Qiu and Daniel Cressey

Funding: The research revolution pp. 975-976

Geoff Brumfiel

Fewer academics could be the answer to insufficient grants pp. 978-978

Andrew Doig

Working together to put molecules on the map pp. 978-978

Dawn Field

Decoherence does not get rid of the quantum paradox pp. 978-979

Nikolaus von Stillfried

Ventures should not overstate their aims just to secure funding pp. 979-979

Mike Hulme and Suraje Dessai

Digital identifiers work for articles, so why not for authors? pp. 979-979

Raf Aerts

Europe needs to protect its transgenic crop research pp. 979-979

Howard J. Atkinson and Peter E. Urwin

Repairing research integrity pp. 980-982

Sandra L. Titus, James A. Wells and Lawrence J. Rhoades

Quantum weirdness and surrealism pp. 983-984

Philip Ball

Wish you were here? pp. 984-985

Joseph Cirincione

Memories revisited pp. 985-985

Alison Abbott

Winning Darwin design takes root pp. 986-986

Colin Martin

Building nations after conflict pp. 986-987

Peter Turchin

Q&A: Insight into Einstein pp. 987-987

Jascha Hoffman

Playing by numbers pp. 988-989

Damián Zanette

A century of puzzling pp. 990-991

Andrew Robinson

Colourful future for MRI pp. 993-994

Richard Bowtell

Brain control of a helping hand pp. 994-995

John F. Kalaska

Deconstructing oncogenesis pp. 995-996

Ji Luo and Stephen J. Elledge

On the border pp. 996-997

Liesbeth Venema

Modelling collagen diseases pp. 998-999

Barbara Brodsky and Jean Baum

The amphioxus unleashed pp. 999-1000

Henry Gee

Prospecting for an iron age pp. 1000-1001

Paul M. Grant

Christopher Curtis (1939–2008) pp. 1002-1002

Indira Nath

Quantum coherence pp. 1003-1003

Karen Southwell

Quantifying entanglement in macroscopic systems pp. 1004-1007

Vlatko Vedral

Entangled states of trapped atomic ions pp. 1008-1015

Rainer Blatt and David Wineland

Quantum coherence and entanglement with ultracold atoms in optical lattices pp. 1016-1022

Immanuel Bloch

The quantum internet pp. 1023-1030

H. J. Kimble

Superconducting quantum bits pp. 1031-1042

John Clarke and Frank K. Wilhelm

Coherent manipulation of single spins in semiconductors pp. 1043-1049

Ronald Hanson and David D. Awschalom

Induction and effector functions of TH17 cells pp. 1051-1057

Estelle Bettelli, Thomas Korn, Mohamed Oukka and Vijay K. Kuchroo

Micro-engineered local field control for high-sensitivity multispectral MRI pp. 1058-1063

Gary Zabow, Stephen Dodd, John Moreland and Alan Koretsky

The amphioxus genome and the evolution of the chordate karyotype pp. 1064-1071

Nicholas H. Putnam, Thomas Butts, David E. K. Ferrier, Rebecca F. Furlong, Uffe Hellsten, Takeshi Kawashima, Marc Robinson-Rechavi, Eiichi Shoguchi, Astrid Terry, Jr-Kai Yu, E`lia Benito-Gutiérrez, Inna Dubchak, Jordi Garcia-Fernàndez, Jeremy J. Gibson-Brown, Igor V. Grigoriev, Amy C. Horton, Pieter J. de Jong, Jerzy Jurka, Vladimir V. Kapitonov, Yuji Kohara, Yoko Kuroki, Erika Lindquist, Susan Lucas, Kazutoyo Osoegawa, Len A. Pennacchio, Asaf A. Salamov, Yutaka Satou, Tatjana Sauka-Spengler, Jeremy Schmutz, Tadasu Shin-I, Atsushi Toyoda, Marianne Bronner-Fraser, Asao Fujiyama, Linda Z. Holland, Peter W. H. Holland, Nori Satoh and Daniel S. Rokhsar

PML targeting eradicates quiescent leukaemia-initiating cells pp. 1072-1078

Keisuke Ito, Rosa Bernardi, Alessandro Morotti, Sahoko Matsuoka, Giuseppe Saglio, Yasuo Ikeda, Jacalyn Rosenblatt, David E. Avigan, Julie Teruya-Feldstein and Pier Paolo Pandolfi

Surprising dissimilarities in a newly formed pair of ‘identical twin’ stars pp. 1079-1082

Keivan G. Stassun, Robert D. Mathieu, Phillip A. Cargile, Alicia N. Aarnio, Eric Stempels and Aaron Geller

Jovian-like aurorae on Saturn pp. 1083-1085

Tom Stallard, Steve Miller, Henrik Melin, Makenzie Lystrup, Stan W. H. Cowley, Emma J. Bunce, Nicholas Achilleos and Michele Dougherty

Nanoscale holographic interferometry for strain measurements in electronic devices pp. 1086-1089

Martin Hÿtch, Florent Houdellier, Florian Hüe and Etienne Snoeck

Improved estimates of upper-ocean warming and multi-decadal sea-level rise pp. 1090-1093

Catia M. Domingues, John A. Church, Neil J. White, Peter J. Gleckler, Susan E. Wijffels, Paul M. Barker and Jeff R. Dunn

Cytokinin and auxin interaction in root stem-cell specification during early embryogenesis pp. 1094-1097

Bruno Müller and Jen Sheen

Cortical control of a prosthetic arm for self-feeding pp. 1098-1101

Meel Velliste, Sagi Perel, M. Chance Spalding, Andrew S. Whitford and Andrew B. Schwartz

Neural substrates of vocalization feedback monitoring in primate auditory cortex pp. 1102-1106

Steven J. Eliades and Xiaoqin Wang

RNA toxicity is a component of ataxin-3 degeneration in Drosophila pp. 1107-1111

Ling-Bo Li, Zhenming Yu, Xiuyin Teng and Nancy M. Bonini

Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype pp. 1112-1116

Helene R. McMurray, Erik R. Sampson, George Compitello, Conan Kinsey, Laurel Newman, Bradley Smith, Shaw-Ree Chen, Lev Klebanov, Peter Salzman, Andrei Yakovlev and Hartmut Land

Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia pp. 1117-1121

Keizo Kanasaki, Kristin Palmsten, Hikaru Sugimoto, Shakil Ahmad, Yuki Hamano, Liang Xie, Samuel Parry, Hellmut G. Augustin, Vincent H. Gattone, Judah Folkman, Jerome F. Strauss and Raghu Kalluri

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants pp. 1122-1126

Stephanie C. Eisenbarth, Oscar R. Colegio, William O’Connor, Fayyaz S. Sutterwala and Richard A. Flavell

Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins pp. 1127-1131

Abbhirami Rajagopal, Anita U. Rao, Julio Amigo, Meng Tian, Sanjeev K. Upadhyay, Caitlin Hall, Suji Uhm, M. K. Mathew, Mark D. Fleming, Barry H. Paw, Michael Krause and Iqbal Hamza

Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient pp. 1132-1136

Brian G. Fuller, Michael A. Lampson, Emily A. Foley, Sara Rosasco-Nitcher, Kim V. Le, Page Tobelmann, David L. Brautigan, P. Todd Stukenberg and Tarun M. Kapoor

Prospects pp. 1137-1137

Gene Russo

Taking the industry road pp. 1138-1139

Robin Mejia

Neil Turok, executive director, Perimeter Institute for Theoretical Physics, Waterloo, Ontario, Canada pp. 1140-1140

Virginia Gewin

The hunt for new US drug regulators pp. 1140-1140

Virginia Gewin

I'm an alien pp. 1140-1140

Jon Yearsley

Travel by numbers pp. 1142-1142

Gareth D. Jones

2008, volume 453, articles 7197

Journal club pp. 827-827

David Beerling

Egg shortage hits race to clone human stem cells pp. 828-829

Brendan Maher

Fusion reactor faces cost hike pp. 829-829

Geoff Brumfiel

The winding road from ideas to income pp. 830-831

Meredith Wadman

Swiss court bans work on macaque brains pp. 833-833

Alison Abbott

Near-perfect 'black' pp. 834-834

Philip Ball

NIH responds to critics on peer review pp. 835-835

Meredith Wadman

A delicate balance pp. 838-838

David Goldston

Translational research: Crossing the valley of death pp. 840-842

Declan Butler

Translational Research: The full cycle pp. 843-845

Heidi Ledford

Translational research: A case history pp. 846-849

Helen Pearson

European research system must not go bananas pp. 850-850

Andre Geim

Large projects can create useful partnerships pp. 850-850

Josef Settele, Joachim Spangenberg and Ingolf Kühn

European research needs a dash of anarchy pp. 850-850

Theo Wallimann

Follow the leader pp. 851-852

Kaori Tsuji and Kiichiro Tsutani

A new relationship pp. 853-854

Bill Destler

A prescription for public health pp. 855-856

Merrill Goozner

Complementary cures tested pp. 856-857

Toby Murcott

Suppressing science pp. 857-858

Dick Taverne

Raising the roof pp. 859-860

Michael Barron

Molecular cloaking devices pp. 861-862

Thomas Kodadek

Cool it, baby pp. 862-863

Markku Räsänen

Guardian caterpillars pp. 863-863

Christopher Surridge

Genetics lends a hand pp. 863-864

Stéphane Palfi and Bechir Jarraya

A neutrino's wobble? pp. 864-865

Philip M. Walker

Paralysed by disorder pp. 866-866

Daniel A. Steck

Willis E. Lamb Jr (1913–2008) pp. 867-867

Murray Sargent

What we can do and what we cannot do with fMRI pp. 869-878

Nikos K. Logothetis

A phosphatase cascade by which rewarding stimuli control nucleosomal response pp. 879-884

Alexandre Stipanovich, Emmanuel Valjent, Miriam Matamales, Akinori Nishi, Jung-Hyuck Ahn, Matthieu Maroteaux, Jesus Bertran-Gonzalez, Karen Brami-Cherrier, Hervé Enslen, Anne-Gaëlle Corbillé, Odile Filhol, Angus C. Nairn, Paul Greengard, Denis Hervé and Jean-Antoine Girault

Structural basis for the regulated protease and chaperone function of DegP pp. 885-890

Tobias Krojer, Justyna Sawa, Eva Schäfer, Helen R. Saibil, Michael Ehrmann and Tim Clausen

Direct observation of Anderson localization of matter waves in a controlled disorder pp. 891-894

Juliette Billy, Vincent Josse, Zhanchun Zuo, Alain Bernard, Ben Hambrecht, Pierre Lugan, David Clément, Laurent Sanchez-Palencia, Philippe Bouyer and Alain Aspect

Anderson localization of a non-interacting Bose–Einstein condensate pp. 895-898

Giacomo Roati, Chiara D’Errico, Leonardo Fallani, Marco Fattori, Chiara Fort, Matteo Zaccanti, Giovanni Modugno, Michele Modugno and Massimo Inguscio

Magnetic order close to superconductivity in the iron-based layered LaO1-xF x FeAs systems pp. 899-902

Clarina de la Cruz, Q. Huang, J. W. Lynn, Jiying Li, W. Ratcliff, J. L. Zarestky, H. A. Mook, G. F. Chen, J. L. Luo, N. L. Wang and Pengcheng Dai

Two-band superconductivity in LaFeAsO0.89F0.11 at very high magnetic fields pp. 903-905

F. Hunte, J. Jaroszynski, A. Gurevich, D. C. Larbalestier, R. Jin, A. S. Sefat, M. A. McGuire, B. C. Sales, D. K. Christen and D. Mandrus

Capture of hydroxymethylene and its fast disappearance through tunnelling pp. 906-909

Peter R. Schreiner, Hans Peter Reisenauer, Frank C. Pickard Iv, Andrew C. Simmonett, Wesley D. Allen, Edit Mátyus and Attila G. Császár

Continental mantle signature of Bushveld magmas and coeval diamonds pp. 910-913

Stephen H. Richardson and Steven B. Shirey

Ultrasonic frogs show hyperacute phonotaxis to female courtship calls pp. 914-916

Jun-Xian Shen, Albert S. Feng, Zhi-Min Xu, Zu-Lin Yu, Victoria S. Arch, Xin-Jian Yu and Peter M. Narins

Perceptual accuracy and conflicting effects of certainty on risk-taking behaviour pp. 917-920

Sharoni Shafir, Taly Reich, Erez Tsur, Ido Erev and Arnon Lotem

Towards a transgenic model of Huntington’s disease in a non-human primate pp. 921-924

Shang-Hsun Yang, Pei-Hsun Cheng, Heather Banta, Karolina Piotrowska-Nitsche, Jin-Jing Yang, Eric C. H. Cheng, Brooke Snyder, Katherine Larkin, Jun Liu, Jack Orkin, Zhi-Hui Fang, Yoland Smith, Jocelyne Bachevalier, Stuart M. Zola, Shi-Hua Li, Xiao-Jiang Li and Anthony W. S. Chan

Substrate-targeting γ-secretase modulators pp. 925-929

Thomas L. Kukar, Thomas B. Ladd, Maralyssa A. Bann, Patrick C. Fraering, Rajeshwar Narlawar, Ghulam M. Maharvi, Brent Healy, Robert Chapman, Alfred T. Welzel, Robert W. Price, Brenda Moore, Vijayaraghavan Rangachari, Bernadette Cusack, Jason Eriksen, Karen Jansen-West, Christophe Verbeeck, Debra Yager, Christopher Eckman, Wenjuan Ye, Sarah Sagi, Barbara A. Cottrell, Justin Torpey, Terrone L. Rosenberry, Abdul Fauq, Michael S. Wolfe, Boris Schmidt, Dominic M. Walsh, Edward H. Koo and Todd E. Golde

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer pp. 930-934

Ryohei Sekido and Robin Lovell-Badge

Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling pp. 935-939

Jennifer S. Ziegenfuss, Romi Biswas, Michelle A. Avery, Kyoungja Hong, Amy E. Sheehan, Yee-Guide Yeung, E. Richard Stanley and Marc R. Freeman

Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate pp. 940-943

Ferdia A. Gallagher, Mikko I. Kettunen, Sam E. Day, Hu De-En, Jan Henrik Ardenkjær-Larsen, René in ‘t Zandt, Pernille R. Jensen, Magnus Karlsson, Klaes Golman, Mathilde H. Lerche and Kevin M. Brindle

Global control of cell-cycle transcription by coupled CDK and network oscillators pp. 944-947

David A. Orlando, Charles Y. Lin, Allister Bernard, Jean Y. Wang, Joshua E. S. Socolar, Edwin S. Iversen, Alexander J. Hartemink and Steven B. Haase

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions pp. 948-951

Lars Guelen, Ludo Pagie, Emilie Brasset, Wouter Meuleman, Marius B. Faza, Wendy Talhout, Bert H. Eussen, Annelies de Klein, Lodewyk Wessels, Wouter de Laat and Bas van Steensel

Erratum: Lethargus is a Caenorhabditis elegans sleep-like state pp. 952-952

David M. Raizen, John E. Zimmerman, Matthew H. Maycock, Uyen D. Ta, Young-jai You, Meera V. Sundaram and Allan I. Pack

US universities may have to chip in more for researchers' salaries pp. 953-953

Gene Russo

Cato Laurencin, vice-president for health affairs, University of Connecticut Health Center, and dean, University of Connecticut School of Medicine, Farmington pp. 954-954

Virginia Gewin

A route to postdoc diversity pp. 954-954

Jill U. Adams

Winning a plant campaign pp. 954-954

Zachary Lippman

Permanent position pp. 956-956

John Gilbey

2008, volume 453, articles 7196

Journal club pp. 701-701

Uri Alon

Russian science academy rejects Putin ally pp. 702-703

Quirin Schiermeier

Mars reveals early mysteries pp. 703-703

Eric Hand

Japanese nuclear plant in quake risk pp. 704-704

David Cyranoski

UN decision puts brakes on ocean fertilization pp. 704-704

Jeff Tollefson

Physicists to target neutrinos pp. 705-705

Eric Hand

The four-year fight for biological art pp. 707-707

Rachel Courtland

Here's looking at you, kid pp. 708-708

Zeeya Merali

Biological tools revamp disease classification pp. 709-709

Erika Check Hayden

Planetary science: Stranger in a strange land pp. 712-713

Eric Hand

Ecological modelling: The mathematical mirror to animal nature pp. 714-716

Mark Buchanan

Palaeobiology: The Cambrian smorgasbord pp. 717-718

Arran Frood

Evolutionary theory: it's on the school syllabus in Mexico pp. 719-719

Antonio Lazcano, Arturo Becerra and Juli Peretó

Evolutionary theory: don't skimp on teaching its history pp. 719-719

David M. Williams and Malte C. Ebach

Learning to navigate the geography of citation indexes pp. 719-719

Debbie Chaves

Vaccine failure is not a 'crisis' for HIV research pp. 719-720

Richard Jefferys

Fixing hiring practices means asking the right question pp. 720-720

Emilio Artacho

Germline modification carries risk of major social harm pp. 720-720

Marcy Darnovsky

Global database is needed to support adaptation science pp. 720-720

Elvira S. Poloczanska, Alistair J. Hobday and Anthony J. Richardson

Command and control pp. 721-722

Sandra Knapp

Staving off the global food crisis pp. 722-723

Charles Timmer

Horse power unbridled pp. 723-723

Josie Glausiusz

How the car became king pp. 724-725

Marcial Echenique

In Retrospect: The chromosome trail pp. 725-725

Robert A. Weinberg

Talk of the tone pp. 726-727

Aniruddh D. Patel

Protein fossils live on as RNA pp. 729-731

Rajkumar Sasidharan and Mark Gerstein

An easier route to high harmony pp. 731-733

Mark I. Stockman

Order in the lung pp. 733-734

David Warburton

Charge states in transition pp. 735-735

Raffaele Resta

Optical lattices pp. 736-738

Markus Greiner and Simon Fölling

The determination of the structure of Saturn’s F ring by nearby moonlets pp. 739-744

Carl D. Murray, Kevin Beurle, Nicholas J. Cooper, Michael W. Evans, Gareth A. Williams and Sébastien Charnoz

The branching programme of mouse lung development pp. 745-750

Ross J. Metzger, Ophir D. Klein, Gail R. Martin and Mark A. Krasnow

A two-tiered mechanism for stabilization and immobilization of E-cadherin pp. 751-756

Matthieu Cavey, Matteo Rauzi, Pierre-François Lenne and Thomas Lecuit

High-harmonic generation by resonant plasmon field enhancement pp. 757-760

Seungchul Kim, Jonghan Jin, Young-Jin Kim, In-Yong Park, Yunseok Kim and Seung-Woo Kim

Superconductivity at 43 K in SmFeAsO1-xF x pp. 761-762

X. H. Chen, T. Wu, G. Wu, R. H. Liu, H. Chen and D. F. Fang

Charge self-regulation upon changing the oxidation state of transition metals in insulators pp. 763-766

Hannes Raebiger, Stephan Lany and Alex Zunger

Hydrogen sulphide release to surface waters at the Precambrian/Cambrian boundary pp. 767-769

Martin Wille, Thomas F. Nägler, Bernd Lehmann, Stefan Schröder and Jan D. Kramers

Simultaneous teleseismic and geodetic observations of the stick–slip motion of an Antarctic ice stream pp. 770-774

Douglas A. Wiens, Sridhar Anandakrishnan, J. Paul Winberry and Matt A. King

Cladistic analysis of continuous modularized traits provides phylogenetic signals in Homo evolution pp. 775-778

Rolando González-José, Ignacio Escapa, Walter A. Neves, Rubén Cúneo and Héctor M. Pucciarelli

Understanding individual human mobility patterns pp. 779-782

Marta C. González, Cesar Hidalgo and Albert-László Barabási

Dynamics of fat cell turnover in humans pp. 783-787

Kirsty L. Spalding, Erik Arner, Pål O. Westermark, Samuel Bernard, Bruce A. Buchholz, Olaf Bergmann, Lennart Blomqvist, Johan Hoffstedt, Erik Näslund, Tom Britton, Hernan Concha, Moustapha Hassan, Mikael Rydén, Jonas Frisén and Peter Arner

The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes pp. 788-792

Austin R. Graves, Patricia K. Curran, Carolyn L. Smith and Joseph A. Mindell

Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells pp. 793-797

Yoshinori Kawamura, Kuniaki Saito, Taishin Kin, Yukiteru Ono, Kiyoshi Asai, Takafumi Sunohara, Tomoko N. Okada, Mikiko C. Siomi and Haruhiko Siomi

An endogenous small interfering RNA pathway in Drosophila pp. 798-802

Benjamin Czech, Colin D. Malone, Rui Zhou, Alexander Stark, Catherine Schlingeheyde, Monica Dus, Norbert Perrimon, Manolis Kellis, James A. Wohlschlegel, Ravi Sachidanandam, Gregory J. Hannon and Julius Brennecke

The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs pp. 803-806

Katsutomo Okamura, Wei-Jen Chung, J. Graham Ruby, Huili Guo, David P. Bartel and Eric C. Lai

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α pp. 807-811

Jordi Rius, Monica Guma, Christian Schachtrup, Katerina Akassoglou, Annelies S. Zinkernagel, Victor Nizet, Randall S. Johnson, Gabriel G. Haddad and Michael Karin

Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation pp. 812-816

Robert K. McGinty, Jaehoon Kim, Champak Chatterjee, Robert G. Roeder and Tom W. Muir

Europe aims for more flexibility and job security for researchers pp. 817-817

Paul Smaglik

Beyond rocket science pp. 818-820

Paul Smaglik

The invisible hand pp. 822-822

Allan M. Lees

2008, volume 453, articles 7195

Journal club pp. 567-567

Nathan Wolfe

Venerable institute gets a refit pp. 568-569

Matt Brown

Climate anomaly is an artefact pp. 569-569

Quirin Schiermeier

Genetic testing for everyone pp. 570-571

Helen Pearson

France's research agency splits up pp. 573-573

Declan Butler

The oldest pregnant mum pp. 575-575

Carina Dennis

Microbiology: The inside story pp. 578-580

Asher Mullard

Microbiology: Straight from the gut pp. 581-582

Apoorva Mandavilli

Marine microbiology: Origins of Death pp. 583-585

Nick Lane

Increasing use of stimulants warns of potential abuse pp. 586-586

James M. Swanson and Nora D. Volkow

Costa Rica's biotech project still on track for end of year pp. 586-586

Antonieta Corrales

A prime problem that even quantum computing can't solve pp. 586-586

Robert P. Bywater

Analyses support theory of stochastic regulation of fisheries pp. 586-586

Joe Horwood and John Shepherd

If you don't need change, maybe you don't need sex pp. 587-587

Flemming Ekelund and Regin Rønn

Ancient asexuals: darwinulids not exposed pp. 587-587

Koen Martens and Isa Schon

Time to break the silence around virtual-water imports pp. 587-587

Junguo Liu and H. H. G. Savenije

Retiring retirement pp. 588-590

Peter A. Lawrence

Vivisectionists strike back pp. 592-593

Andrew Read

Moralist, meet scientist pp. 593-594

Nick Bostrom

Music grown from garden weeds pp. 594-594

Colin Martin

Reimagining the Royal Institution pp. 595-595

Matt Brown

Seeing the smaller picture pp. 596-596

Martin Kemp

Hidden treasures: Bologna's Poggi Palace pp. 597-597

Alison Abbott

The neural roots of music pp. 598-599

Laurel Trainor

Hot questions of temperature bias pp. 601-602

Chris E. Forest and Richard W. Reynolds

Soothing intestinal sugars pp. 602-604

Marika C. Kullberg

Whispering sweet somethings pp. 604-605

Thea Tlsty

Sex ratios writ small pp. 605-606

Jos. J. Schall

Packings close and loose pp. 606-607

Francesco Zamponi

Sex ratio adjustment and kin discrimination in malaria parasites pp. 609-614

Sarah E. Reece, Damien R. Drew and Andy Gardner

The genomic and epidemiological dynamics of human influenza A virus pp. 615-619

Andrew Rambaut, Oliver G. Pybus, Martha I. Nelson, Cecile Viboud, Jeffery K. Taubenberger and Edward C. Holmes

A microbial symbiosis factor prevents intestinal inflammatory disease pp. 620-625

Sarkis K. Mazmanian, June L. Round and Dennis L. Kasper

An infrared ring around the magnetar SGR 1900+14 pp. 626-628

S. Wachter, E. Ramirez-Ruiz, V. V. Dwarkadas, C. Kouveliotou, J. Granot, S. K. Patel and D. Figer

A phase diagram for jammed matter pp. 629-632

Chaoming Song, Ping Wang and Hernán A. Makse

Quantum phase transition in a single-molecule quantum dot pp. 633-637

Nicolas Roch, Serge Florens, Vincent Bouchiat, Wolfgang Wernsdorfer and Franck Balestro

Anatase TiO2 single crystals with a large percentage of reactive facets pp. 638-641

Hua Gui Yang, Cheng Hua Sun, Shi Zhang Qiao, Jin Zou, Gang Liu, Sean Campbell Smith, Hui Ming Cheng and Gao Qing Lu

Snowball Earth termination by destabilization of equatorial permafrost methane clathrate pp. 642-645

Martin Kennedy, David Mrofka and Chris von der Borch

A large discontinuity in the mid-twentieth century in observed global-mean surface temperature pp. 646-649

David W. J. Thompson, John J. Kennedy, John M. Wallace and Phil D. Jones

Live birth in the Devonian period pp. 650-652

John A. Long, Kate Trinajstic, Gavin C. Young and Tim Senden

Abundance and diversity of microbial life in ocean crust pp. 653-656

Cara M. Santelli, Beth N. Orcutt, Erin Banning, Wolfgang Bach, Craig L. Moyer, Mitchell L. Sogin, Hubert Staudigel and Katrina J. Edwards

Functional genomic screen reveals genes involved in lipid-droplet formation and utilization pp. 657-661

Yi Guo, Tobias C. Walther, Meghana Rao, Nico Stuurman, Gohta Goshima, Koji Terayama, Jinny S. Wong, Ronald D. Vale, Peter Walter and Robert V. Farese

Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration pp. 662-666

Mariona Graupera, Julie Guillermet-Guibert, Lazaros C. Foukas, Li-Kun Phng, Robert J. Cain, Ashreena Salpekar, Wayne Pearce, Stephen Meek, Jaime Millan, Pedro R. Cutillas, Andrew J. H. Smith, Anne J. Ridley, Christiana Ruhrberg, Holger Gerhardt and Bart Vanhaesebroeck

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus pp. 667-671

Jens Wrammert, Kenneth Smith, Joe Miller, William A. Langley, Kenneth Kokko, Christian Larsen, Nai-Ying Zheng, Israel Mays, Lori Garman, Christina Helms, Judith James, Gillian M. Air, J. Donald Capra, Rafi Ahmed and Patrick C. Wilson

CLEC5A is critical for dengue-virus-induced lethal disease pp. 672-676

Szu-Ting Chen, Yi-Ling Lin, Ming-Ting Huang, Ming-Fang Wu, Shih-Chin Cheng, Huan-Yao Lei, Chien-Kuo Lee, Tzyy-Wen Chiou, Chi-Huey Wong and Shie-Liang Hsieh

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability pp. 677-681

Derek J. Richard, Emma Bolderson, Liza Cubeddu, Ross I. M. Wadsworth, Kienan Savage, Girdhar G. Sharma, Matthew L. Nicolette, Sergie Tsvetanov, Michael J. McIlwraith, Raj K. Pandita, Shunichi Takeda, Ronald T. Hay, Jean Gautier, Stephen C. West, Tanya T. Paull, Tej K. Pandita, Malcolm F. White and Kum Kum Khanna

HP1-β mobilization promotes chromatin changes that initiate the DNA damage response pp. 682-686

Nabieh Ayoub, Anand D. Jeyasekharan, Juan A. Bernal and Ashok R. Venkitaraman

Exploring unseen communities pp. 687-689

Nathan Blow

Contemplating the contributions of, and discrimination against, scientists who are senior citizens pp. 693-693

Gene Russo

Larry McKinney, director, Harte Research Institute for Gulf of Mexico Studies, Texas A&M University, Corpus Christi, Texas pp. 694-694

Virginia Gewin

The softer side of science pp. 694-694

Bernhard Sabel

Singapore's happiest person pp. 694-694

Amanda Goh

Morpho sanguinalis pp. 696-696

Julie Jansen

2008, volume 453, articles 7194

Journal club pp. 431-431

Andrea Manica

Polar bear numbers set to fall pp. 432-433

Rachel Courtland

Whales are on the rise pp. 433-433

Rex Dalton

Meeting urges scientists into politics pp. 434-434

Gene Russo

Sterile mosquitoes near take-off pp. 435-435

David Cyranoski

No star left behind pp. 437-437

Eric Hand

Poland tackles science like a business pp. 438-438

Quirin Schiermeier

US plans more primate research pp. 439-439

Erika Check Hayden

Eyewitness identification: Line-ups on trial pp. 442-444

Laura Spinney

Language: The language barrier pp. 446-448

Emma Marris

Standard identifier could mobilize data and free time pp. 449-450

Dave Roberts and Vishwas Chavan

Acceptance of peer review will free Italy's research slaves pp. 449-449

Ignazio R. Marino

Mimicking photosynthesis, but just the best bits pp. 449-449

A. William Rutherford and Thomas A. Moore

Name variations can hit citation rankings pp. 450-450

Biji T. Kurien

Names: dropped to avoid prejudice, now useful again pp. 450-450

Prabhu B. Patil

Open-access more harm than good in developing world pp. 450-450

Raghavendra Gadagkar

A 3D revolution in communicating science pp. 450-450

Jérôme Murienne, Alexander Ziegler and Bernhard Ruthensteiner

Security in an uncertain world pp. 451-452

Jessica Flack

Genetic medicine at the bedside pp. 452-453

Hugh Young Rienhoff

A rough guide to Titan pp. 453-454

Henry Roe

How science hit the small screen pp. 454-455

Colin Martin

Super clothes with special powers pp. 455-455

Josie Glausiusz

Lost in music pp. 456-457

David Huron

Over the rainbow pp. 459-460

John M. Lupton

Two hands for degradation pp. 460-461

Yasushi Saeki and Keiji Tanaka

Cells get in shape for a crawl pp. 461-462

Jason M. Haugh

Supernova bursts onto the scene pp. 462-463

Roger Chevalier

Snapshots of DNA repair pp. 463-465

Stephen C. Kowalczykowski

Viruses in camouflage pp. 466-467

Kirsten Sandvig and Bo van Deurs

An extremely luminous X-ray outburst at the birth of a supernova pp. 469-474

A. M. Soderberg, E. Berger, K. L. Page, P. Schady, J. Parrent, D. Pooley, X.-Y. Wang, E. O. Ofek, A. Cucchiara, A. Rau, E. Waxman, J. D. Simon, D. C.-J. Bock, P. A. Milne, M. J. Page, J. C. Barentine, S. D. Barthelmy, A. P. Beardmore, M. F. Bietenholz, P. Brown, A. Burrows, D. N. Burrows, G. Byrngelson, S. B. Cenko, P. Chandra, J. R. Cummings, D. B. Fox, A. Gal-Yam, N. Gehrels, S. Immler, M. Kasliwal, A. K. H. Kong, H. A. Krimm, S. R. Kulkarni, T. J. Maccarone, P. Mészáros, E. Nakar, P. T. O’Brien, R. A. Overzier, M. de Pasquale, J. Racusin, N. Rea and D. G. York

Mechanism of shape determination in motile cells pp. 475-480

Kinneret Keren, Zachary Pincus, Greg M. Allen, Erin L. Barnhart, Gerard Marriott, Alex Mogilner and Julie A. Theriot

Proteasome subunit Rpn13 is a novel ubiquitin receptor pp. 481-488

Koraljka Husnjak, Suzanne Elsasser, Naixia Zhang, Xiang Chen, Leah Randles, Yuan Shi, Kay Hofmann, Kylie J. Walters, Daniel Finley and Ivan Dikic

Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures pp. 489-494

Zhucheng Chen, Haijuan Yang and Nikola P. Pavletich

A Lévy flight for light pp. 495-498

Pierre Barthelemy, Jacopo Bertolotti and Diederik S. Wiersma

Gelation of particles with short-range attraction pp. 499-503

Peter J. Lu, Emanuela Zaccarelli, Fabio Ciulla, Andrew B. Schofield, Francesco Sciortino and David A. Weitz

Triple oxygen isotope evidence for elevated CO2 levels after a Neoproterozoic glaciation pp. 504-506

Huiming Bao, J. R. Lyons and Chuanming Zhou

Seismogenic lavas and explosive eruption forecasting pp. 507-510

Y. Lavallée, P. G. Meredith, D. B. Dingwell, K.-U. Hess, J. Wassermann, B. Cordonnier, A. Gerik and J. H. Kruhl

Evidence for seismogenic fracture of silicic magma pp. 511-514

Hugh Tuffen, Rosanna Smith and Peter R. Sammonds

A stem batrachian from the Early Permian of Texas and the origin of frogs and salamanders pp. 515-518

Jason S. Anderson, Robert R. Reisz, Diane Scott, Nadia B. Fröbisch and Stuart S. Sumida

The ground state of embryonic stem cell self-renewal pp. 519-523

Qi-Long Ying, Jason Wray, Jennifer Nichols, Laura Batlle-Morera, Bradley Doble, James Woodgett, Philip Cohen and Austin Smith

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population pp. 524-528

Lei Yang, Mark H. Soonpaa, Eric D. Adler, Torsten K. Roepke, Steven J. Kattman, Marion Kennedy, Els Henckaerts, Kristina Bonham, Geoffrey W. Abbott, R. Michael Linden, Loren J. Field and Gordon M. Keller

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation pp. 529-533

Wei Guo, Joseph L. Lasky, Chun-Ju Chang, Sherly Mosessian, Xiaoman Lewis, Yun Xiao, Jennifer E. Yeh, James Y. Chen, M. Luisa Iruela-Arispe, Marileila Varella-Garcia and Hong Wu

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes pp. 534-538

Oliver H. Tam, Alexei A. Aravin, Paula Stein, Angelique Girard, Elizabeth P. Murchison, Sihem Cheloufi, Emily Hodges, Martin Anger, Ravi Sachidanandam, Richard M. Schultz and Gregory J. Hannon

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes pp. 539-543

Toshiaki Watanabe, Yasushi Totoki, Atsushi Toyoda, Masahiro Kaneda, Satomi Kuramochi-Miyagawa, Yayoi Obata, Hatsune Chiba, Yuji Kohara, Tomohiro Kono, Toru Nakano, M. Azim Surani, Yoshiyuki Sakaki and Hiroyuki Sasaki

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells pp. 544-547

Hannah H. Chang, Martin Hemberg, Mauricio Barahona, Donald E. Ingber and Sui Huang

Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction pp. 548-552

Patrick Schreiner, Xiang Chen, Koraljka Husnjak, Leah Randles, Naixia Zhang, Suzanne Elsasser, Daniel Finley, Ivan Dikic, Kylie J. Walters and Michael Groll

A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi pp. 553-556

Anastasios D. Tsaousis, Edmund R. S. Kunji, Alina V. Goldberg, John M. Lucocq, Robert P. Hirt and T. Martin Embley

Energy-related jobs could be on the rise for years to come pp. 557-557

Paul Smaglik

Westernizing Eastern-bloc science pp. 558-559

Quirin Schiermeier

Frank Torti, chief scientist, US Food and Drug Administration pp. 560-560

Virginia Gewin

Upping student numbers and diversity pp. 560-560

Virginia Gewin

An impassive observation pp. 560-560

Aliza le Roux

The Neanderthal correlation pp. 562-562

Jeff Hecht

2008, volume 453, articles 7193

Journal club pp. 261-261

Carl Bergstrom

Raking through sludge exposes a stink pp. 262-263

Jeff Tollefson

German universities bow to public pressure over GM crops pp. 263-263

Quirin Schiermeier

Flights of green fancy pp. 264-265

Katharine Sanderson

Charged clouds pp. 267-267

Geoff Brumfiel

A side-splitting tale pp. 267-267

Anna Petherick

They say they want a revolution pp. 268-269

Olive Heffernan

Chemistry: Designer debacle pp. 275-278

Erika Check Hayden

Deforestation: call for justice, not militarization pp. 280-280

Samuel J. Spiegel

Deforestation: damage from dams adds to emissions pp. 280-280

André Frainer Barbosa

Hype around nanotubes creates unrealistic hopes pp. 280-280

Kostas Kostarelos, Alberto Bianco and Maurizio Prato

A case of genetic counselling for Dr Watson pp. 281-281

Myra I. Roche

The public needs to know social benefits of vaccination pp. 281-281

Anthony Robbins

Public support never has guaranteed good work pp. 281-281

Neville W. Goodman

Big problems, big decisions pp. 282-283

Michael Sargent

Enshrining the right to live or die pp. 284-285

Emily Jackson

Charting the water's edge pp. 285-286

Deborah Jean Warner

Changing perceptions of light pp. 286-286

Christopher Turner

The evolution of music pp. 287-288

Josh McDermott

25 years of HIV pp. 289-290

Anthony S. Fauci

Windows on the greenhouse pp. 291-292

Ed Brook

The rhodopsin story continued pp. 292-293

Gebhard F. X. Schertler

An integrated light circuit pp. 294-295

Paul G. Kwiat

Deadly combination pp. 295-296

Stefan H. E. Kaufmann

Attributing cause and effect pp. 296-297

Francis Zwiers and Gabriele Hegerl

Polaritronics in view pp. 297-298

Benoît Deveaud-Plédran

In their neighbour's shadow pp. 298-299

Jir̆í Friml and Michael Sauer

Edward N. Lorenz (1917–2008) pp. 300-300

Edward Ott

Regenerative medicine pp. 301-301

Natalie DeWitt

Regenerative medicine and human models of human disease pp. 302-305

Kenneth R. Chien

Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal pp. 306-313

Leonard I. Zon

Wound repair and regeneration pp. 314-321

Geoffrey C. Gurtner, Sabine Werner, Yann Barrandon and Michael T. Longaker

Stem-cell-based therapy and lessons from the heart pp. 322-329

Robert Passier, Linda W. van Laake and Christine L. Mummery

Tolerance strategies for stem-cell-based therapies pp. 330-337

Ann P. Chidgey, Daniel Layton, Alan Trounson and Richard L. Boyd

A chemical approach to stem-cell biology and regenerative medicine pp. 338-344

Yue Xu, Yan Shi and Sheng Ding

Imaging stem-cell-driven regeneration in mammals pp. 345-351

Timm Schroeder

Attributing physical and biological impacts to anthropogenic climate change pp. 353-357

Cynthia Rosenzweig, David Karoly, Marta Vicarelli, Peter Neofotis, Qigang Wu, Gino Casassa, Annette Menzel, Terry L. Root, Nicole Estrella, Bernard Seguin, Piotr Tryjanowski, Chunzhen Liu, Samuel Rawlins and Anton Imeson

Nucleosome organization in the Drosophila genome pp. 358-362

Travis N. Mavrich, Cizhong Jiang, Ilya P. Ioshikhes, Xiaoyong Li, Bryan J. Venters, Sara J. Zanton, Lynn P. Tomsho, Ji Qi, Robert L. Glaser, Stephan C. Schuster, David S. Gilmour, Istvan Albert and B. Franklin Pugh

Crystal structure of squid rhodopsin pp. 363-367

Midori Murakami and Tsutomu Kouyama

True polar wander on Europa from global-scale small-circle depressions pp. 368-371

Paul Schenk, Isamu Matsuyama and Francis Nimmo

A GaAs polariton light-emitting diode operating near room temperature pp. 372-375

S. I. Tsintzos, N. T. Pelekanos, G. Konstantinidis, Z. Hatzopoulos and P. G. Savvidis

Superconductivity at 43 K in an iron-based layered compound LaO1-xFxFeAs pp. 376-378

Hiroki Takahashi, Kazumi Igawa, Kazunobu Arii, Yoichi Kamihara, Masahiro Hirano and Hideo Hosono

High-resolution carbon dioxide concentration record 650,000–800,000 years before present pp. 379-382

Dieter Lüthi, Martine Le Floch, Bernhard Bereiter, Thomas Blunier, Jean-Marc Barnola, Urs Siegenthaler, Dominique Raynaud, Jean Jouzel, Hubertus Fischer, Kenji Kawamura and Thomas F. Stocker

Orbital and millennial-scale features of atmospheric CH4 over the past 800,000 years pp. 383-386

Laetitia Loulergue, Adrian Schilt, Renato Spahni, Valérie Masson-Delmotte, Thomas Blunier, Bénédicte Lemieux, Jean-Marc Barnola, Dominique Raynaud, Thomas F. Stocker and Jérôme Chappellaz

Chemical compass model of avian magnetoreception pp. 387-390

Kiminori Maeda, Kevin B. Henbest, Filippo Cintolesi, Ilya Kuprov, Christopher T. Rodgers, Paul A. Liddell, Devens Gust, Christiane R. Timmel and P. J. Hore

Evolution of metal hyperaccumulation required cis-regulatory changes and triplication of HMA4 pp. 391-395

Marc Hanikenne, Ina N. Talke, Michael J. Haydon, Christa Lanz, Andrea Nolte, Patrick Motte, Juergen Kroymann, Detlef Weigel and Ute Krämer

Human metabolic phenotype diversity and its association with diet and blood pressure pp. 396-400

Elaine Holmes, Ruey Leng Loo, Jeremiah Stamler, Magda Bictash, Ivan K. S. Yap, Queenie Chan, Tim Ebbels, Maria De Iorio, Ian J. Brown, Kirill A. Veselkov, Martha L. Daviglus, Hugo Kesteloot, Hirotsugu Ueshima, Liancheng Zhao, Jeremy K. Nicholson and Paul Elliott

Genetic evidence that FGFs have an instructive role in limb proximal–distal patterning pp. 401-405

Francesca V. Mariani, Christina P. Ahn and Gail R. Martin

Free choice activates a decision circuit between frontal and parietal cortex pp. 406-409

Bijan Pesaran, Matthew J. Nelson and Richard A. Andersen

Vascular normalization in Rgs5-deficient tumours promotes immune destruction pp. 410-414

Juliana Hamzah, Manfred Jugold, Fabian Kiessling, Paul Rigby, Mitali Manzur, Hugo H. Marti, Tamer Rabie, Sylvia Kaden, Hermann-Josef Gröne, Günter J. Hämmerling, Bernd Arnold and Ruth Ganss

3.88 Å structure of cytoplasmic polyhedrosis virus by cryo-electron microscopy pp. 415-419

Xuekui Yu, Lei Jin and Z. Hong Zhou

Aspiring interdisciplinarians should think beyond academia pp. 421-421

Gene Russo

Assembly work pp. 422-423

Brian Vastag

Craig Hogan, director, Center for Particle Astrophysics, Fermi National Accelerator Laboratory and professor of astronomy and astrophysics, University of Chicago, Illinois pp. 424-424

Virginia Gewin

The postdoc interview pp. 424-424

Kryste Ferguson and Ivonne Vidal Pizarro

Judging me, judging you pp. 424-424

Jon Yearsley

Sanctity pp. 426-426

Heather Bradshaw

2008, volume 453, articles 7192

Journal club pp. 137-137

François Balloux

Top billing for platypus at end of evolution tree pp. 138-139

Susan Brown

Chemists spin a web of data pp. 139-139

Geoff Brumfiel

Medical schools swap pigs for plastic pp. 140-141

Meredith Wadman

Phoenix descending pp. 142-142

Eric Hand

Research revolution? pp. 143-143

Declan Butler

Earth science: Harnessing the hum pp. 146-148

Rachel Courtland

Cell biology: The cellular hullabaloo pp. 150-153

Helen Pearson

Long-range energy forecasts are no more than fairy tales pp. 154-154

Vaclav Smil

Energy assumptions were reasonable at the time, but not now pp. 154-155

Christopher B. Field

Future scenarios for emissions need continual adjustment pp. 155-155

Richard G. Richels, Richard Tol and Gary Yohe

Climate policies will stimulate technology development pp. 155-155

Ottmar Edenhofer, Bill Hare, Brigitte Knopf and Gunnar Luderer

IPCC's climate-policy assumptions were justified pp. 155-155

Joseph Romm

Not so amateur pp. 156-156

Owen Gingerich

How brains develop pp. 157-157

Bruce M. Hood

Learning from climates past pp. 158-158

Chris Turney

Mountains into molehills pp. 158-158

Emma Marris

Saving art in situ pp. 159-159

Giacomo Chiari

Facing the music pp. 160-162

Philip Ball

Music of the stratospheres pp. 163-164

Timothy E. Dowling

Old enzymes, new tricks pp. 165-166

Giovanna Ghirlanda

Chance match pp. 166-167

Robert M. Westervelt

Stopping the rot pp. 167-168

Philip C. E. Stamp

What's your fat-cell allowance? pp. 169-169

Sadaf Shadan

An HIV secret uncovered pp. 169-170

Eddy Arnold and Stefan G. Sarafianos

Supramolecular polymers pp. 171-173

Tom F. A. de Greef and E. W. Meijer

Dynamic binding orientations direct activity of HIV reverse transcriptase pp. 184-189

Elio A. Abbondanzieri, Gregory Bokinsky, Jason W. Rausch, Jennifer X. Zhang, Stuart F. J. Le Grice and Xiaowei Zhuang

Kemp elimination catalysts by computational enzyme design pp. 190-195

Daniela Röthlisberger, Olga Khersonsky, Andrew M. Wollacott, Lin Jiang, Jason DeChancie, Jamie Betker, Jasmine L. Gallaher, Eric A. Althoff, Alexandre Zanghellini, Orly Dym, Shira Albeck, Kendall N. Houk, Dan S. Tawfik and David Baker

Semi-annual oscillations in Saturn’s low-latitude stratospheric temperatures pp. 196-199

Glenn S. Orton, Padma A. Yanamandra-Fisher, Brendan M. Fisher, A. James Friedson, Paul D. Parrish, Jesse F. Nelson, Amber Swenson Bauermeister, Leigh Fletcher, Daniel Y. Gezari, Frank Varosi, Alan T. Tokunaga, John Caldwell, Kevin H. Baines, Joseph L. Hora, Michael E. Ressler, Takuya Fujiyoshi, Tetsuharu Fuse, Hagop Hagopian, Terry Z. Martin, Jay T. Bergstralh, Carly Howett, William F. Hoffmann, Lynne K. Deutsch, Jeffrey E. Van Cleve, Eldar Noe, Joseph D. Adams, Marc Kassis and Eric Tollestrup

An equatorial oscillation in Saturn’s middle atmosphere pp. 200-202

T. Fouchet, S. Guerlet, D. F. Strobel, A. A. Simon-Miller, B. Bézard and F. M. Flasar

Quantum oscillations in a molecular magnet pp. 203-206

S. Bertaina, S. Gambarelli, T. Mitra, B. Tsukerblat, A. Müller and B. Barbara

Colossal cages in zeolitic imidazolate frameworks as selective carbon dioxide reservoirs pp. 207-211

Bo Wang, Adrien P. Côté, Hiroyasu Furukawa, Michael O’Keeffe and Omar M. Yaghi

Increasing risk of Amazonian drought due to decreasing aerosol pollution pp. 212-215

Peter M. Cox, Phil P. Harris, Chris Huntingford, Richard A. Betts, Matthew Collins, Chris D. Jones, Tim E. Jupp, José A. Marengo and Carlos A. Nobre

Scale effects and human impact on the elevational species richness gradients pp. 216-219

D. Nogués-Bravo, M. B. Araújo, T. Romdal and C. Rahbek

Neutral metacommunity models predict fish diversity patterns in Mississippi–Missouri basin pp. 220-222

Rachata Muneepeerakul, Enrico Bertuzzo, Heather J. Lynch, William F. Fagan, Andrea Rinaldo and Ignacio Rodriguez-Iturbe

REST maintains self-renewal and pluripotency of embryonic stem cells pp. 223-227

Sanjay K. Singh, Mohamedi N. Kagalwala, Jan Parker-Thornburg, Henry Adams and Sadhan Majumder

Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors pp. 228-232

Omobolaji O. Akala, In-Kyung Park, Dalong Qian, Michael Pihalja, Michael W. Becker and Michael F. Clarke

Discrete fixed-resolution representations in visual working memory pp. 233-235

Weiwei Zhang and Steven J. Luck

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function pp. 236-240

Liang Zhou, Jared E. Lopes, Mark M. W. Chong, Ivaylo I. Ivanov, Roy Min, Gabriel D. Victora, Yuelei Shen, Jianguang Du, Yuri P. Rubtsov, Alexander Y. Rudensky, Steven F. Ziegler and Dan R. Littman

Imaging of Rab5 activity identifies essential regulators for phagosome maturation pp. 241-245

Masahiro Kitano, Michio Nakaya, Takeshi Nakamura, Shigekazu Nagata and Michiyuki Matsuda

Chromatin decouples promoter threshold from dynamic range pp. 246-250

Felix H. Lam, David J. Steger and Erin K. O’Shea

Postdocs need a set of defined, widely endorsed core competencies. Or do they? pp. 251-251

Gene Russo

Toronto rising pp. 252-253

Kurt Kleiner

Karin Lochte, director, Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Germany pp. 254-254

Virginia Gewin

Animal assets in academia pp. 254-254

Virginia Gewin

Going with your gut pp. 254-254

Zachary Lippman

The icosahedral anaster pp. 256-256

John P. Boyd

2008, volume 453, articles 7191

Journal club pp. 5-5

Kristi Anseth

Doctors accused of doing illegal stem-cell trials pp. 6-7

Alison Abbott

US ocean-research projects in dire economic straits pp. 7-7

Rex Dalton

Food crisis spurs research spending pp. 8-8

Declan Butler

Genetics bill cruises through Senate pp. 9-9

Meredith Wadman

If you go down to the woods today pp. 11-11

Eric Hand

Programs promise to end PDF paper-chase pp. 12-12

Rachel Courtland

Sediment cores reveal Antarctica's warmer past pp. 13-13

Quirin Schiermeier

Demonstrably wrong pp. 16-16

David Goldston

Stem cells: The 3-billion-dollar question pp. 18-21

Erika Check Hayden

Physics: Quantum all the way pp. 22-25

Philip Ball

Spain should implement a model that's known to work pp. 26-27

Rodrigo J. Carbajo, José Luis Neira and Rosa Farràs

Biopiracy rules hinder conservation efforts pp. 26-26

Valentí Rull and Teresa Vegas-Vilarrúbia

Biopiracy: conservationists have to rebuild lost trust pp. 26-26

Mariana M. Vale, Maria Alice Alves and Stuart L. Pimm

Spain: leading role of scientists is heartening pp. 27-27

Pere Puigdomènech

Darwin–Wallace principle of natural selection pp. 27-27

U. Kutschera

The status of science in Muslim nations pp. 27-27

K. Razi Naqvi

Making the grade pp. 28-30

Hal Salzman and Lindsay Lowell

Science teaching must evolve pp. 31-32

Andrew Moore

Mix and mash-up pp. 33-34

Marc Weidenbaum

Exemplary epidemiology pp. 34-34

Mark Woolhouse

Measure for measure pp. 35-35

John D. Barrow

Changing expressions pp. 36-36

Laura Spinney

Etching the artist's mind pp. 36-36

Colin Martin

The Impressionists' bible pp. 37-37

Martin Kemp

When business became biology's plague pp. 38-38

Thomas Häusler

Lifting the fog from the north pp. 39-39

Maximilian Schlosshauer

Hidden female talent pp. 41-42

Jai Y. Yu and Barry J. Dickson

The fourth element pp. 42-43

James M. Tour and Tao He

Natural ups and downs pp. 43-45

Richard Wood

The squeeze goes on pp. 45-46

Eugene S. Polzik

T cells hang in the balance pp. 46-47

Emily A. Stevens and Christopher A. Bradfield

Teasing out the missing links pp. 47-48

Sid Redner

Rays from the dark pp. 48-49

Rainer Plaga

John Wheeler (1911–2008) pp. 50-50

P. James E. Peebles and William G. Unruh

Rapid leukocyte migration by integrin-independent flowing and squeezing pp. 51-55

Tim Lämmermann, Bernhard L. Bader, Susan J. Monkley, Tim Worbs, Roland Wedlich-Söldner, Karin Hirsch, Markus Keller, Reinhold Förster, David R. Critchley, Reinhard Fässler and Michael Sixt

Mapping and sequencing of structural variation from eight human genomes pp. 56-64

Jeffrey M. Kidd, Gregory M. Cooper, William F. Donahue, Hillary S. Hayden, Nick Sampas, Tina Graves, Nancy Hansen, Brian Teague, Can Alkan, Francesca Antonacci, Eric Haugen, Troy Zerr, N. Alice Yamada, Peter Tsang, Tera L. Newman, Eray Tüzün, Ze Cheng, Heather M. Ebling, Nadeem Tusneem, Robert David, Will Gillett, Karen A. Phelps, Molly Weaver, David Saranga, Adrianne Brand, Wei Tao, Erik Gustafson, Kevin McKernan, Lin Chen, Maika Malig, Joshua D. Smith, Joshua M. Korn, Steven A. McCarroll, David A. Altshuler, Daniel A. Peiffer, Michael Dorschner, John Stamatoyannopoulos, David Schwartz, Deborah A. Nickerson, James C. Mullikin, Richard K. Wilson, Laurakay Bruhn, Maynard V. Olson, Rajinder Kaul, Douglas R. Smith and Evan E. Eichler

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor pp. 65-71

Francisco J. Quintana, Alexandre S. Basso, Antonio H. Iglesias, Thomas Korn, Mauricio F. Farez, Estelle Bettelli, Mario Caccamo, Mohamed Oukka and Howard L. Weiner

The sculpting of Jupiter’s gossamer rings by its shadow pp. 72-75

Douglas P. Hamilton and Harald Krüger

Phase-slip-induced dissipation in an atomic Bose–Hubbard system pp. 76-79

D. McKay, M. White, M. Pasienski and B. DeMarco

The missing memristor found pp. 80-83

Dmitri B. Strukov, Gregory S. Snider, Duncan R. Stewart and R. Stanley Williams

Advancing decadal-scale climate prediction in the North Atlantic sector pp. 84-88

N. S. Keenlyside, M. Latif, J. Jungclaus, L. Kornblueh and E. Roeckner

Origin of a ‘Southern Hemisphere’ geochemical signature in the Arctic upper mantle pp. 89-93

Steven L. Goldstein, Gad Soffer, Charles H. Langmuir, Kerstin A. Lehnert, David W. Graham and Peter J. Michael

Hydatellaceae are water lilies with gymnospermous tendencies pp. 94-97

William E. Friedman

Hierarchical structure and the prediction of missing links in networks pp. 98-101

Aaron Clauset, Cristopher Moore and M. E. J. Newman

Melanopsin cells are the principal conduits for rod–cone input to non-image-forming vision pp. 102-105

Ali D. Güler, Jennifer L. Ecker, Gurprit S. Lall, Shafiqul Haq, Cara M. Altimus, Hsi-Wen Liao, Alun R. Barnard, Hugh Cahill, Tudor C. Badea, Haiqing Zhao, Mark W. Hankins, David M. Berson, Robert J. Lucas, King-Wai Yau and Samer Hattar

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins pp. 106-109

Marc Veldhoen, Keiji Hirota, Astrid M. Westendorf, Jan Buer, Laure Dumoutier, Jean-Christophe Renauld and Brigitta Stockinger

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros pp. 110-114

Charles G. Mullighan, Christopher B. Miller, Ina Radtke, Letha A. Phillips, James Dalton, Jing Ma, Deborah White, Timothy P. Hughes, Michelle M. Le Beau, Ching-Hon Pui, Mary V. Relling, Sheila A. Shurtleff and James R. Downing

Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions pp. 115-119

Stavroula Mili, Konstadinos Moissoglu and Ian G. Macara

Life without RNase P pp. 120-123

Lennart Randau, Imke Schröder and Dieter Söll

Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS pp. 124-127

Raz Zarivach, Wanyin Deng, Marija Vuckovic, Heather B. Felise, Hai V. Nguyen, Samuel I. Miller, B. Brett Finlay and Natalie C. J. Strynadka

Erratum: Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila pp. 128-128

Cathy Haag-Liautard, Mark Dorris, Xulio Maside, Steven Macaskill, Daniel L. Halligan, David Houle, Brian Charlesworth and Peter D. Keightley

US National Postdoctoral Association campaigns for stipend boost pp. 129-129

Gene Russo

Eaton E. Lattman, chief executive and executive director of the Hauptman-Woodward Medical Research Institute, Buffalo, New York pp. 130-130

Virginia Gewin

Crossing borders pp. 130-130

Paul Smaglik

Meeting our targets pp. 130-130

Amanda Goh

Build your own time machine pp. 132-132

Igor Teper