TRIM5 does double duty

Christopher Aiken () and Sebastian Joyce
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Christopher Aiken: Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
Sebastian Joyce: Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.

Nature, 2011, vol. 472, issue 7343, 305-306

Abstract: TRIM5 proteins limit retroviral infection by targeting the viral coat. It now seems that these proteins can also serve as pattern-recognition receptors, which initiate cellular innate immune responses. See Letter p.361

Date: 2011
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DOI: 10.1038/472305a

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