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2010, volume 468, articles 7327

Nutrigenomics pp. S1-S1

Michelle Grayson

Interdisciplinary research: Big science at the table pp. S2-S4

Lucas Laursen

Development: Mother's milk: A rich opportunity pp. S5-S7

Anna Petherick

Evolution: The first supper pp. S8-S9

Michael Eisenstein

Health: Edible advice pp. S10-S12

Farooq Ahmed

Diversity: Of beans and genes pp. S13-S15

Michael Eisenstein

History: The changing notion of food pp. S16-S17

Ned Stafford

Taste: More than meets the mouth pp. S18-S19

Michael Eisenstein

Epigenetics: Tales of adversity pp. S20-S20

Farooq Ahmed

Technology: A flavour of the future pp. S21-S22

Arran Frood

Save university arts from the bean counters pp. 1003-1003

Gregory Petsko

Integrity policy unveiled at last pp. 1009-1010

Eugenie Samuel Reich

UK science faces facilities freeze pp. 1010-1010

Geoff Brumfiel and Natasha Gilbert

Fossil genome reveals ancestral link pp. 1012-1012

Ewen Callaway

Deep lab denied funding pp. 1013-1013

Eugenie Samuel Reich

2010: The year in which … pp. 1014-1016

Adam Mann

Newsmaker of the year: In the eye of the storm pp. 1024-1028

Richard Monastersky

Keep it complex pp. 1029-1031

Andy Stirling

Stand up for science pp. 1032-1033

Nancy Baron

Conservation: After the ice pp. 1034-1035

Yvon Le Maho

In retrospect: Pauling's primer pp. 1036-1036

Philip Ball

Communication: Mapping science pp. 1037-1037

Ben Shneiderman

History: Science fit for a king pp. 1038-1038

Laura Spinney

Q&A: Impossible thoughts pp. 1039-1039

Jascha Hoffman

No crisis in supply of peer reviewers pp. 1041-1041

Tim Vines, Loren Rieseberg and Harry Smith

Brazil's renewable energy success pp. 1041-1041

Allan Kardec Duailibe

Economic growth: a gross measure pp. 1041-1041

David Fisk

Misreporting: hippo stories off-target pp. 1041-1041

P. J. N. de Bruyn

Brian Marsden (1937–2010) pp. 1042-1042

Owen Gingerich

Shadows of early migrations pp. 1044-1045

Carlos D. Bustamante and Brenna M. Henn

Electrons spin in the field pp. 1045-1046

David J. Reilly

Proteins in dynamic equilibrium pp. 1046-1048

Pau Bernadó and Martin Blackledge

A giant surprise pp. 1048-1049

Laird Close

A gene for impulsivity pp. 1049-1050

John R. Kelsoe

Reader's block pp. 1050-1051

Sean D. Taverna and PhiliP A. Cole

Genetic history of an archaic hominin group from Denisova Cave in Siberia pp. 1053-1060

David Reich, Richard E. Green, Martin Kircher, Johannes Krause, Nick Patterson, Eric Y. Durand, Bence Viola, Adrian W. Briggs, Udo Stenzel, Philip L. F. Johnson, Tomislav Maricic, Jeffrey M. Good, Tomas Marques-Bonet, Can Alkan, Qiaomei Fu, Swapan Mallick, Heng Li, Matthias Meyer, Evan E. Eichler, Mark Stoneking, Michael Richards, Sahra Talamo, Michael V. Shunkov, Anatoli P. Derevianko, Jean-Jacques Hublin, Janet Kelso, Montgomery Slatkin and Svante Pääbo

A population-specific HTR2B stop codon predisposes to severe impulsivity pp. 1061-1066

Laura Bevilacqua, Stéphane Doly, Jaakko Kaprio, Qiaoping Yuan, Roope Tikkanen, Tiina Paunio, Zhifeng Zhou, Juho Wedenoja, Luc Maroteaux, Silvina Diaz, Arnaud Belmer, Colin A. Hodgkinson, Liliana Dell’Osso, Jaana Suvisaari, Emil Coccaro, Richard J. Rose, Leena Peltonen, Matti Virkkunen and David Goldman

Selective inhibition of BET bromodomains pp. 1067-1073

Panagis Filippakopoulos, Jun Qi, Sarah Picaud, Yao Shen, William B. Smith, Oleg Fedorov, Elizabeth M. Morse, Tracey Keates, Tyler T. Hickman, Ildiko Felletar, Martin Philpott, Shonagh Munro, Michael R. McKeown, Yuchuan Wang, Amanda L. Christie, Nathan West, Michael J. Cameron, Brian Schwartz, Tom D. Heightman, Nicholas La Thangue, Christopher A. French, Olaf Wiest, Andrew L. Kung, Stefan Knapp and James E. Bradner

Driving the cell cycle with a minimal CDK control network pp. 1074-1079

Damien Coudreuse and Paul Nurse

Images of a fourth planet orbiting HR 8799 pp. 1080-1083

Christian Marois, B. Zuckerman, Quinn M. Konopacky, Bruce Macintosh and Travis Barman

Spin–orbit qubit in a semiconductor nanowire pp. 1084-1087

S. Nadj-Perge, S. M. Frolov, E. P. A. M. Bakkers and L. P. Kouwenhoven

Atom-by-atom spectroscopy at graphene edge pp. 1088-1090

Kazu Suenaga and Masanori Koshino

Mantle superplasticity and its self-made demise pp. 1091-1094

Takehiko Hiraga, Tomonori Miyazaki, Miki Tasaka and Hidehiro Yoshida

Subtypes of medulloblastoma have distinct developmental origins pp. 1095-1099

Paul Gibson, Yiai Tong, Giles Robinson, Margaret C. Thompson, D. Spencer Currle, Christopher Eden, Tanya A. Kranenburg, Twala Hogg, Helen Poppleton, Julie Martin, David Finkelstein, Stanley Pounds, Aaron Weiss, Zoltan Patay, Matthew Scoggins, Robert Ogg, Yanxin Pei, Zeng-Jie Yang, Sonja Brun, Youngsoo Lee, Frederique Zindy, Janet C. Lindsey, Makoto M. Taketo, Frederick A. Boop, Robert A. Sanford, Amar Gajjar, Steven C. Clifford, Martine F. Roussel, Peter J. McKinnon, David H. Gutmann, David W. Ellison, Robert Wechsler-Reya and Richard J. Gilbertson

mTORC1 controls fasting-induced ketogenesis and its modulation by ageing pp. 1100-1104

Shomit Sengupta, Timothy R. Peterson, Mathieu Laplante, Stephanie Oh and David M. Sabatini

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8 pp. 1105-1109

Avnish Kapoor, Matthew S. Goldberg, Lara K. Cumberland, Kajan Ratnakumar, Miguel F. Segura, Patrick O. Emanuel, Silvia Menendez, Chiara Vardabasso, Gary LeRoy, Claudia I. Vidal, David Polsky, Iman Osman, Benjamin A. Garcia, Eva Hernando and Emily Bernstein

Planar polarized actomyosin contractile flows control epithelial junction remodelling pp. 1110-1114

Matteo Rauzi, Pierre-François Lenne and Thomas Lecuit

S-glutathionylation uncouples eNOS and regulates its cellular and vascular function pp. 1115-1118

Chun-An Chen, Tse-Yao Wang, Saradhadevi Varadharaj, Levy A. Reyes, Craig Hemann, M. A. Hassan Talukder, Yeong-Renn Chen, Lawrence J. Druhan and Jay L. Zweier

Suppression of inflammation by a synthetic histone mimic pp. 1119-1123

Edwige Nicodeme, Kate L. Jeffrey, Uwe Schaefer, Soren Beinke, Scott Dewell, Chun-wa Chung, Rohit Chandwani, Ivan Marazzi, Paul Wilson, Hervé Coste, Julia White, Jorge Kirilovsky, Charles M. Rice, Jose M. Lora, Rab K. Prinjha, Kevin Lee and Alexander Tarakhovsky

Transcriptional activation of polycomb-repressed genes by ZRF1 pp. 1124-1128

Holger Richly, Luciana Rocha-Viegas, Joana Domingues Ribeiro, Santiago Demajo, Gunes Gundem, Nuria Lopez-Bigas, Tekeya Nakagawa, Sabine Rospert, Takashi Ito and Luciano Di Croce

Neurotransmitter/sodium symporter orthologue LeuT has a single high-affinity substrate site pp. 1129-1132

Chayne L. Piscitelli, Harini Krishnamurthy and Eric Gouaux

Middle East: The growth of a desert jewel pp. 1133-1135

Waleed Al-Shobakky

Employment trends: Drawn to academia pp. 1135-1135

Karen Kaplan

Recursion1 pp. 1138-1138

Simon Quellen Field

2010, volume 468, articles 7326

Was the universal common ancestry proved? pp. E9-E9

Takahiro Yonezawa and Masami Hasegawa

Theobald reply pp. E10-E10

D. L. Theobald

Drug development needs a new brand of science pp. 869-869

Garret FitzGerald

Last-minute deal saves climate talks pp. 875-876

Jeff Tollefson

No black holes, but extra time at LHC pp. 876-876

Geoff Brumfiel

The bridge between lab and clinic pp. 877-877

Meredith Wadman

Slim spoils for obesity drugs pp. 878-878

Heidi Ledford

Germans cook up liver project pp. 879-879

Alison Abbott

The rise of the genome bloggers pp. 880-881

Ewen Callaway

Developers call for handy lab aids pp. 881-881

Declan Butler

Venus miss is a setback for Japanese programme pp. 882-882

David Cyranoski

Epidemiology: Fear in the dust pp. 884-885

Brendan Maher

Plant biology: Growth industry pp. 886-888

Alison Abbott

Build life to understand it pp. 889-890

Michael Elowitz and Wendell A. Lim

The Arctic melting pot pp. 891-891

Brendan P. Kelly, Andrew Whiteley and David Tallmon

Innovation: Fighting monopolies pp. 892-893

Li Gong

Ecology: The mystery of eels pp. 894-895

Kim Aarestrup

Conservation: Biodiversity as a bonus prize pp. 895-895

Emma Marris

Neuroscience: Opiates for the people pp. 896-896

W. F. Bynum

Economic growth: indicators not targets pp. 897-897

Konrad Hinsen

Economic growth: enough is enough pp. 897-897

Daniel W. O'Neill

Coordinate green growth pp. 897-897

Floortje Alkemade and Marko Hekkert

A slip in the date of DNA's discovery pp. 897-897

Ralf Dahm

Allan Sandage (1926–2010) pp. 898-898

Gustav A. Tammann

Feel the light pp. 900-901

Paul A. Garrity

A strange ménage à trois pp. 901-902

Sidney van den Bergh

How melanomas bypass new therapy pp. 902-903

David Solit and Charles L. Sawyers

Recipe for making Saturn's rings pp. 903-905

Aurélien Crida and Sébastien Charnoz

The prospects for polar bears pp. 905-906

Andrew E. Derocher

Pleated crystals pp. 906-907

Francesco Stellacci and Andreas Mortensen

Angelman syndrome connections pp. 907-908

Peter Scheiffele and Asim A. Beg

Model's reputation restored pp. 908-909

Mark A. de Vries and Andrew Harrison

Emerging properties of animal gene regulatory networks pp. 911-920

Eric H. Davidson

Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall pp. 921-926

Yang Xiang, Quan Yuan, Nina Vogt, Loren L. Looger, Lily Yeh Jan and Yuh Nung Jan

TRIM24 links a non-canonical histone signature to breast cancer pp. 927-932

Wen-Wei Tsai, Zhanxin Wang, Teresa T. Yiu, Kadir C. Akdemir, Weiya Xia, Stefan Winter, Cheng-Yu Tsai, Xiaobing Shi, Dirk Schwarzer, William Plunkett, Bruce Aronow, Or Gozani, Wolfgang Fischle, Mien-Chie Hung, Dinshaw J. Patel and Michelle Craig Barton

CRTC3 links catecholamine signalling to energy balance pp. 933-939

Youngsup Song, Judith Altarejos, Mark O. Goodarzi, Hiroshi Inoue, Xiuqing Guo, Rebecca Berdeaux, Jeong-Ho Kim, Jason Goode, Motoyuki Igata, Jose C. Paz, Meghan F. Hogan, Pankaj K. Singh, Naomi Goebel, Lili Vera, Nina Miller, Jinrui Cui, Michelle R. Jones, Consortium Charge, Consortium Giant, Yii- Der I. Chen, Kent D. Taylor, Willa A. Hsueh, Jerome I. Rotter and Marc Montminy

A substantial population of low-mass stars in luminous elliptical galaxies pp. 940-942

Pieter G. van Dokkum and Charlie Conroy

Origin of Saturn’s rings and inner moons by mass removal from a lost Titan-sized satellite pp. 943-946

Robin M. Canup

Pleats in crystals on curved surfaces pp. 947-951

William T. M. Irvine, Vincenzo Vitelli and Paul M. Chaikin

Tidal dissipation and the strength of the Earth’s internal magnetic field pp. 952-954

Bruce A. Buffett

Greenhouse gas mitigation can reduce sea-ice loss and increase polar bear persistence pp. 955-958

Steven C. Amstrup, Eric T. DeWeaver, David C. Douglas, Bruce G. Marcot, George M. Durner, Cecilia M. Bitz and David A. Bailey

Intercalation of a new tier of transcription regulation into an ancient circuit pp. 959-963

Lauren N. Booth, Brian B. Tuch and Alexander D. Johnson

Noise correlations improve response fidelity and stimulus encoding pp. 964-967

Jon Cafaro and Fred Rieke

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation pp. 968-972

Cory M. Johannessen, Jesse S. Boehm, So Young Kim, Sapana R. Thomas, Leslie Wardwell, Laura A. Johnson, Caroline M. Emery, Nicolas Stransky, Alexandria P. Cogdill, Jordi Barretina, Giordano Caponigro, Haley Hieronymus, Ryan R. Murray, Kourosh Salehi-Ashtiani, David E. Hill, Marc Vidal, Jean J. Zhao, Xiaoping Yang, Ozan Alkan, Sungjoon Kim, Jennifer L. Harris, Christopher J. Wilson, Vic E. Myer, Peter M. Finan, David E. Root, Thomas M. Roberts, Todd Golub, Keith T. Flaherty, Reinhard Dummer, Barbara L. Weber, William R. Sellers, Robert Schlegel, Jennifer A. Wargo, William C. Hahn and Levi A. Garraway

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation pp. 973-977

Ramin Nazarian, Hubing Shi, Qi Wang, Xiangju Kong, Richard C. Koya, Hane Lee, Zugen Chen, Mi-Kyung Lee, Narsis Attar, Hooman Sazegar, Thinle Chodon, Stanley F. Nelson, Grant McArthur, Jeffrey A. Sosman, Antoni Ribas and Roger S. Lo

Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein pp. 978-982

Shunsuke Tagami, Shun-ichi Sekine, Thirumananseri Kumarevel, Nobumasa Hino, Yuko Murayama, Syunsuke Kamegamori, Masaki Yamamoto, Kensaku Sakamoto and Shigeyuki Yokoyama

Single-molecule imaging reveals mechanisms of protein disruption by a DNA translocase pp. 983-987

Ilya J. Finkelstein, Mari-Liis Visnapuu and Eric C. Greene

The mechanism of sodium and substrate release from the binding pocket of vSGLT pp. 988-991

Akira Watanabe, Seungho Choe, Vincent Chaptal, John M. Rosenberg, Ernest M. Wright, Michael Grabe and Jeff Abramson

Collaboration: Social networking seeks critical mass pp. 993-994

Virginia Gewin

Turning point: Francesca Malfatti pp. 994-994

Virginia Gewin

Silence pp. 996-996

John Frizell

2010, volume 468, articles 7325

Global systematics of arc volcano position pp. E6-E7

Philip C. England and Richard F. Katz

Grove et al. reply pp. E7-E8

T. L. Grove, C. B. Till, E. Lev, N. Chatterjee and E. Médard

Women scientists must speak out pp. 733-733

Jennifer Rohn

Islands champion tuna ban pp. 739-740

Christopher Pala

Microbe gets toxic response pp. 741-741

Alla Katsnelson

Basel Declaration defends animal research pp. 742-742

Alison Abbott

Trial draws fire pp. 743-743

Declan Butler

River chief resigns pp. 744-744

Stephen Pincock

Self-plagiarism case prompts calls for agencies to tighten rules pp. 745-745

Eugenie Samuel Reich

Stem-cell progress pp. 746-746

Ewen Callaway

Condensed matter: The supersolid's nemesis pp. 748-750

Eugenie Samuel Reich

Food: A taste of things to come? pp. 752-753

Nicola Jones

Lessons from Bayh–Dole pp. 755-756

Bhaven N. Sampat

More for the research dollar pp. 757-758

Jeffrey L. Furman, Fiona Murray and Scott Stern

Biography: The ABC of computing pp. 760-761

John Gilbey

Sculpture: Engineering art pp. 762-763

Neil Dodgson

Bibliometrics: Measure for measure pp. 763-763

Ton van Raan

Conservation: A magical process pp. 764-764

Philip Stott

Ease public concern over oil pipeline pp. 765-765

John B. Gates

Sustainable cities: seeing past the trees pp. 765-765

Rob MacKenzie, Tom Pugh and Chris Rogers

Time to underpin Wikipedia wisdom pp. 765-765

Alex Bateman and Darren W. Logan

Guest authors: for contributors only pp. 765-765

Mark J. van Raaij

Guest authors: no place in any journal pp. 765-765

Richard M. Glass

Michael Tinkham (1928–2010) pp. 766-766

Malcolm Beasley

Genomic hourglass pp. 768-769

Benjamin Prud'homme and Nicolas Gompel

Hot entanglement pp. 769-770

Vlatko Vedral

Tumour stem cells switch sides pp. 770-771

Victoria L. Bautch

Hydrogen was not ionized abruptly pp. 772-773

Jonathan Pritchard and Abraham Loeb

One protein, many functions pp. 773-775

Félix A. Rey

Pluto is again a harbinger pp. 775-776

S. Alan Stern

Greenland's glacial basics pp. 776-777

Martin P. Lüthi

Cap binding and immune evasion revealed by Lassa nucleoprotein structure pp. 779-783

Xiaoxuan Qi, Shuiyun Lan, Wenjian Wang, Lisa McLay Schelde, Haohao Dong, Gregor D. Wallat, Hinh Ly, Yuying Liang and Changjiang Dong

Structure of a bacterial ribonuclease P holoenzyme in complex with tRNA pp. 784-789

Nicholas J. Reiter, Amy Osterman, Alfredo Torres-Larios, Kerren K. Swinger, Tao Pan and Alfonso Mondragón

Quantitative reactivity profiling predicts functional cysteines in proteomes pp. 790-795

Eranthie Weerapana, Chu Wang, Gabriel M. Simon, Florian Richter, Sagar Khare, Myles B. D. Dillon, Daniel A. Bachovchin, Kerri Mowen, David Baker and Benjamin F. Cravatt

A lower limit of Δz > 0.06 for the duration of the reionization epoch pp. 796-798

Judd D. Bowman and Alan E. E. Rogers

Snapshots of cooperative atomic motions in the optical suppression of charge density waves pp. 799-802

Maximilian Eichberger, Hanjo Schäfer, Marina Krumova, Markus Beyer, Jure Demsar, Helmuth Berger, Gustavo Moriena, Germán Sciaini and R. J. Dwayne Miller

Ice-sheet acceleration driven by melt supply variability pp. 803-806

Christian Schoof

Outer-core compositional stratification from observed core wave speed profiles pp. 807-810

George Helffrich and Satoshi Kaneshima

Gene expression divergence recapitulates the developmental hourglass model pp. 811-814

Alex T. Kalinka, Karolina M. Varga, Dave T. Gerrard, Stephan Preibisch, David L. Corcoran, Julia Jarrells, Uwe Ohler, Casey M. Bergman and Pavel Tomancak

A phylogenetically based transcriptome age index mirrors ontogenetic divergence patterns pp. 815-818

Tomislav Domazet-Lošo and Diethard Tautz

Interdependence of behavioural variability and response to small stimuli in bacteria pp. 819-823

Heungwon Park, William Pontius, Calin C. Guet, John F. Marko, Thierry Emonet and Philippe Cluzel

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells pp. 824-828

Lucia Ricci-Vitiani, Roberto Pallini, Mauro Biffoni, Matilde Todaro, Gloria Invernici, Tonia Cenci, Giulio Maira, Eugenio Agostino Parati, Giorgio Stassi, Luigi Maria Larocca and Ruggero De Maria

Glioblastoma stem-like cells give rise to tumour endothelium pp. 829-833

Rong Wang, Kalyani Chadalavada, Jennifer Wilshire, Urszula Kowalik, Koos E. Hovinga, Adam Geber, Boris Fligelman, Margaret Leversha, Cameron Brennan and Viviane Tabar

Calcium-dependent phospholipid scrambling by TMEM16F pp. 834-838

Jun Suzuki, Masato Umeda, Peter J. Sims and Shigekazu Nagata

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2 pp. 839-843

Myunggon Ko, Yun Huang, Anna M. Jankowska, Utz Pape, Mamta Tahiliani, Hozefa S. Bandukwala, Jungeun An, Edward D. Lamperti, Kian Peng Koh, Rebecca Ganetzky, X. Shirley Liu, L. Aravind, Suneet Agarwal, Jaroslaw P. Maciejewski and Anjana Rao

Design, function and structure of a monomeric ClC transporter pp. 844-847

Janice L. Robertson, Ludmila Kolmakova-Partensky and Christopher Miller

Interactome under construction pp. 851-852

Laura Bonetta

Public health: Food-safety sentinels pp. 857-858

Laura Cassiday

Turning point: Charalampos Kalodimos pp. 859-859

Virginia Gewin

The cleverest man in the world pp. 862-862

Tony Ballantyne

2010, volume 468, articles 7324

A sustainable planet needs scientists to think ahead pp. 601-601

Sybil Seitzinger

Iranian nuclear scientists attacked pp. 607-607

Declan Butler

Complex synthesis yields breast-cancer therapy pp. 608-609

Heidi Ledford

Physics centre plans rapid growth pp. 609-609

Ivan Semeniuk

Partners wanted to run research lab in space pp. 610-611

Adam Mann

India blocks nuclear meeting pp. 613-613

Geoff Brumfiel

Chemists help archaeologists to probe biblical history pp. 614-615

Haim Watzman

Stem cells: The impatient advocate pp. 620-623

Elie Dolgin

Energy: Supergrid pp. 624-625

Colin Macilwain

Follow the money pp. 627-628

Philip Shapira and Jue Wang

Biography: Envy and power pp. 629-630

Robert P. Crease

Neuroscience: Patterns from the brain pp. 630-631

Vincent A. Billock

History: How to behave beyond the grave pp. 632-633

Andrew Robinson

Technology: Libraries of the future pp. 633-633

Aleks Krotoski

Archiving lessons from radiobiology pp. 634-634

Paul N. Schofield, Soile Tapio and Bernd Grosche

The politics of climate (dis)belief pp. 634-634

Francis Nicholson

How to conserve the tropics as they warm pp. 634-634

Jedediah Brodie, Eric Post and William Laurance

Faraday on the fiscal benefits of science pp. 634-634

Michael Polymenis

A cloudy view of exoplanets pp. 636-637

Drake Deming

Chemotherapy counteracted pp. 637-638

Urban Emmenegger and Robert S. Kerbel

Sexy circuits pp. 639-640

Richard Benton

Weighing up protein folding pp. 640-641

Martin Gruebele

Nematode debt to bacteria pp. 641-642

Noah K. Whiteman and Andrew D. Gloss

How the cuprates hid their stripes pp. 643-644

Kathryn A. Moler

The blood balance pp. 644-645

Ellen M. Durand and Leonard I. Zon

An alphavirus puzzle solved pp. 645-646

Margaret Kielian

Impacts of biodiversity on the emergence and transmission of infectious diseases pp. 647-652

Felicia Keesing, Lisa K. Belden, Peter Daszak, Andrew Dobson, C. Drew Harvell, Robert D. Holt, Peter Hudson, Anna Jolles, Kate E. Jones, Charles E. Mitchell, Samuel S. Myers, Tiffany Bogich and Richard S. Ostfeld

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells pp. 653-658

Daisuke Nakada, Thomas L. Saunders and Sean J. Morrison

The Lkb1 metabolic sensor maintains haematopoietic stem cell survival pp. 659-663

Sushma Gurumurthy, Stephanie Z. Xie, Brinda Alagesan, Judith Kim, Rushdia Z. Yusuf, Borja Saez, Alexandros Tzatsos, Fatih Ozsolak, Patrice Milos, Francesco Ferrari, Peter J. Park, Orian S. Shirihai, David T. Scadden and Nabeel Bardeesy

U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation pp. 664-668

Daisuke Kaida, Michael G. Berg, Ihab Younis, Mumtaz Kasim, Larry N. Singh, Lili Wan and Gideon Dreyfuss

A ground-based transmission spectrum of the super-Earth exoplanet GJ 1214b pp. 669-672

Jacob L. Bean, Eliza Miller-Ricci Kempton and Derek Homeier

Trapped antihydrogen pp. 673-676

G. B. Andresen, M. D. Ashkezari, M. Baquero-Ruiz, W. Bertsche, P. D. Bowe, E. Butler, C. L. Cesar, S. Chapman, M. Charlton, A. Deller, S. Eriksson, J. Fajans, T. Friesen, M. C. Fujiwara, D. R. Gill, A. Gutierrez, J. S. Hangst, W. N. Hardy, M. E. Hayden, A. J. Humphries, R. Hydomako, M. J. Jenkins, S. Jonsell, L. V. Jørgensen, L. Kurchaninov, N. Madsen, S. Menary, P. Nolan, K. Olchanski, A. Olin, A. Povilus, P. Pusa, F. Robicheaux, E. Sarid, S. Seif el Nasr, D. M. Silveira, C. So, J. W. Storey, R. I. Thompson, D. P. van der Werf, J. S. Wurtele and Y. Yamazaki

Fluctuating stripes at the onset of the pseudogap in the high-Tc superconductor Bi2Sr2CaCu2O8+x pp. 677-680

Colin V. Parker, Pegor Aynajian, Eduardo H. da Silva Neto, Aakash Pushp, Shimpei Ono, Jinsheng Wen, Zhijun Xu, Genda Gu and Ali Yazdani

The redox state of arc mantle using Zn/Fe systematics pp. 681-685

Cin-Ty A. Lee, Peter Luffi, Véronique Le Roux, Rajdeep Dasgupta, Francis Albaréde and William P. Leeman

A dimorphic pheromone circuit in Drosophila from sensory input to descending output pp. 686-690

Vanessa Ruta, Sandeep Robert Datta, Maria Luisa Vasconcelos, Jessica Freeland, Loren L. Looger and Richard Axel

Acid sensing by the Drosophila olfactory system pp. 691-695

Minrong Ai, Soohong Min, Yael Grosjean, Charlotte Leblanc, Rati Bell, Richard Benton and Greg S. B. Suh

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1 pp. 696-700

Jaime N. Guzman, Javier Sanchez-Padilla, David Wokosin, Jyothisri Kondapalli, Ema Ilijic, Paul T. Schumacker and D. James Surmeier

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells pp. 701-704

Boyi Gan, Jian Hu, Shan Jiang, Yingchun Liu, Ergün Sahin, Li Zhuang, Eliot Fletcher-Sananikone, Simona Colla, Y. Alan Wang, Lynda Chin and Ronald A. DePinho

Structural changes of envelope proteins during alphavirus fusion pp. 705-708

Long Li, Joyce Jose, Ye Xiang, Richard J. Kuhn and Michael G. Rossmann

Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography pp. 709-712

James E. Voss, Marie-Christine Vaney, Stéphane Duquerroy, Clemens Vonrhein, Christine Girard-Blanc, Elodie Crublet, Andrew Thompson, Gérard Bricogne and Félix A. Rey

Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites pp. 713-716

Andreas H. Ratje, Justus Loerke, Aleksandra Mikolajka, Matthias Brünner, Peter W. Hildebrand, Agata L. Starosta, Alexandra Dönhöfer, Sean R. Connell, Paola Fucini, Thorsten Mielke, Paul C. Whitford, José N. Onuchic, Yanan Yu, Karissa Y. Sanbonmatsu, Roland K. Hartmann, Pawel A. Penczek, Daniel N. Wilson and Christian M. T. Spahn

Structure and mechanism of the S component of a bacterial ECF transporter pp. 717-720

Peng Zhang, Jiawei Wang and Yigong Shi

Publishing: A helping hand pp. 721-723

Karen Kaplan

The age of momentum pp. 726-726

T. F. Davenport

2010, volume 468, articles 7323

Bold claims for optogenetics pp. E3-E4

Nikos K. Logothetis

Lee et al. reply pp. E4-E5

Jin Hyung Lee, Remy Durand, Viviana Gradinaru, Feng Zhang, Inbal Goshen, Dae-Shik Kim, Lief E. Fenno, Charu Ramakrishnan and Karl Deisseroth

Copenhagen shows we need caution in Cancún pp. 477-477

Yvo de Boer

Cholera tightens grip on Haiti pp. 483-484

Declan Butler

Korean deaths spark inquiry pp. 485-485

David Cyranoski

Nobel document triggers debate pp. 486-486

Eugenie Samuel Reich

Drug giants turn their backs on RNA interference pp. 487-487

Heidi Ledford

Climate talks focus on lesser goals pp. 488-489

Jeff Tollefson

The roots of resistance pp. 490-490

Heidi Ledford

Microbiology: The new germ theory pp. 492-495

Lizzie Buchen

Ancient astronomy: Mechanical inspiration pp. 496-498

Jo Marchant

Tar sands need solid science pp. 499-501

David Schindler

Call in the women pp. 502-502

Susan Buckingham

Conservation: China's national treasure pp. 503-504

Jane Qiu

History: Catching up with the Sun pp. 504-505

Douglas Gough

Sculpture: Terrible wonder pp. 506-507

Martin Kemp

Innovation: The ideas lab pp. 507-507

Jascha Hoffman

IPCC yet to assess geoengineering pp. 508-508

Ottmar Edenhofer

An intellectual black hole pp. 508-508

Larry Gilman

Space telescope is worth the effort pp. 508-508

Matt Mountain, John Grunsfeld and Heidi Hammel

Raiding the sweet shop pp. 510-511

Nicholas J. Talbot

Geometry of the Universe pp. 511-512

Alan Heavens

Early Homo sapiens in China pp. 512-513

Robin Dennell

Import and nuclear size pp. 513-516

Orna Cohen-Fix

Peptides as biological semiconductors pp. 516-517

Charlotte A. E. Hauser and Shuguang Zhang

Particles of light pp. 517-518

James Anglin

Cellular seat belts pp. 518-519

Yuta Shimamoto and Tarun M. Kapoor

The blind spot of p53 pp. 519-520

Anton Berns

Direct conversion of human fibroblasts to multilineage blood progenitors pp. 521-526

Eva Szabo, Shravanti Rampalli, Ruth M. Risueño, Angelique Schnerch, Ryan Mitchell, Aline Fiebig-Comyn, Marilyne Levadoux-Martin and Mickie Bhatia

Sugar transporters for intercellular exchange and nutrition of pathogens pp. 527-532

Li-Qing Chen, Bi-Huei Hou, Sylvie Lalonde, Hitomi Takanaga, Mara L. Hartung, Xiao-Qing Qu, Woei-Jiun Guo, Jung-Gun Kim, William Underwood, Bhavna Chaudhuri, Diane Chermak, Ginny Antony, Frank F. White, Shauna C. Somerville, Mary Beth Mudgett and Wolf B. Frommer

Structure and control of the actin regulatory WAVE complex pp. 533-538

Zhucheng Chen, Dominika Borek, Shae B. Padrick, Timothy S. Gomez, Zoltan Metlagel, Ayman M. Ismail, Junko Umetani, Daniel D. Billadeau, Zbyszek Otwinowski and Michael K. Rosen

A geometric measure of dark energy with pairs of galaxies pp. 539-541

Christian Marinoni and Adeline Buzzi

The dynamical mass of a classical Cepheid variable star in an eclipsing binary system pp. 542-544

G. Pietrzyński, I. B. Thompson, W. Gieren, D. Graczyk, G. Bono, A. Udalski, I. Soszyński, D. Minniti and B. Pilecki

Bose–Einstein condensation of photons in an optical microcavity pp. 545-548

Jan Klaers, Julian Schmitt, Frank Vewinger and Martin Weitz

Growth of graphene from solid carbon sources pp. 549-552

Zhengzong Sun, Zheng Yan, Jun Yao, Elvira Beitler, Yu Zhu and James M. Tour

Bottom-up effects of plant diversity on multitrophic interactions in a biodiversity experiment pp. 553-556

Christoph Scherber, Nico Eisenhauer, Wolfgang W. Weisser, Bernhard Schmid, Winfried Voigt, Markus Fischer, Ernst-Detlef Schulze, Christiane Roscher, Alexandra Weigelt, Eric Allan, Holger Beßler, Michael Bonkowski, Nina Buchmann, François Buscot, Lars W. Clement, Anne Ebeling, Christof Engels, Stefan Halle, Ilona Kertscher, Alexandra-Maria Klein, Robert Koller, Stephan König, Esther Kowalski, Volker Kummer, Annely Kuu, Markus Lange, Dirk Lauterbach, Cornelius Middelhoff, Varvara D. Migunova, Alexandru Milcu, Ramona Müller, Stephan Partsch, Jana S. Petermann, Carsten Renker, Tanja Rottstock, Alexander Sabais, Stefan Scheu, Jens Schumacher, Vicky M. Temperton and Teja Tscharntke

Pericytes regulate the blood–brain barrier pp. 557-561

Annika Armulik, Guillem Genové, Maarja Mäe, Maya H. Nisancioglu, Elisabet Wallgard, Colin Niaudet, Liqun He, Jenny Norlin, Per Lindblom, Karin Strittmatter, Bengt R. Johansson and Christer Betsholtz

Pericytes are required for blood–brain barrier integrity during embryogenesis pp. 562-566

Richard Daneman, Lu Zhou, Amanuel A. Kebede and Ben A. Barres

Selective activation of p53-mediated tumour suppression in high-grade tumours pp. 567-571

Melissa R. Junttila, Anthony N. Karnezis, Daniel Garcia, Francesc Madriles, Roderik M. Kortlever, Fanya Rostker, Lamorna Brown Swigart, David M. Pham, Youngho Seo, Gerard I. Evan and Carla P. Martins

Stage-specific sensitivity to p53 restoration during lung cancer progression pp. 572-575

David M. Feldser, Kamena K. Kostova, Monte M. Winslow, Sarah E. Taylor, Chris Cashman, Charles A. Whittaker, Francisco J. Sanchez-Rivera, Rebecca Resnick, Roderick Bronson, Michael T. Hemann and Tyler Jacks

Tension directly stabilizes reconstituted kinetochore-microtubule attachments pp. 576-579

Bungo Akiyoshi, Krishna K. Sarangapani, Andrew F. Powers, Christian R. Nelson, Steve L. Reichow, Hugo Arellano-Santoyo, Tamir Gonen, Jeffrey A. Ranish, Charles L. Asbury and Sue Biggins

Nanoscale architecture of integrin-based cell adhesions pp. 580-584

Pakorn Kanchanawong, Gleb Shtengel, Ana M. Pasapera, Ericka B. Ramko, Michael W. Davidson, Harald F. Hess and Clare M. Waterman

The amino-terminal disease hotspot of ryanodine receptors forms a cytoplasmic vestibule pp. 585-588

Ching-Chieh Tung, Paolo A. Lobo, Lynn Kimlicka and Filip Van Petegem

Small science yields big growth pp. 589-590

Corinna Wu

Turning point: Mary Gehring pp. 591-591

Virginia Gewin

High on the hog pp. 594-594

Sean Davidson

2010, volume 468, articles 7322

Curiouser and curiouser: managing discovery making pp. 347-347

Ahmed Zewail

Scope sails into budget void pp. 353-354

Adam Mann

Good news for 'good' cholesterol pp. 354-354

Alla Katsnelson

Antimatter held for questioning pp. 355-355

Eugenie Samuel Reich

Study says middle sized labs do best pp. 356-357

Meredith Wadman

UK science will be judged on impact pp. 357-357

Natasha Gilbert

Germany plans for healthy future pp. 358-359

Alison Abbott

No rest for the bio-wikis pp. 359-360

Ewen Callaway

Climate: The hottest year pp. 362-364

David Adam

Science communication: Scientist as star pp. 365-366

Erik Vance

The end of cheap coal pp. 367-369

Richard Heinberg and David Fridley

Questioning economic growth pp. 370-371

Peter Victor

Society: The rise of the 'technium' pp. 372-373

Zaheer Baber

Agriculture: Greenhouses in the sky pp. 374-374

Emma Marris

History: Franklin, centre stage pp. 375-375

Josie Glausiusz

Painting: Inquisitive and exact pp. 376-376

Alison Abbott

European bounty for taxonomists pp. 377-377

Benoît Fontaine

Innovation in Europe — three questions pp. 377-377

Wouter Boon and Gaston Heimeriks

Misreporting: a glowing report pp. 377-377

Robert Matthews

Reef technology to rescue Venice pp. 377-377

Thomas J. Goreau

Benoît Mandelbrot (1924–2010) pp. 378-378

Ralph Gomory

Synthetic metabolism goes green pp. 380-381

Joseph P. Noel

Clear signals from surfaces pp. 381-382

Robert G. Griffin

Excessive mobility interrupted pp. 383-384

Lorenz Studer

Entangled quartet pp. 384-385

Vladan Vuletic

Measuring biodiversity in marine ecosystems pp. 385-386

Joseph E. Powers

Of worms and women pp. 386-387

Kevin Flurkey and David E. Harrison

Thin films with a hidden twist pp. 387-388

Andreas Stein

The moment of truth for WIMP dark matter pp. 389-393

Gianfranco Bertone

Support for a synaptic chain model of neuronal sequence generation pp. 394-399

Michael A. Long, Dezhe Z. Jin and Michale S. Fee

Jasmonate perception by inositol-phosphate-potentiated COI1–JAZ co-receptor pp. 400-405

Laura B. Sheard, Xu Tan, Haibin Mao, John Withers, Gili Ben-Nissan, Thomas R. Hinds, Yuichi Kobayashi, Fong-Fu Hsu, Michal Sharon, John Browse, Sheng Yang He, Josep Rizo, Gregg A. Howe and Ning Zheng

An unprecedented nucleic acid capture mechanism for excision of DNA damage pp. 406-411

Emily H. Rubinson, A. S. Prakasha Gowda, Thomas E. Spratt, Barry Gold and Brandt F. Eichman

Entanglement of spin waves among four quantum memories pp. 412-416

K. S. Choi, A. Goban, S. B. Papp, S. J. van Enk and H. J. Kimble

Quantum tunnelling of the magnetization in a monolayer of oriented single-molecule magnets pp. 417-421

M. Mannini, F. Pineider, C. Danieli, F. Totti, L. Sorace, Ph. Sainctavit, M.-A. Arrio, E. Otero, L. Joly, J. C. Cezar, A. Cornia and R. Sessoli

Free-standing mesoporous silica films with tunable chiral nematic structures pp. 422-425

Kevin E. Shopsowitz, Hao Qi, Wadood Y. Hamad and Mark J. MacLachlan

Intrusion triggering of the 2010 Eyjafjallajökull explosive eruption pp. 426-430

Freysteinn Sigmundsson, Sigrún Hreinsdóttir, Andrew Hooper, Thóra Árnadóttir, Rikke Pedersen, Matthew J. Roberts, Níels Óskarsson, Amandine Auriac, Judicael Decriem, Páll Einarsson, Halldór Geirsson, Martin Hensch, Benedikt G. Ófeigsson, Erik Sturkell, Hjörleifur Sveinbjörnsson and Kurt L. Feigl

The trophic fingerprint of marine fisheries pp. 431-435

Trevor A. Branch, Reg Watson, Elizabeth A. Fulton, Simon Jennings, Carey R. McGilliard, Grace T. Pablico, Daniel Ricard and Sean R. Tracey

Climate-driven population divergence in sex-determining systems pp. 436-438

Ido Pen, Tobias Uller, Barbara Feldmeyer, Anna Harts, Geoffrey M. While and Erik Wapstra

A widespread family of polymorphic contact-dependent toxin delivery systems in bacteria pp. 439-442

Stephanie K. Aoki, Elie J. Diner, Claire t’Kint de Roodenbeke, Brandt R. Burgess, Stephen J. Poole, Bruce A. Braaten, Allison M. Jones, Julia S. Webb, Christopher S. Hayes, Peggy A. Cotter and David A. Low

L1 retrotransposition in neurons is modulated by MeCP2 pp. 443-446

Alysson R. Muotri, Maria C. N. Marchetto, Nicole G. Coufal, Ruth Oefner, Gene Yeo, Kinichi Nakashima and Fred H. Gage

The structural basis for membrane binding and pore formation by lymphocyte perforin pp. 447-451

Ruby H. P. Law, Natalya Lukoyanova, Ilia Voskoboinik, Tom T. Caradoc-Davies, Katherine Baran, Michelle A. Dunstone, Michael E. D’Angelo, Elena V. Orlova, Fasséli Coulibaly, Sandra Verschoor, Kylie A. Browne, Annette Ciccone, Michael J. Kuiper, Phillip I. Bird, Joseph A. Trapani, Helen R. Saibil and James C. Whisstock

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members pp. 452-456

Stephane Daffis, Kristy J. Szretter, Jill Schriewer, Jianqing Li, Soonjeon Youn, John Errett, Tsai-Yu Lin, Stewart Schneller, Roland Zust, Hongping Dong, Volker Thiel, Ganes C. Sen, Volker Fensterl, William B. Klimstra, Theodore C. Pierson, R. Mark Buller, Michael Gale, Pei-Yong Shi and Michael S. Diamond

Molecular coupling of Tsix regulation and pluripotency pp. 457-460

Pablo Navarro, Andrew Oldfield, Julie Legoupi, Nicola Festuccia, Agnès Dubois, Mikael Attia, Jon Schoorlemmer, Claire Rougeulle, Ian Chambers and Philip Avner

Integrating carbon–halogen bond formation into medicinal plant metabolism pp. 461-464

Weerawat Runguphan, Xudong Qu and Sarah E. O’Connor

Outreach: Meet the press pp. 465-467

Gene Russo

A CV of failures pp. 467-467

Melanie Stefan

World wire web pp. 470-470

Gareth D. Jones

2010, volume 468, articles 7321

A way of life pp. 1-1

Katherine Sixt

Double trouble? To throw cash at science is a mistake pp. 135-135

Daniel Sarewitz

Measuring the meltdown pp. 141-142

Jane Qiu

Vaccine offers meningitis hope pp. 143-143

Declan Butler

China tackles surge in mental illness pp. 145-145

David Cyranoski

US science faces a squeeze pp. 146-147

Richard Monastersky, Jeff Tollefson, Meredith Wadman and Eugenie Samuel Reich

Funding crisis hits US ageing research pp. 148-148

Meredith Wadman

There will be blood pp. 149-149

Ewen Callaway

Schizophrenia: The making of a troubled mind pp. 154-156

David Dobbs

Schizophrenia: The drug deadlock pp. 158-159

Alison Abbott

Neuroscience: Settling the great glia debate pp. 160-162

Kerri Smith

Short-lived campaigns are not enough pp. 163-165

Norman Sartorius

Cognitive remediation therapy needs funding pp. 165-166

Til Wykes

In retrospect: The five lives of the psychiatry manual pp. 168-169

Roy Richard Grinker

Innovation: Lighting the creative spark pp. 170-171

Robert J. Sternberg

Q&A: On facts and fiction pp. 172-172

Jennifer Rohn

Cities need plants and animals too pp. 173-173

Patrick R. Huber and Steven E. Greco

Water: act now to restore river health pp. 173-173

Patrick Dugan and Edward H. Allison

Water: biofuels sap supplies pp. 173-173

Bobban Subhadra

Ireland should fund best research pp. 173-173

Gareth Dyke

Concrete helix recalls smallpox win pp. 173-173

Julio Licinio, Simon Easteal and Ma-Li Wong

John Huchra (1948–2010) pp. 174-174

Robert Kirshner

Recovery inhibitors under attack pp. 176-177

Kevin Staley

A diverse printed future pp. 177-178

John A. Rogers

The split view of motion pp. 178-179

Chi -Hon Lee

How to confuse thirsty bats pp. 181-181

Stefano Tonzani

Big G revisited pp. 181-182

Richard Davis

When abnormality is beneficial pp. 183-184

Judith Berman

Mind the pseudogap pp. 184-185

Chandra Varma

Rethinking schizophrenia pp. 187-193

Thomas R. Insel

From maps to mechanisms through neuroimaging of schizophrenia pp. 194-202

Andreas Meyer-Lindenberg

The environment and schizophrenia pp. 203-212

Jim van Os, Gunter Kenis and Bart P. F. Rutten

Glia pp. 213-213

Tanguy Chouard and Noah Gray

Developmental genetics of vertebrate glial–cell specification pp. 214-222

David H. Rowitch and Arnold R. Kriegstein

Regulation of synaptic connectivity by glia pp. 223-231

Cagla Eroglu and Ben A. Barres

Glial and neuronal control of brain blood flow pp. 232-243

David Attwell, Alastair M. Buchan, Serge Charpak, Martin Lauritzen, Brian A. MacVicar and Eric A. Newman

Myelination and support of axonal integrity by glia pp. 244-252

Klaus-Armin Nave

The myeloid cells of the central nervous system parenchyma pp. 253-262

Richard M. Ransohoff and Astrid E. Cardona

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes pp. 263-269

Hsiao-Tuan Chao, Hongmei Chen, Rodney C. Samaco, Mingshan Xue, Maria Chahrour, Jong Yoo, Jeffrey L. Neul, Shiaoching Gong, Hui-Chen Lu, Nathaniel Heintz, Marc Ekker, John L. R. Rubenstein, Jeffrey L. Noebels, Christian Rosenmund and Huda Y. Zoghbi

Genetic dissection of an amygdala microcircuit that gates conditioned fear pp. 270-276

Wulf Haubensak, Prabhat S. Kunwar, Haijiang Cai, Stephane Ciocchi, Nicholas R. Wall, Ravikumar Ponnusamy, Jonathan Biag, Hong-Wei Dong, Karl Deisseroth, Edward M. Callaway, Michael S. Fanselow, Andreas Lüthi and David J. Anderson

Encoding of conditioned fear in central amygdala inhibitory circuits pp. 277-282

Stephane Ciocchi, Cyril Herry, François Grenier, Steffen B. E. Wolff, Johannes J. Letzkus, Ioannis Vlachos, Ingrid Ehrlich, Rolf Sprengel, Karl Deisseroth, Michael B. Stadler, Christian Müller and Andreas Lüthi

Hidden magnetic excitation in the pseudogap phase of a high-Tc superconductor pp. 283-285

Yuan Li, V. Balédent, G. Yu, N. Barišić, K. Hradil, R. A. Mole, Y. Sidis, P. Steffens, X. Zhao, P. Bourges and M. Greven

Ultrathin compound semiconductor on insulator layers for high-performance nanoscale transistors pp. 286-289

Hyunhyub Ko, Kuniharu Takei, Rehan Kapadia, Steven Chuang, Hui Fang, Paul W. Leu, Kartik Ganapathi, Elena Plis, Ha Sul Kim, Szu-Ying Chen, Morten Madsen, Alexandra C. Ford, Yu-Lun Chueh, Sanjay Krishna, Sayeef Salahuddin and Ali Javey

Early oxygenation of the terrestrial environment during the Mesoproterozoic pp. 290-293

John Parnell, Adrian J. Boyce, Darren Mark, Stephen Bowden and Sam Spinks

Sequential faulting explains the asymmetry and extension discrepancy of conjugate margins pp. 294-299

César R. Ranero and Marta Pérez-Gussinyé

ON and OFF pathways in Drosophila motion vision pp. 300-304

Maximilian Joesch, Bettina Schnell, Shamprasad Varija Raghu, Dierk F. Reiff and Alexander Borst

Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke pp. 305-309

Andrew N. Clarkson, Ben S. Huang, Sarah E. MacIsaac, Istvan Mody and S. Thomas Carmichael

Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration pp. 310-315

Bi-Sen Ding, Daniel J. Nolan, Jason M. Butler, Daylon James, Alexander O. Babazadeh, Zev Rosenwaks, Vivek Mittal, Hideki Kobayashi, Koji Shido, David Lyden, Thomas N. Sato, Sina Y. Rabbany and Shahin Rafii

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity pp. 316-320

Na-Yu Chia, Yun-Shen Chan, Bo Feng, Xinyi Lu, Yuriy L. Orlov, Dimitri Moreau, Pankaj Kumar, Lin Yang, Jianming Jiang, Mei-Sheng Lau, Mikael Huss, Boon-Seng Soh, Petra Kraus, Pin Li, Thomas Lufkin, Bing Lim, Neil D. Clarke, Frederic Bard and Huck-Hui Ng

Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast pp. 321-325

Norman Pavelka, Giulia Rancati, Jin Zhu, William D. Bradford, Anita Saraf, Laurence Florens, Brian W. Sanderson, Gaye L. Hattem and Rong Li

The mechanism of retroviral integration from X-ray structures of its key intermediates pp. 326-329

Goedele N. Maertens, Stephen Hare and Peter Cherepanov

Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase pp. 330-333

Chengqi Yi, Guifang Jia, Guanhua Hou, Qing Dai, Wen Zhang, Guanqun Zheng, Xing Jian, Cai-Guang Yang, Qiang Cui and Chuan He

Erratum: Global threats to human water security and river biodiversity pp. 334-334

C. J. Vörösmarty, P. B. McIntyre, M. O. Gessner, D. Dudgeon, A. Prusevich, P. Green, S. Glidden, S. E. Bunn, C. A. Sullivan, C. Reidy Liermann and P. M. Davies

Awards: Thumbs up for Canadian mentors pp. 335-336

Nicola Jones

Turning point: Jacob Hanna pp. 337-337

Virginia Gewin

George and Priti pp. 340-340

Anand Odhav Naranbhai

2010, volume 468, articles 7320

Moulting tail feathers in a juvenile oviraptorisaur pp. E1-E1

Richard O. Prum

Xu et al. reply pp. E2-E2

Xing Xu, Xiaoting Zheng and Hailu You

How to beat the media in the climate street fight pp. 7-7

Simon L. Lewis

Geoengineering faces ban pp. 13-14

Jeff Tollefson

World gets 2020 vision for conservation pp. 14-14

Anjali Nayar

Cosmic blasts hint at inner magnetars pp. 15-15

Eugenie Samuel Reich

Curtain falls on collaborative work pp. 16-16

Geoff Brumfiel

Researchers launch hunt for endangered data pp. 17-17

Linda Nordling

'Biosimilar' drugs poised to penetrate market pp. 18-19

Heidi Ledford

Brazil's climate modellers are set to go global pp. 20-20

Jeff Tollefson

Genomics: DNA's master craftsmen pp. 22-25

Roberta Kwok

Marine science: The tiniest catch pp. 26-27

Wendee Holtcamp

Transparency showcases strength of peer review pp. 29-31

Bernd Pulverer

Psychology: A social animal revealed pp. 32-33

W. F. Bynum

Books in brief pp. 33-33

Joanne Baker

Developmental biology: The whole nine months pp. 34-34

Michael Sargent

Communication: Learning to love science films pp. 35-36

Carl Zimmer

Computer code: more credit needed pp. 37-37

Herman Tse

Computer code: incentives needed pp. 37-37

Konrad Hinsen

Computer code: a model journal pp. 37-37

Dan Lunt

Reviewer disclaims competing interest pp. 37-37

Daniel S. Greenberg

More insights from Crick's lost letters pp. 37-37

Robert Olby

Gravity's weight on unification pp. 40-41

Giovanni Amelino-Camelia

Conditional stability of T cells pp. 41-42

Shimon Sakaguchi

Podocytes lose their footing pp. 42-44

Christian Rask-Madsen and George L. King

Myosin in motion pp. 43-43

Deepa Nath

Quantum RAM pp. 44-45

Miles Blencowe

Slicer for DNA pp. 45-46

Erik J. Sontheimer and Luciano A. Marraffini

On stress and pressure pp. 46-47

Curt D. Sigmund

Early star-forming galaxies and the reionization of the Universe pp. 49-55

Brant E. Robertson, Richard S. Ellis, James S. Dunlop, Ross J. McLure and Daniel P. Stark

Quantum gravitational contributions to quantum electrodynamics pp. 56-59

David J. Toms

Genomic and functional adaptation in surface ocean planktonic prokaryotes pp. 60-66

Shibu Yooseph, Kenneth H. Nealson, Douglas B. Rusch, John P. McCrow, Christopher L. Dupont, Maria Kim, Justin Johnson, Robert Montgomery, Steve Ferriera, Karen Beeson, Shannon J. Williamson, Andrey Tovchigrechko, Andrew E. Allen, Lisa A. Zeigler, Granger Sutton, Eric Eisenstadt, Yu-Hui Rogers, Robert Friedman, Marvin Frazier and J. Craig Venter

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA pp. 67-71

Josiane E. Garneau, Marie-Ève Dupuis, Manuela Villion, Dennis A. Romero, Rodolphe Barrangou, Patrick Boyaval, Christophe Fremaux, Philippe Horvath, Alfonso H. Magadán and Sylvain Moineau

Video imaging of walking myosin V by high-speed atomic force microscopy pp. 72-76

Noriyuki Kodera, Daisuke Yamamoto, Ryoki Ishikawa and Toshio Ando

Formation of the black-hole binary M33 X-7 through mass exchange in a tight massive system pp. 77-79

Francesca Valsecchi, Evert Glebbeek, Will M. Farr, Tassos Fragos, Bart Willems, Jerome A. Orosz, Jifeng Liu and Vassiliki Kalogera

Holographic three-dimensional telepresence using large-area photorefractive polymer pp. 80-83

P.-A. Blanche, A. Bablumian, R. Voorakaranam, C. Christenson, W. Lin, T. Gu, D. Flores, P. Wang, W.-Y. Hsieh, M. Kathaperumal, B. Rachwal, O. Siddiqui, J. Thomas, R. A. Norwood, M. Yamamoto and N. Peyghambarian

Reversed flow of Atlantic deep water during the Last Glacial Maximum pp. 84-88

César Negre, Rainer Zahn, Alexander L. Thomas, Pere Masqué, Gideon M. Henderson, Gema Martínez-Méndez, Ian R. Hall and José L. Mas

Higher rates of sex evolve in spatially heterogeneous environments pp. 89-92

Lutz Becks and Aneil F. Agrawal

Antibodies to human serum amyloid P component eliminate visceral amyloid deposits pp. 93-97

Karl Bodin, Stephan Ellmerich, Melvyn C. Kahan, Glenys A. Tennent, Andrzej Loesch, Janet A. Gilbertson, Winston L. Hutchinson, Palma P. Mangione, J. Ruth Gallimore, David J. Millar, Shane Minogue, Amar P. Dhillon, Graham W. Taylor, Arthur R. Bradwell, Aviva Petrie, Julian D. Gillmore, Vittorio Bellotti, Marina Botto, Philip N. Hawkins and Mark B. Pepys

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer pp. 98-102

Daniel Schramek, Andreas Leibbrandt, Verena Sigl, Lukas Kenner, John A. Pospisilik, Heather J. Lee, Reiko Hanada, Purna A. Joshi, Antonios Aliprantis, Laurie Glimcher, Manolis Pasparakis, Rama Khokha, Christopher J. Ormandy, Martin Widschwendter, Georg Schett and Josef M. Penninger

RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis pp. 103-107

Eva Gonzalez-Suarez, Allison P. Jacob, Jon Jones, Robert Miller, Martine P. Roudier-Meyer, Ryan Erwert, Jan Pinkas, Dan Branstetter and William C. Dougall

A redox switch in angiotensinogen modulates angiotensin release pp. 108-111

Aiwu Zhou, Robin W. Carrell, Michael P. Murphy, Zhenquan Wei, Yahui Yan, Peter L. D. Stanley, Penelope E. Stein, Fiona Broughton Pipkin and Randy J. Read

A methyl transferase links the circadian clock to the regulation of alternative splicing pp. 112-116

Sabrina E. Sanchez, Ezequiel Petrillo, Esteban J. Beckwith, Xu Zhang, Matias L. Rugnone, C. Esteban Hernando, Juan C. Cuevas, Micaela A. Godoy Herz, Ana Depetris-Chauvin, Craig G. Simpson, John W. S. Brown, Pablo D. Cerdán, Justin O. Borevitz, Paloma Mas, M. Fernanda Ceriani, Alberto R. Kornblihtt and Marcelo J. Yanovsky

Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme pp. 117-121

Kimie Nakagawa, Yoshihisa Hirota, Natsumi Sawada, Naohito Yuge, Masato Watanabe, Yuri Uchino, Naoko Okuda, Yuka Shimomura, Yoshitomo Suhara and Toshio Okano

Erratum: Ecoenzymatic stoichiometry of microbial organic nutrient acquisition in soil and sediment pp. 122-122

Robert L. Sinsabaugh, Brian H. Hill and Jennifer J. Follstad Shah

Erratum: eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation pp. 122-122

Martin D. Jennings and Graham D. Pavitt

Retraction Note: The large-conductance Ca2+-activated K+ channel is essential for innate immunity pp. 122-122

Jatinder Ahluwalia, Andrew Tinker, Lucie H. Clapp, Michael R. Duchen, Andrey Y. Abramov, Simon Pope, Muriel Nobles and Anthony W. Segal

Academia: The changing face of tenure pp. 123-125

Karen Kaplan

Switzerland pp. 126-126

Katharine Sanderson

Ralph Eichler pp. 126-126

Katharine Sanderson

Bush meat pp. 128-128

Paul Renault