Alternating-access mechanism in conformationally asymmetric trimers of the betaine transporter BetP

Camilo Perez, Caroline Koshy, Özkan Yildiz and Christine Ziegler ()
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Camilo Perez: Max-Planck Institute of Biophysics
Caroline Koshy: Max-Planck Institute of Biophysics
Özkan Yildiz: Max-Planck Institute of Biophysics
Christine Ziegler: Max-Planck Institute of Biophysics

Nature, 2012, vol. 490, issue 7418, 126-130

Abstract: The crystal structure of the osmotically regulated symporter BetP is reported in four new conformations, providing information about the key conformational changes that take place during the transport cycle.

Date: 2012
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DOI: 10.1038/nature11403

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