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2012, volume 483, articles 7391

Scientists must be taught to manage pp. 511-511

Jessica C. Seeliger

Farm focus for saving trees pp. 517-518

Jeff Tollefson

Drug candidates derailed in case of mistaken identity pp. 519-519

Heidi Ledford

Flu surveillance lacking pp. 520-522

Declan Butler

North set for mass analysis of planets pp. 522-523

Eric Hand

Chemistry’s web of data expands pp. 524-524

Richard Van Noorden

African agriculture: Dirt poor pp. 525-527

Natasha Gilbert

Life-changing experiments: The biological Higgs pp. 528-530

Heidi Ledford

Raise standards for preclinical cancer research pp. 531-533

C. Glenn Begley and Lee M. Ellis

Shift expertise to where it matters pp. 534-535

Jeremy Farrar

Climate science: A delicate balance pp. 537-538

James F. Kasting

Linguistics: Sound sculptor pp. 538-539

John A. Goldsmith

Q&A: Descartes' decipherer pp. 540-540

Stephen Ornes

Peak oil is affecting the economy already pp. 541-541

David J. Murphy

Turing: Keep his work in perspective pp. 541-541

Jürgen Schmidhuber

Turing: A formal clash of codes pp. 541-541

Guenther Witzany and František Baluška

The case for brain imaging technology pp. 541-541

Bernd Weber

True value of climate fund's contribution pp. 541-541

Marcia Levaggi

Wylie Walker Vale Jr (1941–2012) pp. 542-542

Ronald Evans

Cell lines battle cancer pp. 544-545

John N. Weinstein

Terahertz collisions pp. 545-546

Rupert Huber

Clinical trials unite mice and humans pp. 547-548

Leisa Johnson

Tahitian record suggests Antarctic collapse pp. 549-550

Robert Kopp

Those feet in ancient times pp. 550-551

Daniel E. Lieberman

Evidence against a chondritic Earth pp. 553-558

Ian H. Campbell and Hugh St C. O’Neill

Ice-sheet collapse and sea-level rise at the Bølling warming 14,600 years ago pp. 559-564

Pierre Deschamps, Nicolas Durand, Edouard Bard, Bruno Hamelin, Gilbert Camoin, Alexander L. Thomas, Gideon M. Henderson, Jun'ichi Okuno and Yusuke Yokoyama

A new hominin foot from Ethiopia shows multiple Pliocene bipedal adaptations pp. 565-569

Yohannes Haile-Selassie, Beverly Z. Saylor, Alan Deino, Naomi E. Levin, Mulugeta Alene and Bruce M. Latimer

Systematic identification of genomic markers of drug sensitivity in cancer cells pp. 570-575

Mathew J. Garnett, Elena J. Edelman, Sonja J. Heidorn, Chris D. Greenman, Anahita Dastur, King Wai Lau, Patricia Greninger, I. Richard Thompson, Xi Luo, Jorge Soares, Qingsong Liu, Francesco Iorio, Didier Surdez, Li Chen, Randy J. Milano, Graham R. Bignell, Ah T. Tam, Helen Davies, Jesse A. Stevenson, Syd Barthorpe, Stephen R. Lutz, Fiona Kogera, Karl Lawrence, Anne McLaren-Douglas, Xeni Mitropoulos, Tatiana Mironenko, Helen Thi, Laura Richardson, Wenjun Zhou, Frances Jewitt, Tinghu Zhang, Patrick O’Brien, Jessica L. Boisvert, Stacey Price, Wooyoung Hur, Wanjuan Yang, Xianming Deng, Adam Butler, Hwan Geun Choi, Jae Won Chang, Jose Baselga, Ivan Stamenkovic, Jeffrey A. Engelman, Sreenath V. Sharma, Olivier Delattre, Julio Saez-Rodriguez, Nathanael S. Gray, Jeffrey Settleman, P. Andrew Futreal, Daniel A. Haber, Michael R. Stratton, Sridhar Ramaswamy, Ultan McDermott and Cyril H. Benes

Observation of a roton collective mode in a two-dimensional Fermi liquid pp. 576-579

Henri Godfrin, Matthias Meschke, Hans-Jochen Lauter, Ahmad Sultan, Helga M. Böhm, Eckhard Krotscheck and Martin Panholzer

Experimental observation of electron–hole recollisions pp. 580-583

B. Zaks, R. B. Liu and M. S. Sherwin

Spontaneous coherence in a cold exciton gas pp. 584-588

A. A. High, J. R. Leonard, A. T. Hammack, M. M. Fogler, L. V. Butov, A. V. Kavokin, K. L. Campman and A. C. Gossard

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes pp. 589-593

Jan J. Molenaar, Jan Koster, Danny A. Zwijnenburg, Peter van Sluis, Linda J. Valentijn, Ida van der Ploeg, Mohamed Hamdi, Johan van Nes, Bart A. Westerman, Jennemiek van Arkel, Marli E. Ebus, Franciska Haneveld, Arjan Lakeman, Linda Schild, Piet Molenaar, Peter Stroeken, Max M. van Noesel, Ingrid Øra, Evan E. Santo, Huib N. Caron, Ellen M. Westerhout and Rogier Versteeg

Deciphering a neuronal circuit that mediates appetite pp. 594-597

Qi Wu, Michael S. Clark and Richard D. Palmiter

Chromatin-modifying enzymes as modulators of reprogramming pp. 598-602

Tamer T. Onder, Nergis Kara, Anne Cherry, Amit U. Sinha, Nan Zhu, Kathrin M. Bernt, Patrick Cahan, B. Ogan Mancarci, Juli Unternaehrer, Piyush B. Gupta, Eric S. Lander, Scott A. Armstrong and George Q. Daley

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity pp. 603-607

Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehár, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy, Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jané-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guoying K. Yu, Jianjun Yu, Peter Aspesi, Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura MacConaill, Wendy Winckler, Michael Reich, Nanxin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Meyerson, Todd R. Golub, Michael P. Morrissey, William R. Sellers, Robert Schlegel and Levi A. Garraway

Deregulated MYC expression induces dependence upon AMPK-related kinase 5 pp. 608-612

Lidan Liu, Jannes Ulbrich, Judith Müller, Torsten Wüstefeld, Lukas Aeberhard, Theresia R. Kress, Nathiya Muthalagu, Lukas Rycak, Ramona Rudalska, Roland Moll, Stefan Kempa, Lars Zender, Martin Eilers and Daniel J. Murphy

A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response pp. 613-617

Zhao Chen, Katherine Cheng, Zandra Walton, Yuchuan Wang, Hiromichi Ebi, Takeshi Shimamura, Yan Liu, Tanya Tupper, Jing Ouyang, Jie Li, Peng Gao, Michele S. Woo, Chunxiao Xu, Masahiko Yanagita, Abigail Altabef, Shumei Wang, Charles Lee, Yuji Nakada, Christopher G. Peña, Yanping Sun, Yoko Franchetti, Catherine Yao, Amy Saur, Michael D. Cameron, Mizuki Nishino, D. Neil Hayes, Matthew D. Wilkerson, Patrick J. Roberts, Carrie B. Lee, Nabeel Bardeesy, Mohit Butaney, Lucian R. Chirieac, Daniel B. Costa, David Jackman, Norman E. Sharpless, Diego H. Castrillon, George D. Demetri, Pasi A. Jänne, Pier Paolo Pandolfi, Lewis C. Cantley, Andrew L. Kung, Jeffrey A. Engelman and Kwok-Kin Wong

The mechanism of OTUB1-mediated inhibition of ubiquitination pp. 618-622

Reuven Wiener, Xiangbin Zhang, Tao Wang and Cynthia Wolberger

The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response pp. 623-626

Takahito Sanada, Minsoo Kim, Hitomi Mimuro, Masato Suzuki, Michinaga Ogawa, Akiho Oyama, Hiroshi Ashida, Taira Kobayashi, Tomohiro Koyama, Shinya Nagai, Yuri Shibata, Jin Gohda, Jun-ichiro Inoue, Tsunehiro Mizushima and Chihiro Sasakawa

Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling pp. 627-631

Christoph Reinhardt, Mattias Bergentall, Thomas U. Greiner, Florence Schaffner, Gunnel Östergren-Lundén, Lars C. Petersen, Wolfram Ruf and Fredrik Bäckhed

Structure and mechanism of a glutamate–GABA antiporter pp. 632-636

Dan Ma, Peilong Lu, Chuangye Yan, Chao Fan, Ping Yin, Jiawei Wang and Yigong Shi

Epigenetics: Marked for success pp. 638-639

Heidi Ledford

A tough climb pp. 639-639

Andrew Peterman

Invisible pp. 642-642

João Ramalho-Santos

2012, volume 483, articles 7390

Change the approach to sustainable development pp. 375-375

Mark Stafford Smith

Activists ground primate flights pp. 381-382

Meredith Wadman

Opioid receptors revealed pp. 383-383

Lizzie Buchen

Indian budget disappoints pp. 384-384

K. S. Jayaraman

Clashing nations back SESAME pp. 385-385

Geoff Brumfiel

DNA donor rights affirmed pp. 387-387

Erika Check Hayden

Photonic chips made easier pp. 388-388

Katherine Bourzac

Mice guide human drug trial pp. 389-389

Heidi Ledford

Prehistoric proteins: Raising the dead pp. 390-393

Helen Pearson

Neuroscience: Making connections pp. 394-396

Jon Bardin

Observatories of the mind pp. 397-398

Christof Koch and R. Clay Reid

Think big for marine conservation pp. 399-399

Phil Weaver and David Johnson

A century of cosmic rays pp. 400-401

Michael Friedlander

Climate science: At the storm front pp. 402-403

Simon Lewis

Nutrition: Chew on this pp. 404-404

Anthony King

Q&A: The maths raconteur pp. 405-405

Jascha Hoffman

Mixed media policies of US federal agencies pp. 407-407

James G. Dickinson

China: A cultural shift for science pp. 407-407

Keqian Xu

China: Philosophers sparked good science pp. 407-407

Jianxin Su and Cheng Lu

Work together to crack wildlife trade pp. 407-407

Jacob Phelps, David P. Bickford and Edward L. Webb

Colorado methane study not clear–cut pp. 407-407

Kathleen M. Sgamma

Renato Dulbecco (1914–2012) pp. 408-408

Inder M. Verma

Life imperfectly imitates life pp. 410-411

David W. Pfennig and David W. Kikuchi

Swarming microtubules pp. 411-412

Tamás Vicsek

How to duplicate a DNA package pp. 412-413

Alysia Vandenberg and Geneviève Almouzni

Bubbles from the deep pp. 413-415

Henrik Svensen

Influenza's tale of tails pp. 416-417

Alexei L. Krasnoselsky and Michael G. Katze

Plasmons go quantum pp. 417-418

F. Javier García de Abajo

Trouble in the cell's powerhouse pp. 418-419

Derek P. Narendra and Richard J. Youle

Quantum plasmon resonances of individual metallic nanoparticles pp. 421-427

Jonathan A. Scholl, Ai Leen Koh and Jennifer A. Dionne

Suppression of the antiviral response by an influenza histone mimic pp. 428-433

Ivan Marazzi, Jessica S. Y. Ho, Jaehoon Kim, Balaji Manicassamy, Scott Dewell, Randy A. Albrecht, Chris W. Seibert, Uwe Schaefer, Kate L. Jeffrey, Rab K. Prinjha, Kevin Lee, Adolfo García-Sastre, Robert G. Roeder and Alexander Tarakhovsky

Intrinsic coupling of lagging-strand synthesis to chromatin assembly pp. 434-438

Duncan J. Smith and Iestyn Whitehouse

Resonant quantum transitions in trapped antihydrogen atoms pp. 439-443

C. Amole, M. D. Ashkezari, M. Baquero-Ruiz, W. Bertsche, P. D. Bowe, E. Butler, A. Capra, C. L. Cesar, M. Charlton, A. Deller, P. H. Donnan, S. Eriksson, J. Fajans, T. Friesen, M. C. Fujiwara, D. R. Gill, A. Gutierrez, J. S. Hangst, W. N. Hardy, M. E. Hayden, A. J. Humphries, C. A. Isaac, S. Jonsell, L. Kurchaninov, A. Little, N. Madsen, J. T. K. McKenna, S. Menary, S. C. Napoli, P. Nolan, K. Olchanski, A. Olin, P. Pusa, C. Ø. Rasmussen, F. Robicheaux, E. Sarid, C. R. Shields, D. M. Silveira, S. Stracka, C. So, R. I. Thompson, D. P. van der Werf and J. S. Wurtele

Electron tomography at 2.4-ångström resolution pp. 444-447

M. C. Scott, Chien-Chun Chen, Matthew Mecklenburg, Chun Zhu, Rui Xu, Peter Ercius, Ulrich Dahmen, B. C. Regan and Jianwei Miao

Large-scale vortex lattice emerging from collectively moving microtubules pp. 448-452

Yutaka Sumino, Ken H. Nagai, Yuji Shitaka, Dan Tanaka, Kenichi Yoshikawa, Hugues Chaté and Kazuhiro Oiwa

Collapse of polar ice sheets during the stage 11 interglacial pp. 453-456

Maureen E. Raymo and Jerry X. Mitrovica

Adaptive radiation of multituberculate mammals before the extinction of dinosaurs pp. 457-460

Gregory P. Wilson, Alistair R. Evans, Ian J. Corfe, Peter D. Smits, Mikael Fortelius and Jukka Jernvall

A comparative analysis of the evolution of imperfect mimicry pp. 461-464

Heather D. Penney, Christopher Hassall, Jeffrey H. Skevington, Kevin R. Abbott and Thomas N. Sherratt

MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons pp. 465-469

Jeremy N. Kay, Monica W. Chu and Joshua R. Sanes

Control of ground-state pluripotency by allelic regulation of Nanog pp. 470-473

Yusuke Miyanari and Maria-Elena Torres-Padilla

IDH mutation impairs histone demethylation and results in a block to cell differentiation pp. 474-478

Chao Lu, Patrick S. Ward, Gurpreet S. Kapoor, Dan Rohle, Sevin Turcan, Omar Abdel-Wahab, Christopher R. Edwards, Raya Khanin, Maria E. Figueroa, Ari Melnick, Kathryn E. Wellen, Donald M. O’Rourke, Shelley L. Berger, Timothy A. Chan, Ross L. Levine, Ingo K. Mellinghoff and Craig B. Thompson

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype pp. 479-483

Sevin Turcan, Daniel Rohle, Anuj Goenka, Logan A. Walsh, Fang Fang, Emrullah Yilmaz, Carl Campos, Armida W. M. Fabius, Chao Lu, Patrick S. Ward, Craig B. Thompson, Andrew Kaufman, Olga Guryanova, Ross Levine, Adriana Heguy, Agnes Viale, Luc G. T. Morris, Jason T. Huse, Ingo K. Mellinghoff and Timothy A. Chan

Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation pp. 484-488

Peppi Koivunen, Sungwoo Lee, Christopher G. Duncan, Giselle Lopez, Gang Lu, Shakti Ramkissoon, Julie A. Losman, Päivi Joensuu, Ulrich Bergmann, Stefan Gross, Jeremy Travins, Samuel Weiss, Ryan Looper, Keith L. Ligon, Roel G. W. Verhaak, Hai Yan and William G. Kaelin

Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å pp. 489-493

Zachary Lee Johnson, Cheom-Gil Cheong and Seok-Yong Lee

Identification and characterization of a bacterial hydrosulphide ion channel pp. 494-497

Bryan K. Czyzewski and Da-Neng Wang

Correction: Corrigendum: Functional complementation between FADD and RIP1 in embryos and lymphocytes pp. 498-498

Haibing Zhang, Xiaohui Zhou, Thomas McQuade, Jinghe Li, Francis Ka-Ming Chan and Jianke Zhang

Postdoc or not? pp. 499-500

Karen Kaplan

Turning point: Jessica Hellman pp. 501-501

Virginia Gewin

Visiting Bob pp. 504-504

John Gilbey

2012, volume 483, articles 7389

Graphene pp. S29-S29

Herb Brody

Materials science: Super carbon pp. S30-S31

Neil Savage

Production: Beyond sticky tape pp. S32-S33

Richard Van Noorden

Electronics: Back to analogue pp. S34-S36

Katherine Bourzac

Bioelectronics: The bionic material pp. S37-S37

Charles Schmidt

Come into the light pp. S38-S39

Neil Savage

Q&A: Taking charge pp. S40-S41

Tomás Palacios

Perspective: A means to an end pp. S42-S42

Rodney Ruoff

Material history: Learning from silicon pp. S43-S44

Michael Segal

Two nations divided by a common purpose pp. 247-247

Colin Macilwain

Putin promises science boost pp. 253-254

Quirin Schiermeier

Forecasters look back in time pp. 254-254

Jeff Tollefson

Spacecraft aims to expose violent hearts of galaxies pp. 255-255

Eric Hand

Water under pressure pp. 256-257

Natasha Gilbert

China’s budget backs science pp. 258-258

Jane Qiu

Japan fails to settle university dispute pp. 259-259

David Cyranoski

The split brain: A tale of two halves pp. 260-263

David Wolman

Plant biotechnology: Make it a decaf pp. 264-266

Brendan Borrell

Plug the real brain drain pp. 267-268

Martin E. Schwab and Anita D. Buchli

A plan for mental illness pp. 269-269

Thomas R. Insel, Barbara J. Sahakian, Valerie Voon, Jeffrey Nye, Verity J. Brown, Bruce M. Altevogt, Ed T. Bullmore, Guy M. Goodwin, Robert J. Howard, David J. Kupfer, Gavin Malloch, Hugh M. Marston, David J. Nutt, Trevor W. Robbins, Stephen Stahl, Mark D. Tricklebank and John H. Williams

Neuroscience: The mind mapped pp. 271-272

Robert Stickgold

Polar research: Deep-frozen science pp. 272-273

Francis Halzen

Q&A: The origami geometer pp. 274-274

Jascha Hoffman

Ads against chimp research criticized pp. 275-275

Joseph C. LaManna

Turing: Colossus computer revisited pp. 275-275

Henry Shipley

Turing: Brain model still incomplete pp. 275-275

David Dalrymple

Turing: Beyond the original concept pp. 275-275

Christopher Kanan

Be sparing with international laws pp. 275-275

Steven J. Hoffman and John-Arne Røttingen

Catalysis in tight spaces pp. 278-279

Noah Z. Burns and Eric N. Jacobsen

Inside story of ferroelectric memories pp. 279-280

Vincent Garcia and Manuel Bibes

A brainy background pp. 280-280

Henry Gee

Broken giant linked to heart failure pp. 281-282

Elizabeth M. McNally

A duo of graphene mimics pp. 282-284

Jonathan Simon and Markus Greiner

How brains learn to control machines pp. 284-285

David T. Blake

Favouring the unfavoured pp. 285-286

David E. Cane

Transcription initiation unwrapped pp. 286-287

Stephen Buratowski

Ancient deuterostome origins of vertebrate brain signalling centres pp. 289-294

Ariel M. Pani, Erin E. Mullarkey, Jochanan Aronowicz, Stavroula Assimacopoulos, Elizabeth A. Grove and Christopher J. Lowe

Genome-wide structure and organization of eukaryotic pre-initiation complexes pp. 295-301

Ho Sung Rhee and B. Franklin Pugh

Creating, moving and merging Dirac points with a Fermi gas in a tunable honeycomb lattice pp. 302-305

Leticia Tarruell, Daniel Greif, Thomas Uehlinger, Gregor Jotzu and Tilman Esslinger

Designer Dirac fermions and topological phases in molecular graphene pp. 306-310

Kenjiro K. Gomes, Warren Mar, Wonhee Ko, Francisco Guinea and Hari C. Manoharan

DNA-based self-assembly of chiral plasmonic nanostructures with tailored optical response pp. 311-314

Anton Kuzyk, Robert Schreiber, Zhiyuan Fan, Günther Pardatscher, Eva-Maria Roller, Alexander Högele, Friedrich C. Simmel, Alexander O. Govorov and Tim Liedl

Asymmetric spiroacetalization catalysed by confined Brønsted acids pp. 315-319

Ilija Čorić and Benjamin List

Uncovering the Neoproterozoic carbon cycle pp. 320-323

D. T. Johnston, F. A. Macdonald, B. C. Gill, P. F. Hoffman and D. P. Schrag

On the difficulty of increasing dental complexity pp. 324-327

Enni Harjunmaa, Aki Kallonen, Maria Voutilainen, Keijo Hämäläinen, Marja L. Mikkola and Jukka Jernvall

Coevolution in multidimensional trait space favours escape from parasites and pathogens pp. 328-330

R. Tucker Gilman, Scott L. Nuismer and Dwueng-Chwuan Jhwueng

Corticostriatal plasticity is necessary for learning intentional neuroprosthetic skills pp. 331-335

Aaron C. Koralek, Xin Jin, John D. Long, Rui M. Costa and Jose M. Carmena

Phase transitions in the assembly of multivalent signalling proteins pp. 336-340

Pilong Li, Sudeep Banjade, Hui-Chun Cheng, Soyeon Kim, Baoyu Chen, Liang Guo, Marc Llaguno, Javoris V. Hollingsworth, David S. King, Salman F. Banani, Paul S. Russo, Qiu-Xing Jiang, B. Tracy Nixon and Michael K. Rosen

A petunia ABC protein controls strigolactone-dependent symbiotic signalling and branching pp. 341-344

Tobias Kretzschmar, Wouter Kohlen, Joelle Sasse, Lorenzo Borghi, Markus Schlegel, Julien B. Bachelier, Didier Reinhardt, Ralph Bours, Harro J. Bouwmeester and Enrico Martinoia

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine pp. 345-349

Jeremiah R. McDole, Leroy W. Wheeler, Keely G. McDonald, Baomei Wang, Vjollca Konjufca, Kathryn A. Knoop, Rodney D. Newberry and Mark J. Miller

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human pp. 350-354

Atsuhiko Ichimura, Akira Hirasawa, Odile Poulain-Godefroy, Amélie Bonnefond, Takafumi Hara, Loïc Yengo, Ikuo Kimura, Audrey Leloire, Ning Liu, Keiko Iida, Hélène Choquet, Philippe Besnard, Cécile Lecoeur, Sidonie Vivequin, Kumiko Ayukawa, Masato Takeuchi, Kentaro Ozawa, Maithé Tauber, Claudio Maffeis, Anita Morandi, Raffaella Buzzetti, Paul Elliott, Anneli Pouta, Marjo-Riitta Jarvelin, Antje Körner, Wieland Kiess, Marie Pigeyre, Roberto Caiazzo, Wim Van Hul, Luc Van Gaal, Fritz Horber, Beverley Balkau, Claire Lévy-Marchal, Konstantinos Rouskas, Anastasia Kouvatsi, Johannes Hebebrand, Anke Hinney, Andre Scherag, François Pattou, David Meyre, Taka-aki Koshimizu, Isabelle Wolowczuk, Gozoh Tsujimoto and Philippe Froguel

Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis pp. 355-358

Kinya Hotta, Xi Chen, Robert S. Paton, Atsushi Minami, Hao Li, Kunchithapadam Swaminathan, Irimpan I. Mathews, Kenji Watanabe, Hideaki Oikawa, Kendall N. Houk and Chu-Young Kim

An oxygenase that forms and deoxygenates toxic epoxide pp. 359-362

Robin Teufel, Thorsten Friedrich and Georg Fuchs

Environment: Toxic effects pp. 363-365

Amanda Mascarelli

Turning point: Sean Bendall pp. 365-365

Virginia Gewin

The pi that wasn't round pp. 368-368

Dan Erlanson

2012, volume 483, articles 7388

Cuts hamper bid to tackle AIDS pp. 131-132

Erika Check Hayden

A solid case for Majorana fermions pp. 132-132

Eugenie Samuel Reich

Laser fusion nears crucial milestone pp. 133-134

Eric Hand

Trouble at the text mine pp. 134-135

Richard Van Noorden

Japan's nuclear crisis: Fukushima's legacy of fear pp. 138-140

Geoff Brumfiel and Ichiko Fuyuno

Rebuilding Japan: After the deluge pp. 141-143

David Cyranoski

Tsunami forecasting: The next wave pp. 144-146

Richard Monastersky

Putting seismic research to most effective use pp. 147-148

Hiroo Kanamori

Why giant earthquakes keep catching us out pp. 149-150

Thorne Lay

The nuclear landscape pp. 151-152

Peter Bradford

Energy: Plumbing the depths pp. 154-155

Amanda Mascarelli

Photography: Force of nature pp. 156-156

Stefan Michalowski and Georgia Smith

Q&A: Jazz experimentalist pp. 157-157

Jascha Hoffman

Step up funding for flu prevention pp. 158-158

Simon N. Williams

Keep jellyfish numbers in check pp. 158-158

Anthony J. Richardson, Daniel Pauly and Mark J. Gibbons

Clinical standards not practical in the lab pp. 158-158

Klaus Lindpaintner

Sugar: an excess of anything can harm pp. 158-158

Richard C. Cottrell

Human reproductive assistance pp. 160-161

Kim Hill and A. Magdalena Hurtado

Single molecules filmed dancing on a table top pp. 162-163

Misha Y. Ivanov

The sensation of stretch pp. 163-164

Philip A. Gottlieb and Frederick Sachs

Gorilla gorilla gorilla pp. 164-165

Richard A Gibbs and Jeffrey Rogers

A rusty carbon sink pp. 165-166

Tim I. Eglinton

Sorting out the sirtuins pp. 166-167

David B. Lombard and Richard A. Miller

Continuity through dispersity pp. 167-168

Richard A Register

Insights into hominid evolution from the gorilla genome sequence pp. 169-175

Aylwyn Scally, Julien Y. Dutheil, LaDeana W. Hillier, Gregory E. Jordan, Ian Goodhead, Javier Herrero, Asger Hobolth, Tuuli Lappalainen, Thomas Mailund, Tomas Marques-Bonet, Shane McCarthy, Stephen H. Montgomery, Petra C. Schwalie, Y. Amy Tang, Michelle C. Ward, Yali Xue, Bryndis Yngvadottir, Can Alkan, Lars N. Andersen, Qasim Ayub, Edward V. Ball, Kathryn Beal, Brenda J. Bradley, Yuan Chen, Chris M. Clee, Stephen Fitzgerald, Tina A. Graves, Yong Gu, Paul Heath, Andreas Heger, Emre Karakoc, Anja Kolb-Kokocinski, Gavin K. Laird, Gerton Lunter, Stephen Meader, Matthew Mort, James C. Mullikin, Kasper Munch, Timothy D. O’Connor, Andrew D. Phillips, Javier Prado-Martinez, Anthony S. Rogers, Saba Sajjadian, Dominic Schmidt, Katy Shaw, Jared T. Simpson, Peter D. Stenson, Daniel J. Turner, Linda Vigilant, Albert J. Vilella, Weldon Whitener, Baoli Zhu, David N. Cooper, Pieter de Jong, Emmanouil T. Dermitzakis, Evan E. Eichler, Paul Flicek, Nick Goldman, Nicholas I. Mundy, Zemin Ning, Duncan T. Odom, Chris P. Ponting, Michael A. Quail, Oliver A. Ryder, Stephen M. Searle, Wesley C. Warren, Richard K. Wilson, Mikkel H. Schierup, Jane Rogers, Chris Tyler-Smith and Richard Durbin

Piezo proteins are pore-forming subunits of mechanically activated channels pp. 176-181

Bertrand Coste, Bailong Xiao, Jose S. Santos, Ruhma Syeda, Jörg Grandl, Kathryn S. Spencer, Sung Eun Kim, Manuela Schmidt, Jayanti Mathur, Adrienne E. Dubin, Mauricio Montal and Ardem Patapoutian

Type VI secretion requires a dynamic contractile phage tail-like structure pp. 182-186

M. Basler, M. Pilhofer, G. P. Henderson, G. J. Jensen and J. J. Mekalanos

Experimental verification of Landauer’s principle linking information and thermodynamics pp. 187-189

Antoine Bérut, Artak Arakelyan, Artyom Petrosyan, Sergio Ciliberto, Raoul Dillenschneider and Eric Lutz

Field-driven photoemission from nanostructures quenches the quiver motion pp. 190-193

G. Herink, D. R. Solli, M. Gulde and C. Ropers

Imaging ultrafast molecular dynamics with laser-induced electron diffraction pp. 194-197

Cosmin I. Blaga, Junliang Xu, Anthony D. DiChiara, Emily Sistrunk, Kaikai Zhang, Pierre Agostini, Terry A. Miller, Louis F. DiMauro and C. D. Lin

Preservation of organic matter in sediments promoted by iron pp. 198-200

Karine Lalonde, Alfonso Mucci, Alexandre Ouellet and Yves Gélinas

Diverse transitional giant fleas from the Mesozoic era of China pp. 201-204

Diying Huang, Michael S. Engel, Chenyang Cai, Hao Wu and André Nel

Stability criteria for complex ecosystems pp. 205-208

Stefano Allesina and Si Tang

The role of Drosophila Piezo in mechanical nociception pp. 209-212

Sung Eun Kim, Bertrand Coste, Abhishek Chadha, Boaz Cook and Ardem Patapoutian

Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain pp. 213-217

Douglas J. Cook, Lucy Teves and Michael Tymianski

The sirtuin SIRT6 regulates lifespan in male mice pp. 218-221

Yariv Kanfi, Shoshana Naiman, Gail Amir, Victoria Peshti, Guy Zinman, Liat Nahum, Ziv Bar-Joseph and Haim Y. Cohen

An epigenetic blockade of cognitive functions in the neurodegenerating brain pp. 222-226

Johannes Gräff, Damien Rei, Ji-Song Guan, Wen-Yuan Wang, Jinsoo Seo, Krista M. Hennig, Thomas J. F. Nieland, Daniel M. Fass, Patricia F. Kao, Martin Kahn, Susan C. Su, Alireza Samiei, Nadine Joseph, Stephen J. Haggarty, Ivana Delalle and Li-Huei Tsai

Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity pp. 227-231

Xiaodong Jiang, Rachael A. Clark, Luzheng Liu, Amy J. Wagers, Robert C. Fuhlbrigge and Thomas S. Kupper

Correction: Corrigendum: The Amazon basin in transition pp. 232-232

Eric A. Davidson, Alessandro C. de Araújo, Paulo Artaxo, Jennifer K. Balch, I. Foster Brown, Mercedes M. C. Bustamante, Michael T. Coe, Ruth S. DeFries, Michael Keller, Marcos Longo, J. William Munger, Wilfrid Schroeder, Britaldo S. Soares-Filho, Carlos M. Souza and Steven C. Wofsy

Retirement: Sticking around pp. 233-235

Virginia Gewin

The postdoc dilemma pp. 235-235

Gaston Small

Bread pp. 238-238

Eliza Blair

2012, volume 483, articles 7387

Lenses on biology pp. S1-S1

Herb Brody and Ilona Miko

Cancer: Solving an age-old problem pp. S2-S6

Barbara Dunn

Clear up this fuzzy thinking on brain scans pp. 7-7

Olivier Oullier

Q&A: Controversy and intellect pp. S7-S7

Barbara Dunn

Synthetic Biology: Bits and pieces come to life pp. S8-S10

James Collins

Q&A: Circuit capacity pp. S11-S11

James Collins

Climate Change: A planet in flux pp. S12-S15

John P. Smol

Stem-cell therapy takes off in Texas pp. 13-14

David Cyranoski

Structural biologists share their toys pp. 15-16

Ewen Callaway

Protests delay Greek university reform pp. 15-15

Alison Abbott

Q&A: Regime change pp. S16-S16

John P. Smol

Egg-making stem cells found in adult ovaries pp. 16-16

Kendall Powell

Timing glitches dog neutrino claim pp. 17-17

Eugenie Samuel Reich

Ocean Science: The power of plankton pp. S17-S20

Paul Falkowski

Plans stall for biodefence lab pp. 18-19

Susan Young

US disease agency in fiscal peril pp. 19-19

Meredith Wadman

Rare diseases: Genomics, plain and simple pp. 20-22

Trisha Gura

Q&A: A slow-motion crisis pp. S21-S21

Paul Falkowski

Stem Cells: Flexible friends pp. S22-S26

Nirupama Shevde

Treating schizophrenia: Game on pp. 24-26

Erika Check Hayden

A clash of symbols pp. 27-28

Andrew Robinson

Q&A: Stemming the tide of misinformation pp. S27-S27

Nirupama Shevde

Four steps to avoid a synthetic-biology disaster pp. 29-29

Genya V. Dana, Todd Kuiken, David Rejeski and Allison A. Snow

Tax 'societal ills' to save the planet pp. 30-30

Edward Barbier

Computer science: Digital dawn pp. 32-33

Thomas Misa

Archaeology: Golden boy pp. 34-35

Jo Marchant

Theatre: Darkness made visible pp. 35-35

Daniel Cressey

Informed consent: cultural differences pp. 36-36

Gilles Guerrier, Didier Sicard and Paul T. Brey

Informed consent: meet patients' needs pp. 36-36

Silvio Garattini, Vittorio Bertele' and Rita Banzi

Citations: not all measures are equal pp. 36-36

Scott L. Hooper

Citations: results differ by database pp. 36-36

Carles Alcaraz and Sofia Morais

track illegal trade in wildlife pp. 36-36

Luís Felipe Toledo, Marianne V. Asmüssen and Jon Paul Rodríguez

In search of biosignatures pp. 38-39

Christoph U. Keller and Daphne M. Stam

Carrot or stick? pp. 39-40

Simon Gächter

In the shade of the oldest forest pp. 41-42

Brigitte Meyer-Berthaud and Anne-Laure Decombeix

Disguise gets a reaction pp. 42-43

Danielle M. Schultz and John P. Wolfe

Analog-to-digital drug screening pp. 43-44

Robert C. R. Wootton and Andrew J. deMello

Primed for resistance pp. 44-45

David B. Solit and Pasi A. Jänne

Gain control by layer six in cortical circuits of vision pp. 47-52

Shawn R. Olsen, Dante S. Bortone, Hillel Adesnik and Massimo Scanziani

Structural basis for iron piracy by pathogenic Neisseria pp. 53-58

Nicholas Noinaj, Nicole C. Easley, Muse Oke, Naoko Mizuno, James Gumbart, Evzen Boura, Ashley N. Steere, Olga Zak, Philip Aisen, Emad Tajkhorshid, Robert W. Evans, Andrew R. Gorringe, Anne B. Mason, Alasdair C. Steven and Susan K. Buchanan

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2 pp. 59-63

Anthony A. Armstrong, Firaz Mohideen and Christopher D. Lima

Biosignatures as revealed by spectropolarimetry of Earthshine pp. 64-66

Michael F. Sterzik, Stefano Bagnulo and Enric Palle

Re-emerging superconductivity at 48 kelvin in iron chalcogenides pp. 67-69

Liling Sun, Xiao-Jia Chen, Jing Guo, Peiwen Gao, Qing-Zhen Huang, Hangdong Wang, Minghu Fang, Xiaolong Chen, Genfu Chen, Qi Wu, Chao Zhang, Dachun Gu, Xiaoli Dong, Lin Wang, Ke Yang, Aiguo Li, Xi Dai, Ho-kwang Mao and Zhongxian Zhao

Catalytic functionalization of unactivated primary C–H bonds directed by an alcohol pp. 70-73

Eric M. Simmons and John F. Hartwig

Continental collision slowing due to viscous mantle lithosphere rather than topography pp. 74-77

Marin Kristen Clark

Surprisingly complex community discovered in the mid-Devonian fossil forest at Gilboa pp. 78-81

William E. Stein, Christopher M. Berry, Linda VanAller Hernick and Frank Mannolini

Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes pp. 82-86

Jennifer F. Hughes, Helen Skaletsky, Laura G. Brown, Tatyana Pyntikova, Tina Graves, Robert S. Fulton, Shannon Dugan, Yan Ding, Christian J. Buhay, Colin Kremitzki, Qiaoyan Wang, Hua Shen, Michael Holder, Donna Villasana, Lynne V. Nazareth, Andrew Cree, Laura Courtney, Joelle Veizer, Holland Kotkiewicz, Ting-Jan Cho, Natalia Koutseva, Steve Rozen, Donna M. Muzny, Wesley C. Warren, Richard A. Gibbs, Richard K. Wilson and David C. Page

Opposite effects of fear conditioning and extinction on dendritic spine remodelling pp. 87-91

Cora Sau Wan Lai, Thomas F. Franke and Wen-Biao Gan

Repetitive motor learning induces coordinated formation of clustered dendritic spines in vivo pp. 92-95

Min Fu, Xinzhu Yu, Ju Lu and Yi Zuo

Circadian rhythms govern cardiac repolarization and arrhythmogenesis pp. 96-99

Darwin Jeyaraj, Saptarsi M. Haldar, Xiaoping Wan, Mark D. McCauley, Jürgen A. Ripperger, Kun Hu, Yuan Lu, Betty L. Eapen, Nikunj Sharma, Eckhard Ficker, Michael J. Cutler, James Gulick, Atsushi Sanbe, Jeffrey Robbins, Sophie Demolombe, Roman V. Kondratov, Steven A. Shea, Urs Albrecht, Xander H. T. Wehrens, David S. Rosenbaum and Mukesh K. Jain

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR pp. 100-103

Anirudh Prahallad, Chong Sun, Sidong Huang, Federica Di Nicolantonio, Ramon Salazar, Davide Zecchin, Roderick L. Beijersbergen, Alberto Bardelli and René Bernards

Structural basis for recognition of H3K56-acetylated histone H3–H4 by the chaperone Rtt106 pp. 104-107

Dan Su, Qi Hu, Qing Li, James R. Thompson, Gaofeng Cui, Ahmed Fazly, Brian A. Davies, Maria Victoria Botuyan, Zhiguo Zhang and Georges Mer

Structural and functional conservation of key domains in InsP3 and ryanodine receptors pp. 108-112

Min-Duk Seo, Saroj Velamakanni, Noboru Ishiyama, Peter B. Stathopulos, Ana M. Rossi, Samir A. Khan, Philippa Dale, Congmin Li, James B. Ames, Mitsuhiko Ikura and Colin W. Taylor

Presentations: Billboard science pp. 113-115

Kendall Powell

Knowledge pp. 118-118

John Frizell