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2000, volume 404, articles 6781

Budget crisis forces hard choices on US high-energy physics pp. 909-910

Colin Macilwain

UK science spend ‘not sensible’ pp. 909-909

Natasha Loder

‘Saturation screen’ lets zebrafish show their stripes pp. 910-910

Peter Aldhous

Letter fuels South Africa's AIDS furore pp. 911-911

Michael Cherry

Unesco backs ‘science for debt’ plan pp. 911-911

David Dickson

Genetic diversity project fights for its life… pp. 912-912

Paul Smaglik

…as companies are urged to share benefits pp. 912-912

Paul Smaglik

NASA's new environmental satellite shows its sensitive side pp. 913-913

Tony Reichhardt

Japan gears up for growth in genomics pp. 913-913

Robert Triendl

New Zealand GM inquiry will cast a wide net pp. 914-915

Peter Pockley

German research agency ‘doesn't stifle creativity’, say 1,600 scientists pp. 915-915

Quirin Schiermeier

Meet the spin doctors … pp. 918-920

Philip Ball

Genetic modification and the meat market pp. 921-922

Jonathan Cowie

How diagnosis with microarrays can help cancer patients pp. 921-921

John R. W. Masters and Sunil R. Lakhani

Short-sighted move to close the 12-m telescope pp. 921-921

Ronak Shah

Distinguished scientists back Germany's DFG… pp. 922-922

Reinhard Jahn

…but young researchers feel disillusioned pp. 922-922

Daniel R. Dietrich and Bettina C. Hitzfeld

reply: …but young researchers feel disillusioned pp. 922-922

The Editor

‘Marketing’ species conservation pp. 923-924

R. E. Gullison, R. E. Rice and A. G. Blundell

Sir James in cyberspace pp. 925-926

Walter Gratzer

When silence is not a true option pp. 926-927

Sunetra Gupta

Of science and men pp. 927-928

Giovanni F. Bignami

Wacky star of the Renaissance pp. 928-929

Owen Gingerich

Not just a pretty Polly pp. 929-930

John C. Marshall

Communications from the dead pp. 930-931

A. J. Berry

On being human pp. 931-932

Andrew Whiten

The sequence of words pp. 932-933

Patrick V. Kirch

Evolution in a broader perspective pp. 933-933

Christophe Boesch

How much is really changing in Japan? pp. 934-934

Robert Triendl

Putting technology in its place pp. 935-935

Don Ihde

The Enduring Test pp. 937-937

Paul Levinson

Ringing in the new cosmology pp. 939-940

Wayne Hu

Introns gain ground pp. 940-943

Thomas H. Eickbush

Heat flow through nanobridges pp. 943-944

Leo P. Kouwenhoven and Liesbeth C. Venema

In reverse gear pp. 944-945

Gillian Bates

Molecular switches in lipid rafts pp. 945-947

Leslie A. Cary and Jonathan A. Cooper

Superconducting nanowires pp. 948-949

Gerd Schön

Decoy receptors thwart B cells pp. 949-950

Carl F. Ware

Danger! Men at work pp. 950-950

David Jones

Focusing hard X-rays with old LPs pp. 951-951

Björn Cederström, Robert N. Cahn, Mats Danielsson, Mats Lundqvist and David R. Nygren

Symbiotic solution to arsenic contamination pp. 951-952

J. M. Sharples, A. A. Meharg, S. M. Chambers and J. W. G. Cairney

Tunes and templates pp. 952-953

Willy Wong and Horace Barlow

A refugium for relicts? pp. 953-953

Makoto Manabe, Paul M. Barrett and Shinji Isaji

A flat Universe from high-resolution maps of the cosmic microwave background radiation pp. 955-959

P. de Bernardis, P. A. R. Ade, J. J. Bock, J. R. Bond, J. Borrill, A. Boscaleri, K. Coble, B. P. Crill, G. De Gasperis, P. C. Farese, P. G. Ferreira, K. Ganga, M. Giacometti, E. Hivon, V. V. Hristov, A. Iacoangeli, A. H. Jaffe, A. E. Lange, L. Martinis, S. Masi, P. V. Mason, P. D. Mauskopf, A. Melchiorri, L. Miglio, T. Montroy, C. B. Netterfield, E. Pascale, F. Piacentini, D. Pogosyan, S. Prunet, S. Rao, G. Romeo, J. E. Ruhl, F. Scaramuzzi, D. Sforna and N. Vittorio

Structure of the reovirus core at 3.6?Å resolution pp. 960-967

Karin M. Reinisch, Max L. Nibert and Stephen C. Harrison

Identification of molecular-cloud material in interplanetary dust particles pp. 968-971

Scott Messenger

Quantum suppression of superconductivity in ultrathin nanowires pp. 971-974

A. Bezryadin, C. N. Lau and M. Tinkham

Measurement of the quantum of thermal conductance pp. 974-977

K. Schwab, E. A. Henriksen, J. M. Worlock and M. L. Roukes

Coulomb-blockade transport in single-crystal organic thin-film transistors pp. 977-980

W. A. Schoonveld, J. Wildeman, D. Fichou, P. A. Bobbert, B. J. van Wees and T. M. Klapwijk

Inorganic yellow-red pigments without toxic metals pp. 980-982

M. Jansen and H. P. Letschert

A homochiral metal–organic porous material for enantioselective separation and catalysis pp. 982-986

Jung Soo Seo, Dongmok Whang, Hyoyoung Lee, Sung Im Jun, Jinho Oh, Young Jin Jeon and Kimoon Kim

Recycled oceanic crust observed in ‘ghost plagioclase’ within the source of Mauna Loa lavas pp. 986-990

Alexander V. Sobolev, Albrecht W. Hofmann and Igor K. Nikogosian

Human population in the biodiversity hotspots pp. 990-992

Richard P. Cincotta, Jennifer Wisnewski and Robert Engelman

Identification of sleep-promoting neurons in vitro pp. 992-995

Thierry Gallopin, Patrice Fort, Emmanuel Eggermann, Bruno Cauli, Pierre-Hervé Luppi, Jean Rossier, Etienne Audinat, Michel Mühlethaler and Mauro Serafin

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease pp. 995-999

Jane A. Gross, Janet Johnston, Sherri Mudri, Rachel Enselman, Stacey R. Dillon, Karen Madden, Wenfeng Xu, Julia Parrish-Novak, Don Foster, Cathy Lofton-Day, Margaret Moore, Alisa Littau, Angelika Grossman, Harald Haugen, Kevin Foley, Hal Blumberg, Kim Harrison, Wayne Kindsvogel and Christopher H. Clegg

Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases pp. 999-1003

Masahiro Kawabuchi, Yoshinori Satomi, Toshifumi Takao, Yasutsugu Shimonishi, Shigeyuki Nada, Katsuya Nagai, Alexander Tarakhovsky and Masato Okada

CpG methylation is maintained in human cancer cells lacking DNMT1 pp. 1003-1007

Ina Rhee, Kam-Wing Jair, Ray-Whay Chiu Yen, Christoph Lengauer, James G. Herman, Kenneth W. Kinzler, Bert Vogelstein, Stephen B. Baylin and Kornel E. Schuebel

Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins pp. 1007-1011

Laurent Blanchoin, Kurt J. Amann, Henry N. Higgs, Jean-Baptiste Marchand, Donald A. Kaiser and Thomas D. Pollard

Low fidelity DNA synthesis by human DNA polymerase-η pp. 1011-1013

Toshiro Matsuda, Katarzyna Bebenek, Chikahide Masutani, Fumio Hanaoka and Thomas A. Kunkel

Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis pp. 1014-1018

Mengjia Tang, Phuong Pham, Xuan Shen, John-Stephen Taylor, Mike O'Donnell, Roger Woodgate and Myron F. Goodman

Retrotransposition of a bacterial group II intron pp. 1018-1021

Benoit Cousineau, Stacey Lawrence, Dorie Smith and Marlene Belfort

2000, volume 404, articles 6780

Clean-up strategy at Australian nuclear site called into question pp. 797-797

Peter Pockley

UK defence research goes private pp. 797-797

Peter Aldhous

Middle East's synchrotron heads for Jordan pp. 798-798

Heather McCabe

Top physicist crosses to Boston in search of like minds pp. 798-798

Steve Nadis

Critics blast US missile defence system as flawed pp. 799-799

Colin Macilwain

California targets GM-trial vandals with new legislation pp. 799-799

Sally Lehrmann

Congress moves to open up access for foreign academics pp. 800-800

Tony Reichhardt

Women and ethnic minorities needed for US skills gap… pp. 800-800

Meredith Wadman

…as academic pay fails to keep up pp. 800-800

Rex Dalton

A first in computer printing pp. 801-801

Natasha Loder

US energy agency sequences human chromosome trio pp. 801-801

Paul Smaglik

Bid to relax rules on tissue transport runs into opposition pp. 801-801

Michael Cherry

Wellcome shoulders its share of blame for Oxford debacle pp. 802-802

Natasha Loder

Politicians seek to block human-gene patents in Europe pp. 802-802

Alison Abbott and Ulrike Hellerer

A silence that speaks volumes pp. 804-808

Trisha Gura

Open-source work even more vital to genome project than to software pp. 809-809

Andreas P. Russ, Samuel A. J. R. Aparicio and Mark B. L. Carlton

Mayo and the mouse pp. 809-809

Steven G. Younkin and Susan Stoddard

Science rules — OK? pp. 811-812

John Ziman

Advances in a toxic offensive pp. 812-813

Alastair Hay

Ecological Scrabble played in earnest pp. 813-814

Jeffrey A. Harvey

Turned out nice again pp. 814-814

Mojib Latif

Mighty mice pp. 815-815

Michael F.W. Festing and Elizabeth M.C. Fisher

The paradigm and the pendulum pp. 817-817

William K. Hartmann

Respiration in the balance pp. 819-820

John Grace and Mark Rayment

Seeing in the sound zone pp. 820-821

Michael Merzenich

Oxide-ion conductors by design pp. 821-823

John B. Goodenough

New guardians of the genome pp. 823-824

David B. Roth and Martin Gellert

A moving experience pp. 825-827

Kevin Fox

High tension pp. 827-827

David Jones

William Donald Hamilton (1936–2000) pp. 828-828

Robert Trivers

Small bodies of the Solar System pp. 829-832

Don Yeomans

Euler's disk and its finite-time singularity pp. 833-834

H. K. Moffatt

Potential modulations along carbon nanotubes pp. 834-835

Sander J. Tans and Cees Dekker

Microbial essentials at hydrothermal vents pp. 835-835

Anna-Louise Reysenbach, Amy B. Banta, David R. Boone, Stephen C. Cary and George W. Luther

Rainforest fragmentation kills big trees pp. 836-836

William F. Laurance, Patricia Delamônica, Susan G. Laurance, Heraldo L. Vasconcelos and Thomas E. Lovejoy

Turbulent convection at very high Rayleigh numbers pp. 837-840

J. J. Niemela, L. Skrbek, K. R. Sreenivasan and R. J. Donnelly

Induction of visual orientation modules in auditory cortex pp. 841-847

Jitendra Sharma, Alessandra Angelucci and Mriganka Sur

Extended magnetic reconnection at the Earth's magnetopause from detection of bi-directional jets pp. 848-850

T. D. Phan, L. M. Kistler, B. Klecker, G. Haerendel, G. Paschmann, B. U. Ö. Sonnerup, W. Baumjohann, M. B. Bavassano-Cattaneo, C. W. Carlson, A. M. DiLellis, K.-H. Fornacon, L. A. Frank, M. Fujimoto, E. Georgescu, S. Kokubun, E. Moebius, T. Mukai, M. Øieroset, W. R. Paterson and H. Reme

Statistical signatures of photon localization pp. 850-853

A. A. Chabanov, M. Stoytchev and A. Z. Genack

Spontaneous macroscopic magnetization at the superconducting transition temperature of YBa2Cu3O7-δ pp. 853-855

R. Carmi, E. Polturak, G. Koren and A. Auerbach

Designing fast oxide-ion conductors based on La2Mo2O9 pp. 856-858

Philippe Lacorre, François Goutenoire, Odile Bohnke, Richard Retoux and Yvon Laligant

Evidence that decomposition rates of organic carbon in mineral soil do not vary with temperature pp. 858-861

Christian P. Giardina and Michael G. Ryan

Respiration as the main determinant of carbon balance in European forests pp. 861-865

R. Valentini, G. Matteucci, A. J. Dolman, E.-D. Schulze, C. Rebmann, E. J. Moors, A. Granier, P. Gross, N. O. Jensen, K. Pilegaard, A. Lindroth, A. Grelle, C. Bernhofer, T. Grünwald, M. Aubinet, R. Ceulemans, A. S. Kowalski, T. Vesala, Ü. Rannik, P. Berbigier, D. Loustau, J. Guðmundsson, H. Thorgeirsson, A. Ibrom, K. Morgenstern, R. Clement, J. Moncrieff, L. Montagnani, S. Minerbi and P. G. Jarvis

Determination of relative growth rates of natural quartz crystals pp. 865-869

Phillip D. Ihinger and Stephen I. Zink

Insurance-based advantage to helpers in a tropical hover wasp pp. 869-871

Jeremy Field, Gavin Shreeves, Seirian Sumner and Maurizio Casiraghi

Visual behaviour mediated by retinal projections directed to the auditory pathway pp. 871-876

Laurie von Melchner, Sarah L. Pallas and Mriganka Sur

Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo pp. 876-881

Balazs Lendvai, Edward A. Stern, Brian Chen and Karel Svoboda

Ion permeation mechanism of the potassium channel pp. 881-884

Johan Åqvist and Victor Luzhkov

CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection pp. 884-888

D. Branch Moody, Timo Ulrichs, Walter Mühlecker, David C. Young, Sudagar S. Gurcha, Ethan Grant, Jean-Pierre Rosat, Michael B. Brenner, Catherine E. Costello, Gurdyal S. Besra and Steven A. Porcelli

Integration of floral inductive signals in Arabidopsis pp. 889-892

Miguel A. Blázquez and Detlef Weigel

Role of NF-κB in p53-mediated programmed cell death pp. 892-897

Kevin M. Ryan, Mary K. Ernst, Nancy R. Rice and Karen H. Vousden

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development pp. 897-900

Yijie Gao, David O. Ferguson, Wei Xie, John P. Manis, JoAnn Sekiguchi, Karen M. Frank, Jayanta Chaudhuri, James Horner, Ronald A. DePinho and Frederick W. Alt

Single-molecule analysis of DNA uncoiling by a type II topoisomerase pp. 901-904

Terence R. Strick, Vincent Croquette and David Bensimon

Erratum: Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages pp. 904-904

Célio G. Freire- de-Lima, Danielle O. Nascimento, Milena B. P. Soares, Patricia T. Bozza, Hugo C. Castro-Faria-Neto, Fernando G. de Mello, George A. DosReis and Marcela F. Lopes

Erratum: Formation of molecular gas in the tidal debris of violent galaxy–galaxy interactions pp. 904-904

Jonathan Braine, Ute Lisenfeld, Pierre-Alain Duc and Stéphane Leon

Correction: The DNA sequence of human chromosome 22 pp. 904-904

I. Dunham, N. Shimizu, B. A. Roe and S. Chissoe

Correction: Tribosphenic mammal from the North American Early Cretaceous pp. 904-904

Richard L. Cifelli

2000, volume 404, articles 6779

Critics challenge Celera's claims over human genome sequence… pp. 691-692

Paul Smaglik

…as biotech debate splits along party lines pp. 691-691

Paul Smaglik

German parliament agrees on limits to bioethics inquiry pp. 692-692

Quirin Schiermeier and Ulrike Hellerer

Ontario joins the genomics goldrush pp. 692-692

David Spurgeon

US academy study finds GM foods are safe… pp. 693-693

Colin Macilwain

…but critics claim the panel was biased pp. 693-693

Colin Macilwain

Music software to come to genome aid? pp. 694-694

Declan Butler

Space detectors show off their paces pp. 694-694

Tony Reichhardt

Frustration grows over EU grant application procedures pp. 695-695

Alison Abbott and Patrick Weydt

Deaths bring South African HIV drug trials to a premature halt pp. 695-695

Michael Cherry

Director of Wellcome centre resigns over damning report pp. 696-696

Natasha Loder

Fake bird fossil highlights the problem of illegal trading pp. 696-696

Rex Dalton

Affymetrix loses first round of patent battle pp. 697-697

David Dickson

UK ethicists back use of stem cells pp. 697-697

David Dickson

Storming the Tower of Babel pp. 700-700

Henry Bortman and Philip Ball

Technology failures were caused by managers not listening to engineers pp. 701-701

Richard Wilson

No conflict between SLAC and Japan's KEK pp. 701-701

Helen Quinn

reply: No conflict between SLAC and Japan's KEK pp. 701-701

Colin Macilwain

More than meets the eye pp. 703-704

Philip Ball

Seeds that never grew in Sweden pp. 704-705

Harriet Ritvo

Endangered harvest? pp. 704-704

John G. Robinson and John Thorbjarnarson

An uncertainty principle for geometry pp. 705-706

Peter T. Landsberg

A fraternal view of Russian fauna pp. 706-706

Mikhail Mina

Venture funding for new ideas pp. 707-707

Jayant V. Narlikar

Regenesis pp. 708-708

Cynthia Ward

Perfect use of imperfection pp. 709-710

Hansjörg Schild and Hans-Georg Rammensee

Chaos in space and time pp. 710-711

J. P. Gollub and M. C. Cross

Shattering developments pp. 711-713

Günter Theißen

Stripes defeat the Fermi liquid pp. 714-715

J. Zaanen

An arresting tale pp. 714-714

Bernd Pulverer

Recognizing DNA in the library pp. 715-717

Satish K. Nair and Stephen K. Burley

The stellar fuel pp. 717-717

Leslie Sage

Freezing by heating pp. 718-719

H. Eugene Stanley

Commit ye helpers pp. 719-720

Anne O'Garra

Rain, rain, go away pp. 720-720

David Jones

Delaying the onset of Huntington's in mice pp. 721-722

Anton van Dellen, Colin Blakemore, Robert Deacon, Denis York and Anthony J. Hannan

Hexadecane decay by methanogenesis pp. 722-723

Robert T. Anderson and Derek R. Lovley

Parasitic honeybees get royal treatment pp. 723-723

Madeleine Beekman, Johan N. M. Calis and Willem Jan Boot

Specificities of heparan sulphate proteoglycans in developmental processes pp. 725-728

Norbert Perrimon and Merton Bernfield

One-dimensional nature of the magnetic fluctuations in YBa2Cu 3O6.6 pp. 729-731

H. A. Mook, Pengcheng Dai, F. Dogan and R. D. Hunt

Magnetic field surrounding the starburst nucleus of the galaxy M82 from polarized dust emission pp. 732-733

J. S. Greaves, W. S. Holland, T. Jenness and T. G. Hawarden

Mechanisms of extensive spatiotemporal chaos in Rayleigh–Bénard convection pp. 733-736

David A. Egolf, Ilarion V. Melnikov, Werner Pesch and Robert E. Ecke

Phase transitions in the incoherent lattice fluctuations in YBa 2Cu3O7-δ pp. 736-740

R. P. Sharma, S. B. Ogale, Z. H. Zhang, J. R. Liu, W. K. Chu, Boyed Veal, A. Paulikas, H. Zheng and T. Venkatesan

Complete photonic bandgaps in 12-fold symmetric quasicrystals pp. 740-743

M. E. Zoorob, M. D. B. Charlton, G. J. Parker, J. J. Baumberg and M. C. Netti

Manipulation of atoms across a surface at room temperature pp. 743-745

T. W. Fishlock, A. Oral, R. G. Egdell and J. B. Pethica

Self-assembly of nanoparticles into structured spherical and network aggregates pp. 746-748

Andrew K. Boal, Faysal Ilhan, Jason E. DeRouchey, Thomas Thurn-Albrecht, Thomas P. Russell and Vincent M. Rotello

Subduction erosion along the Middle America convergent margin pp. 748-752

C. R. Ranero and R. von Huene

Quantitative evidence for global amphibian population declines pp. 752-755

Jeff. E. Houlahan, C. Scott Findlay, Benedikt R. Schmidt, Andrea H. Meyer and Sergius L. Kuzmin

The metapopulation capacity of a fragmented landscape pp. 755-758

Ilkka Hanski and Otso Ovaskainen

Asymmetric redirection of flow through the heart pp. 759-761

Philip J. Kilner, Guang-Zhong Yang, A. John Wilkes, Raad H. Mohiaddin, David N. Firmin and Magdi H. Yacoub

Interruption of a basal ganglia–forebrain circuit prevents plasticity of learned vocalizations pp. 762-766

Michael S. Brainard and Allison J. Doupe

SHATTERPROOF MADS-box genes control seed dispersal in Arabidopsis pp. 766-770

Sarah J. Liljegren, Gary S. Ditta, Yuval Eshed, Beth Savidge, John L. Bowman and Martin F. Yanofsky

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes pp. 770-774

Ulrich Schubert, Luis C. Antón, James Gibbs, Christopher C. Norbury, Jonathan W. Yewdell and Jack R. Bennink

The major substrates for TAP in vivo are derived from newly synthesized proteins pp. 774-778

Eric A. J. Reits, Jan C. Vos, Monique Grommé and Jacques Neefjes

NAK is an IκB kinase-activating kinase pp. 778-782

Yuichiro Tojima, Atsushi Fujimoto, Mireille Delhase, Yi Chen, Shigetsugu Hatakeyama, Kei-ichi Nakayama, Yoko Kaneko, Yuji Nimura, Noboru Motoyama, Kyoji Ikeda, Michael Karin and Makoto Nakanishi

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1 pp. 782-787

René H. Medema, Geert J. P. L. Kops, Johannes L. Bos and Boudewijn M. T. Burgering

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage pp. 787-790

Takeshi Nishikawa, Diane Edelstein, Xue Liang Du, Sho-ichi Yamagishi, Takeshi Matsumura, Yasufumi Kaneda, Mark A. Yorek, David Beebe, Peter J. Oates, Hans-Peter Hammes, Ida Giardino and Michael Brownlee

Georgia realizes the commercial potential of science pp. 794-794

Brendan Horton

2000, volume 404, articles 6778

Complaints grow over delays in UK animal licence processing pp. 529-530

Natasha Loder

Japan sets tissue donor guidelines pp. 529-529

Robert Triendl

Varmus tells Congress to grasp thorny policy issues pp. 530-530

Paul Smaglik

US geneticists encouraged to play by the book pp. 530-530

Meredith Wadman

Japan squares up to conservationists over grey whale's status pp. 531-532

Asako Saegusa

Global warming could be bad news for Arctic ozone layer pp. 531-531

Peter Aldhous

US court tests the breadth of patent protection on proteins pp. 532-532

Meredith Wadman

Baja peninsula claims five victims in tragic accident pp. 533-533

Rex Dalton and David Cyranoski

Reshuffle lifts French synchrotron hopes pp. 533-533

Heather McCabe

Cereal gene bank accepts need for patents… pp. 534-534

Rex Dalton

… as Monsanto makes rice genome public pp. 534-534

Declan Butler and Peter Pockley

Is NASA paying the price of a dash for Mars? pp. 535-535

Tony Reichhardt

Whatever happened to leptin? pp. 538-540

Marina Chicurel

Assessment mismatches must be sorted out: they leave species at risk pp. 541-541

Craig Hilton-Taylor, Georgina M. Mace, David R. Capper, Nigel J. Collar, Simon N. Stuart, Colin J. Bibby, Caroline Pollock and Jørgen B. Thomsen

Fooled, but not foolish pp. 541-541

William L. Allen

How much use is the Human Genome Project? pp. 541-542

Sol Hadden

Genes: we can't expect full understanding yet pp. 542-542

Bruce Alberts and Aaron Klug

Garlic study vindicated by official investigation pp. 542-542

J. Koscielny, R. Schmitt, H. Radtke, R. Latza and H. Kiesewetter

Learn lateral thinking first and specialize later pp. 542-542

Nicholas J. Kuhn

Religion has its place but don't pretend it's science pp. 542-542

Lewis Wolpert

Tracking down a lethal inhalation pp. 543-544

Ed Regis

An education for climatologists pp. 544-544

Robert E. Livezey

Reviving the Doctor Universalis pp. 544-545

Cynthia M. Pyle

Something for everyone pp. 545-546

Joan Roughgarden

Science in culture pp. 546-546

Martin Kemp

Abstraction and idealism pp. 547-547

Semir Zeki

The new laureate speaks pp. 549-549

Charles Sheffield

When Greenland ice melts pp. 551-552

Christine Schøtt Hvidberg

The good taste of genomics pp. 552-553

Stuart Firestein

The water cooler pp. 555-555

Jim Gillon

Bacterial cheaters pp. 555-556

Joan E. Strassmann

A new spin on magnets pp. 556-557

Thomas F. Rosenbaum

Dendrites go up, axons go down pp. 557-559

Stephen M. Strittmatter

British birds by number pp. 559-560

Robert M. May

A new check on issuing the licence pp. 560-561

J. Julian Blow and Shusuke Tada

Two for the price of one pp. 561-561

Sarah Tomlin

The sharper image pp. 561-561

David Jones

George Ledyard Stebbins (1906–2000) pp. 562-562

Vassiliki Betty Smocovitis

Payment for labour in monkeys pp. 563-563

Frans B. M. de Waal and Michelle L. Berger

Sex and the single lichen pp. 564-564

G. J. Murtagh, P. S. Dyer and P. D. Crittenden

Non-haemolytic β-amino-acid oligomers pp. 565-565

Emilie A. Porter, Xifang Wang, Hee-Seung Lee, Bernard Weisblum and Samuel H. Gellman

Stomach rinsing in rays pp. 566-566

David W. Sims, Paul L. R. Andrews and J. Z. Young

Semaphorin 3A is a chemoattractant for cortical apical dendrites pp. 567-573

Franck Polleux, Theresa Morrow and Anirvan Ghosh

Identification of comet Hyakutake's extremely long ion tail from magnetic field signatures pp. 574-576

Geraint H. Jones, André Balogh and Timothy S. Horbury

Interception of comet Hyakutake's ion tail at a distance of 500 million kilometres pp. 576-578

G. Gloeckler, J. Geiss, N. A. Schwadron, L. A. Fisk, T. H. Zurbuchen, F. M. Ipavich, R. von Steiger, H. Balsiger and B. Wilken

A scalable quantum computer with ions in an array of microtraps pp. 579-581

J. I. Cirac and P. Zoller

Magnetoresistance from quantum interference effects in ferromagnets pp. 581-584

N. Manyala, Y. Sidis, J. F. DiTusa, G. Aeppli, D.P. Young and Z. Fisk

Communication at millimetre–submillimetre wavelengths using a ceramic ribbon pp. 584-588

C. Yeh, F. Shimabukuro, P. Stanton, V. Jamnejad, W. Imbriale and F. Manshadi

Functional hydrogel structures for autonomous flow control inside microfluidic channels pp. 588-590

David J. Beebe, Jeffrey S. Moore, Joseph M. Bauer, Qing Yu, Robin H. Liu, Chelladurai Devadoss and Byung-Ho Jo

Substantial contribution to sea-level rise during the last interglacial from the Greenland ice sheet pp. 591-594

Kurt M. Cuffey and Shawn J. Marshall

Rapid and early export of Phaeocystis antarctica blooms in the Ross Sea, Antarctica pp. 595-598

G. R. DiTullio, J. M. Grebmeier, K. R. Arrigo, M. P. Lizotte, D. H. Robinson, A. Leventer, J. P. Barry, M. L. VanWoert and R. B. Dunbar

Developmental cheating in the social bacterium Myxococcus xanthus pp. 598-601

Gregory J. Velicer, Lee Kroos and Richard E. Lenski

A family of candidate taste receptors in human and mouse pp. 601-604

Hiroaki Matsunami, Jean-Pierre Montmayeur and Linda B. Buck

High mobility of proteins in the mammalian cell nucleus pp. 604-609

Robert D. Phair and Tom Misteli

PAR3 is a cofactor for PAR4 activation by thrombin pp. 609-613

Mayumi Nakanishi-Matsui, Yao-Wu Zheng, David J. Sulciner, Ethan J. Weiss, Matthew J. Ludeman and Shaun R. Coughlin

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway pp. 613-617

Dae-Sik Lim, Seong-Tae Kim, Bo Xu, Richard S. Maser, Junyu Lin, John H.J. Petrini and Michael B. Kastan

Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity pp. 617-621

Elisabetta Bianchi, Simona Denti, Alessandra Granata, Giovanna Bossi, Jens Geginat, Antonello Villa, Lars Rogge and Ruggero Pardi

XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis pp. 622-625

Domenico Maiorano, Jacques Moreau and Marcel Méchali

The Cdt1 protein is required to license DNA for replication in fission yeast pp. 625-628

Hideo Nishitani, Zoi Lygerou, Takeharu Nishimoto and Paul Nurse

erratum: Benzodiazepine actions mediated by specific γ-aminobutyric acidA receptor subtypes pp. 629-629

Uwe Rudolph, Florence Crestani, Dietmar Benke, Ina Brünig, Jack A. Benson, Jean-Marc Fritschy, James R. Martin, Horst Bluethmann and Hanns Möhler

Correction: Observation of a square flux-line lattice in the unconventional superconductor Sr2RuO4 pp. 629-629

T. M. Riseman, P. G. Kealey, E. M. Forgan, A. P. Mackenzie, L. M. Galvin, A. W. Tyler, S. L. Lee, C. Ager, D. McK. Paul, C. M. Aegerter, R. Cubitt, Z. Q. Mao, T. Akima and Y. Maeno

Obesity pp. 631-631

Philip Campbell and Ritu Dhand

Obesity in the new millennium pp. 632-634

J. M. Friedman

Obesity as a medical problem pp. 635-643

Peter G. Kopelman

Genetics of body-weight regulation pp. 644-651

Gregory S. Barsh, I. Sadaf Farooqi and Stephen O'Rahilly

Towards a molecular understanding of adaptive thermogenesis pp. 652-660

Bradford B. Lowell and Bruce M. Spiegelman

Central nervous system control of food intake pp. 661-671

Michael W. Schwartz, Stephen C. Woods, Daniel Porte, Randy J. Seeley and Denis G. Baskin

Medicinal strategies in the treatment of obesity pp. 672-677

George A. Bray and Louis A. Tartaglia

Roche and Obesity pp. 678-679

Jonathan K.C. Knowles

Next-generation biologists must straddle computation and biology pp. 683-684

Potter Wickware

Multiple-degree dynamics pp. 683-683

Potter Wickware

Companies of all sizes are prospecting for proteins pp. 684-685

Helen Gavaghan

The power of prediction pp. 685-685

Potter Wickware

United States gives priority to skills shortage pp. 686-687

Potter Wickware

Europe seeks solution to bioinformatics shortfall pp. 687-688

Helen Gavaghan

Borrowing methods and models pp. 687-687

Potter Wickware

2000, volume 404, articles 6777

Safety concerns force NASA to condemn satellite to fiery end pp. 423-423

Tony Reichhardt

Software error ‘caused Mars lander crash’ pp. 423-423

Tony Reichhardt

German researchers seek legal backing for stem cell work pp. 424-424

Alison Abbott

Balance is returning after US biotechnology shares scare pp. 424-424

Meredith Wadman

Radical changes urged for Spanish universities pp. 425-426

Xavier Bosch

The worm's turn to claim Internet fame pp. 425-425

Declan Butler

Modified reforms end two years of deadlock at CNRS pp. 426-426

Heather McCabe

Giant tortoises come home pp. 426-426

Natasha Loder

Is starting simple the path to complexity? pp. 427-427

Paul Smaglik

India and US bring collaboration out of the freezer pp. 427-427

K. S. Jayaraman

Chemists ‘volunteered for nerve gas tests’ pp. 428-429

Natasha Loder

Cuts may force cancellation of Austrian research grants pp. 429-429

Quirin Schiermeier

Local farmers would be able to feed Africa if they were given the chance pp. 431-431

Willy H. Verhye

Ancient Chinese had their fingers on the pulse pp. 431-431

P.-L. Chau

No pie in the sky, thanks pp. 431-431

Brian Charlesworth

Scientist, social reformer, soldier, spy pp. 433-433

John Meurig Thomas

Before the great binary divide pp. 434-435

Bruce Mazlish

Fingering the brain's past pp. 434-434

Ian Glynn

Ill-served inventions pp. 435-436

David Jones

A view of figures through the ages pp. 436-436

Ludmilla Jordanova

The Big Bang and the genetic code pp. 437-437

Gino Segrè

Eternal verities, eternal questions pp. 439-439

Ben Bova

Survival of the clearest pp. 441-442

Steven Pinker

A view of Mount Drosophila pp. 442-443

Jonathan Hodgkin

Peeking into the obscured Universe pp. 443-445

Günther Hasinger

Bats about the Arctic pp. 446-447

Peter D. Moore

Doubly magic nickel pp. 447-449

Philip Walker

Not just an active site pp. 449-450

David W. Banner

A new twist to an old story pp. 450-451

George Pickett

ABC of meningococcal diversity pp. 451-452

Ian M. Feavers

Backyard exotica pp. 452-453

Frank Wilczek

Neanderthal population genetics pp. 453-454

Matthias Höss

Direct illumination pp. 454-454

David Jones

Finger-length ratios and sexual orientation pp. 455-456

Terrance J. Williams, Michelle E. Pepitone, Scott E. Christensen, Bradley M. Cooke, Andrew D. Huberman, Nicholas J. Breedlove, Tessa J. Breedlove, Cynthia L. Jordan and S. Marc Breedlove

A unique circadian-rhythm photoreceptor pp. 456-457

Patrick Emery, Ralf Stanewsky, Jeffrey C. Hall and Michael Rosbash

Colour mixing in wing scales of a butterfly pp. 457-457

P. Vukusic, J. R. Sambles and C. R. Lawrence

Resolving the extragalactic hard X-ray background pp. 459-464

R. F. Mushotzky, L. L. Cowie, A. J. Barger and K. A. Arnaud

Peptide exosite inhibitors of factor VIIa as anticoagulants pp. 465-470

Mark S. Dennis, Charles Eigenbrot, Nicholas J. Skelton, Mark H. Ultsch, Lydia Santell, Mary A. Dwyer, Mark P. O'Connell and Robert A. Lazarus

Double-quantum vortex in superfluid 3He-A pp. 471-473

R. Blaauwgeers, V. B. Eltsov, M. Krusius, J. J. Ruohio, R. Schanen and G. E. Volovik

Imaging of localized electronic states in the quantum Hall regime pp. 473-476

N. B. Zhitenev, T. A. Fulton, A. Yacoby, H. F. Hess, L. N. Pfeiffer and K. W. West

Anisotropic spinodal dewetting as a route to self-assembly of patterned surfaces pp. 476-478

A. M. Higgins and R. A. L. Jones

A soluble and air-stable organic semiconductor with high electron mobility pp. 478-481

H. E. Katz, A. J. Lovinger, J. Johnson, C. Kloc, T. Siegrist, W. Li, Y.-Y. Lin and A. Dodabalapur

Molecular-scale interface engineering for polymer light-emitting diodes pp. 481-484

Peter K. H. Ho, Ji-Seon Kim, Jeremy H. Burroughes, Heinrich Becker, Sam F. Y. Li, Thomas M. Brown, Franco Cacialli and Richard H. Friend

Effect of climate change relative to ozone depletion on UV exposure in subarctic lakes pp. 484-487

Reinhard Pienitz and Warwick F. Vincent

Hf–Nd isotope evidence for a transient dynamic regime in the early terrestrial mantle pp. 488-490

Francis Albarède, Janne Blichert-Toft, Jeffrey D. Vervoort, James D. Gleason and Minik Rosing

Molecular analysis of Neanderthal DNA from the northern Caucasus pp. 490-493

Igor V. Ovchinnikov, Anders Götherström, Galina P. Romanova, Vitaliy M. Kharitonov, Kerstin Lidén and William Goodwin

Pervasive density-dependent recruitment enhances seedling diversity in a tropical forest pp. 493-495

Kyle E. Harms, S. Joseph Wright, Osvaldo Calderón, Andrés Hernández and Edward Allen Herre

The evolution of syntactic communication pp. 495-498

Martin A. Nowak, Joshua B. Plotkin and Vincent A. A. Jansen

Glutamate spillover suppresses inhibition by activating presynaptic mGluRs pp. 498-502

Simon J. Mitchell and R. Angus Silver

Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491 pp. 502-506

J. Parkhill, M. Achtman, K. D. James, S. D. Bentley, C. Churcher, S. R. Klee, G. Morelli, D. Basham, D. Brown, T. Chillingworth, R. M. Davies, P. Davis, K. Devlin, T. Feltwell, N. Hamlin, S. Holroyd, K. Jagels, S. Leather, S. Moule, K. Mungall, M. A. Quail, M.-A. Rajandream, K. M. Rutherford, M. Simmonds, J. Skelton, S. Whitehead, B. G. Spratt and B. G. Barrell

The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate pp. 506-510

Koji Yasutomo, Carolyn Doyle, Lucio Miele and Ronald N. Germain

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation pp. 510-514

Michael J. Difilippantonio, Jie Zhu, Hua Tang Chen, Eric Meffre, Michel C. Nussenzweig, Edward E. Max, Thomas Ried and André Nussenzweig

Yeast Sm-like proteins function in mRNA decapping and decay pp. 515-518

Sundaresan Tharun, Weihai He, Andrew E. Mayes, Pascal Lennertz, Jean D. Beggs and Roy Parker

Structural basis for the anticoagulant activity of the thrombin–thrombomodulin complex pp. 518-525

Pablo Fuentes-Prior, Yoriko Iwanaga, Robert Huber, Rene Pagila, Galina Rumennik, Marian Seto, John Morser, David R. Light and Wolfram Bode

Correction: The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites pp. 525-525

Brian Hendrich, Ulrike Hardeland, Huck-Hui Ng, Josef Jiricny and Adrian Bird

Erratum: DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination pp. 525-525

Clifford D. Mol, Tadahide Izumi, Sankar Mitra and John A. Tainer

2000, volume 404, articles 6776

Researchers caught in dispute over transgenic mice patents pp. 319-320

Rex Dalton

Iridium crash relieves astronomers pp. 319-319

Alison Abbott

Computer glitch unleashes prize nomination debate pp. 320-320

Steve Nadis

Japan's cloning ban will still allow stem cell experiments pp. 321-321

Robert Triendl

Space researchers protest at ‘disruptive’ export controls pp. 321-321

Tony Reichhardt

Car maker joins exodus from anti-Kyoto coalition pp. 322-322

Meredith Wadman

Could AIDS treatments slip through patents loophole? pp. 322-322

Paul Smaglik

Israeli R&D grants ‘too restrictive’ pp. 322-322

Haim Watzman

Northern lobby attacks UK synchrotron siting pp. 323-323

Natasha Loder

French minister feels the heat over Soleil pp. 323-323

Heather McCabe

Japan may place gene research on summit agenda pp. 324-324

Asako Saegusa

US/UK statement on genome data prompts debate on ‘free access’ pp. 324-325

Declan Butler

The human genome itself must be freely available to all humankind pp. 325-325

Bruce Alberts and Sir Aaron Klug

To create generalists, teach students how to learn by themselves pp. 329-329

Philippe Baveye

We have touched the dust from dying stars pp. 329-329

Donald D. Clayton

Confusion over cash for Indian biotech centre… pp. 329-329

V. S. Chauhan

… though funding states have promised to pay up pp. 329-330

Arturo Falaschi

The lasting value of Mitchell's mechanisms pp. 330-330

John Prebble

People must be judged in the context of their time pp. 330-330

Ulrich Wobus and Ingo Schubert

reply: … though funding states have promised to pay up pp. 330-330

K.S. Jayaraman

reply: People must be judged in the context of their time pp. 330-330

Susanne Heim

The imperial slaughterhouse pp. 331-332

Roy Porter

A meteorologist's nightmare pp. 332-333

Howard B. Bluestein

Palaeobiology in mammoth form pp. 333-334

Michael J. Benton

Science in culture pp. 334-334

Martin Kemp

Brains, courage and integrity pp. 335-335

Tom Gehrels

Bordeaux Mixture pp. 337-337

Charles Dexter Ward

From forelimbs to two legs pp. 339-340

Mark Collard and Leslie C. Aiello

Tricks with a single photon pp. 340-341

Peter Zoller

Parkinson's pathology in a fly pp. 341-343

Christian Haass and Philipp J. Kahle

A needle in a cosmic haystack pp. 344-345

Isabelle A. Grenier

Making hard light sharper pp. 345-347

Roland Smith

Changing partners pp. 347-348

Chavela M. Carr and Peter J. Novick

Rafting vesicle pp. 348-348

Amanda Tromans

Natural cunning pp. 349-349

David Jones

Robert Rathbun Wilson (1914–2000) pp. 350-350

Alvin V. Tollestrup

Y-chromosome variation and Irish origins pp. 351-352

Emmeline W. Hill, Mark A. Jobling and Daniel G. Bradley

Apolipoprotein E and cognitive performance pp. 352-354

Jacob Raber, Derek Wong, Gui-Qiu Yu, Manuel Buttini, Robert W. Mahley, Robert E. Pitas and Lennart Mucke

Fluctuations caught in the act pp. 352-352

Lars K. Nielsen, Thomas Bjørnholm and Ole G. Mouritsen

A tetrodotoxin-producing marine pathogen pp. 354-354

Kim B. Ritchie, Ivan Nagelkerken, Sara James and Garriet W. Smith

Three-dimensional structure of the neuronal-Sec1–syntaxin 1a complex pp. 355-362

Kira M. S. Misura, Richard H. Scheller and William I. Weis

Discovery of a new population of high-energy γ-ray sources in the Milky Way pp. 363-365

N. Gehrels, D. J. Macomb, D. L. Bertsch, D. J. Thompson and R. C. Hartman

Trapping an atom with single photons pp. 365-368

P. W. H. Pinkse, T. Fischer, P. Maunz and G. Rempe

An algorithmic benchmark for quantum information processing pp. 368-370

E. Knill, R. Laflamme, R. Martinez and C.-H. Tseng

Storage of X-ray photons in a crystal resonator pp. 371-373

K.-D. Liss, R. Hock, M. Gomm, B. Waibel, A. Magerl, M. Krisch and R. Tucoulou

Soft-mode hardening in SrTiO3 thin films pp. 373-376

A. A. Sirenko, C. Bernhard, A. Golnik, Anna M. Clark, Jianhua Hao, Weidong Si and X. X. Xi

Extended surface chirality from supramolecular assemblies of adsorbed chiral molecules pp. 376-379

M. Ortega Lorenzo, C. J. Baddeley, C. Muryn and R. Raval

Bonding and reactivity at oxide mineral surfaces from model aqueous complexes pp. 379-382

Brian L. Phillips, William H. Casey and Magnus Karlsson

Evidence that humans evolved from a knuckle-walking ancestor pp. 382-385

Brian G. Richmond and David S. Strait

Predictive accuracy of population viability analysis in conservation biology pp. 385-387

Barry W. Brook, Julian J. O'Grady, Andrew P. Chapman, Mark A. Burgman, H. Resit Akçakaya and Richard Frankham

Low variability in a Y-linked plant gene and its implications for Y-chromosome evolution pp. 388-390

Dmitry A. Filatov, Françoise Monéger, Ioan Negrutiu and Deborah Charlesworth

Representation of a perceptual decision in developing oculomotor commands pp. 390-394

Joshua I. Gold and Michael N. Shadlen

A Drosophila model of Parkinson's disease pp. 394-398

Mel B. Feany and Welcome W. Bender

Interleukin-1 polymorphisms associated with increased risk of gastric cancer pp. 398-402

Emad M. El-Omar, Mary Carrington, Wong-Ho Chow, Kenneth E. L. McColl, Jay H. Bream, Howard A. Young, Jesus Herrera, Jolanta Lissowska, Chiu-Chin Yuan, Nathaniel Rothman, George Lanyon, Maureen Martin, Joseph F. Fraumeni and Charles S. Rabkin

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes pp. 402-407

Zuoming Sun, Christopher W. Arendt, Wilfried Ellmeier, Edward M. Schaeffer, Mary Jean Sunshine, Leena Gandhi, Justin Annes, Daniela Petrzilka, Abraham Kupfer, Pamela L. Schwartzberg and Dan R. Littman

Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1 pp. 407-411

Long Gu, Susan Tseng, Renée M. Horner, Carmen Tam, Massimo Loda and Barrett J. Rollins

Betaglycan binds inhibin and can mediate functional antagonism of activin signalling pp. 411-414

Kathy A. Lewis, Peter C. Gray, Amy L. Blount, Leigh A. MacConell, Ezra Wiater, Louise M. Bilezikjian and Wylie Vale

The Gcn5 bromodomain co-ordinates nucleosome remodelling pp. 414-417

Popi Syntichaki, Irene Topalidou and George Thireos

2000, volume 404, articles 6775

Europe joins race to turn the Internet into one vast computer pp. 213-213

Declan Butler

Uproar at Oxford as suspended professor returns to work pp. 214-214

Natasha Loder

Homegrown computer roots out phylogenetic networks pp. 214-214

Henry Gee

Irish researchers divided over how to spend huge new fund pp. 215-215

Alison Abbott

Protests force primate farm to close pp. 215-215

Peter Aldhous

NEON to shed light on environment research pp. 216-216

Rex Dalton

Are AIDS dissidents advising South Africa? pp. 216-216

Michael Cherry

German research agency stifles creativity pp. 217-217

Quirin Schiermeier and Patrick Weydt

EU centres saved from ‘catastrophe’ pp. 217-218

Natasha Loder

New form of hydrogen power provokes scepticism pp. 218-218

Tony Reichhardt

Art imitating high-energy physics pp. 219-219

Alison Abbott

Older women scientists fight USGS over layoffs pp. 219-219

Rex Dalton

There's enough food for everyone, but the poor can't afford to buy it pp. 222-222

Jonathan R. Latham

Spanish university study ignores research pp. 222-222

Jorge Mira-Pérez

Not too late to apologize pp. 222-222

Bernd Wirsing

DoE still involved in the Human Genome Project pp. 222-222

James F. Decker

Questions suspended in the ether pp. 223-224

David Hyder and Heinz Lübbig

Igniting interest in a broad readership pp. 224-225

William I. Rose

Sewage, motorists and more pp. 224-224

Henry Petroski

A century of physical endeavour pp. 225-226

Graham Farmelo

Science in culture pp. 226-226

Taketo Mizota, Mickey Zdravkovich, Kai-U. Graw and Alfred Leder

A 1,000-year chain of thinkers pp. 227-227

Giovanni F. Bignami

Reality check pp. 229-229

David Brin

Push-button entanglement pp. 231-232

Rainer Blatt

Pathogen-driven forest diversity pp. 232-233

Wim H. van der Putten

Hopes for a flame-free future pp. 233-235

Kevin Kendall

Transparent talk pp. 237-237

Karen Southwell

In search of the whales' sisters pp. 237-239

Zhexi Luo

Laser light splits atom pp. 239-239

Donald Umstadter

The element of uncertainty pp. 240-241

Russell J. Hemley

Reeling CASK into the nucleus pp. 241-242

David S. Bredt

Electric flight pp. 242-242

David Jones

Growth of carbon micro-trees pp. 243-243

P. M. Ajayan, J. M. Nugent, R. W. Siegel, B. Wei and Ph. Kohler-Redlich

Scaling in athletic world records pp. 244-244

Sandra Savaglio and Vincenzo Carbone

Gene silencing in worms and fungi pp. 245-245

Caterina Catalanotto, Gianluca Azzalin, Giuseppe Macino and Carlo Cogoni

Quantum information and computation pp. 247-255

Charles H. Bennett and David P. DiVincenzo

Experimental entanglement of four particles pp. 256-259

C. A. Sackett, D. Kielpinski, B. E. King, C. Langer, V. Meyer, C. J. Myatt, M. Rowe, Q. A. Turchette, W. M. Itano, D. J. Wineland and C. Monroe

Quantum distribution of protons in solid molecular hydrogen at megabar pressures pp. 259-262

Hikaru Kitamura, Shinji Tsuneyuki, Tadashi Ogitsu and Takashi Miyake

Towards the clarity limit in optical fibre pp. 262-264

Gordon A. Thomas, Boris I. Shraiman, Paul F. Glodis and Michael J. Stephen

Direct oxidation of hydrocarbons in a solid-oxide fuel cell pp. 265-267

Seungdoo Park, John M. Vohs and Raymond J. Gorte

Single crystals of an ionic anthracene aggregate with a triplet ground state pp. 267-269

H. Bock, K. Gharagozloo-Hubmann, M. Sievert, T. Prisner and Z. Havlas

Seismic hazard in the Marmara Sea region following the 17 August 1999 Izmit earthquake pp. 269-273

Aurélia Hubert-Ferrari, Aykut Barka, Eric Jacques, Süleyman S. Nalbant, Bertrand Meyer, Rolando Armijo, Paul Tapponnier and Geoffrey C. P. King

Fine-scale heterogeneity in the Earth's inner core pp. 273-275

John E. Vidale and Paul S. Earle

The oldest known anthropoid postcranial fossils and the early evolution of higher primates pp. 276-278

Daniel L. Gebo, Marian Dagosto, K. Christopher Beard, Tao Qi and Jingwen Wang

Soil pathogens and spatial patterns of seedling mortality in a temperate tree pp. 278-281

Alissa Packer and Keith Clay

The ecological cost of sex pp. 281-285

C. Patrick Doncaster, Graeme E. Pound and Simon J. Cox

NMDA spikes in basal dendrites of cortical pyramidal neurons pp. 285-289

Jackie Schiller, Guy Major, Helmut J. Koester and Yitzhak Schiller

The Ras-MAPK pathway is important for olfaction in Caenorhabditis elegans pp. 289-293

Takaaki Hirotsu, Satoshi Saeki, Masayuki Yamamoto and Yuichi Iino

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells pp. 293-296

Scott M. Hammond, Emily Bernstein, David Beach and Gregory J. Hannon

A genetic link between co-suppression and RNA interference in C. elegans pp. 296-298

René F. Ketting and Ronald H. A. Plasterk

Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2 pp. 298-302

Yi-Ping Hsueh, Ting-Fang Wang, Fu-Chia Yang and Morgan Sheng

Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA pp. 302-307

Raul Mendez, Laura E. Hake, Thorkell Andresson, Laurie E. Littlepage, Joan V. Ruderman and Joel D. Richter

The structure of malaria pigment β-haematin pp. 307-310

Silvina Pagola, Peter W. Stephens, D. Scott Bohle, Andrew D. Kosar and Sara K. Madsen

Pushing the frontiers of interdisciplinary research: an idea whose time has come pp. 313-315

Diane Gershon

Changing the face of training for science at the interface pp. 315-316

Diane Gershon

Crossing the divide between theory and practice pp. 316-316

Diane Gershon

2000, volume 404, articles 6774

Genome leaders told to keep their eyes on the main prize pp. 111-111

Paul Smaglik

Revamped GenBank offers extra data links pp. 111-111

Paul Smaglik

GM debate must go global, says meeting… pp. 112-112

David Dickson

… and calls for openness and transparency pp. 112-112

David Dickson

Unesco ‘worse than I imagined,’ says new director pp. 113-113

Natasha Loder

China looks to west for economic growth pp. 113-113

Tian Xuewen

Geneticists oppose consent ruling pp. 114-115

Meredith Wadman

Expensive space crystal programme has produced little of scientific value, says panel pp. 114-114

Tony Reichhardt

$350m gift boosts MIT brain power pp. 115-116

Steve Nadis

Panel will seek ‘appropriate’ AIDS goals for South Africa pp. 115-115

Michael Cherry

Indian research budget favours defence pp. 116-116

K. S. Jayaraman

Rival demands sink genome alliance plans pp. 117-117

Natasha Loder

Biology back issues free as publishers walk HighWire pp. 117-117

Declan Butler

Why private institutions alone will not do enough to protect biodiversity pp. 120-120

Alexander James, Kevin J. Gaston and Andrew Balmford

Alzheimer's research is vital in work on ageing pp. 120-120

Joseph M. Erwin

Opportunism knocks? pp. 120-120

Ingo Schubert and Ulrich Wobus

Rape as an adaptation pp. 121-122

Jerry A. Coyne and Andrew Berry

Amassing the case for the defence pp. 122-123

Douglas Palmer

Unfinished portrait of the artist pp. 123-124

John Nash

Science's stall in the global market-place pp. 124-124

Norman Myers

A century of cognitive decline pp. 125-125

Bruce A. Yankner

The song of the Neanderthal pp. 127-127

Mark W. Tiedemann

Life's downs and ups pp. 129-130

Douglas Erwin

Schrödinger's sheep pp. 130-131

Wojciech H. Zurek

A chorus line pp. 131-133

Emilio Salinas and Ranulfo Romo

Too hot to melt pp. 134-135

A. Lindsay Greer

Moving in mysterious ways pp. 135-137

Alison M. Condliffe and Phillip T. Hawkins

Pushing electrons around pp. 137-138

Mark Ratner

Love is not puffed up pp. 138-138

Amanda Tromans

The Antarctic connection pp. 139-140

Richard G. Gordon

Expiry date guaranteed pp. 140-140

David Jones

Urban benzene and population exposure pp. 141-142

Vincenzo Cocheo, Paolo Sacco, Caterina Boaretto, Emile De Saeger, Pascual Perez Ballesta, Henrik Skov, Eddy Goelen, Norbert Gonzalez and Antonia Baeza Caracena

Climate variability and North Sea cod pp. 142-142

Carl M. O'Brien, Clive J. Fox, Benjamin Planque and John Casey

Bleaching patterns in reef corals pp. 142-143

B. E. Brown, R. P. Dunne, M. S. Goodson and A. E. Douglas

Myopia and ambient night-time lighting pp. 143-144

Karla Zadnik, Lisa A. Jones, Brett C. Irvin, Robert N. Kleinstein, Ruth E. Manny, Julie A. Shin and Donald O. Mutti

Myopia and ambient night-time lighting pp. 144-144

J. Gwiazda, E. Ong, R. Held and F. Thorn

reply: Myopia and ambient night-time lighting pp. 144-144

Richard A. Stone, Maureen G. Maguire and Graham E. Quinn

Cenozoic motion between East and West Antarctica pp. 145-150

Steven C. Cande, Joann M. Stock, R. Dietmar Müller and Takemi Ishihara

Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein pp. 151-158

Annette S. Kim, Lazaros T. Kakalis, Norzehan Abdul-Manan, Grace A. Liu and Michael K. Rosen

Discovery of calcium in Mercury's atmosphere pp. 159-161

Thomas A. Bida, Rosemary M. Killen and Thomas H. Morgan

North–south geological differences between the residual polar caps on Mars pp. 161-164

P. C. Thomas, M. C. Malin, K. S. Edgett, M. H. Carr, W. K. Hartmann, A. P. Ingersoll, P. B. James, L. A. Soderblom, J. Veverka and R. Sullivan

Impossibility of deleting an unknown quantum state pp. 164-165

Arun Kumar Pati and Samuel L. Braunstein

Molecular control over Au/GaAs diodes pp. 166-168

Ayelet Vilan, Abraham Shanzer and David Cahen

Sintering dense nanocrystalline ceramics without final-stage grain growth pp. 168-171

I.-Wei Chen and X.-H. Wang

The influence of Antarctic sea ice on glacial–interglacial CO2 variations pp. 171-174

Britton B. Stephens and Ralph F. Keeling

Interferometric radar measurements of water level changes on the Amazon flood plain pp. 174-177

Douglas E. Alsdorf, John M. Melack, Thomas Dunne, Leal A. K. Mertes, Laura L. Hess and Laurence C. Smith

Delayed biological recovery from extinctions throughout the fossil record pp. 177-180

James W. Kirchner and Anne Weil

Simple rules yield complex food webs pp. 180-183

Richard J. Williams and Neo D. Martinez

Inhibitory threshold for critical-period activation in primary visual cortex pp. 183-186

Michela Fagiolini and Takao K. Hensch

Attention modulates synchronized neuronal firing in primate somatosensory cortex pp. 187-190

P. N. Steinmetz, A. Roy, P. J. Fitzgerald, S. S. Hsiao, K. O. Johnson and E. Niebur

Growth patterns in the developing brain detected by using continuum mechanical tensor maps pp. 190-193

Paul M. Thompson, Jay N. Giedd, Roger P. Woods, David MacDonald, Alan C. Evans and Arthur W. Toga

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages pp. 193-197

Koichi Akashi, David Traver, Toshihiro Miyamoto and Irving L. Weissman

Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Iβ pp. 197-201

Jens Schlossmann, Aldo Ammendola, Keith Ashman, Xiangang Zong, Andrea Huber, Gitte Neubauer, Ge-Xin Wang, Hans-Dieter Allescher, Michael Korth, Matthias Wilm, Franz Hofmann and Peter Ruth

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response pp. 201-204

Jong-Soo Lee, Kimberly M. Collins, Alexandra L. Brown, Chang-Hun Lee and Jay H. Chung

Ligand binding and conformational motions in myoglobin pp. 205-208

Andreas Ostermann, Robert Waschipky, Fritz G. Parak and G. Ulrich Nienhaus

2000, volume 404, articles 6773

Germany challenges human stem cell patent awarded ‘by mistake’ pp. 3-4

Quirin Schiermeier

UK university recruitment in danger pp. 3-3

Natasha Loder

US energy agency pulls plug on role in genome project pp. 4-4

Colin Macilwain

Australian jailed for removal of fossilized footprints pp. 4-4

Peter Pockley

Culling plans put future of red deer study in jeopardy pp. 5-6

Natasha Loder

NIH tightens up monitoring of gene-therapy mishaps pp. 5-5

Paul Smaglik

Young, worldly and unhelpful all miss out on data sharing pp. 6-6

Rex Dalton

US eases Israelis' lab access pp. 6-6

Haim Watzman

Promega and Roche take up battle over PCR patents pp. 7-7

Rex Dalton

Funding woes spell doom for US radio dish pp. 7-7

Tony Reichhardt

Canadian budget boost for science pp. 8-8

David Spurgeon

Post-Cold War needs ‘new forms of scientific linkage’ pp. 8-8

Heather McCabe

Analysis of polio vaccine could end dispute over how AIDS originated pp. 9-9

Declan Butler

Crowded universities cramp more than just students' style pp. 13-13

Akio Yamamoto

Patent confusion in law on new plant varieties pp. 13-13

John R. Porter

Evolution rising from the grave pp. 15-16

Michael A. Goldman

Around the world via Greenwich pp. 16-17

J.L. Heilbron

A window on scientific progress pp. 17-18

Gunhard Æ. Oravas

Science in culture pp. 18-18

John Whitfield

Reversing Rorschach pp. 19-19

Richard Gregory

Danger — hard hack area pp. 21-21

Paul McAuley

Of ice and elephants pp. 23-24

Daniel P. Schrag

p53 sends nucleotides to repair DNA pp. 24-25

Guillermina Lozano and Stephen J. Elledge

Heartfelt enlightenment pp. 25-27

Ueli Schibler

Brane new worlds pp. 28-29

Jerome Gauntlett

Imaging in the fourth dimension pp. 29-31

Thomas Elbert and Andreas Keil

Beauty is ova-rated pp. 31-31

Rachel Smyly

Brimstone on Mars pp. 32-32

Harry Y. McSween

Brief lives pp. 32-32

David Jones

Errors in judging ‘offside’ in football pp. 33-33

Raôul R. D. Oudejans, Raymond Verheijen, Frank C. Bakker, Jeroen C. Gerrits, Marten Steinbrückner and Peter J. Beek

Finding genes in Plasmodium falciparum pp. 34-34

Mihaela Pertea, Steven L. Salzberg and Malcolm J. Gardner

Finding genes in Plasmodium falciparum pp. 34-35

Dan Lawson, Sharen Bowman and Bart Barrell

Fish do not avoid survey vessels pp. 35-36

P. G. Fernandes, A. S. Brierley, E. J. Simmonds, N. W. Millard, S. D. McPhail, F. Armstrong, P. Stevenson and M. Squires

Migration and speciation pp. 36-36

Kevin Winker

The importance of repairing stalled replication forks pp. 37-41

Michael M. Cox, Myron F. Goodman, Kenneth N. Kreuzer, David J. Sherratt, Steven J. Sandler and Kenneth J. Marians

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage pp. 42-49

Hiroshi Tanaka, Hirofumi Arakawa, Tatsuya Yamaguchi, Kenji Shiraishi, Seisuke Fukuda, Kuniko Matsui, Yoshiki Takei and Yusuke Nakamura

Evidence of atmospheric sulphur in the martian regolith from sulphur isotopes in meteorites pp. 50-52

James Farquhar, Joel Savarino, Terri L. Jackson and Mark H. Thiemens

Fabrication of photonic crystals for the visible spectrum by holographic lithography pp. 53-56

M. Campbell, D. N. Sharp, M. T. Harrison, R. G. Denning and A. J. Turberfield

Electrophoretic assembly of colloidal crystals with optically tunable micropatterns pp. 56-59

R. C. Hayward, D. A. Saville and I. A. Aksay

Shape control of CdSe nanocrystals pp. 59-61

Xiaogang Peng, Liberato Manna, Weidong Yang, Juanita Wickham, Erik Scher, Andreas Kadavanich and A. P. Alivisatos

Evidence from U–Th dating against Northern Hemisphere forcing of the penultimate deglaciation pp. 61-66

Gideon M. Henderson and Niall C. Slowey

Stable sulphate clusters as a source of new atmospheric particles pp. 66-69

Markku Kulmala, Liisa Pirjola and Jyrki M. Mäkelä

Geodetic evidence for a low slip rate in the Altyn Tagh fault system pp. 69-72

Rebecca Bendick, Roger Bilham, Jeffrey Freymueller, Kristine Larson and Guanghua Yin

Tree species impoverishment and the future flora of the Atlantic forest of northeast Brazil pp. 72-74

José Maria Cardoso da Silva and Marcelo Tabarelli

Egg investment is influenced by male attractiveness in the mallard pp. 74-77

Emma J. A. Cunningham and Andrew F. Russell

Macaque monkeys categorize images by their ordinal number pp. 77-80

Tanya Orlov, Volodya Yakovlev, Shaul Hochstein and Ehud Zohary

Temporal patterns of human cortical activity reflect tone sequence structure pp. 80-84

Aniruddh D. Patel and Evan Balaban

Cannabinoids control spasticity and tremor in a multiple sclerosis model pp. 84-87

David Baker, Gareth Pryce, J. Ludovic Croxford, Peter Brown, Roger G. Pertwee, John W. Huffman and Lorna Layward

Light acts directly on organs and cells in culture to set the vertebrate circadian clock pp. 87-91

David Whitmore, Nicholas S. Foulkes and Paolo Sassone-Corsi

Delayed activation of the paternal genome during seed development pp. 91-94

Jean-Philippe Vielle-Calzada, Ramamurthy Baskar and Ueli Grossniklaus

Eomesodermin is required for mouse trophoblast development and mesoderm formation pp. 95-99

Andreas P. Russ, Sigrid Wattler, William H. Colledge, Samuel A. J. R. Aparicio, Mark B. L. Carlton, Jonathan J. Pearce, Sheila C. Barton, M. Azim Surani, Kenneth Ryan, Michael C. Nehls, Valerie Wilson and Martin J. Evans

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours pp. 99-103

Annie Yang, Nancy Walker, Roderick Bronson, Mourad Kaghad, Mariette Oosterwegel, Jacques Bonnin, Christine Vagner, Helene Bonnet, Pieter Dikkes, Arlene Sharpe, Frank McKeon and Daniel Caput

Single-molecule studies of the effect of template tension on T7 DNA polymerase activity pp. 103-106

Gijs J.L. Wuite, Steven B. Smith, Mark Young, David Keller and Carlos Bustamante