Koch's postulates fulfilled for SARS virus

Ron A. M. Fouchier (), Thijs Kuiken, Martin Schutten, Geert van Amerongen, Gerard J. J. van Doornum, Bernadette G. van den Hoogen, Malik Peiris, Wilina Lim, Klaus Stöhr and Albert D. M. E. Osterhaus
Additional contact information
Ron A. M. Fouchier: Erasmus Medical Centre
Thijs Kuiken: Erasmus Medical Centre
Martin Schutten: Erasmus Medical Centre
Geert van Amerongen: Erasmus Medical Centre
Gerard J. J. van Doornum: Erasmus Medical Centre
Bernadette G. van den Hoogen: Erasmus Medical Centre
Malik Peiris: University of Hong Kong, University Pathology Building, Queen Mary Hospital
Wilina Lim: Government Virus Unit, 9/F Public Health Laboratory Centre
Albert D. M. E. Osterhaus: Erasmus Medical Centre

Nature, 2003, vol. 423, issue 6937, 240-240

Abstract: Abstract Severe acute respiratory syndrome (SARS) has recently emerged as a new human disease, resulting globally in 435 deaths from 6,234 probable cases (as of 3 May 2003). Here we provide proof from experimental infection of cynomolgus macaques (Macaca fascicularis) that the newly discovered SARS-associated coronavirus (SCV) is the aetiological agent of this disease. Our understanding of the aetiology of SARS will expedite the development of diagnostic tests, antiviral therapies and vaccines, and may allow a more concise case definition for this emerging disease.

Date: 2003
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DOI: 10.1038/423240a

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