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2015, volume 521, articles 7553

Eat insects for fun, not to help the environment pp. 395-395

Ophelia Deroy

Potential flaws in genomics paper scrutinized on Twitter pp. 397-397

Chris Woolston

Giant international trade treaties centre on science pp. 401-402

Daniel Cressey

Antibiotic alternatives rev up bacterial arms race pp. 402-403

Sara Reardon

Ebola teaches tough lessons about rapid research pp. 405-406

Erika Check Hayden

Big compromises needed to meet carbon-emissions goal pp. 405-405

Jeff Tollefson

Artificial-windpipe surgeon committed misconduct pp. 406-407

David Cyranoski

Military technology: Laser weapons get real pp. 408-410

Andy Extance

Animal behaviour: Inside the cunning, caring and greedy minds of fish pp. 412-414

Alison Abbott

Information theory: Knowledge and know-how pp. 420-421

Philip Ball

Books in brief pp. 421-421

Barbara Kiser

Laboratory history: The chemistry chronicles pp. 422-422

Derek Lowe

The mystery of the microscope in mud pp. 423-423

Brian J. Ford

Deforestation soars in the Amazon pp. 423-423

Philip Fearnside

UK bioscientists push for crop policy pp. 423-423

David Hume

Marine protection is a UK priority pp. 423-423

Calum Duncan

Robots with instincts pp. 426-427

Christoph Adami

Polarized transport in the Golgi apparatus pp. 427-428

Akihiko Nakano

The origins of a climate oscillation pp. 428-430

Sergey K. Gulev and Mojib Latif

A waste of insulin interference pp. 430-431

Erwin F. Wagner and Michele Petruzzelli

Taking the bad with the good pp. 431-432

Carl T. Bergstrom and Benjamin Kerr

The middle Pliocene gets crowded pp. 432-433

Fred Spoor

Machine intelligence pp. 435-435

Tanguy Chouard and Liesbeth Venema

Deep learning pp. 436-444

Yann LeCun, Yoshua Bengio and Geoffrey Hinton

Reinforcement learning improves behaviour from evaluative feedback pp. 445-451

Michael L. Littman

Probabilistic machine learning and artificial intelligence pp. 452-459

Zoubin Ghahramani

Science, technology and the future of small autonomous drones pp. 460-466

Dario Floreano and Robert J. Wood

Design, fabrication and control of soft robots pp. 467-475

Daniela Rus and Michael T. Tolley

From evolutionary computation to the evolution of things pp. 476-482

Agoston E. Eiben and Jim Smith

New species from Ethiopia further expands Middle Pliocene hominin diversity pp. 483-488

Yohannes Haile-Selassie, Luis Gibert, Stephanie M. Melillo, Timothy M. Ryan, Mulugeta Alene, Alan Deino, Naomi E. Levin, Gary Scott and Beverly Z. Saylor

Whole–genome characterization of chemoresistant ovarian cancer pp. 489-494

Ann-Marie Patch, Elizabeth L. Christie, Dariush Etemadmoghadam, Dale W. Garsed, Joshy George, Sian Fereday, Katia Nones, Prue Cowin, Kathryn Alsop, Peter J. Bailey, Karin S. Kassahn, Felicity Newell, Michael C. J. Quinn, Stephen Kazakoff, Kelly Quek, Charlotte Wilhelm-Benartzi, Ed Curry, Huei San Leong, Anne Hamilton, Linda Mileshkin, George Au-Yeung, Catherine Kennedy, Jillian Hung, Yoke-Eng Chiew, Paul Harnett, Michael Friedlander, Michael Quinn, Jan Pyman, Stephen Cordner, Patricia O’Brien, Jodie Leditschke, Greg Young, Kate Strachan, Paul Waring, Walid Azar, Chris Mitchell, Nadia Traficante, Joy Hendley, Heather Thorne, Mark Shackleton, David K. Miller, Gisela Mir Arnau, Richard W. Tothill, Timothy P. Holloway, Timothy Semple, Ivon Harliwong, Craig Nourse, Ehsan Nourbakhsh, Suzanne Manning, Senel Idrisoglu, Timothy J. C. Bruxner, Angelika N. Christ, Barsha Poudel, Oliver Holmes, Matthew Anderson, Conrad Leonard, Andrew Lonie, Nathan Hall, Scott Wood, Darrin F. Taylor, Qinying Xu, J. Lynn Fink, Nick Waddell, Ronny Drapkin, Euan Stronach, Hani Gabra, Robert Brown, Andrea Jewell, Shivashankar H. Nagaraj, Emma Markham, Peter J. Wilson, Jason Ellul, Orla McNally, Maria A. Doyle, Ravikiran Vedururu, Collin Stewart, Ernst Lengyel, John V. Pearson, Nicola Waddell, Anna deFazio, Sean M. Grimmond and David D. L. Bowtell

A kiloparsec-scale internal shock collision in the jet of a nearby radio galaxy pp. 495-497

Eileen T. Meyer, Markos Georganopoulos, William B. Sparks, Eric Perlman, Roeland P. van der Marel, Jay Anderson, Sangmo Tony Sohn, John Biretta, Colin Norman and Marco Chiaberge

Extreme ultraviolet high-harmonic spectroscopy of solids pp. 498-502

T. T. Luu, M. Garg, S. Yu. Kruchinin, A. Moulet, M. Th. Hassan and E. Goulielmakis

Robots that can adapt like animals pp. 503-507

Antoine Cully, Jeff Clune, Danesh Tarapore and Jean-Baptiste Mouret

Ocean impact on decadal Atlantic climate variability revealed by sea-level observations pp. 508-510

Gerard D. McCarthy, Ivan D. Haigh, Joël J.-M. Hirschi, Jeremy P. Grist and David A. Smeed

Diverse coupling of neurons to populations in sensory cortex pp. 511-515

Michael Okun, Nicholas A. Steinmetz, Lee Cossell, M. Florencia Iacaruso, Ho Ko, Péter Barthó, Tirin Moore, Sonja B. Hofer, Thomas D. Mrsic-Flogel, Matteo Carandini and Kenneth D. Harris

Counteraction of antibiotic production and degradation stabilizes microbial communities pp. 516-519

Eric D. Kelsic, Jeffrey Zhao, Kalin Vetsigian and Roy Kishony

Global genetic analysis in mice unveils central role for cilia in congenital heart disease pp. 520-524

You Li, Nikolai T. Klena, George C. Gabriel, Xiaoqin Liu, Andrew J. Kim, Kristi Lemke, Yu Chen, Bishwanath Chatterjee, William Devine, Rama Rao Damerla, Chienfu Chang, Hisato Yagi, Jovenal T. San Agustin, Mohamed Thahir, Shane Anderton, Caroline Lawhead, Anita Vescovi, Herbert Pratt, Judy Morgan, Leslie Haynes, Cynthia L. Smith, Janan T. Eppig, Laura Reinholdt, Richard Francis, Linda Leatherbury, Madhavi K. Ganapathiraju, Kimimasa Tobita, Gregory J. Pazour and Cecilia W. Lo

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans pp. 525-528

Konstantinos Palikaras, Eirini Lionaki and Nektarios Tavernarakis

Coordinated regulation of bidirectional COPI transport at the Golgi by CDC42 pp. 529-532

Seung-Yeol Park, Jia-Shu Yang, Angela B. Schmider, Roy J. Soberman and Victor W. Hsu

Defining fundamental steps in the assembly of the Drosophila RNAi enzyme complex pp. 533-536

Shintaro Iwasaki, Hiroshi M. Sasaki, Yuriko Sakaguchi, Tsutomu Suzuki, Hisashi Tadakuma and Yukihide Tomari

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection pp. 537-540

Vera Boersma, Nathalie Moatti, Sandra Segura-Bayona, Marieke H. Peuscher, Jaco van der Torre, Brigitte A. Wevers, Alexandre Orthwein, Daniel Durocher and Jacqueline J. L. Jacobs

REV7 counteracts DNA double-strand break resection and affects PARP inhibition pp. 541-544

Guotai Xu, J. Ross Chapman, Inger Brandsma, Jingsong Yuan, Martin Mistrik, Peter Bouwman, Jirina Bartkova, Ewa Gogola, Daniël Warmerdam, Marco Barazas, Janneke E. Jaspers, Kenji Watanabe, Mark Pieterse, Ariena Kersbergen, Wendy Sol, Patrick H. N. Celie, Philip C. Schouten, Bram van den Broek, Ahmed Salman, Marja Nieuwland, Iris de Rink, Jorma de Ronde, Kees Jalink, Simon J. Boulton, Junjie Chen, Dik C. van Gent, Jiri Bartek, Jos Jonkers, Piet Borst and Sven Rottenberg

Atomic structure of anthrax protective antigen pore elucidates toxin translocation pp. 545-549

Jiansen Jiang, Bradley L. Pentelute, R. John Collier and Z. Hong Zhou

Medical research: Subject to reflection pp. 551-553

Virginia Gewin

Turning point: Roberto Kolter pp. 553-553

Julie Gould

An excerpt from Dying For Dummies (2020) pp. 556-556

Norman Spinrad

2015, volume 521, articles 7552

Wild-type microglia do not reverse pathology in mouse models of Rett syndrome pp. E1-E4

Jieqi Wang, Jan Eike Wegener, Teng-Wei Huang, Smitha Sripathy, Hector De Jesus-Cortes, Pin Xu, Stephanie Tran, Whitney Knobbe, Vid Leko, Jeremiah Britt, Ruth Starwalt, Latisha McDaniel, Chris S. Ward, Diana Parra, Benjamin Newcomb, Uyen Lao, Cynthia Nourigat, David A. Flowers, Sean Cullen, Nikolas L. Jorstad, Yue Yang, Lena Glaskova, Sébastien Vigneau, Julia Kozlitina, Michael J. Yetman, Joanna L. Jankowsky, Sybille D. Reichardt, Holger M. Reichardt, Jutta Gärtner, Marisa S. Bartolomei, Min Fang, Keith Loeb, C. Dirk Keene, Irwin Bernstein, Margaret Goodell, Daniel J. Brat, Peter Huppke, Jeffrey L. Neul, Antonio Bedalov and Andrew A. Pieper

Doubtful pathways to cold tolerance in plants pp. E5-E6

Erika J. Edwards, Jurriaan M. de Vos and Michael J. Donoghue

Zanne et al. reply pp. E6-E7

Amy E. Zanne, David C. Tank, William K. Cornwell, Jonathan M. Eastman, Stephen A. Smith, Richard G. FitzJohn, Daniel J. McGlinn, Brian C. O’Meara, Angela T. Moles, Peter B. Reich, Dana L. Royer, Douglas E. Soltis, Peter F. Stevens, Mark Westoby, Ian J. Wright, Lonnie Aarssen, Robert I. Bertin, Andre Calaminus, Rafaël Govaerts, Frank Hemmings, Michelle R. Leishman, Jacek Oleksyn, Pamela S. Soltis, Nathan G. Swenson, Laura Warman and Jeremy M. Beaulieu

Bees pp. S47-S47

Michelle Grayson

Meet our prime pollinators pp. S48-S49

Julie Gould

The beeline pp. S50-S51

Sarah DeWeerdt

Pesticides: Seeking answers amid a toxic debate pp. S52-S55

Michael Eisenstein

Microbiome: The puzzle in a bee's gut pp. S56-S56

Alla Katsnelson

Animal behaviour: Nested instincts pp. S60-S61

Lauren Gravitz

Wild bees: Lone rangers pp. S62-S63

Lucas Laursen

Aerodynamics: Vortices and robobees pp. S64-S65

Neil Savage

Q&A: Charles Michener pp. S66-S66

Julie Gould

No more hidden solutions in bioinformatics pp. 261-261

Mauno Vihinen

Fruit-fly paper has 1,000 authors pp. 263-263

Chris Woolston

Engineered yeast paves way for home-brew heroin pp. 267-268

Rachel Ehrenberg

Aid burst lifts people out of extreme poverty pp. 269-269

Declan Butler

Congress seeks to quash patent trolls pp. 270-271

Heidi Ledford

UK universities slow to publish reports of misconduct investigations pp. 271-271

Elizabeth Gibney

Billion-dollar particle collider gets thumbs up pp. 272-272

Edwin Cartlidge

Russia turns screw on science foundation pp. 273-273

Quirin Schiermeier

Reproducibility crisis: Blame it on the antibodies pp. 274-276

Monya Baker

Quantum physics: What is really real? pp. 278-280

Zeeya Merali

Drugs: Regulate 'home-brew' opiates pp. 281-283

Kenneth A. Oye, J. Chappell H. Lawson and Tania Bubela

Sustainability: Clean cooking empowers women pp. 284-285

Laura S. Brown and William F. Lankford

Physics: Fighting for time pp. 286-287

Graham Farmelo

Books in brief pp. 287-287

Barbara Kiser

Palaeontology: Tracing the backbone in China's rocks pp. 288-288

Xu Xing

Engage public in gene-editing policy pp. 289-289

Filippa Lentzos

Blood-transfusion decisions not simple pp. 289-289

Harvey G. Klein, Irene Cortés-Puch and Charles Natanson

Water: Megacities running dry in Brazil pp. 289-289

Richard Meganck, Karl Havens and Ricardo M. Pinto-Coelho

Water: Halt India's groundwater loss pp. 289-289

Bobban Subhadra

Water: A drought plan for biodiversity pp. 289-289

Alexander C. Lees and Peter Bowler

Alexander Rich (1924–2015) pp. 291-291

Paul Schimmel

Tools go back in time pp. 294-295

Erella Hovers

Squeezed ions in two places at once pp. 295-296

Tracy Northup

Asymmetric rejuvenation pp. 296-298

Anu Suomalainen

Magnetic alloys break the rules pp. 298-299

Richard D. James

Equilibrium established pp. 299-300

Kyle M. Loh and Bing Lim

Splicing does the two-step pp. 301-301

Heidi Cook-Andersen and Miles F. Wilkinson

The crystallography of correlated disorder pp. 303-309

David A. Keen and Andrew L. Goodwin

3.3-million-year-old stone tools from Lomekwi 3, West Turkana, Kenya pp. 310-315

Sonia Harmand, Jason E. Lewis, Craig S. Feibel, Christopher J. Lepre, Sandrine Prat, Arnaud Lenoble, Xavier Boës, Rhonda L. Quinn, Michel Brenet, Adrian Arroyo, Nicholas Taylor, Sophie Clément, Guillaume Daver, Jean-Philip Brugal, Louise Leakey, Richard A. Mortlock, James D. Wright, Sammy Lokorodi, Christopher Kirwa, Dennis V. Kent and Hélène Roche

An alternative pluripotent state confers interspecies chimaeric competency pp. 316-321

Jun Wu, Daiji Okamura, Mo Li, Keiichiro Suzuki, Chongyuan Luo, Li Ma, Yupeng He, Zhongwei Li, Chris Benner, Isao Tamura, Marie N. Krause, Joseph R. Nery, Tingting Du, Zhuzhu Zhang, Tomoaki Hishida, Yuta Takahashi, Emi Aizawa, Na Young Kim, Jeronimo Lajara, Pedro Guillen, Josep M. Campistol, Concepcion Rodriguez Esteban, Pablo J. Ross, Alan Saghatelian, Bing Ren, Joseph R. Ecker and Juan Carlos Izpisua Belmonte

Neurotransmitter and psychostimulant recognition by the dopamine transporter pp. 322-327

Kevin H. Wang, Aravind Penmatsa and Eric Gouaux

A strong ultraviolet pulse from a newborn type Ia supernova pp. 328-331

Yi Cao, S. R. Kulkarni, D. Andrew Howell, Avishay Gal-Yam, Mansi M. Kasliwal, Stefano Valenti, J. Johansson, R. Amanullah, A. Goobar, J. Sollerman, F. Taddia, Assaf Horesh, Ilan Sagiv, S. Bradley Cenko, Peter E. Nugent, Iair Arcavi, Jason Surace, P. R. Woźniak, Daniela I. Moody, Umaa D. Rebbapragada, Brian D. Bue and Neil Gehrels

No signature of ejecta interaction with a stellar companion in three type Ia supernovae pp. 332-335

Rob P. Olling, Richard Mushotzky, Edward J. Shaya, Armin Rest, Peter M. Garnavich, Brad E. Tucker, Daniel Kasen, Steve Margheim and Alexei V. Filippenko

Spin–motion entanglement and state diagnosis with squeezed oscillator wavepackets pp. 336-339

Hsiang-Yu Lo, Daniel Kienzler, Ludwig de Clercq, Matteo Marinelli, Vlad Negnevitsky, Ben C. Keitch and Jonathan P. Home

Non-Joulian magnetostriction pp. 340-343

Harsh Deep Chopra and Manfred Wuttig

Selection on noise constrains variation in a eukaryotic promoter pp. 344-347

Brian P. H. Metzger, David C. Yuan, Jonathan D. Gruber, Fabien Duveau and Patricia J. Wittkopp

Selective corticostriatal plasticity during acquisition of an auditory discrimination task pp. 348-351

Qiaojie Xiong, Petr Znamenskiy and Anthony M. Zador

Early reprogramming regulators identified by prospective isolation and mass cytometry pp. 352-356

Ernesto Lujan, Eli R. Zunder, Yi Han Ng, Isabel N. Goronzy, Garry P. Nolan and Marius Wernig

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia pp. 357-361

Zhengshan Chen, Seyedmehdi Shojaee, Maike Buchner, Huimin Geng, Jae Woong Lee, Lars Klemm, Björn Titz, Thomas G. Graeber, Eugene Park, Ying Xim Tan, Anne Satterthwaite, Elisabeth Paietta, Stephen P. Hunger, Cheryl L. Willman, Ari Melnick, Mignon L. Loh, Jae U. Jung, John E. Coligan, Silvia Bolland, Tak W. Mak, Andre Limnander, Hassan Jumaa, Michael Reth, Arthur Weiss, Clifford A. Lowell and Markus Müschen

Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates pp. 362-365

Emily P. Thi, Chad E. Mire, Amy C. H. Lee, Joan B. Geisbert, Joy Z. Zhou, Krystle N. Agans, Nicholas M. Snead, Daniel J. Deer, Trisha R. Barnard, Karla A. Fenton, Ian MacLachlan and Thomas W. Geisbert

Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice pp. 366-370

Rene C. Adam, Hanseul Yang, Shira Rockowitz, Samantha B. Larsen, Maria Nikolova, Daniel S. Oristian, Lisa Polak, Meelis Kadaja, Amma Asare, Deyou Zheng and Elaine Fuchs

Recursive splicing in long vertebrate genes pp. 371-375

Christopher R. Sibley, Warren Emmett, Lorea Blazquez, Ana Faro, Nejc Haberman, Michael Briese, Daniah Trabzuni, Mina Ryten, Michael E. Weale, John Hardy, Miha Modic, Tomaž Curk, Stephen W. Wilson, Vincent Plagnol and Jernej Ule

Genome-wide identification of zero nucleotide recursive splicing in Drosophila pp. 376-379

Michael O. Duff, Sara Olson, Xintao Wei, Sandra C. Garrett, Ahmad Osman, Mohan Bolisetty, Alex Plocik, Susan E. Celniker and Brenton R. Graveley

Correction: Corrigendum: Three keys to the radiation of angiosperms into freezing environments pp. 380-380

Amy E. Zanne, David C. Tank, William K. Cornwell, Jonathan M. Eastman, Stephen A. Smith, Richard G. FitzJohn, Daniel J. McGlinn, Brian C. O'Meara, Angela T. Moles, Peter B. Reich, Dana L. Royer, Douglas E. Soltis, Peter F. Stevens, Mark Westoby, Ian J. Wright, Lonnie Aarssen, Robert I. Bertin, Andre Calaminus, Rafaël Govaerts, Frank Hemmings, Michelle R. Leishman, Jacek Oleksyn, Pamela S. Soltis, Nathan G. Swenson, Laura Warman and Jeremy M. Beaulieu

Correction: Corrigendum: Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1 pp. 380-380

Jaime N. Guzman, Javier Sanchez-Padilla, David Wokosin, Jyothisri Kondapalli, Ema Ilijic, Paul T. Schumacker and D. James Surmeier

Relocation: Out of place pp. 381-383

Paul Smaglik

Turning point: Josh Dillon pp. 383-383

Virginia Gewin

Grains of wheat pp. 386-386

Alex Shvartsman

2015, volume 521, articles 7551

Colorectal cancer pp. S1-S1

Herb Brody

A disease of growth pp. S2-S3

David Holmes

Screening: Early alert pp. S4-S5

Cassandra Willyard

Prevention: Tending the gut pp. S6-S8

Lauren Gravitz

Q&A: Victor Velculescu pp. S9-S9

Eric Bender

Microbiome: Microbial mystery pp. S10-S11

Sarah DeWeerdt

Drug development: Mix and match pp. S12-S14

Megan Scudellari

Q&A: Hans Clevers pp. S15-S15

Eric Bender

Colorectal cancer: 5 big questions pp. S16-S16

Shraddha Chakradhar

Regulate gene editing in wild animals pp. 127-127

Jeantine Lunshof

Microwave oven blamed for radio-telescope signals pp. 129-129

Chris Woolston

Mappers rush to pinpoint landslide risk in Nepal pp. 133-134

Alexandra Witze

What the UK election results mean for science pp. 134-134

Elizabeth Gibney

Rogue antimatter found in thunderclouds pp. 135-135

Davide Castelvecchi

Microbiomes raise privacy concerns pp. 136-136

Ewen Callaway

Ebola failures prompt WHO rethink pp. 137-137

Erika Check Hayden

India eases stance on GM crop trials pp. 138-139

Sanjay Kumar

India by the numbers pp. 142-143

Richard Van Noorden

India: The fight to become a science superpower pp. 144-147

T. V. Padma

Indian bioscience: The anti-bureaucrat pp. 148-150

Apoorva Mandavilli

Policy: Rethink India's energy strategy pp. 156-157

Arunabha Ghosh and Karthik Ganesan

Autobiography: In search of self and science pp. 158-159

Tim Radford

Science fiction: After the cataclysm pp. 159-159

John Gilbey

Neurophysiology: The man who bared the brain pp. 160-160

Alison Abbott

IPCC: social scientists are ready pp. 161-161

Paul C. Stern and Thomas Dietz

IPCC: calling social scientists of all kinds pp. 161-161

Mathieu Denis and Susanne C. Moser

Plant identification is key to conservation pp. 161-161

Anna Trias-Blasi and Maria Vorontsova

Citizen science is not enough on its own pp. 161-161

Rod Kennett, Finn Danielsen and Kirsten M. Silvius

Check the rejects for fame bias too pp. 161-161

Davide Nespoli

The slow death of red galaxies pp. 164-165

Andrea Cattaneo

Internal compass puts flies in their place pp. 165-166

Thomas R. Clandinin and Lisa M. Giocomo

Quantum control of free electrons pp. 166-167

Mathieu Kociak

Fungus against the wall pp. 168-169

Paul O'Maille

Steps on the road to eukaryotes pp. 169-170

T. Martin Embley and Tom A. Williams

Rap and chirp about X inactivation pp. 170-171

Anna Roth and Sven Diederichs

Complex archaea that bridge the gap between prokaryotes and eukaryotes pp. 173-179

Anja Spang, Jimmy H. Saw, Steffen L. Jørgensen, Katarzyna Zaremba-Niedzwiedzka, Joran Martijn, Anders E. Lind, Roel van Eijk, Christa Schleper, Lionel Guy and Thijs J. G. Ettema

Neurons for hunger and thirst transmit a negative-valence teaching signal pp. 180-185

J. Nicholas Betley, Shengjin Xu, Zhen Fang Huang Cao, Rong Gong, Christopher J. Magnus, Yang Yu and Scott M. Sternson

Neural dynamics for landmark orientation and angular path integration pp. 186-191

Johannes D. Seelig and Vivek Jayaraman

Strangulation as the primary mechanism for shutting down star formation in galaxies pp. 192-195

Y. Peng, R. Maiolino and R. Cochrane

Electron pairing without superconductivity pp. 196-199

Guanglei Cheng, Michelle Tomczyk, Shicheng Lu, Joshua P. Veazey, Mengchen Huang, Patrick Irvin, Sangwoo Ryu, Hyungwoo Lee, Chang-Beom Eom, C. Stephen Hellberg and Jeremy Levy

Quantum coherent optical phase modulation in an ultrafast transmission electron microscope pp. 200-203

Armin Feist, Katharina E. Echternkamp, Jakob Schauss, Sergey V. Yalunin, Sascha Schäfer and Claus Ropers

Global carbon export from the terrestrial biosphere controlled by erosion pp. 204-207

Valier Galy, Bernhard Peucker-Ehrenbrink and Timothy Eglinton

Multi-omics of permafrost, active layer and thermokarst bog soil microbiomes pp. 208-212

Jenni Hultman, Mark P. Waldrop, Rachel Mackelprang, Maude M. David, Jack McFarland, Steven J. Blazewicz, Jennifer Harden, Merritt R. Turetsky, A. David McGuire, Manesh B. Shah, Nathan C. VerBerkmoes, Lang Ho Lee, Kostas Mavrommatis and Janet K. Jansson

Pathogen-secreted proteases activate a novel plant immune pathway pp. 213-216

Zhenyu Cheng, Jian-Feng Li, Yajie Niu, Xue-Cheng Zhang, Owen Z. Woody, Yan Xiong, Slavica Djonović, Yves Millet, Jenifer Bush, Brendan J. McConkey, Jen Sheen and Frederick M. Ausubel

YAP is essential for tissue tension to ensure vertebrate 3D body shape pp. 217-221

Sean Porazinski, Huijia Wang, Yoichi Asaoka, Martin Behrndt, Tatsuo Miyamoto, Hitoshi Morita, Shoji Hata, Takashi Sasaki, S. F. Gabriel Krens, Yumi Osada, Satoshi Asaka, Akihiro Momoi, Sarah Linton, Joel B. Miesfeld, Brian A. Link, Takeshi Senga, Atahualpa Castillo-Morales, Araxi O. Urrutia, Nobuyoshi Shimizu, Hideaki Nagase, Shinya Matsuura, Stefan Bagby, Hisato Kondoh, Hiroshi Nishina, Carl-Philipp Heisenberg and Makoto Furutani-Seiki

Clinical improvement in psoriasis with specific targeting of interleukin-23 pp. 222-226

Tamara Kopp, Elisabeth Riedl, Christine Bangert, Edward P. Bowman, Elli Greisenegger, Ann Horowitz, Harald Kittler, Wendy M. Blumenschein, Terrill K. McClanahan, Thomas Marbury, Claus Zachariae, Danlin Xu, Xiaoli Shirley Hou, Anish Mehta, Anthe S. Zandvliet, Diana Montgomery, Frank van Aarle and Sauzanne Khalilieh

Nuclear architecture dictates HIV-1 integration site selection pp. 227-231

Bruna Marini, Attila Kertesz-Farkas, Hashim Ali, Bojana Lucic, Kamil Lisek, Lara Manganaro, Sandor Pongor, Roberto Luzzati, Alessandra Recchia, Fulvio Mavilio, Mauro Giacca and Marina Lusic

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3 pp. 232-236

Colleen A. McHugh, Chun-Kan Chen, Amy Chow, Christine F. Surka, Christina Tran, Patrick McDonel, Amy Pandya-Jones, Mario Blanco, Christina Burghard, Annie Moradian, Michael J. Sweredoski, Alexander A. Shishkin, Julia Su, Eric S. Lander, Sonja Hess, Kathrin Plath and Mitchell Guttman

Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase pp. 237-240

Matteo Allegretti, Niklas Klusch, Deryck J. Mills, Janet Vonck, Werner Kühlbrandt and Karen M. Davies

Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase pp. 241-245

Jianhua Zhao, Samir Benlekbir and John L. Rubinstein

Erratum: Entanglement with negative Wigner function of almost 3,000 atoms heralded by one photon pp. 246-246

Robert McConnell, Hao Zhang, Jiazhong Hu, Senka Ćuk and Vladan Vuletić

Adjunct teaching: For love of the lecture pp. 247-249

Kendall Powell

When last I saw the stars pp. 252-252

Jeff Hecht

2015, volume 521, articles 7550

Keep the directive that protects research animals pp. 7-7

Kay Davies

Sexist review causes Twitter storm pp. 9-9

Chris Woolston

Japanese academics spooked by military science incursions pp. 13-14

David Cyranoski

Pluto-bound craft hunts for hazardous moons pp. 14-15

Alexandra Witze

Pint-sized DNA sequencer impresses first users pp. 15-16

Erika Check Hayden

Fossil-fuel divestment campaign hits resistance pp. 16-17

Jeff Tollefson

Mysterious galactic signal points LHC to dark matter pp. 17-18

Davide Castelvecchi

Mammoth genomes provide recipe for creating Arctic elephants pp. 18-19

Ewen Callaway

The retirement debate: Stay at the bench, or make way for the next generation pp. 20-23

Megan Scudellari

Research: Africa's fight for equality pp. 24-25

Linda Nordling

Policy: Climate advisers must maintain integrity pp. 27-28

Oliver Geden

Apiculture: Telling the bees pp. 29-30

John Burnside

De-extinction: A behemoth revived pp. 30-31

Henry Nicholls

Books in brief pp. 31-31

Barbara Kiser

Forests: See the trees and the wood pp. 32-32

Hans Henrik Bruun, Jacob Heilmann-Clausen and Rasmus Ejrnæs

Forests: Not just timber plantations pp. 32-32

Bengt Gunnar Jonsson, Guy Pe'er and Miroslav Svoboda

Research network to track alpine water pp. 32-32

John Pomeroy, Matthias Bernhardt and Daniel Marks

Botanists still need to tell plants apart pp. 32-32

Martin Kemler

Interim initiative for health in Iran pp. 32-32

Ali Akbar Velayati, Hamidreza Jamaati and Seyed Mohammadreza Hashemian

Beauty varies with the light pp. 34-35

Ole Seehausen

Antibodies regulate antitumour immunity pp. 35-37

Laurence Zitvogel and Guido Kroemer

Nanoscale connections for brain-like circuits pp. 37-38

Robert Legenstein

Tasteless pesticides affect bees in the field pp. 38-39

Nigel E. Raine and Richard J. Gill

Dinosaur up in the air pp. 40-41

Kevin Padian

Organic polymers form fuel from water pp. 41-42

Vijay S. Vyas and Bettina V. Lotsch

Sequential cancer mutations in cultured human intestinal stem cells pp. 43-47

Jarno Drost, Richard H. van Jaarsveld, Bas Ponsioen, Cheryl Zimberlin, Ruben van Boxtel, Arjan Buijs, Norman Sachs, René M. Overmeer, G. Johan Offerhaus, Harry Begthel, Jeroen Korving, Marc van de Wetering, Gerald Schwank, Meike Logtenberg, Edwin Cuppen, Hugo J. Snippert, Jan Paul Medema, Geert J. P. L. Kops and Hans Clevers

Structural basis for Na+ transport mechanism by a light-driven Na+ pump pp. 48-53

Hideaki E. Kato, Keiichi Inoue, Rei Abe-Yoshizumi, Yoshitaka Kato, Hikaru Ono, Masae Konno, Shoko Hososhima, Toru Ishizuka, Mohammad Razuanul Hoque, Hirofumi Kunitomo, Jumpei Ito, Susumu Yoshizawa, Keitaro Yamashita, Mizuki Takemoto, Tomohiro Nishizawa, Reiya Taniguchi, Kazuhiro Kogure, Andrés D. Maturana, Yuichi Iino, Hiromu Yawo, Ryuichiro Ishitani, Hideki Kandori and Osamu Nureki

An extremely young massive clump forming by gravitational collapse in a primordial galaxy pp. 54-56

A. Zanella, E. Daddi, E. Le Floc’h, F. Bournaud, R. Gobat, F. Valentino, V. Strazzullo, A. Cibinel, M. Onodera, V. Perret, F. Renaud and C. Vignali

Curtain eruptions from Enceladus’ south-polar terrain pp. 57-60

Joseph N. Spitale, Terry A. Hurford, Alyssa R. Rhoden, Emily E. Berkson and Symeon S. Platts

Training and operation of an integrated neuromorphic network based on metal-oxide memristors pp. 61-64

M. Prezioso, F. Merrikh-Bayat, B. D. Hoskins, G. C. Adam, K. K. Likharev and D. B. Strukov

The formation and fate of internal waves in the South China Sea pp. 65-69

Matthew H. Alford, Thomas Peacock, Jennifer A. MacKinnon, Jonathan D. Nash, Maarten C. Buijsman, Luca R. Centurioni, Shenn-Yu Chao, Ming-Huei Chang, David M. Farmer, Oliver B. Fringer, Ke-Hsien Fu, Patrick C. Gallacher, Hans C. Graber, Karl R. Helfrich, Steven M. Jachec, Christopher R. Jackson, Jody M. Klymak, Dong S. Ko, Sen Jan, T. M. Shaun Johnston, Sonya Legg, I-Huan Lee, Ren-Chieh Lien, Matthieu J. Mercier, James N. Moum, Ruth Musgrave, Jae-Hun Park, Andrew I. Pickering, Robert Pinkel, Luc Rainville, Steven R. Ramp, Daniel L. Rudnick, Sutanu Sarkar, Alberto Scotti, Harper L. Simmons, Louis C. St Laurent, Subhas K. Venayagamoorthy, Yu-Huai Wang, Joe Wang, Yiing J. Yang, Theresa Paluszkiewicz and Tswen-Yung (David) Tang

A bizarre Jurassic maniraptoran theropod with preserved evidence of membranous wings pp. 70-73

Xing Xu, Xiaoting Zheng, Corwin Sullivan, Xiaoli Wang, Lida Xing, Yan Wang, Xiaomei Zhang, Jingmai K. O’Connor, Fucheng Zhang and Yanhong Pan

Bees prefer foods containing neonicotinoid pesticides pp. 74-76

Sébastien C. Kessler, Erin Jo Tiedeken, Kerry L. Simcock, Sophie Derveau, Jessica Mitchell, Samantha Softley, Amy Radcliffe, Jane C. Stout and Geraldine A. Wright

Seed coating with a neonicotinoid insecticide negatively affects wild bees pp. 77-80

Maj Rundlöf, Georg K. S. Andersson, Riccardo Bommarco, Ingemar Fries, Veronica Hederström, Lina Herbertsson, Ove Jonsson, Björn K. Klatt, Thorsten R. Pedersen, Johanna Yourstone and Henrik G. Smith

Differential DNA mismatch repair underlies mutation rate variation across the human genome pp. 81-84

Fran Supek and Ben Lehner

A direct GABAergic output from the basal ganglia to frontal cortex pp. 85-89

Arpiar Saunders, Ian A. Oldenburg, Vladimir K. Berezovskii, Caroline A. Johnson, Nathan D. Kingery, Hunter L. Elliott, Tiao Xie, Charles R. Gerfen and Bernardo L. Sabatini

Vertically transmitted faecal IgA levels determine extra-chromosomal phenotypic variation pp. 90-93

Clara Moon, Megan T. Baldridge, Meghan A. Wallace, Carey-Ann D. Burnham, Herbert W. Virgin and Thaddeus S. Stappenbeck

Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy pp. 94-98

Shabnam Shalapour, Joan Font-Burgada, Giuseppe Di Caro, Zhenyu Zhong, Elsa Sanchez-Lopez, Debanjan Dhar, Gerald Willimsky, Massimo Ammirante, Amy Strasner, Donna E. Hansel, Christina Jamieson, Christopher J. Kane, Tobias Klatte, Peter Birner, Lukas Kenner and Michael Karin

Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity pp. 99-104

Yaron Carmi, Matthew H. Spitzer, Ian L. Linde, Bryan M. Burt, Tyler R. Prestwood, Nicola Perlman, Matthew G. Davidson, Justin A. Kenkel, Ehud Segal, Ganesh V. Pusapati, Nupur Bhattacharya and Edgar G. Engleman

X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis pp. 105-109

Kristina Haslinger, Madeleine Peschke, Clara Brieke, Egle Maximowitsch and Max J. Cryle

Retraction Note: Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1 pp. 110-110

Christian Beisel, Axel Imhof, Jaime Greene, Elisabeth Kremmer and Frank Sauer

The trouble with reference rot pp. 111-112

Jeffrey M. Perkel

'Living figures' make their debut pp. 112-112

Dalmeet Singh Chawla

Recognition: Build a reputation pp. 113-115

Chris Woolston

Visual maps bring research to life pp. 115-115

Åsmund Eikenes

Tempus omnia revelat pp. 118-118

Tian Li