Inside-out receptor inhibition

Thomas P. Sakmar () and Thomas Huber ()
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Thomas P. Sakmar: Thomas P. Sakmar and Thomas Huber are in the Laboratory of Chemical Biology and Signal Transduction, The Rockefeller University, New York, New York 10065, USA.
Thomas Huber: Thomas P. Sakmar and Thomas Huber are in the Laboratory of Chemical Biology and Signal Transduction, The Rockefeller University, New York, New York 10065, USA.

Nature, 2016, vol. 540, issue 7633, 344-345

Abstract: Structures of two chemokine receptor proteins in complex with small molecules reveal a previously unknown binding pocket that could be a drug target for treating a range of diseases involving this receptor family. See Letters p.458 & p.462

Date: 2016
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DOI: 10.1038/nature20486

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