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High-resolution crystal structure of the human CB1 cannabinoid receptor

Zhenhua Shao, Jie Yin, Karen Chapman, Magdalena Grzemska, Lindsay Clark, Junmei Wang and Daniel M. Rosenbaum ()
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Zhenhua Shao: The University of Texas Southwestern Medical Center
Jie Yin: The University of Texas Southwestern Medical Center
Karen Chapman: The University of Texas Southwestern Medical Center
Magdalena Grzemska: The University of Texas Southwestern Medical Center
Lindsay Clark: The University of Texas Southwestern Medical Center
Junmei Wang: Green Center for Systems Biology, The University of Texas Southwestern Medical Center
Daniel M. Rosenbaum: The University of Texas Southwestern Medical Center

Nature, 2016, vol. 540, issue 7634, 602-606

Abstract: The authors report a 2.6 Å resolution crystal structure of the human CB1 cannabinoid receptor trapped in the inactive conformation and bound to the antagonist taranabant.

Date: 2016
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DOI: 10.1038/nature20613

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