Zika virus infection damages the testes in mice

Jennifer Govero, Prabagaran Esakky, Suzanne M. Scheaffer, Estefania Fernandez, Andrea Drury, Derek J. Platt, Matthew J. Gorman, Justin M. Richner, Elizabeth A. Caine, Vanessa Salazar, Kelle H. Moley () and Michael S. Diamond ()
Additional contact information
Jennifer Govero: Washington University School of Medicine
Prabagaran Esakky: Washington University School of Medicine
Suzanne M. Scheaffer: Washington University School of Medicine
Estefania Fernandez: Washington University School of Medicine
Andrea Drury: Washington University School of Medicine
Derek J. Platt: Washington University School of Medicine
Matthew J. Gorman: Washington University School of Medicine
Justin M. Richner: Washington University School of Medicine
Elizabeth A. Caine: Washington University School of Medicine
Vanessa Salazar: Washington University School of Medicine
Kelle H. Moley: Washington University School of Medicine
Michael S. Diamond: Washington University School of Medicine

Nature, 2016, vol. 540, issue 7633, 438-442

Abstract: Infection of male mice with Zika virus caused testicular and epididymal damage, reduction in sex hormone levels, destruction of germ and somatic cells in the testis, loss of mature sperm and reduction in fertility.

Date: 2016
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DOI: 10.1038/nature20556

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