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2002, volume 418, articles 6901

Inspiration and opportunity pp. 3-3

Paul Smaglik

Central Europe braced for tide of pollution in flood aftermath pp. 905-905

Quirin Schiermeier

Web extends to bottom of the world pp. 905-905

David Adam

US prepares ground for security clampdown pp. 906-906

Erika Check

Oceanographer navigates path to the Smithsonian pp. 906-906

Kendall Powell

Fraud inquiry leaves online paper in the ether pp. 907-907

Geoff Brumfiel

Pike pests ravage Alaska's salmon pp. 907-907

Rex Dalton

French agency plans biomedical reformation pp. 908-908

Sally Goodman

Hologram technique to flush out features of bog body pp. 908-908

Alison Abbott

Almost human pp. 910-912

David Cyranoski

Fire from ice pp. 913-914

David Adam

Vaccines should be kept even if polio is wiped out pp. 915-915

Jeronimo Cello, Aniko V. Paul and Eckard Wimmer

Arp2/3 plays no role in muscle contraction pp. 915-915

Thomas D. Pollard, Dorit Hanein and Niels Volkmann

Seeing stars pp. 915-915

Rob A. Gruters

Thriving UCSF needs all the space it can get pp. 915-915

Regis Kelly

Efforts to revive Serbian science pp. 915-915

Petar Grujic

Shadows of Plato's genes pp. 917-918

Rudolf A. Raff

Trying to make sense of art pp. 918-919

Semir Zeki

A rounded view of Faraday pp. 919-919

Jacqueline Reynolds and Charles Tanford

The temperature of everything pp. 919-920

Vaclav Smil

Science in culture pp. 920-920

Liz Hoggard

Ageing: A lethal side-effect pp. 921-921

Linda Partridge and David Gems

Inside the professionals pp. 923-924

Jonathan W. Yewdell and David C. Tscharke

Birth of a Solar System pp. 924-925

A. G. W. Cameron

Unveiling an ocean phantom pp. 925-926

Vera L. Trainer

Sculpture of a fly's head pp. 926-927

Jun R. Huh and Bruce A. Hay

Crossing the highway pp. 928-928

Heike Langenberg

Harnessing hydrogen pp. 928-929

Esteban Chornet and Stefan Czernik

The molecules of forgetfulness pp. 929-930

Alcino J. Silva and Sheena A. Josselyn

Widespread local house-sparrow extinctions pp. 931-932

David G. Hole, Mark J. Whittingham, Richard B. Bradbury, Guy Q. A. Anderson, Patricia L. M. Lee, Jeremy D. Wilson and John R. Krebs

Cognitive change and the APOE ɛ4 allele pp. 932-932

Ian J. Deary, Martha C. Whiteman, Alison Pattie, John M. Starr, Caroline Hayward, Alan F. Wright, Andrew Carothers and Lawrence J. Whalley

Fast heating scalable to laser fusion ignition pp. 933-934

R. Kodama, H. Shiraga, K. Shigemori, Y. Toyama, S. Fujioka, H. Azechi, H. Fujita, H. Habara, T. Hall, Y. Izawa, T. Jitsuno, Y. Kitagawa, K. M. Krushelnick, K. L. Lancaster, K. Mima, K. Nagai, M. Nakai, H. Nishimura, T. Norimatsu, P. A. Norreys, S. Sakabe, K. A. Tanaka, A. Youssef, M. Zepf and T. Yamanaka

RAF/RAS oncogenes and mismatch-repair status pp. 934-934

Harith Rajagopalan, Alberto Bardelli, Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein and Victor E. Velculescu

Coordination of circadian timing in mammals pp. 935-941

Steven M. Reppert and David R. Weaver

Open channel structure of MscL and the gating mechanism of mechanosensitive channels pp. 942-948

Eduardo Perozo, D. Marien Cortes, Pornthep Sompornpisut, Anna Kloda and Boris Martinac

A short timescale for terrestrial planet formation from Hf–W chronometry of meteorites pp. 949-952

Qingzhu Yin, S. B. Jacobsen, K. Yamashita, J. Blichert-Toft, P. Télouk and F. Albarède

Rapid accretion and early core formation on asteroids and the terrestrial planets from Hf–W chronometry pp. 952-955

T. Kleine, C. Münker, K. Mezger and H. Palme

Metal–insulator transition in chains with correlated disorder pp. 955-959

Pedro Carpena, Pedro Bernaola-Galván, Plamen Ch. Ivanov and H. Eugene Stanley

Near-infrared sensitivity enhancement of photorefractive polymer composites by pre-illumination pp. 959-964

Erwin Mecher, Francisco Gallego-Gómez, Hartwig Tillmann, Hans-Heinrich Hörhold, Jan C. Hummelen and Klaus Meerholz

Hydrogen from catalytic reforming of biomass-derived hydrocarbons in liquid water pp. 964-967

R. D. Cortright, R. R. Davda and J. A. Dumesic

Pfiesteria shumwayae kills fish by micropredation not exotoxin secretion pp. 967-970

Wolfgang K. Vogelbein, Vincent J. Lovko, Jeffrey D. Shields, Kimberly S. Reece, Patrice L. Mason, Leonard W. Haas and Calvin C. Walker

Protein phosphatase 1 is a molecular constraint on learning and memory pp. 970-975

David Genoux, Ursula Haditsch, Marlen Knobloch, Aubin Michalon, Daniel Storm and Isabelle M. Mansuy

Chromosomal clustering of muscle-expressed genes in Caenorhabditis elegans pp. 975-979

Peter J. Roy, Joshua M. Stuart, Jim Lund and Stuart K. Kim

Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity pp. 979-983

Ying Litingtung, Randall D. Dahn, Yina Li, John F. Fallon and Chin Chiang

T-cell engagement of dendritic cells rapidly rearranges MHC class II transport pp. 983-988

Marianne Boes, Jan Cerny, Ramiro Massol, Marjolein Op den Brouw, Tom Kirchhausen, Jianzhu Chen and Hidde L. Ploegh

Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane pp. 988-994

Amy Chow, Derek Toomre, Wendy Garrett and Ira Mellman

A chromatin remodelling complex that loads cohesin onto human chromosomes pp. 994-998

Mohamed-Ali Hakimi, Daniel A. Bochar, John A. Schmiesing, Yuanshu Dong, Orr G. Barak, David W. Speicher, Kyoko Yokomori and Ramin Shiekhattar

Reverse engineering of the giant muscle protein titin pp. 998-1002

Hongbin Li, Wolfgang A. Linke, Andres F. Oberhauser, Mariano Carrion-Vazquez, Jason G. Kerkvliet, Hui Lu, Piotr E. Marszalek and Julio M. Fernandez

2002, volume 418, articles 6900

In search of the truth pp. 3-3

Paul Smaglik

Environmental impact tops list of fears about transgenic animals pp. 805-805

Erika Check

Public-access group plans journals pp. 805-805

Kendall Powell

Comet mission collapses as craft disappears pp. 806-806

Tony Reichhardt

Nobel laureate's dream for brain research finds home pp. 806-806

Alison Abbott

Census of marine migration launched to gauge fish stocks pp. 807-807

Rex Dalton

Controversial animal feed builds concrete career in construction pp. 807-807

David Adam

Anthrax case provokes doubt among experts pp. 808-808

Jonathan Knight and Erika Check

Wanted: scientists for sustainability pp. 812-814

Tom Clarke

A very brief encounter pp. 815-816

Kendall Powell

Summit: vague answers to well-known problems? pp. 817-817

Evan D. G. Fraser and Warren Mabee

Physicists take issue of misconduct seriously pp. 817-817

William F. Brinkman

Fraud: the system works pp. 817-817

Ivan K. Schuller and Gernot Guentherodt

Impartial review is key pp. 817-817

George Crabtree

The price of consumerism pp. 819-820

Norman Myers

The quest for the Jesuit's bark pp. 820-821

Sandra Knapp

A modern kind of magic pp. 821-821

Alan Stewart

Metastasis genes: A progression puzzle pp. 823-823

René Bernards and Robert A. Weinberg

Virus deals anthrax a killer blow pp. 825-826

M. J. Rosovitz and Stephen H. Leppla

Lasing on a cloudy afternoon pp. 826-827

Stephan Borrmann and Joachim Curtius

Mitochondria in hiding pp. 827-829

Andrew J. Roger and Jeffrey D. Silberman

Inside whitecaps pp. 830-830

Mark Loewen

Tuning in by turning off pp. 831-833

Ron Hoy

Smog report pp. 833-834

Robert E. Samuelson

Openness in management pp. 834-835

William J. Sutherland

A block at the toll gate pp. 835-836

Tak W. Mak and Wen-Chen Yeh

Rapid renewal of auditory hair bundles pp. 837-838

Mark E. Schneider, Inna A. Belyantseva, Ricardo B. Azevedo and Bechara Kachar

Fast hands-free writing by gaze direction pp. 838-838

David J. Ward and David J. C. MacKay

Scale dependence of bubble creation mechanisms in breaking waves pp. 839-844

Grant B. Deane and M. Dale Stokes

Directionally selective calcium signals in dendrites of starburst amacrine cells pp. 845-852

Thomas Euler, Peter B. Detwiler and Winfried Denk

A wind origin for Titan's haze structure pp. 853-856

P. Rannou, F. Hourdin and C. P. McKay

Emergent excitations in a geometrically frustrated magnet pp. 856-858

S.-H. Lee, C. Broholm, W. Ratcliff, G. Gasparovic, Q. Huang, T. H. Kim and S.-W. Cheong

Chemical investigation of hassium (element 108) pp. 859-862

Ch. E. Düllmann, W. Brüchle, R. Dressler, K. Eberhardt, B. Eichler, R. Eichler, H. W. Gäggeler, T. N. Ginter, F. Glaus, K. E. Gregorich, D. C. Hoffman, E. Jäger, D. T. Jost, U. W. Kirbach, D. M. Lee, H. Nitsche, J. B. Patin, V. Pershina, D. Piguet, Z. Qin, M. Schädel, B. Schausten, E. Schimpf, H.-J. Schött, S. Soverna, R. Sudowe, P. Thörle, S. N. Timokhin, N. Trautmann, A. Türler, A. Vahle, G. Wirth, A. B. Yakushev and P. M. Zielinski

Mantle compensation of active metamorphic core complexes at Woodlark rift in Papua New Guinea pp. 862-865

Geoffrey A. Abers, Aaron Ferris, Mitchell Craig, Hugh Davies, Arthur L. Lerner-Lam, John C. Mutter and Brian Taylor

A mitochondrial remnant in the microsporidian Trachipleistophora hominis pp. 865-869

Bryony A. P. Williams, Robert P. Hirt, John M. Lucocq and T. Martin Embley

Molecular evolution of FOXP2, a gene involved in speech and language pp. 869-872

Wolfgang Enard, Molly Przeworski, Simon E. Fisher, Cecilia S. L. Lai, Victor Wiebe, Takashi Kitano, Anthony P. Monaco and Svante Pääbo

A corollary discharge maintains auditory sensitivity during sound production pp. 872-876

James F. A. Poulet and Berthold Hedwig

Mechanism of magnesium activation of calcium-activated potassium channels pp. 876-880

Jingyi Shi, Gayathri Krishnamoorthy, Yanwu Yang, Lei Hu, Neha Chaturvedi, Dina Harilal, Jun Qin and Jianmin Cui

Multiple regulatory sites in large-conductance calcium-activated potassium channels pp. 880-884

Xiao-Ming Xia, Xuhui Zeng and Christopher J. Lingle

A bacteriolytic agent that detects and kills Bacillus anthracis pp. 884-889

Raymond Schuch, Daniel Nelson and Vincent A. Fischetti

A saponin-detoxifying enzyme mediates suppression of plant defences pp. 889-892

K. Bouarab, R. Melton, J. Peart, D. Baulcombe and A. Osbourn

Patched acts catalytically to suppress the activity of Smoothened pp. 892-896

J. Taipale, M. K. Cooper, T. Maiti and P. A. Beachy

Dynamics of ATP-dependent chromatin assembly by ACF pp. 896-900

Dmitry V. Fyodorov and James T. Kadonaga

2002, volume 418, articles 6899

A decisive effort? pp. 3-3

Paul Smaglik

Small world, big opportunities pp. 4-6

Paul Smaglik

Breaking down biological borders pp. 7-7

Robert Triendl

Senators attack Pentagon over weak state of defence research pp. 711-711

Geoff Brumfiel

Online cheats leave Asian students facing paper exam pp. 711-711

Erika Check

Scientists seek safety in secrets of the soundbite pp. 712-713

David Adam

French minister plans shake-up for research pp. 712-712

Declan Butler and Sally Goodman

Climate model under fire as rains fail India pp. 713-713

K. S. Jayaraman

Top projects suffer as medical funding falters pp. 714-714

Natasha McDowell

Lessons in research aim to win pupils over to science pp. 714-714

Quirin Schiermeier

Troubled waters pp. 718-720

Mark Schrope

Caught on camera pp. 721-722

Rex Dalton

Plant mathematics and Fibonacci's flowers pp. 723-723

Andrew J. Fleming

Macroecology is distinct from biogeography pp. 723-723

Tim M. Blackburn and Kevin J. Gaston

The search for general principles in ecology pp. 723-723

Pablo A. Marquet

Encounters with a dark lady pp. 725-726

David Blow

Record of a revolution pp. 726-727

Adrian Johns

Eco-physiology comes of age pp. 727-727

John Speakman

Protein-misfolding diseases: Getting out of shape pp. 729-730

Christopher M. Dobson

Mass tool for diagnosis pp. 731-732

Matthias Mann

Braking WAVEs pp. 732-733

Giles O. C. Cory and Anne J. Ridley

Mind the double gap pp. 733-734

Warren Pickett

Positive feedback from coffee pp. 734-736

Jean-Marie Vaugeois

Breaking plates pp. 736-737

J. Huw Davies

Signalling legacies pp. 737-738

Richard S. Mann and Fernando Casares

Vote for Little Higgs pp. 738-738

Alison Wright

Scratching the Bose surface pp. 739-740

Subir Sachdev

Muscle regulator goes the distance pp. 740-740

Richard Turner

Surprising strength of silkworm silk pp. 741-741

Zhengzhong Shao and Fritz Vollrath

Thermoregulation in a parasite's life cycle pp. 742-742

Jun Fang and Thomas F. McCutchan

A physical map of the mouse genome pp. 743-750

Simon G. Gregory, Mandeep Sekhon, Jacqueline Schein, Shaying Zhao, Kazutoyo Osoegawa, Carol E. Scott, Richard S. Evans, Paul W. Burridge, Tony V. Cox, Christopher A. Fox, Richard D. Hutton, Ian R. Mullenger, Kimbly J. Phillips, James Smith, Jim Stalker, Glen J. Threadgold, Ewan Birney, Kristine Wylie, Asif Chinwalla, John Wallis, LaDeana Hillier, Jason Carter, Tony Gaige, Sara Jaeger, Colin Kremitzki, Dan Layman, Jason Maas, Rebecca McGrane, Kelly Mead, Rebecca Walker, Steven Jones, Michael Smith, Jennifer Asano, Ian Bosdet, Susanna Chan, Suganthi Chittaranjan, Readman Chiu, Chris Fjell, Dan Fuhrmann, Noreen Girn, Catharine Gray, Ran Guin, Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Soo Sen Lee, Carrie Mathewson, Candice McLeavy, Steve Messervier, Steven Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Duane Smailus, Lorraine Spence, Jeff Stott, Sheryl Taylor, Wesley Terpstra, Miranda Tsai, Jill Vardy, Natasja Wye, George Yang, Sofiya Shatsman, Bola Ayodeji, Keita Geer, Getahun Tsegaye, Alla Shvartsbeyn, Elizabeth Gebregeorgis, Margaret Krol, Daniel Russell, Larry Overton, Joel A. Malek, Mike Holmes, Michael Heaney, Jyoti Shetty, Tamara Feldblyum, William C. Nierman, Joseph J. Catanese, Tim Hubbard, Robert H. Waterston, Jane Rogers, Pieter J. de Jong, Claire M. Fraser, Marco Marra, John D. McPherson and David R. Bentley

Macroscopically ordered state in an exciton system pp. 751-754

L. V. Butov, A. C. Gossard and D. S. Chemla

Long-range transport in excitonic dark states in coupled quantum wells pp. 754-757

D. Snoke, S. Denev, Y. Liu, L. Pfeiffer and K. West

The origin of the anomalous superconducting properties of MgB2 pp. 758-760

Hyoung Joon Choi, David Roundy, Hong Sun, Marvin L. Cohen and Steven G. Louie

The influence of a chemical boundary layer on the fixity, spacing and lifetime of mantle plumes pp. 760-763

A. Mark Jellinek and Michael Manga

Seismic evidence for catastrophic slab loss beneath Kamchatka pp. 763-767

Vadim Levin, Nikolai Shapiro, Jeffrey Park and Michael Ritzwoller

A primitive fish close to the common ancestor of tetrapods and lungfish pp. 767-770

Min Zhu and Xiaobo Yu

Increasing dominance of large lianas in Amazonian forests pp. 770-774

Oliver L. Phillips, Rodolfo Vásquez Martínez, Luzmila Arroyo, Timothy R. Baker, Timothy Killeen, Simon L. Lewis, Yadvinder Malhi, Abel Monteagudo Mendoza, David Neill, Percy Núñez Vargas, Miguel Alexiades, Carlos Cerón, Anthony Di Fiore, Terry Erwin, Anthony Jardim, Walter Palacios, Mario Saldias and Barbara Vinceti

Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine pp. 774-778

Maria Lindskog, Per Svenningsson, Laura Pozzi, Yong Kim, Allen A. Fienberg, James A. Bibb, Bertil B. Fredholm, Angus C. Nairn, Paul Greengard and Gilberto Fisone

Sperm from neonatal mammalian testes grafted in mice pp. 778-781

Ali Honaramooz, Amy Snedaker, Michele Boiani, Hans Schöler, Ina Dobrinski and Stefan Schlatt

Distalization of the Drosophila leg by graded EGF-receptor activity pp. 781-785

Gerard Campbell

Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria pp. 785-789

Louis Schofield, Michael C. Hewitt, Krystal Evans, Mary-Anne Siomos and Peter H. Seeberger

Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck pp. 790-793

Sharon Eden, Rajat Rohatgi, Alexandre V. Podtelejnikov, Matthias Mann and Marc W. Kirschner

Modulation of an RNA-binding protein by abscisic-acid-activated protein kinase pp. 793-797

Jiaxu Li, Toshinori Kinoshita, Sona Pandey, Carl K.-Y. Ng, Steven P. Gygi, Ken-ichiro Shimazaki and Sarah M. Assmann

Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres pp. 797-801

Jiandie Lin, Hai Wu, Paul T. Tarr, Chen-Yu Zhang, Zhidan Wu, Olivier Boss, Laura F. Michael, Pere Puigserver, Eiji Isotani, Eric N. Olson, Bradford B. Lowell, Rhonda Bassel-Duby and Bruce M. Spiegelman

Erratum: A new hominid from the Upper Miocene of Chad, Central Africa pp. 801-801

Michel Brunet, Franck Guy, David Pilbeam, Hassane Taisso Mackaye, Andossa Likius, Djimdoumalbaye Ahounta, Alain Beauvilain, Cécile Blondel, Hervé Bocherens, Jean-Renaud Boisserie, Louis De Bonis, Yves Coppens, Jean Dejax, Christiane Denys, Philippe Duringer, Véra Eisenmann, Gongdibé Fanone, Pierre Fronty, Denis Geraads, Thomas Lehmann, Fabrice Lihoreau, Antoine Louchart, Adoum Mahamat, Gildas Merceron, Guy Mouchelin, Olga Otero, Pablo Pelaez Campomanes, Marcia Ponce De Leon, Jean-Claude Rage, Michel Sapanet, Mathieu Schuster, Jean Sudre, Pascal Tassy, Xavier Valentin, Patrick Vignaud, Laurent Viriot, Antoine Zazzo and Christoph Zollikofer

2002, volume 418, articles 6898

Lessons in career planning pp. 3-3

Paul Smaglik

The Pacific Rim pp. 4-5

Robert Triendl

Africa hungry for conventional food as biotech row drags on pp. 571-572

Natasha McDowell

US calls for early data on transgenic crop safety pp. 571-571

Erika Check

Future of the NIH may lie in restructuring, committee told pp. 572-572

Erika Check

Big projects cited as threat to NSF's integrity pp. 573-573

Geoff Brumfiel

Test-ban treaty 'scientifically sound' pp. 573-573

Geoff Brumfiel

Ink analysis raises storm over Viking map pp. 574-574

John Whitfield and Rex Dalton

Swiss scientists fear for top ranking in basic research pp. 574-574

Oliver Schmidt

It's the ecology, stupid! pp. 578-579

Jennie Dusheck

Who's been looking at your data? pp. 580-582

Declan Butler

Classic detective puts his finger on the clue pp. 583-583

David Ehrenfeld

Microcredit tackles both poverty and birthrate pp. 583-583

Michael E. McIntyre

Israeli terms are used for consistency, not politics pp. 583-583

Amnon Freidberg and Ilan Yarom

Bioethics: centres reveal sponsors but not policy pp. 583-583

Virginia Ashby Sharpe

DNA testing for all pp. 585-586

Robert Williamson and Rony Duncan

Putting Egypt back on the map pp. 587-588

A.B. Zahlan

Quantifying bird diversity pp. 588-589

Arie J. van Noordwijk

Thinking laterally about genes pp. 589-590

W. Ford Doolittle

Science in culture pp. 590-590

Martin Kemp

Desensitization: Diminishing returns pp. 591-591

Henrik G. Dohlman

Uncertain sinks in the shrubs pp. 593-594

Christine L. Goodale and Eric A. Davidson

A tough viral nut to crack pp. 594-595

Roger J. Pomerantz

Keeping hunger at bay pp. 595-597

Michael W. Schwartz and Gregory J. Morton

One at a time, please pp. 597-598

Manfred Bayer

Calcium callisthenics pp. 598-599

N. Michael Green and David H. MacLennan

W. Maxwell Cowan (1931–2002) pp. 600-600

David C. Van Essen and Joseph L. Price

Contrails reduce daily temperature range pp. 601-601

David J. Travis, Andrew M. Carleton and Ryan G. Lauritsen

Male parenting of New Guinea froglets pp. 601-602

David Bickford

Black holes constrain varying constants pp. 602-603

P. C. W. Davies, Tamara M. Davis and Charles H. Lineweaver

Gliding flight in the paradise tree snake pp. 603-604

John J. Socha

What governs nitrogen loss from forest soils? pp. 604-604

Tom Addiscott and Phil Brookes

What governs nitrogen loss from forest soils? pp. 604-604

Nico van Breemen

Structural changes in the calcium pump accompanying the dissociation of calcium pp. 605-611

Chikashi Toyoshima and Hiromi Nomura

Coherent properties of a two-level system based on a quantum-dot photodiode pp. 612-614

A. Zrenner, E. Beham, S. Stufler, F. Findeis, M. Bichler and G. Abstreiter

Evidence for spin–charge separation in quasi-one-dimensional organic conductors pp. 614-617

T. Lorenz, M. Hofmann, M. Grüninger, A. Freimuth, G. S. Uhrig, M. Dumm and M. Dressel

Sub-ångstrom resolution using aberration corrected electron optics pp. 617-620

P. E. Batson, N. Dellby and O. L. Krivanek

Experimental evidence for sub-3-fs charge transfer from an aromatic adsorbate to a semiconductor pp. 620-623

Joachim Schnadt, Paul A. Brühwiler, Luc Patthey, James N. O'Shea, Sven Södergren, Michael Odelius, Rajeev Ahuja, Olof Karis, Margit Bässler, Petter Persson, Hans Siegbahn, S. Lunell and Nils Mårtensson

Ecosystem carbon loss with woody plant invasion of grasslands pp. 623-626

Robert B. Jackson, Jay L. Banner, Esteban G. Jobbágy, William T. Pockman and Diana H. Wall

Reassessing the evidence for the earliest traces of life pp. 627-630

Mark A. van Zuilen, Aivo Lepland and Gustaf Arrhenius

Cultivation of the ubiquitous SAR11 marine bacterioplankton clade pp. 630-633

Michael S. Rappé, Stephanie A. Connon, Kevin L. Vergin and Stephen J. Giovannoni

An unexpected specialization for horizontal disparity in primate primary visual cortex pp. 633-636

B. G. Cumming

Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis pp. 636-641

Petra Pandur, Matthias Läsche, Leonard M. Eisenberg and Michael Kühl

A component of the ARC/Mediator complex required for TGFβ/Nodal signalling pp. 641-646

Yoichi Kato, Raymond Habas, Yu Katsuyama, Anders M. Näär and Xi He

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein pp. 646-650

Ann M. Sheehy, Nathan C. Gaddis, Jonathan D. Choi and Michael H. Malim

Gut hormone PYY3-36 physiologically inhibits food intake pp. 650-654

Rachel L. Batterham, Michael A. Cowley, Caroline J. Small, Herbert Herzog, Mark A. Cohen, Catherine L. Dakin, Alison M. Wren, Audrey E. Brynes, Malcolm J. Low, Mohammad A. Ghatei, Roger D. Cone and Stephen R. Bloom

A naturally occurring MTA1 variant sequesters oestrogen receptor-α in the cytoplasm pp. 654-657

Rakesh Kumar, Rui-An Wang, Abhijit Mazumdar, Amjad H. Talukder, Mahitosh Mandal, Zhibo Yang, Rozita Bagheri-Yarmand, Aysegul Sahin, Gabriel Hortobagyi, Liana Adam, Christopher J. Barnes and Ratna K. Vadlamudi

Biomimetic synthesis and optimization of cyclic peptide antibiotics pp. 658-661

Rahul M. Kohli, Christopher T. Walsh and Michael D. Burkart

Three-dimensional structure of the bacterial protein-translocation complex SecYEG pp. 662-665

Cécile Breyton, Winfried Haase, Tom A. Rapoport, Werner Kühlbrandt and Ian Collinson

addendum: Nitrogen loss from unpolluted South American forests mainly via dissolved organic compounds pp. 665-665

Steven S. Perakis and Lars O. Hedin

Correction: Corrigendum: Extensive and divergent circadian gene expression in liver and heart pp. 665-665

Kai-Florian Storch, Ovidiu Lipan, Igor Leykin, N. Viswanathan, Fred C. Davis, Wing H. Wong and Charles J. Weitz

Food & the future pp. 667-667

Henry Gee

Malthus foiled again and again pp. 668-670

Antony Trewavas

Agricultural sustainability and intensive production practices pp. 671-677

David Tilman, Kenneth G. Cassman, Pamela A. Matson, Rosamond Naylor and Stephen Polasky

Enhancing the crops to feed the poor pp. 678-684

Jikun Huang, Carl Pray and Scott Rozelle

Assessing the risks associated with new agricultural practices pp. 685-688

R. S. Hails

Towards sustainability in world fisheries pp. 689-695

Daniel Pauly, Villy Christensen, Sylvie Guénette, Tony J. Pitcher, Ussif Sumaila, Carl J. Walters, R. Watson and Dirk Zeller

The present and future of the international wine industry pp. 696-699

Linda F. Bisson, Andrew L. Waterhouse, Susan E. Ebeler, M. Andrew Walker and James T. Lapsley

Evolution, consequences and future of plant and animal domestication pp. 700-707

Jared Diamond

2002, volume 418, articles 6897

Fresh paths in Europe pp. 3-3

Paul Smaglik

Row over neutron source hots up as Germany's advisers cry foul pp. 467-467

Quirin Schiermeier

Accused obesity researcher returns to the French fold pp. 467-467

Declan Butler

Falling share price stymies gift to university pp. 468-468

Rex Dalton

Asteroid rating system makes an impact on the media pp. 468-468

Jonathan Knight

Model success is not the end of the matter pp. 469-469

Geoff Brumfiel

'Superbug' hurdles key drug barrier pp. 469-469

Helen Pearson

Biomedical institute suffers growing pains pp. 470-470

Erika Check

Opponents of stem-cell patent win restrictions pp. 470-470

Alison Abbott and Oliver Schmidt

Honey, I shrunk the lab pp. 474-475

Jonathan Knight

When doubt is a sure thing pp. 476-478

Jim Giles

DNA points the way ahead in taxonomy pp. 479-479

Diethard Tautz, Peter Arctander, Alessandro Minelli, Richard H. Thomas and Alfried P. Vogler

Israeli concern about Palestinian suffering pp. 479-479

Victoria Buch

Science council replies to neutron claims pp. 479-479

Karl Max Einhäupl

A whole new world of geology pp. 481-482

Greg Bear

A historian of Victorian astronomy pp. 482-483

Donald E. Osterbrock

A bestial feast pp. 483-483

Tim Birkhead

Antibody catalysis: Completing the circle pp. 485-485

P. G. Schultz and R. A. Lerner

Impacts in the round pp. 487-488

John G. Spray

Never fear, cannabinoids are here pp. 488-489

Pankaj Sah

Core values pp. 489-491

John Brodholt and Francis Nimmo

Zeolites branch out pp. 491-491

Rosamund Daw

Making progress with limb models pp. 492-493

Denis Duboule

Ultrafast magnetic switching pp. 493-495

Burkard Hillebrands and Jürgen Fassbender

Oscillation sensation pp. 495-496

David O. Morgan and James M. Roberts

Maturation of mouse fetal germ cells in vitro pp. 497-497

Yayoi Obata, Tomohiro Kono and Izuho Hatada

Trans-histone regulatory pathway in chromatin pp. 498-498

Scott D. Briggs, Tiaojiang Xiao, Zu-Wen Sun, Jennifer A. Caldwell, Jeffrey Shabanowitz, Donald F. Hunt, C. David Allis and Brian D. Strahl

Does similarity breed cooperation? pp. 499-500

Gilbert Roberts and Thomas N. Sherratt

Supernova-remnant origin of cosmic rays? pp. 499-499

Yousaf M. Butt, Diego F. Torres, Gustavo E. Romero, Thomas M. Dame and Jorge A. Combi

Does similarity breed cooperation? pp. 500-500

Rick L. Riolo, Michael Cohen and Robert Axelrod

Functions of FGF signalling from the apical ectodermal ridge in limb development pp. 501-508

Xin Sun, Francesca V. Mariani and Gail R. Martin

Ultrafast precessional magnetization reversal by picosecond magnetic field pulse shaping pp. 509-512

Th. Gerrits, H. A. M. van den Berg, J. Hohlfeld, L. Bär and Th. Rasing

Single-pulse coherently controlled nonlinear Raman spectroscopy and microscopy pp. 512-514

Nirit Dudovich, Dan Oron and Yaron Silberberg

A large-cavity zeolite with wide pore windows and potential as an oil refining catalyst pp. 514-517

Avelino Corma, María J. Díaz-Cabañas, Joaquín Martínez-Triguero, Fernando Rey and Jordi Rius

Lamellar magnetism in the haematite–ilmenite series as an explanation for strong remanent magnetization pp. 517-520

Peter Robinson, Richard J. Harrison, Suzanne A. McEnroe and Robert B. Hargraves

A 20-km-diameter multi-ringed impact structure in the North Sea pp. 520-523

Simon A. Stewart and Philip J. Allen

The evolution of inaccurate mimics pp. 524-526

Rufus A. Johnstone

Fractal geometry predicts varying body size scaling relationships for mammal and bird home ranges pp. 527-530

John P. Haskell, Mark E. Ritchie and Han Olff

The endogenous cannabinoid system controls extinction of aversive memories pp. 530-534

Giovanni Marsicano, Carsten T. Wotjak, Shahnaz C. Azad, Tiziana Bisogno, Gerhard Rammes, Maria Grazia Cascio, Heike Hermann, Jianrong Tang, Clementine Hofmann, Walter Zieglgänsberger, Vincenzo Di Marzo and Beat Lutz

A transcription factor response element for gene expression during circadian night pp. 534-539

Hiroki R. Ueda, Wenbin Chen, Akihito Adachi, Hisanori Wakamatsu, Satoko Hayashi, Tomohiro Takasugi, Mamoru Nagano, Ken-ichi Nakahama, Yutaka Suzuki, Sumio Sugano, Masamitsu Iino, Yasufumi Shigeyoshi and Seiichi Hashimoto

A re-examination of proximodistal patterning during vertebrate limb development pp. 539-544

Andrew T. Dudley, María A. Ros and Clifford J. Tabin

A first-generation linkage disequilibrium map of human chromosome 22 pp. 544-548

Elisabeth Dawson, Gonçalo R. Abecasis, Suzannah Bumpstead, Yuan Chen, Sarah Hunt, David M. Beare, Jagjit Pabial, Thomas Dibling, Emma Tinsley, Susan Kirby, David Carter, Marianna Papaspyridonos, Simon Livingstone, Rocky Ganske, Elin Lõhmussaar, Jana Zernant, Neeme Tõnisson, Maido Remm, Reedik Mägi, Tarmo Puurand, Jaak Vilo, Ants Kurg, Kate Rice, Panos Deloukas, Richard Mott, Andres Metspalu, David R. Bentley, Lon R. Cardon and Ian Dunham

Golgi biogenesis in Toxoplasma gondii pp. 548-552

Laurence Pelletier, Charlene A. Stern, Marc Pypaert, David Sheff, Huân M. Ngô, Nitin Roper, Cynthia Y. He, Ke Hu, Derek Toomre, Isabelle Coppens, David S. Roos, Keith A. Joiner and Graham Warren

Two-step binding mechanism for T-cell receptor recognition of peptide–MHC pp. 552-556

Lawren C. Wu, Delphine S. Tuot, Daniel S. Lyons, K. Christopher Garcia and Mark M. Davis

APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit pp. 556-562

Ralph Wäsch and Frederick R. Cross

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair pp. 562-566

Karl-Peter Hopfner, Lisa Craig, Gabriel Moncalian, Robert A. Zinkel, Takehiko Usui, Barbara A. L. Owen, Annette Karcher, Brendan Henderson, Jean-Luc Bodmer, Cynthia T. McMurray, James P. Carney, John H. J. Petrini and John A. Tainer

2002, volume 418, articles 6896

Working with the Framework pp. 3-3

Paul Smaglik

Biotech firms spurn university site pp. 355-355

Rex Dalton

Geneticist fears 'race-neutral' studies will fail ethnic groups pp. 355-356

Peter Aldhous

Bioethics council demands tighter rules on gene patents pp. 356-356

David Adam

Biologists angered by database access fee pp. 357-357

Alison Abbott

Japan gives scientists political role pp. 357-357

David Cyranoski

Lords blast red tape in animal experiments pp. 358-358

Natasha McDowell

US labs bemoan lack of stem cells pp. 358-358

Kendall Powell

Futurists predict body swaps for planet hops pp. 359-359

Geoff Brumfiel

Imbalance a sticky issue among stamps of distinction pp. 359-359

David Adam

All living things, online pp. 362-363

Virginia Gewin

The virtue of tolerance pp. 364-366

Erika Check

Taxonomy, at the click of a mouse pp. 367-367

Frank A. Bisby, Junko Shimura, Michael Ruggiero, James Edwards and Christoph Haeuser

Strong case for neutrons pp. 367-367

B. Keimer

The question of animal rights pp. 369-370

Diana Reiss

Replication at the speed of thought pp. 370-371

Eörs Szathmáry

Running through the mind pp. 371-371

Norman Myers

Water management: Soft water paths pp. 373-373

Peter H. Gleick

Much binding in the lab pp. 375-376

Andrew D. Hamilton

Full circle to cobbled brain pp. 376-377

M. Elizabeth Ross

Spaced-out electrons pp. 377-379

John C. H. Spence

Silencing viruses with RNA pp. 379-380

Gordon G. Carmichael

Inside a micro-reactor pp. 381-383

Detlef Lohse

Springboards for springtails pp. 381-381

Peter D. Moore

Inherit the wheeze pp. 383-384

Jeffrey M. Drazen and Scott T. Weiss

Magnetic shape-memory effects in a crystal pp. 385-386

A. N. Lavrov, Seiki Komiya and Yoichi Ando

Screening inhibitors of anthrax lethal factor pp. 386-386

Fiorella Tonello, Michela Seveso, Oriano Marin, Michèle Mock and Cesare Montecucco

Functional profiling of the Saccharomyces cerevisiae genome pp. 387-391

Guri Giaever, Angela M. Chu, Li Ni, Carla Connelly, Linda Riles, Steeve Véronneau, Sally Dow, Ankuta Lucau-Danila, Keith Anderson, Bruno André, Adam P. Arkin, Anna Astromoff, Mohamed El Bakkoury, Rhonda Bangham, Rocio Benito, Sophie Brachat, Stefano Campanaro, Matt Curtiss, Karen Davis, Adam Deutschbauer, Karl-Dieter Entian, Patrick Flaherty, Francoise Foury, David J. Garfinkel, Mark Gerstein, Deanna Gotte, Ulrich Güldener, Johannes H. Hegemann, Svenja Hempel, Zelek Herman, Daniel F. Jaramillo, Diane E. Kelly, Steven L. Kelly, Peter Kötter, Darlene LaBonte, David C. Lamb, Ning Lan, Hong Liang, Hong Liao, Lucy Liu, Chuanyun Luo, Marc Lussier, Rong Mao, Patrice Menard, Siew Loon Ooi, Jose L. Revuelta, Christopher J. Roberts, Matthias Rose, Petra Ross-Macdonald, Bart Scherens, Greg Schimmack, Brenda Shafer, Daniel D. Shoemaker, Sharon Sookhai-Mahadeo, Reginald K. Storms, Jeffrey N. Strathern, Giorgio Valle, Marleen Voet, Guido Volckaert, Ching-yun Wang, Teresa R. Ward, Julie Wilhelmy, Elizabeth A. Winzeler, Yonghong Yang, Grace Yen, Elaine Youngman, Kexin Yu, Howard Bussey, Jef D. Boeke, Michael Snyder, Peter Philippsen, Ronald W. Davis and Mark Johnston

Observation of Hanbury Brown–Twiss anticorrelations for free electrons pp. 392-394

Harald Kiesel, Andreas Renz and Franz Hasselbach

The energy efficiency of formation of photons, radicals and ions during single-bubble cavitation pp. 394-397

Yuri T. Didenko and Kenneth S. Suslick

Equilibrium lithium transport between nanocrystalline phases in intercalated TiO2 anatase pp. 397-399

M. Wagemaker, A. P. M. Kentgens and F. M. Mulder

Synthetic hosts by monomolecular imprinting inside dendrimers pp. 399-403

Steven C. Zimmerman, Michael S. Wendland, Neal A. Rakow, Ilya Zharov and Kenneth S. Suslick

Tungsten isotope evidence from ∼3.8-Gyr metamorphosed sediments for early meteorite bombardment of the Earth pp. 403-405

Ronny Schoenberg, Balz S. Kamber, Kenneth D. Collerson and Stephen Moorbath

A long-tailed, seed-eating bird from the Early Cretaceous of China pp. 405-409

Zhonghe Zhou and Fucheng Zhang

Mechanisms of long-distance dispersal of seeds by wind pp. 409-413

Ran Nathan, Gabriel G. Katul, Henry S. Horn, Suvi M. Thomas, Ram Oren, Roni Avissar, Stephen W. Pacala and Simon A. Levin

A neural correlate of response bias in monkey caudate nucleus pp. 413-417

Johan Lauwereyns, Katsumi Watanabe, Brian Coe and Okihide Hikosaka

Post-translational disruption of dystroglycan–ligand interactions in congenital muscular dystrophies pp. 417-421

Daniel E. Michele, Rita Barresi, Motoi Kanagawa, Fumiaki Saito, Ronald D. Cohn, Jakob S. Satz, James Dollar, Ichizo Nishino, Richard I. Kelley, Hannu Somer, Volker Straub, Katherine D. Mathews, Steven A. Moore and Kevin P. Campbell

Deletion of brain dystroglycan recapitulates aspects of congenital muscular dystrophy pp. 422-425

Steven A. Moore, Fumiaki Saito, Jianguo Chen, Daniel E. Michele, Michael D. Henry, Albee Messing, Ronald D. Cohn, Susan E. Ross-Barta, Steve Westra, Roger A. Williamson, Toshinori Hoshi and Kevin P. Campbell

Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness pp. 426-430

Paul Van Eerdewegh, Randall D. Little, Josée Dupuis, Richard G. Del Mastro, Kathy Falls, Jason Simon, Dana Torrey, Sunil Pandit, Joyce McKenny, Karen Braunschweiger, Alison Walsh, Ziying Liu, Brooke Hayward, Colleen Folz, Susan P. Manning, Alicia Bawa, Lisa Saracino, Michelle Thackston, Youssef Benchekroun, Neva Capparell, Mei Wang, Ron Adair, Yun Feng, JoAnn Dubois, Michael G. FitzGerald, Hui Huang, René Gibson, Kristina M. Allen, Alex Pedan, Melvyn R. Danzig, Shelby P. Umland, Robert W. Egan, Francis M. Cuss, Steuart Rorke, Joanne B. Clough, John W. Holloway, Stephen T. Holgate and Tim P. Keith

Short interfering RNA confers intracellular antiviral immunity in human cells pp. 430-434

Leonid Gitlin, Sveta Karelsky and Raul Andino

Modulation of HIV-1 replication by RNA interference pp. 435-438

Jean-Marc Jacque, Karine Triques and Mario Stevenson

E3 ubiquitin ligase that recognizes sugar chains pp. 438-442

Yukiko Yoshida, Tomoki Chiba, Fuminori Tokunaga, Hiroshi Kawasaki, Kazuhiro Iwai, Toshiaki Suzuki, Yukishige Ito, Koji Matsuoka, Minoru Yoshida, Keiji Tanaka and Tadashi Tai

Distinct molecular mechanism for initiating TRAF6 signalling pp. 443-447

Hong Ye, Joseph R. Arron, Betty Lamothe, Maurizio Cirilli, Takashi Kobayashi, Nirupama K. Shevde, Deena Segal, Oki K. Dzivenu, Masha Vologodskaia, Mijung Yim, Khoi Du, Sujay Singh, J. Wesley Pike, Bryant G. Darnay, Yongwon Choi and Hao Wu

Erratum: Regulation of Arabidopsis cryptochrome 2 by blue-light-dependent phosphorylation pp. 447-447

Dror Shalitin, Hongyun Yang, Todd C. Mockler, Maskit Maymon, Hongwei Guo, Garry C. Whitelam and Chentao Lin

Screening for drug discovery: The leading question pp. 453-455

Adam Smith

Automating the screening process pp. 453-453

Adam Smith

Getting to know the family pp. 455-455

Adam Smith

How small should you go? pp. 457-457

Adam Smith

Fragmenting the problem pp. 459-459

Adam Smith

2002, volume 418, articles 6895

A dual existence pp. 3-3

Paul Smaglik

Government spending promise offers British research a boost pp. 261-261

David Adam and Natasha McDowell

California lab fires physicist over retracted finding pp. 261-261

Rex Dalton

German council confounds plans for neutron project pp. 262-262

Quirin Schiermeier

Senate nod prompts fresh analysis of nuclear waste dump pp. 262-262

Geoff Brumfiel

Cutbacks 'will cripple space station science' pp. 263-263

Tony Reichhardt

NASA aims to reach Pluto by 2020 pp. 263-263

Tony Reichhardt

Publishers soldier on despite electronic bugs pp. 264-264

Rex Dalton

US panel split on research cloning pp. 264-264

Kendall Powell

Poliovirus advance sparks fears of data curbs pp. 265-265

Erika Check

Monkey smallpox trial suspended over painkiller use pp. 265-265

Erika Check

They said it couldn't be done pp. 268-269

Alison Abbott

Can you keep a secret? pp. 270-272

Erica Klarreich

Names: a historical or political perspective? pp. 273-273

Sharona Even-Ram

Only vital need justifies primate experiments pp. 273-273

Richard M. Lebovitz

Little funding to develop non-animal testing pp. 273-273

Gill Langley

Are results of primate research worth the suffering it causes? pp. 273-273

Michelle Thew

Viewing life as cooperation pp. 275-276

Axel Meyer

Unravelling a heavenly mystery pp. 276-277

Luigi Piro

Darwin's personal voyage pp. 277-278

Keith Thomson

Science in culture pp. 278-278

Martin Kemp

Development: Weaving life's pattern pp. 279-279

Melvin Konner

Survival of the entangled pp. 281-282

William Barnes

Decisions, decisions! pp. 282-283

Brigid Hogan

Malaria variorum pp. 283-284

Andrew G. Clark

Plastic parameter pp. 285-286

Jonathan A. Zimmerman

The extraordinary phagosome pp. 286-287

Joel A. Swanson

Don't hold your breath pp. 287-288

Siu Sylvia Lee and Gary Ruvkun

Cacao usage by the earliest Maya civilization pp. 289-290

W. Jeffrey Hurst, Stanley M. Tarka, Terry G. Powis, Fred Valdez and Thomas R. Hester

Targeted transfection by femtosecond laser pp. 290-291

Uday K. Tirlapur and Karsten König

Recent temperature trends in the Antarctic pp. 291-292

John Turner, John C. King, Tom A. Lachlan-Cope and Phil D. Jones

Amyloid pores from pathogenic mutations pp. 291-291

Hilal A. Lashuel, Dean Hartley, Benjamin M. Petre, Thomas Walz and Peter T. Lansbury

Recent temperature trends in the Antarctic pp. 292-292

J. E. Walsh, P. T. Doran, J. C. Priscu, W. B. Lyons, A. G. Fountain, D. M. McKnight, D. L. Moorhead, R. A. Virginia, D. H. Wall, G. D. Clow, C. H. Fritsen, C. P. McKay and A. N. Parsons

A molecular programme for the specification of germ cell fate in mice pp. 293-300

Mitinori Saitou, Sheila C. Barton and M. Azim Surani

Hot bubbles from active galactic nuclei as a heat source in cooling-flow clusters pp. 301-303

Marcus Brüggen and Christian R. Kaiser

Plasmon-assisted transmission of entangled photons pp. 304-306

E. Altewischer, M. P. van Exter and J. P. Woerdman

Atomistic mechanisms governing elastic limit and incipient plasticity in crystals pp. 307-310

Ju Li, Krystyn J. Van Vliet, Ting Zhu, Sidney Yip and Subra Suresh

Dynamic fracture by large extraterrestrial impacts as the origin of shatter cones pp. 310-313

Amir Sagy, Ze'ev Reches and Jay Fineberg

Climate-mediated energetic constraints on the distribution of hibernating mammals pp. 313-316

Murray M. Humphries, Donald W. Thomas and John R. Speakman

An antioxidant function for DMSP and DMS in marine algae pp. 317-320

W. Sunda, D. J. Kieber, R. P. Kiene and S. Huntsman

Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum pp. 320-323

John C. Wootton, Xiaorong Feng, Michael T. Ferdig, Roland A. Cooper, Jianbing Mu, Dror I. Baruch, Alan J. Magill and Xin-zhuan Su

Chromosome-wide SNPs reveal an ancient origin for Plasmodium falciparum pp. 323-324

Jianbing Mu, Junhui Duan, Kateryna D. Makova, Deirdre A. Joy, Chuong Q. Huynh, Oralee H. Branch, Wen-Hsiung Li and Xin-zhuan Su

Dendritic spikes as a mechanism for cooperative long-term potentiation pp. 326-331

Nace L. Golding, Nathan P. Staff and Nelson Spruston

Identification of genes expressed in C. elegans touch receptor neurons pp. 331-335

Yun Zhang, Charles Ma, Thomas Delohery, Brian Nasipak, Barrett C. Foat, Alexander Bounoutas, Harmen J. Bussemaker, Stuart K. Kim and Martin Chalfie

Synaptotagmins I and IV promote transmitter release independently of Ca2+ binding in the C2A domain pp. 336-340

Iain M. Robinson, Ravi Ranjan and Thomas L. Schwarz

The C2B Ca2+-binding motif of synaptotagmin is required for synaptic transmission in vivo pp. 340-344

J. M. Mackler, J. A. Drummond, C. A. Loewen, I. M. Robinson and N. E. Reist

Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration pp. 344-348

Su-Ju Lin, Matt Kaeberlein, Alex A. Andalis, Lori A. Sturtz, Pierre-Antoine Defossez, Valeria C. Culotta, Gerald R. Fink and Leonard Guarente

Adenovirus oncoproteins inactivate the Mre11–Rad50–NBS1 DNA repair complex pp. 348-352

Travis H. Stracker, Christian T. Carson and Matthew D. Weitzman

Correction: Corrigendum: The mammalian sodium channel BNC1 is required for normal touch sensation pp. 352-352

Margaret P. Price, Gary R. Lewin, Sabrina L. Mcllwrath, Chun Cheng, Jinghul Xie, Paul A. Heppenstall, Cheryl L. Stucky, Anne G. Mannsfeldt, Timothy J. Brennan, Heather A. Drummond, Jing Qiao, Christopher J. Benson, Deirdre E. Tarr, Ron F. Hrstka, Baoll Yang, Roger A. Williamson and Michael J. Walsh

2002, volume 418, articles 6894

A chemical imbalance pp. 3-3

Paul Smaglik

Gaining a lot from translation pp. 5-5

Jan Schmollinger

Dubious data remain in print two years after misconduct inquiry pp. 113-113

Alison Abbott and Johanna Schwarz

Europe gets tough on labelling genetically modified foodstuffs pp. 114-114

Declan Butler

Botswana's AIDS laboratory squares up to HIV pandemic pp. 114-114

Michael Cherry

AIDS meeting demands more than lip service pp. 115-115

Declan Butler

Biology project left short of cash pp. 115-115

David Cyranoski

Race is on to find alternative to animal tests pp. 116-116

Sally Goodman

Japan lays out 55-point patent plan pp. 116-116

David Cyranoski

Physicists plot mass production of neutrinos pp. 117-117

David Adam

Public body appointed to clean up UK's nuclear legacy pp. 117-117

David Adam

Time to wise up? pp. 120-121

Geoff Brumfiel

The brave new world of RNA pp. 122-124

Carina Dennis

Interoperability calls for an unusual mix of skills pp. 125-125

Fabien Campagne

Rebel army need not be a barrier to conservation pp. 125-125

Craig Turner and Pete Raines

Jury out on Jefferson's alleged descendants pp. 125-125

Steven T. Corneliussen

Networking comes of age pp. 127-128

Sidney Redner

A right royal feud pp. 128-129

Owen Gingerich

Evolution by design? pp. 129-129

Brian Charlesworth

Complexity: The bigger picture pp. 131-131

Tamas Vicsek

Hominid revelations from Chad pp. 133-135

Bernard Wood

Out on the edge pp. 135-137

William B. McKinnon

Do the locomotion pp. 137-137

Roger V. Short

Bacterial game dynamics pp. 138-139

Martin A. Nowak and Karl Sigmund

Cleaning up catalysts pp. 138-138

Magdalena Helmer

Repulsive encounters pp. 139-141

Giovanna Chimini

Ants on a Turing trail pp. 141-142

Peter Hammerstein and Olof Leimar

Snake circumvents constraints on prey size pp. 143-143

Bruce C. Jayne, Harold K. Voris and Peter K. L. Ng

Multiply infected spleen cells in HIV patients pp. 144-144

Andreas Jung, Reinhard Maier, Jean-Pierre Vartanian, Gennady Bocharov, Volker Jung, Ulrike Fischer, Eckart Meese, Simon Wain-Hobson and Andreas Meyerhans

A new hominid from the Upper Miocene of Chad, Central Africa pp. 145-151

Michel Brunet, Franck Guy, David Pilbeam, Hassane Taisso Mackaye, Andossa Likius, Djimdoumalbaye Ahounta, Alain Beauvilain, Cécile Blondel, Hervé Bocherens, Jean-Renaud Boisserie, Louis De Bonis, Yves Coppens, Jean Dejax, Christiane Denys, Philippe Duringer, Véra Eisenmann, Gongdibé Fanone, Pierre Fronty, Denis Geraads, Thomas Lehmann, Fabrice Lihoreau, Antoine Louchart, Adoum Mahamat, Gildas Merceron, Guy Mouchelin, Olga Otero, Pablo Pelaez Campomanes, Marcia Ponce De Leon, Jean-Claude Rage, Michel Sapanet, Mathieu Schuster, Jean Sudre, Pascal Tassy, Xavier Valentin, Patrick Vignaud, Laurent Viriot, Antoine Zazzo and Christoph Zollikofer

Geology and palaeontology of the Upper Miocene Toros-Menalla hominid locality, Chad pp. 152-155

Patrick Vignaud, Philippe Duringer, Hassane Taïsso Mackaye, Andossa Likius, Cécile Blondel, Jean-Renaud Boisserie, Louis de Bonis, Véra Eisenmann, Marie-Esther Etienne, Denis Geraads, Franck Guy, Thomas Lehmann, Fabrice Lihoreau, Nieves Lopez-Martinez, Cécile Mourer-Chauviré, Olga Otero, Jean-Claude Rage, Mathieu Schuster, Laurent Viriot, Antoine Zazzo and Michel Brunet

Possible in situ formation of meteoritic nanodiamonds in the early Solar System pp. 157-159

Z. R. Dai, J. P. Bradley, D. J. Joswiak, D. E. Brownlee, H. G. M. Hill and M. J. Genge

Phonon-enhanced light–matter interaction at the nanometre scale pp. 159-162

R. Hillenbrand, T. Taubner and F. Keilmann

Pressure-induced insulator–conductor transition in a photoconducting organic liquid-crystal film pp. 162-164

Chong-yang Liu and Allen J. Bard

Self-regeneration of a Pd-perovskite catalyst for automotive emissions control pp. 164-167

Y. Nishihata, J. Mizuki, T. Akao, H. Tanaka, M. Uenishi, M. Kimura, T. Okamoto and N. Hamada

A satellite geodetic survey of large-scale deformation of volcanic centres in the central Andes pp. 167-171

Matthew E. Pritchard and Mark Simons

Local dispersal promotes biodiversity in a real-life game of rock–paper–scissors pp. 171-174

Benjamin Kerr, Margaret A. Riley, Marcus W. Feldman and Brendan J. M. Bohannan

Exceptional sperm cooperation in the wood mouse pp. 174-177

Harry Moore, Katerina Dvoráková, Nicholas Jenkins and William Breed

Transmitter-evoked local calcium release stabilizes developing dendrites pp. 177-181

Christian Lohmann, Karen L. Myhr and Rachel O. L. Wong

TRPV3 is a calcium-permeable temperature-sensitive cation channel pp. 181-186

Haoxing Xu, I. Scott Ramsey, Suhas A. Kotecha, Magdalene M. Moran, Jayhong A. Chong, Deborah Lawson, Pei Ge, Jeremiah Lilly, Inmaculada Silos-Santiago, Yu Xie, Peter S. DiStefano, Rory Curtis and David E. Clapham

TRPV3 is a temperature-sensitive vanilloid receptor-like protein pp. 186-190

G. D. Smith, M. J. Gunthorpe, R. E. Kelsell, P. D. Hayes, P. Reilly, P. Facer, J. E. Wright, J. C. Jerman, J.-P. Walhin, L. Ooi, J. Egerton, K. J. Charles, D. Smart, A. D. Randall, P. Anand and J. B. Davis

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation pp. 191-195

Paola Scaffidi, Tom Misteli and Marco E. Bianchi

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes pp. 195-199

Tian H. Chi, Mimi Wan, Keji Zhao, Ichiro Taniuchi, Lei Chen, Dan R. Littman and Gerald R. Crabtree

Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment pp. 200-203

Simon Brown, Isabelle Heinisch, Ewan Ross, Kate Shaw, Chris D. Buckley and John Savill

Overexpression of β-carotene hydroxylase enhances stress tolerance in Arabidopsis pp. 203-206

P. A. Davison, C. N. Hunter and P. Horton

NMR analysis of a 900K GroEL–GroES complex pp. 207-211

Jocelyne Fiaux, Eric B. Bertelsen, Arthur L. Horwich and Kurt Wüthrich

Erratum: Optical pulsations from the anomalous X-ray pulsar 4U0142+61 pp. 211-211

B. Kern and C. Martin

RNA pp. 213-213

Richard Turner

The antiquity of RNA-based evolution pp. 214-221

Gerald F. Joyce

The chemical repertoire of natural ribozymes pp. 222-228

Jennifer A. Doudna and Thomas R. Cech

The involvement of RNA in ribosome function pp. 229-235

Peter B. Moore and Thomas A. Steitz

Alternative pre-mRNA splicing and proteome expansion in metazoans pp. 236-243

Tom Maniatis and Bosiljka Tasic

RNA interference pp. 244-251

Gregory J. Hannon

Emerging clinical applications of RNA pp. 252-258

Bruce A. Sullenger and Eli Gilboa

2002, volume 418, articles 6893

Fire-fighting senators move to set up wildfire research institutes pp. 3-4

Tony Reichhardt

Top physics lab names its leader pp. 3-3

David Cyranoski

The chips are down pp. 3-3

Paul Smaglik

Riding the biotech rollercoaster pp. 4-5

Paul Smaglik and Adam Smith

Visitors to AIDS conference trapped in web of red tape pp. 4-4

Declan Butler

Gulf War syndrome research poised for cash injection pp. 4-4

Jonathan Knight

Bell Labs inquiry spreads to superconductors pp. 5-5

Geoff Brumfiel

Biotech woes set to hit academics pp. 5-5

Jonathan Knight

Recriminations inflame UK research debate pp. 6-6

David Adam

Angry scientists march on Moscow in budget protest pp. 6-6

Bryon MacWilliams

US exchange scheme offers a taste of Europe pp. 7-7

Quirin Schiermeier

France hails milestone in start-ups pp. 7-7

Sally Goodman

Picture this pp. 11-13

Philip Ball

Your destiny, from day one pp. 14-15

Helen Pearson

Population should be on the Johannesburg agenda pp. 17-17

Wolfgang Lutz and Mahendra Shah

Beautiful vistas, but is this really science? pp. 17-17

Michael Phillips

Solve postgrad problems to attract new scientists pp. 17-17

T. L. Raoul Tan and Simone Lohner

Evolution under pressure pp. 19-20

Jerry A. Coyne

Competition between women pp. 20-21

Elizabeth Cashdan

Science in culture pp. 21-21

David Cyranoski

Ionosphere: High above the Earth pp. 23-23

Henry Rishbeth

Stem-cell competition pp. 25-26

Stuart H. Orkin and Sean J. Morrison

An older face for Mars pp. 27-28

Sean C. Solomon

Fluid flow and broken symmetry pp. 29-30

Claudio D. Stern

Crystallization of silicon ideas pp. 30-31

John Robertson

Stick it in the family album pp. 30-30

Chris Gunter

Enigmatic emission pp. 31-33

Takeshi Oka

Demand management in cells pp. 33-34

Stephen Oliver

Special treatment pp. 34-35

Giovanni Amelino-Camelia

Early land vertebrates pp. 35-36

Robert Carroll

Conserved function for embryonic nodal cilia pp. 37-38

Jeffrey J. Essner, Kyle J. Vogan, Molly K. Wagner, Clifford J. Tabin, H. Joseph Yost and Martina Brueckner

RNA interference in adult mice pp. 38-39

Anton P. McCaffrey, Leonard Meuse, Thu-Thao T. Pham, Douglas S. Conklin, Gregory J. Hannon and Mark A. Kay

Experimental quest for orbital waves pp. 39-40

M. Grüninger, R. Rückamp, M. Windt, P. Reutler, C. Zobel, T. Lorenz, A. Freimuth and A. Revcolevschi

Experimental quest for orbital waves pp. 40-40

E. Saitoh, S. Okamoto, K. Tobe, K. Yamamoto, T. Kimura, S. Ishihara, S. Maekawa and Y. Tokura

RETRACTED ARTICLE: Pluripotency of mesenchymal stem cells derived from adult marrow pp. 41-49

Yuehua Jiang, Balkrishna N. Jahagirdar, R. Lee Reinhardt, Robert E. Schwartz, C. Dirk Keene, Xilma R. Ortiz-Gonzalez, Morayma Reyes, Todd Lenvik, Troy Lund, Mark Blackstad, Jingbo Du, Sara Aldrich, Aaron Lisberg, Walter C. Low, David A. Largaespada and Catherine M. Verfaillie

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease pp. 50-56

Jong-Hoon Kim, Jonathan M. Auerbach, José A. Rodríguez-Gómez, Iván Velasco, Denise Gavin, Nadya Lumelsky, Sang-Hun Lee, John Nguyen, Rosario Sánchez-Pernaute, Krys Bankiewicz and Ron McKay

CO and H3+ in the protoplanetary disk around the star HD141569 pp. 57-59

Sean D. Brittain and Terrence W. Rettig

Interpretation of tomography and spectroscopy as dual forms of quantum computation pp. 59-62

César Miquel, Juan Pablo Paz, Marcos Saraceno, Emanuel Knill, Raymond Laflamme and Camille Negrevergne

Mechanism of hydrogen-induced crystallization of amorphous silicon pp. 62-65

Saravanapriyan Sriraman, Sumit Agarwal, Eray S. Aydil and Dimitrios Maroudas

Muted climate variations in continental Siberia during the mid-Pleistocene epoch pp. 65-68

Alexander A. Prokopenko, Douglas F. Williams, Mikhail I. Kuzmin, Eugene B. Karabanov, Galina K. Khursevich and John A. Peck

Mineralogy of the mid-ocean-ridge basalt source from neodymium isotopic composition of abyssal peridotites pp. 68-72

Vincent J. M. Salters and Henry J. B. Dick

An early tetrapod from ‘Romer's Gap’ pp. 72-76

J. A. Clack

A host–parasite interaction rescues Drosophila oogenesis defects pp. 76-79

Diana J. Starr and Thomas W. Cline

Sequence and analysis of chromosome 2 of Dictyostelium discoideum pp. 79-85

Gernot Glöckner, Ludwig Eichinger, Karol Szafranski, Justin A. Pachebat, Alan T. Bankier, Paul H. Dear, Rüdiger Lehmann, Cornelia Baumgart, Genís Parra, Josep F. Abril, Roderic Guigó, Kai Kumpf, Budi Tunggal, Edward Cox, Michael A. Quail, Matthias Platzer, André Rosenthal, Angelika A. Noegel, Bart G. Barrell, Marie-Adèle Rajandream, Jeffrey G. Williams, Robert R. Kay, Adam Kuspa, Richard Gibbs, Richard Sucgang, Donna Muzny, Brian Desany, Kathy Zeng, Baoli Zhu, Pieter de Jong, Theodor Dingermann, Günther Gerisch, Peter Philippsen, Michael Schleicher, Stephan C. Schuster and Thomas Winckler

Intracellular calcium stores regulate activity-dependent neuropeptide release from dendrites pp. 85-89

Mike Ludwig, Nancy Sabatier, Philip M. Bull, Rainer Landgraf, Govindan Dayanithi and Gareth Leng

Capacitance steps and fusion pores of small and large-dense-core vesicles in nerve terminals pp. 89-92

Vitaly A. Klyachko and Meyer B. Jackson

Dynamic interactions of cyclic AMP transients and spontaneous Ca2+ spikes pp. 93-96

Yuliya V. Gorbunova and Nicholas C. Spitzer

Determination of left–right patterning of the mouse embryo by artificial nodal flow pp. 96-99

Shigenori Nonaka, Hidetaka Shiratori, Yukio Saijoh and Hiroshi Hamada

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification pp. 99-104

Svend K. Petersen-Mahrt, Reuben S. Harris and Michael S. Neuberger

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast pp. 104-108

Zu-Wen Sun and C. David Allis

Correction: Corrigenda: BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes pp. 108-108

Philippe Bouillet, Jared F. Purton, Dale I. Godfrey, Li-Chen Zhang, Leigh Coultas, Hamsa Puthalakath, Marc Pellegrini, Suzanne Cory, Jerry M. Adams and Andreas Strasser

Correction: Corrigenda: Sudden aseismic fault slip on the south flank of Kilauea volcano pp. 108-108

Peter Cervelli, Paul Segall, Kaj Johnson, Michael Lisowski and Asta Miklius