Ageing nucleus gets out of shape
Hannes Lans and
Jan H. J. Hoeijmakers ()
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Hannes Lans: Erasmus Medical Center
Jan H. J. Hoeijmakers: Erasmus Medical Center
Nature, 2006, vol. 440, issue 7080, 32-34
Abstract:
In certain premature-ageing syndromes, the architecture of the cell nucleus is abnormal. An animal model shows similar malformations during normal ageing, corroborating the idea that genome instability underlies ageing.
Date: 2006
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DOI: 10.1038/440032a
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