Proton-coupled electron transfer drives the proton pump of cytochrome c oxidase

Ilya Belevich, Michael I. Verkhovsky and Mårten Wikström ()
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Ilya Belevich: University of Helsinki
Michael I. Verkhovsky: University of Helsinki
Mårten Wikström: University of Helsinki

Nature, 2006, vol. 440, issue 7085, 829-832

Abstract: Examining cytochrome c oxidase action shows that electron transfer from the haem group to the oxygen reduction site initiates the proton pumping mechanism — this occurs before relaxation steps, where protons are taken up from the aqueous space on one side of the membrane and released on the other.

Date: 2006
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DOI: 10.1038/nature04619

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