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2000, volume 406, articles 6799

Wellcome discusses structural genomics effort with industry… pp. 923-924

Declan Butler

…but data release remains an open question pp. 923-923

Declan Butler

Cambridge seeks £1.6 million to buy Newton's papers pp. 924-924

Natasha Loder

Novartis pins hopes for GM seeds on new marker system pp. 924-924

Quirin Schiermeier

Japan seeks science entrepreneurs pp. 925-926

David Cyranoski

Embryo stem-cell work gets NIH go-ahead pp. 925-925

Paul Smaglik

Ecologists back blueprint to save biodiversity hotspots pp. 926-926

Rex Dalton

North Carolina reflects on ammonia controls pp. 928-928

Jessa Netting

Chasing the dragons pp. 930-932

Rex Dalton

Sequencing solution: use volunteer annotators organized via Internet pp. 933-933

Fiona S. L. Brinkman, Robert E. W. Hancock and C. Kendal Stover

Let's get the right man in the right job pp. 933-933

David M. Wilkinson

Model already exists for fair use of gene data pp. 933-933

Andrew C. R. Martin

The tree of ignorance pp. 935-936

Robert W. Cahn

Martian chronicles pp. 936-937

Kenneth Nealson

Bad eggs pp. 937-938

Robert C. Fleischer

Time to deal with the legacy of secrecy pp. 938-938

Arthur C. Upton

The tube worm turns pp. 939-939

Roel Snieder

The flaw is human pp. 941-941

Jim Kling

Crystals that breathe pp. 943-944

Jonathan W. Steed

Sheep, lilies and human genetics pp. 944-945

Allen E. Bale

From robot dreams to reality pp. 945-947

Rodney Brooks

Pump up the versatility pp. 947-948

E. Peter Greenberg

The Lorenz attractor exists pp. 948-949

Ian Stewart

Channelling nutrients pp. 949-951

Kiaran Kirk

Probing the memory of mud pp. 951-952

Alan Kemp

Giving limbs a hand pp. 953-954

Martin J. Cohn

Power in the dust pp. 954-954

David Jones

Oceanic respite for wandering albatrosses pp. 955-956

Henri Weimerskirch and Rory P. Wilson

Caffeine synthase gene from tea leaves pp. 956-957

Misako Kato, Kouichi Mizuno, Alan Crozier, Tatsuhito Fujimura and Hiroshi Ashihara

Kainate receptors and synaptic plasticity pp. 957-957

R. A. Nicoll, J. Mellor, M. Frerking and D. Schmitz

reply: Kainate receptors and synaptic plasticity pp. 957-957

Zuner A. Bortolotto, Vernon R. J. Clarke, Caroline M. Delany, Michel Vignes and Graham L. Collingridge

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen pp. 959-964

C. K. Stover, X. Q. Pham, A. L. Erwin, S. D. Mizoguchi, P. Warrener, M. J. Hickey, F.S. L. Brinkman, W. O. Hufnagle, D. J. Kowalik, M. Lagrou, R. L. Garber, L. Goltry, E. Tolentino, S. Westbrock-Wadman, Y. Yuan, L. L. Brody, S. N. Coulter, K. R. Folger, A. Kas, K. Larbig, R. Lim, K. Smith, D. Spencer, G. K.-S. Wong, Z. Wu, I. T. Paulsen, J. Reizer, M. H. Saier, R. E. W. Hancock, S. Lory and M. V. Olson

Resonance as a measure of pairing correlations in the high-Tc superconductor YBa2Cu3O6.6 pp. 965-968

Pengcheng Dai, H. A. Mook, G. Aeppli, S. M. Hayden and F. Doğan

Quantum correlation among photons from a single quantum dot at room temperature pp. 968-970

P. Michler, A. Imamoğlu, M. D. Mason, P. J. Carson, G. F. Strouse and S. K. Buratto

Organoplatinum crystals for gas-triggered switches pp. 970-974

Martin Albrecht, Martin Lutz, Anthony L. Spek and Gerard van Koten

Automatic design and manufacture of robotic lifeforms pp. 974-978

Hod Lipson and Jordan B. Pollack

Acclimation of ecosystem CO2 exchange in the Alaskan Arctic in response to decadal climate warming pp. 978-981

Walter C. Oechel, George L. Vourlitis, Steven J. Hastings, Rommel C. Zulueta, Larry Hinzman and Douglas Kane

Diagenetic origin of quartz silt in mudstones and implications for silica cycling pp. 981-985

Jürgen Schieber, Dave Krinsley and Lee Riciputi

Density cycles and an offspring quantity and quality game driven by natural selection pp. 985-988

Barry Sinervo, Erik Svensson and Tosha Comendant

The role of microbes in accretion, lamination and early lithification of modern marine stromatolites pp. 989-992

R. P. Reid, P. T. Visscher, A. W. Decho, J. F. Stolz, B. M. Bebout, C. Dupraz, I. G. Macintyre, H. W. Paerl, J. L. Pinckney, L. Prufert-Bebout, T. F. Steppe and D. J. DesMarais

Ant-like task allocation and recruitment in cooperative robots pp. 992-995

Michael J. B. Krieger, Jean-Bernard Billeter and Laurent Keller

The relative metabolic demand of inhibition and excitation pp. 995-998

Daniel Waldvogel, Peter van Gelderen, Wolf Muellbacher, Ulf Ziemann, Ilka Immisch and Mark Hallett

A role for the C3a anaphylatoxin receptor in the effector phase of asthma pp. 998-1001

Alison A. Humbles, Bao Lu, Christy A. Nilsson, Craig Lilly, Elliot Israel, Yuko Fujiwara, Norma P. Gerard and Craig Gerard

A voltage-dependent channel involved in nutrient uptake by red blood cells infected with the malaria parasite pp. 1001-1005

Sanjay A. Desai, Sergey M. Bezrukov and Joshua Zimmerberg

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine pp. 1005-1009

Jussi Taipale, James K. Chen, Michael K. Cooper, Baolin Wang, Randall K. Mann, Ljiljana Milenkovic, Matthew P. Scott and Philip A. Beachy

The APC tumour suppressor has a nuclear export function pp. 1009-1012

Rina Rosin-Arbesfeld, Fiona Townsley and Mariann Bienz

Myosin V orientates the mitotic spindle in yeast pp. 1013-1015

Hongwei Yin, David Pruyne, Tim C. Huffaker and Anthony Bretscher

Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions pp. 1015-1019

Robert E. Johnson, M. Todd Washington, Lajos Haracska, Satya Prakash and Louise Prakash

The drive to miniaturization pp. 1023-1026

Paul S. Peercy

Pushing the limits of lithography pp. 1027-1031

Takashi Ito and Shinji Okazaki

Alternative dielectrics to silicon dioxide for memory and logic devices pp. 1032-1038

Angus I. Kingon, Jon-Paul Maria and S. K. Streiffer

Amplifying quantum signals with the single-electron transistor pp. 1039-1046

Michel H. Devoret and Robert J. Schoelkopf

Ultimate physical limits to computation pp. 1047-1054

Seth Lloyd

2000, volume 406, articles 6798

UK government backs change in law over stem-cell research… pp. 815-815

David Dickson and Paul Smaglik

… but Germany remains unmoved pp. 815-815

Quirin Schiermeier

Green Bank dish may be last of the giants pp. 816-816

Colin Macilwain

US regulation threat over business links… pp. 817-817

Paul Smaglik

…as government seeks more ethics training pp. 817-817

Paul Smaglik

US and Vietnam plan joint dioxin research pp. 818-818

Rex Dalton

Biodiversity cash aimed at hotspots pp. 818-818

Rex Dalton

Iceland's doctors rebuffed in health data row pp. 819-819

Alison Abbott

Astronomers reveal the secrets of the name game pp. 819-819

Steve Nadis

Databasing the brain pp. 822-825

Marina Chicurel

Industry benefits from the public funding of intellectual curiosity pp. 826-826

Paul Schimmel

When Brazilians achieve, it's against all the odds pp. 826-826

Tomas A. Prolla

The gift of Lepidoptera pp. 827-828

James Mallet

The bondage of symmetry broken pp. 828-829

David Blow

Expanding horizons pp. 829-830

Francesco Bertola

Science in culture pp. 830-830

Martin Kemp

The man who knew doses pp. 831-831

Rod Flower

Words, words, words pp. 833-833

Elisabeth Malartre

Vesicle fiesta at the synapse pp. 835-836

Gary Matthews

Another noble gas conquered pp. 836-837

Gernot Frenking

Directing direction pp. 839-840

R. A. Cross

Eat me! pp. 840-840

John Whitfield

Composite fermions pair up pp. 840-841

Nick Bonesteel

Frazzled precision guides axons pp. 841-843

Roman J. Giger and Alex L. Kolodkin

Tension in miniature pp. 843-843

David Jones

Elsie Widdowson (1906–2000) pp. 844-844

Margaret Ashwell

Navigation in a small world pp. 845-845

Jon M. Kleinberg

Nonlinearity and the Moran effect pp. 846-847

Bernd Blasius and Lewi Stone

reply: Nonlinearity and the Moran effect pp. 847-847

B. T. Grenfell, B. F. Finkenstädt, K. Wilson, T. N. Coulson and M.J. Crawley|

An actively controlled heart valve pp. 847-848

Craig E. Franklin and Michael Axelsson

Erratum: A triclosan-resistant bacterial enzyme pp. 848-848

Richard J. Heath and Charles O. Rock

Transport, capture and exocytosis of single synaptic vesicles at active zones pp. 849-854

D. Zenisek, J. A. Steyer and W. Almers

Structural and biochemical basis of apoptotic activation by Smac/DIABLO pp. 855-862

Jijie Chai, Chunying Du, Jia-Wei Wu, Saw Kyin, Xiaodong Wang and Yigong Shi

Cooper instability of composite fermions pp. 863-865

Vito W. Scarola, Kwon Park and J. K. Jain

Nitride semiconductors free of electrostatic fields for efficient white light-emitting diodes pp. 865-868

P. Waltereit, O. Brandt, A. Trampert, H. T. Grahn, J. Menniger, M. Ramsteiner, M. Reiche and K. H. Ploog

Liquid crystal phase transitions in suspensions of polydisperse plate-like particles pp. 868-871

Felix M. van der Kooij, Katerina Kassapidou and Henk N. W. Lekkerkerker

Multiscale modelling of plastic flow localization in irradiated materials pp. 871-874

Tomas Diaz de la Rubia, Hussein M. Zbib, Tariq A. Khraishi, Brian D. Wirth, Max Victoria and Maria Jose Caturla

A stable argon compound pp. 874-876

Leonid Khriachtchev, Mika Pettersson, Nino Runeberg, Jan Lundell and Markku Räsänen

Changes in Greenland ice sheet elevation attributed primarily to snow accumulation variability pp. 877-879

J. R. McConnell, R. J. Arthern, E. Mosley-Thompson, C. H. Davis, R. C. Bales, R. Thomas, J. F. Burkhart and J. D. Kyne

Evidence for iron, copper and zinc complexation as multinuclear sulphide clusters in oxic rivers pp. 879-882

Tim F. Rozan, Michael E. Lassman, Douglas P. Ridge and George W. Luther

Collapse and recovery of marine fishes pp. 882-885

Jeffrey A. Hutchings

The Drosophila Netrin receptor Frazzled guides axons by controlling Netrin distribution pp. 886-889

Masaki Hiramoto, Yasushi Hiromi, Edward Giniger and Yoshiki Hotta

Intracellular calcium dependence of transmitter release rates at a fast central synapse pp. 889-893

Ralf Schneggenburger and Erwin Neher

SLAM (CDw150) is a cellular receptor for measles virus pp. 893-897

Hironobu Tatsuo, Nobuyuki Ono, Kotaro Tanaka and Yusuke Yanagi

Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ pp. 897-902

Takehiko Sasaki, Junko Irie-Sasaki, Yasuo Horie, Kurt Bachmaier, Jimmie E. Fata, Martin Li, Akira Suzuki, Dennis Bouchard, Alexandra Ho, Mark Redston, Steven Gallinger, Rama Khokha, Tak W. Mak, Phillip T. Hawkins, Len Stephens, Stephen W. Scherer, Ming Tsao and Josef M. Penninger

Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice pp. 902-906

Yoshitaka Tanaka, Gundula Guhde, Anke Suter, Eeva-Liisa Eskelinen, Dieter Hartmann, Renate Lüllmann-Rauch, Paul M. L. Janssen, Judith Blanz, Kurt von Figura and Paul Saftig

Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease) pp. 906-910

Ichizo Nishino, Jin Fu, Kurenai Tanji, Takeshi Yamada, Sadatomo Shimojo, Tateo Koori, Marina Mora, Jack E. Riggs, Shin J. Oh, Yasutoshi Koga, Carolyn M. Sue, Ayaka Yamamoto, Nobuyuki Murakami, Sara Shanske, Edward Byrne, Eduardo Bonilla, Ikuya Nonaka, Salvatore DiMauro and Michio Hirano

JOINTLESS is a MADS-box gene controlling tomato flower abscissionzone development pp. 910-913

Long Mao, Dilara Begum, Huey-wen Chuang, Muhammad A. Budiman, Eugene J. Szymkowiak, Erin E. Irish and Rod A. Wing

A mutant of the motor protein kinesin that moves in both directions on microtubules pp. 913-916

Sharyn A. Endow and Hideo Higuchi

A deeply knotted protein structure and how it might fold pp. 916-919

William R. Taylor

2000, volume 406, articles 6797

Roslin backs off pig organ work pp. 663-663

Declan Butler

German scientists left in the cold as Berlin rejects rescue plan pp. 663-664

Alison Abbott and Ute Gitschel

Deal on reprints could mean royalties for scientists pp. 664-664

Rex Dalton

German government takes a narrow view of gene patents pp. 664-664

Quirin Schiermeier

Japan seeks to unify ethics rules on genomics research pp. 665-665

Robert Triendl

The sky's the limit as radio telescope array is approved pp. 665-666

Steve Nadis

NASA pins hopes on bigger, costlier mission to Mars pp. 666-666

William Triplett

Science champion joins US election race pp. 667-667

Colin Macilwain

Chemist tipped for top UK science post pp. 667-667

David Dickson

US dispute over definition of animal distress pp. 668-668

Jessica Netting

New fronts in an old war pp. 670-672

Declan Butler

Though HIV is the main cause of AIDS, other factors play a role pp. 673-673

R. T. D. Oliver

Responsible aquaculture can aid food problems pp. 673-673

M. J. Williams, J. D. Bell, M. V. Gupta, M. Dey, M. Ahmed, M. Prein, S. Child, P. R. Gardiner, R. Brummett and D. Jamu

Will we ever know what the Chinese knew? pp. 673-673

Ichikawa Shinji

Rights and wrongs pp. 675-676

Kenan Malik

Any old bones? pp. 676-677

Christopher Wills

From donkeys and cows to whales pp. 677-678

Axel Meyer

Science in culture pp. 678-678

Sara Abdulla

Powerful reactions pp. 679-679

Chauncey Starr

Worlds of IIF pp. 680-680

Roland Denison

Crop strength through diversity pp. 681-682

Martin S. Wolfe

Picture the smell pp. 682-683

Ingemar Lundström

Lipid lunch for persistent pathogen pp. 683-684

William Bishai

Feedback on Gaia pp. 685-686

Jim Gillon

The shaky trace pp. 686-687

Yadin Dudai

From insulator to superconductor pp. 687-688

Philip Phillips

Taking up iodide in breast tissue pp. 688-689

Piri L. Welcsh and David A. Mankoff

Ice sheets by volume pp. 689-690

Peter U. Clark and Alan C. Mix

Shuffling around pp. 690-690

David Jones

Attention is fast but volition is slow pp. 691-691

Jeremy M. Wolfe, George A. Alvarez and Todd S. Horowitz

A marine Wallace's line? pp. 692-693

Paul H. Barber, Stephen R. Palumbi, Mark V. Erdmann and M. Kasim Moosa

Neutron dose estimates from 5-yen coins pp. 693-693

Masuchika Kohno and Yoshinobu Koizumi

Atmospheric carbon dioxide concentrations over the past 60 million years pp. 695-699

Paul N. Pearson and Martin R. Palmer

Deep and stable interferometric nulling of broadband light with implications for observing planets around nearby stars pp. 700-702

Kent Wallace, Graham Hardy and Eugene Serabyn

RETRACTED ARTICLE: Superconductivity in molecular crystals induced by charge injection pp. 702-704

J. H. Schön, Ch. Kloc and B. Batlogg

Room-temperature electronic phase transitions in the continuous phase diagrams of perovskite manganites pp. 704-708

Young-Kook Yoo, Fred Duewer, Haitao Yang, Dong Yi, Jing-Wei Li and X.-D. Xiang

Stress transmission through a model system of cohesionless elastic grains pp. 708-710

Miguel Da Silva and Jean Rajchenbach

A colorimetric sensor array for odour visualization pp. 710-713

Neal A. Rakow and Kenneth S. Suslick

Timing of the Last Glacial Maximum from observed sea-level minima pp. 713-716

Yusuke Yokoyama, Kurt Lambeck, Patrick De Deckker, Paul Johnston and L. Keith Fifield

Cursoriality in bipedal archosaurs pp. 716-718

Terry D. Jones, James O. Farlow, John A. Ruben, Donald M. Henderson and Willem J. Hillenius

Genetic diversity and disease control in rice pp. 718-722

Youyong Zhu, Hairu Chen, Jinghua Fan, Yunyue Wang, Yan Li, Jianbing Chen, JinXiang Fan, Shisheng Yang, Lingping Hu, Hei Leung, Tom W. Mew, Paul S. Teng, Zonghua Wang and Christopher C. Mundt

Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval pp. 722-726

Karim Nader, Glenn E. Schafe and Joseph E. Le Doux

Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex pp. 726-731

Takuji Iwasato, Akash Datwani, Alexander M. Wolf, Hiroshi Nishiyama, Yusuke Taguchi, Susumu Tonegawa, Thomas Knöpfel, Reha S. Erzurumlu and Shigeyoshi Itohara

Calcium channels activated by hydrogen peroxide mediate abscisic acid signalling in guard cells pp. 731-734

Zhen-Ming Pei, Yoshiyuki Murata, Gregor Benning, Sébastien Thomine, Birgit Klüsener, Gethyn J. Allen, Erwin Grill and Julian I. Schroeder

Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase pp. 735-738

John D. McKinney, Kerstin Höner zu Bentrup, Ernesto J. Muñoz-Elías, Andras Miczak, Bing Chen, Wai-Tsing Chan, Dana Swenson, James C. Sacchettini, William R. Jacobs and David G. Russell

Progression of autoimmune diabetes driven by avidity maturation of a T-cell population pp. 739-742

Abdelaziz Amrani, Joan Verdaguer, Pau Serra, Sabrina Tafuro, Rusung Tan and Pere Santamaria

The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells pp. 742-747

Peter J. P. Coopman, Michael T. H. Do, Mara Barth, Emma T. Bowden, Andrew J. Hayes, Eugenia Basyuk, Jan K. Blancato, Phyllis R. Vezza, Sandra W. McLeskey, Paul H. Mangeat and Susette C. Mueller

Molecular portraits of human breast tumours pp. 747-752

Charles M. Perou, Therese Sørlie, Michael B. Eisen, Matt van de Rijn, Stefanie S. Jeffrey, Christian A. Rees, Jonathan R. Pollack, Douglas T. Ross, Hilde Johnsen, Lars A. Akslen, Øystein Fluge, Alexander Pergamenschikov, Cheryl Williams, Shirley X. Zhu, Per E. Lønning, Anne-Lise Børresen-Dale, Patrick O. Brown and David Botstein

Potential for biomolecular imaging with femtosecond X-ray pulses pp. 752-757

Richard Neutze, Remco Wouts, David van der Spoel, Edgar Weckert and Janos Hajdu

On the particularity of pathogens pp. 760-761

Barry R. Bloom

Changing patterns of infectious disease pp. 762-767

Mitchell L. Cohen

Pathogenic strategies of enteric bacteria pp. 768-774

Michael S. Donnenberg

Molecular mechanisms that confer antibacterial drug resistance pp. 775-781

Christopher Walsh

Toll-like receptors in the induction of the innate immune response pp. 782-787

Alan Aderem and Richard J. Ulevitch

CD1-restricted T-cell responses and microbial infection pp. 788-792

Se-Ho Park and Albert Bendelac

Vaccines against intracellular infections requiring cellular immunity pp. 793-798

Robert A. Seder and Adrian V. S. Hill

Microbial genome sequencing pp. 799-803

Claire M. Fraser, Jonathan A. Eisen and Steven L. Salzberg

Basic Science, Clinical Development, Global Surveillance pp. 804-804

Peter S. Ringrose

‘Quiet revolution’ in chemistry could revive public and private sectors pp. 807-808

Paul Smaglik

European industry turns to the academics to secure its future pp. 809-811

Helen Gavaghan

Undergraduate interest in chemistry wanes in Europe pp. 809-809

Helen Gavaghan

Emerging fields of basic chemistry in Europe pp. 811-812

Helen Gavaghan

Mergers and acquisitions rock UK chemical industry infrastructure pp. 812-812

Helen Gavaghan

US companies seek basic science pp. 812-812

Paul Smaglik

2000, volume 406, articles 6796

United States backs soil strategy in fight against global warming pp. 549-550

Paul Smaglik

Royalty-free rice arrives on the web pp. 549-549

David Dickson

Spanish biomedical centres face funding uncertainty pp. 550-550

Xavier Bosch

Strong sterling hits European researchers pp. 551-551

Natasha Loder

Microsoft moguls back search for ET intelligence pp. 551-551

Rex Dalton

From cell phones to brain cells pp. 552-552

Rex Dalton

Kansas scientists help to oust creationists pp. 552-553

Rex Dalton

Internet is the new key for restructured film institute pp. 553-553

Quirin Schiermeier

German scientists pledge to fight growing xenophobia pp. 553-553

Quirin Schiermeier and Ute Gitschel

Through the looking glass pp. 556-558

Alexander Hellemans

A mutant mouse menagerie pp. 559-559

Alison Abbott

Hawaiian legal action can't save leatherbacks: tackle driftnets instead pp. 560-560

John LaGrange

Wise fool left Hussars for career in science admin pp. 560-560

Dmitry Zharkov

Environment regulations hinder biotech industry pp. 560-560

Henry I. Miller

Blessed with more than avoirdupois pp. 561-562

Andrew Berry

Venusian visitation pp. 562-562

Don Fernie

From trenches to couches pp. 563-564

John Galloway

Paragon lost pp. 564-564

Michael Baumann

Boundary disputes pp. 565-565

Jonathan C. Horton

An end to violence pp. 567-567

Roger Smith

Bacteriorhodopsin — the movie pp. 569-570

Werner Kühlbrandt

Electrons in a strange sea pp. 571-573

Patricia A. Thiel and Jean Marie Dubois

Benefits of bad telomeres pp. 573-574

Douglas Hanahan

The giant diatom dump pp. 574-575

Victor Smetacek

Making membranes in bacteria pp. 575-577

Rosemary A. Stuart and Walter Neupert

Portrait of a magma chamber pp. 578-579

Robert S. Detrick

Formatting genetic text pp. 579-580

Renato Paro

On the verge of magnetism pp. 580-581

Piers Coleman

Erratum: On the verge of magnetism pp. 581-581

Satish K. Nair and Stephen K. Burley

Spinning and leaking pp. 581-581

David Jones

W. David Kingery (1926–2000) pp. 582-582

Richard J. Brook

Predicted vCJD mortality in Great Britain pp. 583-584

Azra C. Ghani, Neil M. Ferguson, Christl A. Donnelly and Roy M. Anderson

Scrapie in Britain during the BSE years pp. 584-585

Mike B. Gravenor, D. R. Cox, Linda J. Hoinville, Alies Hoek and Angela R. McLean

Exercise and reduced muscle mass in starlings pp. 585-586

John P. Swaddle and Andrew A. Biewener

Peeling and sharpening multiwall nanotubes pp. 586-586

John Cumings, Philip G. Collins and A. Zettl

Superconductivity on the border of itinerant-electron ferromagnetism in UGe2 pp. 587-592

S. S. Saxena, P. Agarwal, K. Ahilan, F. M. Grosche, R. K. W. Haselwimmer, M. J. Steiner, E. Pugh, I. R. Walker, S. R. Julian, P. Monthoux, G. G. Lonzarich, A. Huxley, I. Sheikin, D. Braithwaite and J. Flouquet

Regulation of chromatin structure by site-specific histone H3 methyltransferases pp. 593-599

Stephen Rea, Frank Eisenhaber, Dónal O'Carroll, Brian D. Strahl, Zu-Wen Sun, Manfred Schmid, Susanne Opravil, Karl Mechtler, Chris P. Ponting, C. David Allis and Thomas Jenuwein

Evaporation in the young solar nebula as the origin of ‘just-right’ melting of chondrules pp. 600-602

Bosmat A. Cohen, Roger H. Hewins and Yang Yu

Quasicrystalline valence bands in decagonal AlNiCo pp. 602-605

Eli Rotenberg, W. Theis, K. Horn and P. Gille

A DNA-fuelled molecular machine made of DNA pp. 605-608

Bernard Yurke, Andrew J. Turberfield, Allen P. Mills, Friedrich C. Simmel and Jennifer L. Neumann

Influencing intramolecular motion with an alternating electric field pp. 608-611

Veronica Bermudez, Nathalie Capron, Torsten Gase, Francesco G. Gatti, François Kajzar, David A. Leigh, Francesco Zerbetto and Songwei Zhang

Water activity as the determinant for homogeneous ice nucleation in aqueous solutions pp. 611-614

Thomas Koop, Beiping Luo, Athanasios Tsias and Thomas Peter

Evidence from three-dimensional seismic reflectivity images for enhanced melt supply beneath mid-ocean -ridge discontinuities pp. 614-618

G. M. Kent, S. C. Singh, A. J. Harding, M. C. Sinha, J. A. Orcutt, P. J. Barton, R. S. White, S. Bazin, R. W. Hobbs, C. H. Tong and J. W. Pye

Fine structure of bone in dinosaurs, birds and mammals pp. 619-622

John M. Rensberger and Mahito Watabe

Unexpectedly similar rates of nucleotide substitution found in male and female hominids pp. 622-625

Hacho B. Bohossian, Helen Skaletsky and David C. Page

Evolvability of an RNA virus is determined by its mutational neighbourhood pp. 625-628

Christina L. Burch and Lin Chao

Behaviourally driven gene expression reveals song nuclei in hummingbird brain pp. 628-632

Erich D. Jarvis, Sidarta Ribeiro, Maria Luisa da Silva, Dora Ventura, Jacques Vielliard and Claudio V. Mello

NO is necessary and sufficient for egg activation at fertilization pp. 633-636

Richard C. Kuo, Gregory T. Baxter, Stuart H. Thompson, Stephen A. Stricker, Chris Patton, Joseph Bonaventura and David Epel

YidC mediates membrane protein insertion in bacteria pp. 637-641

James C. Samuelson, Minyong Chen, Fenglei Jiang, Ines Möller, Martin Wiedmann, Andreas Kuhn, Gregory J. Phillips and Ross E. Dalbey

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice pp. 641-645

Steven E. Artandi, Sandy Chang, Shwu-Luan Lee, Scott Alson, Geoffrey J. Gottlieb, Lynda Chin and Ronald A. DePinho

Helix deformation is coupled to vectorial proton transport in the photocycle of bacteriorhodopsin pp. 645-648

Antoine Royant, Karl Edman, Thomas Ursby, Eva Pebay-Peyroula, Ehud M. Landau and Richard Neutze

Structural alterations for proton translocation in the M state of wild-type bacteriorhodopsin pp. 649-653

Hans Jürgen Sass, Georg Büldt, Ralf Gessenich, Dominic Hehn, Dirk Neff, Ramona Schlesinger, Joel Berendzen and Pal Ormos

Molecular mechanism of vectorial proton translocation by bacteriorhodopsin pp. 653-657

Sriram Subramaniam and Richard Henderson

2000, volume 406, articles 6795

UK hopes that big-money deals will attract top talent pp. 446-446

Natasha Loder

Science may lose out from sale of ‘flying reptile’ fossil pp. 446-446

Jessa Netting

Researchers criticize response to killer algae pp. 447-447

Rex Dalton

France may bid for fusion reactor pp. 447-447

Heather McCabe

Astronomers silenced in star-name wars pp. 448-448

William Triplett

Berlin genome centre to go ahead pp. 448-448

Quirin Schiermeier

Ocean researchers dive to deep-sea stations pp. 449-449

Colin Macilwain

Ecology goes underground pp. 452-454

Jon Copley

How can the developing world protect itself from biotech patent-holders? pp. 455-455

John H. Barton and Joseph Strauss

Cost of institute was small change to Roche pp. 455-455

Urs Christen

How neptunium led to the birth of plutonium pp. 455-455

C. R. Richmond

The road to decarbonized energy pp. 457-458

Stanford R. Ovshinsky

Forces to be reckoned with pp. 458-458

Peter Wrobel

Romancing the dome pp. 458-459

Rodney Cotterill

Trek to an inhabited wilderness pp. 459-460

Louis Warren

Science in culture pp. 460-460

Haim Watzman

Start making sense pp. 461-461

Raúl Camba

Taking control pp. 462-462

Gregory Benford

Biodiversity's ups and downs pp. 463-464

Peter J. Morin

Catching crystals at birth pp. 464-465

David W. Oxtoby

Plaque removers and shakers pp. 465-465

Marie-Thérèse Heemels

Molecular switches in metastasis pp. 466-467

Anne Ridley

Some vortices like it hot pp. 467-468

Patrick A. Lee

Iron uncertainty pp. 468-469

Adina Paytan

Treasure trove for cholera research pp. 469-470

Matthew K. Waldor and Debabrata RayChaudhuri

Taking the Earth's temperature pp. 470-471

Ian Jackson

The soda solution pp. 471-471

David Jones

Seymour S. Kety (1915–2000) pp. 472-472

Leon Elsenberg

Oncogene inactivation in a mouse model pp. 473-474

Tsuyoshi Tanabe, Tomoko Kuwabara, Masaki Warashina, Kenzaburo Tani, Kazunari Taira and Shigetaka Asano

Home-site fidelity in migratory honeybees pp. 474-475

Peter Neumann, Nikolaus Koeniger, Gudrun Koeniger, Salim Tingek, Per Kryger and Robin F. A. Moritz

Giant honeybees return to their nest sites pp. 475-475

J. Paar, B. P. Oldroyd and G. Kastberger

DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae pp. 477-483

John F. Heidelberg, Jonathan A. Eisen, William C. Nelson, Rebecca A. Clayton, Michelle L. Gwinn, Robert J. Dodson, Daniel H. Haft, Erin K. Hickey, Jeremy D. Peterson, Lowell Umayam, Steven R. Gill, Karen E. Nelson, Timothy D. Read, Hervé Tettelin, Delwood Richardson, Maria D. Ermolaeva, Jessica Vamathevan, Steven Bass, Haiying Qin, Ioana Dragoi, Patrick Sellers, Lisa McDonald, Teresa Utterback, Robert D. Fleishmann, William C. Nierman, Owen White, Steven L. Salzberg, Hamilton O. Smith, Rita R. Colwell, John J. Mekalanos, J. Craig Venter and Claire M. Fraser

Evidence for free precession in a pulsar pp. 484-486

I. H. Stairs, A. G. Lyne and S. L. Shemar

Vortex-like excitations and the onset of superconducting phase fluctuation in underdoped La2-xSrxCuO4 pp. 486-488

Z. A. Xu, N. P. Ong, Y. Wang, T. Kakeshita and S. Uchida

Pixel switching of epitaxial Pd/YHx/CaF2 switchable mirrors pp. 489-491

J. W. J. Kerssemakers, S. J. van der Molen, N. J. Koeman, R. Günther and R. Griessen

Electrostatic trapping of ammonia molecules pp. 491-494

Hendrick L. Bethlem, Giel Berden, Floris M. H. Crompvoets, Rienk T. Jongma, André J. A. van Roij and Gerard Meijer

Quasi-planar nucleus structure in apoferritin crystallization pp. 494-497

S.-T. Yau and Peter G. Vekilov

Marine control of biological production in the eastern equatorial Pacific Ocean pp. 497-500

Paul Loubere

Annual modulation of triggered seismicity following the 1992 Landers earthquake in California pp. 500-504

Stephen S. Gao, Paul G. Silver, Alan T. Linde and I. Selwyn Sacks

Ocean circulation off east Antarctica affects ecosystem structure and sea-ice extent pp. 504-507

Stephen Nicol, Tim Pauly, Nathan L. Bindoff, Simon Wright, Deborah Thiele, Graham W. Hosie, Peter G. Strutton and Eric Woehler

Diversity peaks at intermediate productivity in a laboratory microcosm pp. 508-512

Rees Kassen, Angus Buckling, Graham Bell and Paul B. Rainey

Herbivory-induced volatiles elicit defence genes in lima bean leaves pp. 512-515

Gen-ichiro Arimura, Rika Ozawa, Takeshi Shimoda, Takaaki Nishioka, Wilhelm Boland and Junji Takabayashi

Genetic and epigenetic mechanisms contribute to motor neuron pathfinding pp. 515-519

Kamal Sharma, Ann E. Leonard, Karen Lettieri and Samuel L. Pfaff

An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells pp. 519-524

David Whyatt, Fokke Lindeboom, Alar Karis, Rita Ferreira, Eric Milot, Rudi Hendriks, Marella de Bruijn, An Langeveld, Joost Gribnau, Frank Grosveld and Sjaak Philipsen

Different initiation of pre-TCR and γδTCR signalling pp. 524-527

Claude Saint-Ruf, Maddalena Panigada, Orly Azogui, Pascale Debey, Harald von Boehmer and Fabio Grassi

Distinct β-catenins mediate adhesion and signalling functions in C. elegans pp. 527-532

Hendrik C. Korswagen, Michael A. Herman and Hans C. Clevers

Genomic analysis of metastasis reveals an essential role for RhoC pp. 532-535

Edwin A. Clark, Todd R. Golub, Eric S. Lander and Richard O. Hynes

Molecular classification of cutaneous malignant melanoma by gene expression profiling pp. 536-540

M. Bittner, P. Meltzer, Y. Chen, Y. Jiang, E. Seftor, M. Hendrix, M. Radmacher, R. Simon, Z. Yakhini, A. Ben-Dor, N. Sampas, E. Dougherty, E. Wang, F. Marincola, C. Gooden, J. Lueders, A. Glatfelter, P. Pollock, J. Carpten, E. Gillanders, D. Leja, K. Dietrich, Catherine Beaudry, M. Berens, D. Alberts, V. Sondak, N. Hayward and J. Trent

A chromatin remodelling complex involved in transcription and DNA processing pp. 541-544

Xuetong Shen, Gaku Mizuguchi, Ali Hamiche and Carl Wu

Collaborations prepare to untangle the circuitry of the brain pp. 545-546

Diane Gershon

Mahoney centre set to tackle brain cancer head on pp. 546-546

Diane Gershon

2000, volume 406, articles 6794

Emissions targets ‘unrealistic’ says US climate change body pp. 333-333

Colin Macilwain

Ensembl gets a Wellcome boost pp. 333-333

Declan Butler

Physicists celebrate detection of elusive ‘final’ particle pp. 334-334

Colin Macilwain

Proposal for US patent office could help cut waiting time pp. 334-334

Paul Smaglik

Summit leaders fail to bridge GM food split pp. 335-335

David Dickson

UK science plans spending spree pp. 335-335

Natasha Loder

Legal protests prompt DNA primer release pp. 336-336

Paul Smaglik

Review panel assails Brussels research bureaucracy pp. 336-336

Quirin Schiermeier

Call for North/South code of research ethics pp. 337-337

Declan Butler

Manhattan versus Reykjavik pp. 340-342

Alison Abbott

How new technology put a coelacanth among the heirs of Piltdown Man pp. 343-343

M. V. Erdmann and R. L. Caldwell

Assessors' odd listings don't inspire confidence pp. 343-343

Miguel A. García-Pérez

Reductionism should be clarified, not dismissed pp. 343-343

J. R. S. Fincham

Pitching it right pp. 345-346

Alison Jolly

The spice of life pp. 346-347

Pat Willmer

Tangled strands in the double helix pp. 347-348

Mark Ridley

Story of a favourite mathematical tool pp. 348-348

Jeremy Gray

What if…? pp. 349-349

John Carmody

The bottle pp. 351-351

Tom D. Schneider

How robust is the Internet? pp. 353-354

Yuhai Tu

Conducting the mitotic symphony pp. 354-356

David Cortez and Stephen J. Elledge

Deciphering methane's fingerprint pp. 356-357

Helmut Weissert

Fringe benefits to carbohydrates pp. 357-358

Mark E. Fortini

Silica control of carbon dioxide pp. 358-359

Paul Tréguer and Philippe Pondaven

The extraterrestrial wedding ring pp. 359-360

Richard J. Walker

Hidden thoughts pp. 360-360

David Jones

Stem cells — hype and hope pp. 361-364

Ron McKay

Five plus two equals yellow pp. 365-365

Mike J. Dixon, Daniel Smilek, Cera Cudahy and Philip M. Merikle

Climate change and constraints on breeding pp. 366-367

Ian R. Stevenson and David M. Bryant

Kinase regulation in inflammatory response pp. 367-368

Mireille Delhase, Nanxin Li and Michael Karin

reply: Kinase regulation in inflammatory response pp. 368-368

Osman Nidai Ozes, Lindsey D. Mayo, Jason A. Gustin, Susan R. Pfeffer, Lawrence M. Pfeffer and David B. Donner

Correction: Energy for microbial life on Europa pp. 368-368

C. Chyba

Erratum: Do cockroaches ‘know’ about fluid dynamics? pp. 368-368

D. Rinberg and H. Davidowitz

Fringe is a glycosyltransferase that modifies Notch pp. 369-375

Daniel J. Moloney, Vladislav M. Panin, Stuart H. Johnston, Jihua Chen, Li Shao, Richa Wilson, Yang Wang, Pamela Stanley, Kenneth D. Irvine, Robert S. Haltiwanger and Thomas F. Vogt

Characterizing the nonlinear growth of large-scale structure in the Universe pp. 376-378

Peter Coles and Lung-Yih Chiang

Error and attack tolerance of complex networks pp. 378-382

Réka Albert, Hawoong Jeong and Albert-László Barabási

Controlled surface charging as a depth-profiling probe for mesoscopic layers pp. 382-385

Ilanit Doron-Mor, Anat Hatzor, Alexander Vaskevich, Tamar van der Boom-Moav, Abraham Shanzer, Israel Rubinstein and Hagai Cohen

Signatures of granular microstructure in dense shear flows pp. 385-389

Daniel M. Mueth, Georges F. Debregeas, Greg S. Karczmar, Peter J. Eng, Sidney R. Nagel and Heinrich M. Jaeger

Oscillatory cluster patterns in a homogeneous chemical system with global feedback pp. 389-391

Vladimir K. Vanag, Lingfa Yang, Milos Dolnik, Anatol M. Zhabotinsky and Irving R. Epstein

Massive dissociation of gas hydrate during a Jurassic oceanic anoxic event pp. 392-395

Stephen P. Hesselbo, Darren R. Gröcke, Hugh C. Jenkyns, Christian J. Bjerrum, Paul Farrimond, Helen S. Morgans Bell and Owen R. Green

Evidence for a late chondritic veneer in the Earth's mantle from high-pressure partitioning of palladium and platinum pp. 396-399

A. Holzheid, P. Sylvester, H. St C. O'Neill, D. C. Rubie and H. Palme

Mutation and sex in a competitive world pp. 399-404

Joel R. Peck and David Waxman

Long-term vocal recognition in the northern fur seal pp. 404-405

Stephen J. Insley

State-dependent cross-inhibition between transmitter-gated cation channels pp. 405-410

Baljit S. Khakh, Xiaoping Zhou, Jason Sydes, James J. Galligan and Henry A. Lester

Glycosyltransferase activity of Fringe modulates Notch–Delta interactions pp. 411-415

Katja Brückner, Lidia Perez, Henrik Clausen and Stephen Cohen

Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean pp. 415-418

John C. Clapham, Jonathan R. S. Arch, Helen Chapman, Andrea Haynes, Carolyn Lister, Gary B. T. Moore, Valerie Piercy, Sabrina A. Carter, Ines Lehner, Stephen A. Smith, Lee J. Beeley, Robert J. Godden, Nicole Herrity, Mark Skehel, K. Kumar Changani, Paul D. Hockings, David G. Reid, Sarah M. Squires, Jonathan Hatcher, Brenda Trail, Judy Latcham, Sohaila Rastan, Alexander J. Harper, Susana Cadenas, Julie A. Buckingham, Martin D. Brand and Alejandro Abuin

GATA3 haplo-insufficiency causes human HDR syndrome pp. 419-422

Hilde Van Esch, Peter Groenen, M. Andrew Nesbit, Simone Schuffenhauer, Peter Lichtner, Gert Vanderlinden, Brian Harding, Rolf Beetz, Rudolf W. Bilous, Ian Holdaway, Nicholas J. Shaw, Jean-Pierre Fryns, Wim Van de Ven, Rajesh V. Thakker and Koenraad Devriendt

A motif in the αβ T-cell receptor controls positive selection by modulating ERK activity pp. 422-426

Guy Werlen, Barbara Hausmann and Ed Palmer

CD3δ couples T-cell receptor signalling to ERK activation and thymocyte positive selection pp. 426-430

Pilar Delgado, Edgar Fernández, Vibhuti Dave, Dietmar Kappes and Balbino Alarcón

Chfr defines a mitotic stress checkpoint that delays entry into metaphase pp. 430-435

Daniel M. Scolnick and Thanos D. Halazonetis

Humanized xenobiotic response in mice expressing nuclear receptor SXR pp. 435-439

Wen Xie, Joyce L. Barwick, Michael Downes, Bruce Blumberg, Cynthia M. Simon, Michael C. Nelson, Brent A. Neuschwander-Tetri, Elizabeth M. Brunt, Philip S. Guzelian and Ronald M. Evans

Correction: The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338 pp. 439-439

Alastair J. King, Hualya Sun, Bruce Diaz, Darlene Bernard, Wenyan Miao, Shubha Bagrodia and Mark S. Marshall

Erratum: Turbulent convection at very high Rayleigh numbers pp. 439-439

J. J. Niemela, L. Skrbek, K. R. Sreenivasan and R. J. Donnelly

2000, volume 406, articles 6793

Jordan chosen to open SESAME pp. 221-221

Heather McCabe

Large research facilities to lose out in science spending spree? pp. 221-222

Colin Macilwain

UK space strategy slammed as lacking funds and vision pp. 222-222

Natasha Loder

Cluster leaves the ground — at last pp. 222-222

Natasha Loder

Diplomatic Mandela calls for action on HIV… pp. 223-223

Michael Cherry

…as South Africa considers its options after free drugs offer pp. 223-223

Michael Cherry

Diabetes therapy boosts stem-cell campaign pp. 224-224

Paul Smaglik

Industry considers carbon catching pp. 224-224

Steve Nadis

Enhanced advisory role urged for former EU nuclear labs pp. 225-225

Quirin Schiermeier

Brown boosts British science base pp. 225-225

Natasha Loder

Recriminations and confusion over ‘fake’ coelacanth photo pp. 225-225

Heather McCabe

Anti-smoking critic wins campaigning right pp. 226-226

Rex Dalton

German librarians cautious of brave new digital world pp. 227-227

Quirin Schiermeier

Bones, molecules…or both? pp. 230-233

Trisha Gura

Caution is sensible, but give biotech a chance to show the good it can do pp. 234-234

Enrico Porceddu

A fault in the ‘weak San Andreas’ theory pp. 234-234

C. H. Scholz

That famous double helix takes a sinister turn pp. 234-234

Colin Porter

The biotechnologist's jungle book pp. 235-236

Walter Gratzer

A function for dysfunction pp. 236-237

Thomas J. Jentsch

Conservation gets heavy pp. 237-238

Rory Howlett

Chemistry's Canterbury Tales pp. 238-238

John Emsley

Jumbo pp. 239-239

Vaclav Smil

All is not lost pp. 241-241

Scott Westerfeld

Faster than a speeding photon pp. 243-244

Jon Marangos

Science in motion pp. 244-245

Philip Ball

Parallel sensing pp. 245-247

Mathew E. Diamond

Enlightening water vapour pp. 247-248

Brian J. Soden

Fair game pp. 248-249

Ruth Mace

Adding to the antifreeze agenda pp. 249-251

Charles A. Knight

Best packing in proteins and DNA pp. 251-252

Andrzej Stasiak and John H. Maddocks

A protein accumulator pp. 253-254

Jennifer C. Pinder and Anthony J. Baines

Pulses of the mind pp. 254-254

David Jones

Spider manipulation by a wasp larva pp. 255-256

William G. Eberhard

Heat-stable antifreeze protein from grass pp. 256-256

Chris Sidebottom, Sarah Buckley, Paul Pudney, Sarah Twigg, Carl Jarman, Chris Holt, Julia Telford, Andrew McArthur, Dawn Worrall, Rod Hubbard and Peter Lillford

Hepatocytes from non-hepatic adult stem cells pp. 257-257

Malcolm R. Alison, Richard Poulsom, Rosemary Jeffery, Amar P. Dhillon, Alberto Quaglia, Joe Jacob, Marco Novelli, Grant Prentice, Jill Williamson and Nicholas A. Wright

Structure of the Fc fragment of human IgE bound to its high-affinity receptor FcεRIα pp. 259-266

Scott C. Garman, Beth A. Wurzburg, Svetlana S. Tarchevskaya, Jean-Pierre Kinet and Theodore S. Jardetzky

The 3.2-Å crystal structure of the human IgG1 Fc fragment–FcγRIII complex pp. 267-273

Peter Sondermann, Robert Huber, Vaughan Oosthuizen and Uwe Jacob

Determining the ages of comets from the fraction of crystalline dust pp. 275-276

Joseph A. Nuth, Hugh G. M. Hill and Gunther Kletetschka

Gain-assisted superluminal light propagation pp. 277-279

L. J. Wang, A. Kuzmich and A. Dogariu

Non-collinear states in magnetic sensors pp. 280-282

Adrian Taga, Lars Nordström, Peter James, Börje Johansson and Olle Eriksson

Imaging the vortex-lattice melting process in the presence of disorder pp. 282-287

Alex Soibel, Eli Zeldov, Michael Rappaport, Yuri Myasoedov, Tsuyoshi Tamegai, Shuuichi Ooi, Marcin Konczykowski and Vadim B. Geshkenbein

Optimal shapes of compact strings pp. 287-290

Amos Maritan, Cristian Micheletti, Antonio Trovato and Jayanth R. Banavar

Evidence for a link between global lightning activity and upper tropospheric water vapour pp. 290-293

Colin Price

Melting of the Earth's lithospheric mantle inferred from protactinium– thorium–uranium isotopic data pp. 293-296

Yemane Asmerom, Hai Cheng, Rebecca Thomas, Marc Hirschmann and R. Lawrence Edwards

Female bluethroats enhance offspring immunocompetence through extra-pair copulations pp. 296-299

Arild Johnsen, Vegard Andersen, Christine Sunding and Jan T. Lifjeld

Magnetite defines a vertebrate magnetoreceptor pp. 299-302

Carol E. Diebel, Roger Proksch, Colin R. Green, Peter Neilson and Michael M. Walker

Transformation from temporal to rate coding in a somatosensory thalamocortical pathway pp. 302-306

Ehud Ahissar, Ronen Sosnik and Sebastian Haidarliu

Presenilin is required for proper morphology and function of neurons in C. elegans pp. 306-309

Nicole Wittenburg, Stefan Eimer, Bernard Lakowski, Sascha Röhrig, Claudia Rudolph and Ralf Baumeister

A chemokine-driven positive feedback loop organizes lymphoid follicles pp. 309-314

K. Mark Ansel, Vu N. Ngo, Paul L. Hyman, Sanjiv A. Luther, Reinhold Förster, Jonathon D. Sedgwick, Jeffrey L. Browning, Martin Lipp and Jason G. Cyster

A tertiary interaction that links active-site domains to the 5′ splice site of a group II intron pp. 315-318

Marc Boudvillain, Alexandre de Lencastre and Anna Marie Pyle

A ratchet-like inter-subunit reorganization of the ribosome during translocation pp. 318-322

Joachim Frank and Rajendra Kumar Agrawal

Mimicry of ice structure by surface hydroxyls and water of a β-helix antifreeze protein pp. 322-324

Yih-Cherng Liou, Ante Tocilj, Peter L. Davies and Zongchao Jia

β-Helix structure and ice-binding properties of a hyperactive antifreeze protein from an insect pp. 325-328

Steffen P. Graether, Michael J. Kuiper, Stéphane M. Gagné, Virginia K. Walker, Zongchao Jia, Brian D. Sykes and Peter L. Davies

2000, volume 406, articles 6792

German agencies sound alarm on risks of broad gene patents… pp. 111-111

Quirin Schiermeier

…as spending goes up for research pp. 111-111

Quirin Schiermeier

Internet publishing camps renew hostilities pp. 112-112

Colin Macilwain

US scientists seek more funds for high-tech equipment pp. 112-112

Paul Smaglik

Mbeki gives AIDS scientists the cold shoulder pp. 113-113

Michael Cherry

UK studentships get funding boost pp. 113-114

Natasha Loder

Tangled tale of a lost, stolen and disputed coelacanth pp. 114-114

Heather McCabe and Janet Wright

Sweden streamlines research administration pp. 115-115

Declan Butler

Scientists back GM for Third World pp. 115-115

David Dickson

Chemistry meets computing pp. 118-120

Philip Ball

Landsat reveals China's farmland reserves, but they're vanishing fast pp. 121-121

Karen C. Seto, Robert Kaufmann and Curtis E. Woodcock

Please don't downgrade the sequencers' role … pp. 121-122

Michael Gottlieb, Victoria McGovern, Patricia Goodwin, Stephen Hoffman and Ayo Oduola

… when public-interest science needs solidarity pp. 122-122

Tomasino Pace

The search continues for Kármán's St Christopher pp. 122-122

Robert Gibbs

Quantum weirdness pp. 123-123

Peter Holland

Genes, free will and intracranial musings pp. 124-125

David L. Hull

Crushed by the Frankenstein monster pp. 125-126

Howard P. Segal

Shelling out the facts pp. 126-126

David L. Strayer

The structure of matter pp. 127-127

Harry J. Lipkin

The Oort crowd pp. 129-129

Ken MacLeod

Segmentation in silico pp. 131-132

Peter Dearden and Michael Akam

The smallest random laser pp. 133-135

Diederik Wiersma

The little devil of death pp. 135-136

Vincenzo De Laurenzi and Gerry Melino

Rock signature from the sky pp. 136-137

Robert N. Clayton

One-hit neuronal death pp. 137-139

Nathaniel Heintz

Older than they look pp. 139-140

John H. Seiradakis

The bugs from Brazil pp. 140-141

Michael Bevan

Polar lights in the Caribbean pp. 141-141

Sarah Tomlin

Bringing two hearts together pp. 141-142

Wolfgang Driever

Jet-age cleaning pp. 142-142

David Jones

A self-extending paediatric leg implant pp. 143-144

Rainer Kotz, Reinhard Windhager, Martin Dominkus, Bernd Robioneck and Holger Müller-Daniels

Preventing cyanide release from leaves pp. 144-145

Helene S. Engler, Kevin C. Spencer and Lawrence E. Gilbert

A triclosan-resistant bacterial enzyme pp. 145-146

Richard J. Heath and Charles O. Rock

Diffusion of a polymer ‘pancake’ pp. 146-146

Svetlana A. Sukhishvili, Yan Chen, Joachim D. Müller, Enrico Gratton, Kenneth S. Schweizer and Steve Granick

Transcranial magnetic stimulation and the human brain pp. 147-150

Mark Hallett

The genome sequence of the plant pathogen Xylella fastidiosa pp. 151-157

A. J. G. Simpson, F.C. Reinach, P. Arruda, F. A. Abreu, M. Acencio, R. Alvarenga, L. M. C. Alves, J. E. Araya, G. S. Baia, C. S. Baptista, M. H. Barros, E. D. Bonaccorsi, S. Bordin, J. M. Bové, M. R. S. Briones, M. R. P. Bueno, A. A. Camargo, L. E. A. Camargo, D. M. Carraro, H. Carrer, N. B. Colauto, C. Colombo, F. F. Costa, M. C. R. Costa, C. M. Costa-Neto, L. L. Coutinho, M. Cristofani, E. Dias-Neto, C. Docena, H. El-Dorry, A. P. Facincani, A. J. S. Ferreira, V. C. A. Ferreira, J. A. Ferro, J. S. Fraga, S. C. França, M. C. Franco, M. Frohme, L. R. Furlan, M. Garnier, G. H. Goldman, M. H. S. Goldman, S. L. Gomes, A. Gruber, P. L. Ho, J. D. Hoheisel, M. L. Junqueira, E. L. Kemper, J.P. Kitajima, J. E. Krieger, E. E. Kuramae, F. Laigret, M. R. Lambais, L. C. C. Leite, E. G. M. Lemos, M. V. F. Lemos, S. A. Lopes, C. R. Lopes, J. A. Machado, M. A. Machado, A. M. B. N. Madeira, H. M. F. Madeira, C. L. Marino, M. V. Marques, E. A. L. Martins, E. M. F. Martins, A. Y. Matsukuma, C. F. M. Menck, E. C. Miracca, C. Y. Miyaki, C. B. Monteiro-Vitorello, D. H. Moon, M. A. Nagai, A. L. T. O. Nascimento, L. E. S. Netto, A. Nhani, F. G. Nobrega, L. R. Nunes, M. A. Oliveira, M. C. de Oliveira, R. C. de Oliveira, D. A. Palmieri, A. Paris, B. R. Peixoto, G. A. G. Pereira, H. A. Pereira, J. B. Pesquero, R. B. Quaggio, P. G. Roberto, V. Rodrigues, A. J. de M. Rosa, V. E. de Rosa, R. G. de Sá, R. V. Santelli, H. E. Sawasaki, A. C. R. da Silva, A. M. da Silva, F. R. da Silva, W. A. Silva, J. F. da Silveira, M. L. Z. Silvestri, W. J. Siqueira, A. A. de Souza, A. P. de Souza, M. F. Terenzi, D. Truffi, S. M. Tsai, M. H. Tsuhako, H. Vallada, M. A. Van Sluys, S. Verjovski-Almeida, A. L. Vettore, M. A. Zago, M. Zatz, J. Meidanis and J. C. Setubal

A large age for the pulsar B1757-24 from an upper limit on its proper motion pp. 158-160

B. M. Gaensler and D. A. Frail

Realignment of the flux-line lattice by a change in the symmetry of superconductivity in UPt3 pp. 160-164

Andrew Huxley, Pierre Rodière, Donald McK. Paul, Niels van Dijk, Robert Cubitt and Jacques Flouquet

Shaped-pulse optimization of coherent emission of high-harmonic soft X-rays pp. 164-166

R. Bartels, S. Backus, E. Zeek, L. Misoguti, G. Vdovin, I. P. Christov, M. M. Murnane and H. C. Kapteyn

Configurational entropy and diffusivity of supercooled water pp. 166-169

Antonio Scala, Francis W. Starr, Emilia La Nave, Francesco Sciortino and H. Eugene Stanley

Electronic connection to the interior of a mesoporous insulator with nanowires of crystalline RuO2 pp. 169-172

Joseph V. Ryan, Alan D. Berry, Michele L. Anderson, Jeffrey W. Long, Rhonda M. Stroud, Veronica M. Cepak, Valerie M. Browning, Debra R. Rolison and Celia I. Merzbacher

Determining the temperature of petroleum formation from the kinetic properties of petroleum asphaltenes pp. 173-176

Rolando di Primio, Brian Horsfield and Mario A. Guzman-Vega

Anomalous 17O compositions in massive sulphate deposits on the Earth pp. 176-178

Huiming Bao, Mark H. Thiemens, James Farquhar, Douglas A. Campbell, Charles Chi-Woo Lee, Klaus Heine and David B. Loope

Determining multiple length scales in rocks pp. 178-181

Yi-Qiao Song, Seungoh Ryu and Pabitra N. Sen

Cadmium toxicity among wildlife in the Colorado Rocky Mountains pp. 181-183

James R. Larison, Gene E. Likens, John W. Fitzpatrick and J. G. Crock

Competition induces adaptive shifts in caste ratios of a polyembryonic wasp pp. 183-186

Jeffrey A. Harvey, Laura S. Corley and Michael R. Strand

Condition-dependent signalling of genetic variation in stalk-eyed flies pp. 186-188

Patrice David, Tracey Bjorksten, Kevin Fowler and Andrew Pomiankowski

The segment polarity network is a robust developmental module pp. 188-192

George von Dassow, Eli Meir, Edwin M. Munro and Garrett M. Odell

A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development pp. 192-195

Erik Kupperman, Songzhu An, Nick Osborne, Steven Waldron and Didier Y. R. Stainier

A one-hit model of cell death in inherited neuronal degenerations pp. 195-199

Geoff Clarke, Richard A. Collins, Blair R. Leavitt, David F. Andrews, Michael R. Hayden, Charles J. Lumsden and Roderick R. McInnes

Genetic ablation of parathyroid glands reveals another source of parathyroid hormone pp. 199-203

Thomas Günther, Zhou-Feng Chen, Jaesang Kim, Matthias Priemel, Johannes M. Rueger, Michael Amling, Jane M. Moseley, T. John Martin, David J. Anderson and Gerard Karsenty

A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits pp. 203-207

Hiroshi Okamoto, Fumihiko Yonemori, Korekiyo Wakitani, Takashi Minowa, Kimiya Maeda and Hisashi Shinkai

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras pp. 207-210

Mark Pearson, Roberta Carbone, Carla Sebastiani, Mario Cioce, Marta Fagioli, Shin’ichi Saito, Yuichiro Higashimoto, Ettore Appella, Saverio Minucci, Pier Paolo Pandolfi and Pier Giuseppe Pelicci

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response pp. 210-215

Shang Li, Nicholas S. Y. Ting, Lei Zheng, Phang-Lang Chen, Yael Ziv, Yosef Shiloh, Eva Y.-H. P. Lee and Wen-Hwa Lee

2000, volume 406, articles 6791

African scientists join colleagues in affirming HIV's role in AIDS… pp. 3-3

Michael Cherry

…but advisory panel remains divided pp. 3-3

Michael Cherry

Royal Society warns on hormone disrupters pp. 4-4

Natasha Loder

Study compares chimps and people pp. 4-4

Robert Triendl

NIH urged to cap profits made on publicly funded research pp. 5-5

Colin Macilwain

Indian space agency sets its sight on a mission to the Moon pp. 5-5

K. S. Jayaraman

Good news for German genome research… pp. 6-6

Alison Abbott

…but proposed panel may hamper Italian gene researchers pp. 6-6

Alison Abbott

Self-policing backed for research on humans pp. 7-7

Colin Macilwain

Austrian physics meeting passes without boycott pp. 7-7

Quirin Schiermeier

New law threatens to undermine genetics in New Zealand pp. 8-8

Peter Pockley

Galileo set for suicide flight pp. 8-8

Heather McCabe

Astronomers fight to save telescope pp. 8-8

Rex Dalton

Will souped up salmon sink or swim? pp. 10-12

Tony Reichhardt

How can we build a ‘knowledge economy’ if research is handcuffed? pp. 13-13

Jack A. Heinemann

Climate-change analysis has been changing too pp. 13-13

John B. Robinson and Stewart J. Cohen

Unrealistic promises on AIDS fuel scepticism pp. 13-13

Dan Dorritie

A call for a chlorine sunset pp. 17-18

Terry Collins

Sexual trade-offs pp. 18-19

A. H. Harcourt

Misplaced nostalgia for a bygone era? pp. 19-20

Daniel S. Greenberg

Turning the key to an adolescent talent pp. 20-20

John L. Casti

Epistemology engines pp. 21-21

Don Ihde

The abdication of Pope Mary III pp. 23-23

Robert J. Sawyer

Schrödinger's cat is now fat pp. 25-26

Gianni Blatter

A cellular rescue team pp. 27-29

Joel L. Pomerantz and David Baltimore

Why trapped atoms are attractive pp. 29-30

James Anglin

An unbearable beating by light? pp. 30-31

Anne B. Britt

Phosphorus, the staff of life pp. 31-33

David M. Karl

Growth in the fast lane pp. 31-31

Vincent Dusastre

Parasites take control pp. 33-34

Richard D. Gregory and Peter J. Hudson

Green smelters pp. 34-34

David Jones

Detection of preinvasive cancer cells pp. 35-36

V. Backman, M. B. Wallace, L. T. Perelman, J. T. Arendt, R. Gurjar, M. G. Müller, Q. Zhang, G. Zonios, E. Kline, T. McGillican, S. Shapshay, T. Valdez, K. Badizadegan, J. M. Crawford, M. Fitzmaurice, S. Kabani, H. S. Levin, M. Seiler, R. R. Dasari, I. Itzkan, J. Van Dam and M. S. Feld

Degradation of plant cell walls by a nematode pp. 36-37

Herman Popeijus, Hein Overmars, John Jones, Vivian Blok, Aska Goverse, Johannes Helder, Arjen Schots, Jaap Bakker and Geert Smant

Phosphite oxidation by sulphate reduction pp. 37-37

Bernhard Schink and Michael Friedrich

Inspiration for optimization from social insect behaviour pp. 39-42

E. Bonabeau, M. Dorigo and G. Theraulaz

Quantum superposition of distinct macroscopic states pp. 43-46

Jonathan R. Friedman, Vijay Patel, W. Chen, S. K. Tolpygo and J. E. Lukens

Generation and detection of phase-coherent current-driven magnons in magnetic multilayers pp. 46-48

M. Tsoi, A. G. M. Jansen, J. Bass, W.-C. Chiang, V. Tsoi and P. Wyder

Self-directed growth of molecular nanostructures on silicon pp. 48-51

G. P. Lopinski, D. D. M. Wayner and R. A. Wolkow

Direct measurement of hole transport dynamics in DNA pp. 51-53

Frederick D. Lewis, Xiaoyang Liu, Jianqin Liu, Scott E. Miller, Ryan T. Hayes and Michael R. Wasielewski

Phosphate concentrations in lakes pp. 54-56

Jeff J. Hudson, William D. Taylor and David W. Schindler

The sedimentary structure of linear sand dunes pp. 56-59

C. S. Bristow, S. D. Bailey and N. Lancaster

The formation of plagioclase chains during convective transfer in basaltic magma pp. 59-61

Anthony R. Philpotts and Loretta D. Dickson

Valuation of consumption and sale of forest goods from a Central American rain forest pp. 62-63

Ricardo Godoy, David Wilkie, Han Overman, Adoni Cubas, Glenda Cubas, Josefien Demmer, Kendra McSweeney and Nicholas Brokaw

Parallel evolution of virulence in pathogenic Escherichia coli pp. 64-67

Sean D. Reid, Corinne J. Herbelin, Alyssa C. Bumbaugh, Robert K. Selander and Thomas S. Whittam

Negative genetic correlation between male sexual attractiveness and survival pp. 67-70

Robert Brooks

Identification of receptors for neuromedin U and its role in feeding pp. 70-74

Andrew D. Howard, Ruiping Wang, Sheng-Shung Pong, Theodore N. Mellin, Alison Strack, Xiao-Ming Guan, Zhizhen Zeng, David L. Williams, Scott D. Feighner, Christian N. Nunes, Beth Murphy, Judith N. Stair, Hong Yu, Qingping Jiang, Michelle K. Clements, Carina P. Tan, Karen K. McKee, Donna L. Hreniuk, Terrence P. McDonald, Kevin R. Lynch, Jilly F. Evans, Christopher P. Austin, C. Thomas Caskey, Lex H. T. Van der Ploeg and Qingyun Liu

Initiation of neural induction by FGF signalling before gastrulation pp. 74-78

Andrea Streit, Alyson J. Berliner, Costis Papanayotou, Andrés Sirulnik and Claudio D. Stern

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2 pp. 78-81

Miyoko Higuchi, Stefan Maas, Frank N. Single, Jochen Hartner, Andrei Rozov, Nail Burnashev, Dirk Feldmeyer, Rolf Sprengel and Peter H. Seeburg

Therapeutic haemoglobin synthesis in β-thalassaemic mice expressing lentivirus-encoded human β-globin pp. 82-86

Chad May, Stefano Rivella, John Callegari, Glenn Heller, Karen M. L. Gaensler, Lucio Luzzatto and Michel Sadelain

Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation pp. 86-90

Klaus P. Hoeflich, Juan Luo, Elizabeth A. Rubie, Ming-Sound Tsao, Ou Jin and James R. Woodgett

Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth pp. 90-94

Gefeng Zhu, Paul T. Spellman, Tom Volpe, Patrick O. Brown, David Botstein, Trisha N. Davis and Bruce Futcher

Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters pp. 94-98

Manfred Koranda, Alexander Schleiffer, Lukas Endler and Gustav Ammerer

Elevated UV-B radiation reduces genome stability in plants pp. 98-101

Gerhard Ries, Werner Heller, Holger Puchta, Heinrich Sandermann, Harald K. Seidlitz and Barbara Hohn

Structure of the dimerized hormone-binding domain of a guanylyl- cyclase-coupled receptor pp. 101-104

Focco van den Akker, Xiaolun Zhang, Masaru Miyagi, Xuewen Huo, Kunio S. Misono and Vivien C. Yee

Laying a firm foundation for interdisciplinary research endeavours pp. 107-108

Diane Gershon