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2007, volume 450, articles 7173

Sampaolesi et al. reply pp. E23-E25

Maurilio Sampaolesi, Stephane Blot, Roberto Bottinelli and Giulio Cossu

Stem cell treatment of dystrophic dogs pp. E23-E23

Allan H. Bretag

Physicists make ripples with their 'magic carpet' pp. 138-138

Philip Ball

News 2007 pp. 1134-1135

Daniel Cressey

Climate deal agreed in Bali showdown pp. 1136-1137

Olive Heffernan

Exchange rate hits US researchers pp. 1136-1136

Daniel Cressey

Snapshot pp. 1136-1136

Emma Marris

Q&A: Siti Fadilah Supari pp. 1137-1137

Declan Butler

Small advances pp. 1141-1141

David Goldston

Regulator under siege pp. 1143-1143

Meredith Wadman

2007 Gallery: Images of the Year pp. 1144-1149

Emma Marris

Newsmaker of the year: Rajendra Pachauri pp. 1150-1155

Gabrielle Walker

Come all ye scientists, busy and exhausted. O come ye, O come ye, out of the lab pp. 1156-1156

Richard J. Ladle, Ana C. M. Malhado and Peter A. Todd

Public control could be a nightmare for researchers pp. 1156-1156

Dan Graur

A brief proposal, 150 words pp. 1156-1156

Alice Flaherty

Tracking early arrivals on the Nature trail pp. 1156-1156

Helmut Zacharias

Space travel's no problem, but mice? They're scary pp. 1156-1156

Eng H. Lo

Professor's little helper pp. 1157-1159

Barbara Sahakian and Sharon Morein-Zamir

Our social roots pp. 1160-1161

Sarah F. Brosnan

Taxonomy on trial pp. 1161-1161

Henry Nicholls

Fruits of their labour pp. 1162-1163

Susan J. Mazer

Magic squares and circles pp. 1162-1162

Jared Wunsch

Glitter bugs pp. 1163-1163

Nick Thomas

Multicultural legacy pp. 1163-1164

George Gheverghese Joseph

The demise of the lone author pp. 1165-1165

Mott Greene

A quantum less quirky pp. 1167-1168

Seth Lloyd

One-stop shop pp. 1168-1169

Jonathan W. Uhr

A younger Moon pp. 1169-1170

Alan Brandon

The dance of domains pp. 1171-1172

Joseph D. Puglisi

Charge of the light brigade pp. 1172-1173

David J. Nesbitt

Neighbourly synapses pp. 1173-1175

Bernardo L. Sabatini

The art of illumination pp. 1175-1175

Liesbeth Venema

New generation of combs pp. 1175-1176

Steven T. Cundiff

Superconductivity without phonons pp. 1177-1183

P. Monthoux, D. Pines and G. G. Lonzarich

After a dozen years of progress the origin of angiosperms is still a great mystery pp. 1184-1189

Michael W. Frohlich and Mark W. Chase

Whales originated from aquatic artiodactyls in the Eocene epoch of India pp. 1190-1194

J. G. M. Thewissen, Lisa Noelle Cooper, Mark T. Clementz, Sunil Bajpai and B. N. Tiwari

Locally dynamic synaptic learning rules in pyramidal neuron dendrites pp. 1195-1200

Christopher D. Harvey and Karel Svoboda

Structural basis for gate-DNA recognition and bending by type IIA topoisomerases pp. 1201-1205

Ken C. Dong and James M. Berger

Late formation and prolonged differentiation of the Moon inferred from W isotopes in lunar metals pp. 1206-1209

M. Touboul, T. Kleine, B. Bourdon, H. Palme and R. Wieler

Internal motions of a quasiparticle governing its ultrafast nonlinear response pp. 1210-1213

P. Gaal, W. Kuehn, K. Reimann, M. Woerner, T. Elsaesser and R. Hey

Optical frequency comb generation from a monolithic microresonator pp. 1214-1217

P. Del’Haye, A. Schliesser, O. Arcizet, T. Wilken, R. Holzwarth and T. J. Kippenberg

Environmental precursors to rapid light carbon injection at the Palaeocene/Eocene boundary pp. 1218-1221

Appy Sluijs, Henk Brinkhuis, Stefan Schouten, Steven M. Bohaty, Cédric M. John, James C. Zachos, Gert-Jan Reichart, Jaap S. Sinninghe Damsté, Erica M. Crouch and Gerald R. Dickens

Trench-parallel flow and seismic anisotropy in the Mariana and Andean subduction systems pp. 1222-1225

Erik A. Kneller and Peter E. van Keken

Allometric degree distributions facilitate food-web stability pp. 1226-1229

Sonja B. Otto, Björn C. Rall and Ulrich Brose

Nanog safeguards pluripotency and mediates germline development pp. 1230-1234

Ian Chambers, Jose Silva, Douglas Colby, Jennifer Nichols, Bianca Nijmeijer, Morag Robertson, Jan Vrana, Ken Jones, Lars Grotewold and Austin Smith

Isolation of rare circulating tumour cells in cancer patients by microchip technology pp. 1235-1239

Sunitha Nagrath, Lecia V. Sequist, Shyamala Maheswaran, Daphne W. Bell, Daniel Irimia, Lindsey Ulkus, Matthew R. Smith, Eunice L. Kwak, Subba Digumarthy, Alona Muzikansky, Paula Ryan, Ulysses J. Balis, Ronald G. Tompkins, Daniel A. Haber and Mehmet Toner

Performance variability enables adaptive plasticity of ‘crystallized’ adult birdsong pp. 1240-1244

Evren C. Tumer and Michael S. Brainard

High-fidelity transmission of sensory information by single cerebellar mossy fibre boutons pp. 1245-1248

Ede A. Rancz, Taro Ishikawa, Ian Duguid, Paul Chadderton, Séverine Mahon and Michael Häusser

Stochastic gene expression out-of-steady-state in the cyanobacterial circadian clock pp. 1249-1252

Jeffrey R. Chabot, Juan M. Pedraza, Prashant Luitel and Alexander van Oudenaarden

Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis pp. 1253-1257

Miguel A. Sanjuan, Christopher P. Dillon, Stephen W. G. Tait, Simon Moshiach, Frank Dorsey, Samuel Connell, Masaaki Komatsu, Keiji Tanaka, John L. Cleveland, Sebo Withoff and Douglas R. Green

Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin pp. 1258-1262

Kristijan Ramadan, Roland Bruderer, Fabio M. Spiga, Oliver Popp, Tina Baur, Monica Gotta and Hemmo H. Meyer

Visualizing spatially correlated dynamics that directs RNA conformational transitions pp. 1263-1267

Qi Zhang, Andrew C. Stelzer, Charles K. Fisher and Hashim M. Al-Hashimi

Segrosome structure revealed by a complex of ParR with centromere DNA pp. 1268-1271

Maria A. Schumacher, Tiffany C. Glover, Anthony J. Brzoska, Slade O. Jensen, Thomas D. Dunham, Ronald A. Skurray and Neville Firth

Erratum: The effects of molecular noise and size control on variability in the budding yeast cell cycle pp. 1272-1272

Stefano Di Talia, Jan M. Skotheim, James M. Bean, Eric D. Siggia and Frederick R. Cross

Prospect pp. 1273-1273

Gene Russo

To look too closely pp. 1276-1276

Paul Grainger

2007, volume 450, articles 7172

Kimberlite ascent and eruption pp. E21-E21

R. S. J. Sparks, R. J. Brown, M. Field and M. Gilbertson

Wilson & Head reply pp. E22-E22

Lionel Wilson and James W. Head

Journal club pp. 925-925

Paul Mulvaney

London to host ambitious research hub pp. 926-927

Andrea Chipman

Nuclear-reactor closure hits cancer tests pp. 927-927

Hannah Hoag

Enigmatic clouds illuminated pp. 927-927

Alexandra Witze

Showdown for Europe pp. 928-929

Alison Abbott and Quirin Schiermeier

Promise boiling over pp. 934-935

Kurt Kleiner

Market watch pp. 935-935

Colin Macilwain

Gardening: A garden for all climates pp. 937-939

Emma Marris

Archaeology: Pieces of the puzzle pp. 940-941

Rex Dalton

Abnormal neuroscience: Scanning psychopaths pp. 942-944

Alison Abbott

All fishing nations must unite to cut subsidies pp. 945-945

Ussif Sumaila and Daniel Pauly

Debate over flood-proofing effects of planting forests pp. 945-945

Ian R. Calder, James Smyle and Bruce Aylward

Motivation needed to cure lifestyle diseases pp. 945-945

Werner Waldhäusl

Educational success must start in Pakistan's schools pp. 945-945

Masroor Bangesh

Small matters, big issues pp. 946-947

Harriet Coles

Young planet-savers pp. 947-948

Tom Standage

Hawking's fact and fiction pp. 949-949

George F. R. Ellis

Stones, bones and stories pp. 949-950

Henry Gee

Star tales pp. 950-950

Mark Brake

To bodily go pp. 951-951

Ian Jones

Mathematics not shopping pp. 951-952

Joanna Sabatino-Hernandez

The scene is set pp. 952-952

Glenn Murphy

Rogue waves surface in light pp. 953-954

Dong-Il Yeom and Benjamin J. Eggleton

Differential parasite drive pp. 955-956

Giel G. van Dooren and Geoffrey I. McFadden

Dim view of past clashes pp. 956-957

Curtis Struck

Ion pumps made crystal clear pp. 957-959

David C. Gadsby

Genome under surveillance pp. 959-960

Karen M. Arndt

Cool conditions for mobile ions pp. 960-961

Michael A. Hayward and Matthew J. Rosseinsky

Gene H. Golub (1932–2007) pp. 962-962

Lloyd N. Trefethen

Proteins to proteomes pp. 963-963

Tanguy Chouard and Joshua Finkelstein

Dynamic personalities of proteins pp. 964-972

Katherine Henzler-Wildman and Dorothee Kern

The molecular sociology of the cell pp. 973-982

Carol V. Robinson, Andrej Sali and Wolfgang Baumeister

The origin of protein interactions and allostery in colocalization pp. 983-990

John Kuriyan and David Eisenberg

The biological impact of mass-spectrometry-based proteomics pp. 991-1000

Benjamin F. Cravatt, Gabriel M. Simon and John R. Yates

Reaching for high-hanging fruit in drug discovery at protein–protein interfaces pp. 1001-1009

James A. Wells and Christopher L. McClendon

Transformation and diversification in early mammal evolution pp. 1011-1019

Zhe-Xi Luo

Two stellar components in the halo of the Milky Way pp. 1020-1025

Daniela Carollo, Timothy C. Beers, Young Sun Lee, Masashi Chiba, John E. Norris, Ronald Wilhelm, Thirupathi Sivarani, Brian Marsteller, Jeffrey A. Munn, Coryn A. L. Bailer-Jones, Paola Re Fiorentin and Donald G. York

Molecular code for transmembrane-helix recognition by the Sec61 translocon pp. 1026-1030

Tara Hessa, Nadja M. Meindl-Beinker, Andreas Bernsel, Hyun Kim, Yoko Sato, Mirjam Lerch-Bader, IngMarie Nilsson, Stephen H. White and Gunnar von Heijne

Chromatin remodelling at promoters suppresses antisense transcription pp. 1031-1035

Iestyn Whitehouse, Oliver J. Rando, Jeff Delrow and Toshio Tsukiyama

The structural basis of calcium transport by the calcium pump pp. 1036-1042

Claus Olesen, Martin Picard, Anne-Marie Lund Winther, Claus Gyrup, J. Preben Morth, Claus Oxvig, Jesper Vuust Møller and Poul Nissen

Crystal structure of the sodium–potassium pump pp. 1043-1049

J. Preben Morth, Bjørn P. Pedersen, Mads S. Toustrup-Jensen, Thomas L.-M. Sørensen, Janne Petersen, Jens Peter Andersen, Bente Vilsen and Poul Nissen

A dynamic, rotating ring current around Saturn pp. 1050-1053

S. M. Krimigis, N. Sergis, D. G. Mitchell, D. C. Hamilton and N. Krupp

Optical rogue waves pp. 1054-1057

D. R. Solli, C. Ropers, P. Koonath and B. Jalali

A distinct bosonic mode in an electron-doped high-transition-temperature superconductor pp. 1058-1061

F. C. Niestemski, S. Kunwar, S. Zhou, Shiliang Li, H. Ding, Ziqiang Wang, Pengcheng Dai and V. Madhavan

Infinite-layer iron oxide with a square-planar coordination pp. 1062-1065

Y. Tsujimoto, C. Tassel, N. Hayashi, T. Watanabe, H. Kageyama, K. Yoshimura, M. Takano, M. Ceretti, C. Ritter and W. Paulus

Effect of remote sea surface temperature change on tropical cyclone potential intensity pp. 1066-1070

Gabriel A. Vecchi and Brian J. Soden

Dynamics of Mid-Palaeocene North Atlantic rifting linked with European intra-plate deformations pp. 1071-1074

Søren B. Nielsen, Randell Stephenson and Erik Thomsen

Fetal load and the evolution of lumbar lordosis in bipedal hominins pp. 1075-1078

Katherine K. Whitcome, Liza J. Shapiro and Daniel E. Lieberman

Coevolution with viruses drives the evolution of bacterial mutation rates pp. 1079-1081

Csaba Pal, María D. Maciá, Antonio Oliver, Ira Schachar and Angus Buckling

Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3 pp. 1082-1085

Daniel O. Hart, Tamal Raha, Nathan D. Lawson and Michael R. Green

CLOCK-mediated acetylation of BMAL1 controls circadian function pp. 1086-1090

Jun Hirayama, Saurabh Sahar, Benedetto Grimaldi, Teruya Tamaru, Ken Takamatsu, Yasukazu Nakahata and Paolo Sassone-Corsi

Distinct physiological states of Plasmodium falciparum in malaria-infected patients pp. 1091-1095

J. P. Daily, D. Scanfeld, N. Pochet, K. Le Roch, D. Plouffe, M. Kamal, O. Sarr, S. Mboup, O. Ndir, D. Wypij, K. Levasseur, E. Thomas, P. Tamayo, C. Dong, Y. Zhou, E. S. Lander, D. Ndiaye, D. Wirth, E. A. Winzeler, J. P. Mesirov and A. Regev

A viral microRNA functions as an orthologue of cellular miR-155 pp. 1096-1099

Eva Gottwein, Neelanjan Mukherjee, Christoph Sachse, Corina Frenzel, William H. Majoros, Jen-Tsan A. Chi, Ravi Braich, Muthiah Manoharan, Jürgen Soutschek, Uwe Ohler and Bryan R. Cullen

Reconstitution of a microtubule plus-end tracking system in vitro pp. 1100-1105

Peter Bieling, Liedewij Laan, Henry Schek, E. Laura Munteanu, Linda Sandblad, Marileen Dogterom, Damian Brunner and Thomas Surrey

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination pp. 1106-1110

Adam G. W. Matthews, Alex J. Kuo, Santiago Ramón-Maiques, Sunmi Han, Karen S. Champagne, Dmitri Ivanov, Mercedes Gallardo, Dylan Carney, Peggie Cheung, David N. Ciccone, Kay L. Walter, Paul J. Utz, Yang Shi, Tatiana G. Kutateladze, Wei Yang, Or Gozani and Marjorie A. Oettinger

Crystal structure of the plasma membrane proton pump pp. 1111-1114

Bjørn P. Pedersen, Morten J. Buch-Pedersen, J. Preben Morth, Michael G. Palmgren and Poul Nissen

Delivering the future pp. 1119-1120

Nathan Blow

Prospects pp. 1123-1123

Gene Russo

Up, down, and out pp. 1124-1125

Peter Jordan

Recoper pp. 1126-1126

Neal Asher

2007, volume 450, articles 7171

Effective global conservation strategies pp. E19-E19

Ana S. L. Rodrigues

Grenyer et al. reply pp. E20-E20

Richard Grenyer, C. David L. Orme, T. Jonathan Davies, Sarah F. Jackson, Richard G. Davies, Valerie A. Olson, Kate E. Jones, Kevin J. Gaston, Tim M. Blackburn, Gavin H. Thomas, Peter M. Bennett, Pamela C. Rasmussen, Tzung-Su Ding, John L. Gittleman and Ian P. F. Owens

Journal club pp. 765-765

Sarah E. Hitchcock-DeGregori

UN talks only one part of the negotiations needed on climate pp. 767-767

Jeff Tollefson

Solar power: California's latest gold rush pp. 768-769

Declan Butler

Model predicts structure of crystals pp. 771-771

Katharine Sanderson

Saudi-Italian biomedical institute gets go-ahead pp. 772-772

Alison Abbott

Asia plans first cancer network pp. 772-773

David Cyranoski

Fund boost for German science pp. 773-773

Quirin Schiermeier

Smart networking pp. 777-777

Katharine Sanderson

Earth Monitoring: The planetary panopticon pp. 778-780

Declan Butler

Earth Monitoring: Observing the ocean from within pp. 780-781

Quirin Schiermeier

Earth Monitoring: Not enough eyes on the prize pp. 782-785

Alexandra Witze

Earth Monitoring: The crucial measurement pp. 785-786

Amanda Haag

Thought: a different perspective pp. 788-788

Marc D. Hauser

Thought: book review has my ideas back to front pp. 788-788

Steven Pinker

Chance to learn and teach in the developing world pp. 788-788

Tim Caro and Monique Borgerhoff Mulder

Few women join ranks of Germany's academic élite pp. 788-788

Laura Niven

Cinderella science pp. 789-790

Euan Nisbet

Vigilance is not enough pp. 791-792

Walter Boyce

The ultimate Romantic adventure pp. 793-794

Andrew Robinson

Size matters, sometimes pp. 794-794

Steven Murawski

The importance of nothing pp. 795-795

Lawrence Rudnick

A fresh perspective pp. 795-795

Jennifer Meyer

Science in culture pp. 796-796

Martin Kemp

Whole Earth comes into focus pp. 797-797

Stewart Brand

Missing links pp. 799-800

Bart O. Roep

Shear madness pp. 800-801

Alan T. Dorsey and David A. Huse

Still special pp. 801-803

Giovanni Amelino-Camelia

Immune pact with the enemy pp. 803-804

Cornelis J. M. Melief

Bilingual bacteria pp. 805-807

Matthew R. Parsek

Slush find pp. 807-808

Alan J. Kaufman

Siberian salt in the cellar pp. 808-808

Richard Webb

Arthur Kornberg (1918–2007) pp. 809-809

Tania A. Baker

Green chemistry pp. 810-812

Martyn Poliakoff and Pete Licence

Snowball Earth prevention by dissolved organic carbon remineralization pp. 813-818

W. Richard Peltier, Yonggang Liu and John W. Crowley

Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia pp. 819-824

Wilhelm Roell, Thorsten Lewalter, Philipp Sasse, Yvonne N. Tallini, Bum-Rak Choi, Martin Breitbach, Robert Doran, Ulrich M. Becher, Seong-Min Hwang, Toktam Bostani, Julia von Maltzahn, Andreas Hofmann, Shaun Reining, Britta Eiberger, Bethann Gabris, Alexander Pfeifer, Armin Welz, Klaus Willecke, Guy Salama, Jan W. Schrickel, Michael I. Kotlikoff and Bernd K. Fleischmann

Bv8 regulates myeloid-cell-dependent tumour angiogenesis pp. 825-831

Farbod Shojaei, Xiumin Wu, Cuiling Zhong, Lanlan Yu, Xiao-Huan Liang, Jenny Yao, Dominique Blanchard, Carlos Bais, Franklin V. Peale, Nicholas van Bruggen, Calvin Ho, Jed Ross, Martha Tan, Richard A. D. Carano, Y. Gloria Meng and Napoleone Ferrara

The molecular architecture of cadherins in native epidermal desmosomes pp. 832-837

Ashraf Al-Amoudi, Daniel Castaño Díez, Matthew J. Betts and Achilleas S. Frangakis

Intrinsic motions along an enzymatic reaction trajectory pp. 838-844

Katherine A. Henzler-Wildman, Vu Thai, Ming Lei, Maria Ott, Magnus Wolf-Watz, Tim Fenn, Ed Pozharski, Mark A. Wilson, Gregory A. Petsko, Martin Karplus, Christian G. Hübner and Dorothee Kern

A stability limit for the atmospheres of giant extrasolar planets pp. 845-848

Tommi T. Koskinen, Alan D. Aylward and Steve Miller

Cryptomare magmatism 4.35 Gyr ago recorded in lunar meteorite Kalahari 009 pp. 849-852

Kentaro Terada, Mahesh Anand, Anna K. Sokol, Addi Bischoff and Yuji Sano

Low-temperature shear modulus changes in solid 4He and connection to supersolidity pp. 853-856

James Day and John Beamish

Controlling cavity reflectivity with a single quantum dot pp. 857-861

Dirk Englund, Andrei Faraon, Ilya Fushman, Nick Stoltz, Pierre Petroff and Jelena Vučković

Linear and nonlinear optical spectroscopy of a strongly coupled microdisk–quantum dot system pp. 862-865

Kartik Srinivasan and Oskar Painter

A crystallizing dense magma ocean at the base of the Earth’s mantle pp. 866-869

S. Labrosse, J. W. Hernlund and N. Coltice

Host–parasite ‘Red Queen’ dynamics archived in pond sediment pp. 870-873

Ellen Decaestecker, Sabrina Gaba, Joost A. M. Raeymaekers, Robby Stoks, Liesbeth Van Kerckhoven, Dieter Ebert and Luc De Meester

Methanotrophy below pH 1 by a new Verrucomicrobia species pp. 874-878

Arjan Pol, Klaas Heijmans, Harry R. Harhangi, Dario Tedesco, Mike S. M. Jetten and Huub J. M. Op den Camp

Methane oxidation by an extremely acidophilic bacterium of the phylum Verrucomicrobia pp. 879-882

Peter F. Dunfield, Anton Yuryev, Pavel Senin, Angela V. Smirnova, Matthew B. Stott, Shaobin Hou, Binh Ly, Jimmy H. Saw, Zhemin Zhou, Yan Ren, Jianmei Wang, Bruce W. Mountain, Michelle A. Crowe, Tina M. Weatherby, Paul L. E. Bodelier, Werner Liesack, Lu Feng, Lei Wang and Maqsudul Alam

The major Vibrio cholerae autoinducer and its role in virulence factor production pp. 883-886

Douglas A. Higgins, Megan E. Pomianek, Christina M. Kraml, Ronald K. Taylor, Martin F. Semmelhack and Bonnie L. Bassler

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A pp. 887-892

Sergey Nejentsev, Joanna M. M. Howson, Neil M. Walker, Jeffrey Szeszko, Sarah F. Field, Helen E. Stevens, Pamela Reynolds, Matthew Hardy, Erna King, Jennifer Masters, John Hulme, Lisa M. Maier, Deborah Smyth, Rebecca Bailey, Jason D. Cooper, Gloria Ribas, R. Duncan Campbell, David G. Clayton and John A. Todd

Characterizing the cancer genome in lung adenocarcinoma pp. 893-898

Barbara A. Weir, Michele S. Woo, Gad Getz, Sven Perner, Li Ding, Rameen Beroukhim, William M. Lin, Michael A. Province, Aldi Kraja, Laura A. Johnson, Kinjal Shah, Mitsuo Sato, Roman K. Thomas, Justine A. Barletta, Ingrid B. Borecki, Stephen Broderick, Andrew C. Chang, Derek Y. Chiang, Lucian R. Chirieac, Jeonghee Cho, Yoshitaka Fujii, Adi F. Gazdar, Thomas Giordano, Heidi Greulich, Megan Hanna, Bruce E. Johnson, Mark G. Kris, Alex Lash, Ling Lin, Neal Lindeman, Elaine R. Mardis, John D. McPherson, John D. Minna, Margaret B. Morgan, Mark Nadel, Mark B. Orringer, John R. Osborne, Brad Ozenberger, Alex H. Ramos, James Robinson, Jack A. Roth, Valerie Rusch, Hidefumi Sasaki, Frances Shepherd, Carrie Sougnez, Margaret R. Spitz, Ming-Sound Tsao, David Twomey, Roel G. W. Verhaak, George M. Weinstock, David A. Wheeler, Wendy Winckler, Akihiko Yoshizawa, Soyoung Yu, Maureen F. Zakowski, Qunyuan Zhang, David G. Beer, Ignacio I. Wistuba, Mark A. Watson, Levi A. Garraway, Marc Ladanyi, William D. Travis, William Pao, Mark A. Rubin, Stacey B. Gabriel, Richard A. Gibbs, Harold E. Varmus, Richard K. Wilson, Eric S. Lander and Matthew Meyerson

Identification of protein pheromones that promote aggressive behaviour pp. 899-902

Pablo Chamero, Tobias F. Marton, Darren W. Logan, Kelly Flanagan, Jason R. Cruz, Alan Saghatelian, Benjamin F. Cravatt and Lisa Stowers

Adaptive immunity maintains occult cancer in an equilibrium state pp. 903-907

Catherine M. Koebel, William Vermi, Jeremy B. Swann, Nadeen Zerafa, Scott J. Rodig, Lloyd J. Old, Mark J. Smyth and Robert D. Schreiber

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA pp. 908-912

Jafar Sharif, Masahiro Muto, Shin-ichiro Takebayashi, Isao Suetake, Akihiro Iwamatsu, Takaho A. Endo, Jun Shinga, Yoko Mizutani-Koseki, Tetsuro Toyoda, Kunihiro Okamura, Shoji Tajima, Kohzoh Mitsuya, Masaki Okano and Haruhiko Koseki

A hierarchy of timescales in protein dynamics is linked to enzyme catalysis pp. 913-916

Katherine A. Henzler-Wildman, Ming Lei, Vu Thai, S. Jordan Kerns, Martin Karplus and Dorothee Kern

Prospects pp. 917-917

Gene Russo

Jose Alonso, director, Sanford Underground Science and Engineering Laboratory, Homestake, South Dakota pp. 918-918

Virginia Gewin

How to handle drug withdrawal pp. 918-918

Paul Smaglik

A conference too soon pp. 918-918

Chris Rowan

Life, abundant and with simple joy pp. 920-920

Sarah K. Castle

2007, volume 450, articles 7170

Ediacaran oxidation and biotic evolution pp. E17-E17

Kathleen Grey and Clive R. Calver

Fike et al. reply pp. E18-E18

D. A. Fike, J. P. Grotzinger, L. L. Pratt and R. R. Summons

Journal club pp. 589-589

Ursula Euteneuer

Loopholes in oversight rules revealed pp. 590-590

Eugenie Samuel Reich

Deforestation on the agenda at climate meeting? pp. 590-591

Jeff Tollefson

Brazil to boost science spend pp. 591-591

João Medeiros

Now in Arabic pp. 591-591

Jascha Hoffman

Monuments and instruments pp. 592-593

Emma Marris

Plant-disease controls sap outbreak responses pp. 596-596

Ewen Callaway

Graphic Detail: The real value of a scientist's wage pp. 597-597

Quirin Schiermeier

Fever pitch pp. 600-601

Heidi Ledford

Market watch pp. 601-601

Colin Macilwain

Age research: A new angle on 'old' pp. 603-605

Erika Check Hayden

Space and astronomy: The girl next door pp. 606-608

Eric Hand

Each co-author should sign to reduce risk of fraud pp. 610-610

Kevin Yager

Moon is the best witness to early Solar System history pp. 610-610

Carle M. Pieters and George A. Paulikas

Modifying theories is the fabric of scientific progress pp. 610-610

Felix E. Schweizer

Good thinking should not be wasted on bad ideas pp. 610-610

James L. Sherley

The great debate pp. 611-611

Christopher Thomas Scott

Is artificial life moving any closer? pp. 612-612

Greg Bear

On a molecular mission pp. 613-614

Maria A. Blasco

The art of arthropods pp. 613-613

Nick Thomas

Is technology unnatural? pp. 614-614

Philip Ball

The ethical regulation of science pp. 615-615

Mary Warnock

Express dispatches pp. 617-618

Andrew P. Ingersoll

The unusual suspect pp. 619-619

Colin L. Stewart

Pore puzzle pp. 621-622

John D. Aitchison and Richard W. Wozniak

Elementary resolution pp. 622-623

Christian Colliex

Sensors and synchronicity pp. 623-625

Ruth Heidelberger

A step dissected pp. 625-626

Zeynep Ökten and Manfred Schliwa

Leslie Orgel (1927–2007) pp. 627-627

Gerald F. Joyce

Venus as a more Earth-like planet pp. 629-632

Håkan Svedhem, Dmitry V. Titov, Fredric W. Taylor and Olivier Witasse

Morphology and dynamics of the upper cloud layer of Venus pp. 633-636

W. J. Markiewicz, D. V. Titov, S. S. Limaye, H. U. Keller, N. Ignatiev, R. Jaumann, N. Thomas, H. Michalik, R. Moissl and P. Russo

South-polar features on Venus similar to those near the north pole pp. 637-640

G. Piccioni, P. Drossart, A. Sanchez-Lavega, R. Hueso, F. W. Taylor, C. F. Wilson, D. Grassi, L. Zasova, M. Moriconi, A. Adriani, S. Lebonnois, A. Coradini, B. Bézard, F. Angrilli, G. Arnold, K. H. Baines, G. Bellucci, J. Benkhoff, J. P. Bibring, A. Blanco, M. I. Blecka, R. W. Carlson, A. Di Lellis, T. Encrenaz, S. Erard, S. Fonti, V. Formisano, T. Fouchet, R. Garcia, R. Haus, J. Helbert, N. I. Ignatiev, P. G. J. Irwin, Y. Langevin, M. A. Lopez-Valverde, D. Luz, L. Marinangeli, V. Orofino, A. V. Rodin, M. C. Roos-Serote, B. Saggin, D. M. Stam, D. Titov, G. Visconti and M. Zambelli

A dynamic upper atmosphere of Venus as revealed by VIRTIS on Venus Express pp. 641-645

P. Drossart, G. Piccioni, J. C. Gérard, M. A. Lopez-Valverde, A. Sanchez-Lavega, L. Zasova, R. Hueso, F. W. Taylor, B. Bézard, A. Adriani, F. Angrilli, G. Arnold, K. H. Baines, G. Bellucci, J. Benkhoff, J. P. Bibring, A. Blanco, M. I. Blecka, R. W. Carlson, A. Coradini, A. Di Lellis, T. Encrenaz, S. Erard, S. Fonti, V. Formisano, T. Fouchet, R. Garcia, R. Haus, J. Helbert, N. I. Ignatiev, P. Irwin, Y. Langevin, S. Lebonnois, D. Luz, L. Marinangeli, V. Orofino, A. V. Rodin, M. C. Roos-Serote, B. Saggin, D. M. Stam, D. Titov, G. Visconti, M. Zambelli and C. Tsang

A warm layer in Venus' cryosphere and high-altitude measurements of HF, HCl, H2O and HDO pp. 646-649

Jean-Loup Bertaux, Ann-Carine Vandaele, Oleg Korablev, E. Villard, A. Fedorova, D. Fussen, E. Quémerais, D. Belyaev, A. Mahieux, F. Montmessin, C. Muller, E. Neefs, D. Nevejans, V. Wilquet, J. P. Dubois, A. Hauchecorne, A. Stepanov, I. Vinogradov and A. Rodin

The loss of ions from Venus through the plasma wake pp. 650-653

S. Barabash, A. Fedorov, J. J. Sauvaud, R. Lundin, C. T. Russell, Y. Futaana, T. L. Zhang, H. Andersson, K. Brinkfeldt, A. Grigoriev, M. Holmström, M. Yamauchi, K. Asamura, W. Baumjohann, H. Lammer, A. J. Coates, D. O. Kataria, D. R. Linder, C. C. Curtis, K. C. Hsieh, B. R. Sandel, M. Grande, H. Gunell, H. E. J. Koskinen, E. Kallio, P. Riihelä, T. Säles, W. Schmidt, J. Kozyra, N. Krupp, M. Fränz, J. Woch, J. Luhmann, S. McKenna-Lawlor, C. Mazelle, J.-J. Thocaven, S. Orsini, R. Cerulli-Irelli, M. Mura, M. Milillo, M. Maggi, E. Roelof, P. Brandt, K. Szego, J. D. Winningham, R. A. Frahm, J. Scherrer, J. R. Sharber, P. Wurz and P. Bochsler

Little or no solar wind enters Venus’ atmosphere at solar minimum pp. 654-656

T. L. Zhang, M. Delva, W. Baumjohann, H.-U. Auster, C. Carr, C. T. Russell, S. Barabash, M. Balikhin, K. Kudela, G. Berghofer, H. K. Biernat, H. Lammer, H. Lichtenegger, W. Magnes, R. Nakamura, K. Schwingenschuh, M. Volwerk, Z. Vörös, W. Zambelli, K.-H. Fornacon, K.-H. Glassmeier, I. Richter, A. Balogh, H. Schwarzl, S. A. Pope, J. K. Shi, C. Wang, U. Motschmann and J.-P. Lebreton

The structure of Venus’ middle atmosphere and ionosphere pp. 657-660

M. Pätzold, B. Häusler, M. K. Bird, S. Tellmann, R. Mattei, S. W. Asmar, V. Dehant, W. Eidel, T. Imamura, R. A. Simpson and G. L. Tyler

Lightning on Venus inferred from whistler-mode waves in the ionosphere pp. 661-662

C. T. Russell, T. L. Zhang, M. Delva, W. Magnes, R. J. Strangeway and H. Y. Wei

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes pp. 663-669

Tom A. Rapoport

Shiga toxin induces tubular membrane invaginations for its uptake into cells pp. 670-675

Winfried Römer, Ludwig Berland, Valérie Chambon, Katharina Gaus, Barbara Windschiegl, Danièle Tenza, Mohamed R. E. Aly, Vincent Fraisier, Jean-Claude Florent, David Perrais, Christophe Lamaze, Graça Raposo, Claudia Steinem, Pierre Sens, Patricia Bassereau and Ludger Johannes

A dual-Ca2+-sensor model for neurotransmitter release in a central synapse pp. 676-682

Jianyuan Sun, Zhiping P. Pang, Dengkui Qin, Abigail T. Fahim, Roberto Adachi and Thomas C. Südhof

Determining the architectures of macromolecular assemblies pp. 683-694

Frank Alber, Svetlana Dokudovskaya, Liesbeth M. Veenhoff, Wenzhu Zhang, Julia Kipper, Damien Devos, Adisetyantari Suprapto, Orit Karni-Schmidt, Rosemary Williams, Brian T. Chait, Michael P. Rout and Andrej Sali

The molecular architecture of the nuclear pore complex pp. 695-701

Frank Alber, Svetlana Dokudovskaya, Liesbeth M. Veenhoff, Wenzhu Zhang, Julia Kipper, Damien Devos, Adisetyantari Suprapto, Orit Karni-Schmidt, Rosemary Williams, Brian T. Chait, Andrej Sali and Michael P. Rout

Element-selective imaging of atomic columns in a crystal using STEM and EELS pp. 702-704

Koji Kimoto, Toru Asaka, Takuro Nagai, Mitsuhiro Saito, Yoshio Matsui and Kazuo Ishizuka

Visualizing single-molecule diffusion in mesoporous materials pp. 705-708

Andreas Zürner, Johanna Kirstein, Markus Döblinger, Christoph Bräuchle and Thomas Bein

A diffusion mechanism for core–mantle interaction pp. 709-711

Leslie A. Hayden and E. Bruce Watson

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes pp. 712-716

Jill C. Milne, Philip D. Lambert, Simon Schenk, David P. Carney, Jesse J. Smith, David J. Gagne, Lei Jin, Olivier Boss, Robert B. Perni, Chi B. Vu, Jean E. Bemis, Roger Xie, Jeremy S. Disch, Pui Yee Ng, Joseph J. Nunes, Amy V. Lynch, Hongying Yang, Heidi Galonek, Kristine Israelian, Wendy Choy, Andre Iffland, Siva Lavu, Oliver Medvedik, David A. Sinclair, Jerrold M. Olefsky, Michael R. Jirousek, Peter J. Elliott and Christoph H. Westphal

Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism pp. 717-720

Eric Dessaud, Lin Lin Yang, Katy Hill, Barny Cox, Fausto Ulloa, Ana Ribeiro, Anita Mynett, Bennett G. Novitch and James Briscoe

p53 regulates maternal reproduction through LIF pp. 721-724

Wenwei Hu, Zhaohui Feng, Angelika K. Teresky and Arnold J. Levine

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1 pp. 725-730

Coenraad Kuijl, Nigel D. L. Savage, Marije Marsman, Adriaan W. Tuin, Lennert Janssen, David A. Egan, Mirjam Ketema, Rian van den Nieuwendijk, Susan J. F. van den Eeden, Annemieke Geluk, Alex Poot, Gijs van der Marel, Roderick L. Beijersbergen, Hermen Overkleeft, Tom H. M. Ottenhoff and Jacques Neefjes

Calcineurin sets the bandwidth for discrimination of signals during thymocyte development pp. 731-735

Elena M. Gallo, Monte M. Winslow, Kirsten Canté-Barrett, Amy N. Radermacher, Lena Ho, Lisa McGinnis, Brian Iritani, Joel R. Neilson and Gerald R. Crabtree

mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex pp. 736-740

John T. Cunningham, Joseph T. Rodgers, Daniel H. Arlow, Francisca Vazquez, Vamsi K. Mootha and Pere Puigserver

Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface pp. 741-744

Xuewu Zhang, Kerry A. Pickin, Ron Bose, Natalia Jura, Philip A. Cole and John Kuriyan

The centromere geometry essential for keeping mitosis error free is controlled by spindle forces pp. 745-749

Jadranka Lončarek, Olga Kisurina-Evgenieva, Tatiana Vinogradova, Polla Hergert, Sabrina La Terra, Tarun M. Kapoor and Alexey Khodjakov

How kinesin waits between steps pp. 750-754

Teppei Mori, Ronald D. Vale and Michio Tomishige

Prospects pp. 755-755

Paul Smaglik

Cell Mates pp. 756-757

Jacqueline Ruttimann

Richard Myers, director of Hudson-Alpha Institute for Biotechnology, Huntsville, Alabama pp. 758-758

Paul Smaglik

Authorship accountability pp. 758-758

Umesh Chandra Lavania

Double trouble pp. 758-758

Moira Sheehan

Repeating the past pp. 760-760

Peter Watts

2007, volume 450, articles 7169

Genotyping of Rhesus SCNT pluripotent stem cell lines pp. E12-E14

David S. Cram, Bi Song and Alan O. Trounson

Evidence for mantle plumes? pp. E15-E15

Don L. Anderson and James H. Natland

Bourdon et al. reply pp. E16-E16

B. Bourdon, N. M. Ribe, A. Stracke, A. Saal and S. Turner

Journal club pp. 461-461

Arturo Zychlinsky

UK 'terrorist' fights science-course ban pp. 467-467

Geoff Brumfiel

UK astronomers stunned by Gemini withdrawal pp. 468-468

Eric Hand

Proposal raises bones of contention pp. 469-469

Rex Dalton

Trip into the unknown pp. 471-471

Tatum Anderson

Marine biology: Lights in the deep pp. 472-474

Mark Schrope

Profile: Innate ability pp. 475-477

David Cyranoski

Biofuel: microalgae cut the social and ecological costs pp. 478-478

Peter J.le B. Williams

Biofuel: corn isn't the king of this growing domain pp. 478-478

C. Ford Runge and Benjamin Senauer

Research in the wild pp. 478-478

Ine Van Hoyweghen and Bart Penders

Kyoto: doing our best is no longer enough pp. 478-478

Barry W. Brook, Nick Rowley and Tim F. Flannery

Flavour and plenty pp. 479-479

Peter Barham

Time deconstructed pp. 480-481

Lawrence M. Krauss

Quests of a theoretical astronomer pp. 480-480

Owen Gingerich

Scientists on film pp. 481-482

Emma Marris

Dishing the dirt on hygiene pp. 482-482

Virginia Smith

Accommodating dissent pp. 483-483

Melissa Leach

Primates join the club pp. 485-486

Ian Wilmut and Jane Taylor

Purity rolled up in a tube pp. 486-487

Fotios Papadimitrakopoulos and Sang-Yong Ju

Woodworker's digest pp. 487-488

Andreas Brune

Sloan at five pp. 488-489

Robert C. Kennicutt

Sediment en route to oblivion pp. 490-491

Philip A. Allen

Marine manipulations pp. 491-492

Kevin R. Arrigo

Schizophrenic electrons pp. 492-493

Christian Pfleiderer and Rudi Hackl

Grand challenges in chronic non-communicable diseases pp. 494-496

Abdallah S. Daar, Peter A. Singer, Deepa Leah Persad, Stig K. Pramming, David R. Matthews, Robert Beaglehole, Alan Bernstein, Leszek K. Borysiewicz, Stephen Colagiuri, Nirmal Ganguly, Roger I. Glass, Diane T. Finegood, Jeffrey Koplan, Elizabeth G. Nabel, George Sarna, Nizal Sarrafzadegan, Richard Smith, Derek Yach and John Bell

Producing primate embryonic stem cells by somatic cell nuclear transfer pp. 497-502

J. A. Byrne, D. A. Pedersen, L. L. Clepper, M. Nelson, W. G. Sanger, S. Gokhale, D. P. Wolf and S. M. Mitalipov

Innate versus learned odour processing in the mouse olfactory bulb pp. 503-508

Ko Kobayakawa, Reiko Kobayakawa, Hideyuki Matsumoto, Yuichiro Oka, Takeshi Imai, Masahito Ikawa, Masaru Okabe, Toshio Ikeda, Shigeyoshi Itohara, Takefumi Kikusui, Kensaku Mori and Hitoshi Sakano

Human CtIP promotes DNA end resection pp. 509-514

Alessandro A. Sartori, Claudia Lukas, Julia Coates, Martin Mistrik, Shuang Fu, Jiri Bartek, Richard Baer, Jiri Lukas and Stephen P. Jackson

Crystal structure of a catalytic intermediate of the maltose transporter pp. 515-521

Michael L. Oldham, Dheeraj Khare, Florante A. Quiocho, Amy L. Davidson and Jue Chen

White dwarf stars with carbon atmospheres pp. 522-524

P. Dufour, J. Liebert, G. Fontaine and N. Behara

Coupled 142Nd–143Nd evidence for a protracted magma ocean in Mars pp. 525-528

V. Debaille, A. D. Brandon, Q. Z. Yin and B. Jacobsen

Coherent zero-state and π-state in an exciton–polariton condensate array pp. 529-532

C. W. Lai, N. Y. Kim, S. Utsunomiya, G. Roumpos, H. Deng, M. D. Fraser, T. Byrnes, P. Recher, N. Kumada, T. Fujisawa and Y. Yamamoto

Electron pockets in the Fermi surface of hole-doped high-Tc superconductors pp. 533-536

David LeBoeuf, Nicolas Doiron-Leyraud, Julien Levallois, R. Daou, J.-B. Bonnemaison, N. E. Hussey, L. Balicas, B. J. Ramshaw, Ruixing Liang, D. A. Bonn, W. N. Hardy, S. Adachi, Cyril Proust and Louis Taillefer

Dissolved organic carbon trends resulting from changes in atmospheric deposition chemistry pp. 537-540

Donald T. Monteith, John L. Stoddard, Christopher D. Evans, Heleen A. de Wit, Martin Forsius, Tore Høgåsen, Anders Wilander, Brit Lisa Skjelkvåle, Dean S. Jeffries, Jussi Vuorenmaa, Bill Keller, Jiri Kopácek and Josef Vesely

Onset of submarine debris flow deposition far from original giant landslide pp. 541-544

P. J. Talling, R. B. Wynn, D. G. Masson, M. Frenz, B. T. Cronin, R. Schiebel, A. M. Akhmetzhanov, S. Dallmeier-Tiessen, S. Benetti, P. P. E. Weaver, A. Georgiopoulou, C. Zühlsdorff and L. A. Amy

Enhanced biological carbon consumption in a high CO2 ocean pp. 545-548

U. Riebesell, K. G. Schulz, R. G. J. Bellerby, M. Botros, P. Fritsche, M. Meyerhöfer, C. Neill, G. Nondal, A. Oschlies, J. Wohlers and E. Zöllner

Phase-contrast X-ray microtomography links Cretaceous seeds with Gnetales and Bennettitales pp. 549-552

Else Marie Friis, Peter R. Crane, Kaj Raunsgaard Pedersen, Stefan Bengtson, Philip C. J. Donoghue, Guido W. Grimm and Marco Stampanoni

An antidepressant that extends lifespan in adult Caenorhabditis elegans pp. 553-556

Michael Petrascheck, Xiaolan Ye and Linda B. Buck

Social evaluation by preverbal infants pp. 557-559

J. Kiley Hamlin, Karen Wynn and Paul Bloom

Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite pp. 560-565

Falk Warnecke, Peter Luginbühl, Natalia Ivanova, Majid Ghassemian, Toby H. Richardson, Justin T. Stege, Michelle Cayouette, Alice C. McHardy, Gordana Djordjevic, Nahla Aboushadi, Rotem Sorek, Susannah G. Tringe, Mircea Podar, Hector Garcia Martin, Victor Kunin, Daniel Dalevi, Julita Madejska, Edward Kirton, Darren Platt, Ernest Szeto, Asaf Salamov, Kerrie Barry, Natalia Mikhailova, Nikos C. Kyrpides, Eric G. Matson, Elizabeth A. Ottesen, Xinning Zhang, Myriam Hernández, Catalina Murillo, Luis G. Acosta, Isidore Rigoutsos, Giselle Tamayo, Brian D. Green, Cathy Chang, Edward M. Rubin, Eric J. Mathur, Dan E. Robertson, Philip Hugenholtz and Jared R. Leadbetter

The inhibitory cytokine IL-35 contributes to regulatory T-cell function pp. 566-569

Lauren W. Collison, Creg J. Workman, Timothy T. Kuo, Kelli Boyd, Yao Wang, Kate M. Vignali, Richard Cross, David Sehy, Richard S. Blumberg and Dario A. A. Vignali

A SNARE–adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles pp. 570-574

Sharon E. Miller, Brett M. Collins, Airlie J. McCoy, Margaret S. Robinson and David J. Owen

Identification of a mechanism of photoprotective energy dissipation in higher plants pp. 575-578

Alexander V. Ruban, Rudi Berera, Cristian Ilioaia, Ivo H. M. van Stokkum, John T. M. Kennis, Andrew A. Pascal, Herbert van Amerongen, Bruno Robert, Peter Horton and Rienk van Grondelle

Prospects pp. 579-579

Gene Russo

Indian biotech's bumpy road pp. 580-581

Paroma Basu

Susan Avery, president and director, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts pp. 582-582

Virginia Gewin

Grand designs pp. 582-582

Hannah Hoag

Leaving science research pp. 582-582

Peter Jordan

Dating for the wired generation pp. 584-584

Stephen Gaskell

2007, volume 450, articles 7168

Anti-correlation of summer/winter monsoons? pp. E7-E8

Zhang De’er and Longhua Lu

Yancheva et al. reply pp. E8-E9

Gergana Yancheva, Norbert R. Nowaczyk, Jens Mingram, Peter Dulski, Georg Schettler, Jörg F. W. Negendank, Jiaqi Liu, Daniel M. Sigman, Larry C. Peterson and Gerald H. Haug

Record of winter monsoon strength pp. E10-E11

Houyun Zhou, Huazheng Guan and Baoquan Chi

Yancheva et al. reply pp. E11-E11

Gergana Yancheva, Norbert R. Nowaczyk, Jens Mingram, Peter Dulski, Georg Schettler, Jörg F. W. Negendank, Jiaqi Liu, Daniel M. Sigman, Larry C. Peterson and Gerald H. Haug

Journal club pp. 323-323

Clive R. Bagshaw

Pakistan's universities take up protest pp. 324-325

Ehsan Masood

HIV vaccine may raise risk pp. 325-325

Heidi Ledford

The price of power pp. 326-326

Jeff Tollefson

$article.title pp. 327-327

Jeff Tollefson

Panel negotiates climate 'synthesis report' pp. 327-327

Jeff Tollefson

Snapshot: Light relief pp. 329-329

Nick Thomas

Brain waves reveal intensity of pain pp. 329-329

Kerri Smith

Light wormholes could wire space invisibly pp. 330-331

Philip Ball

Political climate pp. 333-333

David Goldston

Worth its weight in platinum pp. 334-335

Jeff Tollefson

Market watch pp. 335-335

Quirin Schiermeier

Climate politics: Showdown in a sunburnt country pp. 336-338

Stephen Pincock

Climate politics: Beyond Bush pp. 340-341

Jeff Tollefson

Climate politics: The first cut pp. 342-344

Jeff Tollefson

Climate politics: What every president should know pp. 345-345

Richard A. Muller

Independent evidence backs call for a badger cull pp. 346-346

David King

Kyoto: talks must include key aspects of science pp. 346-346

Aynsley Kellow

Kyoto: no time to rearrange deckchairs on the Titanic pp. 346-346

John Schellnhuber

Who has the ear of the president? pp. 347-348

Roger Pielke

A sixth mass extinction? pp. 349-349

Chris D. Thomas

Prescient marine champion pp. 350-350

Ken Collins

Human distilleries pp. 350-351

Robert P. Crease

Blurring our edges pp. 351-352

Judy Illes

Archimedes' secrets revealed pp. 352-353

Brian Clegg

The liquid of life pp. 353-353

Josie Glausiusz

Use the calm between the storms pp. 354-354

Steve Sparks

A receptor unlocked pp. 355-356

Stephen R. Sprang

Isotopic lunacy pp. 356-357

Alex N. Halliday

Reversing the 'irreversible' pp. 357-359

Richard S. Jones

Quick burial at sea pp. 360-361

Caroline A. Masiello

Pathogen drop-kick pp. 361-362

Suzanne Pfeffer

Kittens catch phase pp. 362-363

Jonathan P. Dowling

Legionella pneumophila proteins that regulate Rab1 membrane cycling pp. 365-369

Alyssa Ingmundson, Anna Delprato, David G. Lambright and Craig R. Roy

Portability of paddle motif function and pharmacology in voltage sensors pp. 370-375

AbdulRasheed A. Alabi, Maria Isabel Bahamonde, Hoi Jong Jung, Jae Il Kim and Kenton J. Swartz

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment pp. 376-382

Stephen B. Long, Xiao Tao, Ernest B. Campbell and Roderick MacKinnon

Crystal structure of the human β2 adrenergic G-protein-coupled receptor pp. 383-387

Søren G. F. Rasmussen, Hee-Jung Choi, Daniel M. Rosenbaum, Tong Sun Kobilka, Foon Sun Thian, Patricia C. Edwards, Manfred Burghammer, Venkata R. P. Ratnala, Ruslan Sanishvili, Robert F. Fischetti, Gebhard F. X. Schertler, William I. Weis and Brian K. Kobilka

A runaway collision in a young star cluster as the origin of the brightest supernova pp. 388-389

Simon F. Portegies Zwart and Edward P. J. van den Heuvel

Pulsational pair instability as an explanation for the most luminous supernovae pp. 390-392

S. E. Woosley, S. Blinnikov and Alexander Heger

Entanglement-free Heisenberg-limited phase estimation pp. 393-396

B. L. Higgins, D. W. Berry, S. D. Bartlett, H. M. Wiseman and G. J. Pryde

‘Trapped rainbow’ storage of light in metamaterials pp. 397-401

Kosmas L. Tsakmakidis, Allan D. Boardman and Ortwin Hess

Generation of single optical plasmons in metallic nanowires coupled to quantum dots pp. 402-406

A. V. Akimov, A. Mukherjee, C. L. Yu, D. E. Chang, A. S. Zibrov, P. R. Hemmer, H. Park and M. D. Lukin

Efficient organic carbon burial in the Bengal fan sustained by the Himalayan erosional system pp. 407-410

Valier Galy, Christian France-Lanord, Olivier Beyssac, Pierre Faure, Hermann Kudrass and Fabien Palhol

Cooperation and conflict in quorum-sensing bacterial populations pp. 411-414

Stephen P. Diggle, Ashleigh S. Griffin, Genevieve S. Campbell and Stuart A. West

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron pp. 415-419

Kristen Jepsen, Derek Solum, Tianyuan Zhou, Robert J. McEvilly, Hyun-Jung Kim, Christopher K. Glass, Ola Hermanson and Michael G. Rosenfeld

Neural substrates of awakening probed with optogenetic control of hypocretin neurons pp. 420-424

Antoine R. Adamantidis, Feng Zhang, Alexander M. Aravanis, Karl Deisseroth and Luis de Lecea

A synaptic memory trace for cortical receptive field plasticity pp. 425-429

Robert C. Froemke, Michael M. Merzenich and Christoph E. Schreiner

BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module pp. 430-434

Daeho Park, Annie-Carole Tosello-Trampont, Michael R. Elliott, Mingjian Lu, Lisa B. Haney, Zhong Ma, Alexander L. Klibanov, James W. Mandell and Kodi S. Ravichandran

Identification of Tim4 as a phosphatidylserine receptor pp. 435-439

Masanori Miyanishi, Kazutoshi Tada, Masato Koike, Yasuo Uchiyama, Toshio Kitamura and Shigekazu Nagata

SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation pp. 440-444

Alejandro Vaquero, Michael Scher, Hediye Erdjument-Bromage, Paul Tempst, Lourdes Serrano and Danny Reinberg

Molecular basis of RNA-dependent RNA polymerase II activity pp. 445-449

Elisabeth Lehmann, Florian Brueckner and Patrick Cramer

Erratum: Positive darwinian selection at the imprinted MEDEA locus in plants pp. 450-450

Charles Spillane, Karl J. Schmid, Sylvia Laoueillé-Duprat, Stéphane Pien, Juan-Miguel Escobar-Restrepo, Célia Baroux, Valeria Gagliardini, Damian R. Page, Kenneth H. Wolfe and Ueli Grossniklaus

Prospects pp. 451-451

Gene Russo

Allowing an élite pp. 452-453

Quirin Schiermeier

A better mousetrap pp. 456-456

Mike Resnick

2007, volume 450, articles 7167

Maternal nodal and zebrafish embryogenesis pp. E1-E2

James T. Bennett, Heather L. Stickney, Wen-Yee Choi, Brian Ciruna, William S. Talbot and Alexander F. Schier

Gore et al. reply pp. E2-E4

Aniket V. Gore, Albert Cheong, Patrick C. Gilligan and Karuna Sampath

Evolution of animal personalities pp. E5-E5

Richard McElreath, Barney Luttbeg, Sean P. Fogarty, Tomas Brodin and Andrew Sih

Wolf et al. reply pp. E5-E6

Max Wolf, G. Sander van Doorn, Olof Leimar and Franz J. Weissing

Journal club pp. 139-139

Brian J. Enquist

Attack of the genomes pp. 142-143

Heidi Ledford

Poor follow-up hampers malaria projects pp. 144-145

Declan Butler

Committee releases shortlist of Mars landing sites pp. 145-145

Oliver Morton

Peering into the heart of a black hole pp. 147-147

Philip Ball

Carbon tax lite pp. 151-151

Geoff Brumfiel

Conservation priorities: What to let go pp. 152-155

Emma Marris

Energy: To catch a wave pp. 156-159

Ewen Callaway

Time: research necessities make it hard to keep track pp. 161-161

Robert J. O'Connell

Time: accounting problems caused by Caltech system pp. 161-161

Robert D. McKeown

Turkish science suffers as government vies with law pp. 161-161

A. M. Celâl Sengör

Explorers' challenge sunk by Arctic warming pp. 161-161

A. J. (Tom) van Loon

Rules of engagement pp. 163-164

Patrick L. Taylor

Benchmarks for ageing studies pp. 165-167

Linda Partridge and David Gems

The twentieth century in a nutshell pp. 169-169

Colin Tudge

Dover trial documentary screens pp. 170-170

Adam Rutherford

Comparing modes of inquiry pp. 171-171

Carlos Martínez del Rio

Dance of the forest pp. 172-172

Michael Hopkin

Demonic deeds in symbiotic art pp. 172-172

Colin Martin

Time to pick the fly's brain pp. 173-173

Claude Desplan

A timely harvest pp. 174-174

Pierre-Benoit Joly and Arie Rip

Reality check pp. 175-176

Liesbeth Venema

Protein predictions pp. 176-177

Eleanor J. Dodson

Magnetic blue pp. 177-178

Jeroen van den Brink and Alberto F. Morpurgo

A twist on periodicity at Saturn pp. 178-179

Margaret Galland Kivelson

Nets versus nature pp. 179-180

David O. Conover

The power of blood pp. 180-181

Paige Snider and Simon J. Conway

Wolfgang K. H. Panofsky (1919–2007) pp. 182-182

Sidney D. Drell

Genome labours bear fruit pp. 183-183

Chris Gunter, Francesca Cesari, Deepa Nath, I-Han Chou, Alex Eccleston and Ritu Dhand

Come fly with us pp. 184-185

Ewan Birney

Drosophila and the genetics of the internal milieu pp. 186-188

Pierre Leopold and Norbert Perrimon

Orchestrating size and shape during morphogenesis pp. 189-192

Thomas Lecuit and Loïc Le Goff

Into the mind of a fly pp. 193-197

Leslie B. Vosshall

Imaging Drosophila gene activation and polymerase pausing in vivo pp. 198-202

John T. Lis

Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures pp. 219-232

Alexander Stark, Michael F. Lin, Pouya Kheradpour, Jakob S. Pedersen, Leopold Parts, Joseph W. Carlson, Madeline A. Crosby, Matthew D. Rasmussen, Sushmita Roy, Ameya N. Deoras, J. Graham Ruby, Julius Brennecke, Emily Hodges, Angie S. Hinrichs, Anat Caspi, Benedict Paten, Seung-Won Park, Mira V. Han, Morgan L. Maeder, Benjamin J. Polansky, Bryanne E. Robson, Stein Aerts, Jacques van Helden, Bassem Hassan, Donald G. Gilbert, Deborah A. Eastman, Michael Rice, Michael Weir, Matthew W. Hahn, Yongkyu Park, Colin N. Dewey, Lior Pachter, W. James Kent, David Haussler, Eric C. Lai, David P. Bartel, Gregory J. Hannon, Thomas C. Kaufman, Michael B. Eisen, Andrew G. Clark, Douglas Smith, Susan E. Celniker, William M. Gelbart and Manolis Kellis

Constraint and turnover in sex-biased gene expression in the genus Drosophila pp. 233-237

Yu Zhang, David Sturgill, Michael Parisi, Sudhir Kumar and Brian Oliver

Demasculinization of X chromosomes in the Drosophila genus pp. 238-241

David Sturgill, Yu Zhang, Michael Parisi and Brian Oliver

The remarkable metal-catalysed olefin metathesis reaction pp. 243-251

Amir H. Hoveyda and Adil R. Zhugralin

Hedgehog regulates smoothened activity by inducing a conformational switch pp. 252-258

Yun Zhao, Chao Tong and Jin Jiang

High-resolution structure prediction and the crystallographic phase problem pp. 259-264

Bin Qian, Srivatsan Raman, Rhiju Das, Philip Bradley, Airlie J. McCoy, Randy J. Read and David Baker

Modulation of Saturn’s radio clock by solar wind speed pp. 265-267

Philippe Zarka, Laurent Lamy, Baptiste Cecconi, Renée Prangé and Helmut O. Rucker

Cavity QED with a Bose–Einstein condensate pp. 268-271

Ferdinand Brennecke, Tobias Donner, Stephan Ritter, Thomas Bourdel, Michael Köhl and Tilman Esslinger

Strong atom–field coupling for Bose–Einstein condensates in an optical cavity on a chip pp. 272-276

Yves Colombe, Tilo Steinmetz, Guilhem Dubois, Felix Linke, David Hunger and Jakob Reichel

Stability of organic carbon in deep soil layers controlled by fresh carbon supply pp. 277-280

Sébastien Fontaine, Sébastien Barot, Pierre Barré, Nadia Bdioui, Bruno Mary and Cornelia Rumpel

Detection of stratospheric ozone intrusions by windprofiler radars pp. 281-284

W. K. Hocking, T. Carey-Smith, D. W. Tarasick, P. S. Argall, K. Strong, Y. Rochon, I. Zawadzki and P. A. Taylor

Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch pp. 285-288

Kenta Yashiro, Hidetaka Shiratori and Hiroshi Hamada

An essential role for a CD36-related receptor in pheromone detection in Drosophila pp. 289-293

Richard Benton, Kirsten S. Vannice and Leslie B. Vosshall

Drosophila hygrosensation requires the TRP channels water witch and nanchung pp. 294-298

Lei Liu, Yuhong Li, Runping Wang, Chong Yin, Qian Dong, Huey Hing, Changsoo Kim and Michael J. Welsh

Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA pp. 299-303

Di Yu, Andy Hee-Meng Tan, Xin Hu, Vicki Athanasopoulos, Nicholas Simpson, Diego G. Silva, Andreas Hutloff, Keith M. Giles, Peter J. Leedman, Kong Peng Lam, Christopher C. Goodnow and Carola G. Vinuesa

An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster pp. 304-308

Hang Yin and Haifan Lin

JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes pp. 309-313

David Frescas, Daniele Guardavaccaro, Florian Bassermann, Ryo Koyama-Nasu and Michele Pagano

Prospects pp. 315-315

Gene Russo

Alan Bernstein, executive director, Global HIV Vaccine Enterprise, Seattle, Washington pp. 316-316

Virginia Gewin

Latin American challenges pp. 316-316

Fernanda De Felice

Meet my lab minion pp. 316-316

Chris Rowan

A hand and honour pp. 318-318

Brenda Cooper

2007, volume 450, articles 7166

Journal club pp. 5-5

James E. Ferrell

Model behaviour pp. 6-7

Alison Abbott

Sponsor hunt divides geosciences union pp. 9-9

Quirin Schiermeier

Personalized genomes go mainstream pp. 11-11

Erika Check Hayden

China blasts off on lunar exploration pp. 12-12

Eric Hand

India digs deep to build neutrino lab pp. 13-13

K. S. Jayaraman

Mixed scores for European research pp. 16-17

Andrea Chipman

Palaeontology: Tunnel vision pp. 18-20

Alison Abbott

Neuroscience: A gut feeling pp. 21-23

Ishani Ganguli

Philanthropy: A country without alms pp. 24-25

David Cyranoski

Sea-ice decline due to more than warming alone pp. 27-27

Julia Slingo and Rowan Sutton

Ethics reviews can be centralized without delays pp. 27-27

Jeffrey Abrams and Jacquelyn Goldberg

Missing the mark on biomedical research pp. 27-27

David Korn and Stephen J. Heinig

Words of wisdom worth reading aloud pp. 27-27

Vanessa S. Solomon

Poetry in motion pp. 29-30

Patricia Churchland

Prions, pleasure and purple notes pp. 30-30

Chris McManus

Delving into the ancient brain pp. 31-32

Dean Falk

Space and time gift-wrapped pp. 32-32

Andrew Jaffe

Hidden depths spotted pp. 32-32

Emiliano Feresin

Technologies of humility pp. 33-33

Sheila Jasanoff

The worm turns pp. 35-36

Piali Sengupta

Aromatics with a twist pp. 36-37

Rainer Herges

Dynamic platforms pp. 37-39

Roger C. Hardie

First encounters pp. 40-41

Michael F. Shlesinger

Deadly special deliveries pp. 41-43

Nicholas J. Talbot

A fantasia on Kölliker's organ pp. 43-44

Ian D. Forsythe

Patterns of relative species abundance in rainforests and coral reefs pp. 45-49

Igor Volkov, Jayanth R. Banavar, Stephen P. Hubbell and Amos Maritan

The origin of spontaneous activity in the developing auditory system pp. 50-55

Nicolas X. Tritsch, Eunyoung Yi, Jonathan E. Gale, Elisabeth Glowatzki and Dwight E. Bergles

Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system pp. 56-62

Jean Livet, Tamily A. Weissman, Hyuno Kang, Ryan W. Draft, Ju Lu, Robyn A. Bennis, Joshua R. Sanes and Jeff W. Lichtman

Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans pp. 63-70

Sreekanth H. Chalasani, Nikos Chronis, Makoto Tsunozaki, Jesse M. Gray, Daniel Ramot, Miriam B. Goodman and Cornelia I. Bargmann

Circular polarimetry reveals helical magnetic fields in the young stellar object HH 135–136 pp. 71-73

Antonio Chrysostomou, Philip W. Lucas and James H. Hough

The rotating wind of the quasar PG 1700+518 pp. 74-76

S. Young, D. J. Axon, A. Robinson, J. H. Hough and J. E. Smith

First-passage times in complex scale-invariant media pp. 77-80

S. Condamin, O. Bénichou, V. Tejedor, R. Voituriez and J. Klafter

Abrupt onset of a second energy gap at the superconducting transition of underdoped Bi2212 pp. 81-84

W. S. Lee, I. M. Vishik, K. Tanaka, D. H. Lu, T. Sasagawa, N. Nagaosa, T. P. Devereaux, Z. Hussain and Z.-X. Shen

Radio-frequency scanning tunnelling microscopy pp. 85-88

U. Kemiktarak, T. Ndukum, K. C. Schwab and K. L. Ekinci

Fire as the dominant driver of central Canadian boreal forest carbon balance pp. 89-92

Ben Bond-Lamberty, Scott D. Peckham, Douglas E. Ahl and Stith T. Gower

Convergent dental adaptations in pseudo-tribosphenic and tribosphenic mammals pp. 93-97

Zhe-Xi Luo, Qiang Ji and Chong-Xi Yuan

Thresholds and the resilience of Caribbean coral reefs pp. 98-101

Peter J. Mumby, Alan Hastings and Helen J. Edwards

Neural mechanisms mediating optimism bias pp. 102-105

Tali Sharot, Alison M. Riccardi, Candace M. Raio and Elizabeth A. Phelps

PYY modulation of cortical and hypothalamic brain areas predicts feeding behaviour in humans pp. 106-109

Rachel L. Batterham, Dominic H. Ffytche, J. Miranda Rosenthal, Fernando O. Zelaya, Gareth J. Barker, Dominic J. Withers and Steven C. R. Williams

Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells pp. 110-114

Tobias Junt, E. Ashley Moseman, Matteo Iannacone, Steffen Massberg, Philipp A. Lang, Marianne Boes, Katja Fink, Sarah E. Henrickson, Dmitry M. Shayakhmetov, Nelson C. Di Paolo, Nico van Rooijen, Thorsten R. Mempel, Sean P. Whelan and Ulrich H. von Andrian

A translocation signal for delivery of oomycete effector proteins into host plant cells pp. 115-118

Stephen C. Whisson, Petra C. Boevink, Lucy Moleleki, Anna O. Avrova, Juan G. Morales, Eleanor M. Gilroy, Miles R. Armstrong, Severine Grouffaud, Pieter van West, Sean Chapman, Ingo Hein, Ian K. Toth, Leighton Pritchard and Paul R. J. Birch

Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis pp. 119-123

Yuki Okada, Greg Scott, Manas K. Ray, Yuji Mishina and Yi Zhang

Probing the chemistry of thioredoxin catalysis with force pp. 124-127

Arun P. Wiita, Raul Perez-Jimenez, Kirstin A. Walther, Frauke Gräter, B. J. Berne, Arne Holmgren, Jose M. Sanchez-Ruiz and Julio M. Fernandez

Erratum: Insight foreword: Food and the future pp. 128-128

H. Gee

Prospects pp. 129-129

Gene Russo

Brain storm pp. 130-131

Paul Smaglik

Vasilis Ntziachristos, director, Institute for Biological and Medical Imaging, GSF, Neuherberg, Germany pp. 132-132

Virginia Gewin

Brain work pp. 132-132

Paul Smaglik

Corporate America pp. 132-132

Moira Sheehan

A sudden absence of bees pp. 134-134

Nick Mamatas