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2021, volume 595, articles 7869

Remember Ebola: stop mass COVID deaths in Africa pp. 627-627

Mosoka Fallah

The US is boosting funding for research monkeys in the wake of COVID pp. 633-634

Nidhi Subbaraman

DeepMind’s AI predicts structures for a vast trove of proteins pp. 635-635

Ewen Callaway

Massive DNA ‘Borg’ structures perplex scientists pp. 636-636

Amber Dance

China launches world’s largest carbon market: but is it ambitious enough? pp. 637-637

Bianca Nogrady

Should children get COVID vaccines? What the science says pp. 638-639

Heidi Ledford

Deaths from COVID ‘incredibly rare’ among children pp. 639-639

Heidi Ledford

How the coronavirus infects cells — and why Delta is so dangerous pp. 640-644

Megan Scudellari

Richard R. Ernst (1933—2021) pp. 645-645

Kurt Wüthrich

Biodiversity needs every tool in the box: use OECMs pp. 646-649

Georgina G. Gurney, Emily S. Darling, Gabby N. Ahmadia, Vera N. Agostini, Natalie C. Ban, Jessica Blythe, Joachim Claudet, Graham Epstein, Estradivari, Amber Himes-Cornell, Harry D. Jonas, Derek Armitage, Stuart J. Campbell, Courtney Cox, Whitney. R. Friedman, David Gill, Peni Lestari, Sangeeta Mangubhai, Elizabeth McLeod, Nyawira A. Muthiga, Josheena Naggea, Ravaka Ranaivoson, Amelia Wenger, Irfan Yulianto and Stacy D. Jupiter

Scientists — reach across the aisle, Republicans could be back soon pp. 650-650

Imran Khan

Europe’s reformed agricultural policy disappoints pp. 650-650

Jeroen J. L. Candel, Sebastian Lakner and Guy Pe’er

Global climate models do not need more behavioural science pp. 650-650

M. Granger Morgan and Hadi Dowlatabadi

Peru to punish bending of clinical-trial rules pp. 650-650

Cesar Cabezas-Sanchez, Yamilee Hurtado-Roca and Victor Suárez-Moreno

A protective signal between the brain’s supporting cells in Alzheimer’s disease pp. 651-652

Jerika J. Barron and Anna V. Molofsky

Direct installation of boron groups offers boost to medicinal chemistry pp. 652-653

Christine M. Le

Sperm CatSper ion channel swims into sharper focus pp. 654-655

David E. Clapham and Raymond E. Hulse

Earthquakes triggered by underground fluid injection modelled for a tectonically active oil field pp. 655-656

Mirko van der Baan

Light bending and X-ray echoes from behind a supermassive black hole pp. 657-660

D. R. Wilkins, L. C. Gallo, E. Costantini, W. N. Brandt and R. D. Blandford

Incoherent transport across the strange-metal regime of overdoped cuprates pp. 661-666

J. Ayres, M. Berben, M. Čulo, Y.-T. Hsu, E. Heumen, Y. Huang, J. Zaanen, T. Kondo, T. Takeuchi, J. R. Cooper, C. Putzke, S. Friedemann, A. Carrington and N. E. Hussey

Linear-in temperature resistivity from an isotropic Planckian scattering rate pp. 667-672

Gaël Grissonnanche, Yawen Fang, Anaëlle Legros, Simon Verret, Francis Laliberté, Clément Collignon, Jianshi Zhou, David Graf, Paul A. Goddard, Louis Taillefer and B. J. Ramshaw

Spectroscopic evidence for a gold-coloured metallic water solution pp. 673-676

Philip E. Mason, H. Christian Schewe, Tillmann Buttersack, Vojtech Kostal, Marco Vitek, Ryan S. McMullen, Hebatallah Ali, Florian Trinter, Chin Lee, Daniel M. Neumark, Stephan Thürmer, Robert Seidel, Bernd Winter, Stephen E. Bradforth and Pavel Jungwirth

A radical approach for the selective C–H borylation of azines pp. 677-683

Ji Hye Kim, Timothée Constantin, Marco Simonetti, Josep Llaveria, Nadeem S. Sheikh and Daniele Leonori

A process-based approach to understanding and managing triggered seismicity pp. 684-689

Bradford H. Hager, James Dieterich, Cliff Frohlich, Ruben Juanes, Stefano Mantica, John H. Shaw, Francesca Bottazzi, Federica Caresani, David Castineira, Alberto Cominelli, Marco Meda, Lorenzo Osculati, Stefania Petroselli and Andreas Plesch

Dynamical prefrontal population coding during defensive behaviours pp. 690-694

Daniel Jercog, Nanci Winke, Kibong Sung, Mario Martin Fernandez, Claire Francioni, Domitille Rajot, Julien Courtin, Fabrice Chaudun, Pablo E. Jercog, Stephane Valerio and Cyril Herry

Food cue regulation of AGRP hunger neurons guides learning pp. 695-700

Janet Berrios, Chia Li, Joseph C. Madara, Alastair S. Garfield, Jennifer S. Steger, Michael J. Krashes and Bradford B. Lowell

Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease pp. 701-706

Cameron S. McAlpine, Joseph Park, Ana Griciuc, Eunhee Kim, Se Hoon Choi, Yoshiko Iwamoto, Máté G. Kiss, Kathleen A. Christie, Claudio Vinegoni, Wolfram C. Poller, John E. Mindur, Christopher T. Chan, Shun He, Henrike Janssen, Lai Ping Wong, Jeffrey Downey, Sumnima Singh, Atsushi Anzai, Florian Kahles, Mehdi Jorfi, Paolo Fumene Feruglio, Ruslan I. Sadreyev, Ralph Weissleder, Benjamin P. Kleinstiver, Matthias Nahrendorf, Rudolph E. Tanzi and Filip K. Swirski

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020 pp. 707-712

Emma B. Hodcroft, Moira Zuber, Sarah Nadeau, Timothy G. Vaughan, Katharine H. D. Crawford, Christian L. Althaus, Martina L. Reichmuth, John E. Bowen, Alexandra C. Walls, Davide Corti, Jesse D. Bloom, David Veesler, David Mateo, Alberto Hernando, Iñaki Comas, Fernando González-Candelas, Tanja Stadler and Richard A. Neher

Untangling introductions and persistence in COVID-19 resurgence in Europe pp. 713-717

Philippe Lemey, Nick Ruktanonchai, Samuel L. Hong, Vittoria Colizza, Chiara Poletto, Frederik Van den Broeck, Mandev S. Gill, Xiang Ji, Anthony Levasseur, Bas B. Oude Munnink, Marion Koopmans, Adam Sadilek, Shengjie Lai, Andrew J. Tatem, Guy Baele, Marc A. Suchard and Simon Dellicour

Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants pp. 718-723

Zhiqiang Ku, Xuping Xie, Paul R. Hinton, Xinli Liu, Xiaohua Ye, Antonio E. Muruato, Dean C. Ng, Sujit Biswas, Jing Zou, Yang Liu, Deepal Pandya, Vineet D. Menachery, Sachi Rahman, Yu-An Cao, Hui Deng, Wei Xiong, Kevin B. Carlin, Junquan Liu, Hang Su, Elizabeth J. Haanes, Bruce A. Keyt, Ningyan Zhang, Stephen F. Carroll, Pei-Yong Shi and Zhiqiang An

Metabolic control of TFH cells and humoral immunity by phosphatidylethanolamine pp. 724-729

Guotong Fu, Clifford S. Guy, Nicole M. Chapman, Gustavo Palacios, Jun Wei, Peipei Zhou, Lingyun Long, Yong-Dong Wang, Chenxi Qian, Yogesh Dhungana, Hongling Huang, Anil Kc, Hao Shi, Sherri Rankin, Scott A. Brown, Amanda Johnson, Randall Wakefield, Camenzind G. Robinson, Xueyan Liu, Anthony Sheyn, Jiyang Yu, Suzanne Jackowski and Hongbo Chi

EGFR activation limits the response of liver cancer to lenvatinib pp. 730-734

Haojie Jin, Yaoping Shi, Yuanyuan Lv, Shengxian Yuan, Christel F. A. Ramirez, Cor Lieftink, Liqin Wang, Siying Wang, Cun Wang, Matheus Henrique Dias, Fleur Jochems, Yuan Yang, Astrid Bosma, E. Marielle Hijmans, Marnix H. P. Groot, Serena Vegna, Dan Cui, Yangyang Zhou, Jing Ling, Hui Wang, Yuchen Guo, Xingling Zheng, Nikita Isima, Haiqiu Wu, Chong Sun, Roderick L. Beijersbergen, Leila Akkari, Weiping Zhou, Bo Zhai, Wenxin Qin and René Bernards

Enhancer release and retargeting activates disease-susceptibility genes pp. 735-740

Soohwan Oh, Jiaofang Shao, Joydeep Mitra, Feng Xiong, Matteo D’Antonio, Ruoyu Wang, Ivan Garcia-Bassets, Qi Ma, Xiaoyu Zhu, Joo-Hyung Lee, Sreejith J. Nair, Feng Yang, Kenneth Ohgi, Kelly A. Frazer, Zhengdong D. Zhang, Wenbo Li and Michael G. Rosenfeld

Structural basis of early translocation events on the ribosome pp. 741-745

Emily J. Rundlet, Mikael Holm, Magdalena Schacherl, S. Kundhavai Natchiar, Roger B. Altman, Christian M. T. Spahn, Alexander G. Myasnikov and Scott C. Blanchard

Structure of a mammalian sperm cation channel complex pp. 746-750

Shiyi Lin, Meng Ke, Yuqi Zhang, Zhen Yan and Jianping Wu

Why science needs a new reward and recognition system pp. 751-753

Edyta Swider-Cios, Katalin Solymosi and Mangala Srinivas

Chemical modelling with a sense of touch pp. 756-756

Kendall Powell

2021, volume 595, articles 7868

Publisher Correction: A 20-year retrospective review of global aquaculture pp. E36-E36

Rosamond L. Naylor, Ronald W. Hardy, Alejandro H. Buschmann, Simon R. Bush, Ling Cao, Dane H. Klinger, David C. Little, Jane Lubchenco, Sandra E. Shumway and Max Troell

Why England’s COVID ‘freedom day’ alarms researchers pp. 479-480

Philip Ball

‘Pregnant’ male rat study kindles bioethical debate in China pp. 481-481

Smriti Mallapaty

Long COVID and kids: scientists race to find answers pp. 482-483

Dyani Lewis

The rise of ‘ARPA-everything’ and what it means for science pp. 483-484

Jeff Tollefson

COVID and the brain: researchers zero in on how damage occurs pp. 484-485

Michael Marshall

Gun violence is surging — researchers finally have the money to ask why pp. 486-488

Nidhi Subbaraman

Richard C. Lewontin (1929–2021) pp. 489-489

Michael R. Dietrich

Huge gaps in detection networks plague emissions monitoring pp. 491-493

Ray F. Weiss, A. R. Ravishankara and Paul A. Newman

Solar geoengineering research needs formal global debate pp. 494-494

Janos Pasztor

Andes foothills protected by carbon-offset fund pp. 494-494

Evert Thomas, Marleni Ramirez, Lily Rodriguez and Manuel Glave

ISSCR guidelines uphold human right to science for benefit of all pp. 494-494

Zubin Master, Robin Lovell-Badge and Bartha Knoppers

Six years as university rector changed how I do genetics pp. 494-494

Giuseppe Novelli

Superconductivity in a graphene system survives a strong magnetic field pp. 495-496

Yi-Ting Hsu

A step closer to compact X-ray lasers pp. 496-497

Luca Giannessi

Fluid flow through a deep-sea sponge could inspire engineering designs pp. 497-498

Laura A. Miller

Receptor–enzyme complex structures show how receptors start to switch off pp. 499-500

Vsevolod V. Gurevich and Eugenia V. Gurevich

A multilayered immune system through the lens of unconventional T cells pp. 501-510

Toufic Mayassi, Luis B. Barreiro, Jamie Rossjohn and Bana Jabri

The nightside cloud-top circulation of the atmosphere of Venus pp. 511-515

Kiichi Fukuya, Takeshi Imamura, Makoto Taguchi, Tetsuya Fukuhara, Toru Kouyama, Takeshi Horinouchi, Javier Peralta, Masahiko Futaguchi, Takeru Yamada, Takao M. Sato, Atsushi Yamazaki, Shin-ya Murakami, Takehiko Satoh, Masahiro Takagi and Masato Nakamura

Free-electron lasing at 27 nanometres based on a laser wakefield accelerator pp. 516-520

Wentao Wang, Ke Feng, Lintong Ke, Changhai Yu, Yi Xu, Rong Qi, Yu Chen, Zhiyong Qin, Zhijun Zhang, Ming Fang, Jiaqi Liu, Kangnan Jiang, Hao Wang, Cheng Wang, Xiaojun Yang, Fenxiang Wu, Yuxin Leng, Jiansheng Liu, Ruxin Li and Zhizhan Xu

Layer Hall effect in a 2D topological axion antiferromagnet pp. 521-525

Anyuan Gao, Yu-Fei Liu, Chaowei Hu, Jian-Xiang Qiu, Christian Tzschaschel, Barun Ghosh, Sheng-Chin Ho, Damien Bérubé, Rui Chen, Haipeng Sun, Zhaowei Zhang, Xin-Yue Zhang, Yu-Xuan Wang, Naizhou Wang, Zumeng Huang, Claudia Felser, Amit Agarwal, Thomas Ding, Hung-Ju Tien, Austin Akey, Jules Gardener, Bahadur Singh, Kenji Watanabe, Takashi Taniguchi, Kenneth S. Burch, David C. Bell, Brian B. Zhou, Weibo Gao, Hai-Zhou Lu, Arun Bansil, Hsin Lin, Tay-Rong Chang, Liang Fu, Qiong Ma, Ni Ni and Su-Yang Xu

Pauli-limit violation and re-entrant superconductivity in moiré graphene pp. 526-531

Yuan Cao, Jeong Min Park, Kenji Watanabe, Takashi Taniguchi and Pablo Jarillo-Herrero

A natively flexible 32-bit Arm microprocessor pp. 532-536

John Biggs, James Myers, Jedrzej Kufel, Emre Ozer, Simon Craske, Antony Sou, Catherine Ramsdale, Ken Williamson, Richard Price and Scott White

Extreme flow simulations reveal skeletal adaptations of deep-sea sponges pp. 537-541

Giacomo Falcucci, Giorgio Amati, Pierluigi Fanelli, Vesselin K. Krastev, Giovanni Polverino, Maurizio Porfiri and Sauro Succi

Orthogonal-array dynamic molecular sieving of propylene/propane mixtures pp. 542-548

Heng Zeng, Mo Xie, Ting Wang, Rong-Jia Wei, Xiao-Jing Xie, Yifang Zhao, Weigang Lu and Dan Li

Sexual arousal gates visual processing during Drosophila courtship pp. 549-553

Tom Hindmarsh Sten, Rufei Li, Adriane Otopalik and Vanessa Ruta

Molecular logic of cellular diversification in the mouse cerebral cortex pp. 554-559

Daniela J. Di Bella, Ehsan Habibi, Robert R. Stickels, Gabriele Scalia, Juliana Brown, Payman Yadollahpour, Sung Min Yang, Catherine Abbate, Tommaso Biancalani, Evan Z. Macosko, Fei Chen, Aviv Regev and Paola Arlotta

Acetate differentially regulates IgA reactivity to commensal bacteria pp. 560-564

Tadashi Takeuchi, Eiji Miyauchi, Takashi Kanaya, Tamotsu Kato, Yumiko Nakanishi, Takashi Watanabe, Toshimori Kitami, Takashi Taida, Takaharu Sasaki, Hiroki Negishi, Shu Shimamoto, Akinobu Matsuyama, Ikuo Kimura, Ifor R. Williams, Osamu Ohara and Hiroshi Ohno

Dysregulation of brain and choroid plexus cell types in severe COVID-19 pp. 565-571

Andrew C. Yang, Fabian Kern, Patricia M. Losada, Maayan R. Agam, Christina A. Maat, Georges P. Schmartz, Tobias Fehlmann, Julian A. Stein, Nicholas Schaum, Davis P. Lee, Kruti Calcuttawala, Ryan T. Vest, Daniela Berdnik, Nannan Lu, Oliver Hahn, David Gate, M. Windy McNerney, Divya Channappa, Inma Cobos, Nicole Ludwig, Walter J. Schulz-Schaeffer, Andreas Keller and Tony Wyss-Coray

BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans pp. 572-577

Ugur Sahin, Alexander Muik, Isabel Vogler, Evelyna Derhovanessian, Lena M. Kranz, Mathias Vormehr, Jasmin Quandt, Nicole Bidmon, Alexander Ulges, Alina Baum, Kristen E. Pascal, Daniel Maurus, Sebastian Brachtendorf, Verena Lörks, Julian Sikorski, Peter Koch, Rolf Hilker, Dirk Becker, Ann-Kathrin Eller, Jan Grützner, Manuel Tonigold, Carsten Boesler, Corinna Rosenbaum, Ludwig Heesen, Marie-Cristine Kühnle, Asaf Poran, Jesse Z. Dong, Ulrich Luxemburger, Alexandra Kemmer-Brück, David Langer, Martin Bexon, Stefanie Bolte, Tania Palanche, Armin Schultz, Sybille Baumann, Azita J. Mahiny, Gábor Boros, Jonas Reinholz, Gábor T. Szabó, Katalin Karikó, Pei-Yong Shi, Camila Fontes-Garfias, John L. Perez, Mark Cutler, David Cooper, Christos A. Kyratsous, Philip R. Dormitzer, Kathrin U. Jansen and Özlem Türeci

Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells pp. 578-584

María Casanova-Acebes, Erica Dalla, Andrew M. Leader, Jessica LeBerichel, Jovan Nikolic, Blanca M. Morales, Markus Brown, Christie Chang, Leanna Troncoso, Steven T. Chen, Ana Sastre-Perona, Matthew D. Park, Alexandra Tabachnikova, Maxime Dhainaut, Pauline Hamon, Barbara Maier, Catherine M. Sawai, Esperanza Agulló-Pascual, Markus Schober, Brian D. Brown, Boris Reizis, Thomas Marron, Ephraim Kenigsberg, Christine Moussion, Philippe Benaroch, Julio A. Aguirre-Ghiso and Miriam Merad

Clonal fitness inferred from time-series modelling of single-cell cancer genomes pp. 585-590

Sohrab Salehi, Farhia Kabeer, Nicholas Ceglia, Mirela Andronescu, Marc J. Williams, Kieran R. Campbell, Tehmina Masud, Beixi Wang, Justina Biele, Jazmine Brimhall, David Gee, Hakwoo Lee, Jerome Ting, Allen W. Zhang, Hoa Tran, Ciara O’Flanagan, Fatemeh Dorri, Nicole Rusk, Teresa Ruiz Algara, So Ra Lee, Brian Yu Chieh Cheng, Peter Eirew, Takako Kono, Jenifer Pham, Diljot Grewal, Daniel Lai, Richard Moore, Andrew J. Mungall, Marco A. Marra, Andrew McPherson, Alexandre Bouchard-Côté, Samuel Aparicio and Sohrab P. Shah

Phase separation drives aberrant chromatin looping and cancer development pp. 591-595

Jeong Hyun Ahn, Eric S. Davis, Timothy A. Daugird, Shuai Zhao, Ivana Yoseli Quiroga, Hidetaka Uryu, Jie Li, Aaron J. Storey, Yi-Hsuan Tsai, Daniel P. Keeley, Samuel G. Mackintosh, Ricky D. Edmondson, Stephanie D. Byrum, Ling Cai, Alan J. Tackett, Deyou Zheng, Wesley R. Legant, Douglas H. Phanstiel and Gang Greg Wang

A condensate-hardening drug blocks RSV replication in vivo pp. 596-599

Jennifer Risso-Ballester, Marie Galloux, Jingjing Cao, Ronan Goffic, Fortune Hontonnou, Aude Jobart-Malfait, Aurore Desquesnes, Svenja M. Sake, Sibylle Haid, Miaomiao Du, Xiumei Zhang, Huanyun Zhang, Zhaoguo Wang, Vincent Rincheval, Youming Zhang, Thomas Pietschmann, Jean-François Eléouët, Marie-Anne Rameix-Welti and Ralf Altmeyer

Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1 pp. 600-605

Qiuyan Chen, Manolo Plasencia, Zhuang Li, Somnath Mukherjee, Dhabaleswar Patra, Chun-Liang Chen, Thomas Klose, Xin-Qiu Yao, Anthony A. Kossiakoff, Leifu Chang, Philip C. Andrews and John J. G. Tesmer

cAMP binding to closed pacemaker ion channels is non-cooperative pp. 606-610

David S. White, Sandipan Chowdhury, Vinay Idikuda, Ruohan Zhang, Scott T. Retterer, Randall H. Goldsmith and Baron Chanda

The parenting penalties faced by scientist mothers pp. 611-613

Kendall Powell

Single-cell analysis enters the multiomics age pp. 614-616

Jeffrey M. Perkel

A monkey researcher fights to protect threatened and endangered primates pp. 618-618

Virginia Gewin

2021, volume 595, articles 7867

Autoimmune disease pp. S45-S45

Richard Hodson

Research round-up: autoimmune disease pp. S46-S47

Laura Vargas-Parada

How pandemics strengthen links between viruses and autoimmunity pp. S48-S50

Anthony King

Why autoimmunity is most common in women pp. S51-S53

Emily Sohn

Gut feeling yields evidence of microbial involvement in autoimmunity pp. S54-S55

Elizabeth Svoboda

Alopecia areata: why the battle isn’t over pp. S56-S56

Laura Vargas-Parada

Cracking the genetic code of autoimmune disease pp. S57-S59

Simon Makin

Creating T cells to guard against autoimmune disease pp. S60-S62

Eric Bender

Bioelectronic devices could treat autoimmune disease pp. S63-S63

Julianna Photopoulos

How stem cells could fix type 1 diabetes pp. S64-S66

Liam Drew

I critiqued my past papers on social media — here’s what I learnt pp. 333-333

Nicholas P. Holmes

Mounting evidence suggests Sputnik COVID vaccine is safe and effective pp. 339-340

Bianca Nogrady

The COVID pandemic’s lingering impact on clinical trials pp. 341-342

Heidi Ledford

COVID vaccines to reach poorest countries in 2023 — despite recent pledges pp. 342-343

T. V. Padma

Will COVID become a disease of the young? pp. 343-344

Smriti Mallapaty

Mix-and-match COVID vaccines: the case is growing, but questions remain pp. 344-345

Dyani Lewis

The quest to find genes that drive severe COVID pp. 346-348

Ewen Callaway

Racism is magnifying the deadly impact of rising city heat pp. 349-351

Alexandra Witze

Italy: scientists petition against biodynamic farming law pp. 352-352

Giorgio Parisi, Maria Pia Abbracchio, Gennaro Ciliberto, Massimo Tagliavini, Karin Metzlaff and Alan Schulman

Scale up rapid research autopsies for tissue immunology pp. 352-352

Stephen A. Rawlings, Antoine Chaillon, Davey Smith and Sara Gianella

Mental health: set up long-term cohort studies pp. 352-352

Ralf Buckley and Paula Brough

To build resilience, study complex systems pp. 352-352

Len Fisher

Italy: Forest harvesting is the opposite of green growth pp. 353-353

Roberto Cazzolla Gatti, Gianluca Piovesan and Alessandro Chiarucci

Pollution from hydrogen fuel could widen inequality pp. 353-353

Alastair Lewis

Africa: renewables infrastructure avoids stranded assets pp. 353-353

Zhanyun Wang and Miriam Diamond

Southeast Amazonia is no longer a carbon sink pp. 354-355

Scott Denning

Deciphering metabolism, one microbe at a time pp. 355-357

William F. Kindschuh and Tal Korem

Measurement-based system provides quantum control of nanoparticles pp. 357-358

Tania S. Monteiro

A long-term perspective on immunity to COVID pp. 359-360

Andreas Radbruch and Hyun-Dong Chang

Designing the next generation of proton-exchange membrane fuel cells pp. 361-369

Kui Jiao, Jin Xuan, Qing Du, Zhiming Bao, Biao Xie, Bowen Wang, Yan Zhao, Linhao Fan, Huizhi Wang, Zhongjun Hou, Sen Huo, Nigel P. Brandon, Yan Yin and Michael D. Guiver

The 13CO-rich atmosphere of a young accreting super-Jupiter pp. 370-372

Yapeng Zhang, Ignas A. G. Snellen, Alexander J. Bohn, Paul Mollière, Christian Ginski, H. Jens Hoeijmakers, Matthew A. Kenworthy, Eric E. Mamajek, Tiffany Meshkat, Maddalena Reggiani and Frans Snik

Real-time optimal quantum control of mechanical motion at room temperature pp. 373-377

Lorenzo Magrini, Philipp Rosenzweig, Constanze Bach, Andreas Deutschmann-Olek, Sebastian G. Hofer, Sungkun Hong, Nikolai Kiesel, Andreas Kugi and Markus Aspelmeyer

Quantum control of a nanoparticle optically levitated in cryogenic free space pp. 378-382

Felix Tebbenjohanns, M. Luisa Mattana, Massimiliano Rossi, Martin Frimmer and Lukas Novotny

Amazonia as a carbon source linked to deforestation and climate change pp. 388-393

Luciana V. Gatti, Luana S. Basso, John B. Miller, Manuel Gloor, Lucas Gatti Domingues, Henrique L. G. Cassol, Graciela Tejada, Luiz E. O. C. Aragão, Carlos Nobre, Wouter Peters, Luciano Marani, Egidio Arai, Alber H. Sanches, Sergio M. Corrêa, Liana Anderson, Celso Randow, Caio S. C. Correia, Stephane P. Crispim and Raiane A. L. Neves

A lithium-isotope perspective on the evolution of carbon and silicon cycles pp. 394-398

Boriana Kalderon-Asael, Joachim A. R. Katchinoff, Noah J. Planavsky, Ashleigh v. S. Hood, Mathieu Dellinger, Eric J. Bellefroid, David S. Jones, Axel Hofmann, Frantz Ossa Ossa, Francis A. Macdonald, Chunjiang Wang, Terry T. Isson, Jack G. Murphy, John A. Higgins, A. Joshua West, Malcolm W. Wallace, Dan Asael and Philip A. E. Pogge von Strandmann

Pleistocene sediment DNA reveals hominin and faunal turnovers at Denisova Cave pp. 399-403

Elena I. Zavala, Zenobia Jacobs, Benjamin Vernot, Michael V. Shunkov, Maxim B. Kozlikin, Anatoly P. Derevianko, Elena Essel, Cesare Fillipo, Sarah Nagel, Julia Richter, Frédéric Romagné, Anna Schmidt, Bo Li, Kieran O’Gorman, Viviane Slon, Janet Kelso, Svante Pääbo, Richard G. Roberts and Matthias Meyer

Mechanism of disease and therapeutic rescue of Dok7 congenital myasthenia pp. 404-408

Julien Oury, Wei Zhang, Nadia Leloup, Akiko Koide, Alexis D. Corrado, Gayatri Ketavarapu, Takamitsu Hattori, Shohei Koide and Steven J. Burden

Microbiota regulate social behaviour via stress response neurons in the brain pp. 409-414

Wei-Li Wu, Mark D. Adame, Chia-Wei Liou, Jacob T. Barlow, Tzu-Ting Lai, Gil Sharon, Catherine E. Schretter, Brittany D. Needham, Madelyn I. Wang, Weiyi Tang, James Ousey, Yuan-Yuan Lin, Tzu-Hsuan Yao, Reem Abdel-Haq, Keith Beadle, Viviana Gradinaru, Rustem F. Ismagilov and Sarkis K. Mazmanian

A metabolomics pipeline for the mechanistic interrogation of the gut microbiome pp. 415-420

Shuo Han, Will Treuren, Curt R. Fischer, Bryan D. Merrill, Brian C. DeFelice, Juan M. Sanchez, Steven K. Higginbottom, Leah Guthrie, Lalla A. Fall, Dylan Dodd, Michael A. Fischbach and Justin L. Sonnenburg

SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans pp. 421-425

Jackson S. Turner, Wooseob Kim, Elizaveta Kalaidina, Charles W. Goss, Adriana M. Rauseo, Aaron J. Schmitz, Lena Hansen, Alem Haile, Michael K. Klebert, Iskra Pusic, Jane A. O’Halloran, Rachel M. Presti and Ali H. Ellebedy

Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection pp. 426-431

Zijun Wang, Frauke Muecksch, Dennis Schaefer-Babajew, Shlomo Finkin, Charlotte Viant, Christian Gaebler, Hans- Heinrich Hoffmann, Christopher O. Barnes, Melissa Cipolla, Victor Ramos, Thiago Y. Oliveira, Alice Cho, Fabian Schmidt, Justin Silva, Eva Bednarski, Lauren Aguado, Jim Yee, Mridushi Daga, Martina Turroja, Katrina G. Millard, Mila Jankovic, Anna Gazumyan, Zhen Zhao, Charles M. Rice, Paul D. Bieniasz, Marina Caskey, Theodora Hatziioannou and Michel C. Nussenzweig

ctDNA guiding adjuvant immunotherapy in urothelial carcinoma pp. 432-437

Thomas Powles, Zoe June Assaf, Nicole Davarpanah, Romain Banchereau, Bernadett E. Szabados, Kobe C. Yuen, Petros Grivas, Maha Hussain, Stephane Oudard, Jürgen E. Gschwend, Peter Albers, Daniel Castellano, Hiroyuki Nishiyama, Siamak Daneshmand, Shruti Sharma, Bernhard G. Zimmermann, Himanshu Sethi, Alexey Aleshin, Maurizio Perdicchio, Jingbin Zhang, David S. Shames, Viraj Degaonkar, Xiaodong Shen, Corey Carter, Carlos Bais, Joaquim Bellmunt and Sanjeev Mariathasan

A transcriptional switch governs fibroblast activation in heart disease pp. 438-443

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, Arun Padmanabhan, Lin Ye, Joshua G. Travers, Barbara Gonzalez-Teran, Ana Catarina Silva, Qiming Duan, Sanjeev S. Ranade, Franco Felix, Ricardo Linares-Saldana, Li Li, Clara Youngna Lee, Nandhini Sadagopan, Angelo Pelonero, Yu Huang, Gaia Andreoletti, Rajan Jain, Timothy A. McKinsey, Michael G. Rosenfeld, Casey A. Gifford, Katherine S. Pollard, Saptarsi M. Haldar and Deepak Srivastava

Shape of promoter antisense RNAs regulates ligand-induced transcription activation pp. 444-449

Fan Yang, Bogdan Tanasa, Rudi Micheletti, Kenneth A. Ohgi, Aneel K. Aggarwal and Michael G. Rosenfeld

G-protein activation by a metabotropic glutamate receptor pp. 450-454

Alpay B. Seven, Ximena Barros-Álvarez, Marine Lapeyrière, Makaía M. Papasergi-Scott, Michael J. Robertson, Chensong Zhang, Robert M. Nwokonko, Yang Gao, Justin G. Meyerowitz, Jean-Philippe Rocher, Dominik Schelshorn, Brian K. Kobilka, Jesper M. Mathiesen and Georgios Skiniotis

Asymmetric activation of the calcium-sensing receptor homodimer pp. 455-459

Yang Gao, Michael J. Robertson, Sabrina N. Rahman, Alpay B. Seven, Chensong Zhang, Justin G. Meyerowitz, Ouliana Panova, Fadil M. Hannan, Rajesh V. Thakker, Hans Bräuner-Osborne, Jesper M. Mathiesen and Georgios Skiniotis

Being fluent in a second language can boost your research pp. 461-461

Jamie Sugrue

Impact factor abandoned by Dutch university in hiring and promotion decisions pp. 462-462

Chris Woolston

Tracking Chernobyl’s effects on wildlife pp. 464-464

Virginia Gewin

2021, volume 595, articles 7866

Shark mortality cannot be assessed by fishery overlap alone pp. E4-E7

Hilario Murua, Shane P. Griffiths, Alistair J. Hobday, Shelley C. Clarke, Enric Cortés, Eric L. Gilman, Josu Santiago, Haritz Arrizabalaga, Paul Bruyn, Jon Lopez, Alexandre M. Aires-da-Silva and Victor Restrepo

Reply to: Shark mortality cannot be assessed by fishery overlap alone pp. E8-E16

Nuno Queiroz, Nicolas E. Humphries, Ana Couto, Marisa Vedor, Ivo Costa, Ana M. M. Sequeira, Gonzalo Mucientes, António M. Santos, Francisco J. Abascal, Debra L. Abercrombie, Katya Abrantes, David Acuña-Marrero, André S. Afonso, Pedro Afonso, Darrell Anders, Gonzalo Araujo, Randall Arauz, Pascal Bach, Adam Barnett, Diego Bernal, Michael L. Berumen, Sandra Bessudo Lion, Natalia P. A. Bezerra, Antonin V. Blaison, Barbara A. Block, Mark E. Bond, Ramon Bonfil, Russell W. Bradford, Camrin D. Braun, Edward J. Brooks, Annabelle Brooks, Judith Brown, Barry D. Bruce, Michael E. Byrne, Steven E. Campana, Aaron B. Carlisle, Demian D. Chapman, Taylor K. Chapple, John Chisholm, Christopher R. Clarke, Eric G. Clua, Jesse E. M. Cochran, Estelle C. Crochelet, Laurent Dagorn, Ryan Daly, Daniel Devia Cortés, Thomas K. Doyle, Michael Drew, Clinton A. J. Duffy, Thor Erikson, Eduardo Espinoza, Luciana C. Ferreira, Francesco Ferretti, John D. Filmalter, G. Chris Fischer, Richard Fitzpatrick, Jorge Fontes, Fabien Forget, Mark Fowler, Malcolm P. Francis, Austin J. Gallagher, Enrico Gennari, Simon D. Goldsworthy, Matthew J. Gollock, Jonathan R. Green, Johan A. Gustafson, Tristan L. Guttridge, Hector M. Guzman, Neil Hammerschlag, Luke Harman, Fábio H. V. Hazin, Matthew Heard, Alex R. Hearn, John C. Holdsworth, Bonnie J. Holmes, Lucy A. Howey, Mauricio Hoyos, Robert E. Hueter, Nigel E. Hussey, Charlie Huveneers, Dylan T. Irion, David M. P. Jacoby, Oliver J. D. Jewell, Ryan Johnson, Lance K. B. Jordan, Warren Joyce, Clare A. Keating Daly, James T. Ketchum, A. Peter Klimley, Alison A. Kock, Pieter Koen, Felipe Ladino, Fernanda O. Lana, James S. E. Lea, Fiona Llewellyn, Warrick S. Lyon, Anna MacDonnell, Bruno C. L. Macena, Heather Marshall, Jaime D. McAllister, Michael A. Meÿer, John J. Morris, Emily R. Nelson, Yannis P. Papastamatiou, Cesar Peñaherrera-Palma, Simon J. Pierce, Francois Poisson, Lina Maria Quintero, Andrew J. Richardson, Paul J. Rogers, Christoph A. Rohner, David R. L. Rowat, Melita Samoilys, Jayson M. Semmens, Marcus Sheaves, George Shillinger, Mahmood Shivji, Sarika Singh, Gregory B. Skomal, Malcolm J. Smale, Laurenne B. Snyders, German Soler, Marc Soria, Kilian M. Stehfest, Simon R. Thorrold, Mariana T. Tolotti, Alison Towner, Paulo Travassos, John P. Tyminski, Frederic Vandeperre, Jeremy J. Vaudo, Yuuki Y. Watanabe, Sam B. Weber, Bradley M. Wetherbee, Timothy D. White, Sean Williams, Patricia M. Zárate, Robert Harcourt, Graeme C. Hays, Mark G. Meekan, Michele Thums, Xabier Irigoien, Victor M. Eguiluz, Carlos M. Duarte, Lara L. Sousa, Samantha J. Simpson, Emily J. Southall and David W. Sims

Caution over the use of ecological big data for conservation pp. E17-E19

Alastair V. Harry and J. Matias Braccini

Reply to: Caution over the use of ecological big data for conservation pp. E20-E28

Nuno Queiroz, Nicolas E. Humphries, Ana Couto, Marisa Vedor, Ivo Costa, Ana M. M. Sequeira, Gonzalo Mucientes, António M. Santos, Francisco J. Abascal, Debra L. Abercrombie, Katya Abrantes, David Acuña-Marrero, André S. Afonso, Pedro Afonso, Darrell Anders, Gonzalo Araujo, Randall Arauz, Pascal Bach, Adam Barnett, Diego Bernal, Michael L. Berumen, Sandra Bessudo Lion, Natalia P. A. Bezerra, Antonin V. Blaison, Barbara A. Block, Mark E. Bond, Ramon Bonfil, Camrin D. Braun, Edward J. Brooks, Annabelle Brooks, Judith Brown, Michael E. Byrne, Steven E. Campana, Aaron B. Carlisle, Demian D. Chapman, Taylor K. Chapple, John Chisholm, Christopher R. Clarke, Eric G. Clua, Jesse E. M. Cochran, Estelle C. Crochelet, Laurent Dagorn, Ryan Daly, Daniel Devia Cortés, Thomas K. Doyle, Michael Drew, Clinton A. J. Duffy, Thor Erikson, Eduardo Espinoza, Luciana C. Ferreira, Francesco Ferretti, John D. Filmalter, G. Chris Fischer, Richard Fitzpatrick, Jorge Fontes, Fabien Forget, Mark Fowler, Malcolm P. Francis, Austin J. Gallagher, Enrico Gennari, Simon D. Goldsworthy, Matthew J. Gollock, Jonathan R. Green, Johan A. Gustafson, Tristan L. Guttridge, Hector M. Guzman, Neil Hammerschlag, Luke Harman, Fábio H. V. Hazin, Matthew Heard, Alex R. Hearn, John C. Holdsworth, Bonnie J. Holmes, Lucy A. Howey, Mauricio Hoyos, Robert E. Hueter, Nigel E. Hussey, Charlie Huveneers, Dylan T. Irion, David M. P. Jacoby, Oliver J. D. Jewell, Ryan Johnson, Lance K. B. Jordan, Warren Joyce, Clare A. Keating Daly, James T. Ketchum, A. Peter Klimley, Alison A. Kock, Pieter Koen, Felipe Ladino, Fernanda O. Lana, James S. E. Lea, Fiona Llewellyn, Warrick S. Lyon, Anna MacDonnell, Bruno C. L. Macena, Heather Marshall, Jaime D. McAllister, Michael A. Meÿer, John J. Morris, Emily R. Nelson, Yannis P. Papastamatiou, Cesar Peñaherrera-Palma, Simon J. Pierce, Francois Poisson, Lina Maria Quintero, Andrew J. Richardson, Paul J. Rogers, Christoph A. Rohner, David R. L. Rowat, Melita Samoilys, Jayson M. Semmens, Marcus Sheaves, George Shillinger, Mahmood Shivji, Sarika Singh, Gregory B. Skomal, Malcolm J. Smale, Laurenne B. Snyders, German Soler, Marc Soria, Kilian M. Stehfest, Simon R. Thorrold, Mariana T. Tolotti, Alison Towner, Paulo Travassos, John P. Tyminski, Frederic Vandeperre, Jeremy J. Vaudo, Yuuki Y. Watanabe, Sam B. Weber, Bradley M. Wetherbee, Timothy D. White, Sean Williams, Patricia M. Zárate, Robert Harcourt, Graeme C. Hays, Mark G. Meekan, Michele Thums, Xabier Irigoien, Victor M. Eguiluz, Carlos M. Duarte, Lara L. Sousa, Samantha J. Simpson, Emily J. Southall and David W. Sims

Treatment of missing data determined conclusions regarding moralizing gods pp. E29-E34

Bret Beheim, Quentin D. Atkinson, Joseph Bulbulia, Will Gervais, Russell D. Gray, Joseph Henrich, Martin Lang, M. Willis Monroe, Michael Muthukrishna, Ara Norenzayan, Benjamin Grant Purzycki, Azim Shariff, Edward Slingerland, Rachel Spicer and Aiyana K. Willard

Author Correction: Assembly of synaptic active zones requires phase separation of scaffold molecules pp. E35-E35

Nathan A. McDonald, Richard D. Fetter and Kang Shen

Beware performative reproducibility pp. 151-151

Stuart Buck

Black scientist network celebrates successes — but calls for more support pp. 157-158

Ariana Remmel

Killing at Chinese university highlights tensions over tenure system pp. 158-159

Smriti Mallapaty

Deadly Myanmar mine disaster caused by poor planning, say data sleuths pp. 160-161

Andrew Silver

Is one vaccine dose enough if you’ve had COVID? What the science says pp. 161-162

Elie Dolgin

Controversial Alzheimer’s drug approval could affect other diseases pp. 162-163

Asher Mullard

COVID and schools: the evidence for reopening safely pp. 164-167

Cassandra Willyard

Ei-ichi Negishi (1935–2021) pp. 168-168

Kit Chapman

Everyone should decide how their digital data are used — not just tech companies pp. 169-171

Jathan Sadowski, Salomé Viljoen and Meredith Whittaker

Protect pollinators — reform pesticide regulations pp. 172-172

Adrian Fisher

UK biodiversity: close gap between reality and rhetoric pp. 172-172

Sophus O. S. E. zu Ermgassen, Joseph W. Bull and Ben Groom

China’s homeless elephants need linked reserves pp. 172-172

Nian Yang, Wenwen Li, Peng Liu and Li Zhang

COVID-19: living guidelines help fix cracks in evidence pipeline pp. 172-172

Per Olav Vandvik, Lisa Askie, Fiona Glen, Britta Tendal and Thomas Agoritsas

Malaria vaccine gets a parasite boost in the liver pp. 173-174

Nana K. Minkah and Stefan H. I. Kappe

How to buffer against an urban food shortage pp. 175-176

Zia Mehrabi

Engineered single-domain antibodies tackle COVID variants pp. 176-178

James E. Voss

Fluid-rich extinct volcanoes cause small earthquakes beneath New Zealand pp. 178-179

Catherine A. Rychert and Nicholas Harmon

Integrating explanation and prediction in computational social science pp. 181-188

Jake M. Hofman, Duncan J. Watts, Susan Athey, Filiz Garip, Thomas L. Griffiths, Jon Kleinberg, Helen Margetts, Sendhil Mullainathan, Matthew J. Salganik, Simine Vazire, Alessandro Vespignani and Tal Yarkoni

Meaningful measures of human society in the twenty-first century pp. 189-196

David Lazer, Eszter Hargittai, Deen Freelon, Sandra Gonzalez-Bailon, Kevin Munger, Katherine Ognyanova and Jason Radford

Measuring algorithmically infused societies pp. 197-204

Claudia Wagner, Markus Strohmaier, Alexandra Olteanu, Emre Kıcıman, Noshir Contractor and Tina Eliassi-Rad

Thinking clearly about social aspects of infectious disease transmission pp. 205-213

Caroline Buckee, Abdisalan Noor and Lisa Sattenspiel

Human social sensing is an untapped resource for computational social science pp. 214-222

Mirta Galesic, Wändi Bruine de Bruin, Jonas Dalege, Scott L. Feld, Frauke Kreuter, Henrik Olsson, Drazen Prelec, Daniel L. Stein and Tamara van der Does

r-Process elements from magnetorotational hypernovae pp. 223-226

D. Yong, C. Kobayashi, G. S. Costa, M. S. Bessell, A. Chiti, A. Frebel, K. Lind, A. D. Mackey, T. Nordlander, M. Asplund, A. R. Casey, A. F. Marino, S. J. Murphy and B. P. Schmidt

Quantum phases of matter on a 256-atom programmable quantum simulator pp. 227-232

Sepehr Ebadi, Tout T. Wang, Harry Levine, Alexander Keesling, Giulia Semeghini, Ahmed Omran, Dolev Bluvstein, Rhine Samajdar, Hannes Pichler, Wen Wei Ho, Soonwon Choi, Subir Sachdev, Markus Greiner, Vladan Vuletić and Mikhail D. Lukin

Quantum simulation of 2D antiferromagnets with hundreds of Rydberg atoms pp. 233-238

Pascal Scholl, Michael Schuler, Hannah J. Williams, Alexander A. Eberharter, Daniel Barredo, Kai-Niklas Schymik, Vincent Lienhard, Louis-Paul Henry, Thomas C. Lang, Thierry Lahaye, Andreas M. Läuchli and Antoine Browaeys

Optical manipulation of electronic dimensionality in a quantum material pp. 239-244

Shaofeng Duan, Yun Cheng, Wei Xia, Yuanyuan Yang, Chengyang Xu, Fengfeng Qi, Chaozhi Huang, Tianwei Tang, Yanfeng Guo, Weidong Luo, Dong Qian, Dao Xiang, Jie Zhang and Wentao Zhang

Bifunctional nanoprecipitates strengthen and ductilize a medium-entropy alloy pp. 245-249

Ying Yang, Tianyi Chen, Lizhen Tan, Jonathan D. Poplawsky, Ke An, Yanli Wang, German D. Samolyuk, Ken Littrell, Andrew R. Lupini, Albina Borisevich and Easo P. George

Supply chain diversity buffers cities against food shocks pp. 250-254

Michael Gomez, Alfonso Mejia, Benjamin L. Ruddell and Richard R. Rushforth

Fluid-rich subducting topography generates anomalous forearc porosity pp. 255-260

Christine Chesley, Samer Naif, Kerry Key and Dan Bassett

GluD1 is a signal transduction device disguised as an ionotropic receptor pp. 261-265

Jinye Dai, Christopher Patzke, Kif Liakath-Ali, Erica Seigneur and Thomas C. Südhof

Obesity accelerates hair thinning by stem cell-centric converging mechanisms pp. 266-271

Hironobu Morinaga, Yasuaki Mohri, Marina Grachtchouk, Kyosuke Asakawa, Hiroyuki Matsumura, Motohiko Oshima, Naoya Takayama, Tomoki Kato, Yuriko Nishimori, Yuriko Sorimachi, Keiyo Takubo, Takayoshi Suganami, Atsushi Iwama, Yoichiro Iwakura, Andrzej A. Dlugosz and Emi K. Nishimura

Caloric restriction disrupts the microbiota and colonization resistance pp. 272-277

Reiner Jumpertz Schwartzenberg, Jordan E. Bisanz, Svetlana Lyalina, Peter Spanogiannopoulos, Qi Yan Ang, Jingwei Cai, Sophia Dickmann, Marie Friedrich, Su-Yang Liu, Stephanie L. Collins, Danielle Ingebrigtsen, Steve Miller, Jessie A. Turnbaugh, Andrew D. Patterson, Katherine S. Pollard, Knut Mai, Joachim Spranger and Peter J. Turnbaugh

Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants pp. 278-282

Jianliang Xu, Kai Xu, Seolkyoung Jung, Andrea Conte, Jenna Lieberman, Frauke Muecksch, Julio Cesar Cetrulo Lorenzi, Solji Park, Fabian Schmidt, Zijun Wang, Yaoxing Huang, Yang Luo, Manoj S. Nair, Pengfei Wang, Jonathan E. Schulz, Lino Tessarollo, Tatsiana Bylund, Gwo-Yu Chuang, Adam S. Olia, Tyler Stephens, I-Ting Teng, Yaroslav Tsybovsky, Tongqing Zhou, Vincent Munster, David D. Ho, Theodora Hatziioannou, Paul D. Bieniasz, Michel C. Nussenzweig, Peter D. Kwong and Rafael Casellas

Diverse functional autoantibodies in patients with COVID-19 pp. 283-288

Eric Y. Wang, Tianyang Mao, Jon Klein, Yile Dai, John D. Huck, Jillian R. Jaycox, Feimei Liu, Ting Zhou, Benjamin Israelow, Patrick Wong, Andreas Coppi, Carolina Lucas, Julio Silva, Ji Eun Oh, Eric Song, Emily S. Perotti, Neil S. Zheng, Suzanne Fischer, Melissa Campbell, John B. Fournier, Anne L. Wyllie, Chantal B. F. Vogels, Isabel M. Ott, Chaney C. Kalinich, Mary E. Petrone, Anne E. Watkins, Charles Cruz, Shelli F. Farhadian, Wade L. Schulz, Shuangge Ma, Nathan D. Grubaugh, Albert I. Ko, Akiko Iwasaki and Aaron M. Ring

Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity pp. 289-294

Agnes Mwakingwe-Omari, Sara A. Healy, Jacquelyn Lane, David M. Cook, Sahand Kalhori, Charles Wyatt, Aarti Kolluri, Omely Marte-Salcedo, Alemush Imeru, Martha Nason, Lei K. Ding, Hope Decederfelt, Junhui Duan, Jillian Neal, Jacob Raiten, Grace Lee, Jen C. C. Hume, Jihyun E. Jeon, Ijeoma Ikpeama, Natasha Kc, Sumana Chakravarty, Tooba Murshedkar, L. W. Preston Church, Anita Manoj, Anusha Gunasekera, Charles Anderson, Sean C. Murphy, Sandra March, Sangeeta N. Bhatia, Eric R. James, Peter F. Billingsley, B. Kim Lee Sim, Thomas L. Richie, Irfan Zaidi, Stephen L. Hoffman and Patrick E. Duffy

Base editing of haematopoietic stem cells rescues sickle cell disease in mice pp. 295-302

Gregory A. Newby, Jonathan S. Yen, Kaitly J. Woodard, Thiyagaraj Mayuranathan, Cicera R. Lazzarotto, Yichao Li, Heather Sheppard-Tillman, Shaina N. Porter, Yu Yao, Kalin Mayberry, Kelcee A. Everette, Yoonjeong Jang, Christopher J. Podracky, Elizabeth Thaman, Christophe Lechauve, Akshay Sharma, Jordana M. Henderson, Michelle F. Richter, Kevin T. Zhao, Shannon M. Miller, Tina Wang, Luke W. Koblan, Anton P. McCaffrey, John F. Tisdale, Theodosia A. Kalfa, Shondra M. Pruett-Miller, Shengdar Q. Tsai, Mitchell J. Weiss and David R. Liu

NORAD-induced Pumilio phase separation is required for genome stability pp. 303-308

Mahmoud M. Elguindy and Joshua T. Mendell

Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity pp. 309-314

Gabriel K. Griffin, Jingyi Wu, Arvin Iracheta-Vellve, James C. Patti, Jeffrey Hsu, Thomas Davis, Deborah Dele-Oni, Peter P. Du, Aya G. Halawi, Jeffrey J. Ishizuka, Sarah Y. Kim, Susan Klaeger, Nelson H. Knudsen, Brian C. Miller, Tung H. Nguyen, Kira E. Olander, Malvina Papanastasiou, Suzanna Rachimi, Emily J. Robitschek, Emily M. Schneider, Mitchell D. Yeary, Margaret D. Zimmer, Jacob D. Jaffe, Steven A. Carr, John G. Doench, W. Nicholas Haining, Kathleen B. Yates, Robert T. Manguso and Bradley E. Bernstein

Structural basis of omega-3 fatty acid transport across the blood–brain barrier pp. 315-319

Rosemary J. Cater, Geok Lin Chua, Satchal K. Erramilli, James E. Keener, Brendon C. Choy, Piotr Tokarz, Cheen Fei Chin, Debra Q. Y. Quek, Brian Kloss, Joseph G. Pepe, Giacomo Parisi, Bernice H. Wong, Oliver B. Clarke, Michael T. Marty, Anthony A. Kossiakoff, George Khelashvili, David L. Silver and Filippo Mancia

Retraction Note: Complex societies precede moralizing gods throughout world history pp. 320-320

Harvey Whitehouse, Pieter François, Patrick E. Savage, Thomas E. Currie, Kevin C. Feeney, Enrico Cioni, Rosalind Purcell, Robert M. Ross, Jennifer Larson, John Baines, Barend Haar, Alan Covey and Peter Turchin

‘We’re problem solvers’: research administrators offer guidance to working scientists pp. 321-322

Sara Reardon

Shifting shores: delving into the past with mud cores pp. 324-324

Amber Dance

2021, volume 595, articles 7865

Materials science shows strength pp. S1-S1

Catherine Armitage

Author Correction: Spike mutation D614G alters SARS-CoV-2 fitness pp. E1-E1

Jessica A. Plante, Yang Liu, Jianying Liu, Hongjie Xia, Bryan A. Johnson, Kumari G. Lokugamage, Xianwen Zhang, Antonio E. Muruato, Jing Zou, Camila R. Fontes-Garfias, Divya Mirchandani, Dionna Scharton, John P. Bilello, Zhiqiang Ku, Zhiqiang An, Birte Kalveram, Alexander N. Freiberg, Vineet D. Menachery, Xuping Xie, Kenneth S. Plante, Scott C. Weaver and Pei-Yong Shi

Author Correction: REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity pp. E2-E2

Guolian Ding, Xin Li, Xinguo Hou, Wenjun Zhou, Yingyun Gong, Fuqiang Liu, Yanlin He, Jia Song, Jing Wang, Paul Basil, Wenbo Li, Sichong Qian, Pradip Saha, Jinbang Wang, Chen Cui, Tingting Yang, Kexin Zou, Younghun Han, Christopher I. Amos, Yong Xu, Li Chen and Zheng Sun

Author Correction: A pooled testing strategy for identifying SARS-CoV-2 at low prevalence pp. E3-E3

Leon Mutesa, Pacifique Ndishimye, Yvan Butera, Jacob Souopgui, Annette Uwineza, Robert Rutayisire, Ella Larissa Ndoricimpaye, Emile Musoni, Nadine Rujeni, Thierry Nyatanyi, Edouard Ntagwabira, Muhammed Semakula, Clarisse Musanabaganwa, Daniel Nyamwasa, Maurice Ndashimye, Eva Ujeneza, Ivan Emile Mwikarago, Claude Mambo Muvunyi, Jean Baptiste Mazarati, Sabin Nsanzimana, Neil Turok and Wilfred Ndifon

High-entropy alloys expand their range pp. S4-S5

Neil Savage

COVID’s lesson for climate research: go local pp. 9-9

Alice C. Hill

Astronomers victimized colleagues — and put historic Swedish department in turmoil pp. 15-16

Alexandra Witze

Birds of paradise reveal a dark secret pp. S17-S17

Katharine Sanderson

Delta coronavirus variant: scientists brace for impact pp. 17-18

Ewen Callaway

How nanotechnology can flick the immunity switch pp. S18-S19

Bianca Nogrady

Mathematicians welcome computer-assisted proof in ‘grand unification’ theory pp. 18-19

Davide Castelvecchi

Mysterious skull fossils expand human family tree — but questions remain pp. 20-20

Nicola Jones

Why Uruguay lost control of COVID pp. 21-21

Luke Taylor

Beyond coronavirus: the virus discoveries transforming biology pp. 22-25

Amber Dance

Makers and shakers pp. S23-S25

Catherine Armitage, Sandy Ong and Sian Powell

Yuan Longping (1930–2021) pp. 26-26

Shellen X. Wu

Five ways to ensure flood-risk research helps the most vulnerable pp. 27-29

Miyuki Hino and Earthea Nance

It is dangerous to normalize solar geoengineering research pp. 30-30

Frank Biermann

Boost vaccine confidence with trust, not ire pp. 30-30

Hari McGrath

Cameroon: doubt could mean vaccine doses expire pp. 30-30

Amani Adidja, Yap Boum and Pierre Ongolo-Zogo

Notice who the science system honours, and how pp. 30-30

Jason R. Dwyer

Programmable capillary action controls fluid flows pp. 31-32

Tammi L. van Neel and Ashleigh B. Theberge

Designer fibre meals sway human gut microbes pp. 32-34

Avner Leshem and Eran Elinav

Ferroelectric materials prompt a rethink of matter pp. S34-S35

Chris Woolston

Migratory birds aid the redistribution of plants to new climates pp. 34-36

Barnabas H. Daru

Machines learn to unearth new materials pp. S36-S36

Neil Savage

A base-pair view of interactions between genes and their enhancers pp. 36-37

Anne van Schoonhoven and Ralph Stadhouders

A highly magnetized and rapidly rotating white dwarf as small as the Moon pp. 39-42

Ilaria Caiazzo, Kevin B. Burdge, James Fuller, Jeremy Heyl, S. R. Kulkarni, Thomas A. Prince, Harvey B. Richer, Josiah Schwab, Igor Andreoni, Eric C. Bellm, Andrew Drake, Dmitry A. Duev, Matthew J. Graham, George Helou, Ashish A. Mahabal, Frank J. Masci, Roger Smith and Maayane T. Soumagnac

Demonstration of a trapped-ion atomic clock in space pp. 43-47

E. A. Burt, J. D. Prestage, R. L. Tjoelker, D. G. Enzer, D. Kuang, D. W. Murphy, D. E. Robison, J. M. Seubert, R. T. Wang and T. A. Ely

Bilayer Wigner crystals in a transition metal dichalcogenide heterostructure pp. 48-52

You Zhou, Jiho Sung, Elise Brutschea, Ilya Esterlis, Yao Wang, Giovanni Scuri, Ryan J. Gelly, Hoseok Heo, Takashi Taniguchi, Kenji Watanabe, Gergely Zaránd, Mikhail D. Lukin, Philip Kim, Eugene Demler and Hongkun Park

Signatures of Wigner crystal of electrons in a monolayer semiconductor pp. 53-57

Tomasz Smoleński, Pavel E. Dolgirev, Clemens Kuhlenkamp, Alexander Popert, Yuya Shimazaki, Patrick Back, Xiaobo Lu, Martin Kroner, Kenji Watanabe, Takashi Taniguchi, Ilya Esterlis, Eugene Demler and Ataç Imamoğlu

Cellular fluidics pp. 58-65

Nikola A. Dudukovic, Erika J. Fong, Hawi B. Gemeda, Joshua R. DeOtte, Maira R. Cerón, Bryan D. Moran, Jonathan T. Davis, Sarah E. Baker and Eric B. Duoss

Precise date for the Laacher See eruption synchronizes the Younger Dryas pp. 66-69

Frederick Reinig, Lukas Wacker, Olaf Jöris, Clive Oppenheimer, Giulia Guidobaldi, Daniel Nievergelt, Florian Adolphi, Paolo Cherubini, Stefan Engels, Jan Esper, Alexander Land, Christine Lane, Hardy Pfanz, Sabine Remmele, Michael Sigl, Adam Sookdeo and Ulf Büntgen

Ridgecrest aftershocks at Coso suppressed by thermal destressing pp. 70-74

Kyungjae Im, Jean-Philippe Avouac, Elías R. Heimisson and Derek Elsworth

Limited potential for bird migration to disperse plants to cooler latitudes pp. 75-79

Juan P. González-Varo, Beatriz Rumeu, Jörg Albrecht, Juan M. Arroyo, Rafael S. Bueno, Tamara Burgos, Luís P. da Silva, Gema Escribano-Ávila, Nina Farwig, Daniel García, Ruben H. Heleno, Juan C. Illera, Pedro Jordano, Przemysław Kurek, Benno I. Simmons, Emilio Virgós, William J. Sutherland and Anna Traveset

Geometry of abstract learned knowledge in the hippocampus pp. 80-84

Edward H. Nieh, Manuel Schottdorf, Nicolas W. Freeman, Ryan J. Low, Sam Lewallen, Sue Ann Koay, Lucas Pinto, Jeffrey L. Gauthier, Carlos D. Brody and David W. Tank

Lineage tracing of human development through somatic mutations pp. 85-90

Michael Spencer Chapman, Anna Maria Ranzoni, Brynelle Myers, Nicholas Williams, Tim H. H. Coorens, Emily Mitchell, Timothy Butler, Kevin J. Dawson, Yvette Hooks, Luiza Moore, Jyoti Nangalia, Philip S. Robinson, Kenichi Yoshida, Elizabeth Hook, Peter J. Campbell and Ana Cvejic

Evaluating microbiome-directed fibre snacks in gnotobiotic mice and humans pp. 91-95

Omar Delannoy-Bruno, Chandani Desai, Arjun S. Raman, Robert Y. Chen, Matthew C. Hibberd, Jiye Cheng, Nathan Han, Juan J. Castillo, Garret Couture, Carlito B. Lebrilla, Ruteja A. Barve, Vincent Lombard, Bernard Henrissat, Semen A. Leyn, Dmitry A. Rodionov, Andrei L. Osterman, David K. Hayashi, Alexandra Meynier, Sophie Vinoy, Kyleigh Kirbach, Tara Wilmot, Andrew C. Heath, Samuel Klein, Michael J. Barratt and Jeffrey I. Gordon

An invariant Trypanosoma vivax vaccine antigen induces protective immunity pp. 96-100

Delphine Autheman, Cécile Crosnier, Simon Clare, David A. Goulding, Cordelia Brandt, Katherine Harcourt, Charlotte Tolley, Francis Galaway, Malhar Khushu, Han Ong, Alessandra Romero-Ramirez, Craig W. Duffy, Andrew P. Jackson and Gavin J. Wright

TIM-3 restrains anti-tumour immunity by regulating inflammasome activation pp. 101-106

Karen O. Dixon, Marcin Tabaka, Markus A. Schramm, Sheng Xiao, Ruihan Tang, Danielle Dionne, Ana. C. Anderson, Orit Rozenblatt-Rosen, Aviv Regev and Vijay K. Kuchroo

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets pp. 107-113

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