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2000, volume 403, articles 6772

Eros begins to yield up its secrets pp. 815-815

Tony Reichhardt

Celera in talks to launch private sector human proteome project pp. 815-816

Declan Butler

Biomedical centre memorial to victims of Nazi research pp. 816-816

Patrick Weydt

Australian industry ‘starving’ R&D pp. 816-816

Peter Pockley

Merck blocks ‘safer’ gene therapy trials pp. 817-817

Paul Smaglik

Celera's shotgun approach puts Drosophila in the bag pp. 817-817

Natasha Loder

Med school to relax rules on business links? pp. 818-818

Steve Nadis

Spanish boost for young scientists pp. 818-818

Xavier Bosch

Japan set to tighten ethics rules for genetic sampling pp. 819-820

Robert Triendl

AAAS members fret over links with theological foundation pp. 819-819

Colin Macilwain

Gene therapy institute denies that errors led to trial death pp. 820-820

Paul Smaglik

US physics society puts feisty newsletter in doubt pp. 820-820

Colin Macilwain

Germany holds up cultivation of GM maize… pp. 821-821

Alison Abbott

… amid calls for international biotech panel pp. 821-821

David Dickson

Open annotation offers a democratic solution to genome sequencing pp. 825-825

Tim Hubbard and Ewan Birney

Affirmative action won't solve sex discrimination pp. 825-825

G.A. Lozano

Why Roche deserves the disputed Taq patent pp. 825-826

T. J. White

ECT has proved effective in treating depression… pp. 826-826

Max Fink

… and there's no proof of lasting brain damage pp. 826-826

Richard Abrams

Shrinking shrews pp. 826-826

D.W. Yalden

Cloning shock: was Dolly a three-legged accident? pp. 826-826

Wendy Gibson

A picaresque genius pp. 827-828

Gunther S. Stent

Enter the cosmic cathedral pp. 828-829

P. M. Solomon

India's fruitful tryst with technology pp. 829-830

V.S. Arunachalam

Science in culture pp. 830-830

Douglas Palmer

Fighting the wrong battle pp. 831-831

Geoffrey Cantor

Avatars in space pp. 833-833

Geoffrey A. Landis

Proteomics for the pore pp. 835-836

Günter Blobel and Richard W. Wozniak

As weird as they come pp. 836-837

Volker Heine

Tepid tastes pp. 837-839

Robert A. Frank

A shear pathway to the core pp. 839-840

Michael J. Walter

A social stigma pp. 840-841

Teh-hui Kao and Andrew G. McCubbin

Galaxy formation in action pp. 841-843

Gary Welch

Extinction by numbers pp. 843-845

Stuart L. Pimm and Peter Raven

Attosecond pulses at last pp. 845-846

Paul Corkum

The bulge of Casita pp. 846-846

Tim Lincoln

Neurofibromin progress on the fly pp. 846-847

Ronald L. Davis

Grinding waste away pp. 847-847

David Jones

Paul Sigler (1934–2000) pp. 848-848

Brian W. Matthews

The sound of many hands clapping pp. 849-850

Z. Néda, E. Ravasz, Y. Brechet, T. Vicsek and A.-L. Barabási

reply: Leptin and diabetes in lipoatrophic mice pp. 850-851

Iichiro Shimomura, Robert E. Hammer, Shinji Ikemoto, Michael S. Brown and Joseph L. Goldstein

Leptin and diabetes in lipoatrophic mice pp. 850-850

Oksana Gavrilova, Bernice Marcus-Samuels, Lisa R. Leon, Charles Vinson and Marc L. Reitman

Exploitation of gut bacteria in the locust pp. 851-851

Rod J. Dillon, Chris T. Vennard and A. Keith Charnley

Recovery of breeding success in wild birds pp. 851-852

Tapio Eeva and Esa Lehikoinen

Biodiversity hotspots for conservation priorities pp. 853-858

Norman Myers, Russell A. Mittermeier, Cristina G. Mittermeier, Gustavo A. B. da Fonseca and Jennifer Kent

Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA pp. 859-866

Steven D. Bruner, Derek P. G. Norman and Gregory L. Verdine

Formation of molecular gas in the tidal debris of violent galaxy–galaxy interactions pp. 867-869

Jonathan Braine, Ute Lisenfeld, Pierre-Alain Due and Stéphane Leon

Geometric quantum computation using nuclear magnetic resonance pp. 869-871

Jonathan A. Jones, Vlatko Vedral, Artur Ekert and Giuseppe Castagnoli

Reduction in the surface energy of liquid interfaces at short length scales pp. 871-874

C. Fradin, A. Braslau, D. Luzet, D. Smilgies, M. Alba, N. Boudet, K. Mecke and J. Daillant

Electrically induced structure formation and pattern transfer pp. 874-877

Erik Schäffer, Thomas Thurn-Albrecht, Thomas P. Russell and Ullrich Steiner

Variations of Younger Dryas atmospheric radiocarbon explicable without ocean circulation changes pp. 877-880

Tomasz Goslar, Maurice Arnold, Nadine Tisnerat-Laborde, Justyna Czernik and Kazimierz Wiȩckowski

A thermodynamic explanation for black smoker temperatures pp. 880-883

Tim Jupp and Adam Schultz

An interconnected network of core-forming melts produced by shear deformation pp. 883-886

D. Bruhn, N. Groebner and D. L. Kohlstedt

Rapid evolution of reproductive barriers driven by sexual conflict pp. 886-889

Sergey Gavrilets

Thermal stimulation of taste pp. 889-892

Alberto Cruz and Barry G. Green

Postsaccadic visual references generate presaccadic compression of space pp. 892-895

Markus Lappe, Holger Awater and Bart Krekelberg

A neurofibromatosis-1-regulated pathway is required for learning in Drosophila pp. 895-898

Hui-Fu Guo, Jiayuan Tong, Frances Hannan, Lin Luo and Yi Zhong

Three distinct and sequential steps in the release of sodium ions by the Na+/K+-ATPase pp. 898-901

Miguel Holmgren, Jonathan Wagg, Francisco Bezanilla, Robert F. Rakowski, Paul De Weer and David C. Gadsby

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans pp. 901-906

Brenda J. Reinhart, Frank J. Slack, Michael Basson, Amy E. Pasquinelli, Jill C. Bettinger, Ann E. Rougvie, H. Robert Horvitz and Gary Ruvkun

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum pp. 906-909

Michael B. Reed, Kevin J. Saliba, Sonia R. Caruana, Kiaran Kirk and Alan F. Cowman

The LIM homeobox gene Lhx9 is essential for mouse gonad formation pp. 909-913

Ohad S. Birk, Delane E. Casiano, Christopher A. Wassif, Tiziana Cogliati, Liping Zhao, Yangu Zhao, Alexander Grinberg, SingPing Huang, Jordan A. Kreidberg, Keith L. Parker, Forbes D. Porter and Heiner Westphal

The S receptor kinase determines self-incompatibility in Brassica stigma pp. 913-916

Takeshi Takasaki, Katsunori Hatakeyama, Go Suzuki, Masao Watanabe, Akira Isogai and Kokichi Hinata

Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding pp. 916-921

Ketan S. Gajiwala, Hua Chen, Fabrice Cornille, Bernard P. Roques, Walter Reith, Bernard Mach and Stephen K. Burley

Structure of a ligand-binding intermediate in wild-type carbonmonoxy myoglobin pp. 921-923

Kelvin Chu, Jaroslav Vojtchovský, Benjamin H. McMahon, Robert M. Sweet, Joel Berendzen and Ilme Schlichting

2000, volume 403, articles 6771

UK scientists under pressure to please pp. 689-689

Natasha Loder

Feathers fly over Chinese fossil bird's legality and authenticity pp. 689-690

Rex Dalton

The biggest, wildest fossil market in the west pp. 690-690

Rex Dalton

Protein structure groups seek to draft common ground rules pp. 691-691

Paul Smaglik

Austrian body pleads for normal contacts despite EU freeze pp. 691-691

Quirin Schiermeier and Patrick Weydt

South African government rejects AZT advice pp. 692-692

Michael Cherry

Consortium aims to kick-start TB research pp. 692-692

Declan Butler

Europe's X-ray observatory defies the jinx… pp. 693-693

Alison Abbott

…but Astro-E is yet another Japanese failure pp. 693-693

Robert Triendl

Russian presidential favourite pledges support for science pp. 694-694

Carl Levitin

Republican candidates clash on fetal tissue in research pp. 694-694

Meredith Wadman

Funding crisis for Indian biotech centre pp. 694-694

K. S. Jayaraman

Oxford professor faces business link inquiry pp. 695-695

Natasha Loder

Reliance on the citation index undermines the study of biodiversity pp. 698-698

Antonio G. Valdecasas, Santiago Castroviejo and Leslie F. Marcus

Proteomics could be key in battle against malaria pp. 698-698

Virendra K. Bhasin

X chromosomes forget where they came from pp. 698-698

Anne McLaren

Don't let politics put Diamond at risk pp. 698-698

James H. Naismith

One-stop shop for microarray data pp. 699-700

Alvis Brazma, Alan Robinson, Graham Cameron and Michael Ashburner

Balancing ambition and restraint pp. 701-702

Robert W. Cahn

Between heavens and cloister pp. 702-703

Brenda Maddox

Problem squares and virtuous circles pp. 703-704

Jeremy Gray

A rival for the Burgess Shale pp. 703-703

Douglas Palmer

Science in culture pp. 704-704

Martin Kemp

Where do babies come from? pp. 705-705

R.V. Short

Total internal reflection pp. 707-707

Gwyneth Jones

Taiwan's gift to the world pp. 709-710

Jared M. Diamond

Sidestepping the selection rules pp. 710-711

I. D. W. Samuel and A. Beeby

Mining the genome for iron pp. 711-713

Jerry Kaplan and James P. Kushner

The hole record pp. 714-715

Jonathan T. Overpeck

A provirus put to work pp. 715-717

Jonathan P. Stoye and John M Coffin

From obscurity to impurity pp. 717-718

A. V. Balatsky

The complexity of co-dependency pp. 718-719

Peter J. Morin

A gathering of groups pp. 719-720

Ian Stewart

Raising the roof pp. 720-721

Miguel Manzanares and Robb Krumlauf

Down-gazing Dome pp. 721-721

David Jones

Dennis Sciama (1926–99) pp. 722-722

George F.R Ellis

Conversion of diploidy to haploidy pp. 723-724

Hai Yan, Nickolas Papadopoulos, Giancarlo Marra, Claudia Perrera, Josef Jiricny, C. Richard Boland, Henry T. Lynch, Robert B. Chadwick, Albert de la Chapelle, Karin Berg, James R. Eshleman, Weishi Yuan, Sanford Markowitz, Steven J. Laken, Christoph Lengauer, Kenneth W. Kinzler and Bert Vogelstein

Reactivation of Borrelia infection in birds pp. 724-725

Åsa Gylfe, Sven Bergström, Jan Lundstróm and Björn Olsen

Do mussels take wooden steps to deep-sea vents? pp. 725-726

Daniel L. Distel, Amy R. Baco, Ellie Chuang, Wendy Morrill, Colleen Cavanaugh and Craig R. Smith

Supernova explosions in the Universe pp. 727-733

Adam Burrows

Genetic ablation reveals that the roof plate is essential for dorsal interneuron specification pp. 734-740

Kevin J. Lee, Paula Dietrich and Thomas M. Jessell

Origin of the Moon's orbital inclination from resonant disk interactions pp. 741-743

William R. Ward and Robin M. Canup

Preparing pure photon number states of the radiation field pp. 743-746

B. T. H. Varcoe, S. Brattke, M. Weidinger and H. Walther

Imaging the effects of individual zinc impurity atoms on superconductivity in Bi2Sr2CaCu2O8+δ pp. 746-750

S. H. Pan, E. W. Hudson, K. M. Lang, H. Eisaki, S. Uchida and J. C. Davis

High-efficiency fluorescent organic light-emitting devices using a phosphorescent sensitizer pp. 750-753

M. A. Baldo, M. E. Thompson and S. R. Forrest

Explanation for fracture spacing in layered materials pp. 753-756

T. Bai, D. D. Pollard and H. Gao

Temperature trends over the past five centuries reconstructed from borehole temperatures pp. 756-758

Shaopeng Huang, Henry N. Pollack and Po-Yu Shen

Effect of stream channel size on the delivery of nitrogen to the Gulf of Mexico pp. 758-761

Richard B. Alexander, Richard A. Smith and Gregory E. Schwarz

Producer–decomposer co-dependency influences biodiversity effects pp. 762-764

Shahid Naeem, Daniel R. Hahn and Gregor Schuurman

The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS pp. 764-769

James H. Millonig, Kathleen J. Millen and Mary E. Hatten

Forebrain peptides modulate sexually polymorphic vocal circuitry pp. 769-772

James L. Goodson and Andrew H. Bass

Mapping the conformational wave of acetylcholine receptor channel gating pp. 773-776

Claudio Grosman, Ming Zhou and Anthony Auerbach

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter pp. 776-781

Adriana Donovan, Alison Brownlie, Yi Zhou, Jennifer Shepard, Stephen J. Pratt, John Moynihan, Barry H. Paw, Anna Drejer, Bruce Barut, Agustin Zapata, Terence C. Law, Carlo Brugnara, Samuel E. Lux, Geraldine S. Pinkus, Jack L. Pinkus, Paul D. Kingsley, James Palis, Mark D. Fleming, Nancy C. Andrews and Leonard I. Zon

Interaction between Wnt and TGF-β signalling pathways during formation of Spemann's organizer pp. 781-785

Michiru Nishita, Minako K. Hashimoto, Souichi Ogata, Micheline N. Laurent, Naoto Ueno, Hiroshi Shibuya and Ken W. Y. Cho

Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis pp. 785-789

Sha Mi, Xinhua Lee, Xiang-ping Li, Geertruida M. Veldman, Heather Finnerty, Lisa Racie, Edward LaVallie, Xiang-Yang Tang, Philippe Edouard, Steve Howes, James C. Keith and John M. McCoy

naked cuticle encodes an inducible antagonist of Wnt signalling pp. 789-795

Wenlin Zeng, Keith A. Wharton, Judith A. Mack, Kevin Wang, Matthew Gadbaw, Kaye Suyama, Peter S. Klein and Matthew P. Scott

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase pp. 795-800

Shin-ichiro Imai, Christopher M. Armstrong, Matt Kaeberlein and Leonard Guarente

The structures of HslU and the ATP-dependent protease HslU–HslV pp. 800-805

Matthias Bochtler, Claudia Hartmann, Hyun Kyu Song, Gleb P. Bourenkov, Hans D. Bartunik and Robert Huber

Structure of the intact transactivation domain of the human papillomavirus E2 protein pp. 805-809

Alfred A. Antson, Julie E. Burns, Olga V. Moroz, David J. Scott, Cyril M. Sanders, Igor B. Bronstein, G. Guy Dodson, Keith S. Wilson and Norman J. Maitland

2000, volume 403, articles 6770

CERN claims first experimental creation of quark–gluon plasma pp. 581-581

Alison Abbott

Austria taken to court for inadequate laws on animal welfare pp. 582-582

Keith Nuthall

International science council names first female president pp. 582-582

Rex Dalton

Biotech companies attack NIH rules pp. 582-582

Paul Smaglik

NASA review leaves projects on launch pad pp. 583-583

Tony Reichhardt

Congress gets tough with gene therapy pp. 583-584

Paul Smaglik

Scientists reject blame for German genome shortfall pp. 584-584

Alison Abbott

Clinton's farewell gift to US science agencies pp. 585-585

Colin Macilwain, Tony Reichhardt and Paul Smaglik

Mostly winners — but the NIF must make do pp. 585-585

Colin Macilwain, Tony Reichhardt and Paul Smaglik

Stanford accelerator takes lead in race to quantify CP violation pp. 586-586

Colin Macilwain

Charm, not tact, aided pioneer in fight for physics pp. 586-587

Colin Macilwain

Sky's the limit as teams bid for NASA project pp. 587-587

Colin Macilwain

Proteins suggest form of their own database pp. 591-592

Marvin Cassman, Tony Hunter and Tony Pawson

Will cell alliance breed bureaucracy and leave contributors out? pp. 591-591

Stephen J. Haggarty and Miguel Ramalho-Santos

Will cell alliance breed bureaucracy and leave contributors out? pp. 591-591

Henry R. Bourne and Alfred G. Gilman

Debating controversies can enhance creativity pp. 592-592

Shi V. Liu

Time for an aspirin pp. 592-592

Marvin Minsky

The myth of well-funded German research pp. 592-592

Geoffrey A. Manley

Worth more dead than alive pp. 593-594

Harold A. Mooney

Population genetics revisited pp. 594-595

John Maynard Smith

Secrets, codes and decoders pp. 595-596

Charles H. Bennett

A compendium of Victorian culture pp. 596-596

Sophie Forgan

Laying down the law pp. 597-597

Vaclav Smil

Only connect pp. 599-599

Greg Egan

Guilt-by-association goes global pp. 601-602

Stephen Oliver

Dynamics of Jupiter's atmosphere pp. 603-605

Alvin Seiff

Images of lost sleep pp. 605-606

Jim Horne

Design by necessity pp. 606-607

Gregory A. Petsko

A Hox by any other name pp. 607-609

Denis Duboule

Conflicting arrows of time pp. 609-609

Peter T. Landsberg and James Vickers

Stirring the icy waters pp. 610-611

Charles R. Bentley

Which way is up? pp. 611-612

Mark Peifer and Ulrich Tepass

Stirring the blood pp. 612-612

David Jones

Flight restores fight in crickets pp. 613-613

Hans A. Hofmann and Paul A. Stevenson

A new model for protein stereospecificity pp. 614-615

Andrew D. Mesecar and Daniel E. Koshland

The ACE gene and muscle performance pp. 614-614

A. G. Williams, M. P. Rayson, M. Jubb, M. World, D. R. Woods, M. Hayward, J. Martin, S. E. Humphries and H. E. Montgomery

‘Ghost’ alleles of the Mauritius kestrel pp. 616-616

Jim J. Groombridge, Carl G. Jones, Michael W. Bruford and Richard A. Nichols

Directed evolution of new catalytic activity using the α/β-barrel scaffold pp. 617-622

Myriam M. Altamirano, Jonathan M. Blackburn, Cristina Aguayo and Alan R. Fersht

A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae pp. 623-627

Peter Uetz, Loic Giot, Gerard Cagney, Traci A. Mansfield, Richard S. Judson, James R. Knight, Daniel Lockshon, Vaibhav Narayan, Maithreyan Srinivasan, Pascale Pochart, Alia Qureshi-Emili, Ying Li, Brian Godwin, Diana Conover, Theodore Kalbfleisch, Govindan Vijayadamodar, Meijia Yang, Mark Johnston, Stanley Fields and Jonathan M. Rothberg

Observation of moist convection in Jupiter's atmosphere pp. 628-630

P. J. Gierasch, A. P. Ingersoll, D. Banfield, S. P. Ewald, P. Helfenstein, A. Simon-Miller, A. Vasavada, H. H. Breneman, D. A. Senske and Galileo Imaging Team

Moist convection as an energy source for the large-scale motions in Jupiter's atmosphere pp. 630-632

A. P. Ingersoll, P. J. Gierasch, D. Banfield, A. R. Vasavada and Galileo Imaging Team

Structure and bandgap closure in dense hydrogen pp. 632-635

Kurt A. Johnson and N. W. Ashcroft

Direct measurement of electrical transport through DNA molecules pp. 635-638

Danny Porath, Alexey Bezryadin, Simon de Vries and Cees Dekker

Non-destructive determination of local strain with 100-nanometre spatial resolution pp. 638-640

S. Di Fonzo, W. Jark, S. Lagomarsino, C. Giannini, L. De Caro, A. Cedola and M. Müller

Air entrapment in coatings by way of a tip-streaming meniscus pp. 641-643

P. G. Simpkins and V. J. Kuck

Water exchange between the subglacial Lake Vostok and the overlying ice sheet pp. 643-646

Martin J. Siegert, Ron Kwok, Christoph Mayer and Bryn Hubbard

Stable-isotope probing as a tool in microbial ecology pp. 646-649

Stefan Radajewski, Philip Ineson, Nisha R. Parekh and J. Colin Murrell

Ancestral chloroplast genome in Mesostigma viride reveals an early branch of green plant evolution pp. 649-652

Claude Lemieux, Christian Otis and Monique Turmel

Pattern recognition and active vision in chickens pp. 652-655

Marian Stamp Dawkins and Alan Woodington

Altered brain response to verbal learning following sleep deprivation pp. 655-657

Sean P. A. Drummond, Gregory G. Brown, J. Christian Gillin, John L. Stricker, Eric C. Wong and Richard B. Buxton

The organizer factors Chordin and Noggin are required for mouse forebrain development pp. 658-661

Daniel Bachiller, John Klingensmith, C. Kemp, J. A. Belo, R. M. Anderson, S. R. May, J. A. McMahon, A. P. McMahon, R. M. Harland, J. Rossant and E. M. De Robertis

Maintenance of functional equivalence during paralogous Hox gene evolution pp. 661-665

Joy M. Greer, John Puetz, Kirk R. Thomas and Mario R. Capecchi

The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences pp. 665-668

J. Parkhill, B. W. Wren, K. Mungall, J. M. Ketley, C. Churcher, D. Basham, T. Chillingworth, R. M. Davies, T. Feltwell, S. Holroyd, K. Jagels, A. V. Karlyshev, S. Moule, M. J. Pallen, C. W. Penn, M. A. Quail, M-A. Rajandream, K. M. Rutherford, A. H. M. van Vliet, S. Whitehead and B. G. Barrell

Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands pp. 669-672

Pavel I. Kitov, Joanna M. Sadowska, George Mulvey, Glen D. Armstrong, Hong Ling, Navraj S. Pannu, Randy J. Read and David R. Bundle

How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis pp. 672-676

Richard Glynne, Srinivas Akkaraju, James I. Healy, Jane Rayner, Christopher C. Goodnow and David H. Mack

Localization of apical epithelial determinants by the basolateral PDZ protein Scribble pp. 676-680

David Bilder and Norbert Perrimon

A tripeptide ‘anticodon’ deciphers stop codons in messenger RNA pp. 680-684

Koichi Ito, Makiko Uno and Yoshikazu Nakamura

2000, volume 403, articles 6769

Nuclear fusion without weapons testing pp. 469-469

Colin Macilwain

Livermore plans radical rescue for ‘mismanaged’ laser facility pp. 469-470

Colin Macilwain

Japan may allow human embryo stem-cell research pp. 470-470

David Cyrano

WWW project aims to address worldwide decline in amphibians pp. 471-472

Rex Dalton

Change of government bodes well for NZ science funding pp. 471-471

Peter Pockley

Anderson steps down from Wellcome over Oxford row pp. 472-472

Natasha Loder

Nossal named Australian of the Year pp. 472-472

Peter Pockley

Rules agreed over GM food exports pp. 473-474

Colin Macilwain

IBM joins genomics mapping consortium pp. 473-473

Declan Butler

German science begins to cure its historical amnesia pp. 474-475

Alison Abbott

Apathy rewards misconduct — and everybody suffers pp. 478-478

Herbert N. Arst

End of impact factors? pp. 478-478

John Brunstein

Nucleic acids revelation delayed by a sceptic pp. 478-478

Friedrich Katscher

Proteomics is getting easier in some ways… pp. 478-478

Joan L. Slonczewski

… and should be treated the same as genomics pp. 478-478

Jeffrey E. Segall

The decade of the sheep pp. 479-480

Anne McLaren

Dead branches on the tree of life pp. 480-481

David M. Irwin

Textiles, bridges, plastics and chips pp. 481-481

Gunhard Æ. Oravas

Cocktail-party gossip aplenty pp. 481-482

Jeanne Altmann

Science in culture pp. 482-482

John E. Thornes

Decline of the generalist pp. 483-483

Frederick Seitz

From Caribbean to Clementine pp. 485-485

Stephen Baxter

Fluff balls of fire pp. 487-488

Graham K. Hubler

Survey flights in honeybees pp. 488-489

Thomas Collett

Electrons in the looking glass pp. 489-491

Eric Heller

Gene expression in diagnosis pp. 491-492

Anton Berns

Alien invaders pp. 492-493

Peter D. Moore

The sting in a fractal tail pp. 493-495

Colin P. Stark and Marc Stieglitz

A predictor of pathology pp. 495-496

John C. Rothwell

Optical control of reactions pp. 496-497

Stuart A. Rice

Perfect dryness pp. 497-497

David Jones

Olivier Kahn (1943–99) pp. 498-498

Peter Day

Longevity record for deep-sea invertebrate pp. 499-500

Derk C. Bergquist, Frederick M. Williams and Charles R. Fisher

Mitochondria and the death of oocytes pp. 500-501

Gloria I. Perez, Alexander M. Trbovich, Roger G. Gosden and Jonathan L. Tilly

Demethylation of the zygotic paternal genome pp. 501-502

Wolfgang Mayer, Alain Niveleau, Jörn Walter, Reinald Fundele and Thomas Haaf

Mitochondria and the death of oocytes pp. 501-501

David C. Krakauer and Alex Mira

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling pp. 503-511

Ash A. Alizadeh, Michael B. Eisen, R. Eric Davis, Chi Ma, Izidore S. Lossos, Andreas Rosenwald, Jennifer C. Boldrick, Hajeer Sabet, Truc Tran, Xin Yu, John I. Powell, Liming Yang, Gerald E. Marti, Troy Moore, James Hudson, Lisheng Lu, David B. Lewis, Robert Tibshirani, Gavin Sherlock, Wing C. Chan, Timothy C. Greiner, Dennis D. Weisenburger, James O. Armitage, Roger Warnke, Ronald Levy, Wyndham Wilson, Michael R. Grever, John C. Byrd, David Botstein, Patrick O. Brown and Louis M. Staudt

Quantum mirages formed by coherent projection of electronic structure pp. 512-515

H. C. Manoharan, C. P. Lutz and D. M. Eigler

Experimental test of quantum nonlocality in three-photon Greenberger–Horne–Zeilinger entanglement pp. 515-519

Jian-Wei Pan, Dik Bouwmeester, Matthew Daniell, Harald Weinfurter and Anton Zeilinger

Ball lightning caused by oxidation of nanoparticle networks from normal lightning strikes on soil pp. 519-521

John Abrahamson and James Dinniss

Large-scale complementary integrated circuits based on organic transistors pp. 521-523

B. Crone, A. Dodabalapur, Y.-Y. Lin, R. W. Filas, Z. Bao, A. LaDuca, R. Sarpeshkar, H. E. Katz and W. Li

Fractal stream chemistry and its implications for contaminant transport in catchments pp. 524-527

James W. Kirchner, Xiahong Feng and Colin Neal

Rapid diffusive infiltration of sodium into partially molten peridotite pp. 527-530

Craig C. Lundstrom

Oxygen-isotope evidence for recycled crust in the sources of mid-ocean-ridge basalts pp. 530-534

John M. Eiler, Pierre Schiano, Nami Kitchen and Edward M. Stolper

Quality of the fossil record through time pp. 534-537

M. J. Benton, M. A. Wills and R. Hitchin

Ontogeny of orientation flight in the honeybee revealed by harmonic radar pp. 537-540

Elizabeth A. Capaldi, Alan D. Smith, Juliet L. Osborne, Susan E. Fahrbach, Sarah M. Farris, Donald R. Reynolds, Ann S. Edwards, Andrew Martin, Gene E. Robinson, Guy M. Poppy and Joseph R. Riley

Myoglobin-like aerotaxis transducers in Archaea and Bacteria pp. 540-544

Shaobin Hou, Randy W. Larsen, Dmitri Boudko, Charles W. Riley, Ece Karatan, Mike Zimmer, George W. Ordal and Maqsudul Alam

Motor disorder in Huntington's disease begins as a dysfunction in error feedback control pp. 544-549

Maurice A. Smith, Jason Brandt and Reza Shadmehr

A neuronal analogue of state-dependent learning pp. 549-553

D. E. Shulz, R. Sosnik, V. Ego, S. Haidarliu and E. Ahissar

Modulation of A-type potassium channels by a family of calcium sensors pp. 553-556

W. Frank An, Mark R. Bowlby, Maria Betty, Jie Cao, Huai-Ping Ling, Grace Mendoza, Joseph W. Hinson, Karen I. Mattsson, Brian W. Strassle, James S. Trimmer and Kenneth J. Rhodes

Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1 pp. 557-560

Ching-Kang Chen, Marie E. Burns, Wei He, Theodore G. Wensel, Denis A. Baylor and Melvin I. Simon

Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant pp. 560-564

Ji Ying Sze, Martin Victor, Curtis Loer, Yang Shi and Gary Ruvkun

Evidence for stabilizing selection in a eukaryotic enhancer element pp. 564-567

Michael Z. Ludwig, Casey Bergman, Nipam H. Patel and Martin Kreitman

Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins pp. 567-571

Balaji Prakash, Gerrit J. K. Praefcke, Louis Renault, Alfred Wittinghofer and Christian Herrmann

Alternative modular polyketide synthase expression controls macrolactone structure pp. 571-575

Yongquan Xue and David H. Sherman

Erratum The neurobiology of cognition pp. 575-575

M. James Nichols and William T. Newsome

2000, volume 403, articles 6768

Quality, not quantity, for UK PhDs? pp. 347-347

Natasha Loder

All parties keen to press on with Europe-based science website pp. 347-348

Declan Butler

Clinton proposes $2.8 billion increase in science funding pp. 349-349

Rex Dalton

Yale hopes a $500 million boost will raise research profile pp. 349-349

Paul Smaglik

NIH cancer researchers to get free access to ‘OncoMouse’ pp. 350-350

Paul Smaglik

Canadian biomedical collaboration keeps on growing pp. 350-350

David Spurgeon

Issue of patents on ‘Dolly’ technology stirs controversy pp. 351-352

Meredith Wadman

Ministries cooperate to plan Japanese genome centre pp. 351-351

David Cyrano

Top physicist quits Japan for US pp. 351-351

Robert Triendl

US survey reveals location of human tissue samples pp. 352-352

Colin Macilwain

India targets extra research funds pp. 352-352

K. S. Jayaraman

Head of US watchdog faces uncertain future pp. 353-353

Meredith Wadman

Top UK epidemiologist suspended after complaints pp. 353-353

Natasha Loder

Cell contamination leads to inaccurate data: we must take action now pp. 356-356

G. N. Stacey

Mitchell saw the new vista, if not the details pp. 356-356

Bo G. Malmström

Give credit where it's due (not to me, this time) pp. 356-356

Reed B. Wickner

Science moves to centre stage pp. 357-359

Ana Padilla and Ian Gibson

Instincts for the past tense pp. 361-362

David Poeppel

Why not knot right? pp. 362-362

Gregory Buck

Powering the planet pp. 363-363

Michael Grätzel

An evolutionary odyssey pp. 363-364

Jean-Jacques Hublin

Science in culture pp. 364-364

Martin Kemp

New approaches to old age pp. 365-365

Leonard Hayflick

Pluto story pp. 367-367

Robert Silverberg

Nogo in nerve regeneration pp. 369-370

J. L. Goldberg and B. A. Barres

Out of Africa pp. 370-371

Frank Oldfield

Harvesting sunlight safely pp. 371-373

Barbara Demmig-Adams and William W. Adams

Democracy on the rocks pp. 373-373

Bruce W. D. Yardley

One photon seen by one electron pp. 374-375

Leo Kouwenhoven

Rice, microbes and methane pp. 375-377

Joshua Schimel

Jets from a singular surface pp. 377-378

Michael P. Brenner

Evolutionary psychology meets g pp. 378-379

N. J. Mackintosh

Volcanic action at Axial Seamount pp. 379-380

Earl Davis

No more feelings pp. 380-380

David Jones

Energy for microbial life on Europa pp. 381-382

Christopher F. Chyba

A function for guttural pouches in the horse pp. 382-383

Keith E. Baptiste, Jonathan M. Naylor, Jeremy Bailey, Ernest M. Barber, Klass Post and Jim Thornhill

Inhibitor of neurite outgrowth in humans pp. 383-384

Rabinder Prinjha, Stephen E. Moore, Mary Vinson, Sian Blake, Rachel Morrow, Gary Christie, David Michalovich, David L. Simmons and Frank S. Walsh

Creating the narrowest carbon nanotubes pp. 384-384

L. F. Sun, S. S. Xie, W. Liu, W. Y. Zhou, Z. Q. Liu, D. S. Tang, G. Wang and L. X. Qian

Nodal signalling in vertebrate development pp. 385-389

Alexander F. Schier and Michael M. Shen

A pigment-binding protein essential for regulation of photosynthetic light harvesting pp. 391-395

Xiao-Ping Li, Olle Björkman, Connie Shih, Arthur R. Grossman, Magnus Rosenquist, Stefan Jansson and Krishna K. Niyogi

Probing bulk states of correlated electron systems by high-resolution resonance photoemission pp. 396-398

A. Sekiyama, T. Iwasaki, K. Matsuda, Y. Saitoh, Y. Ônuki and S. Suga

Dynamic instabilities and memory effects in vortex matter pp. 398-401

Y. Paltiel, E. Zeldov, Y. N. Myasoedov, H. Shtrikman, S. Bhattacharya, M. J. Higgins, Z. L. Xiao, E. Y. Andrei, P. L. Gammel and D. J. Bishop

Singularity dynamics in curvature collapse and jet eruption on a fluid surface pp. 401-404

Benjamin W. Zeff, Benjamin Kleber, Jay Fineberg and Daniel P. Lathrop

A single-photon detector in the far-infrared range pp. 405-407

S. Komiyama, O. Astafiev, V. Antonov, T. Kutsuwa and H. Hirai

Efficient organic photovoltaic diodes based on doped pentacene pp. 408-410

J. H. Schön, Ch. Kloc, E. Bucher and B. Batlogg

Rainfall and drought in equatorial east Africa during the past 1,100 years pp. 410-414

Dirk Verschuren, Kathleen R. Laird and Brian F. Cumming

Precise climate monitoring using complementary satellite data sets pp. 414-416

Frank J. Wentz and Matthias Schabel

The Pleistocene serpent Wonambi and the early evolution of snakes pp. 416-420

John D. Scanlon and Michael S. Y. Lee

Stimulation by ammonium-based fertilizers of methane oxidation in soil around rice roots pp. 421-424

Paul L. E. Bodelier, Peter Roslev, Thilo Henckel and Peter Frenzel

Activin- and Nodal-related factors control antero–posterior patterning of the zebrafish embryo pp. 425-428

Bernard Thisse, Christopher V. E. Wright and Christine Thisse

Separable processing of consonants and vowels pp. 428-430

Alfonso Caramazza, Doriana Chialant, Rita Capasso and Gabriele Miceli

Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion pp. 430-434

J. M. Delfs, Y. Zhu, J. P. Druhan and G. Aston-Jones

Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1 pp. 434-439

Maio S. Chen, Andrea B. Huber, Marjan E. van der Haar, Marcus Frank, Lisa Schnell, Adrian A. Spillmann, Franziska Christ and Martin E. Schwab

Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein pp. 439-444

Tadzia GrandPré, Fumio Nakamura, Timothy Vartanian and Stephen M. Strittmatter

Torque-generating units of the flagellar motor of Escherichia coli have a high duty ratio pp. 444-447

William S. Ryu, Richard M. Berry and Howard C. Berg

The DExH protein NPH-II is a processive and directional motor for unwinding RNA pp. 447-451

Eckhard Jankowsky, Christian H. Gross, Stewart Shuman and Anna Marie Pyle

DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination pp. 451-456

Clifford D. Mol, Tadahide Izumi, Sankar Mitra and John A. Tainer

Design of single-layer β-sheets without a hydrophobic core pp. 456-460

Shohei Koide, Xiaolin Huang, Karl Link, Akiko Koide, Zimei Bu and Donald M. Engelman

Passing the baton? pp. 463-463

Brendan Horton

Bioengineering programmes rise to meet the challenge of a young science pp. 464-466

Brendan Horton

Exploring the territory in tissue engineering pp. 464-464

Potter Wickware

Creative fusion of many minds pp. 464-464

Brendan Horton

Progress from a fragile start pp. 466-466

Potter Wickware

Insiders advise on first steps to a career pp. 466-466

Potter Wickware

2000, volume 403, articles 6767

Celera genome licensing terms spark concerns over ‘monopoly’ pp. 231-231

Declan Butler and Paul Smaglik

Merger of Glaxo Wellcome and SmithKline Beecham creates pharmaceutical giant pp. 232-232

Alison Abbott

NASA ponders termination of gamma-ray observatory pp. 232-232

Tony Reichhardt

Global-warming sceptics left out in the cold pp. 233-233

Colin Macilwain

Diversity convention in the balance pp. 233-233

Colin Macilwain

DIY microarrayers promise DNA chips with everything pp. 234-234

Rex Dalton

Australian university chiefs attack plans for research funding pp. 234-234

Peter Pockley

Dutch institute forced to respond to crisis in recruitment of postdoctoral researchers pp. 235-235

Natasha Loder

Appointment of UK food standards chief under fire pp. 235-235

Natasha Loder

Mouse geneticists call for unified rules of exchange pp. 236-236

Alison Abbott

Business lobby set to take EPA to court over data access pp. 236-236

Colin Macilwain

NIH under fire over gene-therapy trials… pp. 237-237

Meredith Wadman

…as panel seeks help for trial host nations pp. 237-237

Paul Smaglik

There's a place for the theory of everything pp. 241-242

John Ellis

Local data are vital to worldwide conservation pp. 241-241

Jon Paul Rodríguez, Gillian Ashenfelter, Franklin Rojas-Suárez, Juan Javier García Fernández, Luis Suárez and Andrew P. Dobson

ECT damage is easy to find if you look for it pp. 242-242

Peter Sterling

Full effects of oil rigs on corals are not yet known pp. 242-242

J. M. Roberts

Cover adds fuel to the fire in evolution battle pp. 242-242

Gary C. Harris and Martina Königer

Cover adds fuel to the fire in evolution battle pp. 242-242

Editor

Seeking the great transition pp. 243-245

Gretchen C. Daily and Brian H. Walker

Is the sky made from pi? pp. 247-248

Frank Wilczek

Arctic antics pp. 248-249

Douglas Palmer

The Osler magic revisited pp. 249-250

W. F. Bynum

Seeing the world in a mote of dust pp. 250-250

Ralph Lewin

Tycho and the ton of gold pp. 251-251

Owen Gingerich

Cognitive ability and the light bulb pp. 253-253

Brian Aldiss

A central control for cell growth pp. 255-256

Alan J. Whitmarsh and Roger J. Davis

Engineering decoherence pp. 256-257

Wolfgang P. Schleich

Finding the lost target pp. 257-259

Martin E. Schwab

Better budgets for methyl halides? pp. 260-261

James H. Butler

Protamine wars pp. 261-263

Andrew G. Clark and Alberto Civetta

States of non-mind pp. 263-263

David Jones

Erratum: A tale of ends pp. 263-263

Victoria Lundblad

Robert A. Swanson (1947–99) pp. 264-264

David V. Goeddel and Arthur D. Levinson

Ultrasonic hearing in nocturnal butterflies pp. 265-266

Jayne E. Yack and James H. Fullard

Atomic structure of the quasicrystal Al72Ni20Co8 pp. 266-267

Yanfa Yan and Stephen J. Pennycook

Circadian clocks limited by noise pp. 267-268

Naama Barkai and Stanislas Leibler

Atomic structure of the quasicrystal Al72Ni20Co8 pp. 267-267

Paul J. Steinhardt, H.-C. Jeong, K. Saitoh, M. Tanaka, E. Abe and A. P. Tsai

Decoherence of quantum superpositions through coupling to engineered reservoirs pp. 269-273

C. J. Myatt, B. E. King, Q. A. Turchette, C. A. Sackett, D. Kielpinski, W. M. Itano, C. Monroe and D. J. Wineland

Direct protein–protein coupling enables cross-talk between dopamine D5 and γ-aminobutyric acid A receptors pp. 274-280

Fang Liu, Qi Wan, Zdenek B. Pristupa, Xian-Min Yu, Yu Tian Wang and Hyman B. Niznik

Polarization rotation mechanism for ultrahigh electromechanical response in single-crystal piezoelectrics pp. 281-283

Huaxiang Fu and Ronald E. Cohen

Dynamics of supercooled water in confined geometry pp. 283-286

R. Bergman and J. Swenson

Molecular imprinting of bulk, microporous silica pp. 286-289

Alexander Katz and Mark E. Davis

Biomimetic synthesis of ordered silica structures mediated by block copolypeptides pp. 289-292

Jennifer N. Cha, Galen D. Stucky, Daniel E. Morse and Timothy J. Deming

Natural methyl bromide and methyl chloride emissions from coastal salt marshes pp. 292-295

Robert C. Rhew, Benjamin R. Miller and Ray F. Weiss

A strong source of methyl chloride to the atmosphere from tropical coastal land pp. 295-298

Y. Yokouchi, Y. Noijiri, L. A. Barrie, D. Toom-Sauntry, T. Machida, Y. Inuzuka, H. Akimoto, H.-J. Li, Y. Fujinuma and Shuhei Aoki

Halocarbons produced by natural oxidation processes during degradation of organic matter pp. 298-301

F. Keppler, R. Eiden, V. Niedan, J. Pracht and H. F. Schöler

Annual fluxes of carbon from deforestation and regrowth in the Brazilian Amazon pp. 301-304

R. A. Houghton, D. L. Skole, Carlos A. Nobre, J. L. Hackler, K. T. Lawrence and W H. Chomentowski

Rapid evolution of male reproductive genes in the descent of man pp. 304-309

Gerald J. Wyckoff, Wen Wang and Chung-I Wu

Voice-selective areas in human auditory cortex pp. 309-312

Pascal Belin, Robert J. Zatorre, Philippe Lafaille, Pierre Ahad and Bruce Pike

Functional regeneration of sensory axons into the adult spinal cord pp. 312-316

Matt S. Ramer, John V. Priestley and Stephen B. McMahon

Glutamate release in severe brain ischaemia is mainly by reversed uptake pp. 316-321

David J. Rossi, Takeo Oshima and David Attwell

Blocker protection in the pore of a voltage-gated K+ channel and its structural implications pp. 321-325

Donato del Camino, Miguel Holmgren, Yi Liu and Gary Yellen

KIR expression on self-reactive CD8+ T cells is controlled by T-cell receptor engagement pp. 325-328

Bertrand Huard and Lars Karlsson

Regulation of carbamoyl phosphate synthetase by MAP kinase pp. 328-332

Lee M. Graves, Hedeel I. Guy, Piotr Kozlowski, Min Huang, Eduardo Lazarowski, R. Marshall Pope, Matthew A. Collins, Erik N. Dahlstrand, H. Shelton Earp and David R. Evans

The joining of ribosomal subunits in eukaryotes requires eIF5B pp. 332-335

Tatyana V. Pestova, Ivan B. Lomakin, Joon H. Lee, Sang Ki Choi, Thomas E. Dever and Christopher U. T. Hellen

A synthetic oscillatory network of transcriptional regulators pp. 335-338

Michael B. Elowitz and Stanislas Leibler

Construction of a genetic toggle switch in Escherichia coli pp. 339-342

Timothy S. Gardner, Charles R. Cantor and James J. Collins

2000, volume 403, articles 6766

Celera turns to public genome data to speed up endgame pp. 119-119

Paul Smaglik and Declan Butler

...as Internet fervour hits genomics pp. 119-120

David Dickson

Inadequate optics 'threat to US laser facility' pp. 120-120

Colin Macilwain

Bell Labs win superconductivity patent pp. 121-122

Colin Macilwain

UK discussed ban on foreign job ads in 1960s pp. 121-121

Natasha Loder

Genetics takes off in Naples as institute moves south pp. 122-122

Alison Abbott

NIH seeks funding for neuroscience centre … pp. 123-123

Paul Smaglik

… as lobbyists anticipate more money for all pp. 123-123

Colin Macilwain and Paul Smaglik

Greenwich ‘could be symbolic timekeeper for electronic era’ pp. 124-124

Natasha Loder

Brussels research chief backs European website proposal pp. 124-124

Declan Butler

Japanese support biotech start-ups pp. 124-124

Robert Triendl

Biologists flock to ‘evo-devo’ in a quest to read the recipes of life pp. 125-125

Rex Dalton

Global bodies won't save the environment: it needs grass-roots efforts … pp. 129-129

Ignacio H. Chapela

… or should private enterprise take over? pp. 129-129

Matthew Brown and Donald R. Leal

Proteins and the naked truth about e-commerce pp. 129-130

Dattatray Parasnis

Proteins and the naked truth about e-commerce pp. 130-130

Alex May

Proteins and the naked truth about e-commerce pp. 130-130

Alex May

EPA error risked halving India's rice harvest pp. 130-130

E. S. R. Gopal

Wherever HIV originated, polio vaccine is safe now pp. 130-130

Ka-Wing Wong

East German academics faced unfair hurdles pp. 130-130

Bernd Legler and Guy Moore

Sowing nuclear misconceptions pp. 131-133

Kurt Gottfried

The truth is in here pp. 135-136

Henry Gee

Simplicity out of complexity pp. 136-136

Jonathan R. Ellis

Of pigs, poultry and permafrost pp. 137-138

David A. J. Tyrrell

Integrals of disease pp. 138-138

Graham F. Medley

Science in culture pp. 138-138

Alison Abbott

Positioning the goalposts pp. 139-139

John Maddox

Deep Ice and DNA languages pp. 141-141

Greg Bear

DNA computing on a chip pp. 143-144

Mitsunori Ogihara and Animesh Ray

From insects to microvehicles pp. 144-145

Robin Wootton

Eyes wide shut pp. 145-148

David Jewitt

Gateway to the chloroplast pp. 148-149

Kenneth Cline

A tale of ends pp. 149-151

Victoria Lundblad

More spins for protons pp. 151-151

Sarah Tomlin

Jumping between liquid states pp. 151-152

Paul McMillan

Fossil fish up for election pp. 152-153

Meemann Chang

Internal model visualized pp. 153-154

Masao Ito

Coal, air, fire and water pp. 154-154

David Jones

A pygostyle from a non-avian theropod pp. 155-156

Rinchen Barsbold, Philip J. Currie, Nathan P. Myhrvold, Halszka Osmólska, Khishigjaw Tsogtbaatar and Mahito Watabe

Tall men have more reproductive success pp. 156-156

B. Pawlowski, R. I. M. Dunbar and A. Lipowicz

Eel fat stores are enough to reach the Sargasso pp. 156-157

Vincent J. T. van Ginneken and Guido E. E. J. M. van den Thillart

Children learn an untaught rule of spelling pp. 157-158

Peter Bryant, Terezinha Nunes and Rowena Snaith

Rapid chromosomal evolution in island mice pp. 158-158

Janice Britton-Davidian, Josette Catalan, Maria da Graça Ramalhinho, Guila Ganem, Jean-Christophe Auffray, Ruben Capela, Manuel Biscoito, Jeremy B. Searle and Maria da Luz Mathias

MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans pp. 159-164

Shawn Ahmed and Jonathan Hodgkin

A reduced estimate of the number of kilometre-sized near-Earth asteroids pp. 165-166

David Rabinowitz, Eleanor Helin, Kenneth Lawrence and Steven Pravdo

Measurement of the spatial coherence of a trapped Bose gas at the phase transition pp. 166-170

I. Bloch, T. W. Hänsch and T. Esslinger

A first-order liquid–liquid phase transition in phosphorus pp. 170-173

Yoshinori Katayama, Takeshi Mizutani, Wataru Utsumi, Osamu Shimomura, Masaaki Yamakata and Ken-ichi Funakoshi

Nanoscopic channel lattices with controlled anisotropic wetting pp. 173-175

M. Gleiche, L. F. Chi and H. Fuchs

DNA computing on surfaces pp. 175-179

Qinghua Liu, Liman Wang, Anthony G. Frutos, Anne E. Condon, Robert M. Corn and Lloyd M. Smith

Evidence for enhanced mixing over rough topography in the abyssal ocean pp. 179-182

J. R. Ledwell, E. T. Montgomery, K. L. Polzin, L. C. St. Laurent, R. W. Schmitt and J. M. Toole

Osmotic generation of ‘anomalous’ fluid pressures in geological environments pp. 182-184

C. E. Neuzil

The most primitive osteichthyan braincase? pp. 185-188

Alison M. Basden, Gavin C. Young, Michael I. Coates and Alex Ritchie

Molecular evidence regarding the origin of echolocation and flight in bats pp. 188-192

Emma C. Teeling, Mark Scally, Diana J. Kao, Michael L. Romagnoli, Mark S. Springer and Michael J. Stanhope

Human cerebellar activity reflecting an acquired internal model of a new tool pp. 192-195

Hiroshi Imamizu, Satoru Miyauchi, Tomoe Tamada, Yuka Sasaki, Ryousuke Takino, Benno Pütz, Toshinori Yoshioka and Mitsuo Kawato

A constitutively open potassium channel formed by KCNQ1 and KCNE3 pp. 196-199

Björn C. Schroeder, Siegfried Waldegger, Susanne Fehr, Markus Bleich, Richard Warth, Rainer Greger and Thomas J. Jentsch

Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages pp. 199-203

Célio G. Freire- de-Lima, Danielle O. Nascimento, Milena B. P. Soares, Patricia T. Bozza, Hugo C. Castro-Faria-Neto, Fernando G. de Mello, George A. DosReis and Marcela F. Lopes

The major protein import receptor of plastids is essential for chloroplast biogenesis pp. 203-207

Jörg Bauer, Kunhua Chen, Andreas Hiltbunner, Ernst Wehrli, Monika Eugster, Danny Schnell and Felix Kessler

Interferon-γ elicits arteriosclerosis in the absence of leukocytes pp. 207-211

George Tellides, Denis A. Tereb, Nancy C. Kirkiles-Smith, Richard W. Kim, Jean H. Wilson, Jeffrey S. Schechner, Marc I. Lorber and Jordan S. Pober

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b pp. 211-216

Kurt Bachmaier, Connie Krawczyk, Ivona Kozieradzki, Young-Yun Kong, Takehiko Sasaki, Antonio Oliveira-dos-Santos, Sanjeev Mariathasan, Dennis Bouchard, Andrew Wakeham, Annick Itie, Jenny Le, Pamela S. Ohashi, Ildiko Sarosi, Hiroshi Nishina, Stan Lipkowitz and Josef M. Penninger

Cbl-b regulates the CD28 dependence of T-cell activation pp. 216-220

Yungping J. Chiang, Hemanta K. Kole, Karen Brown, Mayumi Naramura, Shigetomo Fukuhara, Ren-Ju Hu, Ihn Kyung Jang, J. Silvio Gutkind, Ethan Shevach and Hua Gu

Measurement of thermal contribution to photoreceptor sensitivity pp. 220-223

Ari Koskelainen, Petri Ala-Laurila, Nanna Fyhrquist and Kristian Donner

Bioorganic synthesis of lipid-modified proteins for the study of signal transduction pp. 223-226

Benjamin Bader, Karsten Kuhn, David J. Owen, Herbert Waldmann, Alfred Wittinghofer and Jürgen Kuhlmann

2000, volume 403, articles 6765

Europe lifts patent embargo on transgenic plants and animals… pp. 3-3

Quirin Schiermeier and David Dickson

…as US tightens up on ‘speculative’ claims pp. 3-3

Paul Smaglik

Big gains for biology and IT in Japanese science budget pp. 4-4

Asako Saegusa

Genomics companies boom on New York stock exchange pp. 4-4

Paul Smaglik

US politicians have fallen in love with basic research pp. 5-6

Colin Macilwain

The role of science is to illuminate political choices, not enforce them pp. 6-7

Declan Butler

Japan's scientists must learn to take action pp. 7-8

David Swinbanks

I have reported on astonishing achievements in times of hardship pp. 8-9

Alison Abbott

If knowledge is king, we may need a republican revolution pp. 9-9

David Dickson

Do we need a huge new centre to annotate the human genome? pp. 12-12

Jean-Michel Claverie

How nature itself uses genetic modification pp. 12-12

Anthony Trewavas and Christopher Leaver

Millennial highlights pp. 13-16

J. L. Heilbron and W. F. Bynum

The waning of the Golden Age pp. 17-19

Walter Gratzer

Beneficent squid pp. 19-19

Tomoyuki Takahashi

Medicine's least respectable branch? pp. 19-20

Dylan Evans

In retrospect: chosen by David Jones pp. 20-20

David Jones

Making waves in physics pp. 21-21

Michael Berry

How science saved the world pp. 23-23

Kim Stanley Robinson

Optics adapt to the whole sky pp. 25-26

Brent Ellerbroek and François Rigaut

Living on the edge pp. 26-29

Thomas Brooks

Caspases find a new place to hide pp. 29-30

Huseyin Mehmet

A bright future for dark matter pp. 30-31

Brad Hansen

Taking the temperature of slabs pp. 31-34

Stephen H. Kirby

Telomeric tethers pp. 34-35

Wai-Hong Tham and Virginia A. Zakian

Taking the squeeze off sperm pp. 35-35

Tim Lincoln

Durable catalysts for cleaner air pp. 35-36

Jon G. McCarty

Depth of insight pp. 36-36

David Jones

Marine iguanas shrink to survive El Niño pp. 37-38

Martin Wikelski and Corinna Thom

Biogeography of the Indonesian coelacanths pp. 38-38

H. Fricke, K. Hissmann, J. Schauer, M. Erdmann, M. K. Moosa and R. Plante

Extrapolating movement without retinal motion pp. 38-39

John Schlag, Rick H. Cai, Andrews Dorfman, Ali Mohempour and Madeleine Schlag-Rey

Numerical memory span in a chimpanzee pp. 39-40

Nobuyuki Kawai and Tetsuro Matsuzawa

Explaining the T-wave shape in the ECG pp. 40-40

Diego di Bernardo and Alan Murray

The language of covalent histone modifications pp. 41-45

Brian D. Strahl and C. David Allis

Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor pp. 46-53

Melanie J. Bennett, José A. Lebrón and Pamela J. Bjorkman

Adaptive-optics corrections available for the whole sky pp. 54-56

Roberto Ragazzoni, Enrico Marchetti and Gianpaolo Valente

Infrared spectrum of an extremely cool white-dwarf star pp. 57-59

S. T. Hodgkin, B. R. Oppenheimer, N. C. Hambly, R. F. Jameson, S. J. Smartt and I. A. Steele

Tunnelling between the edges of two lateral quantum Hall systems pp. 59-61

W. Kang, H. L. Stormer, L. N. Pfeiffer, K. W. Baldwin and K. W. West

Magnetic trapping of neutrons pp. 62-64

P. R. Huffman, C. R. Brome, J. S. Butterworth, K. J. Coakley, M. S. Dewey, S. N. Dzhosyuk, R. Golub, G. L. Greene, K. Habicht, S. K. Lamoreaux, C. E. H. Mattoni, D. N. McKinsey, F. E. Wietfeldt and J. M. Doyle

Reverse microemulsion synthesis of nanostructured complex oxides for catalytic combustion pp. 65-67

Andrey J. Zarur and Jackie Y. Ying

Forecasting Andean rainfall and crop yield from the influence of El Niño on Pleiades visibility pp. 68-71

Benjamin S. Orlove, John C. H. Chiang and Mark A. Cane

Channelized fluid flow in oceanic crust reconciles heat-flow and permeability data pp. 71-74

A. T. Fisher and K. Becker

A highly unsaturated fatty acid predicts carbon transfer between primary producers and consumers pp. 74-77

Dörthe C. Müller-Navarra, Michael T. Brett, Anne M. Liston and Charles R. Goldman

The Santa Barbara Basin is a symbiosis oasis pp. 77-80

Joan M. Bernhard, Kurt R. Buck, Mark A. Farmer and Samuel S. Bowser

Mortality of sea lions along the central California coast linked to a toxic diatom bloom pp. 80-84

Christopher A. Scholin, Frances Gulland, Gregory J. Doucette, Scott Benson, Mark Busman, Francisco P. Chavez, Joe Cordaro, Robert DeLong, Andrew De Vogelaere, James Harvey, Martin Haulena, Kathi Lefebvre, Tom Lipscomb, Susan Loscutoff, Linda J. Lowenstine, Roman Marin, Peter E. Miller, William A. McLellan, Peter D. R. Moeller, Christine L. Powell, Teri Rowles, Paul Silvagni, Mary Silver, Terry Spraker, Vera Trainer and Frances M. Van Dolah

Dynamic biogeography and conservation of endangered species pp. 84-86

Rob Channell and Mark V. Lomolino

Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors pp. 86-89

K. Mulryan, D. P. Gitterman, C. J. Lewis, C. Vial, B. J. Leckie, A. L. Cobb, J. E. Brown, E. C. Conley, G. Buell, C. A. Pritchard and R. J. Evans

Turning of nerve growth cones induced by localized increases in intracellular calcium ions pp. 89-93

James Q. Zheng

Calcium signalling in the guidance of nerve growth by netrin-1 pp. 93-98

Kyonsoo Hong, Makoto Nishiyama, John Henley, Marc Tessier-Lavigne and Mu-ming Poo

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β pp. 98-103

Toshiyuki Nakagawa, Hong Zhu, Nobuhiro Morishima, En Li, Jin Xu, Bruce A. Yankner and Junying Yuan

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase pp. 103-108

Antonio Rossi, Pankaj Kapahi, Gioacchino Natoli, Takayuki Takahashi, Yi Chen, Michael Karin and M. Gabriella Santoro

Nuclear pore complexes in the organization of silent telomeric chromatin pp. 108-112

Vincent Galy, Jean-Christophe Olivo-Marin, Harry Scherthan, Valerie Doye, Nadia Rascalou and Ulf Nehrbass

Three-dimensional structure of the ion-coupled transport protein NhaA pp. 112-115

Karen A. Williams