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2018, volume 556, articles 7702

A lab co-op helps young faculty members to thrive pp. 409-409

Rebecca Heald

Clear signs of global warming will hit poorer countries first pp. 415-416

Quirin Schiermeier

Scientists’ early grant success fuels further funding pp. 416-417

Holly Else

US government considers charging for popular Earth-observing data pp. 417-418

Gabriel Popkin

Rent increase hits Europe’s drug regulator before Brexit move pp. 418-418

Inga Vesper

Mars probe poised to solve red planet’s methane mystery pp. 419-419

Nisha Gaind

Flu virus finally sequenced in its native form pp. 420-420

Ewen Callaway

Can the world kick its fossil-fuel addiction fast enough? pp. 422-425

Jeff Tollefson

Is ‘friendly fire’ in the brain provoking Alzheimer’s disease? pp. 426-428

Alison Abbott

The ethics of experimenting with human brain tissue pp. 429-432

Nita A. Farahany, Henry T. Greely, Steven Hyman, Christof Koch, Christine Grady, Sergiu P. Pașca, Nenad Sestan, Paola Arlotta, James L. Bernat, Jonathan Ting, Jeantine E. Lunshof, Eswar P. R. Iyer, Insoo Hyun, Beatrice H. Capestany, George M. Church, Hao Huang and Hongjun Song

Where the wild tales are: how stories teach kids to nurture nature pp. 434-435

S. F. Said

A visceral history of dinosaurs, the world through the nose of a dog and the psychological secrets of the plot twist: Books in brief pp. 435-435

Barbara Kiser

Order must spring from chaos in Italian research pp. 436-436

Gerry Melino

Geoengineering might speed glacier melt pp. 436-436

Twila A. Moon

Canadian cod comeback derailed pp. 436-436

Sherrylynn Rowe and George A. Rose

Make codes for research integrity practical pp. 436-436

Maura Hiney

Cap drug prices with policy – here’s how pp. 436-436

Leah Cairns

Classic reaction re-engineered through molecular face recognition pp. 438-439

Tobias Morack and Ryan Gilmour

A broader look at adolescents with perinatal HIV pp. 439-440

Patricia M. Flynn

Shrimp cause a stir pp. 440-440

Henry Gee

Organoids reveal cancer dynamics pp. 441-442

Calvin J. Kuo and Christina Curtis

Transition states that allow cancer to spread pp. 442-444

Erik W. Thompson and Shivashankar H. Nagaraj

Entangled vibrations in mechanical oscillators pp. 444-445

Andrew Armour

Hunger is a gatekeeper of pain in the brain pp. 445-446

Alexey Ponomarenko and Tatiana Korotkova

Quaternary stereocentres via an enantioconvergent catalytic SN1 reaction pp. 447-451

Alison E. Wendlandt, Prithvi Vangal and Eric N. Jacobsen

Renewing Felsenstein’s phylogenetic bootstrap in the era of big data pp. 452-456

F. Lemoine, J.-B. Domelevo Entfellner, E. Wilkinson, D. Correia, M. Dávila Felipe, T. Oliveira and O. Gascuel

Intra-tumour diversification in colorectal cancer at the single-cell level pp. 457-462

Sophie F. Roerink, Nobuo Sasaki, Henry Lee-Six, Matthew D. Young, Ludmil B. Alexandrov, Sam Behjati, Thomas J. Mitchell, Sebastian Grossmann, Howard Lightfoot, David A. Egan, Apollo Pronk, Niels Smakman, Joost Gorp, Elizabeth Anderson, Stephen J. Gamble, Chris Alder, Marc Wetering, Peter J. Campbell, Michael R. Stratton and Hans Clevers

Identification of the tumour transition states occurring during EMT pp. 463-468

Ievgenia Pastushenko, Audrey Brisebarre, Alejandro Sifrim, Marco Fioramonti, Tatiana Revenco, Soufiane Boumahdi, Alexandra Van Keymeulen, Daniel Brown, Virginie Moers, Sophie Lemaire, Sarah De Clercq, Esmeralda Minguijón, Cédric Balsat, Youri Sokolow, Christine Dubois, Florian De Cock, Samuel Scozzaro, Federico Sopena, Angel Lanas, Nicky D’Haene, Isabelle Salmon, Jean-Christophe Marine, Thierry Voet, Panagiota A. Sotiropoulou and Cédric Blanpain

A massive core for a cluster of galaxies at a redshift of 4.3 pp. 469-472

T. B. Miller, S. C. Chapman, M. Aravena, M. L. N. Ashby, C. C. Hayward, J. D. Vieira, A. Weiß, A. Babul, M. Béthermin, C. M. Bradford, M. Brodwin, J. E. Carlstrom, Chian-Chou Chen, D. J. M. Cunningham, C. Breuck, A. H. Gonzalez, T. R. Greve, J. Harnett, Y. Hezaveh, K. Lacaille, K. C. Litke, J. Ma, M. Malkan, D. P. Marrone, W. Morningstar, E. J. Murphy, D. Narayanan, E. Pass, R. Perry, K. A. Phadke, D. Rennehan, K. M. Rotermund, J. Simpson, J. S. Spilker, J. Sreevani, A. A. Stark, M. L. Strandet and A. L. Strom

Remote quantum entanglement between two micromechanical oscillators pp. 473-477

Ralf Riedinger, Andreas Wallucks, Igor Marinković, Clemens Löschnauer, Markus Aspelmeyer, Sungkun Hong and Simon Gröblacher

Stabilized entanglement of massive mechanical oscillators pp. 478-482

C. F. Ockeloen-Korppi, E. Damskägg, J.-M. Pirkkalainen, M. Asjad, A. A. Clerk, F. Massel, M. J. Woolley and M. A. Sillanpää

Low-loss plasmon-assisted electro-optic modulator pp. 483-486

Christian Haffner, Daniel Chelladurai, Yuriy Fedoryshyn, Arne Josten, Benedikt Baeuerle, Wolfgang Heni, Tatsuhiko Watanabe, Tong Cui, Bojun Cheng, Soham Saha, Delwin L. Elder, Larry. R. Dalton, Alexandra Boltasseva, Vladimir M. Shalaev, Nathaniel Kinsey and Juerg Leuthold

Earthquake-induced transformation of the lower crust pp. 487-491

Bjørn Jamtveit, Yehuda Ben-Zion, François Renard and Håkon Austrheim

Global warming transforms coral reef assemblages pp. 492-496

Terry P. Hughes, James T. Kerry, Andrew H. Baird, Sean R. Connolly, Andreas Dietzel, C. Mark Eakin, Scott F. Heron, Andrew S. Hoey, Mia O. Hoogenboom, Gang Liu, Michael J. McWilliam, Rachel J. Pears, Morgan S. Pratchett, William J. Skirving, Jessica S. Stella and Gergely Torda

Vertically migrating swimmers generate aggregation-scale eddies in a stratified column pp. 497-500

Isabel A. Houghton, Jeffrey R. Koseff, Stephen G. Monismith and John O. Dabiri

Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis pp. 501-504

Monika Bambouskova, Laurent Gorvel, Vicky Lampropoulou, Alexey Sergushichev, Ekaterina Loginicheva, Kendall Johnson, Daniel Korenfeld, Mary Elizabeth Mathyer, Hyeryun Kim, Li-Hao Huang, Dustin Duncan, Howard Bregman, Abdurrahman Keskin, Andrea Santeford, Rajendra S. Apte, Raghav Sehgal, Britney Johnson, Gaya K. Amarasinghe, Miguel P. Soares, Takashi Satoh, Shizuo Akira, Tsonwin Hai, Cristina Guzman Strong, Karine Auclair, Thomas P. Roddy, Scott A. Biller, Marko Jovanovic, Eynav Klechevsky, Kelly M. Stewart, Gwendalyn J. Randolph and Maxim N. Artyomov

Genetic identification of leptin neural circuits in energy and glucose homeostases pp. 505-509

Jie Xu, Christopher L. Bartolome, Cho Shing Low, Xinchi Yi, Cheng-Hao Chien, Peng Wang and Dong Kong

Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells pp. 510-514

Hong Sook Kim, Yuliang Tan, Wubin Ma, Daria Merkurjev, Eugin Destici, Qi Ma, Tom Suter, Kenneth Ohgi, Meyer Friedman, Dorota Skowronska-Krawczyk and Michael G. Rosenfeld

Mechanism of NMDA receptor channel block by MK-801 and memantine pp. 515-519

Xianqiang Song, Morten Ø. Jensen, Vishwanath Jogini, Richard A. Stein, Chia-Hsueh Lee, Hassane S. Mchaourab, David E. Shaw and Eric Gouaux

Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor pp. 520-524

Zhenlin Yang, Shuo Han, Max Keller, Anette Kaiser, Brian J. Bender, Mathias Bosse, Kerstin Burkert, Lisa M. Kögler, David Wifling, Guenther Bernhardt, Nicole Plank, Timo Littmann, Peter Schmidt, Cuiying Yi, Beibei Li, Sheng Ye, Rongguang Zhang, Bo Xu, Dan Larhammar, Raymond C. Stevens, Daniel Huster, Jens Meiler, Qiang Zhao, Annette G. Beck-Sickinger, Armin Buschauer and Beili Wu

A photo celebration of scientists at work pp. 525-527

Jack Leeming

My favourite sentience pp. 530-530

Marissa Lingen

2018, volume 556, articles 7701

Science must rise up to support people like me pp. 275-275

Aaron Schaal

Great Barrier Reef saw huge losses from 2016 heatwave pp. 281-282

Quirin Schiermeier

East Asia braces for surge in deadly tick-borne virus pp. 282-283

David Cyranoski

US environmental group wins millions to develop methane-monitoring satellite pp. 283-283

Jeff Tollefson

Air-pollution trackers seek to fill Africa’s data gap pp. 284-284

Nicole Wetsman

Spain’s biggest-ever science petition decries ‘abandonment’ of research pp. 285-285

Michele Catanzaro

Attacks in UK and Syria highlight growing need for chemical-forensics expertise pp. 285-286

Declan Butler

How to blow up a star pp. 287-289

Elizabeth Gibney

Medicine’s secret ingredient — it’s in the timing pp. 290-292

Lynne Peeples

How to curb production of chemical weapons pp. 293-295

Leiv K. Sydnes

Regulate artificial intelligence to avert cyber arms race pp. 296-298

Mariarosaria Taddeo and Luciano Floridi

How to retool our concept of value pp. 300-301

Robert Costanza

The trouble with the Nobel prize pp. 301-302

Ron Cowen

Talking sense on climate change, the biology of behaviour and a prehistoric shark with a twist: New in paperback pp. 302-308

Mary Craig

When feathers flew at a natural-history archive pp. 303-304

Stuart Pimm

The illusion of time pp. 304-305

Andrew Jaffe

War and peace and summer camp pp. 306-307

Alex Haslam

The long search for the pain gene pp. 308-308

Tor Wager

Long-term tracking of biodiversity is more important than ever pp. 309-309

Lisa Norton

Code reviewing puts extra demands on referees pp. 309-309

Nicolas P. Rougier and Konrad Hinsen

A repository for quality-assured data on enzyme activity pp. 309-309

Neil Swainston and Carsten Kettner

Sharp rise in premier papers from Brazilian universities pp. 309-309

Gabriel José de Carli and Tiago Campos Pereira

Steer cancer funding to align with clinical goals pp. 309-309

Johnathan Watkins and Wahyu Wulaningsih

Immune memory in the brain pp. 312-313

Alexi Nott and Christopher K. Glass

Peptides used to make light-twisting nanoparticles pp. 313-314

Guillermo González-Rubio and Luis M. Liz-Marzán

When sex differences lead to extinction pp. 315-316

Hanna Kokko

Electronics and photonics united pp. 316-318

Goran Z. Mashanovich

A stockpile of antiviral defences pp. 318-319

Sébastien Levesque and Sylvain Moineau

Bounteous black holes at the Galactic Centre pp. 319-320

Mark R. Morris

Laser spectroscopic characterization of the nuclear-clock isomer 229mTh pp. 321-325

Johannes Thielking, Maxim V. Okhapkin, Przemysław Głowacki, David M. Meier, Lars Wense, Benedict Seiferle, Christoph E. Düllmann, Peter G. Thirolf and Ekkehard Peik

Functional circuit architecture underlying parental behaviour pp. 326-331

Johannes Kohl, Benedicte M. Babayan, Nimrod D. Rubinstein, Anita E. Autry, Brenda Marin-Rodriguez, Vikrant Kapoor, Kazunari Miyamishi, Larry S. Zweifel, Liqun Luo, Naoshige Uchida and Catherine Dulac

Innate immune memory in the brain shapes neurological disease hallmarks pp. 332-338

Ann-Christin Wendeln, Karoline Degenhardt, Lalit Kaurani, Michael Gertig, Thomas Ulas, Gaurav Jain, Jessica Wagner, Lisa M. Häsler, Katleen Wild, Angelos Skodras, Thomas Blank, Ori Staszewski, Moumita Datta, Tonatiuh Pena Centeno, Vincenzo Capece, Md. Rezaul Islam, Cemil Kerimoglu, Matthias Staufenbiel, Joachim L. Schultze, Marc Beyer, Marco Prinz, Mathias Jucker, André Fischer and Jonas J. Neher

Genome evolution across 1,011 Saccharomyces cerevisiae isolates pp. 339-344

Jackson Peter, Matteo De Chiara, Anne Friedrich, Jia-Xing Yue, David Pflieger, Anders Bergström, Anastasie Sigwalt, Benjamin Barre, Kelle Freel, Agnès Llored, Corinne Cruaud, Karine Labadie, Jean-Marc Aury, Benjamin Istace, Kevin Lebrigand, Pascal Barbry, Stefan Engelen, Arnaud Lemainque, Patrick Wincker, Gianni Liti and Joseph Schacherer

Two separate outflows in the dual supermassive black hole system NGC 6240 pp. 345-348

F. Müller-Sánchez, R. Nevin, J. M. Comerford, R. I. Davies, G. C. Privon and E. Treister

Integrating photonics with silicon nanoelectronics for the next generation of systems on a chip pp. 349-354

Amir H. Atabaki, Sajjad Moazeni, Fabio Pavanello, Hayk Gevorgyan, Jelena Notaros, Luca Alloatti, Mark T. Wade, Chen Sun, Seth A. Kruger, Huaiyu Meng, Kenaish Al Qubaisi, Imbert Wang, Bohan Zhang, Anatol Khilo, Christopher V. Baiocco, Miloš A. Popović, Vladimir M. Stojanović and Rajeev J. Ram

A library of atomically thin metal chalcogenides pp. 355-359

Jiadong Zhou, Junhao Lin, Xiangwei Huang, Yao Zhou, Yu Chen, Juan Xia, Hong Wang, Yu Xie, Huimei Yu, Jincheng Lei, Di Wu, Fucai Liu, Qundong Fu, Qingsheng Zeng, Chuang-Han Hsu, Changli Yang, Li Lu, Ting Yu, Zexiang Shen, Hsin Lin, Boris I. Yakobson, Qian Liu, Kazu Suenaga, Guangtong Liu and Zheng Liu

Amino-acid- and peptide-directed synthesis of chiral plasmonic gold nanoparticles pp. 360-365

Hye-Eun Lee, Hyo-Yong Ahn, Jungho Mun, Yoon Young Lee, Minkyung Kim, Nam Heon Cho, Kiseok Chang, Wook Sung Kim, Junsuk Rho and Ki Tae Nam

High male sexual investment as a driver of extinction in fossil ostracods pp. 366-369

Maria João Fernandes Martins, T. Markham Puckett, Rowan Lockwood, John P. Swaddle and Gene Hunt

Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size pp. 370-375

Matthew B. Johnson, Xingshen Sun, Andrew Kodani, Rebeca Borges-Monroy, Kelly M. Girskis, Steven C. Ryu, Peter P. Wang, Komal Patel, Dilenny M. Gonzalez, Yu Mi Woo, Ziying Yan, Bo Liang, Richard S. Smith, Manavi Chatterjee, Daniel Coman, Xenophon Papademetris, Lawrence H. Staib, Fahmeed Hyder, Joseph B. Mandeville, P. Ellen Grant, Kiho Im, Hojoong Kwak, John F. Engelhardt, Christopher A. Walsh and Byoung-Il Bae

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis pp. 376-380

Kifayathullah Liakath-Ali, Eric W. Mills, Inês Sequeira, Beate M. Lichtenberger, Angela Oliveira Pisco, Kalle H. Sipilä, Ajay Mishra, Harunori Yoshikawa, Colin Chih-Chien Wu, Tony Ly, Angus I. Lamond, Ibrahim M. Adham, Rachel Green and Fiona M. Watt

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity pp. 381-385

Kuan-Chuan Pao, Nicola T. Wood, Axel Knebel, Karim Rafie, Mathew Stanley, Peter D. Mabbitt, Ramasubramanian Sundaramoorthy, Kay Hofmann, Daan M. F. Aalten and Satpal Virdee

Structural basis for ATP-dependent chromatin remodelling by the INO80 complex pp. 386-390

Sebastian Eustermann, Kevin Schall, Dirk Kostrewa, Kristina Lakomek, Mike Strauss, Manuela Moldt and Karl-Peter Hopfner

Structure and regulation of the human INO80–nucleosome complex pp. 391-395

Rafael Ayala, Oliver Willhoft, Ricardo J. Aramayo, Martin Wilkinson, Elizabeth A. McCormack, Lorraine Ocloo, Dale B. Wigley and Xiaodong Zhang

YouTube your science pp. 397-398

Adrian A. Smith

Space pioneer pp. 399-399

Virginia Gewin

Wasteland of sand and ice pp. 402-402

Tomás McMahon

2018, volume 556, articles 7700

Collaboration is the key to cancer research pp. S1-S3

Neil Savage

Demand cancer drugs that truly help patients pp. 151-151

Ajay Aggarwal

Beijing launches pioneering brain-science centre pp. 157-158

David Cyranoski

NASA’s next exoplanet hunter will seek worlds close to home pp. 158-159

Alexandra Witze

Science’s vast gender pay gap revealed in UK wage data pp. 160-160

Holly Else

Cutting-edge cancer drug hobbled by diagnostic test confusion pp. 161-162

Heidi Ledford

Plan to dismantle Puerto Rico’s statistics agency gets green light pp. 161-161

Giorgia Guglielmi

How gravitational waves could solve some of the Universe’s deepest mysteries pp. 164-168

Davide Castelvecchi

People must retain control of autonomous vehicles pp. 169-171

Ashley Nunes, Bryan Reimer and Joseph F. Coughlin

A physicist probes the metaphysical pp. 172-173

Anil Ananthaswamy

The deep past of megafires, big data’s Achilles heel and behind the scenes of the March for Science: Books in brief pp. 173-173

Barbara Kiser

Take a holistic view when making pesticide policies stricter pp. 174-174

Robert Finger

Build two-way rapport for better policymaking pp. 174-174

Adam P. Hejnowicz, Sue E. Hartley and Nigel Gilbert

Curtail climate-change effects using Singapore Index of Cities’ Biodiversity pp. 174-174

Sameen Ahmed Khan

Don’t dismiss citations to journals not published in English pp. 174-174

Vladimir S. Lazarev and Serhii A. Nazarovets

Save a North Sea fish from becoming museum piece pp. 174-174

Jon C. Svendsen, Aage K. O. Alstrup and Lasse F. Jensen

The certainty of quantum randomness pp. 176-177

Stefano Pironio

Mirrors made of a single atomic layer pp. 177-178

Kin Fai Mak and Jie Shan

Peptide signal alerts plants to drought pp. 178-179

Alexander Christmann and Erwin Grill

North Atlantic circulation slows down pp. 180-181

Summer K. Praetorius

The telomerase enzyme and liver renewal pp. 181-182

Kenneth S. Zaret

Backbone of RNA viruses uncovered pp. 182-183

Mark Zeller and Kristian G. Andersen

Reversible Mn2+/Mn4+ double redox in lithium-excess cathode materials pp. 185-190

Jinhyuk Lee, Daniil A. Kitchaev, Deok-Hwang Kwon, Chang-Wook Lee, Joseph K. Papp, Yi-Sheng Liu, Zhengyan Lun, Raphaële J. Clément, Tan Shi, Bryan D. McCloskey, Jinghua Guo, Mahalingam Balasubramanian and Gerbrand Ceder

Observed fingerprint of a weakening Atlantic Ocean overturning circulation pp. 191-196

L. Caesar, S. Rahmstorf, A. Robinson, G. Feulner and V. Saba

The evolutionary history of vertebrate RNA viruses pp. 197-202

Mang Shi, Xian-Dan Lin, Xiao Chen, Jun-Hua Tian, Liang-Jun Chen, Kun Li, Wen Wang, John-Sebastian Eden, Jin-Jin Shen, Li Liu, Edward C. Holmes and Yong-Zhen Zhang

Cryo-EM structure of the Blastochloris viridis LH1–RC complex at 2.9 Å pp. 203-208

Pu Qian, C. Alistair Siebert, Peiyi Wang, Daniel P. Canniffe and C. Neil Hunter

Structure of photosynthetic LH1–RC supercomplex at 1.9 Å resolution pp. 209-213

Long-Jiang Yu, Michihiro Suga, Zheng-Yu Wang-Otomo and Jian-Ren Shen

Crystal structures of the gastric proton pump pp. 214-218

Kazuhiro Abe, Katsumasa Irie, Hanayo Nakanishi, Hiroshi Suzuki and Yoshinori Fujiyoshi

Alteration of the magnetosphere of the Vela pulsar during a glitch pp. 219-222

Jim Palfreyman, John M. Dickey, Aidan Hotan, Simon Ellingsen and Willem Straten

Experimentally generated randomness certified by the impossibility of superluminal signals pp. 223-226

Peter Bierhorst, Emanuel Knill, Scott Glancy, Yanbao Zhang, Alan Mink, Stephen Jordan, Andrea Rommal, Yi-Kai Liu, Bradley Christensen, Sae Woo Nam, Martin J. Stevens and Lynden K. Shalm

Anomalously weak Labrador Sea convection and Atlantic overturning during the past 150 years pp. 227-230

David J. R. Thornalley, Delia W. Oppo, Pablo Ortega, Jon I. Robson, Chris M. Brierley, Renee Davis, Ian R. Hall, Paola Moffa-Sanchez, Neil L. Rose, Peter T. Spooner, Igor Yashayaev and Lloyd D. Keigwin

Accelerated increase in plant species richness on mountain summits is linked to warming pp. 231-234

Manuel J. Steinbauer, John-Arvid Grytnes, Gerald Jurasinski, Aino Kulonen, Jonathan Lenoir, Harald Pauli, Christian Rixen, Manuela Winkler, Manfred Bardy-Durchhalter, Elena Barni, Anne D. Bjorkman, Frank T. Breiner, Sarah Burg, Patryk Czortek, Melissa A. Dawes, Anna Delimat, Stefan Dullinger, Brigitta Erschbamer, Vivian A. Felde, Olatz Fernández-Arberas, Kjetil F. Fossheim, Daniel Gómez-García, Damien Georges, Erlend T. Grindrud, Sylvia Haider, Siri V. Haugum, Hanne Henriksen, María J. Herreros, Bogdan Jaroszewicz, Francesca Jaroszynska, Robert Kanka, Jutta Kapfer, Kari Klanderud, Ingolf Kühn, Andrea Lamprecht, Magali Matteodo, Umberto Morra Cella, Signe Normand, Arvid Odland, Siri L. Olsen, Sara Palacio, Martina Petey, Veronika Piscová, Blazena Sedlakova, Klaus Steinbauer, Veronika Stöckli, Jens-Christian Svenning, Guido Teppa, Jean-Paul Theurillat, Pascal Vittoz, Sarah J. Woodin, Niklaus E. Zimmermann and Sonja Wipf

A small peptide modulates stomatal control via abscisic acid in long-distance signalling pp. 235-238

Fuminori Takahashi, Takehiro Suzuki, Yuriko Osakabe, Shigeyuki Betsuyaku, Yuki Kondo, Naoshi Dohmae, Hiroo Fukuda, Kazuko Yamaguchi-Shinozaki and Kazuo Shinozaki

Advanced maturation of human cardiac tissue grown from pluripotent stem cells pp. 239-243

Kacey Ronaldson-Bouchard, Stephen P. Ma, Keith Yeager, Timothy Chen, LouJin Song, Dario Sirabella, Kumi Morikawa, Diogo Teles, Masayuki Yazawa and Gordana Vunjak-Novakovic

Distributed hepatocytes expressing telomerase repopulate the liver in homeostasis and injury pp. 244-248

Shengda Lin, Elisabete M. Nascimento, Chandresh R. Gajera, Lu Chen, Patrick Neuhöfer, Alina Garbuzov, Sui Wang and Steven E. Artandi

Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer pp. 249-254

Subhamoy Dasgupta, Kimal Rajapakshe, Bokai Zhu, Bryan C. Nikolai, Ping Yi, Nagireddy Putluri, Jong Min Choi, Sung Y. Jung, Cristian Coarfa, Thomas F. Westbrook, Xiang H.-F. Zhang, Charles E. Foulds, Sophia Y. Tsai, Ming-Jer Tsai and Bert W. O’Malley

Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin pp. 255-258

Peng Zhou, Hang Fan, Tian Lan, Xing-Lou Yang, Wei-Feng Shi, Wei Zhang, Yan Zhu, Ya-Wei Zhang, Qing-Mei Xie, Shailendra Mani, Xiao-Shuang Zheng, Bei Li, Jin-Man Li, Hua Guo, Guang-Qian Pei, Xiao-Ping An, Jun-Wei Chen, Ling Zhou, Kai-Jie Mai, Zi-Xian Wu, Di Li, Danielle E. Anderson, Li-Biao Zhang, Shi-Yue Li, Zhi-Qiang Mi, Tong-Tong He, Feng Cong, Peng-Ju Guo, Ren Huang, Yun Luo, Xiang-Ling Liu, Jing Chen, Yong Huang, Qiang Sun, Xiang-Li-Lan Zhang, Yuan-Yuan Wang, Shao-Zhen Xing, Yan-Shan Chen, Yuan Sun, Juan Li, Peter Daszak, Lin-Fa Wang, Zheng-Li Shi, Yi-Gang Tong and Jing-Yun Ma

Cancer research with a human touch pp. 259-261

Mike May

Outsourcing is in pp. 263-265

Esther Landhuis

Convert your weaknesses into assets pp. 265-265

Lia Paola Zambetti

e-PLURIBUS pp. 268-268

S. R. Algernon

2018, volume 556, articles 7699

Improving outcomes in congenital cataract pp. E1-E2

Ameenat Lola Solebo, Christopher J. Hammond and Jugnoo S. Rahi

Lens regeneration in children pp. E2-E3

Demetrios G. Vavvas, Thaddeus P. Dryja, M. Edward Wilson, Timothy W. Olsen, Ankoor Shah, Ula Jurkunas, Roberto Pineda, Vasiliki Poulaki, Sotiria Palioura, Peter Veldman, Javier Moreno-Montañés, Maria D. Pinazo-Duran, José Carlos Pastor, Miltiadis Tsilimbaris, Douglas Rhee, Kathryn Colby, David G. Hunter, Solon Thanos, Taiji Sakamoto, Louis R. Pasquale, Joan W. Miller, Deborah VanderVeen and Scott R. Lambert

Liu et al. reply pp. E3-E4

Yizhi Liu, David Granet, Haotian Lin, Sally Baxter, Hong Ouyang, Jie Zhu, Shan Huang, Zhenzhen Liu, Xiaokang Wu, Fangbing Yan, Xialin Liu, Lixia Luo, Christopher Heichel, Meixia Zhang, Wenjia Cai, Richard L. Maas and Kang Zhang

Investigating non-Joulian magnetostriction pp. E5-E7

Yangkun He, Yongjun Han, P. Stamenov, B. Kundys, J. M. D. Coey, Chengbao Jiang and Huibin Xu

Use our personal data for the common good pp. 7-7

Hetan Shah

NASA reveals major delay for $8-billion Hubble successor pp. 11-12

Alexandra Witze

Cancer researchers push to relax rules for clinical trials pp. 12-13

Heidi Ledford

Beguiling dark-matter signal persists 20 years on pp. 13-14

Davide Castelvecchi

EU copyright reforms draw fire from scientists pp. 14-15

Quirin Schiermeier

Squeaky clean mice could be ruining research pp. 16-18

Cassandra Willyard

Reward food companies for improving nutrition pp. 19-22

Lawrence Haddad

Developing countries must lead on solar geoengineering research pp. 22-24

A. Atiq Rahman, Paulo Artaxo, Asfawossen Asrat and Andy Parker

Swansong of Hans Rosling, data visionary pp. 25-26

Jim O’Neill

From meat to mind: the root of consciousness pp. 26-27

Douwe Draaisma

Tom Lehrer at 90: a life of scientific satire pp. 27-28

Andrew Robinson

Uphold Hawking’s and Sulston’s support for European science pp. 31-31

Rolf Heuer and Paul Nurse

Alfred Nobel’s 1895 will is strictly upheld to this day pp. 31-31

Göran K. Hansson

How philosophy was squeezed out of the PhD pp. 31-31

Michael Stocker

Sciences unite in Spain to promote research for advancing society pp. 31-31

Fernando Baquero and Jose A. Gutiérrez-Fuentes

Uptick in US female members of International Astronomical Union pp. 31-31

David Soderblom

Günter Blobel (1936–2018) pp. 32-32

Sanford Simon

Mississippi rising pp. 34-35

Scott St. George

Forests in flux as climate varies pp. 35-37

Sebastiaan Luyssaert and J. Hans C. Cornelissen

Novel electronic states seen in graphene pp. 37-38

Eugene J. Mele

Two-pore channels open up pp. 38-40

Sandip Patel

Bacterial persister cells tackled pp. 40-41

Julian G. Hurdle and Aditi Deshpande

Observations of the birth of crystals pp. 41-42

Robert G. Alberstein and F. Akif Tezcan

Unconventional superconductivity in magic-angle graphene superlattices pp. 43-50

Yuan Cao, Valla Fatemi, Shiang Fang, Kenji Watanabe, Takashi Taniguchi, Efthimios Kaxiras and Pablo Jarillo-Herrero

The logic of single-cell projections from visual cortex pp. 51-56

Yunyun Han, Justus M. Kebschull, Robert A. A. Campbell, Devon Cowan, Fabia Imhof, Anthony M. Zador and Thomas D. Mrsic-Flogel

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity pp. 57-63

Johnny H. Hu, Shannon M. Miller, Maarten H. Geurts, Weixin Tang, Liwei Chen, Ning Sun, Christina M. Zeina, Xue Gao, Holly A. Rees, Zhi Lin and David R. Liu

Architecture of the human GATOR1 and GATOR1–Rag GTPases complexes pp. 64-69

Kuang Shen, Rick K. Huang, Edward J. Brignole, Kendall J. Condon, Max L. Valenstein, Lynne Chantranupong, Aimaiti Bomaliyamu, Abigail Choe, Chuan Hong, Zhiheng Yu and David M. Sabatini

A density cusp of quiescent X-ray binaries in the central parsec of the Galaxy pp. 70-73

Charles J. Hailey, Kaya Mori, Franz E. Bauer, Michael E. Berkowitz, Jaesub Hong and Benjamin J. Hord

RETRACTED ARTICLE: Quantized Majorana conductance pp. 74-79

Hao Zhang, Chun-Xiao Liu, Sasa Gazibegovic, Di Xu, John A. Logan, Guanzhong Wang, Nick van Loo, Jouri D. S. Bommer, Michiel W. A. de Moor, Diana Car, Roy L. M. Op het Veld, Petrus J. van Veldhoven, Sebastian Koelling, Marcel A. Verheijen, Mihir Pendharkar, Daniel J. Pennachio, Borzoyeh Shojaei, Joon Sue Lee, Chris J. Palmstrøm, Erik P. A. M. Bakkers, S. Das Sarma and Leo P. Kouwenhoven

Correlated insulator behaviour at half-filling in magic-angle graphene superlattices pp. 80-84

Yuan Cao, Valla Fatemi, Ahmet Demir, Shiang Fang, Spencer L. Tomarken, Jason Y. Luo, Javier D. Sanchez-Yamagishi, Kenji Watanabe, Takashi Taniguchi, Efthimios Kaxiras, Ray C. Ashoori and Pablo Jarillo-Herrero

Room-temperature nine-µm-wavelength photodetectors and GHz-frequency heterodyne receivers pp. 85-88

Daniele Palaferri, Yanko Todorov, Azzurra Bigioli, Alireza Mottaghizadeh, Djamal Gacemi, Allegra Calabrese, Angela Vasanelli, Lianhe Li, A. Giles Davies, Edmund H. Linfield, Filippos Kapsalidis, Mattias Beck, Jérôme Faist and Carlo Sirtori

Molecular nucleation mechanisms and control strategies for crystal polymorph selection pp. 89-94

Alexander E. S. Van Driessche, Nani Van Gerven, Paul H. H. Bomans, Rick R. M. Joosten, Heiner Friedrich, David Gil-Carton, Nico A. J. M. Sommerdijk and Mike Sleutel

Climatic control of Mississippi River flood hazard amplified by river engineering pp. 95-98

Samuel E. Munoz, Liviu Giosan, Matthew D. Therrell, Jonathan W. F. Remo, Zhixiong Shen, Richard M. Sullivan, Charlotte Wiman, Michelle O’Donnell and Jeffrey P. Donnelly

Shifts in tree functional composition amplify the response of forest biomass to climate pp. 99-102

Tao Zhang, Ülo Niinemets, Justin Sheffield and Jeremy W. Lichstein

A new class of synthetic retinoid antibiotics effective against bacterial persisters pp. 103-107

Wooseong Kim, Wenpeng Zhu, Gabriel Lambert Hendricks, Daria Van Tyne, Andrew D. Steele, Colleen E. Keohane, Nico Fricke, Annie L. Conery, Steven Shen, Wen Pan, Kiho Lee, Rajmohan Rajamuthiah, Beth Burgwyn Fuchs, Petia M. Vlahovska, William M. Wuest, Michael S. Gilmore, Huajian Gao, Frederick M. Ausubel and Eleftherios Mylonakis

Whole-organism clone tracing using single-cell sequencing pp. 108-112

Anna Alemany, Maria Florescu, Chloé S. Baron, Josi Peterson-Maduro and Alexander van Oudenaarden

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 pp. 113-117

Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P. Jedrychowski, Ana S. H. Costa, Maureen Higgins, Emily Hams, John Szpyt, Marah C. Runtsch, Martin S. King, Joanna F. McGouran, Roman Fischer, Benedikt M. Kessler, Anne F. McGettrick, Mark M. Hughes, Richard G. Carroll, Lee M. Booty, Elena V. Knatko, Paul J. Meakin, Michael L. J. Ashford, Louise K. Modis, Gino Brunori, Daniel C. Sévin, Padraic G. Fallon, Stuart T. Caldwell, Edmund R. S. Kunji, Edward T. Chouchani, Christian Frezza, Albena T. Dinkova-Kostova, Richard C. Hartley, Michael P. Murphy and Luke A. O’Neill

Structure of the peptidoglycan polymerase RodA resolved by evolutionary coupling analysis pp. 118-121

Megan Sjodt, Kelly Brock, Genevieve Dobihal, Patricia D. A. Rohs, Anna G. Green, Thomas A. Hopf, Alexander J. Meeske, Veerasak Srisuknimit, Daniel Kahne, Suzanne Walker, Debora S. Marks, Thomas G. Bernhardt, David Z. Rudner and Andrew C. Kruse

Structure of the insulin receptor–insulin complex by single-particle cryo-EM analysis pp. 122-125

Giovanna Scapin, Venkata P. Dandey, Zhening Zhang, Winifred Prosise, Alan Hruza, Theresa Kelly, Todd Mayhood, Corey Strickland, Clinton S. Potter and Bridget Carragher

Modular assembly of the nucleolar pre-60S ribosomal subunit pp. 126-129

Zahra Assur Sanghai, Linamarie Miller, Kelly R. Molloy, Jonas Barandun, Mirjam Hunziker, Malik Chaker-Margot, Junjie Wang, Brian T. Chait and Sebastian Klinge

Structural insights into the voltage and phospholipid activation of the mammalian TPC1 channel pp. 130-134

Ji She, Jiangtao Guo, Qingfeng Chen, Weizhong Zeng, Youxing Jiang and Xiao-chen Bai

Correction: Corrigendum: Commensal bacteria make GPCR ligands that mimic human signalling molecules pp. 135-135

Louis J. Cohen, Daria Esterhazy, Seong-Hwan Kim, Christophe Lemetre, Rhiannon R. Aguilar, Emma A. Gordon, Amanda J. Pickard, Justin R. Cross, Ana B. Emiliano, Sun M. Han, John Chu, Xavier Vila-Farres, Jeremy Kaplitt, Aneta Rogoz, Paula Y. Calle, Craig Hunter, J. Kipchirchir Bitok and Sean F. Brady

Erratum: Asparagine bioavailability governs metastasis in a model of breast cancer pp. 135-135

Simon R. V. Knott, Elvin Wagenblast, Showkhin Khan, Sun Y. Kim, Mar Soto, Michel Wagner, Marc-Olivier Turgeon, Lisa Fish, Nicolas Erard, Annika L. Gable, Ashley R. Maceli, Steffen Dickopf, Evangelia K. Papachristou, Clive S. D’Santos, Lisa A. Carey, John E. Wilkinson, J. Chuck Harrell, Charles M. Perou, Hani Goodarzi, George Poulogiannis and Gregory J. Hannon

Erratum: Evolutionary history resolves global organization of root functional traits pp. 135-135

Zeqing Ma, Dali Guo, Xingliang Xu, Mingzhen Lu, Richard D. Bardgett, David M. Eissenstat, M. Luke McCormack and Lars O. Hedin

Ecology’s remote-sensing revolution pp. 137-138

Roberta Kwok

How researchers are ensuring that their work has an impact pp. 139-141

Jack Leeming

Requiem pp. 144-144

Christine Lucas