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2016, volume 532, articles 7600

Saudi Arabia pp. S1-S1

Mohammed Yahia

Sights set on a central role pp. S2-S3

Larissa Kogleck

A 21st century transformation pp. S4-S9

Sedeer El-Showk

Making the most of financial might pp. S10-S12

Pakinam Amer

Oiling the wheels on a road to success pp. S13-S15

Pakinam Amer

Shared knowledge is key to a kingdom pp. S16-S18

Nadia El-Awady

Making the most of local expertise pp. S19-S21

Nadia El-Awady

Speak up about subtle sexism in science pp. 415-415

Tricia Serio

Devastating wheat fungus appears in Asia for first time pp. 421-422

Ewen Callaway

AI talent grab sparks excitement and concern pp. 422-423

Elizabeth Gibney

Scientists worry as cancer moonshots multiply pp. 424-425

Erika Check Hayden

Researchers push for personalized tumour vaccines pp. 425-425

Heidi Ledford

Europe plans giant billion-euro quantum technologies project pp. 426-426

Elizabeth Gibney

AstraZeneca launches project to sequence 2 million genomes pp. 427-427

Heidi Ledford

Killer landslides: The lasting legacy of Nepal’s quake pp. 428-431

Jane Qiu

The quiet revolutionary: How the co-discovery of CRISPR explosively changed Emmanuelle Charpentier’s life pp. 432-434

Alison Abbott

Seven chemical separations to change the world pp. 435-437

David S. Sholl and Ryan P. Lively

Technology: Beyond the 'InterNyet' pp. 438-439

Michael D. Gordin

Books in brief pp. 439-439

Barbara Kiser

Zoology: In the museum with Roosevelt pp. 440-440

Michael Ross Canfield

Benefits of trade in amber fossils pp. 441-441

Jun Chen, Bo Wang and Edmund A. Jarzembowski

Postdoc rights need not hurt productivity pp. 441-441

Nuno Cerca

Ventilating Beijing cannot fix pollution pp. 441-441

Yansui Liu, Yang Zhou and Yurui Li

Anti-science wave sweeps Poland pp. 441-441

Paula Dobosz and Jakub Zawiła-Niedźwiecki

Tell us the end of the story pp. 441-441

M. Usman, A. Chaudhary and M. Farooq

R. McNeill Alexander (1934–2016) pp. 442-442

Andrew A. Biewener and Alan Wilson

The rise of Rhizaria pp. 444-445

David A. Caron

Cracks help membranes to stay hydrated pp. 445-446

Jovan Kamcev and Benny D. Freeman

Getting the measure of a monster pp. 447-448

Shigeru Kuratani and Tatsuya Hirasawa

Fault tolerance in the brain pp. 449-450

Byron M. Yu

Four neutrons together momentarily pp. 449-449

Carlos A. Bertulani and Vladimir Zelevinsky

Glitches in time pp. 450-451

Charlotte A. L. Haley

Natural speech reveals the semantic maps that tile human cerebral cortex pp. 453-458

Alexander G. Huth, Wendy A. de Heer, Thomas L. Griffiths, Frédéric E. Theunissen and Jack L. Gallant

Robust neuronal dynamics in premotor cortex during motor planning pp. 459-464

Nuo Li, Kayvon Daie, Karel Svoboda and Shaul Druckmann

Plankton networks driving carbon export in the oligotrophic ocean pp. 465-470

Lionel Guidi, Samuel Chaffron, Lucie Bittner, Damien Eveillard, Abdelhalim Larhlimi, Simon Roux, Youssef Darzi, Stephane Audic, Léo Berline, Jennifer R. Brum, Luis Pedro Coelho, Julio Cesar Ignacio Espinoza, Shruti Malviya, Shinichi Sunagawa, Céline Dimier, Stefanie Kandels-Lewis, Marc Picheral, Julie Poulain, Sarah Searson, Lars Stemmann, Fabrice Not, Pascal Hingamp, Sabrina Speich, Mick Follows, Lee Karp-Boss, Emmanuel Boss, Hiroyuki Ogata, Stephane Pesant, Jean Weissenbach, Patrick Wincker, Silvia G. Acinas, Peer Bork, Colomban de Vargas, Daniele Iudicone, Matthew B. Sullivan, Jeroen Raes, Eric Karsenti, Chris Bowler and Gabriel Gorsky

Dynamics from noisy data with extreme timing uncertainty pp. 471-475

R. Fung, A. M. Hanna, O. Vendrell, S. Ramakrishna, T. Seideman, R. Santra and A. Ourmazd

Quantum phases from competing short- and long-range interactions in an optical lattice pp. 476-479

Renate Landig, Lorenz Hruby, Nishant Dogra, Manuele Landini, Rafael Mottl, Tobias Donner and Tilman Esslinger

Nanocrack-regulated self-humidifying membranes pp. 480-483

Chi Hoon Park, So Young Lee, Doo Sung Hwang, Dong Won Shin, Doo Hee Cho, Kang Hyuck Lee, Tae-Woo Kim, Tae-Wuk Kim, Mokwon Lee, Deok-Soo Kim, Cara M. Doherty, Aaron W. Thornton, Anita J. Hill, Michael D. Guiver and Young Moo Lee

The pentadehydro-Diels–Alder reaction pp. 484-488

Teng Wang, Rajasekhar Reddy Naredla, Severin K. Thompson and Thomas R. Hoye

Rapid cycling of reactive nitrogen in the marine boundary layer pp. 489-491

Chunxiang Ye, Xianliang Zhou, Dennis Pu, Jochen Stutz, James Festa, Max Spolaor, Catalina Tsai, Christopher Cantrell, Roy L. Mauldin, Teresa Campos, Andrew Weinheimer, Rebecca S. Hornbrook, Eric C. Apel, Alex Guenther, Lisa Kaser, Bin Yuan, Thomas Karl, Julie Haggerty, Samuel Hall, Kirk Ullmann, James N. Smith, John Ortega and Christoph Knote

Bubble accumulation and its role in the evolution of magma reservoirs in the upper crust pp. 492-495

A. Parmigiani, S. Faroughi, C. Huber, O. Bachmann and Y. Su

The ‘Tully monster’ is a vertebrate pp. 496-499

Victoria E. McCoy, Erin E. Saupe, James C. Lamsdell, Lidya G. Tarhan, Sean McMahon, Scott Lidgard, Paul Mayer, Christopher D. Whalen, Carmen Soriano, Lydia Finney, Stefan Vogt, Elizabeth G. Clark, Ross P. Anderson, Holger Petermann, Emma R. Locatelli and Derek E. G. Briggs

The eyes of Tullimonstrum reveal a vertebrate affinity pp. 500-503

Thomas Clements, Andrei Dolocan, Peter Martin, Mark A. Purnell, Jakob Vinther and Sarah E. Gabbott

In situ imaging reveals the biomass of giant protists in the global ocean pp. 504-507

Tristan Biard, Lars Stemmann, Marc Picheral, Nicolas Mayot, Pieter Vandromme, Helena Hauss, Gabriel Gorsky, Lionel Guidi, Rainer Kiko and Fabrice Not

Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells pp. 508-511

Stefan Rentas, Nicholas T. Holzapfel, Muluken S. Belew, Gabriel A. Pratt, Veronique Voisin, Brian T. Wilhelm, Gary D. Bader, Gene W. Yeo and Kristin J. Hope

Normalizing the environment recapitulates adult human immune traits in laboratory mice pp. 512-516

Lalit K. Beura, Sara E. Hamilton, Kevin Bi, Jason M. Schenkel, Oludare A. Odumade, Kerry A. Casey, Emily A. Thompson, Kathryn A. Fraser, Pamela C. Rosato, Ali Filali-Mouhim, Rafick P. Sekaly, Marc K. Jenkins, Vaiva Vezys, W. Nicholas Haining, Stephen C. Jameson and David Masopust

The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA pp. 517-521

Ines Fonfara, Hagen Richter, Majda Bratovič, Anaïs Le Rhun and Emmanuelle Charpentier

The crystal structure of Cpf1 in complex with CRISPR RNA pp. 522-526

Dong De, Kuan Ren, Xiaolin Qiu, Jianlin Zheng, Minghui Guo, Xiaoyu Guan, Hongnan Liu, Ningning Li, Bailing Zhang, Daijun Yang, Chuang Ma, Shuo Wang, Dan Wu, Yunfeng Ma, Shilong Fan, Jiawei Wang, Ning Gao and Zhiwei Huang

Crystal structure of the human σ1 receptor pp. 527-530

Hayden R. Schmidt, Sanduo Zheng, Esin Gurpinar, Antoine Koehl, Aashish Manglik and Andrew C. Kruse

Non-profit work: Take my advice pp. 531-533

Chris Woolston

Turning point: Carpe freedom pp. 533-533

Virginia Gewin

A slice of time pp. 536-536

Jeff Hecht

2016, volume 532, articles 7599

The Paris Agreement has solved a troubling problem pp. 283-283

Simon L. Lewis

Gene-editing research in human embryos gains momentum pp. 289-290

Ewen Callaway

North Korea lets scientists peer inside dangerous volcano pp. 290-291

Alexandra Witze

Multibillion-euro innovation hub slammed by auditors pp. 291-291

Quirin Schiermeier

Synthetic biology tackles global antivenom shortage pp. 292-292

Carrie Arnold

Gene-edited CRISPR mushroom escapes US regulation pp. 293-293

Emily Waltz

Dirty room-mates make lab mice more useful pp. 294-295

Sara Reardon

Cold truths at the top of the world pp. 296-299

Julia Rosen

Monkey kingdom pp. 300-302

David Cyranoski

Track climate pledges of cities and companies pp. 303-306

Angel Hsu, Yaping Cheng, Amy Weinfurter, Kaiyang Xu and Cameron Yick

Peer review: Troubled from the start pp. 306-308

Alex Csiszar

Palaeolithic art: Old masters, early cultures pp. 310-311

Jill Cook

Books in brief pp. 311-311

Barbara Kiser

Autobiography: A lab of one's own pp. 312-312

Jennifer Rohn

Authenticate new xenograft models pp. 313-313

Roland M. Nardone, Roderick A. F. MacLeod and Amanda Capes-Davis

Science primers in the courtroom pp. 313-313

David Baltimore and David S. Tatel

IPBES reaches out to social scientists pp. 313-313

Anne Larigauderie, Marie Stenseke and Robert T. Watson

Self-built labware stimulates creativity pp. 313-313

Pawel Urban

A different take on Indus evidence pp. 313-313

Bryan K. Wells

Geoffrey Eglinton (1927–2016) pp. 314-314

Katherine H. Freeman

Eating for trillions pp. 316-317

Derrick M. Chu and Kjersti M. Aagaard

Misconceptions of global catastrophe pp. 317-318

Joacim Rocklöv

An elusive DNA base in mammals pp. 319-320

Gerd P. Pfeifer

Antidepressants at work pp. 320-321

Marc G. Caron and Ulrik Gether

Organelle stress triggers inflammation pp. 321-322

Bennett H. Penn and Jeffery S. Cox

Distinct bone marrow blood vessels differentially regulate haematopoiesis pp. 323-328

Tomer Itkin, Shiri Gur-Cohen, Joel A. Spencer, Amir Schajnovitz, Saravana K. Ramasamy, Anjali P. Kusumbe, Guy Ledergor, Yookyung Jung, Idan Milo, Michael G. Poulos, Alexander Kalinkovich, Aya Ludin, Karin Golan, Eman Khatib, Anju Kumari, Orit Kollet, Guy Shakhar, Jason M. Butler, Shahin Rafii, Ralf H. Adams, David T. Scadden, Charles P. Lin and Tsvee Lapidot

DNA methylation on N6-adenine in mammalian embryonic stem cells pp. 329-333

Tao P. Wu, Tao Wang, Matthew G. Seetin, Yongquan Lai, Shijia Zhu, Kaixuan Lin, Yifei Liu, Stephanie D. Byrum, Samuel G. Mackintosh, Mei Zhong, Alan Tackett, Guilin Wang, Lawrence S. Hon, Gang Fang, James A. Swenberg and Andrew Z. Xiao

X-ray structures and mechanism of the human serotonin transporter pp. 334-339

Jonathan A. Coleman, Evan M. Green and Eric Gouaux

A 17-billion-solar-mass black hole in a group galaxy with a diffuse core pp. 340-342

Jens Thomas, Chung-Pei Ma, Nicholas J. McConnell, Jenny E. Greene, John P. Blakeslee and Ryan Janish

Detection of a Cooper-pair density wave in Bi2Sr2CaCu2O8+x pp. 343-347

M. H. Hamidian, S. D. Edkins, Sang Hyun Joo, A. Kostin, H. Eisaki, S. Uchida, M. J. Lawler, E.-A. Kim, A. P. Mackenzie, K. Fujita, Jinho Lee and J. C. Séamus Davis

A pressure-amplifying framework material with negative gas adsorption transitions pp. 348-352

Simon Krause, Volodymyr Bon, Irena Senkovska, Ulrich Stoeck, Dirk Wallacher, Daniel M. Többens, Stefan Zander, Renjith S. Pillai, Guillaume Maurin, François-Xavier Coudert and Stefan Kaskel

Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols pp. 353-356

Shi-Liang Shi, Zackary L. Wong and Stephen L. Buchwald

Recent improvement and projected worsening of weather in the United States pp. 357-360

Patrick J. Egan and Megan Mullin

The Parkfield tremors reveal slow and fast ruptures on the same asperity pp. 361-365

Deepa Mele Veedu and Sylvain Barbot

Revised stratigraphy and chronology for Homo floresiensis at Liang Bua in Indonesia pp. 366-369

Thomas Sutikna, Matthew W. Tocheri, Michael J. Morwood, E. Wahyu Saptomo, Jatmiko, Rokus Due Awe, Sri Wasisto, Kira E. Westaway, Maxime Aubert, Bo Li, Jian-xin Zhao, Michael Storey, Brent V. Alloway, Mike W. Morley, Hanneke J. M. Meijer, Gerrit D. van den Bergh, Rainer Grün, Anthony Dosseto, Adam Brumm, William L. Jungers and Richard G. Roberts

Anatomy and function of an excitatory network in the visual cortex pp. 370-374

Wei-Chung Allen Lee, Vincent Bonin, Michael Reed, Brett J. Graham, Greg Hood, Katie Glattfelder and R. Clay Reid

Daily magnesium fluxes regulate cellular timekeeping and energy balance pp. 375-379

Kevin A. Feeney, Louise L. Hansen, Marrit Putker, Consuelo Olivares-Yañez, Jason Day, Lorna J. Eades, Luis F. Larrondo, Nathaniel P. Hoyle, John S. O’Neill and Gerben van Ooijen

Age-dependent modulation of vascular niches for haematopoietic stem cells pp. 380-384

Anjali P. Kusumbe, Saravana K. Ramasamy, Tomer Itkin, Maarja Andaloussi Mäe, Urs H. Langen, Christer Betsholtz, Tsvee Lapidot and Ralf H. Adams

The diversity-generating benefits of a prokaryotic adaptive immune system pp. 385-388

Stineke van Houte, Alice K. E. Ekroth, Jenny M. Broniewski, Hélène Chabas, Ben Ashby, Joseph Bondy-Denomy, Sylvain Gandon, Mike Boots, Steve Paterson, Angus Buckling and Edze R. Westra

Metabolic maintenance of cell asymmetry following division in activated T lymphocytes pp. 389-393

Katherine C. Verbist, Cliff S. Guy, Sandra Milasta, Swantje Liedmann, Marcin M. Kamiński, Ruoning Wang and Douglas R. Green

NOD1 and NOD2 signalling links ER stress with inflammation pp. 394-397

A. Marijke Keestra-Gounder, Mariana X. Byndloss, Núbia Seyffert, Briana M. Young, Alfredo Chávez-Arroyo, April Y. Tsai, Stephanie A. Cevallos, Maria G. Winter, Oanh H. Pham, Connor R. Tiffany, Maarten F. de Jong, Tobias Kerrinnes, Resmi Ravindran, Paul A. Luciw, Stephen J. McSorley, Andreas J. Bäumler and Renée M. Tsolis

USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites pp. 398-401

Byung-Hoon Lee, Ying Lu, Miguel A. Prado, Yuan Shi, Geng Tian, Shuangwu Sun, Suzanne Elsasser, Steven P. Gygi, Randall W. King and Daniel Finley

Correction: Corrigendum: CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase pp. 402-402

Weiwei He, Ge Bai, Huihao Zhou, Na Wei, Nicholas M. White, Janelle Lauer, Huaqing Liu, Yi Shi, Calin Dan Dumitru, Karen Lettieri, Veronica Shubayev, Albena Jordanova, Velina Guergueltcheva, Patrick R. Griffin, Robert W. Burgess, Samuel L. Pfaff and Xiang-Lei Yang

Correction: Corrigendum: D14–SCFD3-dependent degradation of D53 regulates strigolactone signalling pp. 402-402

Feng Zhou, Qibing Lin, Lihong Zhu, Yulong Ren, Kunneng Zhou, Nitzan Shabek, Fuqing Wu, Haibin Mao, Wei Dong, Lu Gan, Weiwei Ma, He Gao, Jun Chen, Chao Yang, Dan Wang, Junjie Tan, Xin Zhang, Xiuping Guo, Jiulin Wang, Ling Jiang, Xi Liu, Weiqi Chen, Jinfang Chu, Cunyu Yan, Kotomi Ueno, Shinsaku Ito, Tadao Asami, Zhijun Cheng, Jie Wang, Cailin Lei, Huqu Zhai, Chuanyin Wu, Haiyang Wang, Ning Zheng and Jianmin Wan

Erratum: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation pp. 402-402

Ingrid E. Wertz, Kim Newton, Dhaya Seshasayee, Saritha Kusam, Cynthia Lam, Juan Zhang, Nataliya Popovych, Elizabeth Helgason, Allyn Schoeffler, Surinder Jeet, Nandhini Ramamoorthi, Lorna Kategaya, Robert J. Newman, Keisuke Horikawa, Debra Dugger, Wendy Sandoval, Susmith Mukund, Anuradha Zindal, Flavius Martin, Clifford Quan, Jeffrey Tom, Wayne J. Fairbrother, Michael Townsend, Søren Warming, Jason DeVoss, Jinfeng Liu, Erin Dueber, Patrick Caplazi, Wyne P. Lee, Christopher C. Goodnow, Mercedesz Balazs, Kebing Yu, Ganesh Kolumam and Vishva M. Dixit

Ecology: Change is in the air pp. 403-404

Barbra Rodriguez

How to survive as a whistle-blower pp. 405-405

Michael Doran

The parasite and the widow pp. 408-408

Jeremy M. Gottwig

2016, volume 532, articles 7598

Origins of the obesity pandemic can be analysed pp. 149-149

John Frank

Fears rise over yellow fever’s next move pp. 155-156

Declan Butler

Rescued Japanese spacecraft delivers first results from Venus pp. 157-158

Elizabeth Gibney

Gene-editing surges as US rethinks regulations pp. 158-159

Heidi Ledford

How one lab challenged a grant rejection and won €5 million pp. 159-160

Ewen Callaway

Human mind excels at quantum-physics computer game pp. 160-161

Elizabeth Gibney

Cocktails for cancer with a measure of immunotherapy pp. 162-164

Heidi Ledford

Cancer therapy: an evolved approach pp. 166-168

Cassandra Willyard

Physics: Unite to build a quantum Internet pp. 169-171

Stefano Pirandola and Samuel L. Braunstein

CRISPR: Pursuit of profit poisons collaboration pp. 172-173

Jacob S. Sherkow

Ornithology: Oology unshelled pp. 174-175

John M. Marzluff

Books in brief pp. 175-175

Barbara Kiser

Evolution: Taxonomies of cognition pp. 176-176

Joan B. Silk

Climate costing is politics not science pp. 177-177

Andrea Saltelli

Europe must block hornet invasion pp. 177-177

Frederico Santarém

Software for study design falls short pp. 177-177

David K. Meyerholz and Alessandra Piersigilli

Silver lining to irreproducibility pp. 177-177

Alyssa Ward, Thomas O. Baldwin and Parker B. Antin

Social cooperation among agnostics pp. 177-177

Jeroen Bruggeman

Lloyd Shapley (1923–2016) pp. 178-178

Alvin Roth

Some begging is actually bragging pp. 180-181

Douglas W. Mock

Hard-to-reach repairs pp. 181-182

Ekta Khurana

Not everything is scary about a glial scar pp. 182-183

Shane A. Liddelow and Ben A. Barres

RETRACTED ARTICLE: Quantum problems solved through games pp. 184-185

Sabrina Maniscalco

Surprises from the sanitary engineers pp. 185-186

Richard M. Ransohoff

How rain affects rock and rivers pp. 186-187

Alison M. Anders

Hourglass fermions pp. 189-194

Zhijun Wang, A. Alexandradinata, R. J. Cava and B. Andrei Bernevig

Astrocyte scar formation aids central nervous system axon regeneration pp. 195-200

Mark A. Anderson, Joshua E. Burda, Yilong Ren, Yan Ao, Timothy M. O’Shea, Riki Kawaguchi, Giovanni Coppola, Baljit S. Khakh, Timothy J. Deming and Michael V. Sofroniew

Modulation of tissue repair by regeneration enhancer elements pp. 201-206

Junsu Kang, Jianxin Hu, Ravi Karra, Amy L. Dickson, Valerie A. Tornini, Gregory Nachtrab, Matthew Gemberling, Joseph A. Goldman, Brian L. Black and Kenneth D. Poss

A map of the large day–night temperature gradient of a super-Earth exoplanet pp. 207-209

Brice-Olivier Demory, Michael Gillon, Julien de Wit, Nikku Madhusudhan, Emeline Bolmont, Kevin Heng, Tiffany Kataria, Nikole Lewis, Renyu Hu, Jessica Krick, Vlada Stamenković, Björn Benneke, Stephen Kane and Didier Queloz

Exploring the quantum speed limit with computer games pp. 210-213

Jens Jakob W. H. Sørensen, Mads Kock Pedersen, Michael Munch, Pinja Haikka, Jesper Halkjær Jensen, Tilo Planke, Morten Ginnerup Andreasen, Miroslav Gajdacz, Klaus Mølmer, Andreas Lieberoth and Jacob F. Sherson

Direct observation of dynamic shear jamming in dense suspensions pp. 214-217

Ivo R. Peters, Sayantan Majumdar and Heinrich M. Jaeger

Asymmetric catalytic formation of quaternary carbons by iminium ion trapping of radicals pp. 218-222

John J. Murphy, David Bastida, Suva Paria, Maurizio Fagnoni and Paolo Melchiorre

Chemical weathering as a mechanism for the climatic control of bedrock river incision pp. 223-227

Brendan P. Murphy, Joel P. L. Johnson, Nicole M. Gasparini and Leonard S. Sklar

Ritual human sacrifice promoted and sustained the evolution of stratified societies pp. 228-231

Joseph Watts, Oliver Sheehan, Quentin D. Atkinson, Joseph Bulbulia and Russell D. Gray

Post-invasion demography of prehistoric humans in South America pp. 232-235

Amy Goldberg, Alexis M. Mychajliw and Elizabeth A. Hadly

A neuronal circuit for colour vision based on rod–cone opponency pp. 236-239

Maximilian Joesch and Markus Meister

TAM receptors regulate multiple features of microglial physiology pp. 240-244

Lawrence Fourgeaud, Paqui G. Través, Yusuf Tufail, Humberto Leal-Bailey, Erin D. Lew, Patrick G. Burrola, Perri Callaway, Anna Zagórska, Carla V. Rothlin, Axel Nimmerjahn and Greg Lemke

The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression pp. 245-249

Lena Seifert, Gregor Werba, Shaun Tiwari, Nancy Ngoc Giao Ly, Sara Alothman, Dalia Alqunaibit, Antonina Avanzi, Rocky Barilla, Donnele Daley, Stephanie H. Greco, Alejandro Torres-Hernandez, Matthew Pergamo, Atsuo Ochi, Constantinos P. Zambirinis, Mridul Pansari, Mauricio Rendon, Daniel Tippens, Mautin Hundeyin, Vishnu R. Mani, Cristina Hajdu, Dannielle Engle and George Miller

sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance pp. 250-254

Amanpreet Kaur, Marie R. Webster, Katie Marchbank, Reeti Behera, Abibatou Ndoye, Curtis H. Kugel, Vanessa M. Dang, Jessica Appleton, Michael P. O’Connell, Phil Cheng, Alexander A. Valiga, Rachel Morissette, Nazli B. McDonnell, Luigi Ferrucci, Andrew V. Kossenkov, Katrina Meeth, Hsin-Yao Tang, Xiangfan Yin, William H. Wood, Elin Lehrmann, Kevin G. Becker, Keith T. Flaherty, Dennie T. Frederick, Jennifer A. Wargo, Zachary A. Cooper, Michael T. Tetzlaff, Courtney Hudgens, Katherine M. Aird, Rugang Zhang, Xiaowei Xu, Qin Liu, Edmund Bartlett, Giorgos Karakousis, Zeynep Eroglu, Roger S. Lo, Matthew Chan, Alexander M. Menzies, Georgina V. Long, Douglas B. Johnson, Jeffrey Sosman, Bastian Schilling, Dirk Schadendorf, David W. Speicher, Marcus Bosenberg, Antoni Ribas and Ashani T. Weeraratna

Reductive carboxylation supports redox homeostasis during anchorage-independent growth pp. 255-258

Lei Jiang, Alexander A. Shestov, Pamela Swain, Chendong Yang, Seth J. Parker, Qiong A. Wang, Lance S. Terada, Nicholas D. Adams, Michael T. McCabe, Beth Pietrak, Stan Schmidt, Christian M. Metallo, Brian P. Dranka, Benjamin Schwartz and Ralph J. DeBerardinis

Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes pp. 259-263

Dilmi Perera, Rebecca C. Poulos, Anushi Shah, Dominik Beck, John E. Pimanda and Jason W. H. Wong

Nucleotide excision repair is impaired by binding of transcription factors to DNA pp. 264-267

Radhakrishnan Sabarinathan, Loris Mularoni, Jordi Deu-Pons, Abel Gonzalez-Perez and Núria López-Bigas

Correction: Corrigendum: Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart pp. 268-268

Wataru Kimura, Feng Xiao, Diana C. Canseco, Shalini Muralidhar, SuWannee Thet, Helen M. Zhang, Yezan Abderrahman, Rui Chen, Joseph A. Garcia, John M. Shelton, James A. Richardson, Abdelrahman M. Ashour, Aroumougame Asaithamby, Hanquan Liang, Chao Xing, Zhigang Lu, Cheng Cheng Zhang and Hesham A. Sadek

Correction: Corrigendum: Mapping tree density at a global scale pp. 268-268

T. W. Crowther, H. B. Glick, K. R. Covey, C. Bettigole, D. S. Maynard, S. M. Thomas, J. R. Smith, G. Hintler, M. C. Duguid, G. Amatulli, M.-N. Tuanmu, W. Jetz, C. Salas, C. Stam, D. Piotto, R. Tavani, S. Green, G. Bruce, S. J. Williams, S. K. Wiser, M. O. Huber, G. M. Hengeveld, G.-J. Nabuurs, E. Tikhonova, P. Borchardt, C.-F. Li, L. W. Powrie, M. Fischer, A. Hemp, J. Homeier, P. Cho, A. C. Vibrans, P. M. Umunay, S. L. Piao, C. W. Rowe, M. S. Ashton, P. R. Crane and M. A. Bradford

Retraction Note: The structure of complement C3b provides insights into complement activation and regulation pp. 268-268

A. Abdul Ajees, K. Gunasekaran, John E. Volanakis, Sthanam. V. L. Narayana, Girish J. Kotwal and H. M. Krishna Murthy

The tumour trail left in blood pp. 269-271

Kelly Rae Chi

Biomedical research: Privacy rules pp. 273-274

Alaina Levine

Trade talk: Serial solver pp. 274-274

Monya Baker

Incursions pp. 276-276

Lavie Tidhar

2016, volume 532, articles 7597

Recognize the value of social science pp. 7-7

Andrew Webster

Trump’s immigration stance stokes fears for science pp. 13-14

Heidi Ledford

Controversial dark-matter claim faces ultimate test pp. 14-15

Davide Castelvecchi

Zika highlights role of controversial fetal-tissue research pp. 16-16

Erika Check Hayden

Snow-sensing fleet to unlock water's icy secrets pp. 17-17

Alexandra Witze

Negotiations to tame marine Wild West begin pp. 18-19

Daniel Cressey

Flagship brain project releases neuro-computing tools pp. 18-18

Quirin Schiermeier and Alison Abbott

Mental health: There’s an app for that pp. 20-23

Emily Anthes

Action on mental health needs global cooperation pp. 25-27

Pamela Y. Collins and Shekhar Saxena

Physics: Soundtrack of the Universe pp. 28-29

Sheila Rowan

New in paperback pp. 30-30

Emily Banham

Meteorology: The brainstormers pp. 30-31

Alan Thorpe

Energy: Oilman at the peak pp. 31-32

Gregor Macdonald

Neuroscience: Listening in on yourself pp. 32-33

Douwe Draaisma

Space science: The women who launched NASA pp. 34-35

Jennifer Light

Genetics: Coitus defunctus pp. 35-36

Lori Andrews

Embed stormwater use in city planning pp. 37-37

Shunsuke Managi, Ashantha Goonetilleke and Clevo Wilson

Engage engineers in soil management pp. 37-37

Karen L. Johnson

A global baseline for ecosystem recovery pp. 37-37

Janne S. Kotiaho, Ben ten Brink and Jim Harris

Holistic hydropower scheme for China pp. 37-37

Wenzhe Tang

Supernovae in the neighbourhood pp. 40-41

Adrian L. Melott

Fungus produces a toxic surprise pp. 41-42

Aaron P. Mitchell

Shaped by sea-level shifts pp. 42-43

José María Fernández-Palacios

Water's past revisited to predict its future pp. 44-45

Matthew E. Kirby

Untangling autism pp. 45-46

Scott Bolkan and Joshua A. Gordon

Breaks in the brain pp. 46-47

Thomas W. Glover and Thomas E. Wilson

Climate-smart soils pp. 49-57

Keith Paustian, Johannes Lehmann, Stephen Ogle, David Reay, G. Philip Robertson and Pete Smith

Thalamic reticular impairment underlies attention deficit in Ptchd1Y/− mice pp. 58-63

Michael F. Wells, Ralf D. Wimmer, L. Ian Schmitt, Guoping Feng and Michael M. Halassa

Candidalysin is a fungal peptide toxin critical for mucosal infection pp. 64-68

David L. Moyes, Duncan Wilson, Jonathan P. Richardson, Selene Mogavero, Shirley X. Tang, Julia Wernecke, Sarah Höfs, Remi L. Gratacap, Jon Robbins, Manohursingh Runglall, Celia Murciano, Mariana Blagojevic, Selvam Thavaraj, Toni M. Förster, Betty Hebecker, Lydia Kasper, Gema Vizcay, Simona I. Iancu, Nessim Kichik, Antje Häder, Oliver Kurzai, Ting Luo, Thomas Krüger, Olaf Kniemeyer, Ernesto Cota, Oliver Bader, Robert T. Wheeler, Thomas Gutsmann, Bernhard Hube and Julian R. Naglik

Recent near-Earth supernovae probed by global deposition of interstellar radioactive 60Fe pp. 69-72

A. Wallner, J. Feige, N. Kinoshita, M. Paul, L. K. Fifield, R. Golser, M. Honda, U. Linnemann, H. Matsuzaki, S. Merchel, G. Rugel, S. G. Tims, P. Steier, T. Yamagata and S. R. Winkler

The locations of recent supernovae near the Sun from modelling 60Fe transport pp. 73-76

D. Breitschwerdt, J. Feige, M. M. Schulreich, M. A. de. Avillez, C. Dettbarn and B. Fuchs

Coherent feedback control of a single qubit in diamond pp. 77-80

Masashi Hirose and Paola Cappellaro

Quantum hydrogen-bond symmetrization in the superconducting hydrogen sulfide system pp. 81-84

Ion Errea, Matteo Calandra, Chris J. Pickard, Joseph R. Nelson, Richard J. Needs, Yinwei Li, Hanyu Liu, Yunwei Zhang, Yanming Ma and Francesco Mauri

Continuous directional water transport on the peristome surface of Nepenthes alata pp. 85-89

Huawei Chen, Pengfei Zhang, Liwen Zhang, Hongliang Liu, Ying Jiang, Deyuan Zhang, Zhiwu Han and Lei Jiang

Nineteen-step total synthesis of (+)-phorbol pp. 90-93

Shuhei Kawamura, Hang Chu, Jakob Felding and Phil S. Baran

Northern Hemisphere hydroclimate variability over the past twelve centuries pp. 94-98

Fredrik Charpentier Ljungqvist, Paul J. Krusic, Hanna S. Sundqvist, Eduardo Zorita, Gudrun Brattström and David Frank

Late Quaternary climate change shapes island biodiversity pp. 99-102

Patrick Weigelt, Manuel Jonas Steinbauer, Juliano Sarmento Cabral and Holger Kreft

A specific area of olfactory cortex involved in stress hormone responses to predator odours pp. 103-106

Kunio Kondoh, Zhonghua Lu, Xiaolan Ye, David P. Olson, Bradford B. Lowell and Linda B. Buck

Derivation and differentiation of haploid human embryonic stem cells pp. 107-111

Ido Sagi, Gloryn Chia, Tamar Golan-Lev, Mordecai Peretz, Uri Weissbein, Lina Sui, Mark V. Sauer, Ofra Yanuka, Dieter Egli and Nissim Benvenisty

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1 pp. 112-116

Edward T. Chouchani, Lawrence Kazak, Mark P. Jedrychowski, Gina Z. Lu, Brian K. Erickson, John Szpyt, Kerry A. Pierce, Dina Laznik-Bogoslavski, Ramalingam Vetrivelan, Clary B. Clish, Alan J. Robinson, Steve P. Gygi and Bruce M. Spiegelman

Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia pp. 117-121

Ryu Okumura, Takashi Kurakawa, Takashi Nakano, Hisako Kayama, Makoto Kinoshita, Daisuke Motooka, Kazuyoshi Gotoh, Taishi Kimura, Naganori Kamiyama, Takashi Kusu, Yoshiyasu Ueda, Hong Wu, Hideki Iijima, Soumik Barman, Hideki Osawa, Hiroshi Matsuno, Junichi Nishimura, Yusuke Ohba, Shota Nakamura, Tetsuya Iida, Masahiro Yamamoto, Eiji Umemoto, Koichi Sano and Kiyoshi Takeda

Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling pp. 122-126

Zinan Zhou, Alan T. Tang, Weng-Yew Wong, Sharika Bamezai, Lauren M. Goddard, Robert Shenkar, Su Zhou, Jisheng Yang, Alexander C. Wright, Matthew Foley, J. Simon C. Arthur, Kevin J. Whitehead, Issam A. Awad, Dean Y. Li, Xiangjian Zheng and Mark L. Kahn

Structural basis of lenalidomide-induced CK1α degradation by the CRL4CRBN ubiquitin ligase pp. 127-130

Georg Petzold, Eric S. Fischer and Nicolas H. Thomä

Structural basis of cohesin cleavage by separase pp. 131-134

Zhonghui Lin, Xuelian Luo and Hongtao Yu

Robots record brain activity inside neurons pp. 135-136

Helen Shen

Web widget nudges scientists to share their data pp. 136-136

Dalmeet Singh Chawla

Disability awareness: The fight for accessibility pp. 137-139

Eryn Brown

Choices, in sequential order pp. 142-142

Karlo Yeager Rodríguez