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2016, volume 530, articles 7591

Can today’s decisions really be future-proofed? pp. 383-383

Céline Kermisch

Synthetic biology’s first malaria drug meets market resistance pp. 389-390

Mark Peplow

US cancer institute to overhaul tumour cell lines pp. 391-391

Heidi Ledford

Satellite alerts track deforestation in real time pp. 392-393

Gabriel Popkin

Polish scientists protest over plan to log in Białowieża Forest pp. 393-393

Quirin Schiermeier

Modern Milgram experiment sheds light on power of authority pp. 394-395

Alison Abbott

Proposal to ban imported monkeys catches scientists off guard pp. 394-394

Bianca Nogrady

A world where everyone has a robot: why 2040 could blow your mind pp. 398-401

Declan Butler

Should you edit your children’s genes? pp. 402-405

Erika Check Hayden

Economics: Current climate models are grossly misleading pp. 407-409

Nicholas Stern

Development: Slow down population growth pp. 409-412

John Bongaarts

Sustainability: Game human nature pp. 413-415

Helga Fehr-Duda and Ernst Fehr

Evolution: Doing the locomotion pp. 416-417

Kevin Padian

Books in brief pp. 417-417

Barbara Kiser

History of science: When eugenics became law pp. 418-418

Victoria Nourse

Starlings' patterns are not spontaneous pp. 419-419

John Skoyles

Ancient forest: spare it from clearance pp. 419-419

Przemysław Chylarecki and Nuria Selva

Ancient forest: keep the logging ban pp. 419-419

Pawel Michalak

Cochrane reviews expose bias too pp. 419-419

Kay Dickersin and Tianjing Li

That's quite a collection pp. 419-419

Rick Borchelt

Antigen-specific immunotherapy pp. 422-423

David Wraith

A new methyl mark on messengers pp. 423-424

Anna M. Kietrys and Eric T. Kool

What teeth tell us pp. 425-426

Aida Gómez-Robles

Hidden trends in the ocean carbon sink pp. 426-427

Tatiana Ilyina

Home of a fast radio burst pp. 427-428

Duncan Lorimer

Ancient gene flow from early modern humans into Eastern Neanderthals pp. 429-433

Martin Kuhlwilm, Ilan Gronau, Melissa J. Hubisz, Cesare de Filippo, Javier Prado-Martinez, Martin Kircher, Qiaomei Fu, Hernán A. Burbano, Carles Lalueza-Fox, Marco de la Rasilla, Antonio Rosas, Pavao Rudan, Dejana Brajkovic, Željko Kucan, Ivan Gušic, Tomas Marques-Bonet, Aida M. Andrés, Bence Viola, Svante Pääbo, Matthias Meyer, Adam Siepel and Sergi Castellano

Expanding antigen-specific regulatory networks to treat autoimmunity pp. 434-440

Xavier Clemente-Casares, Jesus Blanco, Poornima Ambalavanan, Jun Yamanouchi, Santiswarup Singha, Cesar Fandos, Sue Tsai, Jinguo Wang, Nahir Garabatos, Cristina Izquierdo, Smriti Agrawal, Michael B. Keough, V. Wee Yong, Eddie James, Anna Moore, Yang Yang, Thomas Stratmann, Pau Serra and Pere Santamaria

The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA pp. 441-446

Dan Dominissini, Sigrid Nachtergaele, Sharon Moshitch-Moshkovitz, Eyal Peer, Nitzan Kol, Moshe Shay Ben-Haim, Qing Dai, Ayelet Di Segni, Mali Salmon-Divon, Wesley C. Clark, Guanqun Zheng, Tao Pan, Oz Solomon, Eran Eyal, Vera Hershkovitz, Dali Han, Louis C. Doré, Ninette Amariglio, Gideon Rechavi and Chuan He

Structural basis for activity regulation of MLL family methyltransferases pp. 447-452

Yanjing Li, Jianming Han, Yuebin Zhang, Fang Cao, Zhijun Liu, Shuai Li, Jian Wu, Chunyi Hu, Yan Wang, Jin Shuai, Juan Chen, Liaoran Cao, Dangsheng Li, Pan Shi, Changlin Tian, Jian Zhang, Yali Dou, Guohui Li, Yong Chen and Ming Lei

The host galaxy of a fast radio burst pp. 453-456

E. F. Keane, S. Johnston, S. Bhandari, E. Barr, N. D. R. Bhat, M. Burgay, M. Caleb, C. Flynn, A. Jameson, M. Kramer, E. Petroff, A. Possenti, W. van Straten, M. Bailes, S. Burke-Spolaor, R. P. Eatough, B. W. Stappers, T. Totani, Masayoshi Honma, H. Furusawa, T. Hattori, T. Morokuma, Y. Niino, H. Sugai, T. Terai, N. Tominaga, S. Yamasaki, N. Yasuda, R. Allen, J. Cooke, J. Jencson, M. M. Kasliwal, D. L. Kaplan, S. J. Tingay, A. Williams, R. Wayth, P. Chandra, D. Perrodin, M. Berezina, M. Mickaliger and C. Bassa

Non-destructive state detection for quantum logic spectroscopy of molecular ions pp. 457-460

Fabian Wolf, Yong Wan, Jan C. Heip, Florian Gebert, Chunyan Shi and Piet O. Schmidt

Possible light-induced superconductivity in K3C60 at high temperature pp. 461-464

M. Mitrano, A. Cantaluppi, D. Nicoletti, S. Kaiser, A. Perucchi, S. Lupi, P. Di Pietro, D. Pontiroli, M. Riccò, S. R. Clark, D. Jaksch and A. Cavalleri

A pentanuclear iron catalyst designed for water oxidation pp. 465-468

Masaya Okamura, Mio Kondo, Reiko Kuga, Yuki Kurashige, Takeshi Yanai, Shinya Hayami, Vijayendran K. K. Praneeth, Masaki Yoshida, Ko Yoneda, Satoshi Kawata and Shigeyuki Masaoka

Timescales for detection of trends in the ocean carbon sink pp. 469-472

Galen A. McKinley, Darren J. Pilcher, Amanda R. Fay, Keith Lindsay, Matthew C. Long and Nicole S. Lovenduski

Third-party punishment as a costly signal of trustworthiness pp. 473-476

Jillian J. Jordan, Moshe Hoffman, Paul Bloom and David G. Rand

A simple rule governs the evolution and development of hominin tooth size pp. 477-480

Alistair R. Evans, E. Susanne Daly, Kierstin K. Catlett, Kathleen S. Paul, Stephen J. King, Matthew M. Skinner, Hans P. Nesse, Jean-Jacques Hublin, Grant C. Townsend, Gary T. Schwartz and Jukka Jernvall

Adult restoration of Shank3 expression rescues selective autistic-like phenotypes pp. 481-484

Yuan Mei, Patricia Monteiro, Yang Zhou, Jin-Ah Kim, Xian Gao, Zhanyan Fu and Guoping Feng

Inhibiting fungal multidrug resistance by disrupting an activator–Mediator interaction pp. 485-489

Joy L. Nishikawa, Andras Boeszoermenyi, Luis A. Vale-Silva, Riccardo Torelli, Brunella Posteraro, Yoo-Jin Sohn, Fei Ji, Vladimir Gelev, Dominique Sanglard, Maurizio Sanguinetti, Ruslan I. Sadreyev, Goutam Mukherjee, Jayaram Bhyravabhotla, Sara J. Buhrlage, Nathanael S. Gray, Gerhard Wagner, Anders M. Näär and Haribabu Arthanari

Tumour-specific proline vulnerability uncovered by differential ribosome codon reading pp. 490-494

Fabricio Loayza-Puch, Koos Rooijers, Levi C. M. Buil, Jelle Zijlstra, Joachim F. Oude Vrielink, Rui Lopes, Alejandro Pineiro Ugalde, Pieter van Breugel, Ingrid Hofland, Jelle Wesseling, Olaf van Tellingen, Axel Bex and Reuven Agami

Epithelial tricellular junctions act as interphase cell shape sensors to orient mitosis pp. 495-498

Floris Bosveld, Olga Markova, Boris Guirao, Charlotte Martin, Zhimin Wang, Anaëlle Pierre, Maria Balakireva, Isabelle Gaugue, Anna Ainslie, Nicolas Christophorou, David K. Lubensky, Nicolas Minc and Yohanns Bellaïche

Structural basis for promiscuous PAM recognition in type I–E Cascade from E. coli pp. 499-503

Robert P. Hayes, Yibei Xiao, Fran Ding, Paul B. G. van Erp, Kanagalaghatta Rajashankar, Scott Bailey, Blake Wiedenheft and Ailong Ke

Correction: Corrigendum: NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells pp. 504-504

Stephanie C. Eisenbarth, Adam Williams, Oscar R. Colegio, Hailong Meng, Till Strowig, Anthony Rongvaux, Jorge Henao-Mejia, Christoph A. Thaiss, Sophie Joly, David G. Gonzalez, Lan Xu, Lauren A. Zenewicz, Ann M. Haberman, Eran Elinav, Steven H. Kleinstein, Fayyaz S. Sutterwala and Richard A. Flavell

Activism: Frustrated postdocs rise up pp. 505-506

Paul Smaglik

Changes on the ice pp. 507-507

Robin Bell

Duck, duck, duck pp. 510-510

Samantha Murray

2016, volume 530, articles 7590

Put innovation science at the heart of discovery pp. 255-255

Andrew Kusiak

Researchers debate whether female computer coders face bias pp. 257-257

Dalmeet Singh Chawla

Gravitational waves: How LIGO forged the path to victory pp. 261-262

Davide Castelvecchi

Young scientists poised to ride the gravitational wave pp. 263-263

Alexandra Witze

A mouse’s house may ruin experiments pp. 264-264

Sara Reardon

Biologists urged to hug a preprint pp. 265-265

Ewen Callaway and Kendall Powell

UN agency proposes greenhouse-gas standard for aircraft pp. 266-266

Jeff Tollefson

New Delhi car ban yields trove of pollution data pp. 266-267

Meera Subramanian

What sparked the Cambrian explosion? pp. 268-270

Douglas Fox

The truth about exoplanets pp. 272-274

Jeff Hecht

Pollution: Three steps to a green shipping industry pp. 275-277

Zheng Wan, Mo Zhu, Shun Chen and Daniel Sperling

Physics: Radiant realms pp. 278-279

Philip Ball

Engineering: Broken bridges and highways from hell pp. 279-280

Kyle Shelton

Technology alone won't save climate pp. 281-281

Julian Allwood

Formalize recycling of electronic waste pp. 281-281

Devika Kannan, Kannan Govindan and Madan Shankar

International accord on open data pp. 281-281

Geoffrey Boulton

Control wildlife pathogens too pp. 281-281

Helen Roy

Weapons plutonium riskier above ground pp. 281-281

Edwin Lyman and Frank von Hippel

Marvin L. Minsky (1927–2016) pp. 282-282

Patrick Henry Winston

Photons paired with phonons pp. 284-285

Miles Blencowe

Hand of the gods in human civilization pp. 285-286

Dominic D. P. Johnson

Ice streams waned as ice sheets shrank pp. 287-288

Jason P. Briner

Form follows function for mitochondria pp. 288-289

Chunxin Wang and Richard Youle

Females have a lot of guts pp. 289-290

Justin Fear and Brian Oliver

From sea to sea pp. 290-291

Susan L. Williams

The peptidergic control circuit for sighing pp. 293-297

Peng Li, Wiktor A. Janczewski, Kevin Yackle, Kaiwen Kam, Silvia Pagliardini, Mark A. Krasnow and Jack L. Feldman

Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution pp. 298-302

Thi Hoang Duong Nguyen, Wojciech P. Galej, Xiao-chen Bai, Chris Oubridge, Andrew J. Newman, Sjors H. W. Scheres and Kiyoshi Nagai

Super-catastrophic disruption of asteroids at small perihelion distances pp. 303-306

Mikael Granvik, Alessandro Morbidelli, Robert Jedicke, Bryce Bolin, William F. Bottke, Edward Beshore, David Vokrouhlický, Marco Delbò and Patrick Michel

Universal resilience patterns in complex networks pp. 307-312

Jianxi Gao, Baruch Barzel and Albert-László Barabási

Non-classical correlations between single photons and phonons from a mechanical oscillator pp. 313-316

Ralf Riedinger, Sungkun Hong, Richard A. Norte, Joshua A. Slater, Juying Shang, Alexander G. Krause, Vikas Anant, Markus Aspelmeyer and Simon Gröblacher

Uranium-mediated electrocatalytic dihydrogen production from water pp. 317-321

Dominik P. Halter, Frank W. Heinemann, Julien Bachmann and Karsten Meyer

Ice stream activity scaled to ice sheet volume during Laurentide Ice Sheet deglaciation pp. 322-326

C. R. Stokes, M. Margold, C. D. Clark and L. Tarasov

Moralistic gods, supernatural punishment and the expansion of human sociality pp. 327-330

Benjamin Grant Purzycki, Coren Apicella, Quentin D. Atkinson, Emma Cohen, Rita Anne McNamara, Aiyana K. Willard, Dimitris Xygalatas, Ara Norenzayan and Joseph Henrich

The genome of the seagrass Zostera marina reveals angiosperm adaptation to the sea pp. 331-335

Jeanine L. Olsen, Pierre Rouzé, Bram Verhelst, Yao-Cheng Lin, Till Bayer, Jonas Collen, Emanuela Dattolo, Emanuele De Paoli, Simon Dittami, Florian Maumus, Gurvan Michel, Anna Kersting, Chiara Lauritano, Rolf Lohaus, Mats Töpel, Thierry Tonon, Kevin Vanneste, Mojgan Amirebrahimi, Janina Brakel, Christoffer Boström, Mansi Chovatia, Jane Grimwood, Jerry W. Jenkins, Alexander Jueterbock, Amy Mraz, Wytze T. Stam, Hope Tice, Erich Bornberg-Bauer, Pamela J. Green, Gareth A. Pearson, Gabriele Procaccini, Carlos M. Duarte, Jeremy Schmutz, Thorsten B. H. Reusch and Yves Van de Peer

Polygenic evolution of a sugar specialization trade-off in yeast pp. 336-339

Jeremy I. Roop, Kyu Chul Chang and Rachel B. Brem

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche pp. 340-343

Henner F. Farin, Ingrid Jordens, Mohammed H. Mosa, Onur Basak, Jeroen Korving, Daniele V. F. Tauriello, Karin de Punder, Stephane Angers, Peter J. Peters, Madelon M. Maurice and Hans Clevers

The sexual identity of adult intestinal stem cells controls organ size and plasticity pp. 344-348

Bruno Hudry, Sanjay Khadayate and Irene Miguel-Aliaga

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid pp. 349-353

Christian Schläger, Henrike Körner, Martin Krueger, Stefano Vidoli, Michael Haberl, Dorothee Mielke, Elke Brylla, Thomas Issekutz, Carlos Cabañas, Peter J. Nelson, Tjalf Ziemssen, Veit Rohde, Ingo Bechmann, Dmitri Lodygin, Francesca Odoardi and Alexander Flügel

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux pp. 354-357

Yuan He, Melody Y. Zeng, Dahai Yang, Benny Motro and Gabriel Núñez

Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function pp. 358-361

Allison Ballandras-Colas, Monica Brown, Nicola J. Cook, Tamaria G. Dewdney, Borries Demeler, Peter Cherepanov, Dmitry Lyumkis and Alan N. Engelman

Crystal structure of the Rous sarcoma virus intasome pp. 362-366

Zhiqi Yin, Ke Shi, Surajit Banerjee, Krishan K. Pandey, Sibes Bera, Duane P. Grandgenett and Hideki Aihara

DNA tags help the hunt for drugs pp. 367-369

Asher Mullard

Geoscience: Ups and downs pp. 371-372

Virginia Gewin

Turning point: Reproducibility pro pp. 373-373

Monya Baker

Chrysalis pp. 376-376

Andrea Kriz

2016, volume 530, articles 7589

Change the system to halt harassment pp. 131-131

Joan Schmelz

“A field of crop scientists” — Twitter delivers collective nouns for researchers pp. 133-133

Dalmeet Singh Chawla

Tasmanian bushfires threaten iconic ancient forests pp. 137-138

Emma Marris

How should science funders deal with sexual harassers? pp. 138-139

Alexandra Witze

High stakes as Japanese space observatory prepares for launch pp. 140-141

Davide Castelvecchi

Biotech giant publishes failures to confirm high-profile science pp. 141-141

Monya Baker

US panel greenlights creation of male 'three-person' embryos pp. 142-142

Sara Reardon

Proving Zika link to birth defects poses huge challenge pp. 142-143

Erika Check Hayden

The chips are down for Moore’s law pp. 144-147

M. Mitchell Waldrop

Does it take too long to publish research? pp. 148-151

Kendall Powell

Emissions reduction: Scrutinize CO2 removal methods pp. 153-155

Phil Williamson

Global warming: Shareholders must vote for climate-change mitigation pp. 156-156

Howard Covington, James Thornton and Cameron Hepburn

Drug discovery: A life of tumult and triumph pp. 157-158

Marian Turner

Astronomy: Topology quest pp. 158-159

Michael Blanton

Books in brief pp. 159-159

Barbara Kiser

When brain bullets met crowdfunding pp. 160-160

Caroline Apra, Pierre Bourdillon and Marc Lévêque

IPBES disciplinary gaps still gaping pp. 160-160

Alice B. M. Vadrot, Jens Jetzkowitz and Lindsay C. Stringer

More to fisheries than catch limits pp. 160-160

John Casey, Jann T. Martinsohn and Hendrik Dörner

Metrics needed to track adaptation pp. 160-160

Alexandre K. Magnan

From genetics to physiology at last pp. 162-163

Ryan S. Dhindsa and David B. Goldstein

A great Arctic ice shelf pp. 163-164

Eugene Domack

Out with the old pp. 164-165

Jesús Gil and Dominic J. Withers

Compact coupling for a two-stage accelerator pp. 165-166

Brigitte Cros

Asymmetric breaks in DNA cause sterility pp. 167-168

Jiri Forejt

Sequencing on the ground pp. 167-167

Marian Turner

Resolution beyond the diffraction limit pp. 168-169

Jian-Ren Shen

Exoplanets hidden in the gaps pp. 169-170

Paul Ho

Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice pp. 171-176

Benjamin Davies, Edouard Hatton, Nicolas Altemose, Julie G. Hussin, Florencia Pratto, Gang Zhang, Anjali Gupta Hinch, Daniela Moralli, Daniel Biggs, Rebeca Diaz, Chris Preece, Ran Li, Emmanuelle Bitoun, Kevin Brick, Catherine M. Green, R. Daniel Camerini-Otero, Simon R. Myers and Peter Donnelly

Schizophrenia risk from complex variation of complement component 4 pp. 177-183

Aswin Sekar, Allison R. Bialas, Heather de Rivera, Avery Davis, Timothy R. Hammond, Nolan Kamitaki, Katherine Tooley, Jessy Presumey, Matthew Baum, Vanessa Van Doren, Giulio Genovese, Samuel A. Rose, Robert E. Handsaker, Mark J. Daly, Michael C. Carroll, Beth Stevens and Steven A. McCarroll

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan pp. 184-189

Darren J. Baker, Bennett G. Childs, Matej Durik, Melinde E. Wijers, Cynthia J. Sieben, Jian Zhong, Rachel A. Saltness, Karthik B. Jeganathan, Grace Casaclang Verzosa, Abdulmohammad Pezeshki, Khashayarsha Khazaie, Jordan D. Miller and Jan M. van Deursen

Multistage coupling of independent laser-plasma accelerators pp. 190-193

S. Steinke, J. van Tilborg, C. Benedetti, C. G. R. Geddes, C. B. Schroeder, J. Daniels, K. K. Swanson, A. J. Gonsalves, K. Nakamura, N. H. Matlis, B. H. Shaw, E. Esarey and W. P. Leemans

Observing the Rosensweig instability of a quantum ferrofluid pp. 194-197

Holger Kadau, Matthias Schmitt, Matthias Wenzel, Clarissa Wink, Thomas Maier, Igor Ferrier-Barbut and Tilman Pfau

Observation of polar vortices in oxide superlattices pp. 198-201

A. K. Yadav, C. T. Nelson, S. L. Hsu, Z. Hong, J. D. Clarkson, C. M. Schlepütz, A. R. Damodaran, P. Shafer, E. Arenholz, L. R. Dedon, D. Chen, A. Vishwanath, A. M. Minor, L. Q. Chen, J. F. Scott, L. W. Martin and R. Ramesh

Macromolecular diffractive imaging using imperfect crystals pp. 202-206

Kartik Ayyer, Oleksandr M. Yefanov, Dominik Oberthür, Shatabdi Roy-Chowdhury, Lorenzo Galli, Valerio Mariani, Shibom Basu, Jesse Coe, Chelsie E. Conrad, Raimund Fromme, Alexander Schaffer, Katerina Dörner, Daniel James, Christopher Kupitz, Markus Metz, Garrett Nelson, Paulraj Lourdu Xavier, Kenneth R. Beyerlein, Marius Schmidt, Iosifina Sarrou, John C. H. Spence, Uwe Weierstall, Thomas A. White, Jay-How Yang, Yun Zhao, Mengning Liang, Andrew Aquila, Mark S. Hunter, Joseph S. Robinson, Jason E. Koglin, Sébastien Boutet, Petra Fromme, Anton Barty and Henry N. Chapman

Covariation of deep Southern Ocean oxygenation and atmospheric CO2 through the last ice age pp. 207-210

Samuel L. Jaccard, Eric D. Galbraith, Alfredo Martínez-García and Robert F. Anderson

Biomass resilience of Neotropical secondary forests pp. 211-214

Lourens Poorter, Frans Bongers, T. Mitchell Aide, Angélica M. Almeyda Zambrano, Patricia Balvanera, Justin M. Becknell, Vanessa Boukili, Pedro H. S. Brancalion, Eben N. Broadbent, Robin L. Chazdon, Dylan Craven, Jarcilene S. de Almeida-Cortez, George A. L. Cabral, Ben H. J. de Jong, Julie S. Denslow, Daisy H. Dent, Saara J. DeWalt, Juan M. Dupuy, Sandra M. Durán, Mario M. Espírito-Santo, María C. Fandino, Ricardo G. César, Jefferson S. Hall, José Luis Hernandez-Stefanoni, Catarina C. Jakovac, André B. Junqueira, Deborah Kennard, Susan G. Letcher, Juan-Carlos Licona, Madelon Lohbeck, Erika Marín-Spiotta, Miguel Martínez-Ramos, Paulo Massoca, Jorge A. Meave, Rita Mesquita, Francisco Mora, Rodrigo Muñoz, Robert Muscarella, Yule R. F. Nunes, Susana Ochoa-Gaona, Alexandre A. de Oliveira, Edith Orihuela-Belmonte, Marielos Peña-Claros, Eduardo A. Pérez-García, Daniel Piotto, Jennifer S. Powers, Jorge Rodríguez-Velázquez, I. Eunice Romero-Pérez, Jorge Ruíz, Juan G. Saldarriaga, Arturo Sanchez-Azofeifa, Naomi B. Schwartz, Marc K. Steininger, Nathan G. Swenson, Marisol Toledo, Maria Uriarte, Michiel van Breugel, Hans van der Wal, Maria D. M. Veloso, Hans F. M. Vester, Alberto Vicentini, Ima C. G. Vieira, Tony Vizcarra Bentos, G. Bruce Williamson and Danaë M. A. Rozendaal

New geological and palaeontological age constraint for the gorilla–human lineage split pp. 215-218

Shigehiro Katoh, Yonas Beyene, Tetsumaru Itaya, Hironobu Hyodo, Masayuki Hyodo, Koshi Yagi, Chitaro Gouzu, Giday WoldeGabriel, William K. Hart, Stanley H. Ambrose, Hideo Nakaya, Raymond L. Bernor, Jean-Renaud Boisserie, Faysal Bibi, Haruo Saegusa, Tomohiko Sasaki, Katsuhiro Sano, Berhane Asfaw and Gen Suwa

A thalamic input to the nucleus accumbens mediates opiate dependence pp. 219-222

Yingjie Zhu, Carl F. R. Wienecke, Gregory Nachtrab and Xiaoke Chen

Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche pp. 223-227

James Y. Chen, Masanori Miyanishi, Sean K. Wang, Satoshi Yamazaki, Rahul Sinha, Kevin S. Kao, Jun Seita, Debashis Sahoo, Hiromitsu Nakauchi and Irving L. Weissman

Real-time, portable genome sequencing for Ebola surveillance pp. 228-232

Joshua Quick, Nicholas J. Loman, Sophie Duraffour, Jared T. Simpson, Ettore Severi, Lauren Cowley, Joseph Akoi Bore, Raymond Koundouno, Gytis Dudas, Amy Mikhail, Nobila Ouédraogo, Babak Afrough, Amadou Bah, Jonathan H. J. Baum, Beate Becker-Ziaja, Jan Peter Boettcher, Mar Cabeza-Cabrerizo, Álvaro Camino-Sánchez, Lisa L. Carter, Juliane Doerrbecker, Theresa Enkirch, Isabel García- Dorival, Nicole Hetzelt, Julia Hinzmann, Tobias Holm, Liana Eleni Kafetzopoulou, Michel Koropogui, Abigael Kosgey, Eeva Kuisma, Christopher H. Logue, Antonio Mazzarelli, Sarah Meisel, Marc Mertens, Janine Michel, Didier Ngabo, Katja Nitzsche, Elisa Pallasch, Livia Victoria Patrono, Jasmine Portmann, Johanna Gabriella Repits, Natasha Y. Rickett, Andreas Sachse, Katrin Singethan, Inês Vitoriano, Rahel L. Yemanaberhan, Elsa G. Zekeng, Trina Racine, Alexander Bello, Amadou Alpha Sall, Ousmane Faye, Oumar Faye, N’Faly Magassouba, Cecelia V. Williams, Victoria Amburgey, Linda Winona, Emily Davis, Jon Gerlach, Frank Washington, Vanessa Monteil, Marine Jourdain, Marion Bererd, Alimou Camara, Hermann Somlare, Abdoulaye Camara, Marianne Gerard, Guillaume Bado, Bernard Baillet, Déborah Delaune, Koumpingnin Yacouba Nebie, Abdoulaye Diarra, Yacouba Savane, Raymond Bernard Pallawo, Giovanna Jaramillo Gutierrez, Natacha Milhano, Isabelle Roger, Christopher J. Williams, Facinet Yattara, Kuiama Lewandowski, James Taylor, Phillip Rachwal, Daniel J. Turner, Georgios Pollakis, Julian A. Hiscox, David A. Matthews, Matthew K. O’ Shea, Andrew McD. Johnston, Duncan Wilson, Emma Hutley, Erasmus Smit, Antonino Di Caro, Roman Wölfel, Kilian Stoecker, Erna Fleischmann, Martin Gabriel, Simon A. Weller, Lamine Koivogui, Boubacar Diallo, Sakoba Keïta, Andrew Rambaut, Pierre Formenty, Stephan Günther and Miles W. Carroll

Structure- and function-based design of Plasmodium-selective proteasome inhibitors pp. 233-236

Hao Li, Anthony J. O’Donoghue, Wouter A. van der Linden, Stanley C. Xie, Euna Yoo, Ian T. Foe, Leann Tilley, Charles S. Craik, Paula C. A. da Fonseca and Matthew Bogyo

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor pp. 237-241

Shin Isogai, Xavier Deupi, Christian Opitz, Franziska M. Heydenreich, Ching-Ju Tsai, Florian Brueckner, Gebhard F. X. Schertler, Dmitry B. Veprintsev and Stephan Grzesiek

Correction: Corrigendum: The ‘obligate diploid’ Candida albicans forms mating-competent haploids pp. 242-242

Meleah A. Hickman, Guisheng Zeng, Anja Forche, Matthew P. Hirakawa, Darren Abbey, Benjamin D. Harrison, Yan-Ming Wang, Ching-hua Su, Richard J. Bennett, Yue Wang and Judith Berman

Correction: Corrigendum: Human body epigenome maps reveal noncanonical DNA methylation variation pp. 242-242

Matthew D. Schultz, Yupeng He, John W. Whitaker, Manoj Hariharan, Eran A. Mukamel, Danny Leung, Nisha Rajagopal, Joseph R. Nery, Mark A. Urich, Huaming Chen, Shin Lin, Yiing Lin, Inkyung Jung, Anthony D. Schmitt, Siddarth Selvaraj, Bing Ren, Terrence J. Sejnowski, Wei Wang and Joseph R. Ecker

Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder pp. 242-242

Jerome Mertens, Qiu-Wen Wang, Yongsung Kim, Diana X. Yu, Son Pham, Bo Yang, Yi Zheng, Kenneth E. Diffenderfer, Jian Zhang, Sheila Soltani, Tameji Eames, Simon T. Schafer, Leah Boyer, Maria C. Marchetto, John I. Nurnberger, Joseph R. Calabrese, Ketil J. Oedegaard, Michael J. McCarthy, Peter P. Zandi, Martin Alda, Caroline M. Nievergelt, Shuangli Mi, Kristen J. Brennand, John R. Kelsoe, Fred H. Gage and Jun Yao

A bridge to business pp. 243-245

Peter Fiske

Turning point: Diversity ruling pp. 245-245

Virginia Gewin

The man with the spider pp. 248-248

Mohamad Atif Slim

2016, volume 530, articles 7588

Make journals report clinical trials properly pp. 7-7

Ben Goldacre

Zika virus: Brazil's surge in small-headed babies questioned by report pp. 13-14

Declan Butler

Academics across Europe join ‘Brexit’ debate pp. 15-15

Daniel Cressey

University seeks private donations to offset climate funding crunch pp. 16-17

Jeff Tollefson

Drugmakers target depression’s cognitive fog pp. 17-17

Heidi Ledford

Germany’s science hubs win in major research revamp pp. 18-19

Quirin Schiermeier

UK scientists gain licence to edit genes in human embryos pp. 18-18

Ewen Callaway

The mystery of the expanding tropics pp. 20-22

Olive Heffernan

Meet the soft, cuddly robots of the future pp. 24-26

Helen Shen

Reproducibility: A tragedy of errors pp. 27-29

David B. Allison, Andrew W. Brown, Brandon J. George and Kathryn A. Kaiser

Imaging: Medical modernist pp. 30-31

Thomas Schnalke

Books in brief pp. 31-31

Barbara Kiser

Architecture: The Crick Institute unpeeled pp. 32-32

Ewen Callaway

Mauritius culls threatened fruit bats pp. 33-33

F. B. Vincent Florens

Edited plants should not be patented pp. 33-33

John R. Porter, Jean-Louis Durand and Taline Elmayan

Tibetan wildlife hemmed in pp. 33-33

Weihong Ji, Achyut Aryal and Junhu Su

Balance research funds across Europe pp. 33-33

Giorgio Parisi

A toast to the deep-drilling idea pp. 33-33

Frank B. Estabrook

Photocatalysts in close-up pp. 36-37

Johan Hofkens and Maarten B. J. Roeffaers

A stretch in time pp. 37-38

Zachary Pincus

Disorder in the court pp. 38-39

T. Reid Alderson and Ad Bax

Ultrashort light pulses shake atoms pp. 41-42

Kyung Taec Kim

Fibroblasts for all seasons pp. 42-43

Erwin F. Wagner

A home for Xenoturbella pp. 43-43

Henry Gee

Structural disorder of monomeric α-synuclein persists in mammalian cells pp. 45-50

Francois-Xavier Theillet, Andres Binolfi, Beata Bekei, Andrea Martorana, Honor May Rose, Marchel Stuiver, Silvia Verzini, Dorothea Lorenz, Marleen van Rossum, Daniella Goldfarb and Philipp Selenko

Persistent HIV-1 replication maintains the tissue reservoir during therapy pp. 51-56

Ramon Lorenzo-Redondo, Helen R. Fryer, Trevor Bedford, Eun-Young Kim, John Archer, Sergei L. Kosakovsky Pond, Yoon-Seok Chung, Sudhir Penugonda, Jeffrey G. Chipman, Courtney V. Fletcher, Timothy W. Schacker, Michael H. Malim, Andrew Rambaut, Ashley T. Haase, Angela R. McLean and Steven M. Wolinsky

Active medulloblastoma enhancers reveal subgroup-specific cellular origins pp. 57-62

Charles Y. Lin, Serap Erkek, Yiai Tong, Linlin Yin, Alexander J. Federation, Marc Zapatka, Parthiv Haldipur, Daisuke Kawauchi, Thomas Risch, Hans-Jörg Warnatz, Barbara C. Worst, Bensheng Ju, Brent A. Orr, Rhamy Zeid, Donald R. Polaski, Maia Segura-Wang, Sebastian M. Waszak, David T. W. Jones, Marcel Kool, Volker Hovestadt, Ivo Buchhalter, Laura Sieber, Pascal Johann, Lukas Chavez, Stefan Gröschel, Marina Ryzhova, Andrey Korshunov, Wenbiao Chen, Victor V. Chizhikov, Kathleen J. Millen, Vyacheslav Amstislavskiy, Hans Lehrach, Marie-Laure Yaspo, Roland Eils, Peter Lichter, Jan O. Korbel, Stefan M. Pfister, James E. Bradner and Paul A. Northcott

A homogeneous nucleus for comet 67P/Churyumov–Gerasimenko from its gravity field pp. 63-65

M. Pätzold, T. Andert, M. Hahn, S. W. Asmar, J.-P. Barriot, M. K. Bird, B. Häusler, K. Peter, S. Tellmann, E. Grün, P. R. Weissman, H. Sierks, L. Jorda, R. Gaskell, F. Preusker and F. Scholten

Optical attosecond pulses and tracking the nonlinear response of bound electrons pp. 66-70

M. Th. Hassan, T. T. Luu, A. Moulet, O. Raskazovskaya, P. Zhokhov, M. Garg, N. Karpowicz, A. M. Zheltikov, V. Pervak, F. Krausz and E. Goulielmakis

Bioresorbable silicon electronic sensors for the brain pp. 71-76

Seung-Kyun Kang, Rory K. J. Murphy, Suk-Won Hwang, Seung Min Lee, Daniel V. Harburg, Neil A. Krueger, Jiho Shin, Paul Gamble, Huanyu Cheng, Sooyoun Yu, Zhuangjian Liu, Jordan G. McCall, Manu Stephen, Hanze Ying, Jeonghyun Kim, Gayoung Park, R. Chad Webb, Chi Hwan Lee, Sangjin Chung, Dae Seung Wie, Amit D. Gujar, Bharat Vemulapalli, Albert H. Kim, Kyung-Mi Lee, Jianjun Cheng, Younggang Huang, Sang Hoon Lee, Paul V. Braun, Wilson Z. Ray and John A. Rogers

Sub-particle reaction and photocurrent mapping to optimize catalyst-modified photoanodes pp. 77-80

Justin B. Sambur, Tai-Yen Chen, Eric Choudhary, Guanqun Chen, Erin J. Nissen, Elayne M. Thomas, Ningmu Zou and Peng Chen

Dehydration of lawsonite could directly trigger earthquakes in subducting oceanic crust pp. 81-84

Keishi Okazaki and Greg Hirth

Historical nectar assessment reveals the fall and rise of floral resources in Britain pp. 85-88

Mathilde Baude, William E. Kunin, Nigel D. Boatman, Simon Conyers, Nancy Davies, Mark A. K. Gillespie, R. Daniel Morton, Simon M. Smart and Jane Memmott

Xenacoelomorpha is the sister group to Nephrozoa pp. 89-93

Johanna Taylor Cannon, Bruno Cossermelli Vellutini, Julian Smith, Fredrik Ronquist, Ulf Jondelius and Andreas Hejnol

New deep-sea species of Xenoturbella and the position of Xenacoelomorpha pp. 94-97

Greg W. Rouse, Nerida G. Wilson, Jose I. Carvajal and Robert C. Vrijenhoek

Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2 pp. 98-102

Zhen Liu, Xiao Li, Jun-Tao Zhang, Yi-Jun Cai, Tian-Lin Cheng, Cheng Cheng, Yan Wang, Chen-Chen Zhang, Yan-Hong Nie, Zhi-Fang Chen, Wen-Jie Bian, Ling Zhang, Jianqiu Xiao, Bin Lu, Yue-Fang Zhang, Xiao-Di Zhang, Xiao Sang, Jia-Jia Wu, Xiu Xu, Zhi-Qi Xiong, Feng Zhang, Xiang Yu, Neng Gong, Wen-Hao Zhou, Qiang Sun and Zilong Qiu

The temporal scaling of Caenorhabditis elegans ageing pp. 103-107

Nicholas Stroustrup, Winston E. Anthony, Zachary M. Nash, Vivek Gowda, Adam Gomez, Isaac F. López-Moyado, Javier Apfeld and Walter Fontana

An essential receptor for adeno-associated virus infection pp. 108-112

S. Pillay, N. L. Meyer, A. S. Puschnik, O. Davulcu, J. Diep, Y. Ishikawa, L. T. Jae, J. E. Wosen, C. M. Nagamine, M. S. Chapman and J. E. Carette

Genome-wide nucleosome specificity and function of chromatin remodellers in ES cells pp. 113-116

Maud de Dieuleveult, Kuangyu Yen, Isabelle Hmitou, Arnaud Depaux, Fayçal Boussouar, Daria Bou Dargham, Sylvie Jounier, Hélène Humbertclaude, Florence Ribierre, Céline Baulard, Nina P. Farrell, Bongsoo Park, Céline Keime, Lucie Carrière, Soizick Berlivet, Marta Gut, Ivo Gut, Michel Werner, Jean-François Deleuze, Robert Olaso, Jean-Christophe Aude, Sophie Chantalat, B. Franklin Pugh and Matthieu Gérard

Open journals that piggyback on arXiv gather momentum pp. 117-118

Elizabeth Gibney

The code librarian pp. 118-118

Jeffrey Perkel

Counselling: Knowledge is power pp. 119-120

Paul Smaglik

The question I hate the most pp. 121-121

Eleftherios P. Diamandis

Trade talk: Neuro connector pp. 121-121

Monya Baker

Musings on time travel pp. 124-124

Robert Reed