Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours

J. Justin Milner, Clara Toma, Bingfei Yu, Kai Zhang, Kyla Omilusik, Anthony T. Phan, Dapeng Wang, Adam J. Getzler, Toan Nguyen, Shane Crotty, Wei Wang, Matthew E. Pipkin () and Ananda W. Goldrath ()
Additional contact information
J. Justin Milner: University of California, San Diego
Clara Toma: University of California, San Diego
Bingfei Yu: University of California, San Diego
Kai Zhang: Bioinformatics and Systems Biology Graduate Program, University of California, San Diego
Kyla Omilusik: University of California, San Diego
Anthony T. Phan: University of California, San Diego
Dapeng Wang: The Scripps Research Institute
Adam J. Getzler: The Scripps Research Institute
Toan Nguyen: University of California, San Diego
Shane Crotty: La Jolla Institute for Allergy and Immunology
Wei Wang: Bioinformatics and Systems Biology Graduate Program, University of California, San Diego
Matthew E. Pipkin: The Scripps Research Institute
Ananda W. Goldrath: University of California, San Diego

Nature, 2017, vol. 552, issue 7684, 253-257

Abstract: The transcription factor Runx3 is identified as a central regulator of the development of tissue-resident memory CD8+ T cells, providing insights into the signals that promote T cell residency in non-lymphoid tissues and tumours.

Date: 2017
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DOI: 10.1038/nature24993

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