Programmable self-assembly of three-dimensional nanostructures from 10,000 unique components

Luvena L. Ong, Nikita Hanikel, Omar K. Yaghi, Casey Grun, Maximilian T. Strauss, Patrick Bron, Josephine Lai-Kee-Him, Florian Schueder, Bei Wang, Pengfei Wang, Jocelyn Y. Kishi, Cameron Myhrvold, Allen Zhu, Ralf Jungmann, Gaetan Bellot (), Yonggang Ke () and Peng Yin ()
Additional contact information
Luvena L. Ong: Wyss Institute for Biologically Inspired Engineering, Harvard University
Nikita Hanikel: Wyss Institute for Biologically Inspired Engineering, Harvard University
Omar K. Yaghi: Wyss Institute for Biologically Inspired Engineering, Harvard University
Casey Grun: Wyss Institute for Biologically Inspired Engineering, Harvard University
Maximilian T. Strauss: Wyss Institute for Biologically Inspired Engineering, Harvard University
Patrick Bron: Centre de Biochimie Structurale, CNRS UMR 5048, INSERM U1054
Josephine Lai-Kee-Him: Centre de Biochimie Structurale, CNRS UMR 5048, INSERM U1054
Florian Schueder: Wyss Institute for Biologically Inspired Engineering, Harvard University
Bei Wang: Wyss Institute for Biologically Inspired Engineering, Harvard University
Pengfei Wang: Emory University and Georgia Institute of Technology
Jocelyn Y. Kishi: Wyss Institute for Biologically Inspired Engineering, Harvard University
Cameron Myhrvold: Wyss Institute for Biologically Inspired Engineering, Harvard University
Allen Zhu: Wyss Institute for Biologically Inspired Engineering, Harvard University
Ralf Jungmann: Max Planck Institute of Biochemistry
Gaetan Bellot: Institut de Génomique Fonctionnelle, CNRS UMR 5203, INSERM U1191
Yonggang Ke: Emory University and Georgia Institute of Technology
Peng Yin: Wyss Institute for Biologically Inspired Engineering, Harvard University

Nature, 2017, vol. 552, issue 7683, 72-77

Abstract: DNA bricks with binding domains of 13 nucleotides instead of the typical 8 make it possible to self-assemble gigadalton-scale, three-dimensional nanostructures consisting of tens of thousands of unique components.

Date: 2017
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DOI: 10.1038/nature24648

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