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2012, volume 486, articles 7404

No inter-hemispheric δ13CH4 trend observed pp. E3-E4

I. Levin, C. Veidt, B. H. Vaughn, G. Brailsford, T. Bromley, R. Heinz, D. Lowe, J. B. Miller, C. Poß and J. W. C. White

Kai, Tyler, Randerson & Blake reply pp. E4-E4

Fuu Ming Kai, Stanley C. Tyler, James T. Randerson and Donald R. Blake

Open your minds and share your results pp. 441-441

Geoffrey Boulton

Wealth gap curbs Rio goals pp. 447-447

Jeff Tollefson

Freeze on mutant-flu research set to thaw pp. 449-450

Declan Butler

Sea versus senators pp. 450-450

Leigh Phillips

California condors face lead menace pp. 451-451

Meera Subramanian

Science at stake in Mexican election pp. 452-452

Erik Vance

Model pigs face messy path pp. 453-453

Amy Maxmen

Fetal tests spur legal battle pp. 454-454

Erika Check Hayden

Influenza: Five questions on H5N1 pp. 456-458

Ed Yong

Phylogeny: Rewriting evolution pp. 460-462

Elie Dolgin

Save the Baltic Sea pp. 463-464

Daniel J. Conley

Get pigs off antibiotics pp. 465-466

Frank Aarestrup

Physics: A shining life pp. 468-469

Frank Close

Cities: Metropolitan mash-up pp. 470-470

Anthony King

Fiction: Ray Bradbury, an appreciation pp. 471-471

David Brin

Q&A: The sound catcher pp. 472-472

Jascha Hoffman

Carson no 'beacon of reason' on DDT pp. 473-473

Tony Trewavas

Help to survey the use of smart drugs pp. 473-473

Imre Bard and Ilina Singh

Less lactation may explain cancer rise pp. 473-473

Anne Marie Oudesluys-Murphy

Limit consumption to preserve habitats pp. 473-473

Marco Sakai

Clue to an ancient cosmic-ray event? pp. 473-473

Jonathon Allen

Andrew Fielding Huxley (1917–2012) pp. 474-474

Yale E. Goldman, Clara Franzini-Armstrong and Clay M. Armstrong

Swirls in the corona pp. 476-477

Stephen J. Bradshaw

A healthy diet for stem cells pp. 477-478

Fresnida J. Ramos and Matt Kaeberlein

Directors extend their reach pp. 478-479

Matthew O. Kitching and Victor Snieckus

A false sense of non-self pp. 479-481

Ellis L. Reinherz

Genes and human brain evolution pp. 481-482

Daniel H. Geschwind and Genevieve Konopka

Pinprick diagnostics pp. 482-483

Eduardo Vilar and Josep Tabernero

Dimensionality of consumer search space drives trophic interaction strengths pp. 485-489

Samraat Pawar, Anthony I. Dell and Savage Van M.

mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake pp. 490-495

Ömer H. Yilmaz, Pekka Katajisto, Dudley W. Lamming, Yetis Gültekin, Khristian E. Bauer-Rowe, Shomit Sengupta, Kivanc Birsoy, Abdulmetin Dursun, V. Onur Yilmaz, Martin Selig, G. Petur Nielsen, Mari Mino-Kenudson, Lawrence R. Zukerberg, Atul K. Bhan, Vikram Deshpande and David M. Sabatini

A map of nucleosome positions in yeast at base-pair resolution pp. 496-501

Kristin Brogaard, Liqun Xi, Ji-Ping Wang and Jonathan Widom

The signature of orbital motion from the dayside of the planet τ Boötis b pp. 502-504

Matteo Brogi, Ignas A. G. Snellen, Remco J. de Kok, Simon Albrecht, Jayne Birkby and Ernst J. W. de Mooij

Magnetic tornadoes as energy channels into the solar corona pp. 505-508

Sven Wedemeyer-Böhm, Eamon Scullion, Oskar Steiner, Luc Rouppe van der Voort, Jaime de la Cruz Rodriguez, Viktor Fedun and Robert Erdélyi

The limits of the nuclear landscape pp. 509-512

Jochen Erler, Noah Birge, Markus Kortelainen, Witold Nazarewicz, Erik Olsen, Alexander M. Perhac and Mario Stoitsov

Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight pp. 513-517

N. D. Loh, C. Y. Hampton, A. V. Martin, D. Starodub, R. G. Sierra, A. Barty, A. Aquila, J. Schulz, L. Lomb, J. Steinbrener, R. L. Shoeman, S. Kassemeyer, C. Bostedt, J. Bozek, S. W. Epp, B. Erk, R. Hartmann, D. Rolles, A. Rudenko, B. Rudek, L. Foucar, N. Kimmel, G. Weidenspointner, G. Hauser, P. Holl, E. Pedersoli, M. Liang, M. S. Hunter, L. Gumprecht, N. Coppola, C. Wunderer, H. Graafsma, F. R. N. C. Maia, T. Ekeberg, M. Hantke, H. Fleckenstein, H. Hirsemann, K. Nass, T. A. White, H. J. Tobias, G. R. Farquar, W. H. Benner, S. P. Hau-Riege, C. Reich, A. Hartmann, H. Soltau, S. Marchesini, S. Bajt, M. Barthelmess, P. Bucksbaum, K. O. Hodgson, L. Strüder, J. Ullrich, M. Frank, I. Schlichting, H. N. Chapman and M. J. Bogan

Activation of remote meta-C–H bonds assisted by an end-on template pp. 518-522

Dasheng Leow, Gang Li, Tian-Sheng Mei and Jin-Quan Yu

Three-dimensional limb joint mobility in the early tetrapod Ichthyostega pp. 523-526

Stephanie E. Pierce, Jennifer A. Clack and John R. Hutchinson

The bonobo genome compared with the chimpanzee and human genomes pp. 527-531

Kay Prüfer, Kasper Munch, Ines Hellmann, Keiko Akagi, Jason R. Miller, Brian Walenz, Sergey Koren, Granger Sutton, Chinnappa Kodira, Roger Winer, James R. Knight, James C. Mullikin, Stephen J. Meader, Chris P. Ponting, Gerton Lunter, Saneyuki Higashino, Asger Hobolth, Julien Dutheil, Emre Karakoç, Can Alkan, Saba Sajjadian, Claudia Rita Catacchio, Mario Ventura, Tomas Marques-Bonet, Evan E. Eichler, Claudine André, Rebeca Atencia, Lawrence Mugisha, Jörg Junhold, Nick Patterson, Michael Siebauer, Jeffrey M. Good, Anne Fischer, Susan E. Ptak, Michael Lachmann, David E. Symer, Thomas Mailund, Mikkel H. Schierup, Aida M. Andrés, Janet Kelso and Svante Pääbo

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer pp. 532-536

Sandra Misale, Rona Yaeger, Sebastijan Hobor, Elisa Scala, Manickam Janakiraman, David Liska, Emanuele Valtorta, Roberta Schiavo, Michela Buscarino, Giulia Siravegna, Katia Bencardino, Andrea Cercek, Chin-Tung Chen, Silvio Veronese, Carlo Zanon, Andrea Sartore-Bianchi, Marcello Gambacorta, Margherita Gallicchio, Efsevia Vakiani, Valentina Boscaro, Enzo Medico, Martin Weiser, Salvatore Siena, Federica Di Nicolantonio, David Solit and Alberto Bardelli

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers pp. 537-540

Luis A. Diaz, Richard T. Williams, Jian Wu, Isaac Kinde, J. Randolph Hecht, Jordan Berlin, Benjamin Allen, Ivana Bozic, Johannes G. Reiter, Martin A. Nowak, Kenneth W. Kinzler, Kelly S. Oliner and Bert Vogelstein

Autoregulation of microRNA biogenesis by let-7 and Argonaute pp. 541-544

Dimitrios G. Zisoulis, Zoya S. Kai, Roger K. Chang and Amy E. Pasquinelli

Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells pp. 545-548

Tajie H. Harris, Edward J. Banigan, David A. Christian, Christoph Konradt, Elia D. Tait Wojno, Kazumi Norose, Emma H. Wilson, Beena John, Wolfgang Weninger, Andrew D. Luster, Andrea J. Liu and Christopher A. Hunter

PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells pp. 549-553

Daniela Cipolletta, Markus Feuerer, Amy Li, Nozomu Kamei, Jongsoon Lee, Steven E. Shoelson, Christophe Benoist and Diane Mathis

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire pp. 554-558

Patricia T. Illing, Julian P. Vivian, Nadine L. Dudek, Lyudmila Kostenko, Zhenjun Chen, Mandvi Bharadwaj, John J. Miles, Lars Kjer-Nielsen, Stephanie Gras, Nicholas A. Williamson, Scott R. Burrows, Anthony W. Purcell, Jamie Rossjohn and James McCluskey

Grant applications: Find me the money pp. 559-561

Lucas Laursen

Celestial bodies pp. 564-564

Ken Liu

2012, volume 486, articles 7403

Rest et al. reply pp. E1-E2

A. Rest, J. L. Prieto, N. R. Walborn, N. Smith, F. B. Bianco, R. Chornock, D. L. Welch, D. A. Howell, M. E. Huber, R. J. Foley, W. Fong, B. Sinnott, H. E. Bond, R. C. Smith, I. Toledo, D. Minniti and K. Mandel

Editorial: Taste pp. S1-S1

Herb Brody

The Great Eruption of η Carinae pp. E1-E1

Kris Davidson and Roberta M. Humphreys

Gustatory system: The finer points of taste pp. S2-S3

Bijal P. Trivedi

Sensory science: Partners in flavour pp. S4-S5

Nicholas Bakalar

Perspective: Complexities of flavour pp. S6-S6

Barry Smith

Neuroscience: Hardwired for taste pp. S7-S9

Bijal P. Trivedi

Cooking: Delicious science pp. S10-S11

Courtney Humphries

Obesity: Insensitive issue pp. S12-S13

James Mitchell Crow

Food science: Taste bud hackers pp. S14-S15

Lauren Gravitz

Evolutionary biology: The lost appetites pp. S16-S17

Ewen Callaway

Technology: The taste of things to come pp. S18-S19

Neil Savage

Do not censor science in the name of biosecurity pp. 295-295

Tim Trevan

Nobel fight over African HIV centre pp. 301-302

Declan Butler

Britain aims for broad open access pp. 302-303

Richard Van Noorden

A workforce out of balance pp. 304-304

Meredith Wadman

Romanian prime minister accused of plagiarism pp. 305-305

Quirin Schiermeier

Peru battles the golden curse of Madre de Dios pp. 306-307

Elie Gardner

Cuts leave Greek heritage in ruins pp. 308-308

Leigh Phillips

The trouble with turbines: An ill wind pp. 310-311

Meera Subramanian

Informed consent: A broken contract pp. 312-314

Erika Check Hayden

Aspen physics turns 50 pp. 315-317

Michael S. Turner

Nobel Prize: A dark edge to the glory pp. 318-319

Hidde Ploegh

Animal behaviour: Dissecting decay pp. 320-320

Clive Wynne

Mathematics: A life computed pp. 321-321

James Poskett

More ways to govern geoengineering pp. 323-323

Jane C. S. Long, Steve Hamburg and John Shepherd

Use fast reactors to burn plutonium pp. 323-323

Barry W. Brook, Tom Blees and William H. Hannum

Spread the risk of antibiotic research pp. 323-323

Chris Schofield

Monitor sea pollution to stop strandings pp. 323-323

Juan Jose Alava

China must provide education on HIV pp. 323-323

Jian Zhang and Nan Jiang

Akira Tonomura (1942–2012) pp. 324-324

Archie Howie

Computer model predicts side effects pp. 326-327

Kyle Kolaja

Carbon origami pp. 327-328

Jay S. Siegel

The breast cancer landscape pp. 328-329

Joe Gray and Brian Druker

Symmetrical tin pp. 330-331

Daniel Bazin

Early start for rocky planets pp. 331-332

Debra Fischer

Bird flu in mammals pp. 332-333

Hui-Ling Yen and Joseph Sriyal Malik Peiris

Engineering H5N1 avian influenza viruses to study human adaptation pp. 335-340

David M. Morens, Kanta Subbarao and Jeffery K. Taubenberger

Superallowed Gamow–Teller decay of the doubly magic nucleus 100Sn pp. 341-345

C. B. Hinke, M. Böhmer, P. Boutachkov, T. Faestermann, H. Geissel, J. Gerl, R. Gernhäuser, M. Górska, A. Gottardo, H. Grawe, J. L. Grębosz, R. Krücken, N. Kurz, Z. Liu, L. Maier, F. Nowacki, S. Pietri, Zs. Podolyák, K. Sieja, K. Steiger, K. Straub, H. Weick, H.-J. Wollersheim, P. J. Woods, N. Al-Dahan, N. Alkhomashi, A. Ataç, A. Blazhev, N. F. Braun, I. T. Čeliković, T. Davinson, I. Dillmann, C. Domingo-Pardo, P. C. Doornenbal, G. de France, G. F. Farrelly, F. Farinon, N. Goel, T. C. Habermann, R. Hoischen, R. Janik, M. Karny, A. Kaşkaş, I. M. Kojouharov, Th. Kröll, Y. Litvinov, S. Myalski, F. Nebel, S. Nishimura, C. Nociforo, J. Nyberg, A. R. Parikh, A. Procházka, P. H. Regan, C. Rigollet, H. Schaffner, C. Scheidenberger, S. Schwertel, P.-A. Söderström, S. J. Steer, A. Stolz and P. Strmeň

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups pp. 346-352

Christina Curtis, Sohrab P. Shah, Suet-Feung Chin, Gulisa Turashvili, Oscar M. Rueda, Mark J. Dunning, Doug Speed, Andy G. Lynch, Shamith Samarajiwa, Yinyin Yuan, Stefan Gräf, Gavin Ha, Gholamreza Haffari, Ali Bashashati, Roslin Russell, Steven McKinney, Anita Langerød, Andrew Green, Elena Provenzano, Gordon Wishart, Sarah Pinder, Peter Watson, Florian Markowetz, Leigh Murphy, Ian Ellis, Arnie Purushotham, Anne-Lise Børresen-Dale, James D. Brenton, Simon Tavaré, Carlos Caldas and Samuel Aparicio

Whole-genome analysis informs breast cancer response to aromatase inhibition pp. 353-360

Matthew J. Ellis, Li Ding, Dong Shen, Jingqin Luo, Vera J. Suman, John W. Wallis, Brian A. Van Tine, Jeremy Hoog, Reece J. Goiffon, Theodore C. Goldstein, Sam Ng, Li Lin, Robert Crowder, Jacqueline Snider, Karla Ballman, Jason Weber, Ken Chen, Daniel C. Koboldt, Cyriac Kandoth, William S. Schierding, Joshua F. McMichael, Christopher A. Miller, Charles Lu, Christopher C. Harris, Michael D. McLellan, Michael C. Wendl, Katherine DeSchryver, D. Craig Allred, Laura Esserman, Gary Unzeitig, Julie Margenthaler, G. V. Babiera, P. Kelly Marcom, J. M. Guenther, Marilyn Leitch, Kelly Hunt, John Olson, Yu Tao, Christopher A. Maher, Lucinda L. Fulton, Robert S. Fulton, Michelle Harrison, Ben Oberkfell, Feiyu Du, Ryan Demeter, Tammi L. Vickery, Adnan Elhammali, Helen Piwnica-Worms, Sandra McDonald, Mark Watson, David J. Dooling, David Ota, Li-Wei Chang, Ron Bose, Timothy J. Ley, David Piwnica-Worms, Joshua M. Stuart, Richard K. Wilson and Elaine R. Mardis

Large-scale prediction and testing of drug activity on side-effect targets pp. 361-367

Eugen Lounkine, Michael J. Keiser, Steven Whitebread, Dmitri Mikhailov, Jacques Hamon, Jeremy L. Jenkins, Paul Lavan, Eckhard Weber, Allison K. Doak, Serge Côté, Brian K. Shoichet and Laszlo Urban

Structure of yeast Argonaute with guide RNA pp. 368-374

Kotaro Nakanishi, David E. Weinberg, David P. Bartel and Dinshaw J. Patel

An abundance of small exoplanets around stars with a wide range of metallicities pp. 375-377

Lars A. Buchhave, David W. Latham, Anders Johansen, Martin Bizzarro, Guillermo Torres, Jason F. Rowe, Natalie M. Batalha, William J. Borucki, Erik Brugamyer, Caroline Caldwell, Stephen T. Bryson, David R. Ciardi, William D. Cochran, Michael Endl, Gilbert A. Esquerdo, Eric B. Ford, John C. Geary, Ronald L. Gilliland, Terese Hansen, Howard Isaacson, John B. Laird, Philip W. Lucas, Geoffrey W. Marcy, Jon A. Morse, Paul Robertson, Avi Shporer, Robert P. Stefanik, Martin Still and Samuel N. Quinn

Constraints on the volatile distribution within Shackleton crater at the lunar south pole pp. 378-381

Maria T. Zuber, James W. Head, David E. Smith, Gregory A. Neumann, Erwan Mazarico, Mark H. Torrence, Oded Aharonson, Alexander R. Tye, Caleb I. Fassett, Margaret A. Rosenburg and H. Jay Melosh

Electronic nematicity above the structural and superconducting transition in BaFe2(As1−xP x )2 pp. 382-385

S. Kasahara, H. J. Shi, K. Hashimoto, S. Tonegawa, Y. Mizukami, T. Shibauchi, K. Sugimoto, T. Fukuda, T. Terashima, Andriy H. Nevidomskyy and Y. Matsuda

Multiscale gigapixel photography pp. 386-389

D. J. Brady, M. E. Gehm, R. A. Stack, D. L. Marks, D. S. Kittle, D. R. Golish, E. M. Vera and S. D. Feller

First dairying in green Saharan Africa in the fifth millennium bc pp. 390-394

Julie Dunne, Richard P. Evershed, Mélanie Salque, Lucy Cramp, Silvia Bruni, Kathleen Ryan, Stefano Biagetti and Savino di Lernia

The clonal and mutational evolution spectrum of primary triple-negative breast cancers pp. 395-399

Sohrab P. Shah, Andrew Roth, Rodrigo Goya, Arusha Oloumi, Gavin Ha, Yongjun Zhao, Gulisa Turashvili, Jiarui Ding, Kane Tse, Gholamreza Haffari, Ali Bashashati, Leah M. Prentice, Jaswinder Khattra, Angela Burleigh, Damian Yap, Virginie Bernard, Andrew McPherson, Karey Shumansky, Anamaria Crisan, Ryan Giuliany, Alireza Heravi-Moussavi, Jamie Rosner, Daniel Lai, Inanc Birol, Richard Varhol, Angela Tam, Noreen Dhalla, Thomas Zeng, Kevin Ma, Simon K. Chan, Malachi Griffith, Annie Moradian, S.-W. Grace Cheng, Gregg B. Morin, Peter Watson, Karen Gelmon, Stephen Chia, Suet-Feung Chin, Christina Curtis, Oscar M. Rueda, Paul D. Pharoah, Sambasivarao Damaraju, John Mackey, Kelly Hoon, Timothy Harkins, Vasisht Tadigotla, Mahvash Sigaroudinia, Philippe Gascard, Thea Tlsty, Joseph F. Costello, Irmtraud M. Meyer, Connie J. Eaves, Wyeth W. Wasserman, Steven Jones, David Huntsman, Martin Hirst, Carlos Caldas, Marco A. Marra and Samuel Aparicio

The landscape of cancer genes and mutational processes in breast cancer pp. 400-404

Philip J. Stephens, Patrick S. Tarpey, Helen Davies, Peter Van Loo, Chris Greenman, David C. Wedge, Serena Nik-Zainal, Sancha Martin, Ignacio Varela, Graham R. Bignell, Lucy R. Yates, Elli Papaemmanuil, David Beare, Adam Butler, Angela Cheverton, John Gamble, Jonathan Hinton, Mingming Jia, Alagu Jayakumar, David Jones, Calli Latimer, King Wai Lau, Stuart McLaren, David J. McBride, Andrew Menzies, Laura Mudie, Keiran Raine, Roland Rad, Michael Spencer Chapman, Jon Teague, Douglas Easton, Anita Langerød, Ming Ta Michael Lee, Chen-Yang Shen, Benita Tan Kiat Tee, Bernice Wong Huimin, Annegien Broeks, Ana Cristina Vargas, Gulisa Turashvili, John Martens, Aquila Fatima, Penelope Miron, Suet-Feung Chin, Gilles Thomas, Sandrine Boyault, Odette Mariani, Sunil R. Lakhani, Marc van de Vijver, Laura van ‘t Veer, John Foekens, Christine Desmedt, Christos Sotiriou, Andrew Tutt, Carlos Caldas, Jorge S. Reis-Filho, Samuel A. J. R. Aparicio, Anne Vincent Salomon, Anne-Lise Børresen-Dale, Andrea L. Richardson, Peter J. Campbell, P. Andrew Futreal and Michael R. Stratton

Sequence analysis of mutations and translocations across breast cancer subtypes pp. 405-409

Shantanu Banerji, Kristian Cibulskis, Claudia Rangel-Escareno, Kristin K. Brown, Scott L. Carter, Abbie M. Frederick, Michael S. Lawrence, Andrey Y. Sivachenko, Carrie Sougnez, Lihua Zou, Maria L. Cortes, Juan C. Fernandez-Lopez, Shouyong Peng, Kristin G. Ardlie, Daniel Auclair, Veronica Bautista-Piña, Fujiko Duke, Joshua Francis, Joonil Jung, Antonio Maffuz-Aziz, Robert C. Onofrio, Melissa Parkin, Nam H. Pho, Valeria Quintanar-Jurado, Alex H. Ramos, Rosa Rebollar-Vega, Sergio Rodriguez-Cuevas, Sandra L. Romero-Cordoba, Steven E. Schumacher, Nicolas Stransky, Kristin M. Thompson, Laura Uribe-Figueroa, Jose Baselga, Rameen Beroukhim, Kornelia Polyak, Dennis C. Sgroi, Andrea L. Richardson, Gerardo Jimenez-Sanchez, Eric S. Lander, Stacey B. Gabriel, Levi A. Garraway, Todd R. Golub, Jorge Melendez-Zajgla, Alex Toker, Gad Getz, Alfredo Hidalgo-Miranda and Matthew Meyerson

Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors pp. 410-414

Nicola J. Allen, Mariko L. Bennett, Lynette C. Foo, Gordon X. Wang, Chandrani Chakraborty, Stephen J. Smith and Ben A. Barres

PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos pp. 415-419

Toshinobu Nakamura, Yu-Jung Liu, Hiroyuki Nakashima, Hiroki Umehara, Kimiko Inoue, Shogo Matoba, Makoto Tachibana, Atsuo Ogura, Yoichi Shinkai and Toru Nakano

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets pp. 420-428

Masaki Imai, Tokiko Watanabe, Masato Hatta, Subash C. Das, Makoto Ozawa, Kyoko Shinya, Gongxun Zhong, Anthony Hanson, Hiroaki Katsura, Shinji Watanabe, Chengjun Li, Eiryo Kawakami, Shinya Yamada, Maki Kiso, Yasuo Suzuki, Eileen A. Maher, Gabriele Neumann and Yoshihiro Kawaoka

Life sciences: All jazzed up pp. 429-431

Amanda Mascarelli

Piled too high pp. 431-431

Mariano A. Loza-Coll

21st-century girl pp. 434-434

Adrian Tchaikovsky

2012, volume 486, articles 7402

Researchers can't regulate climate engineering alone pp. 159-159

Jason Blackstock

Poverty project opens to scrutiny pp. 165-166

Declan Butler

Journal offers flat fee for ‘all you can publish’ pp. 166-166

Richard Van Noorden

Genome test slammed for assessing ‘racial purity’ pp. 167-167

Alison Abbott

Stellar UK scope faces closure pp. 168-168

Eric Hand

Grant review opens up Texas-sized rift pp. 169-171

Meredith Wadman

Tabletop X-rays light up pp. 172-172

Katherine Bourzac

Metallic hydrogen: Hard pressed pp. 174-176

Ivan Amato

Neuroscience: The mind reader pp. 178-180

David Cyranoski

A midlife crisis for X-ray astronomy pp. 181-182

Martin Elvis

Climate models at their limit? pp. 183-184

Mark Maslin and Patrick Austin

Sanitation for all pp. 185-185

Sunita Narain

Q&A: Architect of change pp. 190-190

Anna Petherick

Don't forget health in sustainability talks pp. 191-191

Bianca Brijnath, Anthony J. McMichael and Colin D. Butler

US policy should not shape collaborations pp. 191-191

Bridget Pratt and Bebe Loff

Planetary boundaries concept is valuable pp. 191-191

Victor Galaz

Combat the effects of Forest Code changes pp. 191-191

Alison G. Nazareno

Learning about who we are pp. 194-195

David A. Relman

Majorana modes materialize pp. 195-196

Frank Wilczek

Reconstructing the third dimension pp. 197-198

Dilano Saldin

A life or death switch pp. 198-199

Andrea A. Gust and Thorsten Nürnberger

An infant giant pp. 199-200

Alberto D. Bolatto

Visualizing heavy fermions emerging in a quantum critical Kondo lattice pp. 201-206

Pegor Aynajian, Eduardo H. da Silva Neto, András Gyenis, Ryan E. Baumbach, J. D. Thompson, Zachary Fisk, Eric D. Bauer and Ali Yazdani

Human gut microbiome viewed across age and geography pp. 222-227

Tanya Yatsunenko, Federico E. Rey, Mark J. Manary, Indi Trehan, Maria Gloria Dominguez-Bello, Monica Contreras, Magda Magris, Glida Hidalgo, Robert N. Baldassano, Andrey P. Anokhin, Andrew C. Heath, Barbara Warner, Jens Reeder, Justin Kuczynski, J. Gregory Caporaso, Catherine A. Lozupone, Christian Lauber, Jose Carlos Clemente, Dan Knights, Rob Knight and Jeffrey I. Gordon

NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants pp. 228-232

Zheng Qing Fu, Shunping Yan, Abdelaty Saleh, Wei Wang, James Ruble, Nodoka Oka, Rajinikanth Mohan, Steven H. Spoel, Yasuomi Tada, Ning Zheng and Xinnian Dong

The intense starburst HDF 850.1 in a galaxy overdensity at z ≈ 5.2 in the Hubble Deep Field pp. 233-236

Fabian Walter, Roberto Decarli, Chris Carilli, Frank Bertoldi, Pierre Cox, Elisabete Da Cunha, Emanuele Daddi, Mark Dickinson, Dennis Downes, David Elbaz, Richard Ellis, Jacqueline Hodge, Roberto Neri, Dominik A. Riechers, Axel Weiss, Eric Bell, Helmut Dannerbauer, Melanie Krips, Mark Krumholz, Lindley Lentati, Roberto Maiolino, Karl Menten, Hans-Walter Rix, Brant Robertson, Hyron Spinrad, Dan P. Stark and Daniel Stern

Possible tropical lakes on Titan from observations of dark terrain pp. 237-239

Caitlin A. Griffith, Juan M. Lora, Jake Turner, Paulo F. Penteado, Robert H. Brown, Martin G. Tomasko, Lyn Doose and Charles See

A signature of cosmic-ray increase in ad 774–775 from tree rings in Japan pp. 240-242

Fusa Miyake, Kentaro Nagaya, Kimiaki Masuda and Toshio Nakamura

‘Big Bang’ tomography as a new route to atomic-resolution electron tomography pp. 243-246

Dirk Van Dyck, Joerg R. Jinschek and Fu-Rong Chen

Acanthodes and shark-like conditions in the last common ancestor of modern gnathostomes pp. 247-250

Samuel P. Davis, John A. Finarelli and Michael I. Coates

Covert skill learning in a cortical-basal ganglia circuit pp. 251-255

Jonathan D. Charlesworth, Timothy L. Warren and Michael S. Brainard

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2 pp. 256-260

Michael J. Schmeisser, Elodie Ey, Stephanie Wegener, Juergen Bockmann, A. Vanessa Stempel, Angelika Kuebler, Anna-Lena Janssen, Patrick T. Udvardi, Ehab Shiban, Christina Spilker, Detlef Balschun, Boris V. Skryabin, Susanne tom Dieck, Karl-Heinz Smalla, Dirk Montag, Claire S. Leblond, Philippe Faure, Nicolas Torquet, Anne-Marie Le Sourd, Roberto Toro, Andreas M. Grabrucker, Sarah A. Shoichet, Dietmar Schmitz, Michael R. Kreutz, Thomas Bourgeron, Eckart D. Gundelfinger and Tobias M. Boeckers

Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function pp. 261-265

Hyejung Won, Hye-Ryeon Lee, Heon Yung Gee, Won Mah, Jae-Ick Kim, Jiseok Lee, Seungmin Ha, Changuk Chung, Eun Suk Jung, Yi Sul Cho, Sae-Geun Park, Jung-Soo Lee, Kyungmin Lee, Daesoo Kim, Yong Chul Bae, Bong-Kiun Kaang, Min Goo Lee and Eunjoon Kim

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma pp. 266-270

Pedro A. Pérez-Mancera, Alistair G. Rust, Louise van der Weyden, Glen Kristiansen, Allen Li, Aaron L. Sarver, Kevin A. T. Silverstein, Robert Grützmann, Daniela Aust, Petra Rümmele, Thomas Knösel, Colin Herd, Derek L. Stemple, Ross Kettleborough, Jacqueline A. Brosnan, Ang Li, Richard Morgan, Spencer Knight, Jun Yu, Shane Stegeman, Lara S. Collier, Jelle J. ten Hoeve, Jeroen de Ridder, Alison P. Klein, Michael Goggins, Ralph H. Hruban, David K. Chang, Andrew V. Biankin, Sean M. Grimmond, Lodewyk F. A. Wessels, Stephen A. Wood, Christine A. Iacobuzio-Donahue, Christian Pilarsky, David A. Largaespada, David J. Adams and David A. Tuveson

Control of a Salmonella virulence locus by an ATP-sensing leader messenger RNA pp. 271-275

Eun-Jin Lee and Eduardo A. Groisman

Atomic model of the type III secretion system needle pp. 276-279

Antoine Loquet, Nikolaos G. Sgourakis, Rashmi Gupta, Karin Giller, Dietmar Riedel, Christian Goosmann, Christian Griesinger, Michael Kolbe, David Baker, Stefan Becker and Adam Lange

Retraction Note: DNA demethylation in hormone-induced transcriptional derepression pp. 280-280

Mi-Sun Kim, Takeshi Kondo, Ichiro Takada, Min-Young Youn, Yoko Yamamoto, Sayuri Takahashi, Takahiro Matsumoto, Sally Fujiyama, Yuko Shirode, Ikuko Yamaoka, Hirochika Kitagawa, Ken-Ichi Takeyama, Hiroshi Shibuya, Fumiaki Ohtake and Shigeaki Kato

Pharmaceutical sector: Delicate transition pp. 281-283

Charlotte Schubert

Turning point: Jim Hoch pp. 283-283

Virginia Gewin

Squealer pp. 286-286

Robert Nathan Correll

2012, volume 486, articles 7401

Turn Spain’s budget crisis into an opportunity pp. 7-7

Carmen Vela

President prunes forest reforms pp. 13-13

Jeff Tollefson

South Korea surrenders to creationist demands pp. 14-14

Soo Bin Park

Japan considers nuclear-free future pp. 15-15

David Cyranoski

Antibody alarm call rouses immune response to cancer pp. 16-16

Erika Check Hayden

Ancestry testing goes for pinpoint accuracy pp. 17-17

Ewen Callaway

Earth summit: Rio report card pp. 20-23

Jeff Tollefson and Natasha Gilbert

Lead by example pp. 25-26

Fabio Scarano, André Guimarães and José Maria da Silva

The corporate climate overhaul pp. 27-28

Pavan Sukhdev

Food security: Eating globally pp. 30-31

Tom MacMillan

Virology: The battle inside pp. 31-32

José Esparza

Psychology: Markets in mind pp. 32-32

Richard Lea

Q&A: The data visualizer pp. 33-33

Jascha Hoffman

Value of submerged early human sites pp. 34-34

Nicholas Flemming, Geoffrey N. Bailey and Dimitris Sakellariou

Two faces of marine ecology research pp. 34-34

Juerg Brunnschweiler

Villages project responds to criticism pp. 34-34

Paul Pronyk

Pitfalls of Romania's ethics council pp. 34-34

Octavian Voiculescu

Remote responsibility pp. 36-37

Edgar Hertwich

High-tech yeast ageing pp. 37-38

Michael Polymenis and Brian K. Kennedy

Young dwarfs date an old halo pp. 38-40

Timothy C. Beers

A dash of deep nebula on the rocks pp. 40-41

Chris J. Ballentine

Sibling neurons bond to share sensations pp. 41-42

Thomas D. Mrsic-Flogel and Tobias Bonhoeffer

Electrocatalyst approaches and challenges for automotive fuel cells pp. 43-51

Mark K. Debe

Approaching a state shift in Earth’s biosphere pp. 52-58

Anthony D. Barnosky, Elizabeth A. Hadly, Jordi Bascompte, Eric L. Berlow, James H. Brown, Mikael Fortelius, Wayne M. Getz, John Harte, Alan Hastings, Pablo A. Marquet, Neo D. Martinez, Arne Mooers, Peter Roopnarine, Geerat Vermeij, John W. Williams, Rosemary Gillespie, Justin Kitzes, Charles Marshall, Nicholas Matzke, David P. Mindell, Eloy Revilla and Adam B. Smith

Biodiversity loss and its impact on humanity pp. 59-67

Bradley J. Cardinale, J. Emmett Duffy, Andrew Gonzalez, David U. Hooper, Charles Perrings, Patrick Venail, Anita Narwani, Georgina M. Mace, David Tilman, David A. Wardle, Ann P. Kinzig, Gretchen C. Daily, Michel Loreau, James B. Grace, Anne Larigauderie, Diane S. Srivastava and Shahid Naeem

Securing natural capital and expanding equity to rescale civilization pp. 68-73

Paul R. Ehrlich, Peter M. Kareiva and Gretchen C. Daily

Cis-regulatory control of corticospinal system development and evolution pp. 74-79

Sungbo Shim, Kenneth Y. Kwan, Mingfeng Li, Veronique Lefebvre and Nenad Šestan

Chemical genetic discovery of targets and anti-targets for cancer polypharmacology pp. 80-84

Arvin C. Dar, Tirtha K. Das, Kevan M. Shokat and Ross L. Cagan

Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch pp. 85-89

Aiming Ren, Kanagalaghatta R. Rajashankar and Dinshaw J. Patel

The age of the Milky Way inner halo pp. 90-92

Jason S. Kalirai

Ultraviolet-radiation-induced methane emissions from meteorites and the Martian atmosphere pp. 93-96

Frank Keppler, Ivan Vigano, Andy McLeod, Ulrich Ott, Marion Früchtl and Thomas Röckmann

Late Miocene decoupling of oceanic warmth and atmospheric carbon dioxide forcing pp. 97-100

Jonathan P. LaRiviere, A. Christina Ravelo, Allison Crimmins, Petra S. Dekens, Heather L. Ford, Mitch Lyle and Michael W. Wara

Early differentiation and volatile accretion recorded in deep-mantle neon and xenon pp. 101-104

Sujoy Mukhopadhyay

A global synthesis reveals biodiversity loss as a major driver of ecosystem change pp. 105-108

David U. Hooper, E. Carol Adair, Bradley J. Cardinale, Jarrett E. K. Byrnes, Bruce A. Hungate, Kristin L. Matulich, Andrew Gonzalez, J. Emmett Duffy, Lars Gamfeldt and Mary I. O’Connor

International trade drives biodiversity threats in developing nations pp. 109-112

M. Lenzen, D. Moran, K. Kanemoto, B. Foran, L. Lobefaro and A. Geschke

Preferential electrical coupling regulates neocortical lineage-dependent microcircuit assembly pp. 113-117

Yong-Chun Yu, Shuijin He, She Chen, Yinghui Fu, Keith N. Brown, Xing-Hua Yao, Jian Ma, Kate P. Gao, Gina E. Sosinsky, Kun Huang and Song-Hai Shi

Clonally related visual cortical neurons show similar stimulus feature selectivity pp. 118-121

Ye Li, Hui Lu, Pei-lin Cheng, Shaoyu Ge, Huatai Xu, Song-Hai Shi and Yang Dan

α2δ expression sets presynaptic calcium channel abundance and release probability pp. 122-125

Michael B. Hoppa, Beatrice Lana, Wojciech Margas, Annette C. Dolphin and Timothy A. Ryan

An oxygen-regulated switch in the protein synthesis machinery pp. 126-129

James Uniacke, Chet E. Holterman, Gabriel Lachance, Aleksandra Franovic, Mathieu D. Jacob, Marc R. Fabian, Josianne Payette, Martin Holcik, Arnim Pause and Stephen Lee

Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel pp. 130-134

Xu Zhang, Wenlin Ren, Paul DeCaen, Chuangye Yan, Xiao Tao, Lin Tang, Jingjing Wang, Kazuya Hasegawa, Takashi Kumasaka, Jianhua He, Jiawei Wang, David E. Clapham and Nieng Yan

Crystal structure of a voltage-gated sodium channel in two potentially inactivated states pp. 135-139

Jian Payandeh, Tamer M. Gamal El-Din, Todd Scheuer, Ning Zheng and William A. Catterall

Building better biobanks pp. 141-146

Monya Baker

Dental science: Oral observatory pp. 147-148

Roberta Kwok

Turning point: Rachel O'Reilly pp. 149-149

Katharine Sanderson

After experiment seven pp. 152-152

Michael W. Lucht