miRNAs trigger widespread epigenetically activated siRNAs from transposons in Arabidopsis

Kate M. Creasey, Jixian Zhai, Filipe Borges, Frederic Van Ex, Michael Regulski, Blake C. Meyers and Robert A. Martienssen ()
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Kate M. Creasey: Cold Spring Harbor Laboratory, 1 Bungtown Road
Jixian Zhai: 15 Innovation Way, University of Delaware
Filipe Borges: Cold Spring Harbor Laboratory, 1 Bungtown Road
Frederic Van Ex: Cold Spring Harbor Laboratory, 1 Bungtown Road
Michael Regulski: Cold Spring Harbor Laboratory, 1 Bungtown Road
Blake C. Meyers: 15 Innovation Way, University of Delaware
Robert A. Martienssen: Cold Spring Harbor Laboratory, 1 Bungtown Road

Nature, 2014, vol. 508, issue 7496, 411-415

Abstract: The generation of widespread epigenetically activated short interfering RNAs by the targeting of microRNAs to transposon transcripts in Arabidopsis thaliana is shown to be a latent mechanism that only becomes active when the transcripts are epigenetically reactivated, for example, during reprogramming of the germ line.

Date: 2014
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DOI: 10.1038/nature13069

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