Apical constriction drives tissue-scale hydrodynamic flow to mediate cell elongation

Bing He, Konstantin Doubrovinski, Oleg Polyakov and Eric Wieschaus ()
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Bing He: Princeton University
Konstantin Doubrovinski: Princeton University
Oleg Polyakov: Princeton University
Eric Wieschaus: Princeton University

Nature, 2014, vol. 508, issue 7496, 392-396

Abstract: The lengthening phase of ventral furrow formation in Drosophila gastrulation is driven by cytoplasmic flows triggered by apical constriction of mesoderm cells independent of the mechanical inputs from the basolateral membranes.

Date: 2014
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DOI: 10.1038/nature13070

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