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2019, volume 567, articles 7749

Publisher Correction: β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration pp. E15-E15

Dmitri Lodygin, Moritz Hermann, Nils Schweingruber, Cassandra Flügel-Koch, Takashi Watanabe, Corinna Schlosser, Arianna Merlini, Henrike Körner, Hsin-Fang Chang, Henrike J. Fischer, Holger M. Reichardt, Marta Zagrebelsky, Brit Mollenhauer, Sebastian Kügler, Dirk Fitzner, Jens Frahm, Christine Stadelmann, Michael Haberl, Francesca Odoardi and Alexander Flügel

Offbeat approaches to cancer research pp. S27-S29

Nic Fleming

Career Guide: Germany pp. S33-S33

Sarah O’Meara

An introduction to the complexities of the German research scene pp. S34-S35

Hristio Boytchev

How Germany is winning at turning its research to commercial application pp. S38-S40

Neil Savage

Ten reasons to move to Germany as a researcher pp. S44-S45

Denise Hruby

Scientists in Germany identify first hybrid hominin pp. S45-S45

Neil Savage

The science of starting a new life pp. S46-S47

Denise Hruby

British chemist battles xenophobia in Germany pp. S47-S47

Hristio Boytchev

Germany faces its future as a pioneer in sustainability and renewable energy pp. S51-S53

Andrew Curry

The second coming of solar pp. S53-S53

Andrew Curry

Ten research collaborations between Germany and the rest of the world pp. S56-S57

Eva Wolfangel

Sexism is still a problem for German research pp. S60-S62

Denise Hruby

Preceded by 967 men: meet the first woman in charge of the 600-year-old Leipzig University pp. S61-S61

Denise Hruby

Germany’s attitude to start-up firms is undergoing profound change pp. S64-S65

Andrew Curry

No more career headaches pp. S65-S65

Andrew Curry

Plagiarism detectors are a crutch, and a problem pp. 435-435

Debora Weber-Wulff

Fresh look at Apollo Moon rocks reveals Solar System secrets pp. 441-442

Alexandra Witze

Antarctic project to drill for oldest-ever ice core pp. 442-443

Quirin Schiermeier

Canada budget overlooks basic research pp. 443-444

Brian Owens

World Health Organization panel weighs in on CRISPR-babies debate pp. 444-445

Sara Reardon

Universities spooked by Trump order tying free speech to grants pp. 445-446

Sara Reardon

Why the sexes don’t feel pain the same way pp. 448-450

Amber Dance

Why the US–China trade war spells disaster for the Amazon pp. 451-454

Richard Fuchs, Peter Alexander, Calum Brown, Frances Cossar, Roslyn C. Henry and Mark Rounsevell

Globe to gut: inside Big Food pp. 456-457

Felicity Lawrence

The joy of stats pp. 458-459

Evelyn Lamb

Fighting for air, mathematical mayhem, and beguiling bats: Books in brief pp. 459-459

Barbara Kiser

Brexit threatens biosecurity — from data to strategy pp. 461-461

D. H. Browne, David C. Aldridge, Catherine Rhodes and William Sutherland

Retiring statistical significance would give bias a free pass pp. 461-461

John P. A. Ioannidis

Raise the bar rather than retire significance pp. 461-461

Valen E. Johnson

Make polluters pay for fluorochemical clean-up pp. 461-461

Pam Miller and Joe DiGangi

Retire significance, but still test hypotheses pp. 461-461

Julia M. Haaf, Alexander Ly and Eric-Jan Wagenmakers

Bill Carter Jenkins (1945–2019) pp. 462-462

Susan M. Reverby

Modification of histone proteins by serotonin in the nucleus pp. 464-465

Marlene Cervantes and Paolo Sassone-Corsi

Solar cells boosted by an improved charge-carrying material pp. 465-467

Liyuan Han

Effects of dengue immunity on Zika virus infection pp. 467-468

Stephen S. Whitehead and Theodore C. Pierson

The next step in making arrays of single atoms pp. 468-470

Mark Saffman

Refrigeration based on plastic crystals pp. 470-471

Claudio Cazorla

Ratcheting up lipopolysaccharide transport pp. 471-472

Russell E. Bishop

The expanding landscape of ‘oncohistone’ mutations in human cancers pp. 473-478

Benjamin A. Nacev, Lijuan Feng, John D. Bagert, Agata E. Lemiesz, JianJiong Gao, Alexey A. Soshnev, Ritika Kundra, Nikolaus Schultz, Tom W. Muir and C. David Allis

Neoantigen-directed immune escape in lung cancer evolution pp. 479-485

Rachel Rosenthal, Elizabeth Larose Cadieux, Roberto Salgado, Maise Al Bakir, David A. Moore, Crispin T. Hiley, Tom Lund, Miljana Tanić, James L. Reading, Kroopa Joshi, Jake Y. Henry, Ehsan Ghorani, Gareth A. Wilson, Nicolai J. Birkbak, Mariam Jamal-Hanjani, Selvaraju Veeriah, Zoltan Szallasi, Sherene Loi, Matthew D. Hellmann, Andrew Feber, Benny Chain, Javier Herrero, Sergio A. Quezada, Jonas Demeulemeester, Peter Loo, Stephan Beck, Nicholas McGranahan and Charles Swanton

Structural basis of lipopolysaccharide extraction by the LptB2FGC complex pp. 486-490

Yanyan Li, Benjamin J. Orlando and Maofu Liao

Error mitigation extends the computational reach of a noisy quantum processor pp. 491-495

Abhinav Kandala, Kristan Temme, Antonio D. Córcoles, Antonio Mezzacapo, Jerry M. Chow and Jay M. Gambetta

Observation of unconventional chiral fermions with long Fermi arcs in CoSi pp. 496-499

Zhicheng Rao, Hang Li, Tiantian Zhang, Shangjie Tian, Chenghe Li, Binbin Fu, Cenyao Tang, Le Wang, Zhilin Li, Wenhui Fan, Jiajun Li, Yaobo Huang, Zhehong Liu, Youwen Long, Chen Fang, Hongming Weng, Youguo Shi, Hechang Lei, Yujie Sun, Tian Qian and Hong Ding

Topological chiral crystals with helicoid-arc quantum states pp. 500-505

Daniel S. Sanchez, Ilya Belopolski, Tyler A. Cochran, Xitong Xu, Jia-Xin Yin, Guoqing Chang, Weiwei Xie, Kaustuv Manna, Vicky Süß, Cheng-Yi Huang, Nasser Alidoust, Daniel Multer, Songtian S. Zhang, Nana Shumiya, Xirui Wang, Guang-Qiang Wang, Tay-Rong Chang, Claudia Felser, Su-Yang Xu, Shuang Jia, Hsin Lin and M. Zahid Hasan

Colossal barocaloric effects in plastic crystals pp. 506-510

Bing Li, Yukinobu Kawakita, Seiko Ohira-Kawamura, Takeshi Sugahara, Hui Wang, Jingfan Wang, Yanna Chen, Saori I. Kawaguchi, Shogo Kawaguchi, Koji Ohara, Kuo Li, Dehong Yu, Richard Mole, Takanori Hattori, Tatsuya Kikuchi, Shin-ichiro Yano, Zhao Zhang, Zhe Zhang, Weijun Ren, Shangchao Lin, Osami Sakata, Kenji Nakajima and Zhidong Zhang

Efficient, stable and scalable perovskite solar cells using poly(3-hexylthiophene) pp. 511-515

Eui Hyuk Jung, Nam Joong Jeon, Eun Young Park, Chan Su Moon, Tae Joo Shin, Tae-Youl Yang, Jun Hong Noh and Jangwon Seo

Managing nitrogen to restore water quality in China pp. 516-520

ChaoQing Yu, Xiao Huang, Han Chen, H. Charles J. Godfray, Jonathon S. Wright, Jim W. Hall, Peng Gong, ShaoQiang Ni, ShengChao Qiao, GuoRui Huang, YuChen Xiao, Jie Zhang, Zhao Feng, XiaoTang Ju, Philippe Ciais, Nils Chr. Stenseth, Dag O. Hessen, Zhanli Sun, Le Yu, WenJia Cai, HaoHuan Fu, XiaoMeng Huang, Chi Zhang, HongBin Liu and James Taylor

Efficacy of MEK inhibition in patients with histiocytic neoplasms pp. 521-524

Eli L. Diamond, Benjamin H. Durham, Gary A. Ulaner, Esther Drill, Justin Buthorn, Michelle Ki, Lillian Bitner, Hana Cho, Robert J. Young, Jasmine H. Francis, Raajit Rampal, Mario Lacouture, Lynn A. Brody, Neval Ozkaya, Ahmet Dogan, Neal Rosen, Alexia Iasonos, Omar Abdel-Wahab and David M. Hyman

Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction pp. 525-529

Xindong Liu, Yun Wang, Huiping Lu, Jing Li, Xiaowei Yan, Minglu Xiao, Jing Hao, Andrei Alekseev, Hiep Khong, Tenghui Chen, Rui Huang, Jin Wu, Qiwen Zhao, Qi Wu, Senlin Xu, Xiaohu Wang, Wei Jin, Shicang Yu, Yan Wang, Lai Wei, Aibo Wang, Bo Zhong, Ling Ni, Xiaolong Liu, Roza Nurieva, Lilin Ye, Qiang Tian, Xiu-Wu Bian and Chen Dong

NR4A transcription factors limit CAR T cell function in solid tumours pp. 530-534

Joyce Chen, Isaac F. López-Moyado, Hyungseok Seo, Chan-Wang J. Lio, Laura J. Hempleman, Takashi Sekiya, Akihiko Yoshimura, James P. Scott-Browne and Anjana Rao

Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3 pp. 535-539

Lorna A. Farrelly, Robert E. Thompson, Shuai Zhao, Ashley E. Lepack, Yang Lyu, Natarajan V. Bhanu, Baichao Zhang, Yong-Hwee E. Loh, Aarthi Ramakrishnan, Krishna C. Vadodaria, Kelly J. Heard, Galina Erikson, Tomoyoshi Nakadai, Ryan M. Bastle, Bradley J. Lukasak, Henry Zebroski, Natalia Alenina, Michael Bader, Olivier Berton, Robert G. Roeder, Henrik Molina, Fred H. Gage, Li Shen, Benjamin A. Garcia, Haitao Li, Tom W. Muir and Ian Maze

Glucocorticoids promote breast cancer metastasis pp. 540-544

Milan M. S. Obradović, Baptiste Hamelin, Nenad Manevski, Joana Pinto Couto, Atul Sethi, Marie-May Coissieux, Simone Münst, Ryoko Okamoto, Hubertus Kohler, Alexander Schmidt and Mohamed Bentires-Alj

Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase pp. 545-549

Steffi Herold, Jacqueline Kalb, Gabriele Büchel, Carsten P. Ade, Apoorva Baluapuri, Jiajia Xu, Jan Koster, Daniel Solvie, Anne Carstensen, Christina Klotz, Sabrina Rodewald, Christina Schülein-Völk, Matthias Dobbelstein, Elmar Wolf, Jan Molenaar, Rogier Versteeg, Susanne Walz and Martin Eilers

Structural basis of unidirectional export of lipopolysaccharide to the cell surface pp. 550-553

Tristan W. Owens, Rebecca J. Taylor, Karanbir S. Pahil, Blake R. Bertani, Natividad Ruiz, Andrew C. Kruse and Daniel Kahne

Cellular censuses to guide cancer care pp. 555-557

Michael Eisenstein

Five scientists explain how they decided whether to move to another country for their work or studies pp. 559-561

Virginia Gewin

How I self-advocate for researchers with disabilities and illnesses pp. 561-561

Virginia Gewin

The librarian pp. 564-564

Robert Dawson

2019, volume 567, articles 7748

Materials science is helping to transform China into a high-tech economy pp. S1-S5

Sarah O’Meara

The Chinese researcher painting the printing industry green pp. S3-S3

Sarah O’Meara

High-pressure research and a return to China: meet Haiyan Zheng pp. S5-S5

Sarah O’Meara

Japan expands international scientific links pp. S7-S7

Catherine Armitage

Japanese universities test collaboration pp. S9-S11

David McNeill

Japan’s global connectors pp. S12-S17

Catherine Armitage, David McNeill and Smriti Mallapaty

Author Correction: Hundred-fold enhancement in far-field radiative heat transfer over the blackbody limit pp. E12-E12

Dakotah Thompson, Linxiao Zhu, Rohith Mittapally, Seid Sadat, Zhen Xing, Patrick McArdle, M. Mumtaz Qazilbash, Pramod Reddy and Edgar Meyhofer

Author Correction: Trade-offs in using European forests to meet climate objectives pp. E13-E13

Sebastiaan Luyssaert, Guillaume Marie, Aude Valade, Yi-Ying Chen, Sylvestre Njakou Djomo, James Ryder, Juliane Otto, Kim Naudts, Anne Sofie Lansø, Josefine Ghattas and Matthew J. McGrath

Publisher Correction: Damage-tolerant architected materials inspired by crystal microstructure pp. E14-E14

Minh-Son Pham, Chen Liu, Iain Todd and Jedsada Lertthanasarn

Unconscious bias limits women’s careers pp. S22-S23

Smriti Mallapaty

Japan’s start-up gulf pp. S24-S25

Smriti Mallapaty

The World Bank must clean up its act pp. 285-285

Vijaya Ramachandran

Thousands of scientists are backing the kids striking for climate change pp. 291-292

Matthew Warren

Bull ‘super dads’ are being engineered to produce sperm from another father pp. 292-293

Heidi Ledford

English sea walls get wired to measure flood risk in real time pp. 294-295

Alexandra Witze

Scientists track damage from controversial deep-sea mining method pp. 294-294

Olive Heffernan

Soap-bubble pioneer is first woman to win prestigious maths prize pp. 295-296

Davide Castelvecchi

Protein-slaying drugs could be the next blockbuster therapies pp. 298-300

Megan Scudellari

Antibiotics set to flood Florida’s troubled orange orchards pp. 302-303

Maryn McKenna

Scientists rise up against statistical significance pp. 305-307

Valentin Amrhein, Sander Greenland and Blake McShane

Evolving society: why humanity coheres pp. 308-309

Agustín Fuentes

The rise and fall of scientific authority — and how to bring it back pp. 309-310

Robert P. Crease

Manage forests as protection against warming pp. 311-311

James E. M. Watson, Tom D. Evans, Oscar Venter and Sean L. Maxwell

Author lists: include original language script and unique identifiers pp. 311-311

Zhongmin Wang

Supercollider critics should learn from history pp. 311-311

John Ellis

Science looks worse because it’s getting better pp. 311-311

Dashun Wang

Three more unsung women – astatine discovery pp. 311-311

Brett Thornton and Shawn Burdette

Robotic collectives inspired by biological cells pp. 314-315

Metin Sitti

Pore-forming small molecules offer a promising way to tackle cystic fibrosis pp. 315-317

David N. Sheppard and Anthony P. Davis

Enzymes trapped and zapped for use outside cells pp. 317-318

Alison Narayan

X-ray chimneys in the Galactic Centre pp. 318-320

Masha Chernyakova

The influence of a single neuron on its network pp. 320-321

Ikuko T. Smith

Structures of STING protein illuminate this key regulator of inflammation pp. 321-322

Andrea Ablasser

Van der Waals integration before and beyond two-dimensional materials pp. 323-333

Yuan Liu, Yu Huang and Xiangfeng Duan

Single-neuron perturbations reveal feature-specific competition in V1 pp. 334-340

Selmaan N. Chettih and Christopher D. Harvey

Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma pp. 341-346

Yufeng Shi, S. Kyun Lim, Qiren Liang, Swathi V. Iyer, Hua-Yu Wang, Zilai Wang, Xuanhua Xie, Daochun Sun, Yu-Jung Chen, Viviane Tabar, Philip Gutin, Noelle Williams, Jef K. Brabander and Luis F. Parada

An X-ray chimney extending hundreds of parsecs above and below the Galactic Centre pp. 347-350

G. Ponti, F. Hofmann, E. Churazov, M. R. Morris, F. Haberl, K. Nandra, R. Terrier, M. Clavel and A. Goldwurm

Random anti-lasing through coherent perfect absorption in a disordered medium pp. 351-355

Kevin Pichler, Matthias Kühmayer, Julian Böhm, Andre Brandstötter, Philipp Ambichl, Ulrich Kuhl and Stefan Rotter

Photonic topological insulator in synthetic dimensions pp. 356-360

Eran Lustig, Steffen Weimann, Yonatan Plotnik, Yaakov Lumer, Miguel A. Bandres, Alexander Szameit and Mordechai Segev

Particle robotics based on statistical mechanics of loosely coupled components pp. 361-365

Shuguang Li, Richa Batra, David Brown, Hyun-Dong Chang, Nikhil Ranganathan, Chuck Hoberman, Daniela Rus and Hod Lipson

Diverse and robust molecular algorithms using reprogrammable DNA self-assembly pp. 366-372

Damien Woods, David Doty, Cameron Myhrvold, Joy Hui, Felix Zhou, Peng Yin and Erik Winfree

Deacylative transformations of ketones via aromatization-promoted C–C bond activation pp. 373-378

Yan Xu, Xiaotian Qi, Pengfei Zheng, Carlo C. Berti, Peng Liu and Guangbin Dong

Deep electrical imaging of the ultraslow-spreading Mohns Ridge pp. 379-383

Ståle Emil Johansen, Martin Panzner, Rune Mittet, Hans E. F. Amundsen, Anna Lim, Eirik Vik, Martin Landrø and Børge Arntsen

Feature-selective encoding of substrate vibrations in the forelimb somatosensory cortex pp. 384-388

Mario Prsa, Karin Morandell, Géraldine Cuenu and Daniel Huber

Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP pp. 389-393

Guijun Shang, Conggang Zhang, Zhijian J. Chen, Xiao-chen Bai and Xuewu Zhang

Structural basis of STING binding with and phosphorylation by TBK1 pp. 394-398

Conggang Zhang, Guijun Shang, Xiang Gui, Xuewu Zhang, Xiao-chen Bai and Zhijian J. Chen

Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups pp. 399-404

Oscar M. Rueda, Stephen-John Sammut, Jose A. Seoane, Suet-Feung Chin, Jennifer L. Caswell-Jin, Maurizio Callari, Rajbir Batra, Bernard Pereira, Alejandra Bruna, H. Raza Ali, Elena Provenzano, Bin Liu, Michelle Parisien, Cheryl Gillett, Steven McKinney, Andrew R. Green, Leigh Murphy, Arnie Purushotham, Ian O. Ellis, Paul D. Pharoah, Cristina Rueda, Samuel Aparicio, Carlos Caldas and Christina Curtis

Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia pp. 405-408

Katrina A. Muraglia, Rajeev S. Chorghade, Bo Ram Kim, Xiao Xiao Tang, Viral S. Shah, Anthony S. Grillo, Page N. Daniels, Alexander G. Cioffi, Philip H. Karp, Lingyang Zhu, Michael J. Welsh and Martin D. Burke

Mechanism of DNA translocation underlying chromatin remodelling by Snf2 pp. 409-413

Meijing Li, Xian Xia, Yuanyuan Tian, Qi Jia, Xiaoyu Liu, Ying Lu, Ming Li, Xueming Li and Zhucheng Chen

Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally pp. 414-419

Huilin Huang, Hengyou Weng, Keren Zhou, Tong Wu, Boxuan Simen Zhao, Mingli Sun, Zhenhua Chen, Xiaolan Deng, Gang Xiao, Franziska Auer, Lars Klemm, Huizhe Wu, Zhixiang Zuo, Xi Qin, Yunzhu Dong, Yile Zhou, Hanjun Qin, Shu Tao, Juan Du, Jun Liu, Zhike Lu, Hang Yin, Ana Mesquita, Celvie L. Yuan, Yueh-Chiang Hu, Wenju Sun, Rui Su, Lei Dong, Chao Shen, Chenying Li, Ying Qing, Xi Jiang, Xiwei Wu, Miao Sun, Jun-Lin Guan, Lianghu Qu, Minjie Wei, Markus Müschen, Gang Huang, Chuan He, Jianhua Yang and Jianjun Chen

Discovery of a pathway for terminal-alkyne amino acid biosynthesis pp. 420-424

J. A. Marchand, M. E. Neugebauer, M. C. Ing, C.-I. Lin, J. G. Pelton and M. C. Y. Chang

Five ways media training helped me to boost the impact of my research pp. 425-426

Caroline Kamau

A picture is worth pp. 428-428

Beth Cato

2019, volume 567, articles 7747

Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations pp. E5-E9

Eunju Kang, Jun Wu, Nuria Marti Gutierrez, Amy Koski, Rebecca Tippner-Hedges, Karen Agaronyan, Aida Platero-Luengo, Paloma Martinez-Redondo, Hong Ma, Yeonmi Lee, Tomonari Hayama, Crystal Dyken, Xinjian Wang, Shiyu Luo, Riffat Ahmed, Ying Li, Dongmei Ji, Refik Kayali, Cengiz Cinnioglu, Susan Olson, Jeffrey Jensen, David Battaglia, David Lee, Diana Wu, Taosheng Huang, Don P. Wolf, Dmitry Temiakov, Juan Carlos Izpisua Belmonte, Paula Amato and Shoukhrat Mitalipov

Author Correction: Structural insights into the activation of metabotropic glutamate receptors pp. E10-E10

Antoine Koehl, Hongli Hu, Dan Feng, Bingfa Sun, Yan Zhang, Michael J. Robertson, Matthew Chu, Tong Sun Kobilka, Toon Laeremans, Jan Steyaert, Jeffrey Tarrasch, Somnath Dutta, Rasmus Fonseca, William I. Weis, Jesper M. Mathiesen, Georgios Skiniotis and Brian K. Kobilka

Author Correction: Systems of mechanized and reactive droplets powered by multi-responsive surfactants pp. E11-E11

Zhijie Yang, Jingjing Wei, Yaroslav I. Sobolev and Bartosz A. Grzybowski

How Africa can quell the next disease outbreaks pp. 147-147

John N. Nkengasong

Violence propels Ebola outbreak towards 1,000 cases pp. 153-154

Amy Maxmen

Cuba acknowledges climate change threats in its constitution pp. 155-155

Emiliano Rodríguez Mega

How AI and satellites could help predict volcanic eruptions pp. 156-157

Alexandra Witze

Geoengineering debate shifts to UN environment assembly pp. 156-156

Jeff Tollefson

The mouse in the video game pp. 158-160

Liam Drew

How secret conversations inside cells are transforming biology pp. 162-164

Elie Dolgin

Adopt a moratorium on heritable genome editing pp. 165-168

Eric S. Lander, Françoise Baylis, Feng Zhang, Emmanuelle Charpentier, Paul Berg, Catherine Bourgain, Bärbel Friedrich, J. Keith Joung, Jinsong Li, David Liu, Luigi Naldini, Jing-Bao Nie, Renzong Qiu, Bettina Schoene-Seifert, Feng Shao, Sharon Terry, Wensheng Wei and Ernst-Ludwig Winnacker

How 2D semiconductors could extend Moore’s law pp. 169-170

Ming-Yang Li, Sheng-Kai Su, H.-S. Philip Wong and Lain-Jong Li

How algorithms could bring empathy back to medicine pp. 172-173

Thomas R. Insel

The wild side of discovery, a history of information warfare, and the immune system uncovered: Books in brief pp. 173-173

Barbara Kiser

Academies’ action plan for germline editing pp. 175-175

Victor J. Dzau, Marcia McNutt and Venki Ramakrishnan

NIH supports call for moratorium on clinical uses of germline gene editing pp. 175-175

Carrie D. Wolinetz and Francis S. Collins

Scientists, help keep coal in the ground pp. 175-175

Andrea Arratia-Solar

“Work on problems you most enjoy” — Munk’s legacy pp. 175-175

John O. Dabiri

Walter Munk (1917-2019) pp. 176-176

Carl Wunsch

A newly discovered stem cell that keeps bones growing pp. 178-179

Manuela Wuelling and Andrea Vortkamp

Machine learning in quantum spaces pp. 179-181

Maria Schuld

Molecular envoys pave the way for pancreatic cancer to invade the liver pp. 181-182

Anirban Maitra

Forty years of fathoming life in hot springs on the ocean floor pp. 182-184

Cindy Lee Van Dover

Molecular-decoration technique offers boost to medicinal chemists pp. 184-185

Eric M. Ferreira

Battling disease by giving mosquitoes an antimalarial drug pp. 185-186

Janet Hemingway

An integrative systems genetic analysis of mammalian lipid metabolism pp. 187-193

Benjamin L. Parker, Anna C. Calkin, Marcus M. Seldin, Michael F. Keating, Elizabeth J. Tarling, Pengyi Yang, Sarah C. Moody, Yingying Liu, Eser J. Zerenturk, Elise J. Needham, Matthew L. Miller, Bethan L. Clifford, Pauline Morand, Matthew J. Watt, Ruth C. R. Meex, Kang-Yu Peng, Richard Lee, Kaushala Jayawardana, Calvin Pan, Natalie A. Mellett, Jacquelyn M. Weir, Ross Lazarus, Aldons J. Lusis, Peter J. Meikle, David E. James, Thomas Q. Aguiar Vallim and Brian G. Drew

Bacterial cGAS-like enzymes synthesize diverse nucleotide signals pp. 194-199

Aaron T. Whiteley, James B. Eaglesham, Carina C. de Oliveira Mann, Benjamin R. Morehouse, Brianna Lowey, Eric A. Nieminen, Olga Danilchanka, David S. King, Amy S. Y. Lee, John J. Mekalanos and Philip J. Kranzusch

A distance to the Large Magellanic Cloud that is precise to one per cent pp. 200-203

G. Pietrzyński, D. Graczyk, A. Gallenne, W. Gieren, I. B. Thompson, B. Pilecki, P. Karczmarek, M. Górski, K. Suchomska, M. Taormina, B. Zgirski, P. Wielgórski, Z. Kołaczkowski, P. Konorski, S. Villanova, N. Nardetto, P. Kervella, F. Bresolin, R. P. Kudritzki, J. Storm, R. Smolec and W. Narloch

Optical clock comparison for Lorentz symmetry testing pp. 204-208

Christian Sanner, Nils Huntemann, Richard Lange, Christian Tamm, Ekkehard Peik, Marianna S. Safronova and Sergey G. Porsev

Supervised learning with quantum-enhanced feature spaces pp. 209-212

Vojtěch Havlíček, Antonio D. Córcoles, Kristan Temme, Aram W. Harrow, Abhinav Kandala, Jerry M. Chow and Jay M. Gambetta

Electrical resistivity across a nematic quantum critical point pp. 213-217

S. Licciardello, J. Buhot, J. Lu, J. Ayres, S. Kasahara, Y. Matsuda, T. Shibauchi and N. E. Hussey

Thermodynamic signatures of quantum criticality in cuprate superconductors pp. 218-222

B. Michon, C. Girod, S. Badoux, J. Kačmarčík, Q. Ma, M. Dragomir, H. A. Dabkowska, B. D. Gaulin, J.-S. Zhou, S. Pyon, T. Takayama, H. Takagi, S. Verret, N. Doiron-Leyraud, C. Marcenat, L. Taillefer and T. Klein

Site-selective and versatile aromatic C−H functionalization by thianthrenation pp. 223-228

Florian Berger, Matthew B. Plutschack, Julian Riegger, Wanwan Yu, Samira Speicher, Matthew Ho, Nils Frank and Tobias Ritter

Self-formed bedrock waterfalls pp. 229-233

Joel S. Scheingross, Michael P. Lamb and Brian M. Fuller

A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate pp. 234-238

Phillip T. Newton, Lei Li, Baoyi Zhou, Christoph Schweingruber, Maria Hovorakova, Meng Xie, Xiaoyan Sun, Lakshmi Sandhow, Artem V. Artemov, Evgeny Ivashkin, Simon Suter, Vyacheslav Dyachuk, Maha El Shahawy, Amel Gritli-Linde, Thibault Bouderlique, Julian Petersen, Annelie Mollbrink, Joakim Lundeberg, Grigori Enikolopov, Hong Qian, Kaj Fried, Maria Kasper, Eva Hedlund, Igor Adameyko, Lars Sävendahl and Andrei S. Chagin

Exposing Anopheles mosquitoes to antimalarials blocks Plasmodium parasite transmission pp. 239-243

Douglas G. Paton, Lauren M. Childs, Maurice A. Itoe, Inga E. Holmdahl, Caroline O. Buckee and Flaminia Catteruccia

S-Geranylgeranyl-l-glutathione is a ligand for human B cell-confinement receptor P2RY8 pp. 244-248

Erick Lu, Finn D. Wolfreys, Jagan R. Muppidi, Ying Xu and Jason G. Cyster

Hepatocytes direct the formation of a pro-metastatic niche in the liver pp. 249-252

Jae W. Lee, Meredith L. Stone, Paige M. Porrett, Stacy K. Thomas, Chad A. Komar, Joey H. Li, Devora Delman, Kathleen Graham, Whitney L. Gladney, Xia Hua, Taylor A. Black, Austin L. Chien, Krishna S. Majmundar, Jeffrey C. Thompson, Stephanie S. Yee, Mark H. O’Hara, Charu Aggarwal, Dong Xin, Abraham Shaked, Mingming Gao, Dexi Liu, Mitesh J. Borad, Ramesh K. Ramanathan, Erica L. Carpenter, Ailing Ji, Maria C. Beer, Frederick C. Beer, Nancy R. Webb and Gregory L. Beatty

p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis pp. 253-256

Le Li, Youxiang Mao, Lina Zhao, Lijia Li, Jinjun Wu, Mengjia Zhao, Wenjing Du, Li Yu and Peng Jiang

Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma pp. 257-261

Ying Jiang, Aihua Sun, Yang Zhao, Wantao Ying, Huichuan Sun, Xinrong Yang, Baocai Xing, Wei Sun, Liangliang Ren, Bo Hu, Chaoying Li, Li Zhang, Guangrong Qin, Menghuan Zhang, Ning Chen, Manli Zhang, Yin Huang, Jinan Zhou, Yan Zhao, Mingwei Liu, Xiaodong Zhu, Yang Qiu, Yanjun Sun, Cheng Huang, Meng Yan, Mingchao Wang, Wei Liu, Fang Tian, Huali Xu, Jian Zhou, Zhenyu Wu, Tieliu Shi, Weimin Zhu, Jun Qin, Lu Xie, Jia Fan, Xiaohong Qian and Fuchu He

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway pp. 262-266

Xiang Gui, Hui Yang, Tuo Li, Xiaojun Tan, Peiqing Shi, Minghao Li, Fenghe Du and Zhijian J. Chen

TRAIP is a master regulator of DNA interstrand crosslink repair pp. 267-272

R. Alex Wu, Daniel R. Semlow, Ashley N. Kamimae-Lanning, Olga V. Kochenova, Gheorghe Chistol, Michael R. Hodskinson, Ravindra Amunugama, Justin L. Sparks, Meng Wang, Lin Deng, Claudia A. Mimoso, Emily Low, Ketan J. Patel and Johannes C. Walter

What 50 principal investigators taught me about my failure to land tenure pp. 273-275

Bela Z. Schmidt

How a biophysicist became a beacon of hope in the Middle East pp. 275-275

Kendall Powell

Please [redacted] my last e-mail pp. 278-278

Kurt Pankau

2019, volume 567, articles 7746

Author Correction: Predictable and precise template-free CRISPR editing of pathogenic variants pp. E1-E2

Max W. Shen, Mandana Arbab, Jonathan Y. Hsu, Daniel Worstell, Sannie J. Culbertson, Olga Krabbe, Christopher A. Cassa, David R. Liu, David K. Gifford and Richard I. Sherwood

Author Correction: El Niño–Southern Oscillation complexity pp. E3-E3

Axel Timmermann, Soon-Il An, Jong-Seong Kug, Fei-Fei Jin, Wenju Cai, Antonietta Capotondi, Kim M. Cobb, Matthieu Lengaigne, Michael J. McPhaden, Malte F. Stuecker, Karl Stein, Andrew T. Wittenberg, Kyung-Sook Yun, Tobias Bayr, Han-Ching Chen, Yoshimitsu Chikamoto, Boris Dewitte, Dietmar Dommenget, Pamela Grothe, Eric Guilyardi, Yoo-Geun Ham, Michiya Hayashi, Sarah Ineson, Daehyun Kang, Sunyong Kim, WonMoo Kim, June-Yi Lee, Tim Li, Jing-Jia Luo, Shayne McGregor, Yann Planton, Scott Power, Harun Rashid, Hong-Li Ren, Agus Santoso, Ken Takahashi, Alexander Todd, Guomin Wang, Guojian Wang, Ruihuang Xie, Woo-Hyun Yang, Sang-Wook Yeh, Jinho Yoon, Elke Zeller and Xuebin Zhang

Author Correction: Inference of ecological and social drivers of human brain-size evolution pp. E4-E4

Mauricio González-Forero and Andy Gardner

Policies designed for drugs won’t work for AI pp. 7-7

Melanie Smallman

Chinese crew extract first rock from beneath East Antarctic ice in 60 years pp. 13-14

Alexandra Witze

Sexual harassment rife in Australian science, suggests first workplace survey pp. 14-15

Bianca Nogrady

Huge US university cancels subscription with Elsevier pp. 15-16

Nisha Gaind

Night-vision ‘super-mice’ created using light-converting nanoparticles pp. 16-17

Matthew Warren

Pioneering ‘live-code’ article allows scientists to play with each other’s results pp. 17-18

Jeffrey M. Perkel

Paul Nurse on Brexit: ‘UK is sleepwalking into a disaster’ pp. 18-19

Elizabeth Gibney

The fight for control over virtual fossils pp. 20-23

Dyani Lewis

Four steps to global management of space traffic pp. 25-27

Jamie Morin

The debated legacy of Einstein’s first wife pp. 28-29

Ann Finkbeiner

How research erases women, the prehistory of Polynesia, and everything you wanted to know about beer: Books in brief pp. 29-29

Barbara Kiser

Leprosy: the world’s oldest human-rights issue pp. 30-30

Ann Aerts

Uncertain future for women scientists in Brazil pp. 31-31

Ronildo Alves Benício

Support smallholders to step up Nigeria’s cassava yields pp. 31-31

Hemant Nitturkar

Tax fossil-fuel production, not emissions pp. 31-31

Emil Roduner

Thousands of Danish children find ten new bacteria species pp. 31-31

Christian Sonne and Aage K. O. Alstrup

‘Moral machine’ experiment is no basis for policymaking pp. 31-31

Barry Dewitt, Baruch Fischhoff and Nils-Eric Sahlin

Manfred Eigen (1927–2019) pp. 32-32

Georgina Ferry

When cooperators cheat pp. 34-35

Andrew G. Zink and John M. Eadie

Receptor for bat influenza virus uncovers potential risk to humans pp. 35-36

Wendy S. Barclay

Scrambling of quantum information validated by quantum teleportation pp. 36-37

Jonathan Home

Ancient plants escaped the end-Permian mass extinction pp. 38-39

Robert A. Gastaldo

Materials in flatland twist and shine pp. 39-40

Bernhard Urbaszek and Ajit Srivastava

Unstable genomes promote inflammation pp. 41-42

Sarah Lambert

Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells pp. 43-48

Kenichiro Furuyama, Simona Chera, Léon Gurp, Daniel Oropeza, Luiza Ghila, Nicolas Damond, Heidrun Vethe, Joao A. Paulo, Antoinette M. Joosten, Thierry Berney, Domenico Bosco, Craig Dorrell, Markus Grompe, Helge Ræder, Bart O. Roep, Fabrizio Thorel and Pedro L. Herrera

Colonic epithelial cell diversity in health and inflammatory bowel disease pp. 49-55

Kaushal Parikh, Agne Antanaviciute, David Fawkner-Corbett, Marta Jagielowicz, Anna Aulicino, Christoffer Lagerholm, Simon Davis, James Kinchen, Hannah H. Chen, Nasullah Khalid Alham, Neil Ashley, Errin Johnson, Philip Hublitz, Leyuan Bao, Joanna Lukomska, Rajinder Singh Andev, Elisabet Björklund, Benedikt M. Kessler, Roman Fischer, Robert Goldin, Hashem Koohy and Alison Simmons

Structure of the IFNγ receptor complex guides design of biased agonists pp. 56-60

Juan L. Mendoza, Nichole K. Escalante, Kevin M. Jude, Junel Sotolongo Bellon, Leon Su, Tim M. Horton, Naotaka Tsutsumi, Steven J. Berardinelli, Robert S. Haltiwanger, Jacob Piehler, Edgar G. Engleman and K. Christopher Garcia

Verified quantum information scrambling pp. 61-65

K. A. Landsman, C. Figgatt, T. Schuster, N. M. Linke, B. Yoshida, N. Y. Yao and C. Monroe

Signatures of moiré-trapped valley excitons in MoSe2/WSe2 heterobilayers pp. 66-70

Kyle L. Seyler, Pasqual Rivera, Hongyi Yu, Nathan P. Wilson, Essance L. Ray, David G. Mandrus, Jiaqiang Yan, Wang Yao and Xiaodong Xu

Evidence for moiré excitons in van der Waals heterostructures pp. 71-75

Kha Tran, Galan Moody, Fengcheng Wu, Xiaobo Lu, Junho Choi, Kyounghwan Kim, Amritesh Rai, Daniel A. Sanchez, Jiamin Quan, Akshay Singh, Jacob Embley, André Zepeda, Marshall Campbell, Travis Autry, Takashi Taniguchi, Kenji Watanabe, Nanshu Lu, Sanjay K. Banerjee, Kevin L. Silverman, Suenne Kim, Emanuel Tutuc, Li Yang, Allan H. MacDonald and Xiaoqin Li

Observation of moiré excitons in WSe2/WS2 heterostructure superlattices pp. 76-80

Chenhao Jin, Emma C. Regan, Aiming Yan, M. Iqbal Bakti Utama, Danqing Wang, Sihan Zhao, Ying Qin, Sijie Yang, Zhiren Zheng, Shenyang Shi, Kenji Watanabe, Takashi Taniguchi, Sefaattin Tongay, Alex Zettl and Feng Wang

Resonantly hybridized excitons in moiré superlattices in van der Waals heterostructures pp. 81-86

Evgeny M. Alexeev, David A. Ruiz-Tijerina, Mark Danovich, Matthew J. Hamer, Daniel J. Terry, Pramoda K. Nayak, Seongjoon Ahn, Sangyeon Pak, Juwon Lee, Jung Inn Sohn, Maciej R. Molas, Maciej Koperski, Kenji Watanabe, Takashi Taniguchi, Kostya S. Novoselov, Roman V. Gorbachev, Hyeon Suk Shin, Vladimir I. Fal’ko and Alexander I. Tartakovskii

Molecular streaming and its voltage control in ångström-scale channels pp. 87-90

T. Mouterde, A. Keerthi, A. R. Poggioli, S. A. Dar, A. Siria, A. K. Geim, L. Bocquet and B. Radha

Wetland carbon storage controlled by millennial-scale variation in relative sea-level rise pp. 91-95

Kerrylee Rogers, Jeffrey J. Kelleway, Neil Saintilan, J. Patrick Megonigal, Janine B. Adams, James R. Holmquist, Meng Lu, Lisa Schile-Beers, Atun Zawadzki, Debashish Mazumder and Colin D. Woodroffe

Social parasitism as an alternative reproductive tactic in a cooperatively breeding cuckoo pp. 96-99

Christina Riehl and Meghan J. Strong

Neuromodulatory control of localized dendritic spiking in critical period cortex pp. 100-104

Courtney E. Yaeger, Dario L. Ringach and Joshua T. Trachtenberg

Female-biased embryonic death from inflammation induced by genomic instability pp. 105-108

Adrian J. McNairn, Chen-Hua Chuang, Jordana C. Bloom, Marsha D. Wallace and John C. Schimenti

MHC class II proteins mediate cross-species entry of bat influenza viruses pp. 109-112

Umut Karakus, Thiprampai Thamamongood, Kevin Ciminski, Wei Ran, Sira C. Günther, Marie O. Pohl, Davide Eletto, Csaba Jeney, Donata Hoffmann, Sven Reiche, Jan Schinköthe, Reiner Ulrich, Julius Wiener, Michael G. B. Hayes, Max W. Chang, Annika Hunziker, Emilio Yángüez, Teresa Aydillo, Florian Krammer, Josua Oderbolz, Matthias Meier, Annette Oxenius, Anne Halenius, Gert Zimmer, Christopher Benner, Benjamin G. Hale, Adolfo García-Sastre, Martin Beer, Martin Schwemmle and Silke Stertz

The centrosome protein AKNA regulates neurogenesis via microtubule organization pp. 113-117

Germán Camargo Ortega, Sven Falk, Pia A. Johansson, Elise Peyre, Loïc Broix, Sanjeeb Kumar Sahu, William Hirst, Thomas Schlichthaerle, Camino Juan Romero, Kalina Draganova, Stanislav Vinopal, Kaviya Chinnappa, Anna Gavranovic, Tugay Karakaya, Thomas Steininger, Juliane Merl-Pham, Regina Feederle, Wei Shao, Song-Hai Shi, Stefanie M. Hauck, Ralf Jungmann, Frank Bradke, Victor Borrell, Arie Geerlof, Simone Reber, Vijay K. Tiwari, Wieland B. Huttner, Michaela Wilsch-Bräuninger, Laurent Nguyen and Magdalena Götz

Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death pp. 118-122

Javier Garcia-Bermudez, Lou Baudrier, Erol Can Bayraktar, Yihui Shen, Konnor La, Rohiverth Guarecuco, Burcu Yucel, Danilo Fiore, Bernardo Tavora, Elizaveta Freinkman, Sze Ham Chan, Caroline Lewis, Wei Min, Giorgio Inghirami, David M. Sabatini and Kıvanç Birsoy

Complete biosynthesis of cannabinoids and their unnatural analogues in yeast pp. 123-126

Xiaozhou Luo, Michael A. Reiter, Leo d’Espaux, Jeff Wong, Charles M. Denby, Anna Lechner, Yunfeng Zhang, Adrian T. Grzybowski, Simon Harth, Weiyin Lin, Hyunsu Lee, Changhua Yu, John Shin, Kai Deng, Veronica T. Benites, George Wang, Edward E. K. Baidoo, Yan Chen, Ishaan Dev, Christopher J. Petzold and Jay D. Keasling

Structural basis for KCTD-mediated rapid desensitization of GABAB signalling pp. 127-131

Sanduo Zheng, Nohely Abreu, Joshua Levitz and Andrew C. Kruse

Retraction Note: A homing system targets therapeutic T cells to brain cancer pp. 132-132

Heba Samaha, Antonella Pignata, Kristen Fousek, Jun Ren, Fong W. Lam, Fabio Stossi, Julien Dubrulle, Vita S. Salsman, Shanmugarajan Krishnan, Sung-Ha Hong, Matthew L. Baker, Ankita Shree, Ahmed Z. Gad, Thomas Shum, Dai Fukumura, Tiara T. Byrd, Malini Mukherjee, Sean P. Marrelli, Jordan S. Orange, Sujith K. Joseph, Poul H. Sorensen, Michael D. Taylor, Meenakshi Hegde, Maksim Mamonkin, Rakesh K. Jain, Shahenda El-Naggar and Nabil Ahmed

AI empowers conservation biology pp. 133-134

Roberta Kwok

The professional advisers who can help you to move from academia to industry pp. 135-137

David Payne

My move from postdoc to career adviser pp. 137-137

David Payne

The last child pp. 140-140

L. R. Conti