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2013, volume 493, articles 7434

Does consumption rate scale superlinearly? pp. E1-E2

Henrique C. Giacomini, Brian J. Shuter, Derrick T. de Kerckhove and Peter A. Abrams

Heart health pp. S1-S1

Mike May

Pawar et al. reply pp. E2-E3

Samraat Pawar, Anthony I. Dell and Savage Van M.

Cardiovascular disease: Biochemistry to behaviour pp. S2-S3

Bill Cannon

Public planning: Designs fit for purpose pp. S4-S5

Duncan Graham-Rowe

Perspective: The power of disease prevention pp. S6-S6

Joep Perk

Diagnostics: The new risk predictors pp. S7-S8

Peter Gwynne

Perspective: A tale of two receptors pp. S9-S9

Sébastien Foulquier, Ulrike Muscha Steckelings and Thomas Unger

Pathology: At the heart of the problem pp. S10-S11

Cassandra Willyard

Physiology: Beating stroke pp. S12-S13

Neil Savage

Drugs: Blood battles pp. S14-S15

Katharine Gammon

Psychology: Mind over myocardium pp. S16-S17

Shailaja Neelakantan

Scottish science is ready to go it alone pp. 579-579

Colin Macilwain

Research prize boost for Europe pp. 585-586

Alison Abbott and Quirin Schiermeier

UK research councils could face mergers pp. 586-586

Geoff Brumfiel

Coffee rust regains foothold pp. 587-587

Daniel Cressey

Funding agencies urged to check for duplicate grants pp. 588-589

Eugenie Samuel Reich and Conor L Myhrvold

Magnetic logic makes for mutable chips pp. 589-590

Geoff Brumfiel

Obama rekindles climate hopes pp. 590-591

Jeff Tollefson

Planetary science: Caught in the act pp. 592-596

Maggie McKee

Ocean conservation: A big fight over little fish pp. 597-598

Brendan Borrell

Same work, twice the money? pp. 599-601

Harold R. Garner, Lauren J. McIver and Michael B. Waitzkin

Scientific genius is extinct pp. 602-602

Dean Keith Simonton

Military technology: Deadly ingenuity pp. 604-605

Sharon Weinberger

History of science: Elements of romance pp. 606-606

Mark Peplow

History: Creator — or creationist? pp. 607-607

Kevin Padian

Revived species: how would they survive? pp. 608-608

Diogo Veríssimo and Laure Cugnière

Revived species: where will they live? pp. 608-608

J. Grant C. Hopcraft, Markus Borner and Daniel T. Haydon

Concern over US nuclear stewardship pp. 608-608

David Sharp and Merri Wood-Schultz

Mauritius threatens its own biodiversity pp. 608-609

F. B. Vincent Florens

Sustain the future by doing more with less pp. 609-609

Brian G. Fitzgerald

Dead language still alive for botanists pp. 609-609

Adam T. Halamski

Transmission studies resume for avian flu pp. 609-609

Ron A. M. Fouchier, Adolfo García-Sastre and Yoshihiro Kawaoka

Carl Woese (1928–2012) pp. 610-610

Harry Noller

A social rearrangement pp. 612-613

Andrew F. G. Bourke and Judith E. Mank

The planetary hypothesis revived pp. 613-614

Paul Charbonneau

Spliceosome's core exposed pp. 615-616

Charles C. Query and Maria M. Konarska

The depths of nitrogen cycling pp. 616-618

Maren Voss and Susanna Hietanen

Synthetic polymers with biological rigidity pp. 619-619

Margaret Lise Gardel

Hidden is more pp. 619-620

Qimiao Si

Hastatic order in the heavy-fermion compound URu2Si2 pp. 621-626

Premala Chandra, Piers Coleman and Rebecca Flint

Towards germline gene therapy of inherited mitochondrial diseases pp. 627-631

Masahito Tachibana, Paula Amato, Michelle Sparman, Joy Woodward, Dario Melguizo Sanchis, Hong Ma, Nuria Marti Gutierrez, Rebecca Tippner-Hedges, Eunju Kang, Hyo-Sang Lee, Cathy Ramsey, Keith Masterson, David Battaglia, David Lee, Diana Wu, Jeffrey Jensen, Phillip Patton, Sumita Gokhale, Richard Stouffer and Shoukhrat Mitalipov

Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants pp. 632-637

Daniel Paull, Valentina Emmanuele, Keren A. Weiss, Nathan Treff, Latoya Stewart, Haiqing Hua, Matthew Zimmer, David J. Kahler, Robin S. Goland, Scott A. Noggle, Robert Prosser, Michio Hirano, Mark V. Sauer and Dieter Egli

Crystal structure of Prp8 reveals active site cavity of the spliceosome pp. 638-643

Wojciech P. Galej, Chris Oubridge, Andrew J. Newman and Kiyoshi Nagai

An old disk still capable of forming a planetary system pp. 644-646

Edwin A. Bergin, L. Ilsedore Cleeves, Uma Gorti, Ke Zhang, Geoffrey A. Blake, Joel D. Green, Sean M. Andrews, Neal J. Evans, Thomas Henning, Karin Öberg, Klaus Pontoppidan, Chunhua Qi, Colette Salyk and Ewine F. van Dishoeck

Magnetic ratchet for three-dimensional spintronic memory and logic pp. 647-650

Reinoud Lavrijsen, Ji-Hyun Lee, Amalio Fernández-Pacheco, Dorothée C. M. C. Petit, Rhodri Mansell and Russell P. Cowburn

Responsive biomimetic networks from polyisocyanopeptide hydrogels pp. 651-655

Paul H. J. Kouwer, Matthieu Koepf, Vincent A. A. Le Sage, Maarten Jaspers, Arend M. van Buul, Zaskia H. Eksteen-Akeroyd, Tim Woltinge, Erik Schwartz, Heather J. Kitto, Richard Hoogenboom, Stephen J. Picken, Roeland J. M. Nolte, Eduardo Mendes and Alan E. Rowan

Divergent global precipitation changes induced by natural versus anthropogenic forcing pp. 656-659

Jian Liu, Bin Wang, Mark A. Cane, So-Young Yim and June-Yi Lee

Deep instability of deforested tropical peatlands revealed by fluvial organic carbon fluxes pp. 660-663

Sam Moore, Chris D. Evans, Susan E. Page, Mark H. Garnett, Tim G. Jones, Chris Freeman, Aljosja Hooijer, Andrew J. Wiltshire, Suwido H. Limin and Vincent Gauci

A Y-like social chromosome causes alternative colony organization in fire ants pp. 664-668

John Wang, Yannick Wurm, Mingkwan Nipitwattanaphon, Oksana Riba-Grognuz, Yu-Ching Huang, DeWayne Shoemaker and Laurent Keller

Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo pp. 669-673

Sophia Vrontou, Allan M. Wong, Kristofer K. Rau, H. Richard Koerber and David J. Anderson

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice pp. 674-678

Michael T. Heneka, Markus P. Kummer, Andrea Stutz, Andrea Delekate, Stephanie Schwartz, Ana Vieira-Saecker, Angelika Griep, Daisy Axt, Anita Remus, Te-Chen Tzeng, Ellen Gelpi, Annett Halle, Martin Korte, Eicke Latz and Douglas T. Golenbock

Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival pp. 679-683

Alejo Efeyan, Roberto Zoncu, Steven Chang, Iwona Gumper, Harriet Snitkin, Rachel L. Wolfson, Oktay Kirak, David D. Sabatini and David M. Sabatini

Visualization of splenic marginal zone B-cell shuttling and follicular B-cell egress pp. 684-688

Tal I. Arnon, Robert M. Horton, Irina L. Grigorova and Jason G. Cyster

Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence pp. 689-693

Peng Jiang, Wenjing Du, Anthony Mancuso, Kathryn E. Wellen and Xiaolu Yang

Identification of small RNA pathway genes using patterns of phylogenetic conservation and divergence pp. 694-698

Yuval Tabach, Allison C. Billi, Gabriel D. Hayes, Martin A. Newman, Or Zuk, Harrison Gabel, Ravi Kamath, Keren Yacoby, Brad Chapman, Susana M. Garcia, Mark Borowsky, John K. Kim and Gary Ruvkun

The architecture of human general transcription factor TFIID core complex pp. 699-702

Christoph Bieniossek, Gabor Papai, Christiane Schaffitzel, Frederic Garzoni, Maxime Chaillet, Elisabeth Scheer, Petros Papadopoulos, Laszlo Tora, Patrick Schultz and Imre Berger

Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures pp. 703-707

Satoshi Arai, Shinya Saijo, Kano Suzuki, Kenji Mizutani, Yoshimi Kakinuma, Yoshiko Ishizuka-Katsura, Noboru Ohsawa, Takaho Terada, Mikako Shirouzu, Shigeyuki Yokoyama, So Iwata, Ichiro Yamato and Takeshi Murata

Correction: Corrigendum: Resolving the evolutionary relationships of molluscs with phylogenomic tools pp. 708-708

Stephen A. Smith, Nerida G. Wilson, Freya E. Goetz, Caitlin Feehery, Sónia C. S. Andrade, Greg W. Rouse, Gonzalo Giribet and Casey W. Dunn

Better connected pp. 709-710

Mark Fishman, Robert Cross and Brigitta Tadmor

Turning point: Carl Boettiger pp. 711-711

Virginia Gewin

To my father pp. 714-714

David G. Blake

2013, volume 493, articles 7433

Ensuring health in universal health coverage pp. 453-453

James D Shelton

Greenland defied ancient warming pp. 459-460

Quirin Schiermeier

Work resumes on lethal flu strains pp. 460-460

Declan Butler

Researchers debate oil-spill remedy pp. 461-461

Mark Schrope

International aid projects come under the microscope pp. 462-463

Natasha Gilbert

Fresh bid to see exo-Earths pp. 464-465

Ron Cowen

Japan’s stimulus package showers science with cash pp. 465-465

David Cyranoski

Mapping brain networks: Fish-bowl neuroscience pp. 466-468

Virginia Hughes

Social evolution: The ritual animal pp. 470-472

Dan Jones

A vision for data science pp. 473-475

Chris A. Mattmann

The rebound effect is overplayed pp. 475-476

Kenneth Gillingham, Matthew J. Kotchen, David Rapson and Gernot Wagner

Anthropology: Power of the past pp. 477-478

Monique Borgerhoff Mulder

History: Frozen assets pp. 478-479

Edmund Stump

Science petitions are a facade of numbers pp. 480-480

Robert J. Warren and Mark A. Bradford

Small collections make a big impact pp. 480-480

Kevin Winker and Jack J. Withrow

Obesity: Multiple factors contribute pp. 480-480

Kristin Hamre

Obesity: Appetite hormone weighs in pp. 480-480

Stephan J. Guyenet

Undo NIH policy to ease effect of cuts pp. 480-480

Robert Benezra

Chance thrown by inaccurate dice pp. 480-480

Janet K. Burg

Strength in numbers pp. 482-483

Morgan Sheng, Roberto Malinow and Richard Huganir

Biofuel production on the margins pp. 483-484

Klaus Butterbach-Bahl and Ralf Kiese

50 & 100 Years Ago pp. 484-484

Struther Arnott and W. H. Bragg

Towards ever smaller length scales pp. 485-486

Peter Cargill

Gritting their teeth pp. 486-487

Bernard Wood

The to and fro of tumour spread pp. 487-488

Bryce J. W. van Denderen and Erik W. Thompson

LTP requires a reserve pool of glutamate receptors independent of subunit type pp. 495-500

Adam J. Granger, Yun Shi, Wei Lu, Manuel Cerpas and Roger A. Nicoll

Energy release in the solar corona from spatially resolved magnetic braids pp. 501-503

J. W. Cirtain, L. Golub, A. R. Winebarger, B. De Pontieu, K. Kobayashi, R. L. Moore, R. W. Walsh, K. E. Korreck, M. Weber, P. McCauley, A. Title, S. Kuzin and C. E. DeForest

Laser cooling of a semiconductor by 40 kelvin pp. 504-508

Jun Zhang, Dehui Li, Renjie Chen and Qihua Xiong

Interface-engineered templates for molecular spin memory devices pp. 509-513

Karthik V. Raman, Alexander M. Kamerbeek, Arup Mukherjee, Nicolae Atodiresei, Tamal K. Sen, Predrag Lazić, Vasile Caciuc, Reent Michel, Dietmar Stalke, Swadhin K. Mandal, Stefan Blügel, Markus Münzenberg and Jagadeesh S. Moodera

Sustainable bioenergy production from marginal lands in the US Midwest pp. 514-517

Ilya Gelfand, Ritvik Sahajpal, Xuesong Zhang, R. César Izaurralde, Katherine L. Gross and G. Philip Robertson

Stable creeping fault segments can become destructive as a result of dynamic weakening pp. 518-521

Hiroyuki Noda and Nadia Lapusta

Earliest evidence for cheese making in the sixth millennium bc in northern Europe pp. 522-525

Mélanie Salque, Peter I. Bogucki, Joanna Pyzel, Iwona Sobkowiak-Tabaka, Ryszard Grygiel, Marzena Szmyt and Richard P. Evershed

Insights into bilaterian evolution from three spiralian genomes pp. 526-531

Oleg Simakov, Ferdinand Marletaz, Sung-Jin Cho, Eric Edsinger-Gonzales, Paul Havlak, Uffe Hellsten, Dian-Han Kuo, Tomas Larsson, Jie Lv, Detlev Arendt, Robert Savage, Kazutoyo Osoegawa, Pieter de Jong, Jane Grimwood, Jarrod A. Chapman, Harris Shapiro, Andrea Aerts, Robert P. Otillar, Astrid Y. Terry, Jeffrey L. Boore, Igor V. Grigoriev, David R. Lindberg, Elaine C. Seaver, David A. Weisblat, Nicholas H. Putnam and Daniel S. Rokhsar

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons pp. 532-536

Dipesh Chaudhury, Jessica J. Walsh, Allyson K. Friedman, Barbara Juarez, Stacy M. Ku, Ja Wook Koo, Deveroux Ferguson, Hsing-Chen Tsai, Lisa Pomeranz, Daniel J. Christoffel, Alexander R. Nectow, Mats Ekstrand, Ana Domingos, Michelle S. Mazei-Robison, Ezekiell Mouzon, Mary Kay Lobo, Rachael L. Neve, Jeffrey M. Friedman, Scott J. Russo, Karl Deisseroth, Eric J. Nestler and Ming-Hu Han

Dopamine neurons modulate neural encoding and expression of depression-related behaviour pp. 537-541

Kay M. Tye, Julie J. Mirzabekov, Melissa R. Warden, Emily A. Ferenczi, Hsing-Chen Tsai, Joel Finkelstein, Sung-Yon Kim, Avishek Adhikari, Kimberly R. Thompson, Aaron S. Andalman, Lisa A. Gunaydin, Ilana B. Witten and Karl Deisseroth

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells pp. 542-546

Oliver D. K. Maddocks, Celia R. Berkers, Susan M. Mason, Liang Zheng, Karen Blyth, Eyal Gottlieb and Karen H. Vousden

Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation pp. 547-551

Ignacio J. Juncadella, Alexandra Kadl, Ashish K. Sharma, Yun M. Shim, Amelia Hochreiter-Hufford, Larry Borish and Kodi S. Ravichandran

Functional and evolutionary insight from the crystal structure of rubella virus protein E1 pp. 552-556

Rebecca M. DuBois, Marie-Christine Vaney, M. Alejandra Tortorici, Rana Al Kurdi, Giovanna Barba-Spaeth, Thomas Krey and Félix A. Rey

RNAi triggered by specialized machinery silences developmental genes and retrotransposons pp. 557-560

Soichiro Yamanaka, Sameet Mehta, Francisca E. Reyes-Turcu, Fanglei Zhuang, Ryan T. Fuchs, Yikang Rong, Gregory B. Robb and Shiv I. S. Grewal

TET2 promotes histone O-GlcNAcylation during gene transcription pp. 561-564

Qiang Chen, Yibin Chen, Chunjing Bian, Ryoji Fujiki and Xiaochun Yu

Clinical research: Conducting a trial pp. 565-567

Kelly Rae Chi

The shortlist pp. 570-570

Adam Kucharski

2013, volume 493, articles 7432

China has the capacity to lead in carbon trading pp. 273-273

Qiang Wang

HIV trial under scrutiny pp. 279-280

Meredith Wadman

Insider trading sparks concerns pp. 280-281

Heidi Ledford

Court lifts cloud over embryonic stem cells pp. 282-282

Monya Baker

Quantum dots go on display pp. 283-283

Katherine Bourzac

Behaviour genes unearthed pp. 284-284

Ewen Callaway

Vaccine switch urged for polio endgame pp. 285-285

Ewen Callaway

Scientific families: Dynasty pp. 286-289

Ed Yong

Fukushima: Fallout of fear pp. 290-293

Geoff Brumfiel

Time to model all life on Earth pp. 295-297

Drew Purves, Jörn P. W. Scharlemann, Mike Harfoot, Tim Newbold, Derek P. Tittensor, Jon Hutton and Stephen Emmott

Two years of blogging the NIH pp. 298-299

Sally Rockey

Conservation: The commonness of rarity pp. 300-301

Stuart Pimm

Statistics: Number-crunching in the raw pp. 301-301

David L. Vaux

Film: Walking the edge at Sundance pp. 302-302

Jascha Hoffman

Rat reality show blurs quality control pp. 304-304

Jerome R. Ravetz, Peter Healey and Steve Rayner

Cancer goal: Deadline will not erode trust pp. 304-304

Frances Visco

Cancer goal: Vaccine is cause for optimism pp. 304-304

Stephen Albert Johnston

Tie carbon emissions to consumers pp. 304-305

Zhu Liu, Fengming Xi and Dabo Guan

Sexism: Measure journal objectivity pp. 305-305

Boyan K. Garvalov

Sexism: Control experimental bias pp. 305-305

Letitia Meynell

Sexism: Conferences should seek a balance pp. 305-305

Jennifer L. Martin

More trials needed to assess sleeping pills pp. 305-305

Maximilian Moser and Daniel F. Kripke

Toe-clipping vital to amphibian research pp. 305-305

Décio T. Corrêa

Missing data mean holes in tree of life pp. 305-305

Bryan T. Drew

Rita Levi-Montalcini (1909–2012) pp. 306-306

Ralph A. Bradshaw

A history of give and take pp. 308-309

Steven M. Holland

Plumbing nickel from the core pp. 309-310

Michael J. Walter

Surf the waves of reprogramming pp. 310-311

Ignacio Sancho-Martinez and Juan Carlos Izpisua Belmonte

Memory and the single molecule pp. 312-313

Paul W. Frankland and Sheena A. Josselyn

Genes for home-building pp. 312-312

Patrick Goymer

Defects visualized in porous solids pp. 313-314

Christian Serre

Trustworthy predictions pp. 314-315

Paul R. C. Kent

Frontiers in biology pp. 317-317

Francesca Cesari, I-han Chou, Angela K. Eggleston, Marie-Thérèse Heemels, Barbara Marte and Ursula Weiss

Cytosystems dynamics in self-organization of tissue architecture pp. 318-326

Yoshiki Sasai

Activity-dependent neuronal signalling and autism spectrum disorder pp. 327-337

Daniel H. Ebert and Michael E. Greenberg

mTOR is a key modulator of ageing and age-related disease pp. 338-345

Simon C. Johnson, Peter S. Rabinovitch and Matt Kaeberlein

Metabolism of inflammation limited by AMPK and pseudo-starvation pp. 346-355

Luke A. J. O'Neill and D. Grahame Hardie

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks pp. 356-363

Molly C. Kottemann and Agata Smogorzewska

Towards an exact description of electronic wavefunctions in real solids pp. 365-370

George H. Booth, Andreas Grüneis, Georg Kresse and Ali Alavi

Autism-related deficits via dysregulated eIF4E-dependent translational control pp. 371-377

Christos G. Gkogkas, Arkady Khoutorsky, Israeli Ran, Emmanouil Rampakakis, Tatiana Nevarko, Daniel B. Weatherill, Cristina Vasuta, Stephanie Yee, Morgan Truitt, Paul Dallaire, François Major, Paul Lasko, Davide Ruggero, Karim Nader, Jean-Claude Lacaille and Nahum Sonenberg

Pulsed accretion in a variable protostar pp. 378-380

James Muzerolle, Elise Furlan, Kevin Flaherty, Zoltan Balog and Robert Gutermuth

Planetary system disruption by Galactic perturbations to wide binary stars pp. 381-384

Nathan A. Kaib, Sean N. Raymond and Martin Duncan

Ultrahard nanotwinned cubic boron nitride pp. 385-388

Yongjun Tian, Bo Xu, Dongli Yu, Yanming Ma, Yanbin Wang, Yingbing Jiang, Wentao Hu, Chengchun Tang, Yufei Gao, Kun Luo, Zhisheng Zhao, Li-Min Wang, Bin Wen, Julong He and Zhongyuan Liu

Multidecadal variability in East African hydroclimate controlled by the Indian Ocean pp. 389-392

Jessica E. Tierney, Jason E. Smerdon, Kevin J. Anchukaitis and Richard Seager

Nickel and helium evidence for melt above the core–mantle boundary pp. 393-397

Claude Herzberg, Paul D. Asimow, Dmitri A. Ionov, Chris Vidito, Matthew G. Jackson and Dennis Geist

Oceanographic controls on the diversity and extinction of planktonic foraminifera pp. 398-401

Shanan E. Peters, Daniel C. Kelly and Andrew J. Fraass

Discrete genetic modules are responsible for complex burrow evolution in Peromyscus mice pp. 402-405

Jesse N. Weber, Brant K. Peterson and Hopi E. Hoekstra

Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer pp. 406-410

Elise Ruark, Katie Snape, Peter Humburg, Chey Loveday, Ilirjana Bajrami, Rachel Brough, Daniel Nava Rodrigues, Anthony Renwick, Sheila Seal, Emma Ramsay, Silvana Del Vecchio Duarte, Manuel A. Rivas, Margaret Warren-Perry, Anna Zachariou, Adriana Campion-Flora, Sandra Hanks, Anne Murray, Naser Ansari Pour, Jenny Douglas, Lorna Gregory, Andrew Rimmer, Neil M. Walker, Tsun-Po Yang, Julian W. Adlard, Julian Barwell, Jonathan Berg, Angela F. Brady, Carole Brewer, Glen Brice, Cyril Chapman, Jackie Cook, Rosemarie Davidson, Alan Donaldson, Fiona Douglas, Diana Eccles, D. Gareth Evans, Lynn Greenhalgh, Alex Henderson, Louise Izatt, Ajith Kumar, Fiona Lalloo, Zosia Miedzybrodzka, Patrick J. Morrison, Joan Paterson, Mary Porteous, Mark T. Rogers, Susan Shanley, Lisa Walker, Martin Gore, Richard Houlston, Matthew A. Brown, Mark J. Caufield, Panagiotis Deloukas, Mark I. McCarthy, John A. Todd, Clare Turnbull, Jorge S. Reis-Filho, Alan Ashworth, Antonis C. Antoniou, Christopher J. Lord, Peter Donnelly and Nazneen Rahman

Exaggerated translation causes synaptic and behavioural aberrations associated with autism pp. 411-415

Emanuela Santini, Thu N. Huynh, Andrew F. MacAskill, Adam G. Carter, Philippe Pierre, Davide Ruggero, Hanoch Kaphzan and Eric Klann

Prkcz null mice show normal learning and memory pp. 416-419

Anna M. Lee, Benjamin R. Kanter, Dan Wang, Jana P. Lim, Mimi E. Zou, Chichen Qiu, Thomas McMahon, Jahan Dadgar, Sarah C. Fischbach-Weiss and Robert O. Messing

PKM-ζ is not required for hippocampal synaptic plasticity, learning and memory pp. 420-423

Lenora J. Volk, Julia L. Bachman, Richard Johnson, Yilin Yu and Richard L. Huganir

Asymmetric neurotransmitter release enables rapid odour lateralization in Drosophila pp. 424-428

Quentin Gaudry, Elizabeth J. Hong, Jamey Kain, Benjamin L. de Bivort and Rachel I. Wilson

Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system pp. 429-432

Joe Bondy-Denomy, April Pawluk, Karen L. Maxwell and Alan R. Davidson

Mammalian heart renewal by pre-existing cardiomyocytes pp. 433-436

Samuel E. Senyo, Matthew L. Steinhauser, Christie L. Pizzimenti, Vicky K. Yang, Lei Cai, Mei Wang, Ting-Di Wu, Jean-Luc Guerquin-Kern, Claude P. Lechene and Richard T. Lee

Structure and function of the initially transcribing RNA polymerase II–TFIIB complex pp. 437-440

Sarah Sainsbury, Jürgen Niesser and Patrick Cramer

Education: Free-range learning pp. 441-443

Virginia Gewin

Francis Collins: Changes at the NIH pp. 443-444

Gene Russo

Eros for Annabelle pp. 446-446

Ian Whates

2013, volume 493, articles 7431

Rumour research can douse digital wildfires pp. 135-135

Nicholas DiFonzo

Europe’s untamed carbon pp. 141-142

Richard Van Noorden

Electron beams set nanostructures aglow pp. 143-143

Eugenie Samuel Reich

Tough talk over mercury treaty pp. 144-145

Jane Qiu

Safety of induced stem cells gets a boost pp. 145-145

Monya Baker

‘Rehab’ helps errant researchers return to the lab pp. 147-147

Daniel Cressey

Dyscalculia: Number games pp. 150-153

Ewen Callaway

Planetary disasters: It could happen one night pp. 154-156

Nicola Jones

From patterns to predictions pp. 157-158

Carl Boettiger and Alan Hastings

Value all research products pp. 159-159

Heather Piwowar

Cetology: How science inspired Moby-Dick pp. 160-161

Philip Hoare

Innovation: Motley inventors pp. 162-162

John Browning

Fiscal cliff is bad news for US science pp. 163-163

Howard H. Garrison

A shortage of fertilizer resources? pp. 163-163

Tim Worstall

Patients self-treat with parasitic worms pp. 163-163

Stephen Flowers and Michael Hopkins

China's new leaders offer green hope pp. 163-163

Hong Yang, Roger J. Flower and Julian R. Thompson

Joseph E. Murray (1919–2012) pp. 164-164

Peter Morris

Time crystals pp. 166-167

Piers Coleman

Older but less wise pp. 167-168

Peter F. Sale

Topology matters pp. 168-168

Rosamund Daw

Led by the nose pp. 169-170

Philippe Janvier

Phased array on a fingertip pp. 170-171

Thomas F. Krauss

Insulin meets its receptor pp. 171-172

Stevan R. Hubbard

Wasted loops quantified pp. 172-173

Anna C. Balazs

How glaciers grow pp. 173-174

Simon H. Brocklehurst

Craniofacial development of hagfishes and the evolution of vertebrates pp. 175-180

Yasuhiro Oisi, Kinya G. Ota, Shigehiro Kuraku, Satoko Fujimoto and Shigeru Kuratani

Crystallographic snapshot of cellulose synthesis and membrane translocation pp. 181-186

Jacob L. W. Morgan, Joanna Strumillo and Jochen Zimmer

Bright radio emission from an ultraluminous stellar-mass microquasar in M 31 pp. 187-190

Matthew J. Middleton, James C. A. Miller-Jones, Sera Markoff, Rob Fender, Martin Henze, Natasha Hurley-Walker, Anna M. M. Scaife, Timothy P. Roberts, Dominic Walton, John Carpenter, Jean-Pierre Macquart, Geoffrey C. Bower, Mark Gurwell, Wolfgang Pietsch, Frank Haberl, Jonathan Harris, Michael Daniel, Junayd Miah, Chris Done, John S. Morgan, Hugh Dickinson, Phil Charles, Vadim Burwitz, Massimo Della Valle, Michael Freyberg, Jochen Greiner, Margarita Hernanz, Dieter H. Hartmann, Despina Hatzidimitriou, Arno Riffeser, Gloria Sala, Stella Seitz, Pablo Reig, Arne Rau, Marina Orio, David Titterington and Keith Grainge

Flows of gas through a protoplanetary gap pp. 191-194

Simon Casassus, Gerrit van der Plas, Sebastian Perez M, William R. F. Dent, Ed Fomalont, Janis Hagelberg, Antonio Hales, Andrés Jordán, Dimitri Mawet, Francois Ménard, Al Wootten, David Wilner, A. Meredith Hughes, Matthias R. Schreiber, Julien H. Girard, Barbara Ercolano, Hector Canovas, Pablo E. Román and Vachail Salinas

Large-scale nanophotonic phased array pp. 195-199

Jie Sun, Erman Timurdogan, Ami Yaacobi, Ehsan Shah Hosseini and Michael R. Watts

Topological colloids pp. 200-205

Bohdan Senyuk, Qingkun Liu, Sailing He, Randall D. Kamien, Robert B. Kusner, Tom C. Lubensky and Ivan I. Smalyukh

Glaciations in response to climate variations preconditioned by evolving topography pp. 206-210

Vivi Kathrine Pedersen and David Lundbek Egholm

Carbon-dioxide-rich silicate melt in the Earth’s upper mantle pp. 211-215

Rajdeep Dasgupta, Ananya Mallik, Kyusei Tsuno, Anthony C. Withers, Greg Hirth and Marc M. Hirschmann

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants pp. 216-220

Wenqing Fu, Timothy D. O’Connor, Goo Jun, Hyun Min Kang, Goncalo Abecasis, Suzanne M. Leal, Stacey Gabriel, Mark J. Rieder, David Altshuler, Jay Shendure, Deborah A. Nickerson, Michael J. Bamshad, Exome Sequencing Project Nhlbi and Joshua M. Akey

Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation pp. 221-225

Zhiqiang Yan, Wei Zhang, Ye He, David Gorczyca, Yang Xiang, Li E. Cheng, Shan Meltzer, Lily Yeh Jan and Yuh Nung Jan

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis pp. 226-230

Marlen Knobloch, Simon M. G. Braun, Luis Zurkirchen, Carolin von Schoultz, Nicola Zamboni, Marcos J. Araúzo-Bravo, Werner J. Kovacs, Özlem Karalay, Ueli Suter, Raquel A. C. Machado, Marta Roccio, Matthias P. Lutolf, Clay F. Semenkovich and Sebastian Jessberger

Control of somatic tissue differentiation by the long non-coding RNA TINCR pp. 231-235

Markus Kretz, Zurab Siprashvili, Ci Chu, Dan E. Webster, Ashley Zehnder, Kun Qu, Carolyn S. Lee, Ross J. Flockhart, Abigail F. Groff, Jennifer Chow, Danielle Johnston, Grace E. Kim, Robert C. Spitale, Ryan A. Flynn, Grace X. Y. Zheng, Subhadra Aiyer, Arjun Raj, John L. Rinn, Howard Y. Chang and Paul A. Khavari

COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis pp. 236-240

Jun Qin, San-Pin Wu, Chad J. Creighton, Fangyan Dai, Xin Xie, Chiang-Min Cheng, Anna Frolov, Gustavo Ayala, Xia Lin, Xin-Hua Feng, Michael M. Ittmann, Shaw-Jenq Tsai, Ming-Jer Tsai and Sophia Y. Tsai

How insulin engages its primary binding site on the insulin receptor pp. 241-245

John G. Menting, Jonathan Whittaker, Mai B. Margetts, Linda J. Whittaker, Geoffrey K.-W. Kong, Brian J. Smith, Christopher J. Watson, Lenka Žáková, Emília Kletvíková, Jiří Jiráček, Shu Jin Chan, Donald F. Steiner, Guy G. Dodson, Andrzej M. Brzozowski, Michael A. Weiss, Colin W. Ward and Michael C. Lawrence

Recombination-restarted replication makes inverted chromosome fusions at inverted repeats pp. 246-249

Ken’Ichi Mizuno, Izumi Miyabe, Stephanie A. Schalbetter, Antony M. Carr and Johanne M. Murray

Post-replicative repair involves separase-dependent removal of the kleisin subunit of cohesin pp. 250-254

Alexandra McAleenan, Andres Clemente-Blanco, Violeta Cordon-Preciado, Nicholas Sen, Miguel Esteras, Adam Jarmuz and Luis Aragón

Structure of the proton-gated urea channel from the gastric pathogen Helicobacter pylori pp. 255-258

David Strugatsky, Reginald McNulty, Keith Munson, Chiung-Kuang Chen, S. Michael Soltis, George Sachs and Hartmut Luecke

Graduate students: Structured study pp. 259-261

Amber Dance

Turning point: Rui Costa pp. 261-261

Virginia Gewin

Pest control pp. 264-264

John Frizell

2013, volume 493, articles 7430

Science must be seen to bridge the political divide pp. 7-7

Daniel Sarewitz

Safety survey reveals lab risks pp. 9-10

Richard Van Noorden

New year, new science pp. 11-11

Richard Van Noorden

Methane leaks erode green credentials of natural gas pp. 12-12

Jeff Tollefson

US fiscal deal leaves science vulnerable pp. 13-13

Heidi Ledford

Maxine Clarke (1954-2012) pp. 13-13

Philip Campbell

Infectious disease: TB's revenge pp. 14-16

Leigh Phillips

Improve weather forecasts for the developing world pp. 17-19

Peter J. Webster

Science today, history tomorrow pp. 19-21

Georgina Ferry

Hot tickets for 2013 in science and art pp. 22-23

Jascha Hoffman

Innovation: Limits be damned pp. 24-25

Cyrus C. M. Mody

Astrobiology: The cosmological you pp. 25-25

Birger Schmitz

NIH funding: Agency rebuts critique pp. 26-26

George Santangelo and David J. Lipman

NIH funding: It does support innovators pp. 26-26

Steven L. Salzberg

NIH funding: The critics respond pp. 26-26

John P. A. Ioannidis and Joshua M. Nicholson

Science alone cannot shape sustainability pp. 26-26

Suraje Dessai, Stavros Afionis and James Van Alstine

Prize marks German journal centenary pp. 26-26

Joan Robinson

Fossils come in to land pp. 28-29

Shuhai Xiao and L. Paul Knauth

Soft heaps and clumpy crystals pp. 30-31

Francesco Sciortino and Emanuela Zaccarelli

Andromeda's extended disk of dwarfs pp. 31-32

R. Brent Tully

Segmentation within scale pp. 32-33

Naama Barkai and Ben-Zion Shilo

Membrane enzyme cuts a fine figure pp. 34-35

Michael S. Wolfe

All in the timing pp. 35-36

Steve Hatfield-Dodds

Break down the walls pp. 36-37

Richard A. Dixon

Non-Fermi-liquid d-wave metal phase of strongly interacting electrons pp. 39-44

Hong-Chen Jiang, Matthew S. Block, Ryan V. Mishmash, James R. Garrison, D. N. Sheng, Olexei I. Motrunich and Matthew P. A. Fisher

Genomic variation landscape of the human gut microbiome pp. 45-50

Siegfried Schloissnig, Manimozhiyan Arumugam, Shinichi Sunagawa, Makedonka Mitreva, Julien Tap, Ana Zhu, Alison Waller, Daniel R. Mende, Jens Roat Kultima, John Martin, Karthik Kota, Shamil R. Sunyaev, George M. Weinstock and Peer Bork

CCR5 is a receptor for Staphylococcus aureus leukotoxin ED pp. 51-55

Francis Alonzo, Lina Kozhaya, Stephen A. Rawlings, Tamara Reyes-Robles, Ashley L. DuMont, David G. Myszka, Nathaniel R. Landau, Derya Unutmaz and Victor J. Torres

Structure of a presenilin family intramembrane aspartate protease pp. 56-61

Xiaochun Li, Shangyu Dang, Chuangye Yan, Xinqi Gong, Jiawei Wang and Yigong Shi

A vast, thin plane of corotating dwarf galaxies orbiting the Andromeda galaxy pp. 62-65

Rodrigo A. Ibata, Geraint F. Lewis, Anthony R. Conn, Michael J. Irwin, Alan W. McConnachie, Scott C. Chapman, Michelle L. Collins, Mark Fardal, Annette M. N. Ferguson, Neil G. Ibata, A. Dougal Mackey, Nicolas F. Martin, Julio Navarro, R. Michael Rich, David Valls-Gabaud and Lawrence M. Widrow

Giant magnetized outflows from the centre of the Milky Way pp. 66-69

Ettore Carretti, Roland M. Crocker, Lister Staveley-Smith, Marijke Haverkorn, Cormac Purcell, B. M. Gaensler, Gianni Bernardi, Michael J. Kesteven and Sergio Poppi

Optical-field-induced current in dielectrics pp. 70-74

Agustin Schiffrin, Tim Paasch-Colberg, Nicholas Karpowicz, Vadym Apalkov, Daniel Gerster, Sascha Mühlbrandt, Michael Korbman, Joachim Reichert, Martin Schultze, Simon Holzner, Johannes V. Barth, Reinhard Kienberger, Ralph Ernstorfer, Vladislav S. Yakovlev, Mark I. Stockman and Ferenc Krausz

Controlling dielectrics with the electric field of light pp. 75-78

Martin Schultze, Elisabeth M. Bothschafter, Annkatrin Sommer, Simon Holzner, Wolfgang Schweinberger, Markus Fiess, Michael Hofstetter, Reinhard Kienberger, Vadym Apalkov, Vladislav S. Yakovlev, Mark I. Stockman and Ferenc Krausz

Probabilistic cost estimates for climate change mitigation pp. 79-83

Joeri Rogelj, David L. McCollum, Andy Reisinger, Malte Meinshausen and Keywan Riahi

The oxidation state of the mantle and the extraction of carbon from Earth’s interior pp. 84-88

Vincenzo Stagno, Dickson O. Ojwang, Catherine A. McCammon and Daniel J. Frost

Ediacaran life on land pp. 89-92

Gregory J. Retallack

Convergent acoustic field of view in echolocating bats pp. 93-96

Lasse Jakobsen, John M. Ratcliffe and Annemarie Surlykke

Inhibition dominates sensory responses in the awake cortex pp. 97-100

Bilal Haider, Michael Häusser and Matteo Carandini

Scaling of embryonic patterning based on phase-gradient encoding pp. 101-105

Volker M. Lauschke, Charisios D. Tsiairis, Paul François and Alexander Aulehla

Restriction of intestinal stem cell expansion and the regenerative response by YAP pp. 106-110

Evan R. Barry, Teppei Morikawa, Brian L. Butler, Kriti Shrestha, Rosemarie de la Rosa, Kelley S. Yan, Charles S. Fuchs, Scott T. Magness, Ron Smits, Shuji Ogino, Calvin J. Kuo and Fernando D. Camargo

Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids pp. 111-115

Xiaoshan Shi, Yunchen Bi, Wei Yang, Xingdong Guo, Yan Jiang, Chanjuan Wan, Lunyi Li, Yibing Bai, Jun Guo, Yujuan Wang, Xiangjun Chen, Bo Wu, Hongbin Sun, Wanli Liu, Junfeng Wang and Chenqi Xu

Coordinated control of replication and transcription by a SAPK protects genomic integrity pp. 116-119

Alba Duch, Irene Felipe-Abrio, Sonia Barroso, Gilad Yaakov, María García-Rubio, Andrés Aguilera, Eulàlia de Nadal and Francesc Posas

DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9 pp. 120-124

Patrice Y. Ohouo, Francisco M. Bastos de Oliveira, Yi Liu, Chu Jian Ma and Marcus B. Smolka

Leadership hurdles pp. 125-126

Lilian Gomory Wu and Wei Jing

Turning point: Sarah Blackford pp. 126-126

Karen Kaplan

First foot pp. 128-128

Deborah Walker