Structural basis for the assembly of the Sxl–Unr translation regulatory complex

Janosch Hennig, Cristina Militti, Grzegorz M. Popowicz, Iren Wang, Miriam Sonntag, Arie Geerlof, Frank Gabel, Fátima Gebauer () and Michael Sattler ()
Additional contact information
Janosch Hennig: Institute of Structural Biology, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, DE-85764, Germany
Cristina Militti: Centre for Genomic Regulation, Gene Regulation, Stem Cells and Cancer Programme, Dr Aiguader 88, 08003 Barcelona, Spain
Grzegorz M. Popowicz: Institute of Structural Biology, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, DE-85764, Germany
Iren Wang: Institute of Structural Biology, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, DE-85764, Germany
Miriam Sonntag: Institute of Structural Biology, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, DE-85764, Germany
Arie Geerlof: Institute of Structural Biology, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, DE-85764, Germany
Frank Gabel: Université Grenoble Alpes, Institut de Biologie Structurale, F-38044 Grenoble, France
Fátima Gebauer: Centre for Genomic Regulation, Gene Regulation, Stem Cells and Cancer Programme, Dr Aiguader 88, 08003 Barcelona, Spain
Michael Sattler: Institute of Structural Biology, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, DE-85764, Germany

Nature, 2014, vol. 515, issue 7526, 287-290

Abstract: The crystal structure of the RNA binding domains of Sxl and Unr with msl2 RNA shows that interwoven interactions establish cooperative assembly of the ternary complex, highlighting how binding of relatively general RNA binding domains to RNA can result in a unique and specific protein–RNA architecture.

Date: 2014
References: Add references at CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.nature.com/articles/nature13693 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:515:y:2014:i:7526:d:10.1038_nature13693

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature13693

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().