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2000, volume 407, articles 6807

NSF calls for funding boost in a bid to reverse decline in maths pp. 931-931

Paul Smaglik

Four more moons for Saturn pp. 931-931

David Adam

UK ministry under fire over handling of BSE research pp. 932-932

David Dickson

Global warming identified as main threat to coral reefs pp. 932-932

Peter Pockley

Carbon sequestration gains support pp. 932-932

Colin Macilwain

US Geological Survey needs more resources, says draft report pp. 933-933

Rex Dalton

Fan mail demands reprieve for delayed US Pluto mission pp. 933-933

William Triplett

Germany gives green light to gene patents pp. 934-934

Quirin Schiermeier

Human Frontier repatriation boost pp. 934-934

Quirin Schiermeier

Japanese court backs woman researcher pp. 935-935

Robert Triendl

Singapore to create nationwide disease database pp. 935-935

David Cyranoski

Clean and green...but are they mean? pp. 938-940

David Adam

Disease should be targeted from all angles pp. 941-941

M. F. Greaves

Returners not welcome at Spanish universities pp. 941-941

Pau Ferrer

No evidence to link polio vaccine with HIV pp. 941-941

Stanley A. Plotkin and Hilary Koprowski

Sexually transmitted retribution pp. 943-943

W. F. Bynum

Ways to get them through the door pp. 944-945

Graham Farmelo

Parasites at the heart of ecology pp. 945-946

Ted J. Case

Life and times of a pioneering polymath pp. 945-945

Thomas R. Dunlap

Science in culture pp. 946-946

Philip Ball

High achiever pp. 947-947

Mott T. Greene

A Leap of Faith pp. 949-949

Prof. Theo Von Hohenheim

ATP, pain and a full bladder pp. 951-952

Sean P. Cook and Edwin W. McCleskey

Convoluted communications pp. 953-953

Amanda Tromans

The red ragged edge pp. 953-955

Brian G. Marsden

Why are some males dull? pp. 955-956

Tore Slagsvold

Clues from corals pp. 956-959

Robert B. Dunbar

Crossroads in carbon pp. 959-959

Liesbeth Venema

Carbon fix for a diatom pp. 959-960

Ulf Riebesell

Insecticides and mosquito-borne disease pp. 961-962

L. McCarroll, M. G. Paton, S. H. P. P. Karunaratne, H. T. R. Jayasuryia, K. S. P. Kalpage and J. Hemingway

Paying for sex is not easy pp. 962-962

S. A. West and A. D. Peters

Regenerating the damaged central nervous system pp. 963-970

Philip J. Horner and Fred H. Gage

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor pp. 971-977

Naoki Kunishima, Yoshimi Shimada, Yuji Tsuji, Toshihiro Sato, Masaki Yamamoto, Takashi Kumasaka, Shigetada Nakanishi, Hisato Jingami and Kosuke Morikawa

Extremely red Kuiper-belt objects in near-circular orbits beyond 40 AU pp. 979-981

S. C. Tegler and W. Romanishin

n-type colloidal semiconductor nanocrystals pp. 981-983

Moonsub Shim and Philippe Guyot-Sionnest

Three-dimensional control of light in a two-dimensional photonic crystal slab pp. 983-986

Edmond Chow, S.Y. Lin, S.G. Johnson, P.R. Villeneuve, J.D. Joannopoulos, J.R. Wendt, G.A. Vawter, W. Zubrzycki, H. Hou and A. Alleman

Geometry-dominated fluid adsorption on sculpted solid substrates pp. 986-989

C. Rascón and A. O. Parry

Influence of mean climate change on climate variability from a 155-year tropical Pacific coral record pp. 989-993

Frank E. Urban, Julia E. Cole and Jonathan T. Overpeck

Widespread uplift and ‘trapdoor’ faulting on Galápagos volcanoes observed with radar interferometry pp. 993-996

Falk Amelung, Sigurjón Jónsson, Howard Zebker and Paul Segall

Unicellular C4 photosynthesis in a marine diatom pp. 996-999

John R. Reinfelder, Anne M. L. Kraepiel and François M. M. Morel

Disruptive sexual selection for plumage coloration in a passerine bird pp. 1000-1003

Erick Greene, Bruce E. Lyon, Vincent R. Muehter, Laurene Ratcliffe, Steven J. Oliver and Peter T. Boag

An area for vergence eye movement in primate frontal cortex pp. 1003-1007

Paul D. Gamlin and Kyunghee Yoon

The mammalian sodium channel BNC1 is required for normal touch sensation pp. 1007-1011

Margaret P. Price, Gary R. Lewin, Sabrina L. McIlwrath, Chun Cheng, Jinghui Xie, Paul A. Heppenstall, Cheryl L. Stucky, Anne G. Mannsfeldt, Timothy J. Brennan, Heather A. Drummond, Jing Qiao, Christopher J. Benson, Deirdre E. Tarr, Ron F. Hrstka, Baoli Yang, Roger A. Williamson and Michael J. Welsh

Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice pp. 1011-1015

Debra A. Cockayne, Sara G. Hamilton, Quan-Ming Zhu, Philip M. Dunn, Yu Zhong, Sanja Novakovic, Annika B. Malmberg, Gary Cain, Amy Berson, Laura Kassotakis, Linda Hedley, Wilhelm G. Lachnit, Geoffrey Burnstock, Stephen B. McMahon and Anthony P. D. W. Ford

Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors pp. 1015-1017

Veronika Souslova, Paolo Cesare, Yanning Ding, Armen N. Akopian, Louise Stanfa, Rie Suzuki, Katherine Carpenter, Anthony Dickenson, Susan Boyce, Ray Hill, Daniela Nebenius-Oosthuizen, Andrew J.H. Smith, Emma J. Kidd and John N. Wood

Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum pp. 1018-1022

Lúcio H. Freitas-Junior, Emmanuel Bottius, Lindsay A. Pirrit, Kirk W. Deitsch, Christine Scheidig, Francoise Guinet, Ulf Nehrbass, Thomas E. Wellems and Artur Scherf

Matrix proteins can generate the higher order architecture of the Golgi apparatus pp. 1022-1026

Joachim Seemann, Eija Jokitalo, Marc Pypaert and Graham Warren

Steps and fluctuations of Listeria monocytogenes during actin-based motility pp. 1026-1029

Scot C. Kuo and James L. McGrath

Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin pp. 1029-1034

Luca Pellegrini, David F. Burke, Frank von Delft, Barbara Mulloy and Tom L. Blundell

2000, volume 407, articles 6806

Tissue donors use their influence in deal over gene patent terms pp. 821-821

Paul Smaglik

Spain's science figures under fire pp. 821-821

Xavier Bosch

Mbeki agrees to step back from AIDS debate pp. 822-822

Michael Cherry

UK to make the northwest a post-genomics hotspot pp. 822-822

David Adam

NSF puts big money into complex ecology pp. 823-823

Colin Macilwain

Deep roots of Nazi science revealed pp. 823-824

Alison Abbott and Quirin Schiermeier

Canada plans reduction in greenhouse-gas emissions pp. 824-824

David Spurgeon

US court slashes damages in polymerase-β theft case pp. 824-824

Rex Dalton

French take physics archives into the future pp. 825-825

Declan Butler

Anger as Princeton closes 'inspirational' museum pp. 825-825

Rex Dalton

For my next trick pp. 828-829

Paul Smaglik

India's finest, for hire pp. 830-831

K. S. Jayaraman

Did civil reactors supply plutonium for weapons? pp. 833-834

K. W. J. Barnham, J. Nelson and R. A. Stevens

Careers in science offer women an unusual bonus: immortality pp. 833-833

Dean Falk

Enigma thief stole a very special machine pp. 833-833

E. T. Hall

Achievers should stay to aid Brazilian science pp. 834-834

Maria J. Hötzel

...yet the path is strewn with needless obstacles pp. 834-834

Ricardo de Souza Pereira

If free speech costs lives that's a high price to pay pp. 834-834

Simon Wain-Hobson and Robin A. Weiss

A many-feathered tale pp. 835-836

Susan E. Lederer

A warm topic for cogitation pp. 836-837

Andrew R. Cossins

Cultivating the power of the empire pp. 836-836

Lewis Pyenson

Catch as catch can? pp. 837-838

John Godfrey

Science in culture pp. 838-838

Martin Kemp

Prophets without honour? pp. 839-839

R. M. Simmons

Subpoenaed in Syracuse pp. 841-841

Tom Holt

Identifying cosmic muck pp. 843-844

Harry Y. McSween

A case of bacterial immortality? pp. 844-845

R. John Parkes

Tuning channels for blood pressure pp. 845-847

Nick Standen

Tracing the Earth's evolution pp. 848-849

Mark Rehkämper

Mitrates on the move pp. 849-851

Henry Gee

A world in transition… pp. 851-852

Harry Elderfield

One man's food pp. 852-853

Mitchell A. Lazar

Robert H. Abeles (1926–2000) pp. 854-854

Lizbeth Hedstrom and Perry A. Frey

Genital damage, kicking and early death pp. 855-856

Helen S. Crudgington and Mike T. Siva-Jothy

Is acidification still an ecological threat? pp. 856-857

C. Alewell, B. Manderscheid, H. Meesenburg and J. Bittersohl

reply: Is acidification still an ecological threat? pp. 857-858

J. L. Stoddard, D. S. Jeffries, A. Lükewille, M. Forsius, J. Mannio and A. Wilander

A 3,000-year record of penguin populations pp. 858-858

Liguang Sun, Zhouqing Xie and Junlin Zhao

Glacial/interglacial variations in atmospheric carbon dioxide pp. 859-869

Daniel M. Sigman and Edward A. Boyle

Vasoregulation by the β1 subunit of the calcium-activated potassium channel pp. 870-876

Robert Brenner, Guillermo J. Peréz, Adrian D. Bonev, Delrae M. Eckman, Jon C. Kosek, Steven W. Wiler, Andrew J. Patterson, Mark T. Nelson and Richard W. Aldrich

Molecular emission from single-bubble sonoluminescence pp. 877-879

Yuri T. Didenko, William B. McNamara and Kenneth S. Suslick

Strain effects and phase transitions in photonic resonator crystals pp. 880-883

Harald Pier, Eli Kapon and Michael Moser

Origin of ferromagnetic exchange interactions in a fullerene–organic compound pp. 883-885

Bakhyt Narymbetov, Ales Omerzu, Viktor V. Kabanov, Madoka Tokumoto, Hayao Kobayashi and Dragan Mihailovic

Electrochemically induced annealing of stainless-steel surfaces pp. 885-887

G. T. Burstein, I. M. Hutchings and K. Sasaki

Cooler winters as a possible cause of mass extinctions at the Eocene/Oligocene boundary pp. 887-890

Linda C. Ivany, William P. Patterson and Kyger C. Lohmann

Non-chondritic distribution of the highly siderophile elements in mantle sulphides pp. 891-894

Olivier Alard, William L. Griffin, Jean Pierre Lorand, Simon E. Jackson and Suzanne Y. O'Reilly

Starch grains reveal early root crop horticulture in the Panamanian tropical forest pp. 894-897

Dolores R. Piperno, Anthony J. Ranere, Irene Holst and Patricia Hansell

Isolation of a 250 million-year-old halotolerant bacterium from a primary salt crystal pp. 897-900

Russell H. Vreeland, William D. Rosenzweig and Dennis W. Powers

The proteins of linked genes evolve at similar rates pp. 900-903

Elizabeth J. B. Williams and Laurence D. Hurst

Metapopulation dynamics of bubonic plague pp. 903-906

M. J. Keeling and C. A. Gilligan

Involuntary orienting to sound improves visual perception pp. 906-908

John J. McDonald, Wolfgang A. Teder-Sälejärvi and Steven A. Hillyard

Ghrelin induces adiposity in rodents pp. 908-913

Matthias Tschöp, David L. Smiley and Mark L. Heiman

Repressor activity of Headless/Tcf3 is essential for vertebrate head formation pp. 913-916

Cheol-Hee Kim, Takaya Oda, Motoyuki Itoh, Di Jiang, Kristin Bruk Artinger, Settara C. Chandrasekharappa, Wolfgang Driever and Ajay B. Chitnis

Development of Th1-type immune responses requires the type I cytokine receptor TCCR pp. 916-920

Qi Chen, Nico Ghilardi, Hua Wang, Thad Baker, Ming-Hong Xie, Austin Gurney, Iqbal S. Grewal and Frederic J. de Sauvage

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism pp. 920-923

Ping Wei, Jun Zhang, Margarete Egan-Hafley, Shuguang Liang and David D. Moore

Structure of a serpin–protease complex shows inhibition by deformation pp. 923-926

James A. Huntington, Randy J. Read and Robin W. Carrell

Erratum: Intraprotein radical transfer during photoactivation of DNA photolyase pp. 926-926

Corrine Aubert, Marten H. Vos, Paul Mathis, André P. M. Eker and Klaus Brettel

Erratum: Neural synchrony correlates with surface segregation rules pp. 926-926

Miguel Castelo-Branco, Rainer Goebel, Sergio Neuenschwander and Wolf Singer

2000, volume 407, articles 6805

Medicine Nobel goes to raiders of the brain's chemical secrets pp. 661-661

Alison Abbott

Fathers of electronic revolution are rewarded pp. 662-662

Liesbeth Venema

Plastics that conduct win inventors chemistry prize pp. 662-662

David Adam

Gore and Bush back rise in science spending pp. 663-663

Macilwain Colin

Project offers free mouse sequence pp. 663-664

Paul Smaglik and Alison Abbott

Anger as Spain boosts R&D figures with defence money pp. 664-664

Xavier Bosch

Astrometry mission wins German approval pp. 665-665

Alison Abbott

Ig Nobel glory for levitating frogs and collapsing toilets pp. 665-665

Steve Nadis

Science for art's sake pp. 668-670

Steve Nadis

Poorly conducted (or reported) animal tests put humans at risk pp. 671-671

Victoria Hampshire

Why don't creationists use private schools? pp. 671-671

Jeffrey M. Marcus and Joanne E. Seiff

Survival on the edge: the tube worm's strategy pp. 671-671

John D. Rummel

Activism, scientists and sociobiology pp. 673-674

David L. Hull

Dowsing the human volcano pp. 674-675

Paul Crutzen

Icy displays from before time pp. 675-676

Dale P. Cruikshank

Science in culture pp. 676-676

Philip Ball

A victim of truth pp. 677-677

Sunetra Gupta

Win a Nobel prize! pp. 679-679

Vernor Vinge

Making a potential difference pp. 681-682

George E. Blomgren

Building blocks of movement pp. 682-683

Zoubin Ghahramani

Seeds of doubt pp. 683-685

Peter D. Moore

Stirring times in the Southern Ocean pp. 685-686

Sallie W. Chisholm

Guarding against mutation pp. 687-689

Richard D. Kolodner

Use it or lose it pp. 689-690

Robert D. Holt

Daedalus pp. 690-690

David Jones

Before striking gold in gold-ruby glass pp. 691-692

F. E. Wagner, S. Haslbeck, L. Stievano, S. Calogero, Q. A. Pankhurst and K. -P. Martinek

Facultative worker policing in a wasp pp. 692-693

Kevin R. Foster and Francis L. W. Ratnieks

Maternal effect of Hsf1 on reproductive success pp. 693-694

E. Christians, A. A. Davis, S. D. Thomas and I. J. Benjamin

Coexistence and resource competition pp. 694-694

Per Lundberg, Esa Ranta, Veijo Kaitala and Niclas Jonzén

reply: Coexistence and resource competition pp. 694-694

Jef Huisman and Franz J. Weissing

A mesoscale phytoplankton bloom in the polar Southern Ocean stimulated by iron fertilization pp. 695-702

Philip W. Boyd, Andrew J. Watson, Cliff S. Law, Edward R. Abraham, Thomas Trull, Rob Murdoch, Dorothee C. E. Bakker, Andrew R. Bowie, K. O. Buesseler, Hoe Chang, Matthew Charette, Peter Croot, Ken Downing, Russell Frew, Mark Gall, Mark Hadfield, Julie Hall, Mike Harvey, Greg Jameson, Julie LaRoche, Malcolm Liddicoat, Roger Ling, Maria T. Maldonado, R. Michael McKay, Scott Nodder, Stu Pickmere, Rick Pridmore, Steve Rintoul, Karl Safi, Philip Sutton, Robert Strzepek, Kim Tanneberger, Suzanne Turner, Anya Waite and John Zeldis

Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA pp. 703-710

Galina Obmolova, Changill Ban, Peggy Hsieh and Wei Yang

The crystal structure of DNA mismatch repair protein MutS binding to a G·T mismatch pp. 711-717

Meindert H. Lamers, Anastassis Perrakis, Jacqueline H. Enzlin, Herrie H. K. Winterwerp, Niels de Wind and Titia K. Sixma

Dynamics of singularities in a constrained elastic plate pp. 718-720

Arezki Boudaoud, Pedro Patrício, Yves Couder and Martine Ben Amar

Interconversion of single and double helices formed from synthetic molecular strands pp. 720-723

Volker Berl, Ivan Huc, Richard G. Khoury, Michael J. Krische and Jean-Marie Lehn

Prototype systems for rechargeable magnesium batteries pp. 724-727

D. Aurbach, Z. Lu, A. Schechter, Y. Gofer, H. Gizbar, R. Turgeman, Y. Cohen, M. Moshkovich and E. Levi

Importance of stirring in the development of an iron-fertilized phytoplankton bloom pp. 727-730

Edward R. Abraham, Cliff S. Law, Philip W. Boyd, Samantha J. Lavender, Maria T. Maldonado and Andrew R. Bowie

Effect of iron supply on Southern Ocean CO2 uptake and implications for glacial atmospheric CO2 pp. 730-733

A. J. Watson, D. C. E. Bakker, A. J. Ridgwell, P. W. Boyd and C. S. Law

The possible subduction of continental material to depths greater than 200 km pp. 734-736

Kai Ye, Bolin Cong and Danian Ye

The population genetics of ecological specialization in evolving Escherichia coli populations pp. 736-739

Vaughn S. Cooper and Richard E. Lenski

Natural selection and sympatric divergence in the apple maggot Rhagoletis pomonella pp. 739-742

Kenneth E. Filchak, Joseph B. Roethele and Jeffrey L. Feder

Learning of action through adaptive combination of motor primitives pp. 742-747

Kurt A. Thoroughman and Reza Shadmehr

Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor pp. 747-750

Véronique Corset, Kim Tuyen Nguyen-Ba-Charvet, Christelle Forcet, Emmanuel Moyse, Alain Chédotal and Patrick Mehlen

Somatic support cells restrict germline stem cell self-renewal and promote differentiation pp. 750-754

Amy A. Kiger, Helen White-Cooper and Margaret T. Fuller

Somatic control over the germline stem cell lineage during Drosophila spermatogenesis pp. 754-757

John Tran, Tamara J. Brenner and Stephen DiNardo

The complete sequence of the mucosal pathogen Ureaplasma urealyticum pp. 757-762

John I. Glass, Elliot J. Lefkowitz, Jennifer S. Glass, Cheryl R. Heiner, Ellson Y. Chen and Gail H. Cassell

Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms pp. 762-764

Pradeep K. Singh, Amy L. Schaefer, Matthew R. Parsek, Thomas O. Moninger, Michael J. Welsh and E. P. Greenberg

Messenger RNA targeting of rice seed storage proteins to specific ER subdomains pp. 765-767

Sang-Bong Choi, Changlin Wang, Douglas G. Muench, Kenjirou Ozawa, Vincent R. Franceschi, Yujia Wu and Thomas W. Okita

Correction: BcL-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC pp. 767-767

Shigeomi Shimizu, Masashi Narita and Yoshihide Tsujimoto

The biochemistry of apoptosis pp. 770-776

Michael O. Hengartner

Defying death after DNA damage pp. 777-783

Tina Rich, Rachel L. Allen and Andrew H. Wyllie

Corpse clearance defines the meaning of cell death pp. 784-788

John Savill and Valerie Fadok

CD95's deadly mission in the immune system pp. 789-795

Peter H. Krammer

Apoptosis in development pp. 796-801

Pascal Meier, Andrew Finch and Gerard Evan

Apoptosis in the nervous system pp. 802-809

Junying Yuan and Bruce A. Yankner

From bench to clinic with apoptosis-based therapeutic agents pp. 810-816

Donald W. Nicholson

2000, volume 407, articles 6804

Novartis axes UK transplant centre pp. 547-547

Jessa Netting

US considers moves to relieve morale crisis at energy labs pp. 547-548

Colin Macilwain

Researchers fight for access to Native American skeleton pp. 548-548

Rex Dalton

Reactor refit ignites debate on Japan's fusion strategy pp. 549-549

Robert Triendl

Genomics initiative to decipher 10,000 protein structures pp. 549-549

Paul Smaglik

US lab animals may win in lawsuit pp. 549-549

Meredith Wadman

Age wins as Tokyo revamps retirement rules pp. 550-550

David Cyranoski

Frozen body offers chance to travel back in time pp. 550-550

Quirin Schiermeier and Katrin Stehle

Experts question precautionary approach pp. 551-551

Colin Macilwain

French lab seeks recipe for success pp. 551-551

Declan Butler

The sandman's secrets pp. 554-556

Marina Chicurel

A hundred million points of light pp. 557-557

Govert Schilling

Legal confusion over 'cloning' risks throwing baby out with bathwater pp. 559-559

Martin H. Johnson and Jacek Z. Kubiak

'Benign neglect' of inner city led to TB epidemic pp. 559-559

Deborah Wallace

Loss of taxonomists is a threat to pest control pp. 559-559

M.R. Wilson

Research, innovation and politics pp. 561-562

David M. Hart and Lewis M. Branscomb

Supersymmetric frontiers and beyond pp. 563-564

Gian Francesco Giudice

The counting-house called to account pp. 564-564

Steve Blinkhorn

How the real victory went to science pp. 565-566

Richard Rhodes

Science in culture pp. 566-566

Alison Abbott

Magic beans pp. 567-567

Vaclav Smil

Programmable matter pp. 569-569

Wil McCarthy

Uncertainty in climate change pp. 571-572

Andrew J. Weaver and Francis W. Zwiers

The logic of human learning pp. 572-573

Nick Chater

The long trip to Earth pp. 573-575

Clark R. Chapman

The next big thing pp. 575-575

Josette Chen

Memory needs no reminders pp. 576-577

Stephen Martin and Chris Goodnow

Resolving a methane mystery pp. 577-579

Edward F. DeLong

Optical clocks coming of age pp. 579-580

Patrick Gill

Ti3SiC2 has negligible thermopower pp. 581-582

H. -I. Yoo, M. W. Barsoum and T. El-Raghy

Colour-enhancing protein in blue petals pp. 581-581

Sachiko Fukada-Tanaka, Yoshishige Inagaki, Toshio Yamaguchi, Norio Saito and Shigeru Iida

Asymmetric toes aid underwater swimming pp. 582-583

L. Christoffer Johansson and Ulla M. Lindhe Norberg

Wheat mutation rate after Chernobyl pp. 583-584

Olga Kovalchuk, Yuri E. Dubrova, Andrey Arkhipov, Barbara Hohn and Igor Kovalchuk

Energy constraints on carnivore diet pp. 584-584

Brian K. McNab

Phytochromes and light signal perception by plants—an emerging synthesis pp. 585-591

Harry Smith

Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins pp. 592-598

Anna Lasorella, Michela Noseda, Mercedes Beyna and Antonio Iavarone

Structural determinants of water permeation through aquaporin-1 pp. 599-605

Kazuyoshi Murata, Kaoru Mitsuoka, Teruhisa Hirai, Thomas Walz, Peter Agre, J. Bernard Heymann, Andreas Engel and Yoshinori Fujiyoshi

Efficient delivery of meteorites to the Earth from a wide range of asteroid parent bodies pp. 606-608

D. Vokrouhlický and P. Farinella

Trapping and emission of photons by a single defect in a photonic bandgap structure pp. 608-610

Susumu Noda, Alongkarn Chutinan and Masahiro Imada

Colloidal ordering from phase separation in a liquid- crystalline continuous phase pp. 611-613

Jean-Christophe Loudet, Philippe Barois and Philippe Poulin

Patterning of polymer-supported metal films by microcutting pp. 613-616

Natalie Stutzmann, Theo A. Tervoort, Kees Bastiaansen and Paul Smith

Quantifying the uncertainty in forecasts of anthropogenic climate change pp. 617-620

Myles R. Allen, Peter A. Stott, John F. B. Mitchell, Reiner Schnur and Thomas L. Delworth

Pressure-induced changes in the compression mechanism of aluminous perovskite in the Earth's mantle pp. 620-622

John P. Brodholt

A marine microbial consortium apparently mediating anaerobic oxidation of methane pp. 623-626

Antje Boetius, Katrin Ravenschlag, Carsten J. Schubert, Dirk Rickert, Friedrich Widdel, Armin Gieseke, Rudolf Amann, Bo Barker Jørgensen, Ursula Witte and Olaf Pfannkuche

Modern freshwater microbialite analogues for ancient dendritic reef structures pp. 626-629

Bernard Laval, Sherry L. Cady, John C. Pollack, Christopher P. McKay, John S. Bird, John P. Grotzinger, Derek C. Ford and Harry R. Bohm

Minimization of Boolean complexity in human concept learning pp. 630-633

Jacob Feldman

Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermis pp. 633-636

Mei Li, Arup Kumar Indra, Xavier Warot, Jacques Brocard, Nadia Messaddeq, Shigeaki Kato, Daniel Metzger and Pierre Chambon

Memory B-cell persistence is independent of persisting immunizing antigen pp. 636-642

Mitsuo Maruyama, Kong-Peng Lam and Klaus Rajewsky

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation pp. 642-645

Natalie A. Lissy, Penny K. Davis, Meredith Irwin, William G. Kaelin and Steven F. Dowdy

Role for the p53 homologue p73 in E2F-1-induced apoptosis pp. 645-648

Meredith Irwin, Maria Carmen Marin, Andrew C. Phillips, Ratnam S. Seelan, David I. Smith, Wanguo Liu, Elsa R. Flores, Kenneth Y. Tsai, Tyler Jacks, Karen H. Vousden and William G. Kaelin

S-RNase uptake by compatible pollen tubes in gametophytic self-incompatibility pp. 649-651

Doan-Trung Luu, Xike Qin, David Morse and Mario Cappadocia

The large-scale organization of metabolic networks pp. 651-654

H. Jeong, B. Tombor, R. Albert, Z. N. Oltvai and A.-L. Barabási

Erratum: Determining multiple length scales in rocks pp. 654-654

Yi-Qiao Song, Seungoh Ryu and Pabitra N. Sen

Erratum: Glycosyltransferase activity of Fringe modulates Notch–Delta interactions pp. 654-654

Katja Brücker, Lidia Perez, Henrik Clausen and Stephen Cohen

Western researchers reap rich rewards in eastern institutions pp. 657-658

Diane Gershon

2000, volume 407, articles 6803

Europe urged to set up advisory body on research infrastructure pp. 433-434

Quirin Schiermeier

Canadian science told to look north pp. 433-433

David Spurgeon

UK faces rethink on AIDS treatment pp. 434-434

Karen Birmingham

France backs IT and life sciences pp. 435-436

Declan Butler

NSF aims to inject more maths into biology pp. 435-435

Rex Dalton

Disagreements derail US bill to double research funding… pp. 436-436

Colin Macilwain

…as physical sciences plan lobbying body pp. 436-436

Colin Macilwain

Antibiotic resistance must be monitored, US Senate is told pp. 437-437

Paul Smaglik

Report praises European radio telescope network pp. 437-437

Alison Abbott

A springboard to success pp. 440-441

Colin Macilwain and Ricardo Bonalume Neto

Cheap and cheerful circuits pp. 442-444

David Voss

Don't dismiss chlorine; it could help us to avoid the fate of the Romans pp. 445-445

Ferdinand Engelbeen

Bright future in the stars for big telescopes? pp. 445-445

P. R. Jewell, F. J. Lockman and T. M. Bania

Non-scientists thanked for vital help in Kansas pp. 445-445

Matthew Buechner

Erratum: England and the US corner the journal market pp. 445-445

A.A. Waheed

Science-based security under threat pp. 447-448

David Pines

Taking the heat out of global warming pp. 449-450

Hans von Storch

To the core of consciousness pp. 450-451

Raymond J. Dolan

A dip in the soup, with a pinch of salt pp. 451-452

William J. Hagan

Pitfalls, blind alleys and much more pp. 452-452

Sam Glucksberg

An electromagnetic personality pp. 453-453

James D. Livingston

Through the shaving mirror pp. 455-455

Michael Moorcock and Maurice Richardson

Evolving evolvability pp. 457-458

Linda Partridge and Nicholas H. Barton

Hot heads and cold tails pp. 459-461

Nicholas Arndt

Globins in the brain pp. 461-462

Luc Moens and Sylvia Dewilde

Ducks and darkes pp. 461-461

Chris Mead

The resolution revolution pp. 462-463

Tyler Nordgren

The twenty-first amino acid pp. 463-464

John F. Atkins and Raymond F. Gesteland

Following the crowd pp. 465-466

David J. Low

Use your neighbour's genes pp. 466-467

Don Cowan

Correction: Plankton cooled a greenhouse pp. 467-467

Birger Schmitz

Talking to animals pp. 467-467

David Jones

Correction: Feedback on Gaia pp. 467-467

Jim Gillon

Mark Oliphant (1901–2000) pp. 468-468

Joseph Rotblat

Maternal age and traits in offspring pp. 469-470

Ming-Hseng Wang and Frederick S. vom Saal

Maze-solving by an amoeboid organism pp. 470-470

Toshiyuki Nakagaki, Hiroyasu Yamada and Ágota Tóth

RNA polymerase II elongation through chromatin pp. 471-476

George Orphanides and Danny Reinberg

A yeast prion provides a mechanism for genetic variation and phenotypic diversity pp. 477-483

Heather L. True and Susan L. Lindquist

Direct detection of pulsations of the Cepheid star ζ Gem and an independent calibration of the period–luminosity relation pp. 485-487

B. F. Lane, M. J. Kuchner, A. F. Boden, M. Creech-Eakman and S. R. Kulkarni

Simulating dynamical features of escape panic pp. 487-490

Dirk Helbing, Illés Farkas and Tamás Vicsek

Single photons on demand from a single molecule at room temperature pp. 491-493

B. Lounis and W. E. Moerner

Logical computation using algorithmic self-assembly of DNA triple-crossover molecules pp. 493-496

Chengde Mao, Thomas H. LaBean, John H. Reif and Nadrian C. Seeman

Nano-sized transition-metal oxides as negative-electrode materials for lithium-ion batteries pp. 496-499

P. Poizot, S. Laruelle, S. Grugeon, L. Dupont and J-M. Tarascon

Origins of sulphate in Antarctic dry-valley soils as deduced from anomalous 17O compositions pp. 499-502

Huiming Bao, Douglas A. Campbell, James G. Bockheim and Mark H. Thiemens

Transient high temperatures in mantle plume heads inferred from magnesian olivines in Phanerozoic picrites pp. 502-506

R. N. Thompson and S. A. Gibson

Evolutionary instability of ectomycorrhizal symbioses in basidiomycetes pp. 506-508

David S. Hibbett, Luz-Beatriz Gilbert and Michael J. Donoghue

The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum pp. 508-513

Andreas Ruepp, Werner Graml, Martha-Leticia Santos-Martinez, Kristin K. Koretke, Craig Volker, H. Werner Mewes, Dmitrij Frishman, Susanne Stocker, Andrei N. Lupas and Wolfgang Baumeister

An SNP map of the human genome generated by reduced representation shotgun sequencing pp. 513-516

David Altshuler, Victor J. Pollara, Chris R. Cowles, William J. Van Etten, Jennifer Baldwin, Lauren Linton and Eric S. Lander

An SNP map of human chromosome 22 pp. 516-520

J. C. Mullikin, S. E. Hunt, C. G. Cole, B. J. Mortimore, C. M. Rice, J. Burton, L. H. Matthews, R. Pavitt, R. W. Plumb, S. K. Sims, R. M. R. Ainscough, J. Attwood, J. M. Bailey, K. Barlow, R. M. M. Bruskiewich, P. N. Butcher, N. P. Carter, Y. Chen, C. M. Clee, P. C. Coggill, J. Davies, R. M. Davies, E. Dawson, M. D. Francis, A. A. Joy, R. G. Lamble, C. F. Langford, J. Macarthy, V. Mall, A. Moreland, E. K. Overton-Larty, M. T. Ross, L. C. Smith, C. A. Steward, J. E. Sulston, E. J. Tinsley, K. J. Turney, D. L. Willey, G. D. Wilson, A. A. McMurray, I. Dunham, J. Rogers and D. R. Bentley

A vertebrate globin expressed in the brain pp. 520-523

Thorsten Burmester, Bettina Weich, Sigrid Reinhardt and Thomas Hankeln

Immune control of HIV-1 after early treatment of acute infection pp. 523-526

Eric S. Rosenberg, Marcus Altfeld, Samuel H. Poon, Mary N. Phillips, Barbara M. Wilkes, Robert L. Eldridge, Gregory K. Robbins, Richard T. D'Aquila, Philip J. R. Goulder and Bruce D. Walker

arrow encodes an LDL-receptor-related protein essential for Wingless signalling pp. 527-530

Marcel Wehrli, Scott T. Dougan, Kim Caldwell, Louise O'Keefe, Stephanie Schwartz, Dalit Vaizel-Ohayon, Eyal Schejter, Andrew Tomlinson and Stephen DiNardo

LDL-receptor-related proteins in Wnt signal transduction pp. 530-535

Keiko Tamai, Mikhail Semenov, Yoichi Kato, Rebecca Spokony, Chunming Liu, Yu Katsuyama, Fred Hess, Jean-Pierre Saint-Jeannet and Xi He

An LDL-receptor-related protein mediates Wnt signalling in mice pp. 535-538

Kathleen I. Pinson, Jane Brennan, Susan Monkley, Brian J. Avery and William C. Skarnes

Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase pp. 538-541

Tommaso Simoncini, Ali Hafezi-Moghadam, Derek P. Brazil, Klaus Ley, William W. Chin and James K. Liao

2000, volume 407, articles 6802

UK advised to step up asteroid hunt pp. 275-275

Natasha Loder

Doubts grow over discovery of fossilized ‘dinosaur heart’ pp. 275-276

Rex Dalton

Hunt for Higgs particle wins time for CERN collider pp. 276-276

Alison Abbott

World Bank is urged to give greater priority to science pp. 276-276

Colin Macilwain

NASA reaches out to universities pp. 277-278

William Triplett

European space panel picks new priorities pp. 277-277

Alison Abbott

Case of the stolen Enigma machine takes cryptic turn pp. 278-278

Natasha Loder

Germline gene therapy needs tight control, says US panel pp. 278-278

Paul Smaglik

Japan opens access to mouse cDNA data… pp. 279-279

David Cyranoski

…and to report on strengths and weaknesses of genomics centre pp. 279-279

David Cyranoski

A chemistry set for life pp. 282-284

Trisha Gura

Allowing gene patents could be an expensive mistake for the US pp. 285-285

Hartmut Michel

No room on the carousel for meeting of like minds pp. 285-285

Eleuterio R. Hernandez

Standardized addresses would make web easier pp. 285-285

Sasidharan Rajkumar

The Durban Declaration is not accepted by all pp. 286-286

Gordon T. Stewart Md

Sky was not the limit for music-loving Herschel pp. 286-286

Martin F. Heyworth

Good and bad science in US schools pp. 287-290

Lawrence S. Lerner

Is your journal really necessary? pp. 291-291

Declan Butler

Reborn for a new era pp. 292-293

Rudi Balling

Healing in the genes pp. 292-292

Karin Sitte and Robert Williamson

Psychic secretions pp. 293-293

John C. Marshall

Problems of a glandular nature pp. 293-294

Stafford L. Lightman

Strong growth in the environmental field pp. 294-295

Graham Wood

The art of the saveable pp. 294-294

William J. Sutherland

Chemists exploring a verdant field pp. 295-296

Walter Leitner

More than a breath of fresh air pp. 295-295

Ian Fells

Chemistry's voice heard at last pp. 296-296

Bernadette Bensaude-Vincent

Struggling with complexity pp. 296-296

Gastone Gilli

Across the boundaries pp. 297-297

Albert-László Barabási

Europe's hard forum for soft matter pp. 297-297

Steve Granick and Sung Chul Bae

Making way for complex issues pp. 297-298

William Ditto

Plant power against pollution pp. 298-299

William Purvis

Backing the n-word pp. 298-298

Saul Tendler

The nidus and the crucible pp. 299-300

Moya Meredith Smith

Green and red lights at the cell pp. 299-299

Reinhard Jahn

Crossing the resistance divide pp. 300-300

Eric J. Arts

Down to earth pp. 301-301

Dan H. Yaalon

The Great Goodbye pp. 303-303

Robert Charles Wilson

A moving oxygen story pp. 305-306

Harvey M. Flower

Small subunit, big science pp. 306-307

James R. Williamson

Galactic rotation in real time pp. 307-309

John Kormendy

A radical approach to treatment pp. 309-311

John L. Cleveland and Michael B. Kastan

Calcification and CO2 pp. 311-313

Jean-Pierre Gattuso and Robert W. Buddemeier

Escape from the immune system pp. 313-314

Bruce D. Walker and Philip J. R. Goulder

Post-expressionist flies pp. 314-315

Sarah Bray and David Stein

The sound of silence pp. 315-315

David Jones

Elvin A. Kabat (1914–2000) pp. 316-316

William E. Paul and Rose G. Mage

Membrane changes during hibernation pp. 317-318

Nabil A. Azzam, John M. Hallenbeck and Bechara Kachar

Winter torpor in a large bird pp. 318-318

Gerhard Körtner, R. Mark Brigham and Fritz Geiser

Cloning of mice to six generations pp. 318-319

Teruhiko Wakayama, Yoichi Shinkai, Kellie L. K. Tamashiro, Hiroyuki Niida, D. Caroline Blanchard, Robert J. Blanchard, Atsuo Ogura, Kentaro Tanemura, Makoto Tachibana, Anthony C. F. Perry, Diana F. Colgan, Peter Mombaerts and Ryuzo Yanagimachi

Total silencing by intron-spliced hairpin RNAs pp. 319-320

Neil A. Smith, Surinder P. Singh, Ming-Bo Wang, Peter A. Stoutjesdijk, Allan G. Green and Peter M. Waterhouse

Loosening of plant cell walls by expansins pp. 321-326

Daniel J. Cosgrove

Structure of the 30S ribosomal subunit pp. 327-339

Brian T. Wimberly, Ditlev E. Brodersen, William M. Clemons, Robert J. Morgan-Warren, Andrew P. Carter, Clemens Vonrhein, Thomas Hartsch and V. Ramakrishnan

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics pp. 340-348

Andrew P. Carter, William M. Clemons, Ditlev E. Brodersen, Robert J. Morgan-Warren, Brian T. Wimberly and V. Ramakrishnan

The accelerations of stars orbiting the Milky Way's central black hole pp. 349-351

A. M. Ghez, M. Morris, E. E. Becklin, A. Tanner and T. Kremenek

Onset of antiferromagnetism in heavy-fermion metals pp. 351-355

A. Schröder, G. Aeppli, R. Coldea, M. Adams, O. Stockert, H.v. Löhneysen, E. Bucher, R. Ramazashvili and P. Coleman

Detection of geometric phases in superconducting nanocircuits pp. 355-358

Giuseppe Falci, Rosario Fazio, G. Massimo Palma, Jens Siewert and Vlatko Vedral

Ordering and self-organization in nanocrystalline silicon pp. 358-361

G. F. Grom, D. J. Lockwood, J. P. McCaffrey, H. J. Labbé, P. M. Fauchet, B. White, J. Diener, D. Kovalev, F. Koch and L. Tsybeskov

Direct electrochemical reduction of titanium dioxide to titanium in molten calcium chloride pp. 361-364

George Zheng Chen, Derek J. Fray and Tom W. Farthing

Reduced calcification of marine plankton in response to increased atmospheric CO2 pp. 364-367

Ulf Riebesell, Ingrid Zondervan, Björn Rost, Philippe D. Tortell, Richard E. Zeebe and François M. M. Morel

Increased dissolved oxygen in Pacific intermediate waters due to lower rates of carbon oxidation in sediments pp. 367-370

Lowell D. Stott, William Berelson, Robert Douglas and Donn Gorsline

Variance in ecological consumer–resource interactions pp. 370-374

Lisandro Benedetti-Cecchi

Body image as a visuomotor transformation device revealed in adaptation to reversed vision pp. 374-377

Kaoru Sekiyama, Satoru Miyauchi, Toshihide Imaruoka, Hiroyuki Egusa and Takara Tashiro

IRS-2 pathways integrate female reproduction and energy homeostasis pp. 377-382

Deborah J. Burks, Jaime Font de Mora, Markus Schubert, Dominic J. Withers, Martin G. Myers, Heather H. Towery, Shari L. Altamuro, Carrie L. Flint and Morris F. White

Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines pp. 383-386

Motonari Kondo, David C. Scherer, Toshihiro Miyamoto, Angela G. King, Koichi Akashi, Kazuo Sugamura and Irving L. Weissman

Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia pp. 386-390

Todd M. Allen, David H. O'Connor, Peicheng Jing, John L. Dzuris, Bianca R. Mothé, Thorsten U. Vogel, Ed Dunphy, Max E. Liebl, Carol Emerson, Nancy Wilson, Kevin J. Kunstman, Xiaochi Wang, David B. Allison, Austin L. Hughes, Ronald C. Desrosiers, John D. Altman, Steven M. Wolinsky, Alessandro Sette and David I. Watkins

Superoxide dismutase as a target for the selective killing of cancer cells pp. 390-395

Peng Huang, Li Feng, Elizabeth A. Oldham, Michael J. Keating and William Plunkett

A chemical switch for inhibitor-sensitive alleles of any protein kinase pp. 395-401

Anthony C. Bishop, Jeffrey A. Ubersax, Dejah T. Petsch, Dina P. Matheos, Nathanael S. Gray, Justin Blethrow, Eiji Shimizu, Joe Z. Tsien, Peter G. Schultz, Mark D. Rose, John L. Wood, David O. Morgan and Kevan M. Shokat

The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans pp. 401-405

Zhaolan Zhou, Ming-juan Luo, Katja Straesser, Jun Katahira, Ed Hurt and Robin Reed

Chromodomains are protein–RNA interaction modules pp. 405-409

Asifa Akhtar, Daniele Zink and Peter B. Becker

Image reconstructions of helical assemblies of the HIV-1 CA protein pp. 409-413

Su Li, Christopher P. Hill, Wesley I. Sundquist and John T. Finch

Correction: Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells pp. 413-413

Christian Kurts, Francis R. Carbone, Matthew F. Krummel, Karl M. Koch, Jacques F. A. P. Miller and William R. Heath

Erratum: How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis pp. 413-413

Richard Glynne, Srinivas Akkaraju, James I. Healy, Jane Rayner, Christopher C. Goodnow and David H. Mack

Taiwan backs experience in quest for biotech success pp. 417-418

David Swinbanks and David Cyranoski

Stepping out from the semiconductor shadow pp. 418-418

David Cyranoski

Building a progressive sci-tech island pp. 419-419

David Cyranoski

A science giant rises out of the rice fields pp. 420-420

David Cyranoski

Nicky Lu — entrepreneur pp. 421-421

David Cyranoski

Beating the odds pp. 422-423

David Cyranoski

Homeless, but heading for success pp. 424-424

David Swinbanks

The rodent route to celebrity pp. 425-425

David Cyranoski

Bridging the gap pp. 426-426

David Swinbanks

Unfavourable economics put postdocs across Europe under strain pp. 427-428

Natasha Loder

Finding a focus for European postdocs pp. 427-427

Natasha Loder

Trouble at home pp. 428-428

Xavier Bosch

Postdocs reject academic research pp. 429-430

Potter Wickware

Organization pays pp. 430-430

Potter Wickware

2000, volume 407, articles 6801

Tests fail to support claims for origin of AIDS in polio vaccine pp. 117-117

David Dickson

Physicists haunted by hints of Higgs boson pp. 118-118

Alison Abbott

Gore pledges support for bioscience pp. 118-118

Meredith Wadman

Heavyweight academies take up the cause of US postdocs pp. 119-119

Jessa Netting

France finally picks Parisian site for new synchrotron pp. 119-120

Declan Butler

Neuroscientist to lead Salk Institute pp. 120-120

Rex Dalton

Drug-resistant HIV shows a worrying increase in the UK pp. 120-120

Natasha Loder

US panel draws blank on Gulf War symptoms pp. 121-121

Meredith Wadman

Global warming threatens extinction for many species pp. 121-121

David Spurgeon

What price the Olympian ideal? pp. 124-125

Alison Abbott

The lot of the dope police pp. 125-125

Alison Abbott

A storm over steroids pp. 126-126

Alison Abbott

Step back to see how science and humanity fit in the big picture pp. 128-128

Klaus Jaffe

Patent dispute hangs over kringle 5 pp. 128-128

Judah Folkman

When peer review fails pp. 129-130

Stephen Bodner and Christopher Paine

Sporting colours pp. 131-132

Kenan Malik

At the edges of life pp. 132-133

Knut Schmidt-Nielsen

Surfing the nebulae, churning the waters pp. 133-134

J. L. Heilbron

Science in culture pp. 134-134

Robert S. Root-Bernstein

Creative tension pp. 135-135

Keith G. Davies

Madame Bovary, c'est moi pp. 137-137

Dan Simmons

Currents without borders pp. 139-140

Paul M. Grant

Sky-high Asian imports pp. 140-140

Heike Langenberg

Bundling up excitement pp. 141-143

Jeffrey D. Rothstein

Plankton cooled a greenhouse pp. 143-144

Birger Schmitz

The specifics of membrane fusion pp. 144-146

Suzie J. Scales, Jason B. Bock and Richard H. Scheller

Imaging black holes pp. 146-147

Nicholas White

Lipid rafts and insulin action pp. 147-148

Michael P. Czech

Vitamins and minerals pp. 148-148

David Jones

Sexual conflict and speciation pp. 149-150

Tom Tregenza, Roger K. Butlin and Nina Wedell

Immunocontraception of African elephants pp. 149-149

R. A. Fayrer-Hosken, D. Grobler, J. J. Van Altena, H. J. Bertschinger and J. F. Kirkpatrick

Properties of a new soft magnetic material pp. 150-151

S. X. Wang, N. X. Sun, M. Yamaguchi and S. Yabukami

reply: Sexual conflict and speciation pp. 150-150

S. Gavrilets

KSHV-like herpesviruses in chimps and gorillas pp. 151-152

Vincent Lacoste, Philippe Mauclre, Guy Dubreuil, John Lewis, Marie-Claude Georges-Courbot and Antoine Gessain

Fish do not avoid survey vessels pp. 152-152

P. G. Fernandes, A. S. Brierley, E. J. Simmonds, N. W. Millard, S. D. McPhail, F. Armstrong, P. Stevenson and M. Squires

Compartmental specificity of cellular membrane fusion encoded in SNARE proteins pp. 153-159

James A. McNew, Francesco Parlati, Ryouichi Fukuda, Robert J. Johnston, Keren Paz, Fabienne Paumet, Thomas H. Söllner and James E. Rothman

Laboratory detection of X-ray fringes with a grazing-incidence interferometer pp. 160-162

Webster Cash, Ann Shipley, Steve Osterman and Marshall Joy

Enhanced supercurrent density in polycrystalline YBa2Cu3O7-δ at 77 K from calcium doping of grain boundaries pp. 162-164

G. Hammerl, A. Schmehl, R. R. Schulz, B. Goetz, H. Bielefeldt, C. W. Schneider, H. Hilgenkamp and J. Mannhart

Thin films of fullerene-like MoS2 nanoparticles with ultra-low friction and wear pp. 164-167

Manish Chhowalla and Gehan A. J. Amaratunga

Helical self-assembled polymers from cooperative stacking of hydrogen-bonded pairs pp. 167-170

J. H. K. Ky Hirschberg, Luc Brunsveld, Aissa Ramzi, Jef A. J. M. Vekemans, Rint P. Sijbesma and E. W. Meijer

Termination of global warmth at the Palaeocene/Eocene boundary through productivity feedback pp. 171-174

Santo Bains, Richard D. Norris, Richard M. Corfield and Kristina L. Faul

Earthquake-induced changes in a hydrothermal system on the Juan de Fuca mid-ocean ridge pp. 174-177

H. Paul Johnson, Michael Hutnak, Robert P. Dziak, Christopher G. Fox, Istvan Urcuyo, James P. Cowen, John Nabelek and Charles Fisher

Bacterial photosynthesis in surface waters of the open ocean pp. 177-179

Z. S. Kolber, C. L. Van Dover, R. A. Niederman and P. G. Falkowski

Large-scale processes and the Asian bias in species diversity of temperate plants pp. 180-182

Hong Qian and Robert E. Ricklefs

Genetic evidence for female host-specific races of the common cuckoo pp. 183-186

H. Lisle Gibbs, Michael D. Sorenson, Karen Marchetti, M. de L. Brooke, N. B. Davies and Hiroshi Nakamura

WNT signalling molecules act in axis formation in the diploblastic metazoan Hydra pp. 186-189

Bert Hobmayer, Fabian Rentzsch, Kerstin Kuhn, Christoph M. Happel, Christoph Cramer von Laue, Petra Snyder, Ute Rothbächer and Thomas W. Holstein

Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons pp. 189-194

Shigeo Takamori, Jeong Seop Rhee, Christian Rosenmund and Reinhard Jahn

Topological restriction of SNARE-dependent membrane fusion pp. 194-198

Francesco Parlati, James A. McNew, Ryouichi Fukuda, Rebecca Miller, Thomas H. Söllner and James E. Rothman

Functional architecture of an intracellular membrane t-SNARE pp. 198-202

Ryouichi Fukuda, James A. McNew, Thomas Weber, Francesco Parlati, Thomas Engel, Walter Nickel, James E. Rothman and Thomas H. Söllner

CAP defines a second signalling pathway required for insulin-stimulated glucose transport pp. 202-207

Christian A. Baumann, Vered Ribon, Makoto Kanzaki, Debbie C. Thurmond, Silvia Mora, Satoshi Shigematsu, Perry E. Bickel, Jeffrey E. Pessin and Alan R. Saltiel

Activation of heat-shock response by an adenovirus is essential for virus replication pp. 207-211

Jolanta B. Glotzer, Mediyha Saltik, Susanna Chiocca, Anne-Isabelle Michou, Pope Moseley and Matt Cotten

Peroxynitrite reductase activity of bacterial peroxiredoxins pp. 211-215

Ruslana Bryk, Patrick Griffin and Carl Nathan

Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase pp. 215-218

John W. Trauger, Rahul M. Kohli, Henning D. Mootz, Mohamed A. Marahiel and Christopher T. Walsh

A genetic blueprint for cardiac development pp. 221-226

Deepak Srivastava and Eric N. Olson

Genomic circuits and the integrative biology of cardiac diseases pp. 227-232

Kenneth R. Chien

Atherosclerosis pp. 233-241

Aldons J. Lusis

Vascular-specific growth factors and blood vessel formation pp. 242-248

George D. Yancopoulos, Samuel Davis, Nicholas W. Gale, John S. Rudge, Stanley J. Wiegand and Jocelyn Holash

Angiogenesis in cancer and other diseases pp. 249-257

Peter Carmeliet and Rakesh K. Jain

Thrombin signalling and protease-activated receptors pp. 258-264

Shaun R. Coughlin

Perspectives for vascular genomics pp. 265-269

Edward M. Rubin and Alan Tall

Vascular biology: a route to novel cardiovascular drugs pp. 270-270

Tommy Abrahamsson, Adriano Henney, German Camejo and Mikael Dohlsten

2000, volume 407, articles 6800

Britain may boost protection of researchers from intimidation… pp. 3-3

Natasha Loder

…as German activists wage propaganda war pp. 3-3

Quirin Schiermeier

Construction starts on largest telescope in the south pp. 4-4

Michael Cherry

Japan's desire to lead in IT fuels latest budget requests pp. 4-4

David Cyranoski

US forest fires send ecology experiments up in smoke pp. 5-5

Paul Smaglik

Electricity debt could mean lights out for Russian virus institute pp. 5-6

Carl Levitin and Alison Abbott

Californian centre will test medical uses of cannabis pp. 6-6

Rex Dalton

Researchers practise martian living in the Canadian Arctic pp. 6-6

Steve Nadis

Climate change expert stirs new controversy pp. 7-7

Paul Smaglik

US grant glues ‘virtual cell’ together pp. 7-7

Paul Smaglik

CERN considers chasing up hints of Higgs boson pp. 8-8

Alison Abbott

Trouble in the greenhouse pp. 10-12

Mark Schrope

Debt and poverty turn a disease into an epidemic pp. 13-13

Sanjay Basu, Kedar Mate and Paul E. Farmer

Citation figures suggest that the UK brain drain is a genuine problem pp. 13-13

Alice Sharp Pierson and Peter Cotgreave

Expert witnesses take the stand pp. 15-16

Robert N. Proctor

Varieties of silly experience pp. 17-18

N. David Mermin

Blowing away the smokescreen pp. 18-19

Raphael Mechoulam

Lights in the night sky pp. 19-20

Jay M. Pasachoff

Science in culture pp. 20-20

Philip Ball

Old wine in new bottles pp. 21-21

Jane Maienschein

When I was your age pp. 23-23

John E. Stith

Talk of cannibalism pp. 25-26

Jared M. Diamond

The smallest fullerene pp. 26-27

Martin F. Jarrold

New risks, new gains pp. 27-29

Jeffrey L. Platt

Drifters reveal deep circulation pp. 30-31

Monika Rhein

RNA editing meets DNA shuffling pp. 31-33

Ming Tian and Frederick W. Alt

Spinning molecules to bits pp. 33-34

Manish Gupta and Richard N. Zare

A partner for presenilin pp. 34-35

Dale Schenk

Bouncing a C60 ball pp. 35-36

Leo Kouwenhoven

Cleaning the cleaner pp. 36-36

David Jones

Tyrosine phosphorylation in plant bending pp. 37-37

Kazuhisa Kameyama, Yoshiro Kishi, Masanori Yoshimura, Nobuyuki Kanzawa, Masazumi Sameshima and Takahide Tsuchiya

Good memories of bad events in infancy pp. 38-39

Regina M. Sullivan, Margo Landers, Brian Yeaman and Donald A. Wilson

Imaging light atoms by X-ray holography pp. 38-38

Miklós Tegze, Gyula Faigel, Stefano Marchesini, Michel Belakhovsky and Olivier Ulrich

Investigating T-cell memory pp. 40-40

Alberto Mantovani

reply: Investigating T-cell memory pp. 40-40

Charles H. Maris, Joshy Jacob and David Baltimore

Microtubule motors in mitosis pp. 41-47

David J. Sharp, Gregory C. Rogers and Jonathan M. Scholey

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing pp. 48-54

Gang Yu, Masaki Nishimura, Shigeki Arawaka, Diane Levitan, Lili Zhang, Anurag Tandon, You-Qiang Song, Ekaterina Rogaeva, Fusheng Chen, Toshitaka Kawarai, Agnes Supala, Lyne Levesque, Haung Yu, Dun-Sheng Yang, Erin Holmes, Paul Milman, Yan Liang, Dong Mei Zhang, Dong Hong Xu, Christine Sato, Evgeny Rogaev, Marsha Smith, Christopher Janus, Yanni Zhang, Ruedi Aebersold, Lindsay Farrer, Sandro Sorbi, Amalia Bruni, Paul Fraser and Peter St George-Hyslop

Non-quantized penetration of magnetic field in the vortex state of superconductors pp. 55-57

A. K. Geim, S. V. Dubonos, I. V. Grigorieva, K. S. Novoselov, F. M. Peeters and V. A. Schweigert

Nanomechanical oscillations in a single-C60 transistor pp. 57-60

Hongkun Park, Jiwoong Park, Andrew K. L. Lim, Erik H. Anderson, A. Paul Alivisatos and Paul L. McEuen

Gas-phase production and photoelectron spectroscopy of the smallest fullerene, C20 pp. 60-63

Horst Prinzbach, Andreas Weiler, Peter Landenberger, Fabian Wahl, Jürgen Wörth, Lawrence T. Scott, Marc Gelmont, Daniela Olevano and Bernd v. Issendorff

Chemical characterization of bohrium (element 107) pp. 63-65

R. Eichler, W. Brüchle, R. Dressler, Ch.E. Düllmann, B. Eichler, H. W. Gäggeler, K. E. Gregorich, D. C. Hoffman, S. Hübener, D. T. Jost, U. W. Kirbach, C. A. Laue, V. M. Lavanchy, H. Nitsche, J. B. Patin, D. Piguet, M. Schädel, D. A. Shaughnessy, D. A. Strellis, S. Taut, L. Tobler, Y. S. Tsyganov, A. Türler, A. Vahle, P. A. Wilk and A. B. Yakushev

Mid-depth recirculation observed in the interior Labrador and Irminger seas by direct velocity measurements pp. 66-69

Kara L. Lavender, Russ E. Davis and W. Brechner Owens

Earthquakes as beacons of stress change pp. 69-72

Leonardo Seeber and John G. Armbruster

The earliest known sauropod dinosaur pp. 72-74

Eric Buffetaut, Varavudh Suteethorn, Gilles Cuny, Haiyan Tong, Jean Le Loeuff, Sasidhorn Khansubha and Sutee Jongautchariyakul

Biochemical evidence of cannibalism at a prehistoric Puebloan site in southwestern Colorado pp. 74-78

Richard A. Marlar, Banks L. Leonard, Brian R. Billman, Patricia M. Lambert and Jennifer E. Marlar

Uptake of dissolved organic carbon and trace elements by zebra mussels pp. 78-80

Hudson A. Roditi, Nicholas S. Fisher and Sergio A. Sañudo-Wilhelmy

Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS pp. 81-86

Shuji Shigenobu, Hidemi Watanabe, Masahira Hattori, Yoshiyuki Sakaki and Hajime Ishikawa

Cloned pigs produced by nuclear transfer from adult somatic cells pp. 86-90

Irina A. Polejaeva, Shu-Hung Chen, Todd D. Vaught, Raymond L. Page, June Mullins, Suyapa Ball, Yifan Dai, Jeremy Boone, Shawn Walker, David L. Ayares, Alan Colman and Keith H. S. Campbell

Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice pp. 90-94

Luc J.W. van der Laan, Christopher Lockey, Bradley C. Griffeth, Francine S. Frasier, Carolyn A. Wilson, David E. Onions, Bernhard J. Hering, Zhifeng Long, Edward Otto, Bruce E. Torbett and Daniel R. Salomon

AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration pp. 94-98

Said AbdAlla, Heinz Lother and Ursula Quitterer

Pilus retraction powers bacterial twitching motility pp. 98-102

Alexey J. Merz, Magdalene So and Michael P. Sheetz

TFIIH is negatively regulated by cdk8-containing mediator complexes pp. 102-106

Sasha Akoulitchev, Sergei Chuikov and Danny Reinberg

Domain-specific recruitment of amide amino acids for protein synthesis pp. 106-110

Debra L. Tumbula, Hubert D. Becker, Wei-zhong Chang and Dieter Söll

Erratum: Atomically defined mechanism for proton transfer to a buried redox centre in a protein pp. 110-110

Kaisheng Chen, Judy Hirst, Raul Camba, Christopher A. Bonagura, C. David Stout, Barbara K. Burgess and Fraser A. Armstrong

Correction: The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate pp. 110-110

Koji Yasutomo, Carolyn Doyle, Lucio Miele, Chana Fuchs and Ronald N. Germain

Canada catalyses health research with thirteen virtual institutes pp. 113-114

Diane Gershon